CN107693570A - The concocting method of the river Radix Astragali - Google Patents

The concocting method of the river Radix Astragali Download PDF

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Publication number
CN107693570A
CN107693570A CN201711123751.2A CN201711123751A CN107693570A CN 107693570 A CN107693570 A CN 107693570A CN 201711123751 A CN201711123751 A CN 201711123751A CN 107693570 A CN107693570 A CN 107693570A
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China
Prior art keywords
radix astragali
river
river radix
rice
concocting method
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CN201711123751.2A
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Chinese (zh)
Inventor
吴可
朱文强
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Navy Blue Xiangcheng Pharmaceutical Co Ltd
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Navy Blue Xiangcheng Pharmaceutical Co Ltd
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Priority to CN201711123751.2A priority Critical patent/CN107693570A/en
Publication of CN107693570A publication Critical patent/CN107693570A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses a kind of concocting method of the river Radix Astragali, comprise the following steps:The river Radix Astragali is cleaned, run through, is cut into slices, is dried;By, with the same stir-fry of the river Radix Astragali, cooling, sieving removing is windproof to obtain river astragalus mongholicus tablet after windproof crushing;It is broken that ground rice, addition distilled water and fructus schisandrae filter to obtain ripe Rice & peanut milk with boiling that ground rice will be obstructed;Ripe Rice & peanut milk and river astragalus mongholicus tablet are mixed thoroughly, dries, obtains the metric system river Radix Astragali.The effect of concocting method of the present invention can dramatically increase the river Radix Astragali, has good application value.

