CN107753780A - A kind of decoction medicine and preparation method for treating recurrent oral ulceration - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to provide a kind of decoction medicine for treating recurrent oral ulceration according to the understanding mechanism of Chinese traditional treatment recurrent oral ulceration, each component and its mass parts ratio of the medicine are as follows：15~55g of lily, 6~15g of asparagus fern, 6~15g of the wind-weed, 10~18g of glaucousleaf cyclea herb, 6~12g of cape jasmine, 6~15g of the leaf of bamboo, 15~28g of leatherleaf mahonia root, 5~16g of Asian puccoon, 6~15g of moutan bark, 15~35g of japanese oxtongue herb, 6~15g of the radix paeoniae rubrathe, 3~9g of rhizoma typhonii, 3~9g of polyandrous balanophora herb, 8~16g of the root of three-nerved spicebush, 6~15g of the fruit of Chinese wolfberry, 25~60g of Chinese holly bark, 2~7g of the fruit of Chinese magnoliavine, 6~18g of the stem of noble dendrobium, 9~35g of asian tetracera root or leaf；Medicine provided by the invention is a good Chinese prescription.

Description

A kind of decoction medicine and preparation method for treating recurrent oral ulceration

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of decoction medicine for treating recurrent oral ulceration, especially It is the field of the decoction medicine and preparation method used for Blood of Patients with Recurrent Oral.

Background technology

According to the relevant information：Recurrent aphthous ulcer（recurrent oral ulcer）Also known as RAU （recurrent aphthae）, be most common ulcer diseases in oral mucosal disease, the cause of disease is complicated, more with it is immune, hereditary, Systemic disease, infection, environment（Psychology, life, work, social environment）It is relevant etc. factor.Illness rate is typically recognized in crowd For more than 10%, men and women, old and young can be betided, with young and middle-aged most common.Recurrent oral ulceration has self limiting, can with self-healing, Any position of mucous membrane of mouth can be betided, common with lip, cheek, tongue, severe patient can involve pharyngeal mucous membrane.Many patients with The extension of the course of disease, ulcer area increase, number increases, and pain aggravates, and healing stage extends, and interval shortening etc., influences to feed With speak.

Clinical manifestation：

1. minor aphtha：It is sensitive or the congested area of needle point sample size occur from the beginning of lesion, formed in a short time diameter 2~ 4mm, circular or ellipse, the shallow aphtha of clear border.Center micro-pits, surface are covered with one layer of faint yellow pseudomembrane, ulcer week It is in blush shape to enclose mucous membrane hyperemia, and its substrate is laid one's hand on not hard.Ulcer number is generally 2~3.Ulcer has more violent burning after being formed Cusalgia, especially with obvious at the tip of the tongue.When contacting food excitatory more very.Typically without constitutional symptom.

2. rash sample aphtha：Also known as stomatitis type aphtha.This type is except ulcer is small, number is more（Up to 20~30）Outside, it is remaining with it is light The performance of type aphtha is similar.For Sucralfate widely distributed, mucous membrane is congested obvious.Have acutely and with headache, heating, regional nodes The symptoms such as enlargement.

3. periglandular aphtha：Also known as Periadenitis mucous membrane periadenitis or huge aphtha, it is various middle most serious One type.Ulcer often single generation, 2 or more than 2 persons it is rare.Lip inner side and bicker area mucous membrane are apt to occur in, can also be occurred in tongue palate The positions such as bow, soft palate.From the beginning of when ulcer it is identical with minor aphtha, but its diameter is gradually extended to 1~2cm, and to Deep Development To mucous membrane gland.Ulcer can be aubergine, and edge is irregular, is swelled in flap, concavity, and shape is like " crater ".Bottom is uneven, micro- Firmly, in brief summary nodular.Blush is obvious around ulcer.Part has severe pain and can be with whole bodies such as regional glandular enlargement, heatings Symptom.The course of disease is often more than more than the moon, and elder was up to 1 year.Scar is left more afterwards, and severe patient can form tissue defect or deformity.

