CN106619894A - Traditional Chinese medicine spraying preparation for treating burns and scalds and preparation method thereof - Google Patents

Traditional Chinese medicine spraying preparation for treating burns and scalds and preparation method thereof Download PDF

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Publication number
CN106619894A
CN106619894A CN201611166854.2A CN201611166854A CN106619894A CN 106619894 A CN106619894 A CN 106619894A CN 201611166854 A CN201611166854 A CN 201611166854A CN 106619894 A CN106619894 A CN 106619894A
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parts
scald
spray
burn
preparation
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秦敬华
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dispersion Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention provides a traditional Chinese medicine spraying preparation for treating burns and scalds. The traditional Chinese medicine spraying preparation comprises a medicine spraying preparation; the medicine spraying preparation is prepared from the following medicines in parts by weight: 7 to 13 parts of rhizoma coptidis, 17 to 23 parts of radix et rhizoma rhei, 28 to 32 parts of radix sanguisorbae, 16 to 24 parts of rhizoma polygoni cuspidati and 17 to 23 parts of Chinese gall. The traditional Chinese medicine spraying preparation is mainly applicable to first-degree, second-degree or third-degree burns and scalds and realizes the beneficial effects of rapidness, effectiveness, no scars and the like in a burn and scald treatment process.

Description

It is a kind of to treat Traditional Chinese medicinal spray of burn and scald and preparation method thereof
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to the Chinese medicine for the treatment of burn and scald, more particularly to one kind are treated burning and scalded Traditional Chinese medicinal spray of wound and preparation method thereof.
Background technology
The weight at the order of severity of burn and scald position, size and burn and scald mainly according to burn and scald judging, It is generally divided into three degree:1. I degree of burn and scald:Only injure epidermal area, injured rubefaction, swelling, scorching hot pain, but anhydrous bubble out It is existing;2. II degree of burn and scald:Skin corium is injured, local is red and swollen, heating, hurt like hell has obvious bubble;3. III degree of burn and scald:Entirely Layer skin all comes to harm including the fat below skin, bone and muscle, and skin is burned black, necrosis, injures nerve.
At present the therapeutic modality of burn and scald includes having an intravenous drip and two kinds of external used medicine, and treatment of having an intravenous drip is commonly found in III degree of burning Scald, need the wounded to be in hospital partner treatment, treatment cycle is long, and for I degree or II degree of burn and scald, usual the wounded can select external application Drug therapy, not affect normal Working Life.The external used medicine species of burn and scald is various, mainly plays anti-inflammatory, pain relieving, life Flesh is acted on, and formulation mostly is pulvis, paste.Pulvis or paste are due to the limitation of formulation itself, one side medication inconvenience, each medication When need to clean the residual drug of last time, increase pain to the wounded, and pulvis or paste become easily infected by clothing, be exposed to skin table Face also affects attractive in appearance, and the assimilation effect of another aspect pulvis or paste is bad, and first the skin at burn and scald inherently receives damage Wound, absorbability weakens, and the active ingredient in pulvis or paste receives the restriction of formulation and is difficult to be absorbed by the skin, therapeutic effect Difference.
In order to overcome the defect of above-mentioned burn and scald treatment method, occur many sprays for burn and scald now, spray is first It is first easy to use, secondly drug ingedient is dissolved in hydrojet, the good absorbing effect of skin.For example Patent No. CN1911398 Patent of invention disclose middle medicine spray and the preparation method that a kind of corium burn and scald restores, it is by the garden burnet, bletilla striata, big Huang, gypsum rubrum, six kinds of raw material compositions of quick lime and tea oil, its production method is to grind above-mentioned raw materials medicine, then by weight Amount proportioning is placed in container and is added water to cook in 1: 20 ratio, and after atmospheric boiling after 15 ~ 30 minutes, then filter and remove residue, mixes After quick lime is dissolved, filter and remove residue finally mixes tea oil and is decocted, 3 ~ 5 minutes after atmospheric boiling,.The invention Patent is although easy to use, and therapeutic effect is good, but for burn and scald treats the wound at initial stage, after spray sprinkling, to avoid sense Dye still needs to health care professional carries out sterile dressing, is not suitable for the wounded oneself use at home, for burn and scald treats latter stage Wound, after spray sprinkling, although do not need health care professional to carry out sterile dressing, but wound is exposed among air, empty Bacterium, dust among gas etc. are infected with wound site, easily cause superinfection, affect wound healing, and the several of scar are stayed in increase Rate.
The content of the invention
The present invention still needs to wrapping using after, should not use at home wait defect for treating burn and scald spray in prior art, Offer is a kind of to treat Traditional Chinese medicinal spray of burn and scald and preparation method thereof.
The present invention is adopted the following technical scheme that:
A kind of Traditional Chinese medicinal spray for treating burn and scald, including medicine spray, the medicine spray is made up of the medicine of following weight portion:
