CN107714941A - A kind of Chinese medicine composition for acne, the facial mask prepared and its preparation and application - Google Patents
A kind of Chinese medicine composition for acne, the facial mask prepared and its preparation and application Download PDFInfo
- Publication number
- CN107714941A CN107714941A CN201711007213.7A CN201711007213A CN107714941A CN 107714941 A CN107714941 A CN 107714941A CN 201711007213 A CN201711007213 A CN 201711007213A CN 107714941 A CN107714941 A CN 107714941A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- acne
- radix
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/748—Oldenlandia or Hedyotis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Birds (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of Chinese medicine composition for acne, the facial mask prepared and its preparation and application.Include following component provided by the present invention for the Chinese medicine composition of acne：The Radix Astragali, radix scutellariae, rheum officinale, the bighead atractylodes rhizome, the root of Dahurain angelica, the bletilla striata, radix cynanchi atrati, radix ampelopsis, PORIA ALBA, oldenlandia diffusa, the red sage root；Each component is mixed, water is added, stirs into uniform pasty state and produce face mask of traditional Chinese medicine；Face mask of traditional Chinese medicine is coated on affected part, gone after 20 40min with 20 40 DEG C of washing, daily to coat 1 time, continuous coating at least 4 weeks.At present, this research newly there is no relevant report through looking into, and the present invention provides new method simple and easy to do, economic, practical, easy to spread for treatment acne；The mechanism of present invention treatment acne is to absorb drug percutaneous skin by the transdermal drug delivery system of skin surface, can avoid first pass effect, make medicine persistent and adverse reaction is slight, is advantageous to Chinese medicine various composition and plays curative effect.
Description
Technical field
The invention belongs to dermatology field, and in particular to a kind of Chinese medicine composition for acne, the facial mask prepared and
Its preparation and application.
Background technology
Acne is a kind of common skin disease, the chronic easily recurrence of the course of disease, may have a strong impact on the study of patient, work,
Motion, interpersonal relationships and social activities, decline the quality of life of patient, have serious shadow to teen-age psychology and society
Ring, therefore acne is also a kind of psychosomatic that can not be ignored, according to epidemiology statistics, its incidence of disease is 80-90%.It is clinical
Show as being apt to occur in face, forehead, next to that chest, back and shoulder, mostly symmetrical, be often accompanied by the mound of seborrhea
Rash, tubercle, warts, tumour etc..Clinically contributed to correctly to select therapeutic scheme according to acne the skin being grievously injured grading, at present
It is classified according to international improved method, is divided into acne according to acne skin lesion property and the order of severity：Slightly (I levels)：With acne
Based on, a small amount of papule, warts, total skin lesion are less than 30；Moderate (II levels)：There are acne, the papule and warts of moderate quatity, total skin
Damage is at 31-50；Moderate (III grade)：A large amount of papules and warts, accidental big inflammatory skin lesion, widely distributed, total skin lesion number exists
Between 51-100, tubercle is less than 3；Severe (IV grade)：Nodositas, Cystic and/or property acne, with pain and form capsule
Swollen, total skin lesion is more than 100, and tubercle or tumour are more than 3.For acne because more complicated, doctor trained in Western medicine thinks its morbidity mainly and property
The factors such as hormonal readiness, sebaceous glands are largely secreted, propionibacterium acnes propagation, the dyskeratosis of pilosebaceous duct and inflammation
It is relevant.
According to its Forming Mechanism, western medical treatment acne is mainly started with from the following aspect：
1. suppress acne Propionibacterium；
2. control inflammation；
3. suppress dyskeratosis；
4. suppress sebum secretion.
Treatment acne common recognition in the world can reach following common recognition for acne：Light moderate acne more options topical Retinoids class, resist
Microbiology class and other there is anti-inflammatory activity, can diminish inflammation medicine.For serious acne, trunk is particularly occurred in
The acne of position and patient that is not good enough to external curing and having cicatrization excessive risk then need systematic treating.