So, it is art technology with regard to how to find a kind of Chinese medicine composition that can effectively treat recurrent oral ulceration The problem of personnel are urgently to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, on treatment recurrent oral ulceration, people gradually appreciate The advantages of Chinese traditional treatment recurrent oral ulceration, and good effect, advantage, the pin such as quick, toxic side effect is small over the course for the treatment of To the present situation of existing western medical treatment recurrent oral ulceration, the purpose of the present invention is to be to provide one kind to treat recurrent oral and burst The decoction medicine of ulcer, to solve the problems, such as that Blood of Patients with Recurrent Oral is got well early.The medicine is with common Chinese medicine For raw material, by selecting rational medicine and mass parts ratio, above-mentioned recurrent oral ulceration can be effectively treated.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided and treats recurrent oral The decoction medicine and preparation method of ulcer, it is characterised in that each component and mass parts of the medicine are than as follows：

15~55g of lily, 6~15g of asparagus fern, 6~15g of the wind-weed, 10~18g of glaucousleaf cyclea herb, 6~12g of cape jasmine, 6~15g of the leaf of bamboo, thatch It is 15~28g of the coptis, 5~16g of Asian puccoon, 6~15g of moutan bark, 15~35g of japanese oxtongue herb, 6~15g of the radix paeoniae rubrathe, 3~9g of rhizoma typhonii, more 3~9g of stamen Balaenoptera borealis Lesson, 8~16g of the root of three-nerved spicebush, 6~15g of the fruit of Chinese wolfberry, 25~60g of Chinese holly bark, 2~7g of the fruit of Chinese magnoliavine, 6~18g of the stem of noble dendrobium, tin 9~35g of leaf rattan.

A kind of decoction medicine and preparation method for treating recurrent oral ulceration, it is characterised in that the medicine it is each Component and mass parts are than as follows：

18~48g of lily, 7~13g of asparagus fern, 7~13g of the wind-weed, 11~16g of glaucousleaf cyclea herb, 7~11g of cape jasmine, 7~13g of the leaf of bamboo, thatch It is 18~25g of the coptis, 6~14g of Asian puccoon, 7~13g of moutan bark, 18~31g of japanese oxtongue herb, 7~13g of the radix paeoniae rubrathe, 4~8g of rhizoma typhonii, more 4~8g of stamen Balaenoptera borealis Lesson, 9~14g of the root of three-nerved spicebush, 7~13g of the fruit of Chinese wolfberry, 28~52g of Chinese holly bark, 3~6g of the fruit of Chinese magnoliavine, 7~16g of the stem of noble dendrobium, tin 10~31g of leaf rattan.

A kind of decoction medicine and preparation method for treating recurrent oral ulceration, it is characterised in that the medicine it is each Component and mass parts are than as follows：

Lily 42g, asparagus fern 12g, wind-weed 12g, glaucousleaf cyclea herb 14g, cape jasmine 10g, leaf of bamboo 12g, leatherleaf mahonia root 22g, Asian puccoon 13g, tree peony Skin 12g, japanese oxtongue herb 28g, radix paeoniae rubrathe 12g, rhizoma typhonii 7g, polyandrous balanophora herb 7g, root of three-nerved spicebush 13g, fruit of Chinese wolfberry 12g, Chinese holly bark 45g, Fruit of Chinese magnoliavine 5g, stem of noble dendrobium 14g, asian tetracera root or leaf 28g.

A kind of decoction medicine and preparation method for treating recurrent oral ulceration, it is characterised in that methods described is included such as Lower step is prepared：

A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is respectively crushed into coarse according to mass parts ratio and decocts a drug wrapped；

B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 35min, then again by soaked medicine and soak medicine Clarified solution be put into the lump in marmite, injected medicine 65mm cold boiling water carry out first time high heat decoction, wait decoct arrive 15min When, turn slow fire and boil 35 min, leaching decoction；2. the tepor boiling water that medicine 60mm was re-injected in the dregs of a decoction carries out second of intense fire Decoct, when 10min is arrived in decoction, turn slow fire and boil 30 min, leaching decoction；It is condensed into 3. decoction twice is mixed in 50% Decoction 360ml（Milliliter）.

