CN107753733A - A kind of capsule for building up body for improving immunity and preparation method thereof - Google Patents
A kind of capsule for building up body for improving immunity and preparation method thereof Download PDFInfo
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- CN107753733A CN107753733A CN201711018878.8A CN201711018878A CN107753733A CN 107753733 A CN107753733 A CN 107753733A CN 201711018878 A CN201711018878 A CN 201711018878A CN 107753733 A CN107753733 A CN 107753733A
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- 239000002775 capsule Substances 0.000 title claims abstract description 27
- 230000036039 immunity Effects 0.000 title claims abstract description 20
- 238000002360 preparation method Methods 0.000 title claims description 8
- 241000208340 Araliaceae Species 0.000 claims abstract description 18
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 18
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 18
- 235000008434 ginseng Nutrition 0.000 claims abstract description 18
- 240000006079 Schisandra chinensis Species 0.000 claims abstract description 15
- 240000002948 Ophiopogon intermedius Species 0.000 claims abstract description 14
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 11
- 239000009636 Huang Qi Substances 0.000 claims abstract description 9
- 239000003814 drug Substances 0.000 claims abstract description 7
- 238000000605 extraction Methods 0.000 claims abstract description 6
- 229940079593 drug Drugs 0.000 claims abstract description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 25
- 238000001914 filtration Methods 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 239000000284 extract Substances 0.000 claims description 9
- 238000010992 reflux Methods 0.000 claims description 6
- 235000008422 Schisandra chinensis Nutrition 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 6
- 239000000843 powder Substances 0.000 description 8
- PJANXHGTPQOBST-VAWYXSNFSA-N Stilbene Natural products C=1C=CC=CC=1/C=C/C1=CC=CC=C1 PJANXHGTPQOBST-VAWYXSNFSA-N 0.000 description 5
- 230000035755 proliferation Effects 0.000 description 5
- 210000000952 spleen Anatomy 0.000 description 5
- PJANXHGTPQOBST-UHFFFAOYSA-N stilbene Chemical compound C=1C=CC=CC=1C=CC1=CC=CC=C1 PJANXHGTPQOBST-UHFFFAOYSA-N 0.000 description 5
- 235000021286 stilbenes Nutrition 0.000 description 5
- 239000000706 filtrate Substances 0.000 description 4
- 238000003304 gavage Methods 0.000 description 4
- 210000004698 lymphocyte Anatomy 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- LAZPBGZRMVRFKY-HNCPQSOCSA-N Levamisole hydrochloride Chemical compound Cl.C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 LAZPBGZRMVRFKY-HNCPQSOCSA-N 0.000 description 3
- 230000000052 comparative effect Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000037396 body weight Effects 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 229960003734 levamisole hydrochloride Drugs 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 210000004243 sweat Anatomy 0.000 description 2
- HBOMLICNUCNMMY-KJFJCRTCSA-N 1-[(4s,5s)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Chemical compound O=C1NC(=O)C(C)=CN1C1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-KJFJCRTCSA-N 0.000 description 1
- 238000012449 Kunming mouse Methods 0.000 description 1
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical group C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- AZHSSKPUVBVXLK-UHFFFAOYSA-N ethane-1,1-diol Chemical compound CC(O)O AZHSSKPUVBVXLK-UHFFFAOYSA-N 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000000527 lymphocytic effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000003393 splenic effect Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000003809 water extraction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to field of traditional Chinese, specifically provides a kind of capsule for building up body for improving immunity, is prepared by the bulk drug extraction of following parts by weight：Ginseng 750g, Radix Astragali 750g, tuber of dwarf lilyturf 500g, fruit of Chinese magnoliavine 250g, wherein reusing ginseng, it is found that it improves the effect of immunity and greatly increased.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicine preparation, and in particular to a kind of capsule for building up body for improving immunity and its preparation side
Method.
