CN103830468A - Alum-free processing method for traditional Chinese medicine rhizoma pinelliae - Google Patents

Alum-free processing method for traditional Chinese medicine rhizoma pinelliae Download PDF

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CN103830468A
CN103830468A CN201410106436.9A CN201410106436A CN103830468A CN 103830468 A CN103830468 A CN 103830468A CN 201410106436 A CN201410106436 A CN 201410106436A CN 103830468 A CN103830468 A CN 103830468A
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rhizoma pinelliae
water
chinese medicine
sheet
preparation process
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白宗利
任玉珍
陈彦琳
杜杰
金锋
梁焕
周林
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China National Corp Of Traditional & Herbal Medicine
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China National Corp Of Traditional & Herbal Medicine
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Abstract

The invention belongs to the field of processing and preparing traditional Chinese medicines, and particularly relates to an alum-free processing method for traditional Chinese medicine pinellia ternate. The method specially comprises the steps of: preparing clean rhizoma pinelliae, classifying in size, adding water which is 8-20 times as much as the prepared rhizoma pinelliae, soaking for 36-48 hours at 30-60DEG C until the cores of rhizoma pinelliae are wetted thoroughly, cooking for 2-4 hours until the tongue feels slightly numb; taking out, slicing and drying to obtain the traditional Chinese medicine rhizoma pinelliae. According to the alum-free processing method for traditional Chinese medicine rhizoma pinelliae, the pinellia ternate is heated and soaked by adopting heating and soaking equipment, so that the addition of auxiliary alum is omitted, the process time can be shortened, the process is not affected by seasons, the irritable toxicity can be effectively reduced, the usage amount of auxiliary materials can be decreased, water changing frequency can be decreased, the loss of active ingredients in pinellia ternate in the production process can be reduced, the operation and industrial production are easy, the product is stable in quality, and good in economic benefits, and has wide market application prospects.