Current traditional common drug, which has, orally ties up the medicines such as sour A classes, antibiotic, contraceptive, antiandrogen, but because of above-mentioned medicine
The problem of resistance and drug side-effect be present in thing.Therefore, some patientss tend to select safe and effective outer treating method treatment seat
Sore.The physical treatment of rising in recent years such as light power, infrared laser, broad spectrum light source, pulsed dye laser, intense pulsed light, potassium
Phosphate laser etc. by the emperor himself, it can improve the inflammatory skin lesion of acne in a short time, but these external application physiotherapy apparatus would generally
Pain, erythema, swelling and pigmentation be present and increase etc. bad anti-, and its is costly, it is not easy to received by patient,
It is unfavorable for the popularization for the treatment of.
Although also there is the Chinese medicine preparation for developing treatment acne the country in the prior art, it is generally only oral preparations, such as
Application No. CN201010230053.4 patent " Chinese medicine composition for the treatment of acne ", even occurs head for some patients
Cross effect.
The content of the invention
It is an object of the invention to provide one kind carry it is easy to use, have significant curative effect to acne, Small side effects, economical and practical
Easy to spread Chinese medicine composition for acne, the facial mask prepared and its preparation and application.
The present invention is achieved by the following technical solution：
A kind of Chinese medicine composition for acne includes following component：It is the Radix Astragali, radix scutellariae, rheum officinale, the bighead atractylodes rhizome, the root of Dahurain angelica, the bletilla striata, white
Common vetch, radix ampelopsis, PORIA ALBA, oldenlandia diffusa, the red sage root.
Further, the Chinese medicine composition for acne includes following parts by weight of component：1-2 parts Radix Astragali, 1-2 parts radix scutellariae,
1-2 parts rheum officinale, 1-2 parts bighead atractylodes rhizome, 1-2 parts root of Dahurain angelica, 1-2 parts bletilla striata, 1-2 parts radix cynanchi atrati, 1-2 parts radix ampelopsis, 1-2 parts PORIA ALBA, 1-2 parts
Oldenlandia diffusa, 1-2 part reds sage root.
It is further preferred that the Chinese medicine composition for acne includes following parts by weight of component：1.5 parts of Radixs Astragali, 1.5 parts of Huangs
A kind of reed mentioned in ancient books, 1.5 parts of rheum officinales, 1.5 parts of bighead atractylodes rhizomes, 1.5 parts of roots of Dahurain angelica, 1.5 portions of bletilla striatas, 1.5 portions of radix cynanchi atratis, 1.5 portions of radix ampelopsis, 1.5 parts of PORIA ALBAs,
1.5 parts of oldenlandia diffusas, 1.5 parts of reds sage root.
Further, in the above-mentioned Chinese medicine composition for acne, each group was divided into the powder of 300 mesh sieves.
The present invention also provides a kind of facial mask, is prepared by the Chinese medicine composition for being used for acne as described above, including such as the following group
Point：The Radix Astragali, radix scutellariae, rheum officinale, the bighead atractylodes rhizome, the root of Dahurain angelica, the bletilla striata, radix cynanchi atrati, radix ampelopsis, PORIA ALBA, oldenlandia diffusa, the red sage root and water.
Further, the mass ratio of traditional Chinese medicinal components and water described in above-mentioned facial mask is 1：(1-1.1).The water is preferably to steam
Distilled water.
The present invention also provides a kind of preparation method of the above-mentioned facial mask for acne, including step：Each component is mixed, added
Enter water, stir into uniform pasty state and produce face mask of traditional Chinese medicine.
The application method of the face mask of traditional Chinese medicine of gained, including step are prepared according to above-mentioned preparation method：Face mask of traditional Chinese medicine is coated
Gone behind affected part, 20-40min with 20-40 DEG C of washing.
Further, in the application method of above-mentioned face mask of traditional Chinese medicine, thickness of the face mask of traditional Chinese medicine coated on affected part is 2-
3mm。
Further, in the application method of above-mentioned face mask of traditional Chinese medicine, face mask of traditional Chinese medicine coating 1 time daily, continuous coating is extremely
It is few 4 weeks.
The facial mask of Chinese medicine composition and its preparation provided by the present invention for acne, Inspiration Sources are in currently a popular life
Facial mask living, popular acceptance is high, and patient compliance is good.We are related to the preparation of traditional Chinese herbal decoction during Clinical practice, are facing
Curative effect is obvious during bed use, but convenience is poor, is unfavorable for carrying, because the current Clinical practice of face mask of traditional Chinese medicine is extensive, therefore will
Facial mask is made in we can resolving carbuncle and expulsing boil, expelling pus and promoting granulation, moreover it is possible to reaches reduction recurrence, the facial mask of cosmetic result.Present invention treatment
The mechanism of acne is to absorb drug percutaneous skin by the transdermal drug delivery system of skin surface, can avoid first pass effect, make medicine
Thing persistent and adverse reaction is slight, be advantageous to Chinese medicine various composition and play curative effect.
