CN107674822A - A kind of instrument for extracting nucleic acid - Google Patents
A kind of instrument for extracting nucleic acid Download PDFInfo
- Publication number
- CN107674822A CN107674822A CN201711143468.6A CN201711143468A CN107674822A CN 107674822 A CN107674822 A CN 107674822A CN 201711143468 A CN201711143468 A CN 201711143468A CN 107674822 A CN107674822 A CN 107674822A
- Authority
- CN
- China
- Prior art keywords
- base
- nucleic acid
- instrument
- frame
- magnetically attractive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000007523 nucleic acids Chemical class 0.000 title claims abstract description 39
- 102000039446 nucleic acids Human genes 0.000 title claims abstract description 39
- 108020004707 nucleic acids Proteins 0.000 title claims abstract description 39
- 230000005291 magnetic effect Effects 0.000 claims abstract description 38
- 238000003756 stirring Methods 0.000 claims abstract description 34
- 238000000605 extraction Methods 0.000 claims abstract description 31
- 238000011068 loading method Methods 0.000 claims abstract description 30
- 239000000463 material Substances 0.000 claims abstract description 23
- 230000033001 locomotion Effects 0.000 claims abstract description 14
- 230000000694 effects Effects 0.000 claims abstract description 8
- 239000000758 substrate Substances 0.000 claims description 28
- 238000010438 heat treatment Methods 0.000 claims description 20
- 230000005540 biological transmission Effects 0.000 claims description 3
- 238000010276 construction Methods 0.000 abstract description 5
- 239000000284 extract Substances 0.000 abstract description 5
- 239000003153 chemical reaction reagent Substances 0.000 description 10
- 239000011324 bead Substances 0.000 description 8
- 238000009434 installation Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 230000005298 paramagnetic effect Effects 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 238000000354 decomposition reaction Methods 0.000 description 2
- 238000009423 ventilation Methods 0.000 description 2
- 238000005406 washing Methods 0.000 description 2
- 238000007400 DNA extraction Methods 0.000 description 1
- 239000012445 acidic reagent Substances 0.000 description 1
- 238000005336 cracking Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000003793 prenatal diagnosis Methods 0.000 description 1
- 239000012085 test solution Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
- C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
- C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The present invention provides a kind of instrument for extracting nucleic acid, including a base, the extraction assembly that is arranged on base and the housing unit for covering extraction assembly, extraction assembly includes a workbench being arranged on base, workbench is arranged on the loading component on base assembly including a base assembly and one, loading component can opposite base component or so back and forth movement, the rear of loading component is provided with a frame, agitating device and magnetically attractive device are provided with frame, agitating device includes puddle support, the stirring consumptive material being arranged on puddle support, magnetically attractive device includes magnetic frame, the magnetic bar being arranged on magnetic frame, stirring consumptive material includes some stirring rod corresponding with deep-well plates, stirring rod axle center is provided with the magnetically attractive blind hole of opening upwards, magnetic bar can be inserted into magnetically attractive blind hole.The present invention is simple in construction, simple to operate, can conveniently and efficiently extract nucleic acid, and extraction efficiency is high, effect is good, and can solve the pollution condition that extraction process is likely to occur well.
Description
Technical field
The present invention relates to a kind of instrument for extracting nucleic acid.
Background technology
With the popularization of genetic test, Personalized Drug Administration, pre-natal diagnosis etc., high pass is all pursued in each field of biological industry
Amount, today of automation, the limitation of traditional DNA extraction method is more and more obvious.Because paramagnetic particle method extraction nucleic acid can be realized certainly
Dynamicization extract, carry out high-volume operation, and it is simple to operate, the used time is short, thus paramagnetic particle method extraction nucleic acid increasingly receive attention.
At present on the market there is also some automatic nucleic acid extraction apparatuses, but these extraction apparatuses on the whole mostly it is complicated,
Extraction process is not cumbersome, easy to operate, and can not solve the pollution condition being likely to occur during nucleic acid extraction.
The content of the invention
The defects of to overcome above-mentioned prior art, the embodiments of the invention provide a kind of instrument for extracting nucleic acid, its is simple in construction,
It is simple to operate, nucleic acid can be conveniently and efficiently extracted, extraction efficiency is high, effect is good, and it is possible to solve extraction process well
The pollution condition of appearance.
