CN107811904A - Anti-inflammatory nti-freckle toilet cream and preparation method thereof - Google Patents

Anti-inflammatory nti-freckle toilet cream and preparation method thereof Download PDF

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CN107811904A
CN107811904A CN201711023963.3A CN201711023963A CN107811904A CN 107811904 A CN107811904 A CN 107811904A CN 201711023963 A CN201711023963 A CN 201711023963A CN 107811904 A CN107811904 A CN 107811904A
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parts
component
freckle
cannabidiol
inflammatory
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CN107811904B (en
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项伟
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Yunnan Han Musen Biotechnology LLC
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Yunnan Han Musen Biotechnology LLC
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95

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Abstract

The invention discloses a kind of anti-inflammatory nti-freckle toilet cream and preparation method thereof, the crease-resistant toilet cream of nti-freckle containing fiery sesame slices extract includes the component of following parts by weight:5~8 parts of white oil, 7~12 parts of albolene, 7~13 parts of glycerin monostearate, 1~9 part of hemp-seed oil, 15~25 parts of lanolin, special fiery 3~8 parts of the sesame slices extract for being enriched with bisabolol and cannabidiol, 0~0.2 part of vitamin E, 0.2~0.3 part of triethanolamine, 0.2~0.3 part of essence, 0.03~0.05 part of preservative, 30~60 parts of deionized water.Anti-inflammatory nti-freckle toilet cream in the present invention adds the special fiery sesame slices extract of enrichment bisabolol and cannabidiol, this extract has obvious anti-inflammatory and Eradicates spot and other effects, the bisabolol collaboration for wherein retaining enrichment strengthens the anti-inflammatory and Eradicates spot effectiveness of cannabidiol, and fiery sesame slices extract can be maintained to play stronger anti-inflammatory and Eradicates spots and other effects in longer time.

Description

Anti-inflammatory nti-freckle toilet cream and preparation method thereof
Technical field
The present invention relates to cosmetic technical field, and in particular to a kind of anti-inflammatory nti-freckle toilet cream and preparation method thereof.
Background technology
Quickly risen abruptly in US and European, a new series cosmetics, the extraction species cosmetics of marihuana within nearly 2 years Rise, start fashionable functional cosmetics consumption market.Cosmetics made of the extract of this industrial hemp leaf are considered to have Treat dermatophyte or bacterium infection, analgesic, anti-inflammatory, Eradicates spots, anti-ageing and crease-resistant and other effects.2016, MGC Pharma companies The cosmetics of extraction species of industrial hemp leaf ratify through the European cosmetics committee, listed in all Europe.
We are in correlation it was found that, main active in application of the in general fire sesame slices extract in cosmetics It is conventionally known cannabidiol (Cannabidiol), but many people do not know, or carelessness, to miss another big Anti-inflammatory and anti-irritant active component in sesame slices, bisabolol (Alpha-bsabolol);The natural opopanax applied in the past Alcohol mainly comes from yellow chamomile.It can be used for protecting and nursing allergic skin, while have good sterilization and anti-inflammatory Effect.In addition, bisabolol has the characteristics of increasing other active component penetrability, can add in cannabidiol isoreactivity composition Enter amount it is relatively small when, help their preferably absorbing transmission from skin, improve absorptivity, play medical active.Bisabolol is also There is good skin-friendliness.Bisabolol self stability is fine, can help to extend the cosmetics shelf-life.
For above reason, we use modern plants chemical technology, enrichment bisabolol are extracted from industrial hemp With the special fiery sesame slices extract of cannabidiol, it is below the mark that toxic component THC is fallen below into international management and control, and Optionally retain in this enrichment bisabolol and the special fiery sesame slices extract of cannabidiol and be enriched bisabolol and big Numb two main actives of diphenol.According to different requirements, this enrichment bisabolol and the special fiery sesame slices extraction of cannabidiol Bisabolol content in thing is 0.1% to 15%, and cannabidiol content is 10% to 80%.
The content of the invention
It is an object of the invention to provide a kind of anti-inflammatory nti-freckle toilet cream and preparation method thereof, solve for allergic skin For, many nti-freckle products do not have anti-inflammatory and antianaphylaxis energy, and long-term use easily causes more serious skin problem Problem.
