CN107875203A - Fleece-flower root Manufacture of medicinal slices of TCM technique - Google Patents
Fleece-flower root Manufacture of medicinal slices of TCM technique Download PDFInfo
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- CN107875203A CN107875203A CN201710797201.2A CN201710797201A CN107875203A CN 107875203 A CN107875203 A CN 107875203A CN 201710797201 A CN201710797201 A CN 201710797201A CN 107875203 A CN107875203 A CN 107875203A
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- CN
- China
- Prior art keywords
- fleece
- flower root
- root tuber
- piece
- polygonum multiforum
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to the production technology of the prepared slices of Chinese crude drugs.Fleece-flower root Manufacture of medicinal slices of TCM technique, comprises the following steps：Step 1, remove the impurity in polygonum multiforum root tuber；Step 2, the polygonum multiforum root tuber for removing impurity is infiltrated saturating；Step 3, polygonum multiforum root tuber is steamed to inside and outside all in after dark brown, is cut into 2 4mm of thickness piece；Step 4, the piece being cut into is dried.Beneficial effect：Few, the good drug efficacy using prepared slices of Chinese crude drugs nutrient loss made from the inventive method.Chang Yinke is with filling liver kidney, benefiting essence-blood, black beard and hair, strengthening the bones and muscles；And can be used for blood deficiency chlorosis, and dizziness and tinnitus, poliosis, soreness and weakness of waist and knees, under uterine bleeding band, weakness due to chronic disease.
Description
Technical field
The present invention relates to the prepared slices of Chinese crude drugs, and in particular to the production technology of the prepared slices of Chinese crude drugs.
Background technology
The fleece-flower root is perennial plant, and RADIX POLYGONI MULTIFLORI PREPARATA enter liver, the heart, kidney channel have filling liver kidney, beneficial menses, black beard and hair, strengthening the bones and muscles
Function.
But the fleece-flower root should not be used as medicine, it is necessary to take a series of processing, could preferably reach because its health product is big, matter is hard
To drug effect.
The content of the invention
It is an object of the present invention to provide a kind of fleece-flower root Manufacture of medicinal slices of TCM technique, for making fleece-flower root Chinese medicine drink
Piece.
Technical problem solved by the invention can be realized using following technical scheme：
Fleece-flower root Manufacture of medicinal slices of TCM technique, it is characterised in that comprise the following steps：
Step 1, remove the impurity in polygonum multiforum root tuber；
Step 2, the polygonum multiforum root tuber for removing impurity is infiltrated saturating；
Step 3, polygonum multiforum root tuber is steamed to inside and outside all in after dark brown, is cut into thick 2-4mm piece；
Step 4, the piece being cut into is dried.
Impurity in step 1 includes residual stem, soil, dust, mildew or other filths., can also be right in step 1
Block is half-and-half splitted or be cut into the root tuber of big shape.So that polygonum multiforum root tuber is relatively uniform, will not be because of volume differences in step below
It is different big, cause indivedual medicine materical crude slice processing not influence drug effect thoroughly.
In step 2, it can clean, take out, the profit method of 24 hours, make root tuber infiltration saturating by soaking 24 hours.
In step 3, it can be steamed 8 hours, boiled in a covered pot over a slow fire overnight, on next morning daily by the way that the polygonum multiforum root tuber run through is put on steamed tool
Under stir once, steam 3 days 3 nights, obtain inside and outside all in the polygonum multiforum root tuber of dark brown repeatedly according to upper method；
In step 4, can by fleece-flower root piece be dried to 7 one-tenth it is dry when, gained juice when steaming is admixed, is allowed to exhaust, does
It is dry.To be taken back the nutritional ingredient flowed into step 3 in juice by juice, farthest retain nutrition, ensure medicine
Effect.
Step 4, after drying, weed out grey bits.
