CN107837381A - Ointment for treating scald and preparation method thereof - Google Patents

Ointment for treating scald and preparation method thereof Download PDF

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CN107837381A
CN107837381A CN201711322038.0A CN201711322038A CN107837381A CN 107837381 A CN107837381 A CN 107837381A CN 201711322038 A CN201711322038 A CN 201711322038A CN 107837381 A CN107837381 A CN 107837381A
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parts
compound
ointment
filtrate
scald
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朱倩莹
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Abstract

It is used to treat the ointment scalded the invention discloses a kind of, includes the raw material of following parts by weight:45 parts of 15 18 parts of aloe, 78 parts of lavender, 78 parts of dried peppermint leaf, 34 parts of capsicum flesh, 78 parts of ginger, 45 parts of garlic, 34 parts of chilli seed, 10 12 parts of black soya bean, 78 parts of dog oil, 10 15 parts of cockscomb, 78 parts of fish glue, 56 parts of white fungus and egg;The invention discloses a kind of preparation method for being used to treat the ointment of scald, comprise the following steps:First compound, the second compound, the 3rd compound carry out 3 temperature controls and react to obtain concentrate;Capsicum flesh, ginger, garlic and the first filter residue mix to obtain extract solution, and white fungus, cockscomb, fish glue and extract solution mix to obtain sticky cream;Concentrate, sticky cream and egg are stirred and produced.Traditional Chinese medicinal ointment prepared by the present invention can quickly alleviating pain, anti-inflammatory, foreshortened to 89 days simultaneously for the treatment cycles of two degree of wounds, and skin healing effect is good.

Description

Ointment for treating scald and preparation method thereof
Technical field
The present invention relates to pharmaceutical technology field.It is more particularly related to it is a kind of be used for treat scald ointment and Its preparation method.
Background technology
Scald is by aphlogistic high-temp liquid (waste water, deep fat, molten steel), high-temp solid (metal of burning etc.) or high temperature Tissue damage caused by steam, it includes high temperature scald and low temperature scald, general part of degree of scald is once hindered, two degree hinder, And three degree of wounds, wherein, the scald once hindered only damages skin surface, and local mild redness, without blister, pain is obvious, for Its processing can voluntarily recover more after using cold water soak, and the scalds of three degree of wounds are subcutaneous, and fat, muscle, bone has damage, and In ash or bronzing, encase the surface of a wound using the gauze that loses no time for its processing and send doctor to handle in time, two degree of wounds are corium scalds, local Congestion and swelling pain, there is the blister to differ in size, the processing on traditional clinical for two degree of wounds at present has many ripe methods, but together When various drawbacks again be present, for example, first, most traditional processing mode is put for big blister can be punctured into blister edge with sterile needle After water, wrapped up after smearing ointment for treating scald, traditional ointment for treating scald can be in close contact after smearing with skin surface, influence table While surface skin gas permeability, it is right without easy-clear, or in reset procedure that ointment for treating scald can remain in skin surface after drying Originally fragile skin surface causes secondary insult;Secondth, western medicine is scalded based on then more options antibiotic medicine, sometimes also Using the hormone of such as insulin etc, while its therapeutic effect is undesirable, wound healing is slower, and would generally leave scar Trace;Therefore for two degree of scalds, there is provided can quickly alleviating pain, anti-inflammatory, while shorten treatment cycle, slow down the side of scar residual Method is current urgent problem.
The content of the invention
It is an object of the invention to solve at least the above, and provide the advantages of at least will be described later.
It is a still further object of the present invention to provide a kind of ointment for being used to treat scald, the traditional Chinese medicinal ointment of preparation can reach fast Short stopping pain, anti-inflammatory, there are 2 weeks or so (wound healings) of traditional plaster simultaneously for the treatment cycle of two degree of wounds, foreshorten to 8-9 My god, and skin healing effect is good.
It is a still further object of the present invention to provide a kind of preparation method for being used to treat the ointment of scald, chilli seed and black soya bean By way of adding white wine frying, compared to traditional frying, can more a greater amount of its medicinal ingredient of release, simultaneously It is sticked on chilli seed and black soya bean perimeter surface, and then promote later stage extraction effect;Later stage temperature control extraction can be largely On stronger compared to the traditional extracting mode cell membrane for destroying aloe, chilli seed and black soya bean.