At present, this research through look into it is new there is no relevant report, the present invention for treat acne provide it is simple and easy to do, economic, practical,
New method easy to spread.
Embodiment
With reference to specific embodiment, the present invention will be further described.The embodiment is only being preferable to carry out for the present invention
Example, is not intended to limit the invention, for those skilled in the art, the present invention can have various changes and change
Change.Within the spirit and principles of the invention, any modification, equivalent substitution and improvements made etc., should be included in the present invention
Protection domain within.
Embodiment 1
The following medicinal powder for crossing 300 mesh sieves are mixed into obtain powder in clean vessel：The 15kg Radixs Astragali, 15kg radix scutellariaes, 15kg are big
Huang, the 15kg bighead atractylodes rhizomes, the 15kg roots of Dahurain angelica, the 15kg bletilla striatas, 15kg radix cynanchi atratis, 15kg radix ampelopsis, 15kg PORIA ALBAs, 15kg oldenlandia diffusas,
The 15kg reds sage root.In use, facial mask is prepared as follows：By gained powder and distilled water according to 1:1.05 mass ratio mixing
Stir into uniform pasty state and produce face mask of traditional Chinese medicine.
Face mask of traditional Chinese medicine is applied to homeliness type acne patient facial region, facial mask thickness is 2-3mm, is paid attention to avoiding around eyes, nose
Hole and lip.Facial mask is washed away with 35 DEG C of warm water after 30min, daily facial mask surface application 1 time, continuous treatment 4 weeks, use face mask of traditional Chinese medicine
Period disables the medicine and cosmetics of other treatment homeliness type acne.
Embodiment 2
The following medicinal powder for crossing 300 mesh sieves are mixed into obtain powder in clean vessel：The 10kg Radixs Astragali, 15kg radix scutellariaes, 20kg are big
Huang, the 15kg bighead atractylodes rhizomes, the 15kg roots of Dahurain angelica, the 20kg bletilla striatas, 15kg radix cynanchi atratis, 10kg radix ampelopsis, 15kg PORIA ALBAs, 15kg oldenlandia diffusas,
The 20kg reds sage root.In use, facial mask is prepared as follows：By gained powder and distilled water according to 1:1.1 mass ratio mixing
Stir into uniform pasty state and produce face mask of traditional Chinese medicine.
Face mask of traditional Chinese medicine is applied to homeliness type acne patient facial region, facial mask thickness is 2-3mm, is paid attention to avoiding around eyes, nose
Hole and lip.Facial mask is washed away with 30 DEG C of warm water after 40min, daily facial mask surface application 1 time, continuous treatment 4 weeks, use face mask of traditional Chinese medicine
Period disables the medicine and cosmetics of other treatment homeliness type acne.
Embodiment 3
The following medicinal powder for crossing 300 mesh sieves are mixed into obtain powder in clean vessel：The 20kg Radixs Astragali, 10kg radix scutellariaes, 15kg are big
Huang, the 15kg bighead atractylodes rhizomes, the 105kg roots of Dahurain angelica, the 20kg bletilla striatas, 15kg radix cynanchi atratis, 20kg radix ampelopsis, 10kg PORIA ALBAs, 15kg oldenlandia diffusas,
The 10kg reds sage root.In use, facial mask is prepared as follows：By gained powder and distilled water according to 1:1 mass ratio mixing is stirred
Mix uniform pasty state and produce face mask of traditional Chinese medicine.
Face mask of traditional Chinese medicine is applied to homeliness type acne patient facial region, facial mask thickness is 2-3mm, is paid attention to avoiding around eyes, nose
Hole and lip.Facial mask is washed away with 40 DEG C of warm water after 40min, daily facial mask surface application 1 time, continuous treatment 4 weeks, use face mask of traditional Chinese medicine
Period disables the medicine and cosmetics of other treatment homeliness type acne.
