CN107773730A - A kind of medicine for treating insomnia and preparation method thereof - Google Patents
A kind of medicine for treating insomnia and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention provides a kind of medicine for treating insomnia and preparation method thereof.The medicine is composed of the following components in parts by weight：20 40 parts of spina date seed；20 30 parts of the Radix Astragali；15 20 parts of the fruit of Chinese magnoliavine；10 15 parts of polygala；10 15 parts of root tuber of aromatic turmeric；58 parts of the seed of Oriental arborvitae；15 20 parts of pseudo-ginseng；58 parts of cape jasmine；10 15 parts of dried pinellia；10 20 parts of radix glycyrrhizae；1 20 parts of auxiliary material.It is demonstrated experimentally that medicine of the present invention can reach the effect for the treatment of and relieving insomnia.
Description
Technical field
The present invention relates to medicine and preparing technical field, more particularly to a kind of medicine for treating insomnia and preparation method thereof.
Background technology
Insomnia refers to the sleep state that can not fall asleep or can not keep, and causes to have not enough sleep.Also known as fall asleep and maintain sleep to hinder
Hinder, cause difficulty falling asleep, Depth of sleep or frequency be too short, early awakening and the length of one's sleep insufficient or of poor quality etc. for a variety of causes, be
A kind of common disease.The sense of fatigue of people can be caused, uneasiness, general malaise, listless, delay of response, headache, memory are not concentrated
Serious a little to cause schizophrenia in terms of its maximum effect is spirit etc. symptom, common clinical type has：Primary
Sleep-disorder, Secondary cases sleep-disorder, pseudoinsomnia.
The insomnia of Western medicine opioid therapy is the control of disperse accumulations or forces sleep, it is impossible to improve sleep quality, and chemical town
The quiet dose of toxic side effect to nerve, internal organs is that people early have common recognition.The traditional Chinese medical science clinically also has some as such as Buxin Pills, magnetic Zhu
The Chinese patent drugs such as ball, zhusha anshen pills, but they do not obtain gratifying effect in curative effect.Absorption is to influence Chinese medicine
One key factor of curative effect, therefore it is badly in need of the medicine for searching out a kind of good effect, the treatment of good absorbing is had a sleepless night.
The content of the invention
The technical problem to be solved in the present invention is the effect of drugs difference for treating insomnia in the prior art and is not conducive to inhale
A kind of the problem of receipts, there is provided medicine for treating insomnia and preparation method thereof.
In order to solve the above-mentioned technical problem, technical scheme provided by the invention is：
A kind of medicine for treating insomnia, the medicine are composed of the following components in parts by weight：
Spina date seed 20-40 parts；Radix Astragali 20-30 parts；Fruit of Chinese magnoliavine 15-20 parts；Polygala 10-15 parts；Root tuber of aromatic turmeric 10-15 parts；Cedar seed
Benevolence 5-8 parts；Pseudo-ginseng 15-20 parts；Cape jasmine 5-8 parts；Dried pinellia 10-15 parts；Radix glycyrrhizae 10-20 parts；Auxiliary material 1-20 parts.
In above-mentioned composition, using spina date seed, the Radix Astragali, the fruit of Chinese magnoliavine, polygala as monarch drug in a prescription, ministerial drug root tuber of aromatic turmeric, the seed of Oriental arborvitae, three are accompanied by
7th, cape jasmine, dried pinellia, help with radix glycyrrhizae, so as to reach treatment and the effect of relieving insomnia.