In order to realize according to object of the present invention and further advantage, there is provided a kind of ointment for being used to treat scald, Include the raw material of following parts by weight:Aloe 15-18 parts, lavender 7-8 parts, dried peppermint leaf 7-8 parts, capsicum flesh 3-4 parts, ginger 7-8 Part, garlic 4-5 parts, chilli seed 3-4 parts, black soya bean 10-12 parts, dog oil 7-8 parts, cockscomb 10-15 parts, fish glue 7-8 parts, white fungus 5-6 Part and egg 4-5 parts.
A kind of preparation method for being used to treat the ointment of scald is provided, is comprised the following steps:
Stirred Step 1: taking aloe to be placed in after being beaten in dog oil, stand 2-3h at room temperature, obtain the first compound;
Take lavender and dried peppermint leaf to obtain Lavender and Peppermint essential oil with steam distillation respectively, take chilli seed It is placed in after drying in pot, adds chilli seed 0.2-0.3 times of white wine measured of gross mass, is fried with slow fire to white wine wine after doing, continue to fry 20-30min processed, take out and crush, obtain capsicum powder of seeds, capsicum powder of seeds is placed in Lavender, add Lavender The ethanol solution of 2 times of amounts of volume, stands 3-4h, obtains the second compound at room temperature;
Take black soya bean to be placed in after drying in pot, add black soya bean 0.2-0.3 times of white wine measured of gross mass, fried with slow fire to white wine wine After dry, continue frying 20-30min, take out and crush, obtain black soya bean powder, black soya bean powder is placed in Peppermint essential oil, add peppermint essence The ethanol solution of 2 times of amounts of oil volume, stands 3-4h, obtains the 3rd compound at room temperature;
Step 2: the first compound, the second compound and the 3rd compound are respectively placed in sealing container, after sealing Be placed in refrigerator, take out after 3 temperature controls reaction is repeated, filter respectively, obtain the first filtrate and the first filter residue, the second filtrate and Second filter residue and the 3rd filtrate and the 3rd filter residue, the first filtrate, the second filtrate and the 3rd filter residue of half volume are mixed The 4th compound is closed to obtain, the first filtrate of remaining half volume, the second filter residue and the 3rd filtrate are mixed into obtain the 5th mixing Material, it is respectively placed in after the 4th compound and the 5th compound are stood into 1-2h in sealing container, refrigerator is placed in after sealing, is entered repeatedly Taken out after 2 temperature controls of row reaction, filter respectively, obtain the 4th filtrate and the 5th filtrate, concentrate is evaporated under reduced pressure to after mixing, its In, temperature control reaction includes:The temperature of refrigerator is adjusted by being down to -30 DEG C with 10 DEG C/min speed since 10 DEG C and keeping 13-15min, then it is warming up to 10 DEG C with 10 DEG C/min speed and keeps 5-6min, is then heated up with 10 DEG C/min speed To 40 DEG C and keep 13-15min;
Step 3: taking capsicum flesh, ginger, garlic and the first filter residue to be mixed with beating, mixing slurry is obtained, mixing slurry is put into instead Answer in kettle, add mixing 0.3 times of volume ethanol, carry out pressurized treatments after filter, obtain extract solution, take white fungus, cockscomb, fish glue, And after extract solution is well mixed, the water that 5-6 times of white fungus, cockscomb and fish glue gross mass are measured is added, 90-100 DEG C decocts 20-22h, Mashing, continue 90-100 DEG C and decoct under agitation to thick, obtain sticky cream;
Step 4: must stir material after concentrate, sticky cream and egg are stirred, stirring material loads medicinal cupping, Produce the ointment for treating scald
Preferably, it is evaporated under reduced pressure in step 2 and is specially:Control pressure is 30-40kPa, and temperature is 70-80 DEG C, the time For 20-30min.
Preferably, pressurized treatments are specially in step 3:Regulation reactor is forced into 390KPa and keeps 13-15min, Then normal pressure is depressurized to 30KPa/min speed, then adjusts reactor and be forced into 290KPa and keep 13-15min, then Normal pressure is down to 30KPa/min speed, is repeated 2 times.
Preferably, stir process is specially in step 4:It is 500r/min to control rotating speed, forward direction stirring 10min, reversely 10min is stirred, regulation rotating speed is 1000r/min, forward direction stirring 6min, reverse agitating function 6min.
Preferably, stirring material uses 25kHz ultrasonic irradiation 10-12min before medicinal cupping is loaded in step 4, then uses 30kHz ultrasonic irradiation 5-6min.