Description

The concocting method of the river Radix Astragali
Technical field
The invention belongs to the preprocessing technical field of Chinese medicine, more particularly to the concocting method of the river Radix Astragali.
Background technology
River Huang cyclopentadienyl is the legume shuttle fruit Radix Astragali, spends more the dry root of the Radix Astragali and astragalus chrysopterus Bunge, has invigorating qi for strengthening superficies, diuresis Eliminating toxic, apocenosis, the effect of expelling pus and promoting granulation, in Sichuan province frequently as pharmacopeia Radix Astragali substitute application.It has invigorating qi for strengthening superficies, profit Urinate eliminating toxic, apocenosis, the effect of expelling pus and promoting granulation.Clinic is usually used in treatment deficiency of vital energy weak, and deficiency of food is just quiet, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, has blood in stool Uterine bleeding, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, deficiency of blood paralysis is yellow, Heat Diabetes, chronic rephrilis protinuria, sugar Urine disease.The chemical composition that Chinese medicine contains is that it plays the material base of unique drug effect, but the complicated component of Chinese medicine, different processings Method can make its active ingredient change, thus understand its property of medicine and being changed to for chemical composition occur with the difference of processing Close important.On Chinese history the concocting method of the Radix Astragali have cutting, steam, honey is processed, honey steams, honey is fried, salt roasting, salt steam, wine steam, Wine is fried, wine boils, stir frying with ginger juice, human milk system, rice swill etc., at present main method be honey process, salt system and wine system.
The content of the invention
The invention discloses a kind of concocting method of the river Radix Astragali, comprise the following steps:
The river Radix Astragali is cleaned, run through, is cut into slices, is dried;It will remove anti-with stir-fry, cooling, sieving with the river Radix Astragali after windproof crushing Wind obtains river astragalus mongholicus tablet;
It is broken that ground rice, addition distilled water and fructus schisandrae filter to obtain ripe Rice & peanut milk with boiling that ground rice will be obstructed;
Ripe Rice & peanut milk and river astragalus mongholicus tablet are mixed thoroughly, dries, obtains the metric system river Radix Astragali.
Preferably, the river Radix Astragali is 1 with windproof mass ratio:1-5.
Preferably, the mass ratio of the river Radix Astragali and polished rice is 5-10:1.
Preferably, the river Radix Astragali obtains mass ratio with fructus schisandrae is:10-20:1.
Preferably, the mass ratio of ground rice and distilled water is 1:3-6.
Embodiment
Embodiment 1
River Radix Astragali 10kg is cleaned, run through, is cut into slices, is dried, with the river Radix Astragali with stir-fry 10 minutes, mistake after windproof 20kg is crushed Screen out windproof powder and obtain river astragalus mongholicus tablet.Mixed after polished rice 2kg is crushed with fructus schisandrae 1kg, add 10kg distilled water, boil 10 minutes, filter to obtain ripe Rice & peanut milk.Ripe Rice & peanut milk and river astragalus mongholicus tablet are mixed thoroughly, dry the metric system river Radix Astragali.
Embodiment 2
River Radix Astragali 10kg is cleaned, run through, is cut into slices, is dried, with the river Radix Astragali with stir-fry 15 minutes, mistake after windproof 40kg is crushed Screen out windproof powder and obtain river astragalus mongholicus tablet.Mixed after polished rice 1kg is crushed with fructus schisandrae 0.5kg, add 5kg distilled water, boil Boiling 15 minutes, filters to obtain ripe Rice & peanut milk.Ripe Rice & peanut milk and river astragalus mongholicus tablet are mixed thoroughly, dry the metric system river Radix Astragali.
Embodiment 3
River Radix Astragali 10kg is cleaned, run through, is cut into slices, dries, obtains river astragalus mongholicus tablet.By polished rice 2kg crush after with fructus schisandrae 1kg is mixed, and is added 10kg distilled water, is boiled 10 minutes, filter to obtain ripe Rice & peanut milk.Ripe Rice & peanut milk and river astragalus mongholicus tablet are mixed thoroughly, dry The metric system river Radix Astragali.
Embodiment 4
River Radix Astragali 10kg is cleaned, run through, is cut into slices, is dried, with the river Radix Astragali with stir-fry 10 minutes, mistake after windproof 20kg is crushed Screen out windproof powder and obtain river astragalus mongholicus tablet.After polished rice 2kg is crushed, 10kg distilled water is added, boils 10 minutes, filters to obtain ripe rice Slurry.Ripe Rice & peanut milk and river astragalus mongholicus tablet are mixed thoroughly, dry the metric system river Radix Astragali.
Embodiment 5
River Radix Astragali 10kg is cleaned, run through, is cut into slices, is dried, with the river Radix Astragali with stir-fry 10 minutes, mistake after windproof 20kg is crushed Screen out windproof powder and obtain river astragalus mongholicus tablet.After polished rice 2kg is crushed, 10kg distilled water is added, stirring, filters to obtain Rice & peanut milk.By rice Slurry is mixed thoroughly with river astragalus mongholicus tablet, dry the metric system river Radix Astragali.
The research of the Radix Astragali, resist oxygen lack and antifatigue effect
Experimental animal group technology:Packet takes 60 mouse, is randomly divided into 3 groups:Control group and the large and small dosage group of the Radix Astragali. Large and small dosage group is administered (embodiment 1-5, and do not process the Radix Astragali) respectively, and dosage presses 0.6g/kg, and 0.2g/kg is filled daily Stomach 1 time, continuous 7d, control group is with isometric physiological saline gavage.
Resist oxygen lack is tested:This item tests every group of 20 mouse, and after last gavage 24h, mouse is filled into sodium stone by only putting into In wide-mouth bottle closed grey 20g 250ml, every mouse survival time is recorded.
Antifatigue experiment:Every group of 20 mouse, after last gavage 24h, each group mouse is respectively in 37 DEG C of deep 40cm trips of temperature Swimming pool went swimming, after 45min, mouse is taken out, eyeball is plucked and takes blood, pass through the content that colorimetric analysis determines hepatic glycogen.
Result of the test:
1. hypoxia endurance test:
Compared with control group, the heavy dose of Astragalus Root P.E of Examples 1 and 2 can be obviously prolonged mouse under anaerobic Time-to-live (P<0.05), but low dose of there was no significant difference.Compared with control group:The large and small dosage in embodiment 3,4 and 5 Astragalus Root P.E fail to be obviously prolonged the time-to-live (P of mouse under anaerobic>0.05) Milkvetch Root, not processed Large and small dosage extract also fails to be obviously prolonged the time-to-live (P of mouse under anaerobic>0.05).
Table 1;Hypoxia endurance test result
* representing relatively there is significant difference with blank control group, i.e. P is less than 0.05,
2. anti-fatigue test result;
Compared with control group, the content of hepatic glycogen substantially increases (P after the large and small dosage group mouse swimming of Examples 1 and 2< 0.05), difference has statistical significance.Compared with control group:The Astragalus Root P.E group of the large and small dosage of embodiment 3,4 and 5 The content of hepatic glycogen does not have obvious increase (P after mouse swimming>0.05) the large and small dosage extraction for the Milkvetch Root, not processed The content of hepatic glycogen does not have obvious increase (P yet after the mouse swimming of thing group>0.05).
The anti-fatigue test result of table 2
Group Dosage (g/kg) Hepatic glycogen C/mgkg-1
Blank group Physiological saline 23.5±4.2
Embodiment 1 0.6 49.8±8.1*
0.2 31.5±6.3*
Embodiment 2 0.6 42.7±4.2*
0.2 33.5±3.8*
Embodiment 3 0.6 26.8±7.1
0.2 24.6±4.2
Embodiment 4 0.6 25.6±2.5
0.2 24.8±3.9
Embodiment 5 0.6 26.6±6.3
0.2 25.4±3.2
Powder is not processed 0.6 24.4±4.1
0.2 23.8±3.5
Finally illustrate, the above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, although with reference to compared with The present invention is described in detail good embodiment, it will be understood by those within the art that, can be to the skill of the present invention Art scheme is modified or equivalent substitution, and without departing from the objective and scope of technical solution of the present invention, it all should cover at this Among the right of invention.

