CN107822980A - One kind is compacted skin composition - Google Patents
One kind is compacted skin composition Download PDFInfo
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- CN107822980A CN107822980A CN201711242106.2A CN201711242106A CN107822980A CN 107822980 A CN107822980 A CN 107822980A CN 201711242106 A CN201711242106 A CN 201711242106A CN 107822980 A CN107822980 A CN 107822980A
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- skin
- composition
- nmf
- antioxidant
- elastatinal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
Compacted skin composition the invention discloses one kind, include the component of antioxidant, NMF, elastatinal, its elastase inhibitor mainly includes one or more of in Gentrin Knotweed P.E, quassia alkaloid, anthocyanidin.Addition antioxidant can reduce skin oxidative damage, delaying skin aging;Adding NMF can not only moisturizing, moreover it is possible to forms water lock barrier in skin surface;Addition elastatinal can effectively compact skin, increase the elasticity of skin;Acted synergistically between composition components, the effect for the skin that preferably compacts can be played, applied in cosmetics, the good skin that compacts of cosmetics, oxidation resistant effect can be assigned.
Description
Technical field
The present invention relates to cosmetic field, and in particular to one kind is compacted skin composition.
Background technology
With advancing age, the gradual aging of skin of face, skin senescence are usually expressed as skin elasticity reduction, skin wrinkle
Line increases, skin roughness increases, skin moisturizing degree weakens etc..And the aging of skin of face be mainly qi and blood it is insufficient and
It is clearly inadequate, ring for prevention skin senescence that moisturizer skin care is merely used caused by the deposition of toxin, in daily life
The factors such as border, sunlight and pressure can all promote the aging of skin, cause skin metabolism to slow down, the collagen and bullet of skin
Property tissue fibers change, and skin becomes more loose, and this image to people causes serious influence.As people live
Horizontal raising, the consciousness of skin care also step up, and skin care increasingly attracts people's attention.
Occur much declaring the products with skin effect of compacting on the market at present, but the effect of publicity exaggerated, it is actual
To no effect or DeGrain, misguide the consumer consumption, or even the product having with the addition of forbidden amphetamine, and can have to skin can not
Inverse damage, therefore, the product for researching and developing a kind of skin that compacts of significant effect are that people are hoped.
The content of the invention
It is an object of the invention to provide a kind of composition for the skin that compacts, act synergistically, have significant anti-between composition
Oxidation, the effect for the skin that compacts, and added in cosmetics, assign cosmetics good skin effect of compacting, flesh can be made
Skin is more flexible.
In order to achieve the above object, the present invention provides following technical scheme:
One kind is compacted skin composition, includes the component of following mass parts:
Antioxidant 3~6
NMF 20~35
Elastatinal 12~18
Its elastase inhibitor mainly include Gentrin Knotweed P.E, quassia alkaloid, one kind in anthocyanidin or with
On.
Further, described composition includes the component of following mass parts:
Antioxidant 4.2~5.8
NMF 24~31
Elastatinal 14~16
Its elastase inhibitor mainly include Gentrin Knotweed P.E, quassia alkaloid, one kind in anthocyanidin or with
On.
Further, described composition includes the component of following mass parts:
Antioxidant 4.8
NMF 29
Elastatinal 15
Its elastase inhibitor mainly include Gentrin Knotweed P.E, quassia alkaloid, one kind in anthocyanidin or with
On.
In addition, the antioxidant is included in Kiwi berry polysaccharide, iridin, apple polyphenol, vitamin C and its derivative
It is one or more of;
The NMF includes Sodium Hyaluronate, Ampelopsis grossedentata extrat, ceramide, glycerine, collagen, Fructus Luffae extract
In it is one or more of;
Composition of the present invention can be used for cosmetics, such as can be used for the product with effect of compacting as additive.
Compared with prior art, it is the device have the advantages that as follows:
(1) addition antioxidant can reduce skin oxidative damage, and delaying skin aging, Kiwi berry polysaccharide, iridin can
Free radical is removed, antioxidation is effectively played and can extend to form one layer of viscoplasticity film in skin surface, skin is more stepped up
Cause;
(2) adding NMF can not only moisturizing, moreover it is possible to forms water lock barrier in skin surface, Ampelopsis grossedentata extrat can suppress
Hyaluronidase activity, skin moisture is maintained, skin lack of moisture is prevented, effectively plays moisture-keeping function, it is tight so as to play indirectly
Cause the effect of skin;
(3) addition elastatinal can effectively compact skin, increase the elasticity of skin, and Gentrin Knotweed P.E effectively presses down
Elastoser processed, suppress wrinkle of skin generation, and then play a part of crease-resistant anti-aging, anthocyanidin can safeguard skin glue
Original synthesis, suppresses elastoser, is produced so as to reduce wrinkle, so as to recover the elasticity of skin, compact skin;
(4) acted synergistically between the skin composition components that compact of the invention, the effect for the skin that preferably compacts can be played, will
It is applied in cosmetics, can assign the good skin that compacts of cosmetics, oxidation resistant effect.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Compact the preparation of skin composition:
4.8 grams of Kiwi berry polysaccharide, 29 grams of Ampelopsis grossedentata extrats, 15 grams of Gentrin Knotweed P.Es, 51.2 grams of deionized waters are placed in mixed
In clutch, it is uniformly mixed, you can obtain the skin composition that compacts.
