CN107875030A - A kind of new desquamation compositions and wash hair products - Google Patents
A kind of new desquamation compositions and wash hair products Download PDFInfo
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- CN107875030A CN107875030A CN201711074980.XA CN201711074980A CN107875030A CN 107875030 A CN107875030 A CN 107875030A CN 201711074980 A CN201711074980 A CN 201711074980A CN 107875030 A CN107875030 A CN 107875030A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The present invention discloses a kind of new desquamation compositions and washes hair products, includes the component of following percetage by weight：A) 0.01% 1.5% 2,4 dybenals；B) 0.01% 2% piroctone olamine salt；C) the 0.5% 10% smooth caprylate of sorb；D) 1% 30.0% alcohols NMF；E) 0.05% 5% macromolecule cation polymer；F) water surplus.On the one hand the composition of offer of the present invention, which is applied to cosmetic hair, can break pyrrole Roc alcohol ethyl ketone amine salt to a certain extent in formula using upper limitation, reach the potent anti-dandruff effect of collaboration.And on the other hand it can then reduce excitant of the anti-dandruff agent for scalp.
Description
Technical field
The invention belongs to personal-care supplies field, and in particular to a kind of anti-dandruff hair care composition.Main application
In hair shampoo article.
Background technology
Common disease of the dandruff as skin of head, at least one period can be by dandruff in life by nearly 50% people
Puzzlement.The adult that China there are about 60% is perplexed by dandruff problem to some extent, wherein 15% people's symptom is very tight
Weight.
The generation of dandruff is in general skin dirt, that is, the cuticula of epidermis constantly peels off and caused, belongs to new
A kind of result of old metabolism.The chlosma of mechanism caused by dandruff and its order of severity and distorted proliferation is closely related.Horse traction
Color bacterium amount reproduction causes scalp cuticula hyperplasia, so as to promote corneocyte constantly in the form of the scales of skin that peel off it is extremely de-
Fall, this scales of skin that peel off to come off is dandruff.
The mechanism according to caused by dandruff, the anti-dandruff mechanism of current anti-dandruff cosmetics are broadly divided into cuticula exfoliant, cell
Growth inhibitor, three aspects of anti-microbial agents.Due to cuticula exfoliant, cytostatic agent long-term use can destroy
Epidermal structure upsets the Equilibrium of epidermis, there is certain stimulation and injury to skin, brings the side effects such as decolouring and alopecia.Therefore
It is used as main composition by adding various antifungal drugs to suppress the division of scalp keratinocyte, so as to reduce scalp
The growth of microorganism, reach anti-dandruff purpose, become current anti-dandruff agent Main Trends of The Development.
At present, antimicrobial anti-dandruff agent mainly has piroctone olamine salt (OCT) and pyrithione zinc (ZPT), chlorine miaow bar
Azoles.Wherein for piroctone olamine salt compared with other anti-dandruff and itching-relieving agents, toxicity is relatively low, and solubility property and compound property are excellent,
Mixed with cosmetic material will not occur precipitation or lamination, excitant it is low.But the aqueous solution of piroctone olamine salt has
Color, product coloring is made, and its cost is higher, is also limited by concentration, therefore in the application of cosmetic hair
On significant limitation also be present.And the prevalence of cosmetic material environmental protection in recent years, green and natural tendency so that anti-dandruff agent pair
The excitant of scalp becomes study hotspot, therefore breaks the application limitation of piroctone olamine salt, prepares a kind of new green
The compound desquamation compositions of color, there is splendid prospect in anti-dandruff type cosmetic hair in the market.
The content of the invention
In summary, the present invention is necessary to provide a kind of new desquamation compositions, and anti-dandruff effect is good, to scalp irritation
It is low.
A kind of hair products are washed rather it is necessary to provide including above-mentioned new anti-dandruff combination.
A kind of desquamation compositions, include the component of following percetage by weight：
A) 0.01%-1.5% DCBA；
B) 0.01%-1% piroctone olamine salt；
C) the smooth caprylate of 0.5%-10% sorb；
D) 1%-30.0% alcohols NMF；
E) 0.05%-5% macromolecule cation polymer；
F) water surplus.
