CN107815414B - Carbon dioxide incubator transfer system - Google Patents

Carbon dioxide incubator transfer system Download PDF

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Publication number
CN107815414B
CN107815414B CN201710862136.7A CN201710862136A CN107815414B CN 107815414 B CN107815414 B CN 107815414B CN 201710862136 A CN201710862136 A CN 201710862136A CN 107815414 B CN107815414 B CN 107815414B
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carbon dioxide
trolley
box body
dioxide incubator
upper layer
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CN107815414A (en
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叶大林
夏信群
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Zhejiang Tailin Bioengineering Co ltd
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Zhejiang Tailin Bioengineering Co ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/52Mobile; Means for transporting the apparatus
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B62LAND VEHICLES FOR TRAVELLING OTHERWISE THAN ON RAILS
    • B62BHAND-PROPELLED VEHICLES, e.g. HAND CARTS OR PERAMBULATORS; SLEDGES
    • B62B3/00Hand carts having more than one axis carrying transport wheels; Steering devices therefor; Equipment therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Combustion & Propulsion (AREA)
  • Transportation (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Accommodation For Nursing Or Treatment Tables (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The invention relates to a carbon dioxide incubator transfer system, which comprises: the upper layer trolley is used for placing a carbon dioxide incubator during conveying and comprises a box body, and rollers are arranged at the bottom of the box body; the carbon dioxide storage tank is arranged on the box body of the upper trolley and supplies gas to the carbon dioxide incubator on the upper trolley during conveying so as to maintain the required internal gas environment of the carbon dioxide incubator; the UPS is arranged on the box body of the upper trolley and supplies power to the carbon dioxide incubator on the upper trolley during conveying so as to electrically heat the carbon dioxide incubator to maintain the culture temperature; and the upper part of the trolley is provided with an upper-layer slide rail for guiding the rollers at the bottom of the box body of the upper-layer trolley to slide into the placing position of the upper-layer trolley. The invention adopts the scheme of the movable transfer trolley which supplies gas and supplies power during movement, when the upper-layer trolley moves to the centralized culture position, the power supply and the gas source are plugged, and the conventional culture is carried out, thereby effectively avoiding the situations of transfer, power failure and gas failure of the carbon dioxide incubator.