Embodiment 2
Compact the preparation of facial mask:
According to mass percent, 10% propane diols, 0.03% niacinamide, 8% glycerine, 15% butanediol, 3% β-Portugal are gathered
Sugar, 0.05% Sodium Hyaluronate, 0.05% panthenol, 0.5% allantoin, 0.6% hexylene glycol, 0.3%EDTA disodiums, 0.3% hydroxyl
Ethyl cellulose, 0.2% carbomer, 41.77% deionized water, which are added in agitated kettle, is heated with stirring to 85 DEG C, and stirring and dissolving is complete
Entirely, aqueous phase is made;By 0.3% glycerine polymethacrylates, 0.8% hydrolysis Jojoba esters, 0.5%PEG-40 hydrogenation castors
Sesame oil adds in agitated kettle and is heated with stirring to 85 DEG C, and oil phase is made;Under stirring, oil phase is added into aqueous phase, stirred;It is cooled to
45 DEG C, 0.1% triethanolamine is added, is stirred, added 8% and compact skin composition, 0.5% Phenoxyethanol, fully stir
Cooling discharging after mixing uniformly.
Embodiment 3
The preparation for emulsion of compacting:
It is according to mass percent, 3% stearine, 4% methyl sesquistearate, 2% sorb is smooth hard
Resin acid ester, 6% stearic acid, 8% stearyl alcohol, 1.5% OXYBENZONE Hybrid Heating are stirred to 85 DEG C, are produced after stirring and dissolving is complete
Oil phase;8% glycerine, 0.5% allantoin, 54.6% deionized water Hybrid Heating are stirred to 85 DEG C, stirring and dissolving is afterwards completely
Obtain aqueous phase;Oil phase is added in aqueous phase and stirred 30 minutes, temperature is maintained at 85 DEG C;Then 0.1% hydroxyethyl cellulose guarantor is added
Temperature stirring 30 minutes;It is cooled to 42 DEG C and adds 12% compact skin composition, 0.3% Phenoxyethanol and stirs, cooling discharging.
Embodiment 4
Compact frost preparation:
According to mass percent, by 10% caprylic/capric triglyceride, 1% cetostearyl alcohol, 2% 2 cetanol phosphoric acid
Ester, 2.5% white oil and 1% cyclic silicone oils heating stirring produce oil phase to 85 DEG C, and 0.5% is added into 64.6% deionized water
Xanthans and 3% glycerine, and be heated with stirring to 85 DEG C and produce aqueous phase, gained oil phase is continued to stir under vacuum, then
Aqueous phase is added into oil phase, and continues to stir and emulsifies, after emulsification, continues insulated and stirred 15min, hydrogen is added after being cooled to 40 DEG C
Sodium oxide molybdena adjusts pH to neutrality, adds 0.2% Phenoxyethanol, 15% compacts skin composition and 0.2% essence, fully
Stir.
Embodiment 5
Anti-oxidation efficacy is tested
At room temperature, in 4ml test tubes, phosphate buffer (pH 7.4) 0.5ml is sequentially added, 5 μ L 5,5- dimethyl-
1- pyrrolin-N oxides (DMP0), 250 μ L 0.1M H202, sample made from 1.5ml 0.1mM embodiments 1-4, while with
It is a it is commercially available declare that with antioxidation cosmetic product or skin care item be control group, 250 μ L 3mM FeS04 solution, in 6 minutes left sides
ESR detections are carried out in right injection quartz capillary.As a result such as table 1 below:
Table 1
Sequence number | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 | Control group |
Clearance rate | 90% | 91% | 93% | 93% | 75% |
It was found from the data of upper table 1,1-4 of the embodiment of the present invention is to the clearance rate of free radical apparently higher than control group, it is seen that this
The invention skin composition that compacts has very strong antioxidation activity, can remove free radical in time, effectively maintain the vigor of skin with
Elasticity.
Embodiment 6
Moisture-keeping efficacy is tested
Experiment material:Some pieces of the clean glass plates of 7.5 × 7.5cm, 3M adhesive plasters, 50~500 μ l liquid-transfering guns, assay balance,
Potassium acetate [KC2H3O2] saturated solution relative humidity about 60%, a ten thousandth balance, sample made from embodiment 1-4 and a
Commercially available moisture-keeping cosmetics are control group.
Experimental method and testing procedure:
(1) 6 pieces of glass plate weight (M for posting 3M adhesive plasters are weighed0), record respectively, 3 pieces are blank control, and 3 pieces are sample
Product are tested.
(2) take 200 μ l sample drops to be added on the glass plate for posting 3M adhesive plasters with liquid-transfering gun, the weight is weighed with assay balance
M1(being accurate to 0.0001g), sample is smoothened, and glass plate is put into the drier of the constant humidity of requirement, is repeated 3 times.By its
3 pieces of blank control glass plates of remaininging are put into the drier of constant humidity together.