Background technology
Capsule for building up body is recorded in hygienic ministerial standard, and coarse powder is ground into by ginseng 75g, fruit of Chinese magnoliavine 250g, adds 70% ethanol to return
Stream extraction three times, 2.5 hours every time, merges extract solution, filtration, filtrate is concentrated into the thick paste that relative density is 1.3-1.5, the dregs of a decoction
Add water to cook three times, 2 hours every time, collecting decoction, filter with Radix Astragali 750g, tuber of dwarf lilyturf 500g, filtrate is concentrated into relative density and is
1.1-1.15 clear cream, ethanol is added alcohol content stand at low temperature 24 hours, filtration, is reclaimed ethanol up to 60%, is concentrated into relatively close
The thick paste for 1.25-1.35 is spent, is merged with above-mentioned fruit of Chinese magnoliavine thick paste, adds ginseng fine powder, mixes, dry, pulverize into fine powder, is filled
Enter capsule, produce.Tonifying Qi benefit is cloudy, strengthening exterior and reducing sweat, promotes the production of body fluid to quench thirst, empty for having a delicate constitution caused by deficiency of both qi and yin, palpitation
Sweat is thirsty, the disease such as spiritlessness and weakness.Find that the effect of its raising immunity is not very good during Clinical practice, and existing skill
Art is using the method crushed and decocting is boiled, and technique is coarse, falls behind, and impurity is more, causes patient's dosage excessive, it has not been convenient to take, sternly
This product is have impact on again clinically to apply.
The content of the invention
Goal of the invention：The present inventor reuses ginseng in long-term clinical research, has been surprisingly found that it improves the effect of immunity
Fruit substantially increases.
In order to solve the above problems, it is an object of the invention to a kind of capsule for building up body for improving immunity and its preparation side
Method.
Technical scheme：The purpose of the present invention is realized by following scheme：
A kind of capsule for building up body for improving immunity, it is prepared by the bulk drug extraction of following parts by weight：Ginseng 750g, Huang
Stilbene 750g, tuber of dwarf lilyturf 500g, fruit of Chinese magnoliavine 250g.
The capsule for building up body for improving immunity, preparation method comprise the following steps：Take ginseng, the Huang of corresponding parts by weight
Stilbene, the tuber of dwarf lilyturf and schisandra chinensis medicinal material, extracted 1.5 hours, extracted 2 times with the 6-10 times of 70%-95% measured alcohol reflux, filtration,
It is concentrated under reduced pressure, obtains alcohol-extracted extract；The dregs of a decoction after alcohol extracting are boiled 1 hour with the 6-10 times of decocting measured, extracted 2 times, filtration, are depressurized dense
Contracting, obtains the water extracted immersing paste；Merge alcohol extracting and the water extracted immersing paste, be dried under reduced pressure, mix, encapsulating capsule, produce capsule for building up body.
Application of the capsule for building up body for improving immunity in immunity medicine is improved.
Beneficial effect：In the prior art, it is found that the effect of its raising immunity is not very good, by reusing ginseng transformation
Afterwards, it is found that it improves the positive effect of immunity increase.
Embodiment
Form by the following examples, the above of the present invention is described in further detail again, but should not be by this
The scope for being interpreted as the above-mentioned theme of the present invention is only limitted to following example, and all technologies for being realized based on the above of the present invention are equal
Belong to the scope of the present invention.
Embodiment 1：Take ginseng 750g, Radix Astragali 750g, tuber of dwarf lilyturf 500g, fruit of Chinese magnoliavine 250g, ginseng, the Huang of corresponding parts by weight
Stilbene, the tuber of dwarf lilyturf and schisandra chinensis medicinal material, extracted 1.5 hours, extracted 2 times with 95% alcohol reflux of 6 times of amounts, filtration, is concentrated under reduced pressure,
Obtain alcohol-extracted extract；The dregs of a decoction after alcohol extracting are boiled 1 hour with the decocting of 6 times of amounts, is extracted 2 times, filtration, is concentrated under reduced pressure, obtains the water extracted immersing paste；
Merge alcohol extracting and the water extracted immersing paste, be dried under reduced pressure, mix, encapsulating capsule, produce capsule for building up body.
Embodiment 2：Take ginseng 750g, Radix Astragali 750g, tuber of dwarf lilyturf 500g, fruit of Chinese magnoliavine 250g, ginseng, the Huang of corresponding parts by weight
Stilbene, the tuber of dwarf lilyturf and schisandra chinensis medicinal material, extracted 1.5 hours, extracted 2 times with 70% alcohol reflux of 10 times of amounts, filtration, depressurized dense
Contracting, obtains alcohol-extracted extract；The dregs of a decoction after alcohol extracting are boiled 1 hour with the decocting of 10 times of amounts, is extracted 2 times, filtration, is concentrated under reduced pressure, obtains water extraction
Medicinal extract；Merge alcohol extracting and the water extracted immersing paste, be dried under reduced pressure, mix, encapsulating capsule, produce capsule for building up body.