To solve above-mentioned technical problem, the present invention uses following technical scheme:
A kind of anti-inflammatory nti-freckle toilet cream, include the component of following parts by weight:5~8 parts of white oil, 7~12 parts of albolene, list 7~13 parts of tristerin, 1~9 part of hemp-seed oil, 15~25 parts of lanolin, enrichment bisabolol and cannabidiol it is special With fiery 3~8 parts of sesame slices extract, 0~0.2 part of vitamin E, 0.2~0.3 part of triethanolamine, 0.2~0.3 part of essence, anti-corrosion 0.03~0.05 part of agent, 30~60 parts of deionized water.
Preferably, a kind of anti-inflammatory nti-freckle toilet cream, include the component of following parts by weight:6~8 parts of white oil, albolene 7 ~10 parts, 7~10 parts of glycerin monostearate, 1~4 part of hemp-seed oil, 15~20 parts of lanolin, enrichment bisabolol and hemp Special fiery 5~8 parts of sesame slices extract, 0.1 part of vitamin E, 0.3 part of triethanolamine, 0.3 part of essence, the preservative 0.05 of diphenol Part, 40~60 parts of deionized water.
Preferably, a kind of anti-inflammatory nti-freckle toilet cream, include the component of following parts by weight:7~8 parts of white oil, albolene 8 ~9 parts, 9~10 parts of glycerin monostearate, 3~4 parts of hemp-seed oil, 20~25 parts of lanolin, enrichment bisabolol and hemp Special fiery 5~6 parts of sesame slices extract, 0.1 part of vitamin E, 0.3 part of triethanolamine, 0.3 part of essence, the preservative 0.05 of diphenol Part, 40~47 parts of deionized water.
Preferably, the extracting method of the special fiery sesame slices extract of the enrichment bisabolol and cannabidiol is:
A1:From industrial hemp leaf, it is dried in 105 DEG C of temperature, and applies " overcritical titanium dioxide after being pulverized Carbon extraction apparatus " extracts, and after filtering and crude separation, concentrates as extractum A;
A2:Extractum A is utilized into thin layer chromatography technology, by normal-phase chromatography filler and reversed phase chromatography filler isolate effectively into Dividend bisabol and cannabidiol;
A3:It is 0.1%~15% that bisabolol is enriched into content, and cannabidiol content is 10%~80%, obtains richness Collect the special fiery sesame slices extract of bisabolol and cannabidiol.
A kind of preparation method of anti-inflammatory nti-freckle toilet cream, comprises the following steps:
S0:By white oil, albolene, glycerin monostearate, hemp-seed oil, lanolin, enrichment bisabolol and hemp The special fiery sesame slices extract and vitamin E of diphenol are as component A, using triethanolamine and deionized water as component B, by essence With preservative as component C;
S1:It is constant that component A is heated to 60~80 DEG C of keeping temperatures;
S2:It is constant that component B is heated to 60~80 DEG C of keeping temperatures;
S3:In the case of lasting stirring, component A is slowly added in component B, allows two groups of components to be sufficiently mixed emulsification;
S4:In the case of lasting stirring, when temperature is down to 35~55 DEG C, component C is added, continues stirring and allows all groups Divide and be sufficiently mixed emulsification;
S5:After being cooled to room temperature, bottling.
Preferably, the component A is by weight, including 5~8 parts of white oil, 7~12 parts of albolene, monostearate 7~13 parts of glyceride, 1~9 part of hemp-seed oil, 15~25 parts of lanolin, the special fire fiber crops for being enriched with bisabolol and cannabidiol 3~8 parts of leaf extract, 0~0.2 part of vitamin E.
Preferably, the component B is by weight, including 0.2~0.3 part of triethanolamine and deionized water 30~60 Part.
Preferably, the component C is by weight, including 0.03~0.05 part of 0.2~0.3 part of essence and preservative.
Compared with prior art, the beneficial effects of the invention are as follows:
Anti-inflammatory nti-freckle toilet cream in the present invention adds the special fiery sesame slices extraction of enrichment bisabolol and cannabidiol Thing, this extract have obvious anti-inflammatory and Eradicates spot and other effects, wherein the bisabolol collaboration for retaining enrichment strengthens hemp The anti-inflammatory and Eradicates spot effectiveness of diphenol, can maintain fiery sesame slices extract to play the work(such as stronger anti-inflammatory and Eradicates spots in longer time Effect;And the vitamin E collaboration added strengthens anti-ageing and crease-resistant effectiveness.