Described DCBA content is 0.01%-0.5%, and pyrrole Roc alcohol ethyl ketone amine salt content is 0.1%-
1%, the content of the smooth caprylate of sorb is 2%-10%, and the content of alcohols NMF is 1%-20%, and macromolecule cation polymerize
The content of thing is 1%-5%, water surplus.
Wherein, the weight of the DCBA and pyrrole Roc alcohol ethyl ketone amine salt is than 1:10 to 3:1, more preferably 2,4-
The weight of dybenal and pyrrole Roc alcohol ethyl ketone amine salt is than 3:1.
Wherein, described macromolecule cation polymer be selected from electropositive cationic surfactant or sun from
It is one or more kinds of compound in sub- conditioner, selected from guar hydroxypropyltrimonium chloride, polyquaternium -2, polyquaternary amine
Salt -4, Polyquaternium-10 (cationic fiber system), polyquaternium -7, polyquaternium -11, one kind in polyquaternium -39 or
It is a variety of.
Wherein, the content of described macromolecule cation polymer is 1%-5%, preferably 1%-2%.
Wherein, described alcohols NMF is one or more kinds of compoundings in dihydric alcohol or polyalcohol, can be selected from second
One or more in alcohol, glycerine, propane diols, butanediol, sorbierite, polyethylene glycol (low molecule amount).
Wherein, the content of alcohols NMF is 1%-30.0%, preferably 5-20%, more preferably 5%-10%.
One kind washes hair products, includes the above-described desquamation compositions of 2%-10%.
DCBA (2,4-dichlorobenzyl alcohol, DCBA), also known as 2,4-DCBA, it is
Alcohol compound, molecular formula C7H6Cl2O.DCBA, to slightly yellow crystallization, the slightly soluble in water, is soluble in ethanol, third to be white
The organic solvents such as glycol.DCBA is a kind of broad spectrum antimicrobial agent announced by Boots companies the fifties in 19th century, as activity into
Point or preservative, used for larynx sugar, cosmetics, disinfection drug, oral care product and foot in the product such as emulsifiable paste/lotion.The change
Compound plays bactericidal action by making pathogenic microorganism protein denaturation, precipitation or solidification.
The chemical structural formula of 2,4- dybenals
The smooth caprylate of sorb, synthesized by the D-sorbite in wheat and corn and the octanoic acid in palm oil or coconut oil
, non-formaldehyde releaser, it is a kind of grease of natural origin without halogen, the function with anti-corrosion synergy.The smooth octanoic acid of sorb
Ester is in dermatology and toxicology and harmless under very high concentration, and is beneficial in a manner of collaboration
Play the anti-microbial effect of the alcohol of anti-microbial effect.
The chemical structural formula of the smooth caprylate of sorb
The present invention is a kind of new anti-dandruff hair care composition, is according to the percentage of weight：2,4- dybenals
0.01%-0.5%；Pyrrole Roc alcohol ethyl ketone amine salt 0.1%-5%；The smooth caprylate 0.1%-10% of sorb；Alcohols NMF
0.01%-20%；Macromolecule cation adjuvant 0.01%-1.0%, aqueous carrier surplus.
One or more kinds of compoundings of the described alcohols NMF in dihydric alcohol or polyalcohol, such as ethanol, glycerine, third
Glycol, butanediol, ethanol, sorbierite, polyethylene glycol (low molecule amount) etc..
Described macromolecule cation adjuvant selection includes hydroxypropyl trimethylammonium Guar (youngster) glue, Polyquaternium-10 (sun
Ion fiber system), polyquaternium -7, polyquaternium -39 etc..
Multicomponent alcoholics compound is due to multiple hydroxyls, having preferable compatibility with water, being protected always for cosmetics
Humectant, scalp can be moistened, reduce excitant of the anti-dandruff and itching-relieving agent for scalp to a certain extent.While alcohol compound is also
With certain bacteriostasis, killing action of the anti-dandruff agent to chlosma can be cooperateed with.