Description

A kind of Chinese medicine Rhizoma Pinelliae without vitriol Preparation process method
Technical field
The invention belongs to Chinese crude drug processing preparation field, particularly a kind of Chinese medicine Rhizoma Pinelliae without vitriol Preparation process method.
Background technology
The prepared slices of Chinese crude drugs are elements that TCM is examined prescription, are also the base stocks of Chinese patent medicine, and the quality of its quality will directly have influence on the embodiment of tcm clinical curative effect, thereby concern the healthy of the people.Low-level production and the application that has influence on the prepared slices of Chinese crude drugs of About The Quality of Sliced Herbal Medicine research.The current ubiquity of Manufacture of medicinal slices of TCM enterprise that production form is extensive, processing technique is simple; Quality control method is poor, quality standard is coarse and crude and single; Because of the problem such as the prepared slice quality that production equipment is backward, automaticity is low, production scale is little is extremely uneven and production and marketing level is low.The existence of these problems has badly influenced TCM and has examined stabilizing and increasing of prescription and Chinese patent medicine clinical efficacy, has also seriously restricted the further excavation to motherland's medicine and pharmacology treasure-house.
Pinellia ternata decoction pieces is to be a kind ofly used for the treatment of that abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm headache, vomiting regurgitation, breast gastral cavity painful abdominal mass are vexed, the Chinese medicine of globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.
The Rhizoma Pinelliae is the dry tuber of aroid Rhizoma Pinelliae Pinellia ternate (Thunb.) Breit..Summer, Qiu Erji excavate, and clean, and remove crust and fibrous root, dry.
Chinese Pharmacopoeia regulation, the Rhizoma Pinelliae has 3 to concoct kind, Rhizoma Pinelliae (process with Alumen), Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) (Rhizoma Zingiberis Recens vitriol system), Rhizoma Pinelliae Preparatum (Radix Glycyrrhizae Calx system).
2010 editions " Chinese Pharmacopoeia " recorded a kind of Rhizoma Pinelliae processing procedure: get the clean Rhizoma Pinelliae, size separately, is dipped to interiorly without the dry heart with 8% white alum solution, and mouth is tasted micro-numb feeling in the tongue that has, and takes out, and cleans, and cuts sheet, is dried.Application number is 201210342432.1, and the patent of invention that name is called " concocting method of a kind of Rhizoma Pinelliae Preparatum and products thereof and application " has been recorded a kind of concocting method of the Rhizoma Pinelliae, and the method step comprises the step that adds other adjuvants such as Radix Glycyrrhizae.Application number is 201010175131.5, and name is called the Chinese patent of " a kind of concocting method of the Chinese medicine Rhizoma Pinelliae " and has recorded a kind of Rhizoma Pinelliae concocting method that need to add alcoholic solution.
Summary of the invention
The defect of background technology is, these concocted methods are comparatively general, the poor operability in actual production process, and product quality is difficult to control, and in immersion process, the effective ingredient of the Rhizoma Pinelliae easily runs off.In traditional handicraft, add the adjuvants such as Alumen easily to cause the chemical medicinal residue such as Alumen excessive, may have side effects, reduced the drug effect of Rhizoma Pinelliae product.
There is technological deficiency for solving in aforementioned background art, the invention provides a kind of Chinese medicine Rhizoma Pinelliae without vitriol Preparation process method.
The method specifically comprises the following steps:
(1) selection: get the Rhizoma Pinelliae;
(2) water soaking: add 8-20 times of water, at the temperature of 30-60 DEG C, soak 36-48 hour, to interior without the dry heart;
(3) decocting in water system: the Rhizoma Pinelliae after water soaking is added to decocting in water 2-4 hour, and very moment is tasted and micro-ly taken out while having numb feeling in the tongue;
(4) section: by boiling, clean after the Rhizoma Pinelliae be cut into Rhizoma Pinelliae sheet;
