CN109464534B - Composition for preventing and treating burns and scald and preparation method thereof - Google Patents
Composition for preventing and treating burns and scald and preparation method thereof Download PDFInfo
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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Abstract
本发明公开了一种防治烧烫伤的组合物，包括地黄叶和桐油，地黄叶与桐油的质量比为50～150∶75～225。本发明还公开了一种防治烧烫伤的组合物的制备方法，包括如下步骤：S1、将地黄叶进行加热烘焙，然后破碎至粉末状；S2、将经步骤S1处理的地黄叶与桐油混合均匀，即得成品组合物。本发明的防治烧烫伤的组合物起效快、成分简单、能消炎镇痛、去腐生肌、Ⅱ度及以下愈后不留疤，针对Ⅱ度及以下烫伤效果尤佳。本发明的制备方法工艺简单、成本低，且能制备起效快、愈后不留疤、成分简单、能消炎镇痛和去腐生肌的防治烧烫伤的组合物。The invention discloses a composition for preventing and treating burns and scalds. The invention also discloses a preparation method of a composition for preventing and treating burns and scalds, comprising the following steps: S1, heating and baking the leaves of Rehmannia glutinosa, and then crushing them into powder; S2, mixing the leaves of Rehmannia glutinosa treated in step S1 with tung oil evenly , the finished composition is obtained. The composition for preventing and treating burns and scalds of the present invention has quick onset of action, simple ingredients, anti-inflammatory and analgesic, derotation and muscle regeneration, and no scars after recovery of grade II and below, especially for grade II and below scalds. The preparation method of the invention has the advantages of simple process and low cost, and can prepare a composition for preventing and treating burns and scalds, which has quick onset of effect, no scar after healing, simple ingredients, anti-inflammatory, analgesic, saprophytic and muscle-reducing properties.
Description
Technical Field
The invention relates to the field of burns and scalds, in particular to a composition for preventing and treating burns and scalds and a preparation method thereof.
Background
Burn is a common wound and one of the important wounds threatening human health. The traditional Chinese medicine considers that the cause of the burn is fire toxin or heat toxin, and belongs to no internal or external cause. The burns are classified into III degree, II degree and below, which account for most of the burn population, if antibiotics and dressings are frequently used in hospital treatment, even skin grafting is needed, the medical cost is increased, the medical resources are wasted, and the antibiotics have side effects. The external traditional Chinese medicine preparation is one of important treatment measures for small and medium-area burns, but the traditional Chinese medicine preparation has complex components which are generally between 5 and 30, and the effective components of the traditional Chinese medicine are extracted by methods such as an immersion method and the like, so that the preparation process is complicated, the time and labor cost is high, and the cost is also high.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide the composition for preventing and treating the burns and scalds, which has the advantages of quick response, simple components, capability of diminishing inflammation, relieving pain, removing necrotic tissue and promoting granulation, and no scar after healing at the temperature of II or below, and has excellent effect on scalds at the temperature of II or below. The invention also provides a preparation method of the composition for preventing and treating burns and scalds, which has simple process and low cost, can quickly take effect, does not leave scars after healing, has simple components, can diminish inflammation, relieve pain, remove necrotic tissue and promote granulation.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows:
the composition for preventing and treating burns and scalds comprises the effective components of rehmannia leaves and tung oil, wherein the mass ratio of the rehmannia leaves to the tung oil is 50-150: 75-225.
Preferably, the mass ratio of the rehmannia leaves to the tung oil is 50-100: 65-120.
Preferably, the mass ratio of the rehmannia root leaves to the tung oil is 50: 52.5.
The composition for preventing and treating burns and scalds is preferably applied externally.
Preferably, the rehmannia leaves are wild rehmannia leaves.
As a general inventive concept, the invention also provides a preparation method of the composition for preventing and treating burns and scalds, which comprises the following steps:
s1, heating and baking the rehmannia leaves, crushing the rehmannia leaves into powder, and standing and cooling the powder;
s2, uniformly mixing the rehmannia leaves obtained by the step S1 with the tung oil to obtain the finished product composition.