Description

Carbon dioxide incubator transfer system
Technical Field
The invention relates to the technical field of biology, in particular to a carbon dioxide incubator transfer system.
Background
The carbon dioxide incubator is a device for culturing cells/tissues in vitro by simulating and forming a growth environment similar to cells/tissues in organisms in an incubator body, wherein the incubator requires stable temperature (37 ℃), stable carbon dioxide level (5%), constant pH value (pH value: 7.2-7.4) and higher relative saturation humidity (95%), and is widely used for culturing cells, tissues and certain special microorganisms.
The most basic requirement of the carbon dioxide incubator is to provide the most accurate and stable control of temperature, carbon dioxide concentration and humidity so as to facilitate the development of research work on the carbon dioxide incubator;
in the practical use process of the carbon dioxide incubator, particularly for the culture process of immune cells and the like which needs a long period, the conditions of transferring, powering off and gas (carbon dioxide) interruption of the carbon dioxide incubator inevitably occur in the process.
Disclosure of Invention
The invention mainly aims to provide a carbon dioxide incubator transfer system which can avoid the situations of transfer, power failure and gas failure of a carbon dioxide incubator.
The technical problem of the invention is mainly solved by the following technical scheme: a carbon dioxide incubator transfer system, comprising:
the upper layer trolley is used for placing a carbon dioxide incubator during conveying and comprises a box body, and rollers are arranged at the bottom of the box body;
the carbon dioxide storage tank is arranged on the box body of the upper trolley and supplies gas to the carbon dioxide incubator on the upper trolley during conveying so as to maintain the required internal gas environment of the carbon dioxide incubator;
the UPS is arranged on the box body of the upper trolley and supplies power to the carbon dioxide incubator on the upper trolley during conveying so as to electrically heat the carbon dioxide incubator to maintain the culture temperature;
and the upper part of the trolley is provided with an upper-layer slide rail for guiding the rollers at the bottom of the box body of the upper-layer trolley to slide into the placing position of the upper-layer trolley.
Through the technical scheme, the invention adopts a movable transfer trolley scheme which supplies gas and power during movement, an upper layer structure and a lower layer structure are arranged (namely, a trolley forms a lower layer, an upper layer trolley serves as an upper layer), the upper layer is provided with a UPS (uninterrupted power supply), a gas storage tank and a power socket, and the lower layer is provided with an upper layer slide rail; when the trolley moves to the position required by work, the trolley on the upper layer slides into the placing position along the sliding rail on the upper layer. When the upper trolley moves to the centralized culture position, the power supply and the air source are plugged, the conventional culture is carried out, and the conditions of transfer, power failure and air (carbon dioxide) cutoff of the carbon dioxide incubator are effectively avoided.
Drawings
FIG. 1 is a schematic diagram of the present invention.
Fig. 2 is a schematic view of a guide block.
Wherein: 1. pushing a cart; 2. an upper layer slide rail; 3. an upper layer trolley; 4. a carbon dioxide gas storage tank; 5. a UPS power supply; 6. a carbon dioxide incubator; 7. a timer; 8. a buzzer; 9. a lower layer slide rail; 10. and a guide block.
Detailed Description
The technical scheme of the invention is further specifically described by the following embodiments and the accompanying drawings.
Example (b): the invention relates to a carbon dioxide incubator transfer system, as shown in the attached figure 1, which comprises: an upper layer trolley 3, a carbon dioxide gas storage tank 4, a UPS power supply 5 and a trolley 1.
The upper layer trolley 3 is used for placing a carbon dioxide incubator 6 during conveying and comprises a box body, and rollers are arranged at the bottom of the box body;
and a carbon dioxide gas storage tank 4 which is arranged on the box body of the upper layer trolley 3 and supplies gas to the carbon dioxide incubator 6 on the upper layer trolley 3 during transportation so that the carbon dioxide incubator 6 maintains a required internal gas environment.
And the UPS (uninterrupted Power supply) 5 is arranged on the box body of the upper layer trolley 3, supplies power to the carbon dioxide incubator 6 on the upper layer trolley 3 during conveying, and supplies electric heating for the carbon dioxide incubator 6 to maintain the culture temperature.
The trolley comprises a trolley 1, wherein the upper part of the trolley 1 is provided with a platform, an upper sliding rail 2 for guiding the roller at the bottom of a box body of an upper trolley 3 to slide into the placing position of the upper trolley 3 is arranged on the platform, and the upper sliding rail 2 is of a groove body structure matched with the roller and moves towards the front end and the rear end of the trolley; and (3) moving the upper trolley 3 and the carbon dioxide incubator 6 out of or into the platform by using the upper slide rail 2. The front part of the cart 1 is provided with a guide block 10 which is hung on the docking equipment; when the cart 1 is close to the docking device, the guide block 10 is matched with a corresponding structure (such as a hole, a groove and the like) on the docking device, so that the cart 1 enters an accurate position to ensure that the upper sliding rail 2 is aligned with the end part of the sliding rail on the docking device, and the upper cart 3 and the carbon dioxide incubator 6 can be quickly and accurately transferred between the cart 1 and the docking device.