Wherein spina date seed has nourishing the liver, calming heart, calms the nerves, the effect of arrest sweating.It controls restlessness of asrhenia type and insomnia, palpitation of palpitating with fear, and polydipsia is empty
Sweat.《This warp》：Main trusted subordinate's fever and chills, heresy knot gas gather, painful limbs, arthritis with fixed pain caused by dampness.《Do not record》：Master is vexatious to sleep, and pain, blood turn navel up and down
Let out long, abnormal sweating polydipsia, bowl spares, beneficial irritability, hard muscles and bones, help cloudy gas, make us fertile strong.《Haigoushen》：Cage bar bone wind, fry end and make soup clothes
It.《Bencao Shiyi》：Sleeping more lifes makes, and must not sleep and fry.Wang Haogu：Milk-livered egersis is controlled, is trembled with fear, fries clothes；Somnolence due to gallbladder-excess is controlled, heat
, it is raw to use.《Collected statements on the herbal foundation》：Hold back gas to calm the nerves, flourish muscle supports marrow, and stomach fortune spleen.《Book on Chinese herbal medicine is new again》：Soothing the liver qi-regulating, moistens the lung and nourish yin, temperature
Middle dampness removing, gas hidroschesis is held back, beneficial will is breathed out surely, hearing-improing and eyesight improving.
The Radix Astragali is sweet, tepor.Return lung, spleen, liver and kidney channel.The medicinal history for having more than 2000 years so far of the Radix Astragali, it has increasing
Strong body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide antibacterial action.
The fruit of Chinese magnoliavine is astringed the lung, and nourshing kidney, is promoted the production of body fluid, and receives sweat, puckery essence.Control the deficiency syndrome of the lung to breath with cough, thirst, spontaneous perspiration, night sweat, internal lesion caused by overexertion is thin
It is thin, emission, protracted dysentery and diarrhea.
The compatibility and ratio of above four traditional Chinese medicine thing are the keys of pharmaceutical composition of the present invention.Preferably, the medicine by
The composition composition of following parts by weight：
40 parts of spina date seed；25 parts of the Radix Astragali；20 parts of the fruit of Chinese magnoliavine；15 parts of polygala；10 parts of root tuber of aromatic turmeric；8 parts of the seed of Oriental arborvitae；20 parts of pseudo-ginseng；
6 parts of cape jasmine；12 parts of dried pinellia；20 parts of radix glycyrrhizae；20 parts of auxiliary material.
The preparation of Chinese medicine composition of the present invention is freeze dried powder, therefore in order to improve the mouthfeel of medicine, preferably, at this
In one embodiment of invention, the Chinese medicine composition also includes sweetener and/or flavouring agent.
In the present invention, the effect of selection of auxiliary material is final to preparation also functions to important function.Preferably, the auxiliary material
For one kind in mannitol, phosphate, glycine, lysine, albumin, DLPC, cholesterol or
It is several.
Present invention also offers a kind of preparation method of said medicine, comprise the following steps：
Step 1) spina date seed, the Radix Astragali, the fruit of Chinese magnoliavine, polygala, root tuber of aromatic turmeric, the seed of Oriental arborvitae, pseudo-ginseng, cape jasmine, dried pinellia and radix glycyrrhizae difference
Extracted 3~5 hours using alcohol extracting method, obtain respective extract；
Step 2) mixes extract made from step 1 with auxiliary material, dries, drug powder is obtained after smashing；
The drug powder that step 3) obtains step 3 is placed in household freezer, is freezed at -40 DEG C 1.5~2 hours, at this
At a temperature of crush, dry, obtain freeze-dried powder；
The freeze-dried powder that step 4) obtains step 3) loads packaging, obtains the medicine.
Preferably, the condition of the step 1) alcohol extracting method is：The spina date seed, the Radix Astragali, the fruit of Chinese magnoliavine, polygala are added 5
80% ethanol of times volume extracts 5 hours；The root tuber of aromatic turmeric, the seed of Oriental arborvitae, pseudo-ginseng, cape jasmine, dried pinellia and radix glycyrrhizae are added into 10 times of bodies
65% long-pending ethanol extracts 8 hours.
It is highly preferred that step 1) is described to be extracted as refluxing extraction, number is 3 times.
Preferably, the step 3) time freezed is 1.5 hours.
Preferably, the grain diameter of the step 3) freeze-dried powder is less than 10 microns.
Present invention also offers a kind of application method of said medicine, by the powder of the Chinese medicine composition at 50~60 DEG C
Dissolving is taken after mixing it with water in solvent.