The present invention comprises at least following beneficial effect:
Firstth, all traditional Chinese medicine ingredients of ointment for being used to treat scald of the invention, can reach quickly alleviating pain, anti-inflammatory, There are 2 weeks or so (wound healings) of traditional plaster simultaneously for the treatment cycle of two degree of wounds, foreshorten to 8-10 days, and skin healing Effect is good, and no scar remains or has less scar residual, extends and smears the time, can continue desalination and remain scar, in meeting Cure diagnosis and treatment based on an overall analysis of the illness and the patient's condition principle;
Secondth, of the invention contains appropriate (phase for treating the ointment capsicum flesh scalded and setting for chilli seed in it It is few compared with capsicum pulp) capsaicine, and vitamin C and unrighted acid are rich in, capsaicine being capable of effective stimulus surface of a wound table The heat receptor in face, a large amount of Peppermint essential oils contained in dried peppermint leaf are capable of the frigidoreceptor on effective stimulus surface of a wound surface, made Skin, which is formed, intersects sense, wakes up skin perception, and then promotes the dermal cell of the surface of a wound/surrounding residual to aloe, lavender, life The drug effect of ginger, garlic, black soya bean, cockscomb, fish glue, white fungus etc. absorbs, the local edema caused by effectively wound is eliminated, strongly to wound While face is sterilized, promote division and proliferation and the self-regeneration of the Skin Cell of itself;
3rd, dog oil, Peppermint essential oil and Lavender in the preparation method for being used to treat the ointment of scald of the invention Alternately temperature control immersion aloe, pepper (parched) seed and frying black soya bean, first, chilli seed and black soya bean be by adding white wine frying Mode, compared to traditional frying, can more a greater amount of its medicinal ingredient of release, while make its stick on chilli seed and Black soya bean perimeter surface, and then promote later stage extraction effect;Secondly, later stage temperature control extraction can be largely compared to traditional The stronger cell membrane for destroying aloe, chilli seed and black soya bean of extracting mode, extracts effective medicinal ingredient;
4th, the use itself of capsicum flesh, chilli seed and dried peppermint leaf can have the function that to counteract each other, in combination with The setting of lavender, effectively alleviate capsicum flesh, chilli seed and dried peppermint leaf unfavorable skin irritatin, breathing thorn to caused by human body Swash, vascular stimulation;
5th, the addition of ethanol and the setting pressurizeed in the preparation process of extract solution, can be more more effective purer Extraction capsicum flesh in capsaicine, ginger, in a large amount of active anti-inflammation components and the first filter residue that contain in garlic it is remaining effectively Active component;White fungus, the setting of cockscomb and fish glue and processing can effectively facilitate division and proliferation Skin Cell creep covering wound It face, can more have the function that the restriction or checking relation in five elements of ring ring, ring ring are mutually auxiliary relative to traditional traditional Chinese medicinal ointment, accelerate surface of a wound recombination time.
Further advantage, target and the feature of the present invention embodies part by following explanation, and part will also be by this The research and practice of invention and be understood by the person skilled in the art.
Embodiment
With reference to embodiment, the present invention is described in further detail, to make those skilled in the art with reference to specification Word can be implemented according to this.
<Embodiment 1>
A kind of ointment for being used to treat scald, include the raw material of following parts by weight:15 parts of aloe, 7 parts of lavender, dried peppermint leaf 7 parts, 3 parts of capsicum flesh, 7 parts of ginger, 4 parts of garlic, 3 parts of chilli seed, 10 parts of black soya bean, dog oil 7 parts, 10 parts of cockscomb, 7 parts of fish glue, silver 4 parts of 5 parts of ear and egg.
<Embodiment 2>
A kind of ointment for being used to treat scald, include the raw material of following parts by weight:18 parts of aloe, 8 parts of lavender, dried peppermint leaf 8 parts, 4 parts of capsicum flesh, 8 parts of ginger, 5 parts of garlic, 4 parts of chilli seed, 12 parts of black soya bean, dog oil 8 parts, 15 parts of cockscomb, 8 parts of fish glue, silver 5 parts of 6 parts of ear and egg.