In the preparation method of the composition for preventing and treating burns and scalds, in the step S2, the mass ratio of the rehmannia leaves to the tung oil is preferably 50-150: 75-225.
In the preparation method of the composition for preventing and treating burns and scalds, in the step S1, the heating and baking temperature is preferably 60 to 80 ℃ for 2 to 3 minutes, and then 20 to 30 ℃ for 2 to 4 minutes.
Preferably, before step S1, the preparation method of the composition for preventing and treating burns and scalds further comprises a step of drying the rehmannia leaves; the drying is sun drying or air drying.
In the above method for preparing a composition for preventing and treating burns and scalds, preferably, in step S1, the crushing is performed by twisting or pulverizing.
In the preparation method of the composition for preventing and treating burns and scalds, the finished product composition is preferably stored in a closed container or is prepared for use.
The invention provides a Chinese medicinal preparation for treating burns and scalds, which is prepared from rehmannia leaf and tung oil as active substances and is used for treating local fever, red swelling, blisters and desquamation caused by burns and scalds. The preparation has the functions of clearing away heat and toxic material, diminishing inflammation, relieving pain, eliminating slough and promoting granulation, has quick response, does not leave scars after healing, and has particularly good effect on second-degree and below scalds.
Compared with the prior art, the invention has the advantages that:
1. the composition for preventing and treating burns and scalds has the advantages of quick response, quick pain relieving, difficult scar remaining after healing, simple components, capability of diminishing inflammation, relieving pain, removing necrotic tissue and promoting granulation, and low cost, and is mainly used for treating second-degree and below scalds. The treatment can be carried out at home, the aseptic environment is not needed, the physiological saline and the like are not needed to wash the wound, the wound is directly smeared, the effect is quickly achieved, the treatment time is not delayed, the recovery of a patient is quick, and the adverse reaction is avoided.
2. The composition for preventing and treating burns and scalds can better cling to a wound surface, better affinity to the wound surface, reduce wound surface exudate, form a medicinal scab barrier on the wound surface, prevent infection under the scab and protect the epithelial growth by controlling the proportion of the rehmannia leaf and the tung oil.
3. The composition for preventing and treating burns and scalds at the second degree and below does not need to take other medicines such as antibiotics, analgesics and the like at the same time, avoids adverse reactions caused by the medicines and saves cost.
4. The preparation method of the composition for preventing and treating burns and scalds is simple in process, easy to implement and low in manufacturing cost, and overcomes the defects of time consumption and cost consumption of the existing dipping method.
5. After the composition for preventing and treating burns and scalds is used, the wound does not need to be bound, and the composition can be directly exposed, so that the time, the labor and the cost are saved.
Detailed Description
The present invention will be described in further detail with reference to specific examples. The materials and equipment used in the following examples are commercially available.
The invention relates to a composition for preventing and treating burns and scalds, which comprises active substances of rehmannia leaf and tung oil.
The mass ratio of the rehmannia leaves to the tung oil is 50-150: 75-225. If the rehmannia leaves are more and the tung oil is less, the rehmannia leaves cannot be uniformly smeared on the wound surface, so that the wound surface healing is influenced; if the amount of rehmannia leaves is small, the amount of tung oil is large, the liquid medicine is too thin, the dosage is small, the liquid medicine flows away from the wound surface when being smeared and cannot be attached to the wound surface, the treatment effect cannot be achieved, and if the amount of rehmannia leaves is too small, the good drug effect cannot be achieved. In the composition, the mass ratio of the rehmannia leaf to the tung oil is preferably 50-100: 65-120, and more preferably 50: 52.5.
In the medicine composition, the rehmannia leaves are Scrophulariaceae plants, have the effects of detoxifying and treating sores, are commonly used for treating tinea manuum and tinea pedis, but no research for directly using the rehmannia leaves to treat burns and scalds exists so far; tung oil can be used for treating scabies, ecthyma, scald, chap of chilblain, suppurative inflammation, appendicitis, cholecystitis and tonsillitis, and tung oil alone has poor effect in treating burn and scald.