7 ~ 13 parts of the coptis, 17 ~ 23 parts of rheum officinale, 28 ~ 32 parts of garden burnet, 16 ~ 24 parts of giant knotweed, 17 ~ 23 parts of Chinese gall.
The preparation method of the Traditional Chinese medicinal spray of above-mentioned treatment burn and scald, the preparation method of the medicine spray is as follows:
(1)Above-mentioned each bulk drug is taken by weight, is added water to and is flooded bulk drug, after 8 ~ 12h of immersion, start to decoct, decocting time For 40min, liquid is taken out after the completion of decoction;
(2)By step(1)Decoct gained liquid to staticly settle 2 ~ 4 days, then take that supernatant is filling to be obtained final product.
Beneficial effects of the present invention are as follows:
The present invention is made up of the medicine for the treatment of burn and scald, after cleaning-sterilizing is processed at burn and scald, spraying medicine spray, and the medicine Spray is made up of the medicine of following weight portion:
The coptis:It is cold in nature, bitter, the thoughts of returning home, spleen, stomach, liver, courage, large intestine channel, with the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating;
Rheum officinale:Cold in nature, bitter returns stomach, large intestine, liver, the spleen channel, with cooling blood and hemostasis, anti-inflammatory and antalgic, removing toxic substances of purging heat, stagnation resolvation latus rectum The effect of;
Garden burnet:It is cold in nature, bitter acid, Return liver, lung, kidney, large intestine channel, the effect of with cooling blood and hemostasis, clearing heat and detoxicating, healing up sore and subduing swelling;
Giant knotweed:Cold nature, mildly bitter flavor, Return liver, courage, lung channel, with the effect of clearing heat and detoxicating, expelling wind and removing dampness, scattered fire removing toxic substances;
Chinese gall:Cold in nature, taste is sour, puckery, return lung, large intestine, kidney channel, the effect of with cooling blood and hemostasis, fall fire of astringing the lung.
Therefore, medicine spray made by above-mentioned each bulk drug can quickly alleviating pain, anti-inflammatory, abatement sepage, promote incrustation, prevent The only generation of scar.And, burn and scald is generally irregular in large area and injury, spray when in use, can be according to burn and scald at Shapes and sizes flexibly spray, just can all covering burn and scald everywhere, be conducive to having given play to therapeutic effect, it is main suitable For I degree, II degree or III degree burn and scald, realize burn and scald treatment it is quick, effective, do not stay the beneficial effects such as scar.
Specific embodiment
In order that the technical purpose of the present invention, technical scheme and beneficial effect are clearer, with reference to specific embodiment Technical scheme is further illustrated.
Embodiment 1
A kind of Traditional Chinese medicinal spray for treating burn and scald, including medicine spray, the medicine spray is made up of the medicine of following weight portion:
7 parts of the coptis, 17 parts of rheum officinale, 28 parts of garden burnet, 16 parts of giant knotweed, 17 parts of Chinese gall;
The preparation method of the medicine spray is as follows:
(1)Above-mentioned each bulk drug being taken by weight, being added water to and is flooded bulk drug, after immersion 8h, start to decoct, decocting time is 40min, takes out liquid after the completion of decoction;
(2)By step(1)Decoct gained liquid to staticly settle 2 ~ 4 days, then take that supernatant is filling to be obtained final product.
The using method of the Traditional Chinese medicinal spray of above-mentioned treatment burn and scald is as follows:
When in use, if any bubble, after bubble belt leather is wiped out completely, cleaning-sterilizing process(If burn and scald area is excessive, need It is auxiliary to use anti-inflammation drugs), then medicine spray is sprayed at burn and scald.
Forbid washing during treatment at burn and scald, while avoiding the aquatic products such as food fish, shrimp, maror, prevent to drink.
Embodiment 2
A kind of Traditional Chinese medicinal spray for treating burn and scald, including medicine spray, the medicine spray is made up of the medicine of following weight portion:
10 parts of the coptis, 20 parts of rheum officinale, 30 parts of garden burnet, 20 parts of giant knotweed, 20 parts of Chinese gall;
The preparation method and using method of medicine spray is with embodiment 1.
Embodiment 3
A kind of Traditional Chinese medicinal spray for treating burn and scald, including medicine spray, the medicine spray is made up of the medicine of following weight portion:
13 parts of the coptis, 23 parts of rheum officinale, 32 parts of garden burnet, 24 parts of giant knotweed, 23 parts of Chinese gall.
The preparation method and using method of medicine spray is with embodiment 1.
In order that wound preferably completely cuts off air to avoid wound from infecting, can be with after spraying medicine spray, spray Film forming spray is spilt, the film forming spray is made up in terms of 100 weight portions of the medicine of following weight portion:
0.5 ~ 1.2 part of shitosan, 3 ~ 8 parts of polyvinylpyrrolidone, 0.5 ~ 1.5 part of acetic acid, balance of medical purified water.
The polyvinylpyrrolidone is PVP K25, PVP K30 or PVP K40.
The preparation method of the film forming spray is as follows:
Take above-mentioned each raw material by weight, first acetic acid added in medical purified water, after stirring evenly, add shitosan, stir to Dissolve and mix, be subsequently adding polyvinylpyrrolidone, stir to dissolving and mixing, obtain final product.