Beneficial effects of the present invention are：
The present invention using spina date seed, the Radix Astragali, the fruit of Chinese magnoliavine, polygala as monarch drug in a prescription, be accompanied by ministerial drug root tuber of aromatic turmeric, the seed of Oriental arborvitae, pseudo-ginseng, cape jasmine,
Dried pinellia, help with radix glycyrrhizae, so as to reach treatment and the effect of relieving insomnia.
Embodiment
The invention discloses a kind of medicine for treating insomnia and preparation method thereof.Those skilled in the art can use for reference herein
Content, it is suitably modified technological parameter realization.It is important to note that all similar replacements and change are to people in the art
It is it will be apparent that they are considered as being included in the present invention for member, and related personnel can substantially not depart from the present invention
Content described herein is modified or suitably changed with combining on the basis of content, spirit and scope, come realize and using this
Inventive technique.
In the present invention, unless otherwise stated, Science and Technology noun used herein has art technology
The implication that personnel are generally understood that.
In order that those skilled in the art more fully understands technical scheme, with reference to specific embodiment pair
The present invention is described in further detail.
Embodiment 1：Pharmaceutical composition
The medicine is composed of the following components in parts by weight：
40 parts of spina date seed；25 parts of the Radix Astragali；20 parts of the fruit of Chinese magnoliavine；15 parts of polygala；10 parts of root tuber of aromatic turmeric；8 parts of the seed of Oriental arborvitae；20 parts of pseudo-ginseng；
6 parts of cape jasmine；12 parts of dried pinellia；20 parts of radix glycyrrhizae；20 parts of auxiliary material.
Embodiment 2：Pharmaceutical composition
The medicine is composed of the following components in parts by weight：
20 parts of spina date seed；20 parts of the Radix Astragali；15 parts of the fruit of Chinese magnoliavine；10 parts of polygala；10 parts of root tuber of aromatic turmeric；5 parts of the seed of Oriental arborvitae；15 parts of pseudo-ginseng；
5 parts of cape jasmine；10 parts of dried pinellia；10 parts of radix glycyrrhizae；1 part of auxiliary material.
Embodiment 3：Pharmaceutical composition
The medicine is composed of the following components in parts by weight：
40 parts of spina date seed；30 parts of the Radix Astragali；20 parts of the fruit of Chinese magnoliavine；15 parts of polygala；15 parts of root tuber of aromatic turmeric；8 parts of the seed of Oriental arborvitae；20 parts of pseudo-ginseng；
8 parts of cape jasmine；15 parts of dried pinellia；20 parts of radix glycyrrhizae；20 parts of auxiliary material.
Embodiment 4：Prepare embodiment
Take 40 parts of spina date seed；25 parts of the Radix Astragali；20 parts of the fruit of Chinese magnoliavine；15 parts of polygala, is cleaned respectively, is separately added into 5 times of volumes
In 80% ethanol, refluxing extraction 3 times, 5 hours every time, respective extract is obtained.
Take 10 parts of root tuber of aromatic turmeric；8 parts of the seed of Oriental arborvitae；20 parts of pseudo-ginseng；6 parts of cape jasmine；12 parts of dried pinellia；20 parts of radix glycyrrhizae, cleans respectively, point
Refluxing extraction 3 times, 8 hours every time, respective extract Jia Ru not be obtained in 10 times of ethanol of volume 65%.
Said extracted thing is mixed, 20 parts of auxiliary materials is added, dry, pulverize, obtain drug powder.
Said medicine powder is placed in household freezer, freezes at -40 DEG C 1.5 hours, crushes at such a temperature, is dried,
Freeze-dried powder is obtained, the grain diameter of the freeze-dried powder is 10 microns.
Above-mentioned mixed-powder is loaded and packed, obtains the medicine.
Embodiment 5：Prepare embodiment
Take 20 parts of spina date seed；20 parts of the Radix Astragali；15 parts of the fruit of Chinese magnoliavine；10 parts of polygala, is cleaned respectively, is separately added into 5 times of volumes
In 80% ethanol, refluxing extraction 3 times, 5 hours every time, respective extract is obtained.
