CN107854567A - A kind of Quercetin traditional Chinese medicine oral liquid and preparation method thereof - Google Patents

A kind of Quercetin traditional Chinese medicine oral liquid and preparation method thereof Download PDF

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Publication number
CN107854567A
CN107854567A CN201711198168.8A CN201711198168A CN107854567A CN 107854567 A CN107854567 A CN 107854567A CN 201711198168 A CN201711198168 A CN 201711198168A CN 107854567 A CN107854567 A CN 107854567A
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parts
quercetin
oral liquid
chinese medicine
traditional chinese
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付平国
刘文瑞
欧玉莲
王建买
付嫦娥
刘小军
欧召国
付玉香
李凯
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Hengyang Huashengda Forestry Science And Technology Co Ltd
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Hengyang Huashengda Forestry Science And Technology Co Ltd
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Abstract

The present invention provides a kind of Quercetin traditional Chinese medicine oral liquid, in terms of weight fraction, including the following raw material：100 parts of Quercetin, 25 parts of Herba Selaginellae Doederleinii extract, 40 50 parts of magma light-coloured vinegar, 100 200 parts of mineral water, 0.2 0.8 parts of yeast zinc, 0.05 0.10 parts of eucommia ulmoides extracts, 0.001 0.005 parts of yeast chromium, 0.3 0.5 parts of Co-Q10,13 parts of Honegsukle flower P.E, 10 20 parts of Calyx Seu Fructus Physalis extract.The Quercetin oral liquid is adapted to：Hypertension, high fat of blood and insomniac, cardiac.