Macromolecule cation adjuvant is added into shampoo systems, can be with the anion surfactant phase interaction in formula
Thing is not dissolved in water is formed, or by the affinity with protein on hair, forms cation high molecular film, is killed anti-dandruff
Microbial inoculum is effectively deposited on scalp, so as to more directly act on horse traction color Salmonella, reaches the effect effectively suppressed
Fruit.
DCBA low toxicity material, not teratogenesis, sensitization, not non-stimulated to skin, mucous membrane in finite concentration, can be fast
Speed kills the gram-positive cocci using staphylococcus aureus, Escherichia coli and Candida albicans as representative, Grain-negative respectively
Bacillus and fungi, and killing spore activity.
The smooth caprylate of sorb, is " amphiphilic " molecule, and existing lipophilic group has the cell membrane of hydrophilic radical, bacterium and fungi again
Itself one layer of hydrophily and hydrophobic composition are included, the smooth caprylate of sorb can smoothly enter matching cell membrane knot
Between structure, and interact, so as to change the interface behavior of its cell membrane, cell membrane will be become easier to by antibacterial substance
Infiltration.Pyrrole Roc alcohol ethyl ketone amine salt is promoted to penetrate the cell membrane of thalline, into after cell, pyrrole Roc alcohol ethyl ketone amine salt attack horse traction
The important feature of color bacterium cell, so as to cause cell death, final thalline is dead therewith.
Compared with prior art, outstanding advantages of the invention are：It will be pressed by the smooth caprylate of sorb with 2,4- dybenals
Compounded according to certain proportion and pyrrole Roc alcohol ethyl ketone amine salt, three carries out Synergistic, has broken each other in antimicrobial work
The defects of property, form potent bactericidal composition；Using macromolecule cation polymer as carrier so that anti-dandruff active matter can
Further act on chlosma, efficient sterilizing；Using polyhydric alcohol humectant as auxiliary matrix, the water that can reduce composition is lived
The loss for causing composition to be passed with the time due to water evaporation is spent and reduced, reduces the stimulation to scalp to a certain extent
Property.Therefore, on the one hand this composition, which is applied to cosmetic hair, can break pyrrole Roc alcohol ethyl ketone amine salt to a certain extent
Upper limitation is used in formula, reaches the potent anti-dandruff effect of collaboration.And anti-dandruff agent can be then on the other hand reduced for head
The excitant of skin.
Embodiment
Structure material of the present invention, preparation method and applications are done with reference to some embodiments and further retouched
State.Specific embodiment is of the invention to be further described, non-limiting protection scope of the present invention.
The source of material used in embodiment：
2,4- dybenals：Lark prestige Science and Technology Ltd.；
Pyrrole Roc alcohol ethyl ketone amine salt：Shuan You daily-use chemical industries Co., Ltd of city of Kunshan；
The smooth caprylate of sorb：Clariant chemical industry (China) Co., Ltd；
Glycerine：It is commercially available
Guar hydroxypropyltrimonium chloride：Solvay (Zhangjiagang) Precision Chemical Co., Ltd.
Embodiment 1-4
Formulation weight ratio as described in table 1, by the well mixed obtained desquamation compositions of raw material.
The embodiment 1-4 composition of raw materials of table 1
Embodiment 6
Embodiment 1-5 new anti-dandruff composition is prepared into shampoo, comprised the following steps：
(1) first by EDTA-Na2Add in deionized water, stirring to dissolving；
(2) 80 DEG C are warming up to, sequentially adds laureth sodium sulfovinate 10-15 parts, coconut oleoyl amine MEA1.0-2.5
Part, cocamidopropyl propyl amide hydroxyl sulfo betaine 3-6 parts, hexadecanol 0-1 parts, two (hydrogenated-tallow group) phthalic acid amides
0.5-1 parts, ethylene glycol stearate 0-1 parts, stirring to dissolving；
(3) after above-mentioned solution stirring and dissolving is complete, 45 DEG C are cooled to, is separately added into 1-2 parts polyquaternium -7, poly- two
Stirred after methylsiloxane 3-8 parts, D-pantothenyl aleohol 1-2 parts, adjust pH to 6 or so with citric acid, be separately added into above-described embodiment
Desquamation compositions 2-6 parts, preservative 0.3-1 parts and essence 0.3-0.8 parts in 1-5, stir.