Comparative example 1
With reference to the relevant report of face mask of traditional Chinese medicine treatment acne, with reference to modern pharmacological research, and previous tretament experience is combined, examined
It is 85 to consider sample size needed for patient, and it is 15% to estimate rate lost to follow-up, therefore two groups need to respectively include 200.This research needs sample size altogether
It is at least 200.
Sample content and packet count 2 are inputted into PEMS3.1 statistical packages, output is randomly assigned result and prepares random card,
Load light tight envelope and the serialization number on envelope, it is suitable by the case for meeting inclusive criteria to enter clinical priority during clinical implementation
Sequence number on sequence associated envelope, card taking is sealed off, GP TH is carried out by the random card in envelope.By seminar send special messenger keeping and
Random envelope is provided, and enters a group order in strict accordance with patient and is corresponding in turn to numbering granting envelope.
Research method：Patients with acne 200, product of the embodiment of the present invention are treated 100, kecuocryptone group 100, carried out
Safety indexes record, adverse reaction record.
Case selection standard meets《Clinical dermatology》Homeliness type acne examines new standard.Syndrome Scale quantifies with reference to 2002
New Chinese medicine guideline of clinical investigations：
(1) skin rash typus：1 slight (I levels)：Based on acne, a small amount of papule, warts, moderate (II levels)：There are acne, in
Etc. the papule and warts of quantity, moderate (III grade)：A large amount of papules and warts, accidental big inflammatory skin lesion, widely distributed, severe
(IV grade)：Nodositas, Cystic and/or property acne, with pain and form tumour
(2) fash quantity：1 slight (I levels)：Total skin lesion is less than 30；Moderate (II levels)：Total skin lesion is at 31-50；Moderate
(III grade)：For total skin lesion number between 51-100, tubercle is less than 3；Severe (IV grade)：Total skin lesion is more than 100, tubercle or capsule
It is swollen to be more than 3.
Patient selects：All one for meeting above-mentioned tcm diagnosis standard primary symptom (1) and secondary disease；Person between age 13-45 year；
The patient of any cosmetics and other treatment acne medicine was not used in 2 weeks；In the case where Ethics Committee is approved, ensure patient
Under maximum benefit, it is ready to receive this project person, and sign informed consent form.
Hereinafter exclusion standard is chosen for patient：Gestation and women breast-feeding their children；Merge malignant tumour, connective tissue disease person；
To this medicine allergy or to drug ingedient allergy sufferers；It is associated with cardio cerebrovascular affection, diabetes, internal system, haematological systemic disorder
Change and mental illness；Extraordinary type person；Drug-induced acne, occupational acne；Other cases of inclusive criteria are not met.
The metamorphosis that Dermatology Outpatient Department and inpatient department accept for medical treatment during case chooses certain hospital in October, -2017 in November, 2016 is anti-
Dermatoses rheumatism heat type patient is answered, meets above-mentioned diagnosis, inclusive criteria.
This project intends taking the research method of random (random digits table) control, MethodsThe cases enrolled 200, is randomly divided into two
Group.
Control group：It is classified as wiping treatment outside the simple external application kecuocryptone gel of I, II patient for acne, Consult drug is said
It is bright, once in the morning and once at night, face is cleaned with warm water, then kecuocryptone gel is applied to affected part.III, IV trouble is classified as acne
Person gives oral traditional Chinese medicine treatment simultaneously according to traditional Chinese medical science diagnosis and treatment standard differentiation of symptoms and signs for classification of syndrome, gives and wipes treatment outside external application kecuocryptone gel.
Treatment method is the same.
Experimental group：The white Sanhuang San facial mask external application for curing of the simple external application stilbene of I, II patient is classified as acne, for acne
It is classified as III, IV patient and gives oral traditional Chinese medicine treatment simultaneously according to traditional Chinese medical science diagnosis and treatment standard differentiation of symptoms and signs for classification of syndrome, gives external application stilbene Bai Sanhuang
Dissipate facial mask external application for curing.
Observation index：
(1) related symptoms and sign situation of change, such as skin rash typus, fash quantity.
(2) dermatology life quality index.(being shown in Table 3)
(3) stool and urine, tongue picture, pulse condition.