<Embodiment 3>
A kind of preparation method for being used to treat the ointment of scald, comprises the following steps:
Stirred Step 1: taking aloe to be placed in after being beaten in dog oil, stand 2.5h at room temperature, obtain the first compound;
Take lavender and dried peppermint leaf to obtain Lavender and Peppermint essential oil with steam distillation respectively, take chilli seed It is placed in after drying in pot, adds the white wine of 0.25 times of amount of chilli seed gross mass, is fried with slow fire to white wine wine after doing, continue frying 25min, take out and crush, obtain capsicum powder of seeds, capsicum powder of seeds is placed in Lavender, add Lavender volume 2 The ethanol solution of amount again, stands 3.5h, obtains the second compound at room temperature;
Take black soya bean to be placed in after drying in pot, add the white wine of 0.25 times of amount of black soya bean gross mass, fried to white wine wine and done with slow fire Afterwards, continue frying 25min, take out and crush, obtain black soya bean powder, black soya bean powder is placed in Peppermint essential oil, add peppermint essence oil body The ethanol solution of 2 times of amounts of product, stands 3.5h, obtains the 3rd compound at room temperature;
Step 2: the first compound, the second compound and the 3rd compound are respectively placed in sealing container, after sealing Be placed in refrigerator, take out after 3 temperature controls reaction is repeated, filter respectively, obtain the first filtrate and the first filter residue, the second filtrate and Second filter residue and the 3rd filtrate and the 3rd filter residue, the first filtrate, the second filtrate and the 3rd filter residue of half volume are mixed The 4th compound is closed to obtain, the first filtrate of remaining half volume, the second filter residue and the 3rd filtrate are mixed into obtain the 5th mixing Material, it is respectively placed in after the 4th compound and the 5th compound are stood into 1.5h in sealing container, refrigerator is placed in after sealing, is entered repeatedly Taken out after 2 temperature controls of row reaction, filter respectively, obtain the 4th filtrate and the 5th filtrate, be evaporated under reduced pressure after mixing, be evaporated under reduced pressure specific For:Control pressure is 35kPa, and temperature is 75 DEG C, time 25min, obtains concentrate, wherein, temperature control reaction includes:Regulation The temperature of refrigerator is by being down to -30 DEG C with 10 DEG C/min speed since 10 DEG C and keeping 14min, then with 10 DEG C/min speed It is warming up to 10 DEG C and keeps 5.5min, is then warming up to 40 DEG C with 10 DEG C/min speed and keeps 14min;
Step 3: taking capsicum flesh, ginger, garlic and the first filter residue to be mixed with beating, mixing slurry is obtained, mixing slurry is put into instead Answer in kettle, add mixing 0.3 times of volume ethanol, carry out pressurized treatments after filter, obtain extract solution, take white fungus, cockscomb, fish glue, And after extract solution is well mixed, adds white fungus, the water of 5.5 times of amounts of cockscomb and fish glue gross mass, 95 DEG C of decoction 21h, be beaten, after Continuous 95 DEG C decoct to thick under agitation, obtain sticky cream, wherein, pressurized treatments are specially:Regulation reactor is forced into 390KPa simultaneously keeps 14min, is then depressurized to normal pressure with 30KPa/min speed, then adjusts reactor and is forced into 290KPa And 14min is kept, normal pressure is then down to 30KPa/min speed, is repeated 2 times;
Step 4: must stir material after concentrate, sticky cream and egg are stirred, stirring material loads medicinal cupping, The ointment for treating scald is produced, wherein, stir process is specially:It is 500r/min to control rotating speed, forward direction stirring 10min, Reverse agitating function 10min, regulation rotating speed are 1000r/min, forward direction stirring 6min, reverse agitating function 6min;Stirring material is loading medicinal cupping The preceding ultrasonic irradiation 11min with 25kHz, then with 30kHz ultrasonic irradiation 5.5min;
Wherein, in above-mentioned preparation method, by weight, each parts by weight of raw materials is as follows:It is 15 parts of aloe, 7 parts of lavender, thin 7 parts of lotus leaf, 3 parts of capsicum flesh, 7 parts of ginger, 4 parts of garlic, 3 parts of chilli seed, 10 parts of black soya bean, 7 parts of dog oil, 10 parts of cockscomb, fish glue 7 4 parts of part, 5 parts of white fungus and egg.