Description

A kind of Quercetin traditional Chinese medicine oral liquid and preparation method thereof
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of Quercetin traditional Chinese medicine oral liquid and preparation method thereof.
Background technology
Nowadays, cardiovascular and cerebrovascular disease turns into one of three big killers for threatening health of people, due to the side effect ratio of Western medicine It is larger, therefore raising with long-term treatment, Chinese medicine preparation often turns into first choice.Wherein to refine medicine of the Quercetin as raw material Welcome by patient very much.According to statistics, current China town and country cardiovascular and cerebrovascular diseases occur as 1.2%~1.8%, and the death rate is thousand/ One, for national cardiovascular disease number of the infected in 1,600,000 people or so, the occurrence cause of cardiovascular and cerebrovascular diseases is mainly hypertension, high blood Fat；54% is risen between 1979~1991,12 years, the age is bigger, the easier generation of cardiovascular and cerebrovascular disease, now For more than the 60 years old old man in China more than 1.3 hundred million, China has been enter into aging society.Predicted according to the World Health Organization, 2020 The whole world population of more than 40~60 years old will rise on October 13rd, more than 1,200,000,000,1997 from current 7.4 hundred million Medical science economy report and the World Health Organization were on 2 17th, 1997 numerals announced in Geneva；1994 all dead Dying in number has 40% to die from cardiovascular and cerebrovascular disease.
Quercetin, also known as quercetin, Quercetin, glacial acetic acid is dissolved in, alkaline aqueous solution is in yellow, is practically insoluble in water, second Alcoholic solution taste is very bitter；Medicine can be used as, there is preferable eliminating the phlegm, antitussive action, and have certain antiasthmatic effect；In addition with drop Low blood pressure, enhancing capillary resistance, capillary fragility, reducing blood lipid, coronary artery dilator are reduced, increase coronary blood flow Deng effect.
The content of the invention
An object of the present invention is to provide a kind of Quercetin traditional Chinese medicine oral liquid, and the Quercetin oral liquid can treat more Kind cardiovascular and cerebrovascular disease.
The second object of the present invention is the preparation method for providing above-mentioned Quercetin oral liquid.
Quercetin traditional Chinese medicine oral liquid of the present invention, in terms of weight fraction, including the following raw material：100 parts of Quercetin, selaginella doederlleini carries Take thing 2-5 parts, magma light-coloured vinegar 40-50 parts, yeast zinc 0.2-0.8 parts, eucommia ulmoides extracts 0.05-0.10 parts, yeast chromium 0.001- 0.005 part, Co-Q10 0.3-0.5 parts, Honegsukle flower P.E 1-3 parts, Calyx Seu Fructus Physalis extract 10-20 parts, mineral water 100-200 Part.
Preferably, mineral water is Zhangjiajie mineral water.
Preferably, bauhinia leaf extract 0.1-1 parts can also be added in Quercetin traditional Chinese medicine oral liquid of the present invention.
Preferably, carthamin 0.5-1.0 parts can also be added in Quercetin traditional Chinese medicine oral liquid of the present invention.
Preferably, sea cucumber extract 0.0005-0.0009 parts can also be added in Quercetin traditional Chinese medicine oral liquid of the present invention.
Preferably, Fructus lycii P.E 0.0001-0.0005 parts can also be added in Quercetin traditional Chinese medicine oral liquid of the present invention With notoginseng total saponin 0.5-1.5 parts.
Preferably, rutin 0.0005-0.0009 parts can also be added in Quercetin traditional Chinese medicine oral liquid of the present invention.
Preferably, panaquilon's 0.0005-0.001 parts can also be added in Quercetin traditional Chinese medicine oral liquid of the present invention, ganoderma lucidum is more Sugared 0.0005-0.0009 parts.
The preparation method of Quercetin traditional Chinese medicine oral liquid of the present invention, in turn includes the following steps：
（1）Raw material is weighed up in proportion, is put into defined container；
（2）Raw material in addition to mineral water is mixed；Stirring 45-60 minutes produce Quercetin oral liquid in addition mineral water.
Quercetin oral liquid of the present invention is precipitated as normal phenomenon, using it is front upper and lower rock corkage it is ready-to-drink；Usage and dosage: Orally, a 10-20ml, 3 times a day.
Embodiment
Embodiment of the present invention is described in detail below in conjunction with example, but those skilled in the art will manage Solution, the following example is merely to illustrate the present invention, and should not be taken as limiting the scope of the invention.
Mineral water is Zhangjiajie mineral water in embodiment, and magma light-coloured vinegar meets standard GB/T 18187-2000, with acetic acid Meter, total acid content 4g/100mL.
Embodiment 1
Quercetin 100g Herba Selaginellae Doederleinii extract 3g magma light-coloured vinegars 41g
Mineral water 150g yeast zinc 0.5g eucommia ulmoides extracts 0.08g
The Co-Q10 0.35g Honegsukle flower P.Es 1.9g of yeast chromium 0.003
Calyx Seu Fructus Physalis extract 10g.
Embodiment 2
Quercetin 100g Herba Selaginellae Doederleinii extract 3g magma light-coloured vinegars 45g
Mineral water 150g yeast zinc 0.5g eucommia ulmoides extracts 0.08g
Yeast chromium 0.003g bauhinia leaf extract 0.5g Co-Q10s 0.35g
Honegsukle flower P.E 1.9g Calyx Seu Fructus Physalis extracts 10g.
Embodiment 3
Quercetin 100g Herba Selaginellae Doederleinii extract 3g magma light-coloured vinegars 41g
Mineral water 150g yeast zinc 0.5g eucommia ulmoides extracts 0.08g
Yeast chromium 0.003g carthamin 0.8g Co-Q10s 0.35g