Embodiment 3：Take ginseng 750g, Radix Astragali 750g, tuber of dwarf lilyturf 500g, fruit of Chinese magnoliavine 250g, ginseng, the Huang of corresponding parts by weight
Stilbene, the tuber of dwarf lilyturf and schisandra chinensis medicinal material, extracted 1.5 hours, extracted 2 times with 85% alcohol reflux of 8 times of amounts, filtration, is concentrated under reduced pressure,
Obtain alcohol-extracted extract；The dregs of a decoction after alcohol extracting are boiled 1 hour with the decocting of 8 times of amounts, is extracted 2 times, filtration, is concentrated under reduced pressure, obtains the water extracted immersing paste；
Merge alcohol extracting and the water extracted immersing paste, be dried under reduced pressure, mix, encapsulating capsule, produce capsule for building up body.
Comparative example 1：Ginseng 75g, Radix Astragali 750g, tuber of dwarf lilyturf 500g, fruit of Chinese magnoliavine 250g are taken, ginseng, Fructus Schisandrae Chinensis powder are broken into
Coarse powder, add the extraction of 70% alcohol reflux three times, 2.5 hours every time, merge extract solution, filtration, filtrate is concentrated into relative density and is
1.3-1.5 thick paste, the dregs of a decoction add water to cook three times with the Radix Astragali, the tuber of dwarf lilyturf, 2 hours every time, collecting decoction, filtration, and filtrate is concentrated into
Relative density is 1.1-1.15 clear cream, adds ethanol alcohol content stand at low temperature 24 hours, is filtered, recovery ethanol is dense up to 60%
The thick paste that relative density is 1.25-1.35 is reduced to, is merged with above-mentioned fruit of Chinese magnoliavine thick paste, adds ginseng fine powder, is mixed, is dried, powder
Fine powder is broken into, loads capsule, produces.
Embodiment 4：The present invention improves the pharmacodynamic study of immunity
Experiment purpose：The capsule for building up body prepared with the embodiment of the present invention 3 is test group, is prepared with comparative example 1 strong
Body capsule is control group, and gavage mouse 30d, levamisole hydrochloride are positive drug group respectively, more of the present invention group, control group and just
Often group mouse is increased by the difference of the ConA splenic lymphocyte proliferations induced to judge whether the present invention strengthens spleen lymphocyte
Grow.
Experimental animal：Kunming mouse, male, body weight 18-22g, our company provide.
Experimental agents：Prepared by the preparation method of above-described embodiment 3 and comparative example 1.
Experimental procedure：Mouse, it is grouped by body weight stratified random, every group 10.It is as shown in the table, the feedwater of normal group gavage；
Levamisole hydrochloride group gavage levamisole hydrochloride；The test group of embodiment 3, control group difference gavage 2gkg-1, each group continuously fills
30d is administered in stomach.Sterile to take spleen, according to individual cells suspension is conventionally produced, adjustment cell concentration is 5 × 105Individual/mL.Spleen is thin
Born of the same parents' suspension is added in 24 orifice plates, and per hole 1mL, every animal sets two multiple holes, and a hole, which is normally cultivated, (adds 50uL PRMI1640
Nutrient solution)；One hole adds 50uL concanavalin As (ConA) liquid (final concentration of 4.76ug/mL).It is placed in 5%CO2, 37 DEG C of CO2Incubator
Middle culture 48h.Experiment terminates preceding 4h, and supernatant 700uL is sucked per hole, adds the PRMI1640 that 700uL is free of hyclone
Nutrient solution, while every hole adds 50uL 5mg/mL MTT liquid.After culture terminates, add 1mL acid isopropyl alcohol per hole, careful piping and druming
Uniformly all dissolved to the crystallization of purple.It is dispensed into before detection in 96 well culture plates, makees 4 multiple holes per hole, at 570nm wavelength
Determine its OD value.