<Embodiment 4>
A kind of preparation method for being used to treat the ointment of scald, comprises the following steps:
Stirred Step 1: taking aloe to be placed in after being beaten in dog oil, stand 3h at room temperature, obtain the first compound;
Take lavender and dried peppermint leaf to obtain Lavender and Peppermint essential oil with steam distillation respectively, take chilli seed It is placed in after drying in pot, adds the white wine of 0.3 times of amount of chilli seed gross mass, is fried with slow fire to white wine wine after doing, continue frying 30min, take out and crush, obtain capsicum powder of seeds, capsicum powder of seeds is placed in Lavender, add Lavender volume 2 The ethanol solution of amount again, stands 4h, obtains the second compound at room temperature;
Take black soya bean to be placed in after drying in pot, add the white wine of 0.3 times of amount of black soya bean gross mass, fried to white wine wine and done with slow fire Afterwards, continue frying 30min, take out and crush, obtain black soya bean powder, black soya bean powder is placed in Peppermint essential oil, add peppermint essence oil body The ethanol solution of 2 times of amounts of product, stands 4h, obtains the 3rd compound at room temperature;
Step 2: the first compound, the second compound and the 3rd compound are respectively placed in sealing container, after sealing Be placed in refrigerator, take out after 3 temperature controls reaction is repeated, filter respectively, obtain the first filtrate and the first filter residue, the second filtrate and Second filter residue and the 3rd filtrate and the 3rd filter residue, the first filtrate, the second filtrate and the 3rd filter residue of half volume are mixed The 4th compound is closed to obtain, the first filtrate of remaining half volume, the second filter residue and the 3rd filtrate are mixed into obtain the 5th mixing Material, it is respectively placed in after the 4th compound and the 5th compound are stood into 2h in sealing container, refrigerator is placed in after sealing, is repeated Taken out after 2 temperature controls reaction, filter respectively, obtain the 4th filtrate and the 5th filtrate, be evaporated under reduced pressure after mixing, be evaporated under reduced pressure specific For:Control pressure is 40kPa, and temperature is 70 DEG C, time 20min, obtains concentrate, wherein, temperature control reaction includes:Regulation The temperature of refrigerator is by being down to -30 DEG C with 10 DEG C/min speed since 10 DEG C and keeping 15min, then with 10 DEG C/min speed It is warming up to 10 DEG C and keeps 6min, is then warming up to 40 DEG C with 10 DEG C/min speed and keeps 15min;
Step 3: taking capsicum flesh, ginger, garlic and the first filter residue to be mixed with beating, mixing slurry is obtained, mixing slurry is put into instead Answer in kettle, add mixing 0.3 times of volume ethanol, carry out pressurized treatments after filter, obtain extract solution, take white fungus, cockscomb, fish glue, And after extract solution is well mixed, white fungus, the water of 6 times of amounts of cockscomb and fish glue gross mass are added, 90 DEG C of decoction 22h, is beaten, continues 100 DEG C decoct to thick under agitation, obtain sticky cream, wherein, pressurized treatments are specially:Regulation reactor is forced into 390KPa And 15min is kept, normal pressure is then depressurized to 30KPa/min speed, reactor is then adjusted and is forced into 290KPa and keeps 13min, normal pressure is then down to 30KPa/min speed, be repeated 2 times;
Step 4: must stir material after concentrate, sticky cream and egg are stirred, stirring material loads medicinal cupping, The ointment for treating scald is produced, wherein, stir process is specially:It is 500r/min to control rotating speed, forward direction stirring 10min, Reverse agitating function 10min, regulation rotating speed are 1000r/min, forward direction stirring 6min, reverse agitating function 6min;Stirring material is loading medicinal cupping The preceding ultrasonic irradiation 12min with 25kHz, then with 30kHz ultrasonic irradiation 5min;
Wherein, in above-mentioned preparation method, by weight, each parts by weight of raw materials is as follows:It is 18 parts of aloe, 8 parts of lavender, thin 8 parts of lotus leaf, 4 parts of capsicum flesh, 8 parts of ginger, 5 parts of garlic, 4 parts of chilli seed, 12 parts of black soya bean, 8 parts of dog oil, 15 parts of cockscomb, fish glue 8 5 parts of part, 6 parts of white fungus and egg.
<Contrast experiment 1>
The ointment for treating burn and scald of pharmacy's purchase, primary raw material:Badger fat, garden burnet, borneol, wool grease, beeswax, cream jasmin france, Albolene.