When using, first medicine spray is sprayed at burn and scald after 0 ~ 5min, then sprays film forming spray, it is to be filmed to be afterwards Can.The spraying range of film forming spray can will be covered all around at burn and scald, film forming by waiting a few minutes to be dried after sprinkling, institute's shape Into film fully cover at burn and scald, it is to avoid expose in air at burn and scald, prevented the bacterium in air, dust etc. and make Into infection, and shitosan can be dissolved in weakly acidic aqueous solution, as a kind of macromolecule, can form membrane structure, with killing Bacterium disinfective action, good biocompatibility;Polyvinylpyrrolidone(That is PVP)Any stimulation, biology are not resulted in human body skin Compatibility is good, and is not involved in human metabolism, is safe pharmaceutic adjuvant.Thus, medicine spray and film forming spray coordinate Reach more preferable therapeutic effect.
The test of pesticide effectiveness
Since 2013, the people of burned patient 278 is treated altogether with the Traditional Chinese medicinal spray in the embodiment of the present invention 2, the wherein age exists The patient of less than 20 years old is 97 people, and patient of the age between 20 years old to 35 years old is 135 people, and the age, the patient more than 35 years old was 46 people, the situation of burn and scald has electric injury, boiling water, steam, rolling oil, high-temperature boiler, fire etc..
Method using Traditional Chinese medicinal spray of the present invention is as follows:
If any bubble, after bubble belt leather is wiped out completely, cleaning-sterilizing process(If burn and scald area is excessive, auxiliary anti-inflammatory need to be used Medicine), then medicine spray is sprayed at burn and scald;
Every sprinkling in 2 ~ 5 hours once, fountain height and sprinkling number of times can be increased according to the concrete burn and scald order of severity.
Curative effect judging standard is as follows:
Cure:Heal completely, do not stay scar;
Effectively:Injury is without sepage;
It is invalid:Injury inflammation, pain, persistently produce sepage.
Effect statistics after treatment is as shown in table 1:
Table 1 is counted using the therapeutic effect of medicine spray of the present invention
As shown in Table 1, the present invention is up to 85.9% to the cure rate of I degree or II degree burn and scald, efficient to be more up to 99.9%, and And according to investigation, patient is universal higher to the acceptance of the medicine spray of the present invention, is happy to carrying and uses, and does not spend hospital Wrapping, patient is in voluntarily use, does not interfere with the Working Life of patient.
Model case
Liu, man, 12 years old, when at home parlor is played, accidentally overturns hot-water bottle, and the boiling water of outflow scalds its left foot face, by It is installed with flip-flop on pin, scald is not weighed, is diagnosed as I degree of scald, pain and have sepage at scald, the head of a family send examine in time, at sterilization After reason, it is sprayed at scald using medicine spray of the present invention, pain substantially mitigates after 10min, and medicine spray is taken home In, adhere to using 3 days according to using method, sprayed once every 4 hours within first day, incrustation is started at scald, it is continuing with one Week, incrustation comes off, and the surface of a wound does not leave scar.
Poplar, female 25 years old, when summer eats barbecue outside, encounters barbecue rack accidentally, and leg is scalded, send within second day and examine, skin Fester, be diagnosed as II degree of scald, to carrying out at scald after removing bubble, dead skin, be sprayed on using medicine spray of the present invention At scald, pain is eliminated after 10min, and medicine spray is taken home, and adheres to using 3 days according to using method, is sprayed every 2 hours Spill once, no longer fester at scald, start incrustation, be continuing with two weeks or so, every sprinkling in 5 hours once, incrustation comes off, wound Face does not leave scar.
Chen, female 32 years old, is in and cooks, and during fried fish tartar souce, the high temperature oil for being spilt scalds arm, scalds in many places dispersion, whole Body is lighter, and pain is stronger, is diagnosed as I degree of scald, sprays medicine spray of the present invention, painless after 10min, hereafter presses Adhere to using one week according to using method, once, incrustation comes off, and does not stay scar for sprinkling daily.
Song, man, 50 years old, boiler factory workman operationally slipped accidentally, and back clings to high-temperature boiler, in large area Scald, be diagnosed as II degree of scald, send after examining, the clothing at scald is carried out to wipe out cleaning, spray medicine spray of the present invention, 30min pain reliefs after sprinkling, hereafter adhere to using according to using method, start every sprinkling in 2 hours once, after incrustation, so Afterwards once, incrustation after month completely falls off, and small area scar is left at the only deeper surface of a wound for sprinkling daily.
It is tall certain, man, 43 years old, sesame seed cake stand pedlar when putting sesame seed cake toward in stove, encountered charcoal fire accidentally, and Hand Burns send and examined after examining Break as I degree of burn, after spraying medicine spray 5min of the present invention, no longer feels pain adheres to using three days, and incrustation comes off, Scar is not stayed.
It should be noted last that:Above-described embodiment is merely to illustrate and unrestricted technical scheme, any right Equivalent and the modification without departing from spirit and scope of the invention or local replacement that the present invention is carried out, it all should cover at this Within bright protective scope of the claims.

