CN107753810A - 一种用于防治心血管疾病的槐米口服液及其制备方法 - Google Patents

一种用于防治心血管疾病的槐米口服液及其制备方法 Download PDF

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CN107753810A
CN107753810A CN201711198187.0A CN201711198187A CN107753810A CN 107753810 A CN107753810 A CN 107753810A CN 201711198187 A CN201711198187 A CN 201711198187A CN 107753810 A CN107753810 A CN 107753810A
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oral liquid
cure
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sophora bud
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付平国
刘文瑞
欧玉莲
王建买
付嫦娥
刘小军
欧召国
付玉香
李凯
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Hengyang Huashengda Forestry Science And Technology Co Ltd
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Abstract

一种用于防治心血管疾病的槐米口服液,按照质量份数，由以下成分制成:槐米100份、白芍5‑15份、土茯苓15‑25份、芹菜籽5‑15份、佛手20‑30份、麦芽45‑60份、益母草5‑15份、蒲公英5‑15份、绞股蓝3‑10份、连翘5‑15份、茯神10‑20份、槐花10‑20份、牛膝25‑35份、锦灯笼5‑15份、杜仲叶5‑15份、北柴胡3‑10份、鸡屎藤25‑35份、丹参50‑70份、甘草10‑20份、荠菜3‑10份、桑叶5‑10份。该槐米口服液适应于：高血压、高血脂患者，心脏病患者，脑中风后遗症患者等。

Description

一种用于防治心血管疾病的槐米口服液及其制备方法
技术领域
本发明属于中药技术领域，具体涉及一种防治心血管疾病的槐米口服液及其制备方法。
背景技术
在中国槐树有家槐、针叶槐、黄槐、豆槐、金槐等近二十种，以金槐为最好，因颜色呈金黄色而得名，其株产量最大，芦丁含量最高，米粒大而实，所以被公认为槐米中之上品。
金槐全株均可入药，槐米为清凉性收剑止血药，并降血压；果清热、润肝、凉血、止血。槐米为槐树的干燥花或花蕾，夏季花将开放采摘，晒干后收储，可供全年使用。槐米具有凉血止血，清肝泻火的功能；临床多用于便血、痔血、血痢、崩漏、吐血等症的治疗。
由于槐米对毛细血管的作用，能保持毛细血管正常的抵抗力，减少血管通透性，可使血管因脆性增加而出血的毛细血管恢复正常弹性，故有软化血管、增加血管弹性，对动脉硬化有软化作用，对糖尿病、视网膜炎有防治作用；其制剂有促进微循环、降脂降压、能效降低肝、主动脉及血中胆固醇含量对肥胖者有降脂减肥作用；由于具有上述作用，古今皆知，李时珍《木草纲目》早已记述祖先用槐米的保健功能。
因此，有必要开发一种用于防治心血管疾病的槐米口服液。
发明内容
本发明的目的之一是克服现有技术的上述不足而提供一种用于防治心血管疾病的槐米口服液, 该槐米口服液适应于：高血压、高血脂患者，心脏病患者，脑中风后遗症患者等。
本发明的目的之二在于提供上述用于防治心血管疾病的槐米口服液的制备方法。
本发明的技术方案是：一种用于防治心血管疾病的槐米口服液，以重量分数计，由以下成分制成：槐米100份、白芍5-15份、土茯苓15-25份、芹菜籽5-15份、佛手20-30份、麦芽45-60份、益母草5-15份、蒲公英5-15份、绞股蓝3-10份、连翘5-15份、茯神10-20份、槐花10-20份、牛膝25-35份、锦灯笼5-15份、杜仲叶5-15份、北柴胡3-10份、鸡屎藤25-35份、丹参50-70份、甘草10-20份、荠菜3-10份、桑叶5-10份。
其中所述的白芍优选7-10份，所述的土茯苓优选17-22份。
其中所述的芹菜籽优选9-12份，所述的佛手优选23-27份，所述的麦芽优选50-60份，所述的益母草优选9-12份。
其中所述的蒲公英优选9-12份, 所述的绞股蓝优选5-9份，所述的连翘优选9-12份。
其中所述的茯神优选12-17份, 所述的槐花优选12-17份, 所述的牛膝优选27-32份；所述的槐花为笨槐槐花。
其中所述的锦灯笼优选9-12份, 所述的杜仲叶优选5-10份, 所述的北柴胡优选5-9份。
其中所述的鸡屎藤优选27-33份, 所述的丹参优选55-65份, 所述的甘草优选12-17份；
其中所述的荠菜优选5-9份，所述的桑叶优选4-8份。
本发明所述用于防治心血管疾病的槐米口服液的制备方法，依次包括如下步骤：
（1）将原料分别经粉碎、过筛后混匀，得混合料；
（2）将混合料加入2-4 倍重量水，加热至90-100℃煎煮2-4h ；
（3）过滤，滤液收集，滤渣加入3-6倍重量95% 的乙醇水溶液，加热至50-60℃煎煮1-2h；
（4）过滤，合并滤液，滤液浓缩至无醇味，即得用于防治心血管疾病的槐米口服液。
本发明所述用于防治心血管疾病的槐米口服液的使用方法如下：本发明治疗心脑血管病的槐米口服液服用方法如下：每天3次温服，每次20-30ml。
该槐米口服液适应于：高血压、高血脂患者，心脏病患者，脑中风后遗症患者等。
具体实施方式
下面将结合实施例对本发明的实施方案进行详细描述，但是本领域技术人员将会理解，下列实施例仅用于说明本发明，而不应视为限定本发明的范围。
表1、表2、为本发明槐米口服液的实施例配方( 以g 为单位)。
表1
。
表2
。
实施例、对比例所述用于防治心血管疾病的槐米口服液的制备方法，依次包括如下步骤：
（1）将原料分别经粉碎、过筛后混匀，得混合料；
（2）将混合料加入3倍量水，加热至100℃煎煮2h ；
（3）过滤，滤液收集，滤渣加入5倍量95% 的乙醇水溶液，加热至60℃煎煮2h ；
（4）过滤，合并滤液，滤液浓缩至无醇味，即得用于防治心血管疾病的槐米口服液。
临床应用结果：
A组：治疗冠心病人120例，分为12组，每组10人，每组病人分别服用实施例1-10、对比例1-2的口服液，每日3次，每次20mL，饭前40分钟温开水冲服，30天为1个疗程，服用4个疗程。
服药前病人的症状为心慌，气短，憋气，胸口无规律疼痛发作，走路喘气，腿脚无力，心电图显示供血严重不足，服药前平均S-T段下降1.0毫米。
服用4个疗程后冠心病病人的结果见表3。
表3
。
B组：中风瘫痪病人65例，分为13组，每组5人，实施例组病人分别服用实施例1-10、对比例1-2的口服液，每日3次，每次30 mL，中风通片，每日3次，每次500mg，饭前40分钟温开水冲服，中风通片剂前10天每日3次，每次3片，以后每次改服1片），30天为1个疗程，服用6个疗程，对照组仅仅服用中风通片，每日3次，每次3片。
服药前病人症状为神志不清，眼斜口歪，瘫痪卧床。
服用6个疗程后中风瘫痪病人的实验结果见表4。
表4
。
以上内容描述了本发明的基本原理和主要特征，本发明不受上述实施例的限制，在不脱离本发明精神和范围的前提下，本发明还会有各种变化和改进，这些变化和改进都落入要求保护的本发明范围内。