(4) safety indexes：Vital sign：Blood pressure, body temperature, breathing, pulse, heart rate, the rhythm of the heart.Blood, urine, feces routinize
Test, electrocardiogram, liver function (ALT, AST), renal function (BUN, Cr), blood glucose (FPG) check.
Above index, respectively detected once before experiment and after off-test.
The adverse reaction being likely to occur, answer detailed observational record its clinical manifestation, the order of severity, Testing index is abnormal, disappears
Except method and time etc..According in symptom, sign scalar quantization index without, it is light, in, weight degree remembers with 0,1,2,3 point respectively.
Curative effect determinate standard with reference to 2002 new Chinese medicine guideline of clinical investigations, tcm syndrome curative effect determinate standard according to
Integration method judges tcm syndrome curative effect.Calculated by Nimodipine method, curative effect of disease criterion is used as using skin lesion extinction rate.
Fash overall score before skin lesion extinction rate=(fash overall score after fash overall score-treatment before treatment)/treatment.
Recovery from illness：Deflorescence rate >=95%.
It is effective：95% ＞ deflorescence rate >=70%, or disease severity reduce by more than 2 degree.
Take a turn for the better：70% ＞ deflorescence rate >=30%, or disease severity reduce by more than 1 degree.
It is invalid：Deflorescence rate ＜ 30%, or fash it is counter see increase.
Calculated using Nimodipine method, the total reduced rate to be scored using fash plus other symptoms is used as tcm syndrome efficacy determination
Standard：
Recovery from illness：Overall score rate reduces >=95%；
It is effective：95% ＞ overall scores rate reduces >=70%；
Take a turn for the better：70% ＞ overall scores rate reduces >=30%；
It is invalid：Overall score rate reduces ＜ 30%.
Experimental group, control group total effective rate 69.57%, cure rate 21.0% are used as using embodiment 1；Experimental group is always effective
Rate 84.56%, cure rate 31.33%.
Claims (10)
1. a kind of Chinese medicine composition for acne, it is characterised in that including following component：
The Radix Astragali, radix scutellariae, rheum officinale, the bighead atractylodes rhizome, the root of Dahurain angelica, the bletilla striata, radix cynanchi atrati, radix ampelopsis, PORIA ALBA, oldenlandia diffusa, the red sage root.
2. the Chinese medicine composition according to claim 1 for acne, it is characterised in that including following parts by weight of component：
1-2 parts Radix Astragali, 1-2 parts radix scutellariae, 1-2 parts rheum officinale, 1-2 parts bighead atractylodes rhizome, 1-2 parts root of Dahurain angelica, 1-2 parts bletilla striata, 1-2 parts radix cynanchi atrati, 1-2
Part radix ampelopsis, 1-2 parts PORIA ALBA, 1-2 parts oldenlandia diffusa, 1-2 part reds sage root.
3. the Chinese medicine composition according to claim 1 for acne, it is characterised in that including following parts by weight of component：
1.5 parts of Radixs Astragali, 1.5 parts of radix scutellariaes, 1.5 parts of rheum officinales, 1.5 parts of bighead atractylodes rhizomes, 1.5 parts of roots of Dahurain angelica, 1.5 portions of bletilla striatas, 1.5 parts of radix cynanchi atratis, 1.5
Part radix ampelopsis, 1.5 parts of PORIA ALBAs, 1.5 parts of oldenlandia diffusas, 1.5 parts of reds sage root.
4. the Chinese medicine composition as claimed in any of claims 1 to 3 for acne, it is characterised in that
The each group was divided into the powder of 300 mesh sieves.
5. facial mask prepared by the Chinese medicine composition for acne as described in any one in Claims 1-4, its feature exist
In, including following component：
The Radix Astragali, radix scutellariae, rheum officinale, the bighead atractylodes rhizome, the root of Dahurain angelica, the bletilla striata, radix cynanchi atrati, radix ampelopsis, PORIA ALBA, oldenlandia diffusa, the red sage root and water.
6. facial mask according to claim 5, it is characterised in that
The mass ratio of the traditional Chinese medicinal components and water is 1：(1-1.1).
7. the preparation method of the facial mask as described in claim 5 or 6, it is characterised in that including step：
Each component is mixed, water is added, stirs into uniform pasty state and produce face mask of traditional Chinese medicine.