A kind of decoction medicine and preparation method for treating recurrent oral ulceration, it is characterised in that the instructions of taking is： The herb liquid prepared was taken with one day, morning and evening sub-service, dosage 180ml（Milliliter）/ time, half an hour, which is taken advantage of, before meals warmly takes（Avoid Food raw food and maror）.3 days are a course for the treatment of, 2~4 courses for the treatment of of taking medicine, canker sore healing, and symptom disappears.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Lily, nature and flavor：Sweet, slight bitter, it is slightly cold, there is the effect of Yin nourishing and lung moistening, clearing away the heart fire and tranquillizing, coughed long, in phlegm for treating the deficiency of Yin With blood, pyreticosis later stage, waste heat be not clear or feelings will it is unsuccessful caused by dysphoria palpitates with fear, insomnia and dreamful sleep, absent-minded, carbuncle swells, wet sore etc. Disease；

Asparagus fern, nature and flavor：It is sweet, bitter, cold, there is the effect of nourishing yin to moisten dryness, clearing lung-heat are promoted the production of body fluid, for treat dryness of the lung dry cough, pertussis phlegm it is viscous, Dry throat and mouth, dry constipation of intestines；

The wind-weed, nature and flavor：It is bitter, sweet, cold, there is the effect of clearing heat-fire, fluid dryness, for treat fever caused by exogenous pathogenic factors, hyperpyrexia polydipsia, Lung-heat type cough, osteopyrexia and fever, Heat Diabetes, dry constipation of intestines；

Glaucousleaf cyclea herb, nature and flavor：It is bitter, cold, root：The effect of with purge the green, relieving heat toxin, anti-inflammatory, for treat general laryngalgia, diphtheria, Infant fetal toxin, acute toothache；

Cape jasmine, nature and flavor：Cold in nature, bitter, there is the effect of purging intense heat relieving restlessness, reducing fever and causing diuresis, removing pattogenic heat from the blood and toxic material from the body, for treating the pyreticosis heart The diseases such as tired, jaundice, urine are red, blood strangury and dry pain, blood-head tells nosebleed, the outstanding swelling and pain of mesh, pathogenic fire,toxin and furuncles, strain；

The leaf of bamboo, nature and flavor：It is sweet light, cold, have clearing heat and relieving fidgetness, promote the production of body fluid diuresis the effect of, for treat pyreticosis polydipsia, pediatric epilepsy scared, Cough against hematemesis, flushing, oliguria also, aphthous stomatitis tongue boil；

Leatherleaf mahonia root, nature and flavor：It is bitter, cold, it is nontoxic, there is the effect of heat-clearing, purging intense heat, cool blood, removing toxic substances, for treating influenza, hot dysentery, abdomen Rush down, jaundice, haematemesis, conjunctivitis, laryngalgia, toothache, the disease such as furunculosis；

Asian puccoon, nature and flavor：It is sweet, salty, cold, there is the effect of cool blood, promoting blood circulation, removing toxic substances promoting eruption, it is purple for treating blood-heat and toxin exuberance, macula The diseases such as black, measles without adequate eruption, sore, eczema, scald；

Moutan bark, nature and flavor：It is cold in nature, bitter, pungent, there is the effect of clearing heat and cooling blood, blood circulation promoting competent silt, for treat febrile virulent maculae, tell, It is defeated in battle, has blood in stool, hectic fever due to yin labor heat, closed dysmenorrhea, carbuncle sore tumefacting virus, the pain of injury caused by falling and tumbling；

Japanese oxtongue herb, nature and flavor：It is acrid flavour, cool in nature, there is the effect of purging intense heat and detonicating, stasis-dispelling and pain-killing, inducing diuresis to remove edema, it is unknown for treating Pyogenic infections is had a high fever, traumatic injury, belly turgor；

The radix paeoniae rubrathe, nature and flavor：It is bitter, be slightly cold, there is the effect of clearing heat and cooling blood, blood stasis removing analgesic, for treat febrile virulent maculae, hematemesis and epistaxis, Red eye, swell pain, liver-depressed hypochondrium pain, closed dysmenorrhea, { note of the ancient Chinese } lump in the abdomen stomachache, injury from falling down, carbuncle swells sore；