Take 10 parts of root tuber of aromatic turmeric；5 parts of the seed of Oriental arborvitae；15 parts of pseudo-ginseng；5 parts of cape jasmine；10 parts of dried pinellia；10 parts of radix glycyrrhizae, cleans respectively, point
Refluxing extraction 3 times, 8 hours every time, respective extract Jia Ru not be obtained in 10 times of ethanol of volume 65%.
Said extracted thing is mixed, 1 part of auxiliary material is added, dry, pulverize, obtain drug powder.
Said medicine powder is placed in household freezer, freezes at -40 DEG C 2 hours, crushes at such a temperature, dries, obtains
To freeze-dried powder, the grain diameter of the freeze-dried powder is 8 microns.
Above-mentioned freeze-dried powder is loaded and packed, obtains the medicine.
Embodiment 6：Prepare embodiment
Take 40 parts of spina date seed；30 parts of the Radix Astragali；20 parts of the fruit of Chinese magnoliavine；15 parts of polygala, is cleaned respectively, is separately added into 5 times of volumes
In 80% ethanol, refluxing extraction 3 times, 5 hours every time, respective extract is obtained.
Take 15 parts of root tuber of aromatic turmeric；8 parts of the seed of Oriental arborvitae；20 parts of pseudo-ginseng；8 parts of cape jasmine；15 parts of dried pinellia；20 parts of radix glycyrrhizae, cleans respectively, point
Refluxing extraction 3 times, 8 hours every time, respective extract Jia Ru not be obtained in 10 times of ethanol of volume 65%.
Said extracted thing is mixed, 20 parts of auxiliary materials is added, dry, pulverize, obtain drug powder.
Said medicine powder is placed in household freezer, freezes at -40 DEG C 2 hours, crushes at such a temperature, dries, obtains
To freeze-dried powder, the grain diameter of the freeze-dried powder is 8 microns.
Above-mentioned freeze-dried powder is loaded and packed, obtains the medicine.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (10)
1. a kind of medicine for treating insomnia, it is characterised in that the medicine is composed of the following components in parts by weight：
Spina date seed 20-40 parts；Radix Astragali 20-30 parts；Fruit of Chinese magnoliavine 15-20 parts；Polygala 10-15 parts；Root tuber of aromatic turmeric 10-15 parts；Seed of Oriental arborvitae 5-8
Part；Pseudo-ginseng 15-20 parts；Cape jasmine 5-8 parts；Dried pinellia 10-15 parts；Radix glycyrrhizae 10-20 parts；Auxiliary material 1-20 parts.
2. medicine according to claim 1, it is characterised in that the medicine is composed of the following components in parts by weight：
40 parts of spina date seed；25 parts of the Radix Astragali；20 parts of the fruit of Chinese magnoliavine；15 parts of polygala；10 parts of root tuber of aromatic turmeric；8 parts of the seed of Oriental arborvitae；20 parts of pseudo-ginseng；Cape jasmine 6
Part；12 parts of dried pinellia；20 parts of radix glycyrrhizae；20 parts of auxiliary material.
3. medicine according to claim 1, it is characterised in that the auxiliary material be selected from mannitol, phosphate, glycine,
One or more in lysine, albumin, DLPC, cholesterol.
4. medicine according to claim 1, it is characterised in that the medicine also includes sweetener and/or flavouring agent.
5. the preparation method of a kind of medicine as described in claim 1-4 any one, it is characterised in that comprise the following steps：
Step 1) spina date seed, the Radix Astragali, the fruit of Chinese magnoliavine, polygala, root tuber of aromatic turmeric, the seed of Oriental arborvitae, pseudo-ginseng, cape jasmine, dried pinellia and radix glycyrrhizae are utilized respectively
Alcohol extracting method extracts 3~5 hours, obtains respective extract；
Step 2) mixes extract made from step 1 with auxiliary material, dries, drug powder is obtained after smashing；
The drug powder that step 3) obtains step 3 is placed in household freezer, is freezed at -40 DEG C 1.5~2 hours, in the temperature
Lower crushing, dry, obtain freeze-dried powder；
The freeze-dried powder that step 4) obtains step 3) loads packaging, obtains the medicine.