In order to further improve the accuracy of the docking action, the following further optimization scheme can be adopted, as shown in fig. 2, two pairs of guide blocks 10 are respectively arranged at two ends of the front part of the cart 1; the guide block 10 is provided with an open slot, the bottom of the open slot is arc-shaped, and the slot is an outward-expanded flaring; wherein, the open slot of one guide block 10 is located at the front end of the guide block 10, and the open slot of the other guide block 10 is located at the inner side; two guide columns are arranged outside the butt joint side of the butt joint equipment, each guide column is provided with a cylindrical section, and the diameter of each cylindrical section is matched with the arc-shaped bottom of each open slot; when in butt joint, the trolley 1 is close to the butt joint equipment, the guide block with the open slot at the front end is clamped into the corresponding guide column, the arc-shaped bottom is abutted against the cylindrical section of the guide column, then the trolley is pushed to rotate by taking the guide column as the center until the open slot at the side part of the other guide block 10 is clamped into the cylindrical section of the other guide column, so that the positioning of the trolley 1 and the alignment of the upper sliding rail 2 are completed. By adopting the structure, the trolley 1 can more accurately enter the butt joint position and is aligned in two vertical directions, the accuracy of alignment of the upper sliding rail 2 on the trolley 1 and the end part of the sliding rail on the butt joint equipment is improved, the transfer of the upper trolley 3 and the carbon dioxide incubator 6 is quicker and more stable, and the situation that the culture state of a culture in the carbon dioxide incubator 6 is influenced due to the fact that the carbon dioxide incubator 6 vibrates in the transfer process because of insufficient alignment accuracy is avoided.
In actual use, due to different specifications of the docking equipment, the docking position of the cart 1 is different; therefore, the invention provides a better technical scheme: the platform at the upper part of the cart 1 is a movable platform, and the moving direction is approximately the same as the guiding direction of the upper-layer guide rail 2; the mechanism for driving the platform to move comprises a lower-layer slide rail 9 arranged at the bottom of the platform and a spiral driving mechanism. The platform can be fixed on the cart 1 in a sliding way through the lower-layer sliding rail 9; operating the screw driving mechanism to drive the platform to move; after the trolley 1 is aligned with the butt joint equipment, the position of the platform can be adjusted in real time through the spiral driving mechanism, so that the upper-layer trolley 3 and the carbon dioxide incubator 6 enter a better transfer position.
For the culture of cells, tissues and some special microorganisms, the external environment purification degree is improved, the pollution from the outside is reduced, and the success rate of the culture is favorably improved; the interior of the box body of the upper layer trolley 3 is not easy to degerming and needs to be degerming regularly; even if the sterilization is carried out regularly, the external pollution is not easy to completely eradicate. Therefore, the invention provides a better solution, and the box body of the upper layer trolley 3 is set to be a closed structure with an internal space isolated from an external space; after the sealed structure is adopted, the inside and the outside of the box body are completely isolated, regular sterilization is not needed, pollution sources are completely isolated, and labor intensity is reduced.
In order to further reduce the source of bacterial pollution, the carbon dioxide gas storage tank 4 is arranged inside the box body of the upper layer trolley 3, the gas pipe of the carbon dioxide gas storage tank passes through the side wall of the box body, and the penetrating part of the gas pipe is provided with a sealing ring to form sealing connection. The UPS power supply 5 is arranged in the box body of the upper layer trolley 3, a cable of the UPS power supply penetrates through the side wall of the box body, and a penetrating part is provided with a sealing ring to form sealing connection. A carbon dioxide gas storage tank 4 and a UPS power supply 5 are arranged in the closed box body of the upper layer trolley 3 and are completely isolated from the external space. The sealed box body has a built-in structure, for example, a structure having a cover, and after the carbon dioxide gas storage tank 4 and the UPS power supply 5 are installed in the box body, the cover is installed, and a joint portion between the cover and the box body is provided with a sealing connection.
Because the UPS 5 can generate certain heat when working, although the heat is smaller, in order to ensure the stability of long-term operation, the invention provides a better alternative scheme: the upper part of the box body of the upper layer trolley 3 is provided with a heat insulation structure to prevent heat from being directly transferred to the carbon dioxide incubator 6; the side part or the bottom part of the box body is provided with a heat conducting part made of heat conducting materials so as to transfer heat in the box body to the outside of the box body through heat transfer; the outer side of the UPS 5 is provided with a metal component for heat conduction, and the tail end of the metal component is connected with a heat conduction part on the box body of the upper layer trolley 3. The heat of the UPS 5 is transferred to the heat conducting part through the metal component, and the heat conducting part is transferred to the outer side of the box body, so that the temperature of the UPS 5 during working is reduced.
The invention improves the existing problems based on the basic requirements of users on the incubator, provides the technical scheme of the transfer trolley consisting of the upper trolley and the trolley, and arranges the UPS uninterrupted power supply and the carbon dioxide storage tank in the upper trolley, so that the carbon dioxide incubator can continuously supply power and gas in the transfer process. The upper layer trolley has a timing function, when the UPS is cut off and charging starts to time, timing time can be set, and when the timing time is up, the buzzer gives an alarm to prompt charging. In the actual use process, especially for the culture process of a longer period of immune cell culture, the situations of transferring, power failure and gas (carbon dioxide) cutoff of a carbon dioxide incubator are effectively avoided.
The above description is only for the specific embodiments of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art can easily conceive of the changes or substitutions within the technical scope of the present invention, and all the changes or substitutions should be covered within the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the appended claims.