<Contrast experiment 2>
Include the raw material of following parts by weight:15 parts of aloe, 7 parts of ginger, 4 parts of garlic, 10 parts of black soya bean, dog oily 7 parts, cockscomb 10 Part, 7 parts of fish glue, 5 parts of white fungus and 4 parts of egg;
Preparation method is:
S1, take aloe to be placed in dog oil and stir after being beaten, stand 2-3h at room temperature, be placed in sealing container, seal After be placed in refrigerator, be repeated 3 temperature controls reaction (method is with embodiment 3) take out afterwards, filter to get filtrate and filter residue, filtrate subtract Pressure distillation (method is with embodiment 3), obtains concentrate;
S2, take ginger, garlic, black soya bean and filter residue to be mixed with beating, obtain mixing slurry, mixing slurry is put into reactor, add The ethanol of 0.3 times of volume is mixed, pressurized treatments (method is with embodiment 3) is carried out and filters afterwards, obtain extract solution, take white fungus, cockscomb, fish After glue and extract solution are well mixed, white fungus, the water of 5.5 times of amounts of cockscomb and fish glue gross mass are added, 95 DEG C of decoction 21h, is beaten, Continue 95 DEG C to decoct under agitation to thick, obtain sticky cream;
S3, material must be stirred after being stirred concentrate, sticky cream and egg, stirring material loads medicinal cupping, i.e., , wherein, stir process is the same as embodiment 3;Stirring material uses 25kHz ultrasonic irradiation 11min before medicinal cupping is loaded, and then uses 30kHz ultrasonic irradiation 5.5min.
<Contrast experiment 3>
Include the raw material of following parts by weight:15 parts of aloe, 7 parts of ginger, 4 parts of garlic, 10 parts of black soya bean, dog oily 7 parts and egg Clear 4 parts;
Preparation method is:
S1, take aloe to be placed in dog oil and stir after being beaten, stand 2-3h at room temperature, be placed in sealing container, seal After be placed in refrigerator, be repeated 3 temperature controls reaction (method is with embodiment 3) take out afterwards, filter to get filtrate and filter residue, filtrate subtract Pressure distillation (method is with embodiment 3), obtains the first concentrate;
S2, take ginger, garlic, black soya bean and filter residue to be mixed with beating, obtain mixing slurry, mixing slurry is put into reactor, add The ethanol of 0.3 times of volume is mixed, pressurized treatments (method is with embodiment 3) is carried out and filters afterwards, obtains extract solution, after extract solution concentration, Obtain the second concentrate;
S3, material must be stirred after being stirred the first concentrate, the second concentrate and egg, stirring material loads Medicinal cupping, produce, wherein, stir process is the same as embodiment 3;Stirring material uses 25kHz ultrasonic irradiation 11min before medicinal cupping is loaded, Then 30kHz ultrasonic irradiation 5.5min is used.
Experiment 1
Deferring to《Protection animal world clause》On the basis of, body weight is taken in 200g-220g male rat 60, with Machine is divided into 6 groups, every group 10, is defined as A groups, B groups, C groups, D groups, E groups and F groups, respectively by the back part shaving of rat, does After anaesthetic treatment, rat two level scalding model is made to B groups, C groups, D groups, E groups and F groups, is specially:It is 4cm's by base diameter The built-in 90 DEG C of hot water of hollow metal cylinder, scald rat back baring skin 20s;
Wherein, the rat in A groups and B groups with the Iodophor cotton balls sterilization surface of a wound, (find naked corresponding to one every three days by A groups Reveal surface), then covered with salt solution cotton balls wiped clean, gauze, sterile gauze and bandaging;
The ointment for being used to treat scald that C groups are obtained using embodiment 3, concrete operations are:Iodophor cotton balls is used every three days Sterilize the surface of a wound, then with salt solution cotton balls wiped clean, the ointment for being used to treat scald that coating embodiment 3 obtains, after covered with gauze Lid, sterile gauze and bandaging;
D groups use the ointment for treating burn and scald of contrast experiment 1, and concrete operations are:The surface of a wound is sterilized with Iodophor cotton balls every three days, then is used Salt solution cotton balls wiped clean, coat contrast experiment 1 ointment for treating burn and scald, after covered with gauze, sterile gauze and bandaging;;
E groups use the ointment that contrast experiment 2 obtains, and concrete operations are:The surface of a wound is sterilized with Iodophor cotton balls every three days, then is used Salt solution cotton balls wiped clean, coating contrast experiment 2 obtain ointment, after covered with gauze, sterile gauze and bandaging;;
F groups use the ointment that contrast experiment 3 obtains, and concrete operations are:The surface of a wound is sterilized with Iodophor cotton balls every three days, then is used Salt solution cotton balls wiped clean, coating contrast experiment 3 obtain ointment, after covered with gauze, sterile gauze and bandaging;.