Claims (9)

1.一种用于防治心血管疾病的槐米口服液, 按照质量份数，由以下成分制成: 槐米100份、白芍5-15份、土茯苓15-25份、芹菜籽5-15份、佛手20-30份、麦芽45-60份、益母草5-15份、蒲公英5-15份、绞股蓝3-10份、连翘5-15份、茯神10-20份、槐花10-20份、牛膝25-35份、锦灯笼5-15份、杜仲叶5-15份、北柴胡3-10份、鸡屎藤25-35份、丹参50-70份、甘草10-20份、荠菜3-10份、桑叶5-10份。
2.根据权利要求1所述用于防治心血管疾病的槐米口服液，其特征在于所述的白芍为7-10份，所述的土茯苓为17-22份。
3.根据权利要求1所述用于防治心血管疾病的槐米口服液，其特征在于所述的芹菜籽为9-12份，所述的佛手为23-27份，所述的麦芽为50-60份，所述的益母草为9-12份。
4.根据权利要求1所述用于防治心血管疾病的槐米口服液，其特征在于所述的蒲公英为9-12份, 所述的绞股蓝为5-9份，所述的连翘为9-12份。
5.根据权利要求1所述用于防治心血管疾病的槐米口服液，其特征在于所述的茯神为12-17份, 所述的槐花为12-17份, 所述的牛膝为27-32份。
6.根据权利要求1所述用于防治心血管疾病的槐米口服液，其特征在于所述的锦灯笼为9-12份, 所述的杜仲叶为5-10份, 所述的北柴胡为5-9份。
7.根据权利要求1所述用于防治心血管疾病的槐米口服液，其特征在于所述的鸡屎藤为27-33份, 所述的丹参为55-65份, 所述的甘草为12-17份。
8.根据权利要求1所述用于防治心血管疾病的槐米口服液，其特征在于所述的荠菜为5-9份，所述的桑叶为4-8份。
9.根据权利要求1所述用于防治心血管疾病的槐米口服液的制备方法，其特征在于依次包括如下步骤：
（1）将原料分别经粉碎、过筛后混匀，得混合料；
（2）将混合料加入2-4 倍重量水，加热至90-100℃煎煮2-4h ；
（3）过滤，滤液收集，滤渣加入3-6倍重量95% 的乙醇水溶液，加热至50-60℃煎煮1-2h；
（4）过滤，合并滤液，滤液浓缩至无醇味，即得用于防治心血管疾病的槐米口服液。
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CN102949481A (zh) * 2011-11-07 2013-03-06 沈阳创达技术交易市场有限公司 一种降压降脂保健茶

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CN102949481A (zh) * 2011-11-07 2013-03-06 沈阳创达技术交易市场有限公司 一种降压降脂保健茶

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