In order to achieve the above object, there is provided a kind of instrument for extracting nucleic acid, including a base, the extraction assembly that is arranged on base
And the housing unit of extraction assembly is covered, extraction assembly includes a workbench being arranged on base, and workbench includes a base
Holder assembly and one loading component on base assembly is arranged on, loading component is used to place deep-well plates, and loading component can be relative
Base assembly or so back and forth movement, the rear of loading component are provided with a frame, and agitating device and magnetically attractive dress are provided with frame
Put, stirring consumptive material, the stirring driving dress of driving puddle support up and down motion that agitating device includes puddle support, is arranged on puddle support
Put, magnetically attractive device includes the magnetically attractive driving dress that magnetic frame, the magnetic bar being arranged on magnetic frame, driving magnetic frame move up and down
Put, stirring consumptive material includes some stirring rod corresponding with deep-well plates, and stirring rod axle center is provided with the magnetically attractive blind hole of opening upwards, magnetic
Power rod can be inserted into magnetically attractive blind hole.
Preferably, front and rear guide rails are provided with left and right sides of base, front and rear sliding block, base assembly are provided with front and rear guide rails
It is arranged on front and rear sliding block.
Preferably, a portal frame is provided with above base assembly, frame is arranged on portal frame.
Preferably, agitating device also includes a upper/lower guide being vertically arranged in frame and is slidably arranged in upper/lower guide
On travelling carriage, puddle support is arranged on the lower end of travelling carriage, and magnetically attractive drive device is arranged on the top of travelling carriage, the one of magnetic frame
End is connected with sliding block on one, and upper sliding block is slidably arranged on upper/lower guide.
Preferably, mixer drive is moved up and down by the first belt-driven travelling carriage, and magnetically attractive drive device passes through
The upper sliding block of second transmission belt driving moves up and down.
Preferably, loading component includes a mounting seat, and mounting seat is provided with a receiving space, be provided with receiving space to
The heating component of deep-well plates heating, is provided with an objective table above heating component, is provided with objective table and some is used for inlay card
The mounting groove of deep-well plates, mounting groove are internally provided with the through hole passed through for heating component, if two sides of mounting seat are provided with
The first connecting hole is done, the first connection blind hole corresponding with the first connecting hole is provided with the downside of the side of objective table two.
Preferably, base assembly includes first substrate, second substrate and is arranged between first substrate and second substrate
Support member, be provided with one stroke hole on first substrate, left and right back and forth movement is provided with second substrate moves horizontally component,
Moving horizontally component includes left and right rail, the left and right sliding block being movably arranged on left and right rail, driving left and right sliding block back and forth movement
Horizontal drive apparatus, left and right sliding block is arranged on below stroke hole, and loading component is connected with left and right sliding block, is provided with support member
Some second connecting holes, the second connection blind hole corresponding with the second connecting hole is provided with the downside of first substrate, first substrate
Downside setting is fluted, and projection corresponding with groove is provided with support member.
Preferably, a ventilating system is provided with housing unit, ventilating system includes an inlet scoop and an air outlet, air draught
Mouth is arranged on above loading component, and air outlet is arranged on the rear board of housing unit, and inlet scoop is a suspended hood, suspended hood cover
Firmly loading component, the upper end of suspended hood are provided with an opening, a pipe-line system are provided between opening and air outlet.
Preferably, some air vents are provided with base, air vent is located at below suspended hood.
Preferably, a lock assembly is provided with base, a locked groove is provided with workbench, lock assembly includes one and lock
The electromagnetic actuator device that the latch hook and driving latch hook that groove matches are swung up and down in locked groove.
The present invention compared with prior art the advantages of be：
The present invention is simple in construction, simple to operate, can conveniently and efficiently extract nucleic acid, and extraction efficiency is high, effect is good, and can
Solves the pollution condition that extraction process is likely to occur well.
Brief description of the drawings
Fig. 1 is the integrally-built outside schematic diagram of instrument for extracting nucleic acid；
Fig. 2 is the decomposed structural representation of the present invention；
Fig. 3 is the structural representation of agitating device and magnetically attractive device；
Fig. 4 is the structural representation of workbench；
Fig. 5 is the structural representation of objective table；
Fig. 6 is the decomposition texture schematic diagram of objective table；
Fig. 7 is the decomposition texture schematic diagram of workbench；
Fig. 8 is the structural representation of ventilating system.
Embodiment
In the present description, the orientation of the instruction such as term " on ", " under ", " preceding " and " rear " or position relationship are based on attached
Orientation or position relationship shown in figure, it is for only for ease of the description present invention rather than requires that the present invention must be with specific orientation
Construction and operation, therefore be not considered as limiting the invention.
