CN102000266A - Medicament for treating cardiovascular and cerebrovascular diseases and brain paralysis and preparation method thereof - Google Patents
Medicament for treating cardiovascular and cerebrovascular diseases and brain paralysis and preparation method thereof Download PDFInfo
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- CN102000266A CN102000266A CN2010105520610A CN201010552061A CN102000266A CN 102000266 A CN102000266 A CN 102000266A CN 2010105520610 A CN2010105520610 A CN 2010105520610A CN 201010552061 A CN201010552061 A CN 201010552061A CN 102000266 A CN102000266 A CN 102000266A
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Abstract
The invention provides a medicament for treating cardiovascular and cerebrovascular diseases and brain paralysis and a preparation method thereof, belonging to the technical field of medicaments. The medicament is prepared by taking the stem of noble dendrobium, radix ophiopogonis, radix scrophulariae, astragalus root, radix rehmanniae, Chinese yam, trichosanthes root, kudzu root, atractylodes rhizome and phellodendron bark as raw material medicines, and the efficacies of the medicines generate the synergistic action to perform the functions of nourishing yin, relieving toxicity, promoting blood circulation and eliminating toxins, thereby achieving the purposes of treating brain paralysis of infants, cardiovascular and cerebrovascular obstruction of middle and old aged people and other diseases. The clinical experiment proves that the medicament of the invention has very good effect on treating brain paralysis of infants and cardiovascular and cerebrovascular obstruction of middle and old aged people; and simultaneously, the medicament can effectively enhance the immunologic function of the human body.
Description
Technical field
The invention belongs to medical technical field, relate to a kind of medicine for the treatment of cardiovascular and cerebrovascular vessel, cerebral palsy and preparation method thereof.
Background technology
Cerebral palsy claims cerebral palsy, cerebral palsy again, is the syndrome that begins from becoming pregnant due to infancy stage non-carrying out property brain injury and the developmental defect, mainly shows as the dyskinesia and abnormal posture.Normal merge dysnoesia, epilepsy, sensory perception obstacle, communication disorder, dystropy and other are unusual.Basic and cerebral palsy of children synonym.Motherland's medical science is called " five kinds of flaccidity in infant ", " five kinds of growth retardation ", " the five kinds of stiffness in infant ", clinical 8 types that are divided into: the low mo(u)ld bottom half of spasm type, athetosis type, tetanic type, ataxia type, the type that trembles, muscular tension, mixed type, can't the branch type.
At present cerebral palsy is not had special therapeutic method, with the medicine control, all the other symptoms mostly are anti symptom treatment during except that epilepsy.Should carry out the business initiatives, education and training of intelligence, psychology in early days.
Cardiovascular and cerebrovascular disease is cardiovascular and cerebrovascular disease general designation.Change along with growth in the living standard and rhythm of life, " three-hypers disease " (being hypertension, hyperglycemia and hyperlipidemia) that is called as " affluenza ", hypertensive old people uses depressor to be worthy of careful study, principle is arranged, selection for old depressor, with advancing age, the hypertension prevalence increases gradually.Show about 70% to suffer from hypertension, hyperglycemia or hyperlipidemia among the old people more than 60 years old according to Ministry of Public Health statistics in 2010.
At present, also not especially effectively medicine can treat cerebrovascular disease, mainly prevent by approach such as rational meals, an amount of motion, scientific life style.
Summary of the invention
The purpose of this invention is to provide a kind of medicine for the treatment of cardiovascular and cerebrovascular vessel, cerebral palsy.
Medicine of the present invention is that crude drug carries out prescription with Herba Dendrobii, Radix Ophiopogonis, Radix Scrophulariae, the Radix Astragali, Radix Rehmanniae, Rhizoma Dioscoreae, Radix Trichosanthis, Radix Puerariae, Rhizoma Atractylodis, Cortex Phellodendri.
In the prescription, Herba Dendrobii, sweet in the mouth, cold nature.The energy replenishing YIN and removing heat, reinforcing stomach reg fluid; Has certain antipyretic effect; Can promote gastric secretion, aid digestion; The metabolism of enhancing, the anti-ageing effect of waiting for a long time are arranged.Modern medicine study shows that the contained a kind of esters composition of Herba Dendrobii also has blood circulation promoting and blood stasis dispelling, the treatment thromboangiitis obliterans, and cerebral thrombosis and vein form, effects such as arteriosclerotic obliteration.
