CN107686513A - 免疫球蛋白G Fc区结合多肽 - Google Patents

免疫球蛋白G Fc区结合多肽 Download PDF

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Publication number
CN107686513A
CN107686513A CN201710866126.0A CN201710866126A CN107686513A CN 107686513 A CN107686513 A CN 107686513A CN 201710866126 A CN201710866126 A CN 201710866126A CN 107686513 A CN107686513 A CN 107686513A
Authority
CN
China
Prior art keywords
igg
polypeptide
binding
amino acid
binding polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710866126.0A
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English (en)
Chinese (zh)
Inventor
L.阿布拉姆森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
Original Assignee
GE Healthcare Bio Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Bio Sciences Corp filed Critical GE Healthcare Bio Sciences Corp
Publication of CN107686513A publication Critical patent/CN107686513A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28033—Membrane, sheet, cloth, pad, lamellar or mat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/282—Porous sorbents
    • B01J20/285—Porous sorbents based on polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B01J20/3274—Proteins, nucleic acids, polysaccharides, antibodies or antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
CN201710866126.0A 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽 Pending CN107686513A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10155835.1 2010-03-08
EP10155835 2010-03-08
CN2011800128442A CN102811782A (zh) 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2011800128442A Division CN102811782A (zh) 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽

Publications (1)

Publication Number Publication Date
CN107686513A true CN107686513A (zh) 2018-02-13

Family

ID=43927858

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201710866126.0A Pending CN107686513A (zh) 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽
CN2011800128442A Pending CN102811782A (zh) 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2011800128442A Pending CN102811782A (zh) 2010-03-08 2011-03-07 免疫球蛋白G Fc区结合多肽

Country Status (8)

Country Link
US (1) US9175067B2 (https=)
EP (2) EP2977088B1 (https=)
JP (1) JP5951509B2 (https=)
CN (2) CN107686513A (https=)
CA (1) CA2789738C (https=)
DK (2) DK2544785T3 (https=)
ES (1) ES2641896T3 (https=)
WO (1) WO2011110515A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120165650A1 (en) 2010-12-22 2012-06-28 General Electric Company Her2 binders
KR102399024B1 (ko) * 2014-06-13 2022-05-17 애피바디 에이비 신규 폴리펩티드
US10633423B2 (en) 2014-06-13 2020-04-28 Affibody Ab IL-6-binding polypeptide complex
EP3245224B1 (en) * 2015-01-12 2020-07-15 Affibody AB Il-17a-binding polypeptides
EP3356829A4 (en) * 2015-10-02 2019-02-27 The Macfarlane Burnet Institute For Medical Research And Public Health Ltd BINDING TESTS AND METHOD FOR PROBING ANTIBODY FUNCTION WITH FC BINDING MULTIMES
JP6818305B2 (ja) * 2016-09-01 2021-01-20 国立研究開発法人産業技術総合研究所 非天然型立体構造を形成した抗体に親和性を示すポリペプチド
UY37651A (es) 2017-03-31 2018-10-31 Swedish Orphan Biovitrum Ab Publ Polipéptido de unión al il-1r-i
GB201717446D0 (en) 2017-10-24 2017-12-06 Evox Therapeutics Ltd Affinity purification of engineering extracellular vesicles
CN111315887B (zh) * 2017-11-09 2024-02-06 东曹株式会社 免疫球蛋白结合性蛋白质
CN112969708B (zh) * 2018-11-12 2024-07-05 纳维格蛋白质有限公司 缺乏免疫球蛋白fc结构域结合亲和力的新三螺旋多肽及其用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143844A (en) * 1985-12-13 1992-09-01 Kabigen Ab Construction of an igg binding protein to facilitate downstream processing using protein engineering
CN1723219B (zh) * 2003-11-13 2010-05-26 韩美药品工业株式会社 利用免疫球蛋白片段的蛋白质复合物及其制备方法
CN101952302A (zh) * 2007-12-21 2011-01-19 阿菲博迪公司 具有her2亲和性的新多肽

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7709209B2 (en) * 2002-03-25 2010-05-04 Ge Healthcare Bio-Sciences Ab Protein ligands
US20050147962A1 (en) * 2002-11-19 2005-07-07 Wagstrom Christopher R. Display of dimeric proteins on phage
EP2190863B1 (en) * 2007-07-31 2015-09-02 Affibody AB New albumin binding compositions, methods and uses
EP2077272A1 (en) * 2007-12-21 2009-07-08 Affibody AB Polypeptide libraries with a predetermined scaffold
US9238810B2 (en) 2008-06-05 2016-01-19 Affibody Ab Polypeptide

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143844A (en) * 1985-12-13 1992-09-01 Kabigen Ab Construction of an igg binding protein to facilitate downstream processing using protein engineering
CN1723219B (zh) * 2003-11-13 2010-05-26 韩美药品工业株式会社 利用免疫球蛋白片段的蛋白质复合物及其制备方法
CN101952302A (zh) * 2007-12-21 2011-01-19 阿菲博迪公司 具有her2亲和性的新多肽

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SULICA A 等: "Effect of protein A of Staphylococcus aureus on the binding of monomeric and polymeric IgG to Fc receptor-bearing cells", 《IMMUNOLOGY》 *
逄少堃 等: "葡萄球菌蛋白A活性机制与现代应用", 《生命的化学》 *

Also Published As

Publication number Publication date
WO2011110515A1 (en) 2011-09-15
DK2544785T3 (en) 2016-01-18
JP5951509B2 (ja) 2016-07-13
CA2789738A1 (en) 2011-09-15
US9175067B2 (en) 2015-11-03
EP2977088B1 (en) 2017-08-02
EP2544785B1 (en) 2015-09-30
DK2977088T3 (en) 2017-10-09
CA2789738C (en) 2021-03-09
JP2013528567A (ja) 2013-07-11
CN102811782A (zh) 2012-12-05
EP2977088A1 (en) 2016-01-27
US20130203962A1 (en) 2013-08-08
ES2641896T3 (es) 2017-11-14
EP2544785A1 (en) 2013-01-16

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Address after: uppsala

Applicant after: Situofan Biotechnology R & D Co., Ltd

Address before: uppsala

Applicant before: GE HEALTHCARE BIOPROCESS R&D AB