(5) dry: described Rhizoma Pinelliae sheet to be dried, to obtain final product.
As preferred embodiment, wherein:
For ease of the Rhizoma Pinelliae is fully soaked, in step (1), can be divided into different size according to the size of Rhizoma Pinelliae diameter, carry out respectively following process.Can be diacritical point as preferred mode according to diameter 1.5cm to the sorting of the Rhizoma Pinelliae, specification is less than or equal to 1.5cm and specification and be greater than 1.5cm and process respectively the process of preparing Chinese medicine.
For the benefit of the Rhizoma Pinelliae soaks fully, and step (2) can be carried out the water soaking of the Rhizoma Pinelliae in warm macerating boiling circulation of air flow tank, changes at regular intervals water 1 time, uses airflow stirring 1 time simultaneously.Preferably changing the water spacer time is 12 hours,
As optimal way, in step (4), the thickness of Rhizoma Pinelliae sheet is less than 4mm, taking 1-2mm as good.
As wherein carrying out in heated-air circulation oven the dry of Rhizoma Pinelliae sheet in a kind of embodiment step (5), on each material carrier, be evenly paved with the Rhizoma Pinelliae lamella that thickness is less than 6cm, at 60-70 DEG C of temperature, be dried.As optimal way, for ease of the fully dry dry place of saving of Rhizoma Pinelliae sheet simultaneously, the Rhizoma Pinelliae lamellar spacing on each material carrier, taking 2cm left and right as good, is less than 13% by described Rhizoma Pinelliae chip drying to moisture.
As one preferred embodiment, can comprising the following steps without vitriol Preparation process method of the Chinese medicine Rhizoma Pinelliae of the present invention:
(1) sorting: get the Rhizoma Pinelliae, size separately, is chosen diameter and is less than 1.5cm part;
(2) water soaking: the selected Rhizoma Pinelliae of step (1) is put into warm macerating boiling circulation of air flow tank, add the water of 8 times of amounts, soak 36 hours at 60 DEG C, changed water every 12 hours 1 time and use airflow stirring 1 time;
(3) decocting in water system: the Rhizoma Pinelliae after water soaking is added to decocting in water 2 hours, and very moment is tasted and micro-ly taken out while having numb feeling in the tongue;
(4) section: by boiling, clean after the Rhizoma Pinelliae be cut into 1-2mm Rhizoma Pinelliae sheet;
(5) dry: Rhizoma Pinelliae sheet is put into heated-air circulation oven, the thick Rhizoma Pinelliae lamella of uniform spreading 2cm on each material carrier, temperature is adjusted to 60-70 DEG C, is dried to Rhizoma Pinelliae sheet moisture and is less than 13%, to obtain final product.
As another preferred embodiment, can the comprising the following steps without vitriol Preparation process method of the Chinese medicine Rhizoma Pinelliae of the present invention:
(1) sorting: get the Rhizoma Pinelliae, size separately, is chosen diameter and is greater than 1.5cm part;
(2) water soaking: the selected Rhizoma Pinelliae of step (1) is added to 20 times of water, at the temperature of 50 DEG C, soak 48 hours, changed water every 12 hours 1 time and use airflow stirring 1 time, to interior without the dry heart;
(3) decocting in water system: the Rhizoma Pinelliae after water soaking is added to decocting in water 4 hours, and very moment is tasted and micro-ly taken out while having numb feeling in the tongue;
(4) section: by boiling, clean after the Rhizoma Pinelliae be cut into 1-2mm Rhizoma Pinelliae sheet;
(5) dry: described Rhizoma Pinelliae sheet is put into heated-air circulation oven, the thick Rhizoma Pinelliae lamella of uniform spreading 2cm on each material carrier, temperature is adjusted to 60-70 DEG C, is dried to Rhizoma Pinelliae sheet moisture and is less than 13%, to obtain final product.
The present invention adopts warm macerating equipment to the Rhizoma Pinelliae immersion of heating, remove the interpolation of adjuvant vitriol, shorten the process time, ensure that technique is not subject to seasonal effect, can effectively lower zest toxicity, save supplementary product consumption, reduce and change waterside number, reduced the loss of Rhizoma Pinelliae effective ingredient in production process, easy operating and suitability for industrialized production, and constant product quality, good in economic efficiency, there is market application foreground widely.