Comparative example 1-3
Formulation weight ratio as described in table 2, by the well mixed obtained desquamation compositions of raw material.
The comparative example composition of raw materials of table 2
| Comparative example 1 | Comparative example 2 | Comparative example 3 | |
| 2,4- dybenals | 0 | 0.05 | 0.5 |
| Pyrrole Roc alcohol ethyl ketone amine salt | 0.01 | 0 | 1.0 |
| The smooth caprylate of sorb | 0.5 | 2 | 0 |
| Glycerine | 1 | 5 | 10 |
| Guar hydroxypropyltrimonium chloride | 0.05 | 1 | 2 |
| Water | Mend to 100 | Mend to 100 | Mend to 100 |
Beneficial effect is tested
The minimal inhibitory concentration of experimental example 1 is tested
The mechanism of anti-dandruff agent selected by the present invention is to cause scalp cuticula mistake by suppressing chlosma amount reproduction
Hyperplasia is spent, it is anti-dandruff so as to have the function that.And minimal inhibitory concentration method is to one of most objective static attribute of dandruff effect.It is logical
Chang Eryan, composition minimal inhibitory concentration is lower, and fungistatic effect is better, i.e., anti-dandruff effect is better.
Method of testing
Malassezia furfur grows in the flask containing culture medium.Then by the dilution of the anti-microbial active matter of dissolving
Liquid is added in the testing tube of the agar containing melting.The inoculum of Malassezia furfur is added in the pipe of each melting, by Guan Xuan
Turn, agar is poured into separated sterilizing culture dish.After flat board is incubated, it is observed that the growth of Malassezia furfur.Not yet
The minimum test dilution for having the anti-microbial active matter of growth is defined as minimum inhibitory concentration (MIC).By relatively more anti-
The MIC value of microbiological active material determines its rejection ability size to Malassezia furfur.
Equipment/reagent
Microbe chlosma, from Guangdong Province microorganism detection center；Conical flask 250ml；Agar medium；
Solvent：Water；2 pipes of testing tube/every kind of anti-microbial active matter/per concentration/active material often to be tested, sterilizing, greatly
Small=18mm × 150mm；2 wares of culture dish/every kind of anti-microbial active matter/per concentration/active material often to be tested,
Sterilizing, size 15mm × 100mm
Experimental procedure
1) Malassezia furfur life in the 250ml conical flasks of the culture medium containing 100ml is made with 320rpm and 30 DEG C of temperature
It is long, until muddy.
2) double dilution method is used, prepares the selected dilution of anti-microbial active matter in a solvent, it is allowed to which sample is lived
Property material dissolves before final test agar is added.
3) dilution that 0.25ml anti-microbial active matters are added in the testing tube of the agar melted containing 9.5ml (is protected
Hold in 45 DEG C of water-baths).
4) added in each testing tube of melting agar 0.25ml chaff horse traction colors Salmonellas (by directly count regulation to
5×105cfu/ml)
5) be vortexed each pipe, and material therein is poured into each culture dish.
6) after agar solidified, overturn flat board and incubate them 5 days at 30 DEG C.
7) visible Malassezia furfur growth on flat board is observed.
Determine MIC value
By the MIC value of more every kind of anti-microbial active matter, the average value conduct of the result of three groups of parallel tests is taken
Experimental result, it is shown in Table 3.
The minimum inhibitory concentration MIC test results of table 3
| Minimal inhibitory concentration value (ppm) | |
| Embodiment 1 | 170 |
| Embodiment 2 | 90 |
| Embodiment 3 | 40 |
| Embodiment 4 | 18 |
| Embodiment 5 | 6 |
| Comparative example 1 | 390 |
| Comparative example 2 | 220 |
| Comparative example 3 | 300 |
It is generally believed that minimal inhibitory concentration MIC has the inhibition to the strain in below 2000ppm, sample.Necessarily
Under experiment condition, the minimal inhibitory concentration MIC of sample is smaller, illustrate the sample suppress the strain ability it is stronger.The tables of data of table 1
Bright, scheme 1-5 desquamation compositions, which are for pityrosporum furfur, has direct inhibitory action effect, the composition pair of scheme 5
The inhibitory action of pityrosporum furfur is the most notable.