Radix Ophiopogonis, nature and flavor: sweet; Little hardship; Cold.The effect of tool nourishing YIN and moistening the lung, reinforcing stomach reg fluid, the relieving restlessness that clears away heart-fire; Cure mainly: dryness of the lung dry cough; Lung abscess; Deficiency of YIN chronic cough; Tianjin wound is thirsty; Quench one's thirst; Vexed insomnia; Have sore throat; The dryness of the intestine constipation; Heat in blood is told nosebleed.The traditional Chinese medical science discovers, Radix Ophiopogonis to allevating angina pectoris, uncomfortable in chest certain effect arranged all.Modern medicine study shows; infraction back myocardial nutritional flow amount is increased, and the myocardial cell of hypoxic-ischemic comparatively fast obtains to repair and protection, causes the release of myocardium cGMP and cAMP to reduce; thereby the content in the reduction blood plasma, and both are restored balance by ratio.
Radix Scrophulariae, bitter in the mouth is salty, cold nature; Nontoxic.Attending effectiveness: removing heat from blood YIN nourishing, eliminating fire and detoxication, fever excessive thirst, spontaneous sweating, constipation, haematemesis nose bleeding, pharyngolaryngitis, pulmonary tuberculosis.Be used for consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, Tianjin and hinder constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.Modern medicine study shows; it is as follows that Radix Scrophulariae has certain pharmacological action: 1. the effect of pair cardiovascular system: the Radix Scrophulariae ethanol extraction can obviously increase the extrasomatic rabbit heart coronary flow; increase mouse cardiac muscle 86 rubidium intakes; rabbit experiment myocardial ischemia due to the pituitrin there is protective effect, can also strengthens the mice hypoxia-bearing capability, anesthetized cat is had certain hypotensive effect.In addition, Radix Scrophulariae can also increase the rabbit ear perfusion flow that exsomatizes, and rabbit aorta vasospasm due to potassium chloride and the epinephrine is had certain mitigation.2. central inhibitory action: mice is had calmness, anti-frightened effect.3. antibacterial action: 50% decoct plate dilution method has inhibitory action to staphylococcus aureus.The bright method of Radix Scrophulariae leaf has inhibitory action with the flat board method that burrows to bacillus pyocyaneus.The preserved material tube dilution method has inhibitory action to tinea barbae trichobacteria, microsporum canis.4. other effects: to multiple pathogenic and the non-pathogenic fungus is inhibited.Extractum has slight hypoglycemic activity to rabbit.
The Radix Astragali has another name called Radix Astragali.The medicinal history in existing more than 2000 year so far of the Radix Astragali, modern study, the Radix Astragali contain various trace elements such as Saponin, sucrose, polysaccharide, several amino acids, folic acid and selenium, zinc, copper.The enhancing human body immunity function arranged, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Radix Rehmanniae, nature and flavor sweetness and bitterness, cold, nontoxic, go into the heart, liver, kidney channel.Have heat clearing away, promote the production of body fluid, YIN nourishing, the effect that nourishes blood.Cure mainly: fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon is hindered constipation.Modern medicine study shows: the Radix Astragali can effectively strengthen body immunity, and endocrine is had certain regulatory function.
Rhizoma Dioscoreae, (root) is sweet, warm, flat, nontoxic.Modern medicine study proves that Rhizoma Dioscoreae has invigorating spleen and reinforcing stomach, aid digestion, kidney nourishing and replenishing vital essence, lung benefiting cough-relieving, blood sugar lowering, the effect of life lengthening.
Radix Trichosanthis, tool clearing away heat-fire, promoting the production of body fluid to quench thirst, the effect of evacuation of pus detumescence.Cure mainly: control calentura thirsty, quench one's thirst, dryness of the lung hemoptysis, carbuncle, hemorrhoid flaccidity.For the treatment diabetes, commonly used it and drugs for nourishing yin are used, to reach the effect for the treatment of both the principal and secondary aspects of a disease.
Radix Puerariae, cool in nature, gas is put down, sweet in the mouth, tool heat clearing away, pathogenic fire reducing, all effects of toxin expelling.Modern medicine study shows: the isoflavonoid puerarin in the Radix Puerariae has certain curative effect to hypertension, hyperlipidemia, hyperglycemia and cardiovascular and cerebrovascular disease.
Rhizoma Atractylodis, hot, bitter, temperature.Return spleen, stomach, Liver Channel.Tool is drying damp and strengthening spleen, expelling wind and cold, and an effect makes eye bright.Be used for distension and fullness in the abdomen, the edema of having loose bowels, the beriberi flaccidity is preesed, rheumatic arthralgia, anemofrigid cold, nyctalopia.Have adjust gastrointestinal motility function, antiulcer, protect the liver, antibacterial etc.
Cortex Phellodendri, nature and flavor, hardship, cold.Return kidney, bladder, large intestine channel.Function with cure mainly: be used for damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, the hectic fever due to YIN-deficiency consumptive fever, night sweat, the seminal emission, sore swollen toxin, eczema pruritus.Modern medicine study shows, that Cortex Phellodendri has is antibiotic, antitussive, hypotensive effect, and the function of human immunity improves in office.