Specific embodiments
For ease of the understanding to technical solution of the present invention; below in conjunction with following examples and comparative example, the present invention is described in further detail; but embodiments of the present invention are not limited to this, any embodiment that is equal to that does not depart from basic conception of the present invention, all belongs to protection scope of the present invention.
Comparative example:
Following table is that tradition adds the concocting method of Alumen and of the present invention without vitriol concocting method technical data contrast table:
Figure BDA0000479577600000041
The present invention can shorten 9 days production times by the Rhizoma Pinelliae being carried out to the warm macerating process of preparing Chinese medicine as can be seen from the table, and every production 100Kg Rhizoma Pinelliae can be saved adjuvant Alumen 12.5Kg, reduces and changes number of times 10 times, using water wisely 10m 3, reduce discharge of wastewater 10m 3, save artificial approximately 9 days/people.
Embodiment 1
(1) sorting: by screening machine, the Rhizoma Pinelliae is carried out to sorting according to large and small 2 kinds of specifications, wherein diameter is greater than the large specification of 1.5cm, what diameter was less than 1.5cm is small dimension, selects the small dimension Rhizoma Pinelliae to carry out following process;
(2) water soaking: the small dimension Rhizoma Pinelliae is put into warm macerating boiling circulation of air flow tank, add the water of 8 times of amounts, soak 36 hours at 60 DEG C, changed water every 12 hours 1 time and use airflow stirring 1 time.
(3) decocting in water system: the Rhizoma Pinelliae after water soaking is added to decocting in water 2 hours.
(4) section: the Rhizoma Pinelliae after boiling is cut to 1-2mm thin slice.
(5) dry: Rhizoma Pinelliae sheet is put into heated-air circulation oven, the thick Rhizoma Pinelliae sheet of uniform spreading 2cm on each material carrier, temperature is adjusted to 60-70 DEG C, is dried to Pinellia ternata decoction pieces moisture and is less than 13%.
Embodiment 2
(1) sorting: by screening machine, the Rhizoma Pinelliae is carried out to sorting according to large and small 2 kinds of specifications, wherein diameter is greater than the large specification of 1.5cm, what diameter was less than 1.5cm is small dimension, selects the large specification Rhizoma Pinelliae to carry out following process;
(2) water soaking: the large specification Rhizoma Pinelliae is put into warm macerating boiling circulation of air flow tank, add the water of 20 times of amounts, soak 48 hours at 50 DEG C, changed water every 12 hours 1 time and use airflow stirring 1 time.
(3) decocting in water system: the Rhizoma Pinelliae after water soaking is added to decocting in water 4 hours.
(4) section: the Rhizoma Pinelliae after boiling is cut to 1-2mm thin slice.
(5) dry: Rhizoma Pinelliae sheet is put into heated-air circulation oven, the thick Rhizoma Pinelliae sheet of uniform spreading 2cm on each material carrier, temperature is adjusted to 60-70 DEG C, is dried to Pinellia ternata decoction pieces moisture and is less than 13%.
Determination of extractives: measure according to version " Chinese Pharmacopoeia " " Rhizoma Pinelliae " lower water-soluble extractives algoscopy (annex X A) in 2010
Group Extractum (%)
Embodiment 1 7.9
Embodiment 2 8.2
Within 2010, version " Chinese Pharmacopoeia " regulation Rhizoma Pinelliae extractum must not be less than 7.0%, and the Rhizoma Pinelliae sample that adopts selection process to prepare all meets pharmacopeia requirement.
This written description use-case discloses the present invention, comprises optimal mode, and also makes those skilled in the art can manufacture and use the present invention.Scope that can granted patent of the present invention is defined by the claims, and can comprise other example that those skilled in the art expect.If this other example has the structural element of the literal language that does not differ from claims, if or this other example comprises and the literal language of claims equivalent structure element without substantial differences, within this other example is intended to the scope in claims.Can not cause under inconsistent degree, by reference to all references part of reference is herein incorporated herein.