Beneficial effect：Few, the good drug efficacy using prepared slices of Chinese crude drugs nutrient loss made from this patent method.Often drink can be mended
Liver kidney, benefiting essence-blood, black beard and hair, strengthening the bones and muscles；And it can be used for blood deficiency chlorosis, dizziness and tinnitus, poliosis, soreness and weakness of waist and knees, uterine bleeding
Under band, weakness due to chronic disease.
Embodiment
In order that the technical means, the inventive features, the objects and the advantages of the present invention are easy to understand, enter below
One step illustrates the present invention.
Fleece-flower root Manufacture of medicinal slices of TCM technique, comprises the following steps：
Step 1, remove the impurity in polygonum multiforum root tuber：
Impurity includes residual stem, soil, dust, mildew or other filths.The root tuber of big shape can half-and-half be splitted or
It is cut into block.So that polygonum multiforum root tuber is relatively uniform, and, will not be big because of volume difference in step below, cause at indivedual medicine materical crude slice
Reason does not influence drug effect thoroughly.The fleece-flower root is preferably that grown 3-4, is excavated when autumn, two season of winter tuber fleeceflower leaf are withered, the place of production
Preferably Guizhou Province's Qiandongnan Prefecture of Guizhou Province.What the polygonum multiforum root tuber in step 1 had preferably been dried, or through 80 DEG C of drying 3-4 hours
Dried root.The impurity of dried root can be removed by methods such as wind, sieving, cleanings.
Step 2, the polygonum multiforum root tuber for removing impurity is infiltrated saturating：
It can clean, take out, the profit method of 24 hours, make root tuber infiltration saturating by soaking 24 hours.
Step 3, polygonum multiforum root tuber is steamed to inside and outside all in after dark brown, is cut into thick 2-4mm piece：
It can be steamed 8 hours, boiled in a covered pot over a slow fire overnight, next morning stirs one up and down daily by the way that the polygonum multiforum root tuber run through is put on steamed tool
It is secondary, steamed repeatedly 3 days 3 nights according to upper method, be all in the polygonum multiforum root tuber of dark brown inside and outside acquisition.
Step 4, the piece being cut into is dried：
Can by fleece-flower root piece be dried to 7 one-tenth it is dry when, gained juice when steaming is admixed, is allowed to exhaust, dries.To pass through juice
Water takes back the nutritional ingredient flowed into step 3 in juice, farthest retains nutrition, ensures drug effect.Step 4, dry
After dry, grey bits are weeded out.
Detection case using fleece-flower root piece produced by the present invention is as follows：
1. extracting method is selected
A. the selection of extracting method
B. the selection of extracting concentration
C. extraction time is investigated
Optimum extraction condition can be obtained by above-mentioned A, B, C to handle 30 minutes for 50% EtOH Sonicate.
2. standard curve
Precision weighs reference substance stilbene glycoside 12.3mg in 25ml volumetric flasks, and 0.492mg/ is made with Diluted Alcohol dissolving
Ml standard liquid, then absorption 2.0,3.0,4.0,5.0,6.0,7.0ml in 10ml volumetric flasks, add Diluted Alcohol to quarter respectively
Degree, then sample introduction respectively, standard curve is made.
| Add reference substance volume (ml) | 10ml volumetric flasks contain concentration mg/ml | Peak area |
| 20. | 0.0984 | 1271212 |
| 3.0 | 0.1476 | 1974557 |
| 4.0 | 01968 | 2649342 |
| 5.0 | 0.246 | 3338463 |
| 6.0 | 0.2952 | 4034010 |
| 7.0 | 0.3444 | 4629114 |
Standard curve y=﹣ 58830+13738089.43X r=0.9997
3. the stability experiment of assay method
According to content assaying method, same test sample was determined once every 2 hours, the following test sample sample weighting amount of its result
For 0.2335g
As a result show, test sample is stable in 12 hours.