The embodiment of the present invention is described further below in conjunction with the accompanying drawings.
Referring to figs. 1 to Fig. 3, a kind of instrument for extracting nucleic acid, including a base 1, the extraction assembly and cover that are arranged on base 1
The firmly housing unit 3 of extraction assembly, housing unit 3 include a main casing, be arranged on the sliding door 31 of lower section on front side of main casing, with
And the console 8 of main casing front side top is arranged on, a clear glass is provided among sliding door 31, directly can be seen from outside
The extraction assembly in housing unit 3 is observed, console 8 is a visual console 8, can control the running of instrument for extracting nucleic acid.
Preferably, extraction assembly includes one and is arranged on workbench 2 on base 1, workbench 2 include a base assembly 21 and
One is arranged on the loading component 22 on base assembly 21, and loading component 22 is used to place deep-well plates, and loading component 22 can be with respect to base
The back and forth movement of holder assembly 21 or so, the rear of loading component 22 are provided with a frame 4, and agitating device 5 is provided with frame 4 and is inhaled
Magnetic device 6, agitating device 5 include puddle support 51, the stirring consumptive material being arranged on puddle support 51, driving puddle support 51 and moved up and down
Mixer drive 52, the chute 511 of installation stirring consumptive material is provided with puddle support 51, stirring consumptive material is inserted or pull out into cunning
Groove 511 can conveniently and efficiently be completed to stir the installation and dismounting of consumptive material, and magnetically attractive device 6 includes magnetic frame 61, is arranged on magnetic force
The magnetically attractive drive device 63 that magnetic bar 62, driving magnetic frame 61 on frame 61 move up and down, stirring consumptive material include some and deep hole
Stirring rod corresponding to plate, stirring rod axle center are provided with the magnetically attractive blind hole of opening upwards, and magnetic bar 62 can be inserted into magnetically attractive blind hole, corresponding
Ground, stirring consumptive material are distributed with magnetic bar 62 and ordered array, are corresponded with the body of deep-well plates, so as in the cycle once tested
The interior nucleic acid extraction that can complete multigroup sample, substantially increases nucleic acid extraction efficiency.
What instrument for extracting nucleic acid of the present invention was taken is that paramagnetic particle method automatically extracts nucleic acid, and deep-well plates are placed on loading component 22, deep
Reagent and sample are housed inside orifice plate, run when instrument for extracting nucleic acid works according to the program of setting, mixer drive 52 drives
Puddle support 51, which declines, to be driven inside stirring consumptive material insertion deep-well plates, and magnetically attractive drive device 63 drives magnetic frame 61 to decline and drives magnetic force
In the magnetically attractive blind hole of the insertion stirring consumptive material of rod 62, so as to draw the magnetic bead in test solution.Consumptive material is stirred by stirring driving dress
52 are put to drive up and down and move up and down repeatedly in deep-well plates and complete stirring to reagent and sample with uniformly, cracking, washing
Used during washing, elute etc., magnetically attractive device 6 draws magnetic bead mainly during magnetic bead shifts, i.e., magnetic bead is from one
The body of deep-well plates is into the body of another deep-well plates, and during horizontal transfer, agitating device 5 and magnetically attractive device 6 are simultaneously
Do not move horizontally, but realized by the horizontal movement of loading component 22.Because the division of labor of each component is clear and definite, motion mutually matches
Close so that this nucleic acid-extracting apparatus is simple in construction, compact, easily operated with safeguarding, substantially increases the efficiency of nucleic acid extraction
With effect.
Reference picture 3, Fig. 4 and Fig. 7, preferably, the top of base assembly 21 are provided with a portal frame 7, frame 4
The left and right sides for being arranged on the upper bed-plate 1 of portal frame 7 is provided with front and rear guide rails 11, and front and rear sliding block 12 is provided with front and rear guide rails 11,
Base assembly 21 is arranged on front and rear sliding block 12, and the pull bar being arranged on base assembly 21 is connected with sliding door 31, when from outside
When opening sliding door 31, sliding door 31 drives base assembly 21 outwards to be skidded off along front and rear guide rails 11 by pull bar, so as to convenient
Staff collects the deep-well plates on objective table and reagent and extract etc. in deep-well plates, is also convenient for staff toward load
Deep-well plates and addition reagent, sample are installed on thing component 22 and change stirring consumptive material etc., and is arranged on base assembly 21
The portal frame 7 of side is reserved outside requisite space for the movable of base assembly 21, and frame 4 can also be arranged on portal frame 7,
So that the layer of structure of instrument for extracting nucleic acid is clearly demarcated, compact.