After the rehmannia leaves and the tung oil in the composition are mixed and interacted, the medicinal components are interacted, so that multiple effects can be exerted, the effects of clearing heat and removing toxicity, diminishing inflammation and easing pain, and removing necrotic tissue and promoting granulation of the whole medicament are improved, the wound healing can be accelerated, the burn and scald are effectively treated, no adverse reaction exists, scars are not easy to leave, and the effect is particularly good for the second-degree and below scalds.
The composition is oil for preventing and treating burn and scald, and is applied by external application.
The rehmannia leaves are preferably wild rehmannia leaves.
The preparation method of the composition for preventing and treating burns and scalds comprises the following steps:
s1, heating and baking the rehmannia leaves, crushing the rehmannia leaves into powder, and standing and cooling the powder;
s2, uniformly mixing the rehmannia leaves obtained by the step S1 with the tung oil to obtain the finished product composition.
The unique pharmaceutical steps adopted by the externally applied medicine can ensure that the two medicines keep the best effective components, and the components exert the effects to the maximum extent and are mutually synergistic.
Compared with other external traditional Chinese medicine preparations for treating burns and scalds, the composition has simple components and relatively low medicine cost, can save medical expenses for patients, and has simple preparation process, time and labor saving and definite curative effect. In addition, the patient does not need to go to a hospital, and can be treated at home, so that the patient is facilitated, meanwhile, the waste of medical resources is reduced, and the medical cost is saved for the country.
In the step S2, the mass ratio of the rehmannia leaves to the tung oil is 50-150: 75-225.
In the step S1, the purpose of the heating baking is to remove moisture, and the heating baking is preferably performed by heating at 60 to 80 ℃ for 2 to 3 minutes, and then at 20 to 30 ℃ for 2 to 4 minutes, and the time required for drying the rehmannia leaves is shorter. In the present invention, the heating mechanism is not limited to the heating mechanism, and the heating mechanism is adopted to obtain a good drying effect.
Before the step S1, it is preferable that the method further comprises a step of drying the rehmannia leaves; the drying is sun drying or air drying. After drying, the preservation time of the rehmannia leaves is favorably prolonged, the baking time can be shortened, and the baking duration can be mastered.
In step S1, the crushing is preferably performed by twisting or pulverizing.
The final composition can be placed in a sealed container such as glass container or plastic container, and has prolonged retention time, and can be directly used for treating burn of patients to obtain therapeutic time. Any container that is not oil-tight may be used if the composition is ready for use.
The composition for preventing and treating burns and scalds can be used for preventing and treating burns and scalds. The application method comprises applying the medicine to the wound surface of burn and scald 3-4 times per day. The medicine is applied in a local moisture-keeping and moistening state, and is preferably not flowed, so that the wound surface is exposed.
Example 1
The invention relates to a composition for preventing and treating burns and scalds, which comprises rehmannia leaf and tung oil, and is specifically prepared from 50g of rehmannia leaf and 52.5g of tung oil.
The preparation method of the composition for preventing and treating burns and scalds comprises the following steps:
s1, sun-drying the traditional Chinese medicines: cleaning rehmannia leaves and drying in the sun;
s2, baking the traditional Chinese medicines: and (3) putting 50g of dried rehmannia leaves into a pot, heating for 2-3 minutes at 60-80 ℃, taking out at 20-30 ℃ for 2-4 minutes, twisting, and standing for cooling. The drier the rehmannia leaves are, the shorter the time is needed;
s3, mixing the materials: mixing 50g of baked rehmannia leaf and 52.5g of tung oil according to the proportion, and directly smearing on the wound surface. If the area is larger, more compositions for preventing and treating burns and scalds are prepared according to the mass ratio.
The using method comprises the following steps: the medicine is applied to the wound surface of the burn and scald 3-4 times a day. The medicine is applied in a local moisture-keeping and moistening state, and is preferably not flowed, so that the wound surface is exposed.