Raw material in the present invention is simple, selected from natural plant extracts, is free from side effects;The manufacturing process of the present invention simultaneously Simply, it is readily produced processing.
Embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
Embodiment 1:
A kind of anti-inflammatory nti-freckle toilet cream, include following weight g component:White oil 5g, albolene 7g, glycerol monostearate Ester 7g, hemp-seed oil 1g, lanolin 15g, special fiery sesame slices extract 3g, the triethanolamine for being enriched with bisabolol and cannabidiol 0.2g, essence 0.2g, preservative 0.03g, deionized water 30g.
Embodiment 2:
A kind of anti-inflammatory nti-freckle toilet cream, include following weight g component:White oil 8g, albolene 12g, monostearate are sweet Grease 13g, hemp-seed oil 9g, lanolin 25g, the special fiery sesame slices extract 8g for being enriched with bisabolol and cannabidiol, dimension life Plain E0.2g, triethanolamine 0.3g, essence 0.3g, preservative 0.05g, deionized water 60g.
Embodiment 3:
A kind of anti-inflammatory nti-freckle toilet cream, include following weight g component:White oil 6g, albolene 10g, monostearate are sweet Grease 10g, hemp-seed oil 7g, lanolin 20g, the special fiery sesame slices extract 5g for being enriched with bisabolol and cannabidiol, dimension life Plain E 0.1g, triethanolamine 0.2g, essence 0.2g, preservative 0.04g, deionized water 50g.
Embodiment 4:
A kind of anti-inflammatory nti-freckle toilet cream, include following weight g component:White oil 6g, albolene 7g, glycerol monostearate Ester 7g, hemp-seed oil 1g, lanolin 15g, special fiery sesame slices extract 5g, the vitamin for being enriched with bisabolol and cannabidiol E0.1g, triethanolamine 0.3g, essence 0.3g, preservative 0.05g, deionized water 40g.
Embodiment 5:
A kind of anti-inflammatory nti-freckle toilet cream, include following weight g component:White oil 8g, albolene 10g, monostearate are sweet Grease 10g, hemp-seed oil 4g, lanolin 20g, the special fiery sesame slices extract 8g for being enriched with bisabolol and cannabidiol, dimension life Plain E0.1g, triethanolamine 0.3g, essence 0.3g, preservative 0.05g, deionized water 60g.
Embodiment 6:
A kind of anti-inflammatory nti-freckle toilet cream, include following weight g component:White oil 7g, albolene 9g, glycerol monostearate Ester 9g, hemp-seed oil 3g, lanolin 18g, special fiery sesame slices extract 6g, the vitamin for being enriched with bisabolol and cannabidiol E0.1g, triethanolamine 0.3g, essence 0.3g, preservative 0.05g, deionized water 50g.
Embodiment 7:
A kind of anti-inflammatory nti-freckle toilet cream, include following weight g component:White oil 7g, albolene 8g, glycerol monostearate Ester 9g, hemp-seed oil 3g, lanolin 20g, special fiery sesame slices extract 5g, the vitamin for being enriched with bisabolol and cannabidiol E0.1g, triethanolamine 0.3g, essence 0.3g, preservative 0.05g, deionized water 40g.
Embodiment 8:
A kind of anti-inflammatory nti-freckle toilet cream, include following weight g component:White oil 8g, albolene 9g, glycerol monostearate Ester 10g, hemp-seed oil 4g, lanolin 25g, special fiery sesame slices extract 6g, the vitamin for being enriched with bisabolol and cannabidiol E0.1g, triethanolamine 0.3g, essence 0.3g, preservative 0.05g, deionized water 47g.
Carried for the enrichment bisabolol in embodiment 1~8 any one embodiment and the special fiery sesame slices of cannabidiol Taking the extracting method of thing is:
A1:From No. 7 leaves of yunnan polytechnic hemp, it is dried in 105 DEG C of temperature, and after being pulverized using " super to face Boundary's carbon dioxide draw instrument " extracts, and after filtering and crude separation, concentrates as extractum A;
A2:Extractum A is utilized into thin layer chromatography technology, by normal-phase chromatography filler and reversed phase chromatography filler isolate effectively into Dividend bisabol and cannabidiol;Remove the toxic components such as THC and unwanted contributions;
A3:It is 0.1%~15% that bisabolol is enriched into content, and cannabidiol content is 10%~80%, obtains richness Collect the special fiery sesame slices extract of bisabolol and cannabidiol.