Interpretation of result
The therapeutic effect of the 3rd day and the 9th day of each group rat after the treatment is counted, shown in table 1 specific as follows:
Table 1
Experiment 2:
126 scald patients of coprocessing, including steam scald 29, boiling water burn 97, wherein, 105 in 8 days Therapeutic effect is obvious, wound healing, 21 in 10 days treat symptom it is effective, wound healing, its total effective rate reaches 100%;
105 significantly notable cases of therapeutic effect in 8 days
Case 1
Zhao, female, 27 years old, when having a dinner party, boiling water fell scald leg skin in cup, was sterilized and created with Iodophor cotton balls every 2 days Face, then with salt solution cotton balls wiped clean, the ointment for being used to treat scald that coating embodiment 3 obtains, after covered with gauze, it is sterile Gauze and bandaging, stop 3 hours, stick the 2nd day between dressing twice, have no obvious tissue exudates during dressing, stick 4th day, during dressing, see obvious incrustation phenomenon, stick the 8th day, wound healing degree is good, has no obvious scar, dermatoglyph tissue Clearly.
Case 2
Wu, female, 25 years old, boiler factory employee, wound is splashed by hot waste water during working, sterilized and created with Iodophor cotton balls every 2 days Face, then with salt solution cotton balls wiped clean, the ointment for being used to treat scald that coating embodiment 3 obtains, after covered with gauze, it is sterile Gauze and bandaging, stop 3 hours, stick the 2nd day between dressing twice, have no obvious tissue exudates during dressing, stick 4th day, during dressing, see obvious incrustation phenomenon, stick the 8th day, wound healing degree is good, has no obvious scar, dermatoglyph tissue Clearly.
Case 3
Lee, man, 3 years old, father and mother were careless when having a dinner party, and hot water scald arm skin, were sterilized and created with Iodophor cotton balls every 2 days Face, then with salt solution cotton balls wiped clean, the ointment for being used to treat scald that coating embodiment 3 obtains, after covered with gauze, it is sterile Gauze and bandaging, stop 3 hours, stick the 2nd day between dressing twice, have no obvious tissue exudates during dressing, stick 4th day, during dressing, see obvious incrustation phenomenon, stick the 8th day, wound healing degree is good, has no obvious scar, dermatoglyph tissue Clearly.
Although embodiment of the present invention is disclosed as above, it is not restricted in specification and embodiment listed With it can be applied to various suitable the field of the invention completely, can be easily for those skilled in the art Other modification is realized, therefore under the universal limited without departing substantially from claim and equivalency range, it is of the invention and unlimited In specific details and shown here as the embodiment with description.

Claims (6)

1. a kind of ointment for being used to treat scald, it is characterised in that include the raw material of following parts by weight:Aloe 15-18 parts, smoke clothing Careless 7-8 parts, dried peppermint leaf 7-8 parts, capsicum flesh 3-4 parts, ginger 7-8 parts, garlic 4-5 parts, chilli seed 3-4 parts, black soya bean 10-12 parts, Dog oil 7-8 parts, cockscomb 10-15 parts, fish glue 7-8 parts, white fungus 5-6 parts and egg 4-5 parts.