The Rhizoma Anemarrhenae, property of medicine hardship, sweet, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, the effect of promoting the production of body fluid and moisturizing.The external treatment fever caused by exogenous pathogenic factors, the hyperpyrexia excessive thirst, the treatment by oral administration of medicines cough due to lung-heat, gastric heat is quenched one's thirst.
Medicine of the present invention makes the effect of above-mentioned each medicine produce synergism, plays the function of its YIN nourishing detoxifcation, the toxin expelling of invigorating blood circulation altogether, thereby reaches treatment of diseases such as cerebral palsy of children, the obstructions of middle-aged and elderly people cardiovascular and cerebrovascular vessel.
Clinical practice proves that medicine of the present invention has the following function that cures mainly:
(1) cerebral palsy of children had good therapeutical effect
Be clinical data statistics below to the cerebral palsy of children patient:
Case is selected: typical cerebral palsy of children 15 examples, the age was at 3～6 years old.
Therapeutic Method: medicated wine medicine of the present invention.2 times on the one, a 20～30ml, course of treatment of two weeks, one to two course of treatment of state of an illness the lighter, the heavier person of the state of an illness needs three to four courses of treatment.
Therapeutic outcome: 12 routine patient's recoveries from illness.2 routine patients' symptom makes moderate progress, and 1 routine patient does not have the obvious treatment effect because adhere to medication.
Add up above-mentioned clinical data, medicine of the present invention reaches 80% to the cure rate of cerebral palsy of children, and effective percentage is 94%.
(2) obstruction has good therapeutical effect to the middle-aged and elderly people cardiovascular and cerebrovascular vessel
Be the clinical data statistics of cardiovascular and cerebrovascular vessel being stopped up the patient below:
Case is selected: typical cardio-cerebral vascular disease patient 20 examples, the age was at 50～75 years old.
Therapeutic Method: medicated wine medicine of the present invention.3 times on the one, a 50～100ml, 10 days courses of treatment, one to two course of treatment of state of an illness the lighter, the heavier person of the state of an illness needs three to four courses of treatment.
Therapeutic outcome: 12 routine patient's recoveries from illness.8 routine patients' symptom makes moderate progress.Effective percentage is 100%
In addition, a large amount of clinical data reality, medicine of the present invention can effectively improve immune function of human body.
Through a large amount of experiments, each crude drug of the present invention all has tangible curative effect in following ratio range:
20～40 parts of Herba Dendrobiis, 15～35 parts of Radix Ophiopogonis, 40～60 parts of Radix Scrophulariae, 50～70 parts of the Radixs Astragali, 90～120 parts of Radix Rehmanniae, 90～120 parts of Rhizoma Dioscoreaes, 10～30 parts of Radix Trichosanthis, 5～25 parts of Radix Puerariaes, 5～25 parts of Rhizoma Atractylodis, 5～25 parts of Cortex Phellodendris.
Optimum ratio is:
25～35 parts of Herba Dendrobiis, 20～30 parts of Radix Ophiopogonis, 45～55 parts of Radix Scrophulariae, 55～65 parts of the Radixs Astragali, 95～110 parts of Radix Rehmanniae, 95～110 parts of Rhizoma Dioscoreaes, 15～20 parts of Radix Trichosanthis, 15～20 parts of Radix Puerariaes, 15～20 parts of Rhizoma Atractylodis, 15～20 parts of Cortex Phellodendris.
Best proportioning is:
30 parts of Herba Dendrobiis, 25 parts of Radix Ophiopogonis, 50 parts of Radix Scrophulariae, 60 parts of the Radixs Astragali, 100 parts of Radix Rehmanniae, 100 parts of Rhizoma Dioscoreaes, 20 parts of Radix Trichosanthis, 15 parts of Radix Puerariaes, 15 parts of Rhizoma Atractylodis, 5 parts of Cortex Phellodendris.
Described crude drug also comprises 10～15 parts the Rhizoma Anemarrhenae, and the best is 10 parts.
Medicine of the present invention can be prepared into the acceptable any preparation of pharmaceutics according to the common process and the adjuvant of pharmaceutics.
The specific embodiment
The preparation of medicated wine
Prescription: in weight portion
30 parts of Herba Dendrobiis, 25 parts of Radix Ophiopogonis, 50 parts of Radix Scrophulariae, 60 parts of the Radixs Astragali, 100 parts of Radix Rehmanniae, 100 parts of Rhizoma Dioscoreaes, 20 parts of Radix Trichosanthis, 15 parts of Radix Puerariaes, 15 parts of Rhizoma Atractylodis, 5 parts of Cortex Phellodendris.
Technology: above-mentioned each crude drug is ground into 50～100 purpose powder, soaked 10～30 days with 30～35 jowar wines of spending.Wherein the consumption of jowar wine is 5～10 times of crude drug gross weight.