6. preparation method according to claim 5, it is characterised in that the condition of the step 1) alcohol extracting method is：By described in
80% ethanol that spina date seed, the Radix Astragali, the fruit of Chinese magnoliavine, polygala add 5 times of volumes extracts 5 hours；By the root tuber of aromatic turmeric, the seed of Oriental arborvitae, pseudo-ginseng,
65% ethanol that cape jasmine, dried pinellia and radix glycyrrhizae add 10 times of volumes extracts 8 hours.
7. preparation method according to claim 6, it is characterised in that step 1) is described to be extracted as refluxing extraction, number 3
It is secondary.
8. preparation method according to claim 5, it is characterised in that the step 3) time freezed is 1.5 hours.
9. preparation method according to claim 5, it is characterised in that the grain diameter of the step 3) freeze-dried powder is 10
Micron is following.
10. a kind of application method of medicine as claimed in claim 1, it is characterised in that by the powder of the Chinese medicine composition
Dissolve and take after mixing it with water in 50~60 DEG C of solvents.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610767382.XA CN107773730A (en) | 2016-08-30 | 2016-08-30 | A kind of medicine for treating insomnia and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610767382.XA CN107773730A (en) | 2016-08-30 | 2016-08-30 | A kind of medicine for treating insomnia and preparation method thereof |
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| CN107773730A true CN107773730A (en) | 2018-03-09 |
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| CN201610767382.XA Pending CN107773730A (en) | 2016-08-30 | 2016-08-30 | A kind of medicine for treating insomnia and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109700973A (en) * | 2019-02-28 | 2019-05-03 | 何原 | A kind of regenerated Chinese medicine composition of promotion Hippocampal Neuron Cells |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100998664A (en) * | 2006-12-31 | 2007-07-18 | 柴增胜 | Oral traditional Chinese medicine for treating critical anhypnia of insulfficiency of the spleen-qi type |
| CN102058566A (en) * | 2010-12-24 | 2011-05-18 | 中国药科大学 | Dry powder inhaler with constituent rubescensin A as well as preparation method and application thereof |
| CN103816332A (en) * | 2013-12-10 | 2014-05-28 | 济南新起点医药科技有限公司 | Traditional Chinese medicine composition for treating insomnia caused by weakness of both heart and spleen |
| CN105412612A (en) * | 2015-12-02 | 2016-03-23 | 天津太平洋制药有限公司 | Medicine for treating insomnia |
-
2016
- 2016-08-30 CN CN201610767382.XA patent/CN107773730A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100998664A (en) * | 2006-12-31 | 2007-07-18 | 柴增胜 | Oral traditional Chinese medicine for treating critical anhypnia of insulfficiency of the spleen-qi type |
| CN102058566A (en) * | 2010-12-24 | 2011-05-18 | 中国药科大学 | Dry powder inhaler with constituent rubescensin A as well as preparation method and application thereof |
| CN103816332A (en) * | 2013-12-10 | 2014-05-28 | 济南新起点医药科技有限公司 | Traditional Chinese medicine composition for treating insomnia caused by weakness of both heart and spleen |
| CN105412612A (en) * | 2015-12-02 | 2016-03-23 | 天津太平洋制药有限公司 | Medicine for treating insomnia |
Non-Patent Citations (3)
| Title |
|---|
| 尹莹: "中医综合疗法辨证分型治疗失眠的临床观察", 《湖北中医杂志》 * |
| 施金凤: "自拟安神汤加减治疗失眠96例", 《中医药临床杂志》 * |
| 高红勤等: "胡铁城教授治疗老年失眠经验介绍", 《新中医》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109700973A (en) * | 2019-02-28 | 2019-05-03 | 何原 | A kind of regenerated Chinese medicine composition of promotion Hippocampal Neuron Cells |
| CN109700973B (en) * | 2019-02-28 | 2021-06-22 | 何原 | Traditional Chinese medicine composition for promoting regeneration of hippocampal neuronal cells |
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Application publication date: 20180309 |