Example 2
The composition for preventing and treating burns and scalds, which is obtained in the embodiment 1, has been used for treating burns and scalds for years, is completely cured, and has a good treatment effect on burns and scalds of II degrees and below. The following are only some clinical cases, and the specific dosage is as follows: the prepared liquid medicine is coated for 3-4 times every day.
1. Wu, a certain woman, 2 years old. Zhang Jiajiu of Zhang Jiajiu city, Cili county, Hunan province, Zhao Jia Zhen shop village. Scald with boiled water, medial side of right thigh. The ointment is used by the fire brigade in county to treat poor effect three days later, at the moment, the whole wound is red and swollen, a plurality of large and small bubbles are soaked, the wound is peeled, the edge is white, the ointment is changed by using the liquid medicine, and the wound is healed after one week without scars.
2. Wu Yi in Wu, male, 5 years old. Zhang Jiajiu city, Cili county, Shamu bridge town, Zhao Jia shop village people, Hunan province. When the patient falls into the heated brick bed during the fire, the right hand burns, and a plurality of large and small water bubbles cause pain and screaming. The pain is relieved after the medicine is applied, and the medicine is cured ten days without scars.
3. Zhuo somer, male, age 42. Zhang Jiajiu city, Cili county, Shamu bridge town, Zhao Jia shop village people, Hunan province. The motorcycle exhaust pipe is scalded, the inner side of the left shank is healed after the medicine is taken for four days, and no scar is left.
4. Somebody on the top of the mother, man, 45 years old. Shanmu bridge town Yanjiata village, Cili county, Zhangjiajie, Hunan province. The motorcycle exhaust pipe is scalded, the left leg and the right leg are not obviously improved after the treatment of one week in a health hospital, and the treatment is introduced by people. The whole affected part of the patient is rotten and red and swollen. After the medicine is applied, the wound is improved after five days, and the wound is healed after the medicine is continuously applied for ten days. No scar is left and the skin is intact.
5. Li A. male, 25 years old. The person who spreads the village, tongjin county, Cili county, Zhangjie, Hunan province. The medial aspect of the upper part of the right thigh is treated one week after the scald. The affected part is red and swollen, the wound is festered, and the right leg can not stand to normally walk. After the medicine is used for eight days, the patient can stand to pick water and heal without scars.
6. Li A certain woman, 65 years old, had both hands burned. Burning mosquitoes in the mosquito net with a kerosene lamp causes the mosquito net to catch fire. A plurality of blisters and broken skins can heal after half a month without scars after the medicine is used.
7. Zhuo somer, male, 7 years old. The people in the bridge town calabash and the village of Sambu, Cili county, Zhang Jiajie, Hunan province. When playing, the patient steps on the fire pile to cause scald on the right instep and the front half end of the toes, and the patient heals six days after the medicine is applied, and no scar is left.
8. Some other than the female. Yuanping village in Cili county, Zhangjie city, Hunan province. More serious scald and larger area. It is said that the treatment is not improved after about half a month in other places, and the treatment is introduced. The medicine is improved twenty days after being used, a small part of the affected part is hyperpigmented when healing, the skin color is different from the normal color, and the follow-up observation is not carried out.
9. Dun somebody, female, 10 years old, Chansha in Hunan province. The right heel is scalded. The medicine has no effect after the earthwork treatment, large and small blisters and red swelling, and can heal for one week without scars after the medicine is used.
10. Zuo somewhere, man, 13 years old, Zhang Jiajie city, Zhao Li county, Hunan province. Scald at the top of the head, desquamation and blisters. After other treatment methods (detailed treatment), the effect is not good, and the medicine can be cured after six days.
11. Zhuo somer, male, 62 years old. Zhao Jia Cui Zi bridge group in Cili county, Zhang Jiajie, Hunan province. And (5) scalding by fire. Redness and swelling, blister and desquamation, which can heal up in sixteen days without scar left.