Experimental result：
The present invention to spleen lymphocyte proliferation influence (N=12)
| Group | Dosage (g/kg) | Lymphocytic proliferation rate | Proliferation rate conversion values (X) |
| Normal group | --- | 0.359±0.213 | 0.357±0.073 |
| Levamisol group | 0.008 | 0.452±0.047 | 0.756±0.084★★ |
| 3 groups of embodiment | 2 | 0.697±0.032△△ | 0.896±0.165△△ |
| Control group | 2 | 0.531±0.041 | 0.612±0.041 |
Note：Compared with normal group★★P ＜ 0.01,★P ＜ 0.05；Compared with control group△△P ＜ 0.01,△P ＜ 0.05.
Conclusion：Proliferation rate after 3 groups of capsule for building up body mouse spleen lymphocytes of the embodiment of the present invention are induced by ConA converts
Value is higher than normal group mouse, and effect is better than control group, illustrates that the present invention has relative to control group and significantly improves immunity
Effect.
Claims (3)
1. a kind of capsule for building up body for improving immunity, it is characterised in that be prepared by the bulk drug extraction of following parts by weight：People
Join 750g, Radix Astragali 750g, tuber of dwarf lilyturf 500g, fruit of Chinese magnoliavine 250g.
2. the capsule for building up body of immunity is improved according to claim 1, it is characterised in that preparation method comprises the following steps：
Ginseng, the Radix Astragali, the tuber of dwarf lilyturf and the schisandra chinensis medicinal material of corresponding parts by weight are taken, is extracted with the 6-10 times of 70%-95% measured alcohol reflux
1.5 hours, extract 2 times, filtration, be concentrated under reduced pressure, obtain alcohol-extracted extract；The dregs of a decoction after alcohol extracting are boiled 1 hour with the 6-10 times of decocting measured,
Extraction 2 times, filtration, is concentrated under reduced pressure, obtains the water extracted immersing paste；Merge alcohol extracting and the water extracted immersing paste, be dried under reduced pressure, mix, encapsulating capsule, produce
Capsule for building up body.
3. application of the capsule for building up body of immunity in immunity medicine is improved is improved according to claim 1.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711018878.8A CN107753733A (en) | 2017-10-27 | 2017-10-27 | A kind of capsule for building up body for improving immunity and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711018878.8A CN107753733A (en) | 2017-10-27 | 2017-10-27 | A kind of capsule for building up body for improving immunity and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
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| CN107753733A true CN107753733A (en) | 2018-03-06 |
Family
ID=61271625
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| CN201711018878.8A Withdrawn CN107753733A (en) | 2017-10-27 | 2017-10-27 | A kind of capsule for building up body for improving immunity and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114504055A (en) * | 2022-03-11 | 2022-05-17 | 浙江华腾牧业有限公司 | Feed additive composition without antibiotic addition and pig feed |
Citations (3)
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|---|---|---|---|---|
| CN1682923A (en) * | 2005-03-08 | 2005-10-19 | 北京正大绿洲医药科技有限公司 | Body strengthening dripping pill for invigorating qi and refreshing and its preparing method |
| CN102258679A (en) * | 2011-07-08 | 2011-11-30 | 史国兵 | Traditional Chinese medicine composition and preparation method and application thereof |
| CN104922447A (en) * | 2015-07-19 | 2015-09-23 | 吉林省正和药业集团股份有限公司 | Health improvement capsule preparation method and application |
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2017
- 2017-10-27 CN CN201711018878.8A patent/CN107753733A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1682923A (en) * | 2005-03-08 | 2005-10-19 | 北京正大绿洲医药科技有限公司 | Body strengthening dripping pill for invigorating qi and refreshing and its preparing method |
| CN102258679A (en) * | 2011-07-08 | 2011-11-30 | 史国兵 | Traditional Chinese medicine composition and preparation method and application thereof |
| CN104922447A (en) * | 2015-07-19 | 2015-09-23 | 吉林省正和药业集团股份有限公司 | Health improvement capsule preparation method and application |
Non-Patent Citations (1)
| Title |
|---|
| 金芬芬等: "不同提取方法对黄茂多糖提取率影响的实验研究", 《中华中医药学刊》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114504055A (en) * | 2022-03-11 | 2022-05-17 | 浙江华腾牧业有限公司 | Feed additive composition without antibiotic addition and pig feed |
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