Claims (10)

  1. The Chinese medicine Rhizoma Pinelliae without a vitriol Preparation process method, the method comprises the following steps:
    (1) selection: get the Rhizoma Pinelliae;
    (2) water soaking: add 8-20 times of water, at the temperature of 30-60 DEG C, soak 36-48 hour, to interior without the dry heart;
    (3) decocting in water system: the Rhizoma Pinelliae after water soaking is added to decocting in water 2-4 hour, and very moment is tasted and micro-ly taken out while having numb feeling in the tongue;
    (4) section: be cut into Rhizoma Pinelliae sheet after boiling;
    (5) dry: described Rhizoma Pinelliae sheet to be dried, to obtain final product.
  2. The Chinese medicine Rhizoma Pinelliae according to claim 1 without vitriol Preparation process method, wherein: the Rhizoma Pinelliae that step (1) is chosen is divided into different size according to diameter, the different size Rhizoma Pinelliae separating according to step (1) in step (2) adds 8-20 times of water separately, at the temperature of 30-60 DEG C, soak 36-48 hour, to interior without the dry heart.
  3. The Chinese medicine Rhizoma Pinelliae according to claim 2 without vitriol Preparation process method, wherein: step (2) is carried out in warm macerating boiling circulation of air flow tank, changes at regular intervals water 1 time, uses airflow stirring 1 time simultaneously.
  4. The Chinese medicine Rhizoma Pinelliae according to claim 3 without vitriol Preparation process method, wherein: when step (2) is soaked in warm macerating boiling circulation of air flow tank, changed water 1 time every 12 hours, use airflow stirring 1 time simultaneously.
  5. According to the arbitrary Chinese medicine Rhizoma Pinelliae described in claim 1-4 without vitriol Preparation process method, wherein: the thickness of step (4) Rhizoma Pinelliae sheet is less than 4mm.
  6. According to claim 5 the Chinese medicine Rhizoma Pinelliae without vitriol Preparation process method, wherein: the thickness of step (4) Rhizoma Pinelliae sheet is 1-2mm.
  7. The Chinese medicine Rhizoma Pinelliae according to claim 5 without vitriol Preparation process method, wherein: in step (5), being dried in heated-air circulation oven of Rhizoma Pinelliae sheet carried out, on each material carrier, be evenly paved with the Rhizoma Pinelliae lamella that thickness is less than 6cm, at 60-70 DEG C of temperature, be dried.
  8. The Chinese medicine Rhizoma Pinelliae according to claim 7 without vitriol Preparation process method, wherein: in step (5), the Rhizoma Pinelliae lamellar spacing on each material carrier is 2cm, and described Rhizoma Pinelliae chip drying to moisture is less than to 13%.
  9. The Chinese medicine Rhizoma Pinelliae according to claim 1 without vitriol Preparation process method, the method comprises the following steps:
    (1) sorting: get the Rhizoma Pinelliae, size separately, is chosen diameter and is less than or equal to 1.5cm part;
    (2) water soaking: the selected Rhizoma Pinelliae of step (1) is put into warm macerating boiling circulation of air flow tank, add the water of 8 times of amounts, soak 36 hours at 60 DEG C, changed water every 12 hours 1 time and use airflow stirring 1 time;
    (3) decocting in water system: the Rhizoma Pinelliae after water soaking is added to decocting in water 2 hours, and very moment is tasted and micro-ly taken out while having numb feeling in the tongue;
    (4) section: by boiling, clean after the Rhizoma Pinelliae be cut into 1-2mm Rhizoma Pinelliae sheet;
    (5) dry: Rhizoma Pinelliae sheet is put into heated-air circulation oven, the thick Rhizoma Pinelliae lamella of uniform spreading 2cm on each material carrier, temperature is adjusted to 60-70 DEG C, is dried to Rhizoma Pinelliae sheet moisture and is less than 13%, to obtain final product.
  10. The Chinese medicine Rhizoma Pinelliae according to claim 1 without vitriol Preparation process method, the method comprises the following steps:
    (1) sorting: get the Rhizoma Pinelliae, size separately, is chosen diameter and is greater than 1.5cm part;
    (2) water soaking: the selected Rhizoma Pinelliae of step (1) is added to 20 times of water, at the temperature of 50 DEG C, soak 48 hours, changed water every 12 hours 1 time and use airflow stirring 1 time, to interior without the dry heart;
    (3) decocting in water system: the Rhizoma Pinelliae after water soaking is added to decocting in water 4 hours, and very moment is tasted and micro-ly taken out while having numb feeling in the tongue;
    (4) section: by boiling, clean after the Rhizoma Pinelliae be cut into 1-2mm Rhizoma Pinelliae sheet;
    (5) dry: described Rhizoma Pinelliae sheet is put into heated-air circulation oven, the thick Rhizoma Pinelliae lamella of uniform spreading 2cm on each material carrier, temperature is adjusted to 60-70 DEG C, is dried to Rhizoma Pinelliae sheet moisture and is less than 13%, to obtain final product.
CN201410106436.9A 2014-03-20 2014-03-20 Alum-free processing method for traditional Chinese medicine rhizoma pinelliae Pending CN103830468A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108126070A (en) * 2018-01-29 2018-06-08 江西青春康源中药饮片有限公司 A kind of concocting method of the water bath with thermostatic control infiltration prepared slices of Chinese crude drugs
CN113101328A (en) * 2020-01-13 2021-07-13 成都中医药大学 Rapid processing method of pinellia ternata
CN113491737A (en) * 2020-04-08 2021-10-12 盈科瑞(天津)创新医药研究有限公司 Pinellia ternata processing method and processed product thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829255A (en) * 2010-05-18 2010-09-15 南京中医药大学 Method for preparing traditional Chinese medicine Pinellia ternata

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829255A (en) * 2010-05-18 2010-09-15 南京中医药大学 Method for preparing traditional Chinese medicine Pinellia ternata

Non-Patent Citations (2)

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Title
张锡纯: "《医学衷中参西录》", 31 January 2002 *
程黎晖: "浅谈半夏炮制的历史沿革", 《中草药》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108126070A (en) * 2018-01-29 2018-06-08 江西青春康源中药饮片有限公司 A kind of concocting method of the water bath with thermostatic control infiltration prepared slices of Chinese crude drugs
CN113101328A (en) * 2020-01-13 2021-07-13 成都中医药大学 Rapid processing method of pinellia ternata
CN113491737A (en) * 2020-04-08 2021-10-12 盈科瑞(天津)创新医药研究有限公司 Pinellia ternata processing method and processed product thereof

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