2. a kind of preparation method as claimed in claim 1 for being used to treat the ointment of scald, it is characterised in that including following step Suddenly:
Stirred Step 1: taking aloe to be placed in after being beaten in dog oil, stand 2-3h at room temperature, obtain the first compound;
Take lavender and dried peppermint leaf to obtain Lavender and Peppermint essential oil with steam distillation respectively, take chilli seed to dry After be placed in pot, add chilli seed 0.2-0.3 times of white wine measured of gross mass, with slow fire fry to white wine wine it is dry after, continue frying 20- 30min, take out and crush, obtain capsicum powder of seeds, capsicum powder of seeds is placed in Lavender, add Lavender volume 2 The ethanol solution of amount again, stands 3-4h, obtains the second compound at room temperature;
Take black soya bean to be placed in after drying in pot, add black soya bean 0.2-0.3 times of white wine measured of gross mass, fried to white wine wine and done with slow fire Afterwards, continue frying 20-30min, take out and crush, obtain black soya bean powder, black soya bean powder is placed in Peppermint essential oil, add Peppermint essential oil The ethanol solution of 2 times of amounts of volume, stands 3-4h, obtains the 3rd compound at room temperature;
Step 2: the first compound, the second compound and the 3rd compound are respectively placed in sealing container, it is placed in after sealing In refrigerator, taken out after 3 temperature controls reaction is repeated, filter respectively, obtain the first filtrate and the first filter residue, the second filtrate and second Filter residue and the 3rd filtrate and the 3rd filter residue, the first filtrate, the second filtrate and the 3rd filter residue of half volume are mixed 4th compound, the first filtrate of remaining half volume, the second filter residue and the 3rd filtrate are mixed into obtain the 5th compound, It is respectively placed in after 4th compound and the 5th compound are stood into 1-2h in sealing container, refrigerator is placed in after sealing, is repeated 2 Taken out after secondary temperature control reaction, filter respectively, obtain the 4th filtrate and the 5th filtrate, concentrate is evaporated under reduced pressure to after mixing, wherein, one Secondary temperature control reaction includes:The temperature of refrigerator is adjusted by being down to -30 DEG C with 10 DEG C/min speed since 10 DEG C and keeping 13- 15min, then it is warming up to 10 DEG C with 10 DEG C/min speed and keeps 5-6min, be then warming up to 40 with 10 DEG C/min speed DEG C and keep 13-15min;
Step 3: taking capsicum flesh, ginger, garlic and the first filter residue to be mixed with beating, mixing slurry is obtained, mixing slurry is put into reactor In, the ethanol of 0.3 times of volume of mixing is added, is filtered after carrying out pressurized treatments, is obtained extract solution, take white fungus, cockscomb, fish glue and carry After taking liquid well mixed, the water that 5-6 times of white fungus, cockscomb and fish glue gross mass are measured is added, 90-100 DEG C of decoction 20-22h, is beaten, Continue 90-100 DEG C to decoct under agitation to thick, obtain sticky cream;
Step 4: must stir material after concentrate, sticky cream and egg are stirred, stirring material loads medicinal cupping, produces For treating the ointment of scald.
3. the preparation method as claimed in claim 2 for being used to treat the ointment of scald, it is characterised in that depressurize and steam in step 2 Evaporate specially:Control pressure is 30-40kPa, and temperature is 70-80 DEG C, time 20-30min.
4. the preparation method as claimed in claim 2 for being used to treat the ointment of scald, it is characterised in that in step 3 at pressurization Reason is specially:Regulation reactor is forced into 390KPa and keeps 13-15min, is then depressurized to often with 30KPa/min speed Pressure, then adjust reactor and be forced into 290KPa and keep 13-15min, normal pressure is then down to 30KPa/min speed, instead Carry out 2 times again.
5. the preparation method as claimed in claim 2 for being used to treat the ointment of scald, it is characterised in that in step 4 at stirring Reason is specially:It is 500r/min to control rotating speed, and forward direction stirring 10min, reverse agitating function 10min, regulation rotating speed is 1000r/min, Forward direction stirring 6min, reverse agitating function 6min.
6. the preparation method as claimed in claim 5 for being used to treat the ointment of scald, it is characterised in that material is stirred in step 4 25kHz ultrasonic irradiation 10-12min is used before medicinal cupping is loaded, then with 30kHz ultrasonic irradiation 5-6min.
CN201711322038.0A 2017-12-12 2017-12-12 Ointment for treating scald and preparation method thereof Pending CN107837381A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110841053A (en) * 2019-12-31 2020-02-28 高加喜 Medicine for treating scald and its preparing method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7235265B2 (en) * 2005-10-31 2007-06-26 Ross Rosen Herbal skin formulation
CN103405744A (en) * 2013-08-27 2013-11-27 杨昌标 Plaster for treating scalds and burns and preparation method thereof
CN104873723A (en) * 2015-05-27 2015-09-02 闭炳春 Cinnamon oil containing burn medicine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7235265B2 (en) * 2005-10-31 2007-06-26 Ross Rosen Herbal skin formulation
CN103405744A (en) * 2013-08-27 2013-11-27 杨昌标 Plaster for treating scalds and burns and preparation method thereof
CN104873723A (en) * 2015-05-27 2015-09-02 闭炳春 Cinnamon oil containing burn medicine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110841053A (en) * 2019-12-31 2020-02-28 高加喜 Medicine for treating scald and its preparing method

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