Oil-control anti-dandruff and itching-relieving measure of merit：
Volunteer 160 is screened, there is that scalp is fuel-displaced, head is itched, the symptom more than dandruff, is randomly divided into 8 groups, is tried out respectively real
The dandruff control shampoo containing of example and comparative example is applied, is adhered to after trying out 1 month, the effect of shampoo is evaluated according to the readme of volunteer.See
Table 4.
Evaluation criterion is divided into：
(1) significant effect：Scalp is fuel-displaced, head is itched, the symptom more than dandruff is significantly improved；
(2) effectively：Scalp is fuel-displaced, head is itched, the symptom more than dandruff is somewhat reduced；
(3) it is invalid：It is on probation front and rear unchanged.
The dandruff control shampoo containing trial effect of table 4
| Significantly | Effectively | It is invalid | Total effective rate | |
| Embodiment 1 | 10 | 6 | 4 | 80% |
| Embodiment 2 | 10 | 6 | 4 | 80% |
| Embodiment 3 | 13 | 5 | 2 | 90% |
| Embodiment 4 | 15 | 4 | 1 | 95% |
| Embodiment 5 | 16 | 3 | 1 | 95% |
| Comparative example 1 | 7 | 5 | 8 | 60% |
| Comparative example 2 | 9 | 5 | 6 | 70% |
| Comparative example 3 | 10 | 4 | 6 | 70% |
Above result on trial shows that shampoo of the invention has good oil-control, anti-dandruff, antipruritic effect.And according to
More than 95% volunteer's reaction, after the shampoo one month using the present invention, cardability, the stretching force intensity of hair obtain
It is obvious to improve.
It is formulated contrast test
The title of contrast product 1：Yunnan Baiyao supports black hair nursing leaves shampoo (oil-control is antipruritic)
The title of contrast product 2：Head＆Shoulders water moistens anti-dandruff shampoo
By verifying that washing for anti-dandruff shampoo of the present invention be clean, anti-dandruff and submissive work(to the experiment of 80 volunteer's own controls
Can, experiment packet：Control group 1：Yunnan Baiyao supports black hair nursing leaves shampoo (oil-control is antipruritic)；Control group 2：Head＆Shoulders water moistens
Anti-dandruff shampoo；Test group：Anti-dandruff shampoo made from embodiment 6.Tested by 80 volunteers using half a head, (by hair
It is divided into two, half is compared, and second half is tested, and control is then made using the shampoo of control group 1 and control group 2, test group
With the present invention shampoo), by the use of cleannes, anti-dandruff effect, antipruritic effect, compliance, wash after occur the dandruff time as evaluate
Index.Test result is listed in table 3
The shampoo Evaluation results of table 3
Result above shows：The shampoo of the embodiment of the present invention 3 is cleaning compared with the well-known dandruff control shampoo containing in market
Degree, anti-dandruff effect, antipruritic effect and compliance suffer from certain lifting.The shampoo of the embodiment of the present invention 5 goes out after washing
Existing head is itched when meta 4-5 days of dandruff, and Yunnan Baiyao supports the antipruritic leaves shampoo of black oil-control and Head＆Shoulders water profit anti-dandruff shampoo
There was only 2-3 days.
Embodiments of the invention are the foregoing is only, are not intended to limit the scope of the invention, it is every to utilize this hair
The equivalent structure or equivalent flow conversion that bright description is made, or directly or indirectly it is used in other related technology necks
Domain, it is included within the scope of the present invention.
Claims (8)
1. a kind of desquamation compositions, it is characterised in that include the component of following percetage by weight：
A) 0.01%-1.5% DCBA；
B) 0.01%-1% piroctone olamine salt；
C) the smooth caprylate of 0.5%-10% sorb；
D) 1%-30.0% alcohols NMF；
E) 0.05%-5% macromolecule cation polymer；
F) water surplus.