Reference picture 3, preferably, agitating device 5 also include a He of upper/lower guide 53 being vertically arranged in frame 4
The travelling carriage 54 being slidably arranged on upper/lower guide 53, puddle support 51 are arranged on the lower end of travelling carriage 54, magnetically attractive drive device 63
The top of travelling carriage 54 is arranged on, one end of magnetic frame 61 is connected with sliding block on one 64, and upper sliding block 64 is slidably arranged in
On lower guideway 53., can be complete well while the structure make it that agitating device 5 makes full use of the confined space with magnetically attractive device 6
Inserted into magnetic bar 62 in the stirring blind hole of stirring consumptive material, so as to which magnetic bead to be drawn to the outer surface of stirring consumptive material, when needing to carry out
Magnetic bead shifts, and magnetic bead need to move at the beginning from deep-well plates, the state of the remains stationary of magnetically attractive device 6 motion, and mixer drive 52 is logical
When crossing travelling carriage 54 and driving stirring consumptive material to move upwards to depart from deep-well plates, travelling carriage 54 drives the overall disengaging of magnetically attractive device 6 simultaneously
Deep-well plates, in this process, magnetic bar 62 keep geo-stationary with stirring consumptive material, are attracted on so as to ensure on stirring consumptive material
Magnetic bead does not come off from the outer surface of stirring consumptive material, ensures the effect and efficiency of the complete of nucleic acid extraction and extraction.
In addition, preferably, mixer drive 52 is moved up and down by the first belt-driven travelling carriage 54, inhale
Magnetic drive unit 63 drives upper sliding block 64 to move up and down by the second transmission belt.It is driven by conveyer belt, favorably and magnetic
The steady and smooth of power rod 62 and stirring consumptive material moves up and down.
Reference picture 5 and Fig. 6, preferably, loading component 22 include a mounting seat 221, and mounting seat 221 is provided with one
Receiving space, the heating component 222 to deep-well plates heating is provided with receiving space, the top of heating component 222 is provided with one
Objective table 223, some mounting grooves 2232 for inlay card deep-well plates is provided with objective table 223, the inside of mounting groove 2232 is set
The through hole 2231 passed through for heating component 222 is equipped with, the edge of objective table 223 is provided with the flange 2233 to raise up, installs
Two sides of seat 221 are provided with some first connecting holes 2211, and objective table is provided with and the first connecting hole on the downside of 223 liang of sides
First connection blind hole corresponding to 2211.During actual installation, mounting seat 221 is arranged on base assembly 21, and heating component 222 is installed
In installation, objective table 223 is enclosed in heating component 222 from top to bottom, and is placed in mounting seat 221, then with screw under
Up through the first connecting hole 2211 and the first connection blind hole, so as to which objective table 223 is fixed in mounting seat 221.Installation is deep
During orifice plate, directly by deep-well plates downside inlay card in mounting groove 2232, and during deep-well plates installation, insert and add on the downside of deep-well plates
In hot component 222, so that heating component 222 heats to the object in deep space plate.
Preferably, heating component 222 includes bottoming hole 2221 corresponding with deep-well plates and longitudinally through heating
The mounting hole 2222 of the bottom of hole 2221, bar-shaped heating member is provided with mounting hole 2222, and adjacent bottoming hole 2221 is intersecting.Peace
Dress is, in bottoming hole 2221 corresponding to the body insertion that deep-well plates needs are heated, and because adjacent bottoming hole 2221 is intersecting,
Body compartment on the downside of deep-well plates is every can insert bottoming hole 2221 so that in limited space, the body energy of deep-well plates
Enough accommodate more reagents and inserted deeper into ground in bottoming hole 2221, ensure the ground heating effect of heating component 222 and body
Interior temperature of reagent it is uniform.Meanwhile bottoming hole 2221 be arranged side by side it is corresponding with deep-well plates so that instrument for extracting nucleic acid can be once same
The multigroup nucleic acid extractions of Shi Jinhang, and the nucleic acid reagent temperature of different groups can be consistent.