8. preparation method as claimed in claim 7 prepares the application method of the face mask of traditional Chinese medicine of gained, it is characterised in that including step
Suddenly：
Face mask of traditional Chinese medicine is coated on affected part, gone after 20-40min with 20-40 DEG C of washing.
9. application method according to claim 6, it is characterised in that
Thickness of the face mask of traditional Chinese medicine coated on affected part is 2-3mm.
10. application method according to claim 6, it is characterised in that
Face mask of traditional Chinese medicine coating 1 time daily, continuous coating at least 4 weeks.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711007213.7A CN107714941A (en) | 2017-10-25 | 2017-10-25 | A kind of Chinese medicine composition for acne, the facial mask prepared and its preparation and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711007213.7A CN107714941A (en) | 2017-10-25 | 2017-10-25 | A kind of Chinese medicine composition for acne, the facial mask prepared and its preparation and application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107714941A true CN107714941A (en) | 2018-02-23 |
Family
ID=61212729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711007213.7A Pending CN107714941A (en) | 2017-10-25 | 2017-10-25 | A kind of Chinese medicine composition for acne, the facial mask prepared and its preparation and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107714941A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103432244A (en) * | 2013-09-11 | 2013-12-11 | 余红波 | Composition having acne removing function |
| CN107158294A (en) * | 2017-06-09 | 2017-09-15 | 芦荣朋 | A kind of Chinese medicine composition for repairing skin of face and its preparation method and application |
-
2017
- 2017-10-25 CN CN201711007213.7A patent/CN107714941A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103432244A (en) * | 2013-09-11 | 2013-12-11 | 余红波 | Composition having acne removing function |
| CN107158294A (en) * | 2017-06-09 | 2017-09-15 | 芦荣朋 | A kind of Chinese medicine composition for repairing skin of face and its preparation method and application |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102284051A (en) | Medicine for treating chloasma | |
| CN106728457A (en) | A kind of Traditional Chinese medicine acne treatment mask | |
| Zhi et al. | Treatment of pulmonary fibrosis in one convalescent patient with corona virus disease 2019 by oral traditional Chinese medicine decoction: A case report | |
| CN109568477A (en) | A kind of pharmaceutical composition and its preparation method and application for treating thyroid nodule | |
| CN107714941A (en) | A kind of Chinese medicine composition for acne, the facial mask prepared and its preparation and application | |
| CN104784667A (en) | Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method thereof | |
| CN109865028A (en) | A kind of Chinese medicinal ointment and preparation method thereof for the treatment of acne easy to carry, easy-to-use | |
| CN101596302A (en) | A kind of treatment treating coronary heart disease and angina pectoris and preparation method thereof | |
| CN100584367C (en) | Medicine composition for treating fracture and its preparation method | |
| CN103127415B (en) | Traditional Chinese medicine for treating post-stroke limb numbness | |
| CN109865017A (en) | A kind of paste and preparation method thereof of easy-to-use treatment acne | |
| Zhao et al. | Efficacy and Safety of Tongning Gel for Knee Osteoarthritis: A Multicentre, Randomized, Double‐Blinded, Parallel, Placebo‐Controlled, Clinical Trial | |
| CN104547634B (en) | A kind of purposes of Chinese medicine composition in treatment bedsore medicine is prepared | |
| CN104043008A (en) | External traditional Chinese medicinal composition for treating myofascitis and preparation method thereof | |
| CN102266486A (en) | Medicament for desensitizing, eliminating rashes and removing sores | |
| CN104117018A (en) | Traditional Chinese medicine composition for treating coronary heart disease | |
| CN1351887A (en) | Externally applied Chinese medicine decoction | |
| CN104587128B (en) | A kind of medical composition and its use treated first and subtracted | |
| CN103316161B (en) | Acne cream and preparing process thereof | |
| CN112057555B (en) | A composition for treating keratotic skin diseases and its preparation method | |
| CN100594914C (en) | Medicine for curing coronary heart disease | |
| CN105663868A (en) | Traditional Chinese medicinal composition for treating aplastic anemia | |
| CN105748391A (en) | Multi-effect beauty mask and preparation method thereof | |
| CN102423396B (en) | Composition used for treating rheumatoid arthritis | |
| CN102210822B (en) | Traditional Chinese medicine for treating rickets |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180223 |