Claims (8)
1. medicine for the treatment of cardiovascular and cerebrovascular vessel, cerebral palsy is the preparation that is prepared from by following bulk drugs:
20～40 parts of Herba Dendrobiis, 15～35 parts of Radix Ophiopogonis, 40～60 parts of Radix Scrophulariae, 50～70 parts of the Radixs Astragali, 90～120 parts of Radix Rehmanniae, 90～120 parts of Rhizoma Dioscoreaes, 10～30 parts of Radix Trichosanthis, 5～25 parts of Radix Puerariaes, 5～25 parts of Rhizoma Atractylodis, 5～25 parts of Cortex Phellodendris.
2. treat the medicine of cardiovascular and cerebrovascular vessel, cerebral palsy according to claim 1, it is characterized in that: the weight proportion of described each crude drug is as follows:
25～35 parts of Herba Dendrobiis, 20～30 parts of Radix Ophiopogonis, 45～55 parts of Radix Scrophulariae, 55～65 parts of the Radixs Astragali, 95～110 parts of Radix Rehmanniae, 95～110 parts of Rhizoma Dioscoreaes, 15～20 parts of Radix Trichosanthis, 15～20 parts of Radix Puerariaes, 15～20 parts of Rhizoma Atractylodis, 15～20 parts of Cortex Phellodendris.
3. treat the medicine of cardiovascular and cerebrovascular vessel, cerebral palsy according to claim 1, it is characterized in that: the weight proportion of described each crude drug is as follows:
30 parts of Herba Dendrobiis, 25 parts of Radix Ophiopogonis, 50 parts of Radix Scrophulariae, 60 parts of the Radixs Astragali, 100 parts of Radix Rehmanniae, 100 parts of Rhizoma Dioscoreaes, 20 parts of Radix Trichosanthis, 15 parts of Radix Puerariaes, 15 parts of Rhizoma Atractylodis, 5 parts of Cortex Phellodendris.
4. as the medicine of treatment cardiovascular and cerebrovascular vessel, cerebral palsy as described in the claim 1,2 or 3, it is characterized in that: described crude drug also comprises 10～15 parts the Rhizoma Anemarrhenae.
5. treat the medicine of cardiovascular and cerebrovascular vessel, cerebral palsy according to claim 1, it is characterized in that: common process and adjuvant according to pharmaceutics are prepared into the acceptable any preparation of pharmaceutics.
6. treat the medicine of cardiovascular and cerebrovascular vessel, cerebral palsy according to claim 1, it is characterized in that: described preparation is a medicated wine.
7. as the medicine of treatment cardiovascular and cerebrovascular vessel, cerebral palsy as described in the claim 6, it is characterized in that: the preparation technology of described medicated wine is: above-mentioned each crude drug is ground into 50～100 purpose powder, soaked 10～30 days with the jowar wines of 30～35 degree.
8. as the medicine of treatment cardiovascular and cerebrovascular vessel, cerebral palsy as described in the claim 7, it is characterized in that: the consumption of jowar wine is 5～10 times of crude drug gross weight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2010105520610A CN102000266A (en) | 2010-11-22 | 2010-11-22 | Medicament for treating cardiovascular and cerebrovascular diseases and brain paralysis and preparation method thereof |
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| CN2010105520610A CN102000266A (en) | 2010-11-22 | 2010-11-22 | Medicament for treating cardiovascular and cerebrovascular diseases and brain paralysis and preparation method thereof |
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| CN102000266A true CN102000266A (en) | 2011-04-06 |
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| CN2010105520610A Pending CN102000266A (en) | 2010-11-22 | 2010-11-22 | Medicament for treating cardiovascular and cerebrovascular diseases and brain paralysis and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104906518A (en) * | 2015-07-01 | 2015-09-16 | 李晓莉 | Medicine for treating child cerebral palsy |
| CN106511771A (en) * | 2016-12-17 | 2017-03-22 | 杨翠娜 | Traditional Chinese medicine for treating cerebral palsy |
| CN107929552A (en) * | 2017-11-26 | 2018-04-20 | 杨韶彰 | Treat the Chinese medicine of brain paralysis |
-
2010
- 2010-11-22 CN CN2010105520610A patent/CN102000266A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104906518A (en) * | 2015-07-01 | 2015-09-16 | 李晓莉 | Medicine for treating child cerebral palsy |
| CN106511771A (en) * | 2016-12-17 | 2017-03-22 | 杨翠娜 | Traditional Chinese medicine for treating cerebral palsy |
| CN107929552A (en) * | 2017-11-26 | 2018-04-20 | 杨韶彰 | Treat the Chinese medicine of brain paralysis |
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Application publication date: 20110406 |