Reference picture 7, base assembly 21 include first substrate 211, second substrate 212 and be arranged on first substrate 211 with
Support member 213 between second substrate 212, one stroke hole 2111 is provided with first substrate 211, is set on second substrate 212
Have left and right back and forth movement moves horizontally component, and moving horizontally component includes left and right rail 214, is movably arranged on left and right rail
Left and right sliding block 215, the horizontal drive apparatus 216 of the driving back and forth movement of left and right sliding block 215 on 214, left and right sliding block 215 are arranged on
The lower section of stroke hole 2111, loading component 22 are connected with left and right sliding block 215.The size in stroke hole 2111 is less than the big of mounting seat 221
It is small, after mounting seat 221 is connected with left and right sliding block 215, when the driving loading of horizontal drive apparatus 216 component 22 moves left and right, installation
Seat 221 remains to that stroke hole 2111 is completely covered, and when realizing that objective table 223 moves left and right, can place excessive reagent and flow into base
In holder assembly 21.
Preferably, some second connecting holes 2131 are provided with support member 213, the downside of first substrate 211 is set
It is equipped with and 2131 corresponding second connection blind hole of the second connecting hole；The downside of first substrate 211 sets fluted, support member 213
On be provided with projection corresponding with groove；Second substrate 212 is arranged on a front and rear sliding block that can be slid back and forth；Support member 213
Upper pivot joint is provided with a pull bar 217.During actual installation so that groove is corresponding with projection, and the second connecting hole 2131 is connected with second
Blind hole is corresponding, and then screw is connected blind hole so as to which first substrate 211 be pacified through the second connecting hole 2131 with second from the bottom up
On support member 213 so that any screw and screw hole is not present in the surface of first substrate 211, can further prevent excessive
Actually remain on first substrate 211, prevent from polluting.In addition, when workbench 2 needs movable, pull bar 217 is pulled to cause
Workbench 2 slides along front and rear sliding block, and due to setting fluted and projection between first substrate 211 and support member 213,
When workbench 2 moves forward and backward, the stress between support member 213 and first substrate 211 is mainly realized by groove and projection, so as to
The screw between the second connecting hole 2131 and the second connection blind hole is prevented to be pulled off.
Reference picture 8, preferably, a ventilating system is provided with housing unit 3, ventilating system includes an inlet scoop
With an air outlet, inlet scoop is arranged on the top of loading component 22, and air outlet is arranged on the rear board of housing unit 3, inlet scoop
For a suspended hood 32, suspended hood 32 covers loading component 22, and the upper end of suspended hood 32 is provided with an opening, opening and air outlet it
Between be provided with a pipe-line system 33.The reagent aspiration of volatilization can be discharged into specific space in time and be handled by ventilating system,
The different volatilizations of reagent one will be extracted and avoid mixing from chemically reacting, and avoid polluting.The ventilation system setups are simple, peace
Dressing is easy, and ventilation effect is good, and blower fan both may be mounted in instrument for extracting nucleic acid, can be external again, versatility is high.
Preferably, some air vents 13 are provided with base 1, air vent 13 is located at the lower section of suspended hood 32.This is logical
Air port coordinates the air further improved in instrument for extracting nucleic acid with ventilating system, further prevents reagent from the dirt that intersects occur
The situation of dye.
Reference picture 4, preferably, a lock assembly 9 is provided with base 1, a locked groove is provided with workbench 2
91, lock assembly 9 includes the electromagnetism that a latch hook 92 to match with locked groove 91 and driving latch hook 92 are swung up and down in locked groove 91
Drive device 93.The driving switch of electromagnetic actuator device 93 can be arranged on housing unit 3, by lower switch, electromagnetic drive dress
Put 93 driving latch hooks 92 to be swung up departing from locked groove 91, so as to which workbench 2 is pulled out.By lower switch certain time
Afterwards, electromagnetic actuator device 93 drives latch hook 92 to hook locked groove 91 to lower swing automatically, so as to locking workbench 2.
The announcement and teaching of book according to the above description, those skilled in the art in the invention can also be to above-mentioned embodiment party
Formula is changed and changed.Therefore, the invention is not limited in embodiment disclosed and described above, to the present invention's
Some modifications and changes should also be as falling into the scope of the claims of the present invention.In addition, although used in this specification
Some specific terms, but these terms are merely for convenience of description, do not form any restrictions to the present invention.