Honegsukle flower P.E 1.9g Calyx Seu Fructus Physalis extracts 10g.
Embodiment 4
Quercetin 100g Herba Selaginellae Doederleinii extract 3g magma light-coloured vinegars 41g
Mineral water 160g yeast zinc 0.5g eucommia ulmoides extracts 0.08g
Yeast chromium 0.003g Co-Q10 0.04g Honegsukle flower P.Es 1.9g
Calyx Seu Fructus Physalis extract 15g sea cucumber extracts 0.7mg.
Embodiment 5
Quercetin 100g Herba Selaginellae Doederleinii extract 3g magma light-coloured vinegars 41g
Mineral water 160g yeast zinc 0.5g eucommia ulmoides extracts 0.08g
Yeast chromium 0.003g carthamin 0.8g Co-Q10s 0.35g
Honegsukle flower P.E 1.9g Calyx Seu Fructus Physalis extract 15g sea cucumber extracts 0.7mg.
Embodiment 6
Quercetin 100g Herba Selaginellae Doederleinii extract 3g magma light-coloured vinegars 41g
Mineral water 15g yeast zinc 0.5g eucommia ulmoides extracts 0.08g
Yeast chromium 0.003g bauhinia leaf extract 0.5g Co-Q10s 0.35g
Honegsukle flower P.E 1.9g Calyx Seu Fructus Physalis extract 15g Fructus lycii P.E 0.3mg notoginseng total saponins 1g.
Embodiment 7
Quercetin 100g Herba Selaginellae Doederleinii extract 4g magma light-coloured vinegars 42g
Mineral water 140g yeast zinc 0.3g eucommia ulmoides extracts 0.06g
Yeast chromium 0.004g bauhinia leaf extract 0.7g Co-Q10s 0.5g
Honegsukle flower P.E 1.9g Calyx Seu Fructus Physalis extract 12g Fructus lycii P.E 0.4mg notoginseng total saponins 0.9g.
Embodiment 8
Quercetin 100g Herba Selaginellae Doederleinii extract 3g magma light-coloured vinegars 41g
Mineral water 130g yeast zinc 0.5g eucommia ulmoides extracts 0.08g
Yeast chromium 0.003g bauhinia leaf extract 0.5g Co-Q10s 0.4g
Honegsukle flower P.E 1.9g Calyx Seu Fructus Physalis extract 15g rutin 0.7mg panaquilons 0.7mg
GL-B 0.6mg.
Embodiment 9
Quercetin 100g Herba Selaginellae Doederleinii extract 4g magma light-coloured vinegars 40g
Mineral water 150g yeast zinc 0.5g eucommia ulmoides extracts 0.08g
Yeast chromium 0.004g bauhinia leaf extract 0.7g Co-Q10s 0.5g
Honegsukle flower P.E 1.8g Calyx Seu Fructus Physalis extract 14g rutin 0.9mg panaquilons 0.6mg
GL-B 0.5mg.
Embodiment 10
Quercetin 100g Herba Selaginellae Doederleinii extract 3g magma light-coloured vinegars 41g
Mineral water 130g yeast zinc 0.5g eucommia ulmoides extracts 0.08g
Yeast chromium 0.003g bauhinia leaf extract 0.5g Co-Q10s 0.4g
Honegsukle flower P.E 1.9g Calyx Seu Fructus Physalis extract 16g sea cucumber extracts 0.8mg
Rutin 0.7mg Fructus lycii P.E 0.6mg notoginseng total saponins 0.7mg.
Embodiment 11
Quercetin 100g Herba Selaginellae Doederleinii extract 4g magma light-coloured vinegars 41g
Mineral water 160g yeast zinc 0.5g eucommia ulmoides extracts 0.08g
Yeast chromium 0.005g bauhinia leaf extract 0.4g Co-Q10s 0.3g
Honegsukle flower P.E 1.7g Calyx Seu Fructus Physalis extract 15g sea cucumber extract 0.6mg rutins 0.6mg
Fructus lycii P.E 0.8mg notoginseng total saponins 0.7mg.
The preparation method of the Quercetin oral liquid of above example comprises the following steps：
（1）Raw material is weighed up in proportion, is put into defined container；
（2）Raw material in addition to mineral water, magma light-coloured vinegar is mixed；Add in mineral water, magma light-coloured vinegar mixed liquor and stir 60 minutes Produce Quercetin oral liquid.
Quercetin oral liquid clinical effectiveness of the embodiment of the present invention is as follows.
Experimental method：
First group:Hypertensive patient 110, it is divided into 11 groups, every group of 10 people, every group of patient takes embodiment 1-11 Quercetin respectively Oral liquid, 3 times a day, each 20mL, 40 minutes warm boiled waters before meals, 30 days are 1 course for the treatment of, take 3 courses for the treatment of.
Second group：Thrombolysis contrasts, and patient 120 is divided into 12 groups, every group of 10 people, every group of Mongolian oak for taking embodiment 1-11 respectively Skin element oral liquid, western drug treatment（Control group）, 3 times a day, each 20mL, 40 minutes warm boiled waters before meals, 30 days are 1 The individual course for the treatment of, two groups of patients are in age, sex, thrombosis position, the course of disease, clinical manifestation etc. comparing difference without conspicuousness.
Experimental result：
First group:The preceding patient's diastolic pressure of medication is more than 180mmHg, and systolic pressure is more than 120mmHg, main suit's giddy, tinnitus, uncomfortable in chest, gas Short, insomnia, head Doppler show that blood vessel has Partial Blocking；After taking 3 courses for the treatment of, blood pressure tends to be steady, and lives and recovers completely.
That takes hypertensive patient after 3 courses for the treatment of the results are shown in Table 1.
The hypertensive patient of table 1 takes the therapeutic effect of Quercetin oral liquid
。
Second group：The evaluated order of severity of thrombosis patients is suitable before medication, and patient is in age, sex, thrombosis position, disease Journey, clinical manifestation etc. comparing difference are without conspicuousness；Medicine of the present invention, without complication, has no haemorrhage during thrombolysis Shape, occasionally there is patient slight gastrointestinal reaction occur, disappeared after giving anti symptom treatment.
The experimental result of thrombosis patients is shown in Table 2 after taking 30 days.
Table 2
。
As can be seen from Table 5, Quercetin oral liquid treatment group is evident in efficacy is higher than western medicine group, and Quercetin oral liquid is molten Bolt is a kind of safely and effectively method.
Above content describes the general principle and principal character of the present invention, and the present invention is not limited to the above embodiments, Without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, and these changes and improvements are all Fall into scope of the claimed invention.