Claims (5)

1. a kind of concocting method of the river Radix Astragali, it is characterised in that comprise the following steps:
The river Radix Astragali is cleaned, run through, is cut into slices, is dried;After windproof crushing windproof obtain will be removed with the same stir-fry of the river Radix Astragali, cooling, sieving River astragalus mongholicus tablet;
It is broken that ground rice, addition distilled water and fructus schisandrae filter to obtain ripe Rice & peanut milk with boiling that ground rice will be obstructed;
Ripe Rice & peanut milk and river astragalus mongholicus tablet are mixed thoroughly, dries, obtains the metric system river Radix Astragali.
2. the concocting method of the river Radix Astragali as claimed in claim 1, it is characterised in that the river Radix Astragali is 1 with windproof mass ratio: 1-5。
3. the concocting method of the river Radix Astragali as claimed in claim 1, it is characterised in that the mass ratio of the river Radix Astragali and polished rice is 5-10: 1。
4. the concocting method of the river Radix Astragali as claimed in claim 1, it is characterised in that the river Radix Astragali obtains mass ratio with fructus schisandrae and is: 10-20:1.
5. the concocting method of the river Radix Astragali as claimed in claim 1, it is characterised in that the mass ratio of ground rice and distilled water is 1:3-6.
CN201711123751.2A 2017-11-14 2017-11-14 The concocting method of the river Radix Astragali Pending CN107693570A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711123751.2A CN107693570A (en) 2017-11-14 2017-11-14 The concocting method of the river Radix Astragali

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711123751.2A CN107693570A (en) 2017-11-14 2017-11-14 The concocting method of the river Radix Astragali

Publications (1)

Publication Number Publication Date
CN107693570A true CN107693570A (en) 2018-02-16

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Application Number Title Priority Date Filing Date
CN201711123751.2A Pending CN107693570A (en) 2017-11-14 2017-11-14 The concocting method of the river Radix Astragali

Country Status (1)

Country Link
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Application publication date: 20180216