The main component of the special fiery sesame slices extract of enrichment bisabolol and cannabidiol in embodiment 1~8 is red Bisabol and cannabidiol;Main component is cannabidiol in general fire sesame slices extract, can be used for protecting and nursed Quick property skin, while there are good sterilization and anti-inflammatory effects;Bisabolol has the spy for increasing other active component penetrability Point, their preferably absorbing transmission from skin can be helped when cannabidiol isoreactivity composition addition is relatively small, improve and inhale Yield, play medical active.
The preparation method of anti-inflammatory nti-freckle toilet cream in any one embodiment of embodiment 1~8, comprises the following steps:
S0:By white oil, albolene, glycerin monostearate, hemp-seed oil, lanolin, enrichment bisabolol and hemp The special fiery sesame slices extract and vitamin E of diphenol are as component A, using triethanolamine and deionized water as component B, by essence With preservative as component C;
S1:It is constant that component A is heated to 60~80 DEG C of keeping temperatures;
S2:It is constant that component B is heated to 60~80 DEG C of keeping temperatures;
S3:In the case of lasting stirring, component A is slowly added in component B, allows two groups of components to be sufficiently mixed emulsification;
S4:In the case of lasting stirring, when temperature is down to 35~55 DEG C, component C is added, continues stirring and allows all groups Divide and be sufficiently mixed emulsification;
S5:After being cooled to room temperature, bottling.
Anti-inflammatory nti-freckle toilet cream in the present invention adds the special fiery sesame slices extraction of enrichment bisabolol and cannabidiol Thing, this extract have obvious anti-inflammatory and Eradicates spot and other effects, wherein the bisabolol collaboration for retaining enrichment strengthens hemp The anti-inflammatory and Eradicates spot effectiveness of diphenol, can maintain fiery sesame slices extract to play the work(such as stronger anti-inflammatory and Eradicates spots in longer time Effect;And the vitamin E collaboration added strengthens anti-ageing and crease-resistant effectiveness.
Raw material is divided into three groups by the anti-inflammatory nti-freckle toilet cream in the present invention in the preparation, and wherein A groups oil is molten, and B groups are water-soluble, C To Be Protected from Heat for group, therefore is easy to the making of product after property identical raw material is mixed, and performs to the effect of final products It is maximum.60~80 DEG C are the temperature for being easier emulsification, are more suitable for each component and carry out mixing and emulsifying;Because essence can not be born Higher temperature, therefore temperature is set as 35~55 DEG C, prevent essence to be destroyed.
Experimental example:Selecting 90 personnel is divided into 9 groups of carry out product experiments at random, and the 1st~8 group uses embodiment 1~8 respectively Obtained product, the 9th group of product using common nti-freckle on the market, its experimental data are as shown in table 1.
Table 1
From table 1 and embodiment contrast is as can be seen that the positive effect of the nti-freckle in various embodiments of the present invention is better than commonly Nti-freckle product;Vitamin E is not added in additional embodiment 1, embodiment 2~8 adds vitamin E, therefore adds dimension Raw plain E freckle effect is substantially better than effect when not adding vitamin E.
In addition, having 23 entitled sensitive in above-mentioned 90 experimenters in the 1st group~the 8th group, there are 3 in the 9th group For sensitive;Find that there are 23 entitled sensitive in the 1st group~the 8th group using embodiment 1~8 by experiment Do not occur allergic sex chromosome mosaicism during product, but also there is certain anti-inflammatory efficacy, can quickly eliminate scytitis;And the There is allergy sex chromosome mosaicism in 3 sensitive experimenters in 9 groups.Thus, it could be seen that the anti-inflammatory nti-freckle product in the present invention Safely and effectively, various types of skins can be effectively antagonized, there is obvious anti-inflammatory and spot-removal function.
Although reference be made herein to invention has been described for multiple explanatory embodiments of the invention, however, it is to be understood that Those skilled in the art can be designed that a lot of other modifications and embodiment, and these modifications and embodiment will fall in this Shen Please be within disclosed spirit and spirit.More specifically, can be to master in the range of disclosure and claim The building block and/or layout for inscribing composite configuration carry out a variety of variations and modifications.Except what is carried out to building block and/or layout Outside modification and improvement, to those skilled in the art, other purposes also will be apparent.