(3) after 4h, 8h is placed, glass plate is taken out, weighs the glass plate weight (M2), test its moisturizing rate and relatively wet
Degree rate, it is immediately placed into after weighing in the drier of constant humidity.
(4) points for attention of this experiment:Smear as far as possible uniform during sample, it is impossible to have carry-over on applicator.Will
Sample, which takes out, to be weighed and is put into, and a drier control is within 15min, average 1 piece of glass plate 1min.Control time
It is due to that its moisture loss is very fast exposed to external environment for sample, test result can be had a strong impact on.Glass plate falls immediately after taking out
Put on preprepared blank glass plate, be also upside down in the container in balance during weighing.
(5) moisturizing rate calculation formula:
Moisturizing rate=(M2–M0)/(M1–M0) × 100%
In formula:
M0:Hollow plate quality/g
M1:Glass sheet quality/g after sample-adding
M2:Quality/g after some hours is placed in drier
Test its relative humidity be 60% when 4h and 8h in moisturizing rate.Result of the test is shown in Table 2:
Table 2
It was found from the data of upper table 2, the moisturizing rate of product made from embodiment 1-4 shows the present invention apparently higher than control group
The skin composition that compacts has excellent replenishing water and preserving moisture effect.
Embodiment 7
Anti-ageing efficacy test of compacting
Product prepared by embodiment 2-4 carries out clinical effect test, and its effect is assessed.Volunteer is 60
The female middle-aged of 40~50 years old or so, is divided into 3 groups, every group of 20 people;Position on probation is face's (test of half face);Method of testing:It is clean
Behind face, half of face is smeared, and twice a day, is smeared one month, observation and test position are right face.Test result is as shown in table 3:
Table 3
The result of table 3 is shown, either skin density, the skin elasticity still improvement to wrinkle, is made by embodiment 1-4
The product nursing of one month, be obtained for obvious improvement substantially, anti-ageing tightening effect is notable.
Above example only illustrates embodiment of the present invention, does not have any formal limitation to the present invention;Appoint
What is engaged in professional and technical personnel, all has the ability to make some changes or modification using the technology contents disclosed, turns into equivalent
The equivalent embodiment of change, according to the technology of the present invention essence, simple modification, equivalent change and modification is carried out to the present invention, belonged to
In the range of technical solution of the present invention.
Claims (5)
- The skin composition 1. one kind is compacted, it is characterised in that component includes with content:Antioxidant 3~6NMF 20~35Elastatinal 12~18It is mass parts above;Its elastase inhibitor mainly includes one or more of in Gentrin Knotweed P.E, quassia alkaloid, anthocyanidin.
- 2. composition as claimed in claim 1, it is characterised in that component includes with content:Antioxidant 4.2~5.8NMF 24~31Elastatinal 14~16It is mass parts above;Its elastase inhibitor mainly includes one or more of in Gentrin Knotweed P.E, quassia alkaloid, anthocyanidin.
- 3. composition as claimed in claim 2, it is characterised in that component includes with content:Antioxidant 4.8NMF 29Elastatinal 15It is mass parts above;Its elastase inhibitor mainly includes one or more of in Gentrin Knotweed P.E, quassia alkaloid, anthocyanidin.
- 4. the composition as described in claim any one of 1-3, it is characterised in that:The antioxidant include Kiwi berry polysaccharide, iridin, apple polyphenol, vitamin C and its derivative in one kind or with On;The NMF is included in Sodium Hyaluronate, Ampelopsis grossedentata extrat, ceramide, glycerine, collagen, Fructus Luffae extract It is one or more of.
- 5. the composition as described in Claims 1 to 4, it is characterised in that be used to prepare cosmetics as additive.
Priority Applications (1)
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CN201711242106.2A CN107822980A (en) | 2017-11-30 | 2017-11-30 | One kind is compacted skin composition |
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CN201711242106.2A CN107822980A (en) | 2017-11-30 | 2017-11-30 | One kind is compacted skin composition |
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CN107822980A true CN107822980A (en) | 2018-03-23 |
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CN201711242106.2A Withdrawn CN107822980A (en) | 2017-11-30 | 2017-11-30 | One kind is compacted skin composition |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104083318A (en) * | 2014-07-09 | 2014-10-08 | 广州市攸澜化妆品有限公司 | Skin-whitening cosmetic and preparation method thereof |
CN105748336A (en) * | 2014-12-20 | 2016-07-13 | 天津裕鼎广汇科技发展有限责任公司 | Plant type cosmetic |
-
2017
- 2017-11-30 CN CN201711242106.2A patent/CN107822980A/en not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104083318A (en) * | 2014-07-09 | 2014-10-08 | 广州市攸澜化妆品有限公司 | Skin-whitening cosmetic and preparation method thereof |
CN105748336A (en) * | 2014-12-20 | 2016-07-13 | 天津裕鼎广汇科技发展有限责任公司 | Plant type cosmetic |
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Application publication date: 20180323 |