2. desquamation compositions as claimed in claim 1, it is characterised in that：
Described DCBA content is 0.01%-0.5%, and pyrrole Roc alcohol ethyl ketone amine salt content is 0.1%-1%, sorb
The content of smooth caprylate is 2%-10%, and the content of alcohols NMF is 1%-20%, the content of macromolecule cation polymer
For 1%-5%, water surplus.
3. desquamation compositions as claimed in claim 2, it is characterised in that：
The weight of the 2,4- dybenals and pyrrole Roc alcohol ethyl ketone amine salt is than 1:10 to 3:1.
4. desquamation compositions as claimed in claim 3, it is characterised in that：
Described macromolecule cation polymer, which is selected from, has electropositive cationic surfactant or cation opsonizing agent
In it is one or more kinds of compound, selected from guar hydroxypropyltrimonium chloride, polyquaternium -2, polyquaternium -4, poly- season
One or more in ammonium salt -10 (cationic fiber system), polyquaternium -7, polyquaternium -11, polyquaternium -39.
5. desquamation compositions as claimed in claim 4, it is characterised in that：
The content of described macromolecule cation polymer is 1%-2%.
6. desquamation compositions according to claim 5, it is characterised in that：
Described alcohols NMF is one or more kinds of compoundings in dihydric alcohol or polyalcohol, can be selected from ethanol, glycerine, third
One or more in glycol, butanediol, sorbierite, polyethylene glycol (low molecule amount).
7. desquamation compositions according to claim 6, it is characterised in that：
The content of alcohols NMF is 5%-20%.
8. one kind washes hair products, it is characterised in that includes the desquamation compositions described in 2-10% claim any one of 1-7.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108969424A (en) * | 2018-09-29 | 2018-12-11 | 花安堂生物科技集团有限公司 | A kind of moderately removing dandruff anti-pruritic compositions and its preparation method and application |
| CN109106670A (en) * | 2018-10-23 | 2019-01-01 | 长沙小如信息科技有限公司 | A kind of novel desquamation compositions and preparation method |
| CN112274463A (en) * | 2020-09-22 | 2021-01-29 | 广东嘉丹婷日用品有限公司 | Anti-hair loss shampoo and preparation method thereof |
| CN113349213A (en) * | 2021-06-03 | 2021-09-07 | 广州市聚合生物科技有限公司 | Novel environment-friendly sterilization and anticorrosion disinfectant |
| CN113825488A (en) * | 2019-05-14 | 2021-12-21 | 联合利华知识产权控股有限公司 | Hair care compositions comprising 2(1H) -pyridone and piroctone olamine salt |
| CN116869900A (en) * | 2023-08-17 | 2023-10-13 | 广州帝臣生物科技股份有限公司 | Anti-dandruff shampoo and preparation method thereof |
Citations (3)
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| CN109106670A (en) * | 2018-10-23 | 2019-01-01 | 长沙小如信息科技有限公司 | A kind of novel desquamation compositions and preparation method |
| CN113825488A (en) * | 2019-05-14 | 2021-12-21 | 联合利华知识产权控股有限公司 | Hair care compositions comprising 2(1H) -pyridone and piroctone olamine salt |
| CN113825488B (en) * | 2019-05-14 | 2023-07-07 | 联合利华知识产权控股有限公司 | Hair care composition comprising 2 (1H) -pyridone and piroctone olamine salt |
| US11826453B2 (en) | 2019-05-14 | 2023-11-28 | Conopco, Inc. | Hair care composition comprising piroctone olamine |
| CN112274463A (en) * | 2020-09-22 | 2021-01-29 | 广东嘉丹婷日用品有限公司 | Anti-hair loss shampoo and preparation method thereof |
| CN113349213A (en) * | 2021-06-03 | 2021-09-07 | 广州市聚合生物科技有限公司 | Novel environment-friendly sterilization and anticorrosion disinfectant |
| CN116869900A (en) * | 2023-08-17 | 2023-10-13 | 广州帝臣生物科技股份有限公司 | Anti-dandruff shampoo and preparation method thereof |
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