Rhizoma typhonii, nature and flavor：It is pungent, warm, it is poisonous, there is wind-dispelling phlegm, arresting convulsion is jerked, detoxicating and resolving a mass relieve pain the effect of, for treating apoplexy Phlegm is stopped up, mouth eye whirlpool is oblique, the puckery stuttering, phlegm and headache of language, larynx numbness pharyngalgia, lockjaw disease, control scrofula subcutaneous nodule, venomous snake bite outside；

Polyandrous balanophora herb, nature and flavor：It is sweet, mild-natured, there is the effect of enriching yin and nourishing kidney, promoting diuresis for stranguria, for treating deficiency of Yin bleeding, kidney deficiency The deficiency of blood, various gonorrhoeas；

The root of three-nerved spicebush, nature and flavor：It is warm-natured, hide pungent, there is the effect of pleasant analgesic, warming kidney for dispelling cold, for treating chest and abdomen swelling and pain, circulation of vital energy in the wrong direction asthma The illnesss such as urgency, deficiency-cold in the urinary bladder, enuresis frequent micturition, hernia, dysmenorrhoea；

The fruit of Chinese wolfberry, nature and flavor：It is sweet, flat, there is the effect of nourishing liver and kidney, benefiting shrewd head, for treat consumption consumptive loss, soreness of waist and knee joint, Dizziness and tinnitus, Heat Diabetes, blood deficiency chlorosis, blurred vision；

Chinese holly bark, nature and flavor：Slight bitter is sweet, flat, nontoxic, has and mends the illnesss such as strong, the tonifying yin liver and kidney benefiting of waist pin order；

The fruit of Chinese magnoliavine, nature and flavor：It is sour, sweet, warm, there is the effect of restraining astringent or styptic treatment for spontaneous sweating, nourishing generate fluid, kidney calming, for treating void of coughing long Asthma, emission, enuresis frequent micturition, endless diarrhea, spontaneous perspiration, night sweat, injury thirst, feeble pulse of losing heart, Heat Diabetes, palpitation and insomnia；

The stem of noble dendrobium, nature and flavor：It is sweet, be slightly cold, have reinforcing stomach reg fluid, nourishing Yin and clearing heat the effect of, for treat impairment of yin body fluid deficiency, dry polydipsia, Deficiency of food is retched, abnormal heat, mesh are secretly failed to understand after being ill；

Asian tetracera root or leaf, nature and flavor：It is sour, puckery, mild-natured, there is the effect of arresting collape syndrome by astringents, swelling and pain relieving, for treating protracted dysentery and diarrhea, just The diseases such as blood, prolapse of the anus, seminal emission, leukorrhea, the prolapse of uterus, treating swelling and pain by traumatic injury.

Medicine of the present invention is the principle based on Chinese traditional treatment recurrent oral ulceration, from the disease according to recurrent oral ulceration Reason mechanism and pharmacological action are thought：With regard to recurrent oral ulceration, each raw material herbal medicine efficacy in medicine provided by the present invention is total to Play, have good therapeutic effect to above-mentioned disease.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned recurrent oral ulceration, using the formula The medicine effect of preparation is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to the present invention Embodiment be described in further detail：

Embodiment 1：

A kind of decoction medicine for treating recurrent oral ulceration, it is characterised in that each component and mass parts ratio of the medicine It is as follows：

Lily 42g, asparagus fern 12g, wind-weed 12g, glaucousleaf cyclea herb 14g, cape jasmine 10g, leaf of bamboo 12g, leatherleaf mahonia root 22g, Asian puccoon 13g, tree peony Skin 12g, japanese oxtongue herb 28g, radix paeoniae rubrathe 12g, rhizoma typhonii 7g, polyandrous balanophora herb 7g, root of three-nerved spicebush 13g, fruit of Chinese wolfberry 12g, Chinese holly bark 45g, Fruit of Chinese magnoliavine 5g, stem of noble dendrobium 14g, asian tetracera root or leaf 28g.