Claims (6)

1. A carbon dioxide incubator transfer system, characterized by comprising:
the upper layer trolley (3) is used for placing a carbon dioxide incubator (6) during conveying and comprises a box body, and rollers are arranged at the bottom of the box body;
the carbon dioxide storage tank (4) is arranged on the box body of the upper layer trolley (3) and supplies gas to the carbon dioxide incubator (6) on the upper layer trolley (3) during conveying so as to maintain the carbon dioxide incubator (6) in a required internal gas environment;
the UPS power supply (5) is arranged on the box body of the upper layer trolley (3), supplies power to the carbon dioxide incubator (6) on the upper layer trolley (3) during conveying, and supplies electric heating to the carbon dioxide incubator (6) to maintain the culture temperature;
the upper part of the trolley (1) is provided with an upper-layer slide rail (2) for guiding the bottom roller of the upper-layer trolley (3) to slide into a placing position;
the front part of the cart (1) is provided with a guide block (10) which is hung with butt joint equipment; the guide blocks (10) are divided into two pairs and are respectively arranged at two ends of the front part of the trolley (1); the guide block (10) is provided with an open slot, the bottom of the open slot is arc-shaped, and the open slot is an outward-expanded flaring; wherein, the open slot of one guide block (10) is positioned at the front end part of the guide block (10), and the open slot of the other guide block (10) is positioned at the inner side part; two guide columns are arranged outside the butt joint side of the butt joint equipment, each guide column is provided with a cylindrical section, and the diameter of each cylindrical section is matched with the arc-shaped bottom of each open slot; when in butt joint, the trolley (1) is close to the butt joint equipment, a guide block with an open slot at the front end is clamped into the corresponding guide column, the arc-shaped bottom is abutted against the cylindrical section of the guide column, then the trolley (1) is pushed to rotate by taking the guide column as the center until the open slot at the side part of the other guide block (10) is clamped into the cylindrical section of the other guide column, so that the positioning of the trolley (1) and the alignment of the upper sliding rail (2) are completed.
2. A carbon dioxide incubator transport system according to claim 1, characterised in that: the box body of the upper layer trolley (3) is of a closed structure with an internal space isolated from an external space.
3. A carbon dioxide incubator transport system according to claim 2, characterised in that: the UPS power supply (5) is arranged in the box body of the upper layer trolley (3), a cable of the UPS power supply penetrates through the side wall of the box body, and a penetrating part of the UPS power supply is provided with a sealing ring to form sealing connection.
4. A carbon dioxide incubator transport system according to claim 3, characterised in that: the side part or the bottom part of the box body of the upper layer trolley (3) is provided with a heat conducting part made of heat conducting materials so as to transfer heat in the box body to the outside of the box body through heat transfer; the UPS power supply (5) is provided with a metal component for heat conduction at the outer side, and the tail end of the metal component is connected with a heat conduction part on the box body of the upper layer trolley (3).
5. A carbon dioxide incubator transport system according to claim 2, characterised in that: the carbon dioxide gas storage tank (4) is arranged in the upper layer trolley (3) box body, a gas pipe of the carbon dioxide gas storage tank penetrates through the side wall of the box body, and a sealing ring is arranged at the penetrating part of the gas pipe to form sealing connection.
6. A carbon dioxide incubator transport system according to claim 1 or 2 or 3 or 4 or 5, characterised in that: the platform at the upper part of the cart (1) is a movable platform, and the moving direction is approximately the same as the guiding direction of the upper sliding rail (2); the mechanism for driving the platform to move comprises a lower-layer slide rail (9) arranged at the bottom of the platform and a spiral driving mechanism.
CN201710862136.7A 2017-09-21 2017-09-21 Carbon dioxide incubator transfer system Active CN107815414B (en)

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Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
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CN107815414B true CN107815414B (en) 2020-11-24

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2884096Y (en) * 2006-03-01 2007-03-28 何宗荣 Casing door structure having simple hand-cart positioning and locking position device
CN201143275Y (en) * 2008-01-04 2008-11-05 陈再宏 Incubator for transporting baby
CN204874550U (en) * 2015-07-21 2015-12-16 湖北华赛生物医药技术有限公司 Carbon dioxide incubator
CN105252242A (en) * 2015-09-06 2016-01-20 吕亮霞 Movement and pose adjusting platform for large member
RU2609657C1 (en) * 2015-10-22 2017-02-02 федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Method for extracting mesenchymal stem cells from orbital adipose tissue
CN206012409U (en) * 2016-08-25 2017-03-15 广东嘉腾机器人自动化有限公司 A kind of AGV carriers with loading and unloading docking facilities

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2884096Y (en) * 2006-03-01 2007-03-28 何宗荣 Casing door structure having simple hand-cart positioning and locking position device
CN201143275Y (en) * 2008-01-04 2008-11-05 陈再宏 Incubator for transporting baby
CN204874550U (en) * 2015-07-21 2015-12-16 湖北华赛生物医药技术有限公司 Carbon dioxide incubator
CN105252242A (en) * 2015-09-06 2016-01-20 吕亮霞 Movement and pose adjusting platform for large member
RU2609657C1 (en) * 2015-10-22 2017-02-02 федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Method for extracting mesenchymal stem cells from orbital adipose tissue
CN206012409U (en) * 2016-08-25 2017-03-15 广东嘉腾机器人自动化有限公司 A kind of AGV carriers with loading and unloading docking facilities

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