Claims (9)

1. a kind of Quercetin traditional Chinese medicine oral liquid, in terms of parts by weight, including the following raw material：100 parts of Quercetin, Herba Selaginellae Doederleinii extract 2-5 parts, magma light-coloured vinegar 40-50 parts, yeast zinc 0.2-0.8 parts, eucommia ulmoides extracts 0.05-0.10 parts, yeast chromium 0.001- 0.005 part, Co-Q10 0.3-0.5 parts, Honegsukle flower P.E 1-3 parts, Calyx Seu Fructus Physalis extract 10-20 parts, mineral water 100-200 Part.
2. Quercetin traditional Chinese medicine oral liquid according to claim 1, it is characterised in that described mineral water is Zhangjiajie mineral spring Water.
3. Quercetin traditional Chinese medicine oral liquid according to claim 1, it is characterised in that add bauhinia leaf extract 0.1-1 Part.
4. Quercetin traditional Chinese medicine oral liquid according to claim 1, it is characterised in that add carthamin 0.5-1.0 parts.
5. the Quercetin traditional Chinese medicine oral liquid according to claim 1 or 4, it is characterised in that add sea cucumber extract 0.0005- 0.0009 part.
6. Quercetin traditional Chinese medicine oral liquid according to claim 1, it is characterised in that add Fructus lycii P.E 0.0001- 0.0005 part and notoginseng total saponin 0.5-1.5 parts.
7. Quercetin traditional Chinese medicine oral liquid according to claim 1, it is characterised in that add rutin 0.0005-0.0009 parts.
8. Quercetin traditional Chinese medicine oral liquid according to claim 1, it is characterised in that panaquilon's 0.0005-0.001 parts are added, GL-B 0.0005-0.0009 parts.
9. the preparation method of Quercetin traditional Chinese medicine oral liquid according to claim 1, it is characterised in that in turn include the following steps：
（1）Raw material is weighed up in proportion, is put into defined container；
（2）Raw material in addition to mineral water, magma light-coloured vinegar is mixed；Add in mineral water, magma light-coloured vinegar mixed liquor and stir 60 minutes Produce Quercetin oral liquid.
CN201711198168.8A 2017-11-25 2017-11-25 A kind of Quercetin traditional Chinese medicine oral liquid and preparation method thereof Pending CN107854567A (en)

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Publication number Priority date Publication date Assignee Title
FR3104024A1 (en) * 2019-12-09 2021-06-11 Christian STRUNDEN ANTI-ALLERGIC COMPOSITIONS BASED ON SAFFRON AND FLAVONOID
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Application publication date: 20180330