4. the replica test of assay method
According to content assaying method, same batch of sample is carried out repeatedly to determine (average test at least more than 5 times, i.e., >=5),
Accurate six parts of fleece-flower root piece sample for weighing same lot number is in 25ml volumetric flasks respectively, adds Diluted Alcohol to weigh to scale, ultrasound
Ripple extracts 30 minutes, places, is cooled to room temperature, the weight of less loss is supplied with Diluted Alcohol, filters, takes subsequent filtrate as test sample.
As a result show, the repeatability of test sample is preferably.
5. the precision test of assay method
According to content assaying method, same test liquid is repeatedly measured, investigates its precision.
As a result show, the precision of test sample is good.
6. the measure of the rate of recovery
Precision weighs 5 parts of sample, and scale is dissolved to Diluted Alcohol, and it is 0.1039mg/ml's separately to take 5 parts to be separately added into concentration
Reference substance 10ml, is weighed, and is ultrasonically treated 30 minutes, cooling, and the weight of less loss, filtering are supplied with Diluted Alcohol, and obtained sample is made
For test sample.
The reference substance concentration 0.1039mg/ml of sample lot number 2003072901
As a result show, the rate of recovery of test sample is good.
7. the formulation that content limits
By being determined under " quality standard " item containing survey, 10 batches of sample results see the table below
The content of stilbene glycoside in fleece-flower root piece sample
As a result show, the content of stilbene glycoside is not less than 1.0% in fleece-flower root piece.
Can be that water is made in black soya bean, water is made in vinegar, water is made in wine, water is made in Chinese medicine for soaking, moistening the water of the fleece-flower root,
Can be distilled water.It is preferably added to the water of salt compounded of iodine.After adding sodium chloride in water, infiltration can be adjusted by the content of sodium chloride
Pressure, accelerate impregnation process, and the portion brought into fleece-flower root piece manufacturing process can also be killed by adjusting the content of sodium chloride
Divide microorganism.In addition, iodine is one of essential trace element of human body, the total amount of the iodine in health adult's body for 30 milligrams (20~
50 milligrams), after adding iodine in water, obtained fleece-flower root piece contains iodine, the problem of can improving human body Iodine intake deficiency.In addition,
Iodine can also play certain anti-corrosion, disinfective action.
Steam to inside and outside all in the fleece-flower root of dark brown, preferably cut into slices while hot.The just steamed fleece-flower root is softer, cutting side
Just.More crucially, it is considered that should first cool down and cut into slices again, thus it is possible, on the one hand, because the fleece-flower root quality after cooling is harder, no
It is easily deformed, the thickness of section is easily controlled relatively uniform；On the other hand, fleece-flower root block relative to well cutting fleece-flower root piece more
Thickness, the method cut afterwards can effectively reduce the fragmentation caused by too thin.This patent overcomes the technology prejudice of prior art, first cuts
Cut and cooling down, there are following unexpected benefits：1. during cutting, the fleece-flower root is relatively soft, reduces and cutting tool is wanted
Ask；2. the fleece-flower root piece edge relative smooth cut out, it is not easy to scaling-off.During in order to avoid cutting while hot, the fleece-flower root after cutting
Piece is broken, and the method that the fleece-flower root piece for making to cut out can be used to fall directly into the juice for steaming the fleece-flower root is handled.So
Can is washed open the fleece-flower root piece of cutting using juice, the accumulation deformation of fleece-flower root piece is avoided, moreover, it is also possible to be given using juice
The cooling of fleece-flower root piece or the nutrition for filling into loss.