Claims (2)

1. a kind of Traditional Chinese medicinal spray for treating burn and scald, it is characterised in that including medicine spray, the medicine spray is by following weight The medicine of part is made:
7 ~ 13 parts of the coptis, 17 ~ 23 parts of rheum officinale, 28 ~ 32 parts of garden burnet, 16 ~ 24 parts of giant knotweed, 17 ~ 23 parts of Chinese gall.
2. the preparation method of the Traditional Chinese medicinal spray of burn and scald is treated according to claim 1, it is characterised in that the medicine spray Preparation method it is as follows:
(1)Above-mentioned each bulk drug is taken by weight, is added water to and is flooded bulk drug, after 8 ~ 12h of immersion, start to decoct, decocting time For 40min, liquid is taken out after the completion of decoction;
(2)By step(1)Decoct gained liquid to staticly settle 2 ~ 4 days, then take that supernatant is filling to be obtained final product.
CN201611166854.2A 2016-12-16 2016-12-16 Traditional Chinese medicine spraying preparation for treating burns and scalds and preparation method thereof Pending CN106619894A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
CN201611166854.2A CN106619894A (en) 2016-12-16 2016-12-16 Traditional Chinese medicine spraying preparation for treating burns and scalds and preparation method thereof

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110170006A (en) * 2019-05-31 2019-08-27 麻阳天应苗药发展有限责任公司 A kind of polygonum cuspidate draft anti-inflammatory spray and manufacture craft
CN113679763A (en) * 2021-09-11 2021-11-23 秦喜莲 Gel spray for skin-care lotion

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
周福霞: "复方虎地汤治疗360例烧烫伤临床观察", 《贵阳中医学院学报》 *
谢明祥: "自制速效烧伤喷雾剂治疗烧烫伤85例", 《中国民间疗法》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110170006A (en) * 2019-05-31 2019-08-27 麻阳天应苗药发展有限责任公司 A kind of polygonum cuspidate draft anti-inflammatory spray and manufacture craft
CN113679763A (en) * 2021-09-11 2021-11-23 秦喜莲 Gel spray for skin-care lotion

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