Claims (8)

  1. A kind of 1. anti-inflammatory nti-freckle toilet cream, it is characterised in that:Include the component of following parts by weight:5~8 parts of white oil, albolene 7 ~12 parts, 7~13 parts of glycerin monostearate, 1~9 part of hemp-seed oil, 15~25 parts of lanolin, enrichment bisabolol and hemp Special fiery 3~8 parts of sesame slices extract, 0~0.2 part of vitamin E, 0.2~0.3 part of triethanolamine, the essence 0.2~0.3 of diphenol Part, 0.03~0.05 part of preservative, 30~60 parts of deionized water.
  2. 2. anti-inflammatory nti-freckle toilet cream according to claim 1, it is characterised in that:Include the component of following parts by weight:White oil 6 ~8 parts, it is 7~10 parts of albolene, 7~10 parts of glycerin monostearate, 1~4 part of hemp-seed oil, 15~20 parts of lanolin, rich Collect special fiery 5~8 parts of sesame slices extract, 0.1 part of vitamin E, 0.3 part of triethanolamine, the essence of bisabolol and cannabidiol 0.3 part, 0.05 part of preservative, 40~60 parts of deionized water.
  3. 3. anti-inflammatory nti-freckle toilet cream according to claim 2, it is characterised in that:Include the component of following parts by weight:White oil 7 ~8 parts, 8~9 parts of albolene, 9~10 parts of glycerin monostearate, 3~4 parts of hemp-seed oil, 20~25 parts of lanolin, enrichment Special fiery 5~6 parts of sesame slices extract, 0.1 part of vitamin E, 0.3 part of triethanolamine, the essence 0.3 of bisabolol and cannabidiol Part, 0.05 part of preservative, 40~47 parts of deionized water.
  4. 4. the anti-inflammatory nti-freckle toilet cream according to claims 1 to 3 any one, it is characterised in that:The enrichment opopanax The extracting method of the special fiery sesame slices extract of alcohol and cannabidiol is:
    A1:From industrial hemp leaf, it is dried in 105 DEG C of temperature, and after being pulverized using " supercritical carbon dioxide carries Take instrument " extraction, after filtering and crude separation, concentrate as extractum A;
    A2:Extractum A is utilized into thin layer chromatography technology, it is red to isolate active ingredient by normal-phase chromatography filler and reversed phase chromatography filler Bisabol and cannabidiol;
    A3:Bisabolol is enriched to content as 0.1%~15%, cannabidiol content is 10%~80%, obtains being enriched with red The special fiery sesame slices extract of bisabol and cannabidiol.
  5. A kind of 5. preparation method of anti-inflammatory nti-freckle toilet cream, it is characterised in that:Comprise the following steps:
    S0:By white oil, albolene, glycerin monostearate, hemp-seed oil, lanolin, enrichment bisabolol and cannabidiol Special fiery sesame slices extract and vitamin E as component A, using triethanolamine and deionized water as component B, by essence and anti- Rotten agent is as component C;
    S1:It is constant that component A is heated to 60~80 DEG C of keeping temperatures;
    S2:It is constant that component B is heated to 60~80 DEG C of keeping temperatures;
    S3:In the case of lasting stirring, component A is slowly added in component B, allows two groups of components to be sufficiently mixed emulsification;
    S4:In the case of lasting stirring, when temperature is down to 35~55 DEG C, component C is added, continues stirring and allows all components to fill Divide mixing and emulsifying;
    S5:After being cooled to room temperature, bottling.
  6. 6. the preparation method of anti-inflammatory nti-freckle toilet cream according to claim 5, it is characterised in that:The component A is by weight Part meter, including 5~8 parts of white oil, 7~12 parts of albolene, 7~13 parts of glycerin monostearate, 1~9 part of hemp-seed oil, wool Special fiery 3~8 parts of sesame slices extract, 0~0.2 part of the vitamin E of 15~25 parts of fat, enrichment bisabolol and cannabidiol.
  7. 7. the preparation method of anti-inflammatory nti-freckle toilet cream according to claim 5, it is characterised in that:The component B is by weight Part meter, including 30~60 parts of 0.2~0.3 part of triethanolamine and deionized water.
  8. 8. the preparation method of anti-inflammatory nti-freckle toilet cream according to claim 5, it is characterised in that:The component C is by weight Part meter, including 0.03~0.05 part of 0.2~0.3 part of essence and preservative.
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