Because the just steamed fleece-flower root is softer, the fleece-flower root can be cut by way of crossing web plate.The mesh of web plate
It is preferred that the thickness of square grid hole pattern plate is preferably in more than 3mm.To ensure the support strength of web plate, avoid why tuber of multiflower knotweed extruding causes
Deformation.The aperture of the mesh of web plate is first gradually reduced from Single port to another port, then gradually increase.So that both ends are in
Bell mouth shape, the bell-mouth structure of air positioned at cutting front end, the thickness of the side wall between mesh can be reduced, so as to be in blade-like,
Convenient cutting；Bell-mouth structure of air positioned at cutting rear end, it is that Volume Changes caused by expanding with heat and contract with cold, which provide, to be released in cutting process
Between emptying, facilitate the landing of fleece-flower root piece.Aperture at two-port is, length is preferably 2mm-4mm, width be preferably 2mm with
On.To cut out fleece-flower root piece of the thickness as 2mm-4mm.In addition, the aperture at two-port is consistent, it is allowed to web plate cut front end with
Cutting rear end is symmetrical, and person capable of reducing using judges the trouble before and after web plate.
The general principle and principal character and advantages of the present invention of the present invention has been shown and described above.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the simply explanation described in above-described embodiment and specification is originally
The principle of invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its
Equivalent thereof.
Claims (5)
1. fleece-flower root Manufacture of medicinal slices of TCM technique, it is characterised in that comprise the following steps：
Step 1, remove the impurity in polygonum multiforum root tuber；
Step 2, the polygonum multiforum root tuber for removing impurity is infiltrated saturating；
Step 3, polygonum multiforum root tuber is steamed to inside and outside all in after dark brown, is cut into thick 2-4mm piece；
Step 4, the piece being cut into is dried.
2. fleece-flower root Manufacture of medicinal slices of TCM technique according to claim 1, it is characterised in that：Impurity in step 1 includes
Residual stem, soil, dust or mildew.
3. fleece-flower root Manufacture of medicinal slices of TCM technique according to claim 1, it is characterised in that：In step 2, pass through leaching 24
Hour, clean, take out, the profit method of 24 hours, make root tuber infiltration saturating.
4. fleece-flower root Manufacture of medicinal slices of TCM technique according to claim 1, it is characterised in that：In step 3, by that will moisten
Saturating polygonum multiforum root tuber is put on steamed tool, is steamed 8 hours daily, is boiled in a covered pot over a slow fire overnight, next morning is stirred once up and down, is steamed repeatedly 3 days 3 according to upper method
At night, obtain inside and outside all in the polygonum multiforum root tuber of dark brown.
5. fleece-flower root Manufacture of medicinal slices of TCM technique according to claim 1, it is characterised in that：In step 4, what is first
Black piece be dried to 7 one-tenth it is dry when, gained juice when steaming is admixed, is allowed to exhaust, dries.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710797201.2A CN107875203A (en) | 2017-09-06 | 2017-09-06 | Fleece-flower root Manufacture of medicinal slices of TCM technique |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710797201.2A CN107875203A (en) | 2017-09-06 | 2017-09-06 | Fleece-flower root Manufacture of medicinal slices of TCM technique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107875203A true CN107875203A (en) | 2018-04-06 |
Family
ID=61780615
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710797201.2A Pending CN107875203A (en) | 2017-09-06 | 2017-09-06 | Fleece-flower root Manufacture of medicinal slices of TCM technique |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107875203A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101081251A (en) * | 2006-05-29 | 2007-12-05 | 广州中医药大学第二附属医院 | Polygonum multiflorum thunb processing method |
| CN106109600A (en) * | 2016-06-29 | 2016-11-16 | 石丁 | Nine Radix Polygoni Multiflori Preparata production technologies |
-
2017
- 2017-09-06 CN CN201710797201.2A patent/CN107875203A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101081251A (en) * | 2006-05-29 | 2007-12-05 | 广州中医药大学第二附属医院 | Polygonum multiflorum thunb processing method |
| CN106109600A (en) * | 2016-06-29 | 2016-11-16 | 石丁 | Nine Radix Polygoni Multiflori Preparata production technologies |
Non-Patent Citations (1)
| Title |
|---|
| 冉懋雄等: "《现代中药炮制手册》", 31 January 2002, 中国中医药出版社 * |
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Application publication date: 20180406 |