12. Wu, a certain woman, 11 years old. Zhao Jia Zhou of Cili county, Zhang Jiajie, Hunan province, make up a group of people. Scald the neck with boiling water. Red and swollen, big and small blisters. Fifteen days after the medicine is applied, the skin is healed without obvious scars, and the skin color is only new in the place of about 1 cm.
13. Wu, a certain person, female, 19 years old. Shanxi province in Hunan province. The oil is splashed and scalded when the vegetables are cooked. Bubbling and peeling. The effect is not good after the nano-silver is smeared for four days, and the recovery is realized after the medicine is used for five days, no scar is left, and the skin color is only felt in the place of about 0.5 cm.
14. Some firewood, women, 68 years old. Hunan province Zhang Jiajiu city Samu bridge Town Fengcheng combined people. Scald the breast with boiling water. The skin turns red, blisters, and was painful, but not treated. After two days, the symptoms are aggravated, the complex iodine is applied for three days, the appearance is not obviously changed, and the complex iodine heals up after four days after the medicine is used, and no scar is left.
15. Wu, a certain number of people, male, 14 years old. Zhang Jiajiu city, Cili county, Huinan province Zhao Jia shop village Qinglong gulf group people. The firecrackers on the right hand are exploded and have red and swollen blisters, and can recover without scars seven days after the application of the firecrackers.
Although the present invention has been described with reference to the preferred embodiments, it is not intended to be limited thereto. Those skilled in the art can make numerous possible variations and modifications to the present invention, or modify equivalent embodiments to equivalent variations, without departing from the scope of the invention, using the teachings disclosed above. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical spirit of the present invention should fall within the protection scope of the technical scheme of the present invention, unless the technical spirit of the present invention departs from the content of the technical scheme of the present invention.
Claims (8)
1. The composition for preventing and treating burns and scalds is characterized in that the effective components consist of rehmannia leaves and tung oil, and the mass ratio of the rehmannia leaves to the tung oil is 50-150: 75-225; the rehmannia leaves are wild rehmannia leaves.
2. The composition for preventing and treating burns and scalds according to claim 1, wherein the mass ratio of the rehmannia leaves to the tung oil is 50-100: 65-120.
3. The composition for preventing and treating burns and scalds according to claim 1, wherein the mass ratio of the rehmannia leaf to the tung oil is 50: 52.5.
4. The composition for preventing and treating burns and scalds according to any one of claims 1 to 3, wherein the composition is applied externally.
5. The preparation method of the composition for preventing and treating the burns and the scalds is characterized by comprising the following steps:
s1, heating and baking the rehmannia leaves, and then crushing the rehmannia leaves into powder;
s2, uniformly mixing the rehmannia leaves processed in the step S1 with the tung oil to obtain a finished product composition; the mass ratio of the rehmannia leaves to the tung oil is 50-150: 75-225.
6. The preparation method of the composition for preventing and treating burns and scalds according to claim 5, wherein in the step S1, the heating and baking are performed at 60-80 ℃ for 2-3 minutes and then at 20-30 ℃ for 2-4 minutes;
in the step S1, the crushing is performed by twisting or pulverizing.
7. The method for preparing a composition for preventing and treating burns and scalds according to claim 5 or 6, further comprising the step of drying the rehmannia leaves before the step S1; the drying is sun drying or air drying.
8. The method for preparing the composition for preventing and treating burns and scalds as claimed in claim 5 or 6, wherein the finished composition is stored in a closed container or is prepared for use.
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Non-Patent Citations (3)
| Title |
|---|
| 清热燥湿话黄柏;邓理有;《家庭中医药》;19981231(第01期);第49页 * |
| 自制地榆炭散为主治疗烧伤105例;李卫红，李平;《中国中西医结合杂志》;19971231(第04期);第46页 * |
| 高效液相色谱法测定复方地黄软膏中盐酸小檗碱含量;仲素霞;《中国现代药物应用》;20100625(第12期);第14-15页 * |
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