Embodiment 2：

A kind of decoction medicine for treating recurrent oral ulceration, it is characterised in that each component and mass parts ratio of the medicine It is as follows：

Lily 48g, asparagus fern 13g, wind-weed 13g, glaucousleaf cyclea herb 16g, cape jasmine 11g, leaf of bamboo 13g, leatherleaf mahonia root 25g, Asian puccoon 14g, tree peony Skin 13g, japanese oxtongue herb 31g, radix paeoniae rubrathe 13g, rhizoma typhonii 8g, polyandrous balanophora herb 8g, root of three-nerved spicebush 14g, fruit of Chinese wolfberry 13g, Chinese holly bark 52g, Fruit of Chinese magnoliavine 6g, stem of noble dendrobium 16g, asian tetracera root or leaf 31g.

Embodiment 3：

A kind of decoction medicine for treating recurrent oral ulceration, it is characterised in that each component and mass parts ratio of the medicine It is as follows：

Lily 55g, asparagus fern 15g, wind-weed 15g, glaucousleaf cyclea herb 18g, cape jasmine 12g, leaf of bamboo 15g, leatherleaf mahonia root 28g, Asian puccoon 16g, tree peony Skin 15g, japanese oxtongue herb 35g, radix paeoniae rubrathe 15g, rhizoma typhonii 9g, polyandrous balanophora herb 9g, root of three-nerved spicebush 16g, fruit of Chinese wolfberry 15g, Chinese holly bark 60g, Fruit of Chinese magnoliavine 7g, stem of noble dendrobium 18g, 9~35g of asian tetracera root or leaf.

Model case

Through clinical conditions Blood of Patients with Recurrent Oral totally 1195, the age is 695, only 492 of more than 37 years old For less than 37 years old.1040 to be fully recovered in 1195 patients, effective 119, invalid 36.Total effective rate is up to 97%.

Claims (3)

1. a kind of decoction medicine for treating recurrent oral ulceration, it is characterised in that each component and its quality of the medicine Part is than as follows：

15~55g of lily, 6~15g of asparagus fern, 6~15g of the wind-weed, 10~18g of glaucousleaf cyclea herb, 6~12g of cape jasmine, 6~15g of the leaf of bamboo, thatch It is 15~28g of the coptis, 5~16g of Asian puccoon, 6~15g of moutan bark, 15~35g of japanese oxtongue herb, 6~15g of the radix paeoniae rubrathe, 3~9g of rhizoma typhonii, more 3~9g of stamen Balaenoptera borealis Lesson, 8~16g of the root of three-nerved spicebush, 6~15g of the fruit of Chinese wolfberry, 25~60g of Chinese holly bark, 2~7g of the fruit of Chinese magnoliavine, 6~18g of the stem of noble dendrobium, tin 9~35g of leaf rattan.

2. it is according to claim 1 treatment recurrent oral ulceration decoction medicine, it is characterised in that the medicine it is each Individual component and its mass parts are than as follows：

18~48g of lily, 7~13g of asparagus fern, 7~13g of the wind-weed, 11~16g of glaucousleaf cyclea herb, 7~11g of cape jasmine, 7~13g of the leaf of bamboo, thatch It is 18~25g of the coptis, 6~14g of Asian puccoon, 7~13g of moutan bark, 18~31g of japanese oxtongue herb, 7~13g of the radix paeoniae rubrathe, 4~8g of rhizoma typhonii, more 4~8g of stamen Balaenoptera borealis Lesson, 9~14g of the root of three-nerved spicebush, 7~13g of the fruit of Chinese wolfberry, 28~52g of Chinese holly bark, 3~6g of the fruit of Chinese magnoliavine, 7~16g of the stem of noble dendrobium, tin 10~31g of leaf rattan.

3. the decoction medicine of the treatment recurrent oral ulceration according to claim 1 to 2, it is characterised in that the medicine Each component and its mass parts than as follows：

Lily 42g, asparagus fern 12g, wind-weed 12g, glaucousleaf cyclea herb 14g, cape jasmine 10g, leaf of bamboo 12g, leatherleaf mahonia root 22g, Asian puccoon 13g, tree peony Skin 12g, japanese oxtongue herb 28g, radix paeoniae rubrathe 12g, rhizoma typhonii 7g, polyandrous balanophora herb 7g, root of three-nerved spicebush 13g, fruit of Chinese wolfberry 12g, Chinese holly bark 45g, Fruit of Chinese magnoliavine 5g, stem of noble dendrobium 14g, asian tetracera root or leaf 28g.