Claims (10)
- A kind of 1. instrument for extracting nucleic acid, it is characterised in that：It includes a base, the extraction assembly being arranged on base and covers institute The housing unit of extraction assembly is stated, the extraction assembly includes a workbench being arranged on base, and the workbench includes one Base assembly and one loading component on the base assembly is arranged on, the loading component is used to place deep-well plates, described Loading component can relatively described base assembly or so back and forth movement, the rear of the loading component be provided with a frame, the machine Be provided with agitating device and magnetically attractive device on frame, the agitating device include puddle support, the stirring consumptive material being arranged on puddle support, The mixer drive for driving puddle support to move up and down, the magnetically attractive device include magnetic frame, the magnetic force being arranged on magnetic frame The magnetically attractive drive device that rod, driving magnetic frame move up and down, the stirring consumptive material include some stirring rod corresponding with deep-well plates, The stirring rod axle center is provided with the magnetically attractive blind hole of opening upwards, and the magnetic bar can be inserted into the magnetically attractive blind hole.
- 2. instrument for extracting nucleic acid as claimed in claim 1, it is characterised in that：Front and rear lead is provided with left and right sides of the base Rail, front and rear sliding block is provided with the front and rear guide rails, and the base assembly is arranged on the front and rear sliding block.
- 3. instrument for extracting nucleic acid as claimed in claim 1 or 2, it is characterised in that：A dragon is provided with above the base assembly Door frame, the frame are arranged on the portal frame.
- 4. instrument for extracting nucleic acid as claimed in claim 1, it is characterised in that：The agitating device is also vertically arranged in institute including one The upper/lower guide in frame and the travelling carriage being slidably arranged on upper/lower guide are stated, the puddle support is arranged on the travelling carriage Lower end, the magnetically attractive drive device are arranged on the top of the travelling carriage, and one end of the magnetic frame is connected with sliding block on one, The upper sliding block is slidably arranged on the upper/lower guide.
- 5. instrument for extracting nucleic acid as claimed in claim 4, it is characterised in that：The mixer drive is driven by the first conveyer belt The dynamic travelling carriage moves up and down, and the magnetically attractive drive device drives the upper sliding block to move up and down by the second transmission belt.
- 6. instrument for extracting nucleic acid as claimed in claim 1, it is characterised in that：The loading component includes a mounting seat, the peace Dress seat is provided with a receiving space, and the heating component to deep-well plates heating, the heating component are provided with the receiving space Top be provided with an objective table, some mounting grooves for inlay card deep-well plates, the mounting groove are provided with the objective table Be internally provided with the through hole passed through for the heating component, two sides of the mounting seat are provided with some first connecting holes, The first connection blind hole corresponding with first connecting hole is provided with the downside of the side of objective table two.
- 7. instrument for extracting nucleic acid as claimed in claim 1, it is characterised in that：The base assembly includes first substrate, the second base Plate and the support member being arranged between first substrate and second substrate, one stroke hole is provided with the first substrate, it is described The component that moves horizontally of left and right back and forth movement is provided with second substrate, the component that moves horizontally includes left and right rail, activity Left and right sliding block, the horizontal drive apparatus of driving left and right sliding block back and forth movement being arranged on left and right rail, the left and right sliding block are set Put below the stroke hole, the loading component is connected with the left and right sliding block, and some second are provided with the support member Connecting hole, the second connection blind hole corresponding with second connecting hole, first base are provided with the downside of the first substrate The downside setting of plate is fluted, and projection corresponding with the groove is provided with the support member.
- 8. instrument for extracting nucleic acid as claimed in claim 1, it is characterised in that：A ventilating system is provided with the housing unit, The ventilating system includes an inlet scoop and an air outlet, and the inlet scoop is arranged on above loading component, and the air outlet is set Put on the rear board of the housing unit, the inlet scoop is a suspended hood, and the suspended hood covers loading component, the suction The upper end of fan housing is provided with an opening, and a pipe-line system is provided between the opening and air outlet.
- 9. instrument for extracting nucleic acid as claimed in claim 8, it is characterised in that：Some air vents are provided with the base, it is described Air vent is located at below the suspended hood.
- 10. instrument for extracting nucleic acid as claimed in claim 1, it is characterised in that：A lock assembly is provided with the base, it is described A locked groove is provided with workbench, the lock assembly includes a latch hook to match with the locked groove and the driving latch hook exists The electromagnetic actuator device swung up and down in locked groove.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711143468.6A CN107674822A (en) | 2017-11-17 | 2017-11-17 | A kind of instrument for extracting nucleic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711143468.6A CN107674822A (en) | 2017-11-17 | 2017-11-17 | A kind of instrument for extracting nucleic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107674822A true CN107674822A (en) | 2018-02-09 |
Family
ID=61149938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711143468.6A Pending CN107674822A (en) | 2017-11-17 | 2017-11-17 | A kind of instrument for extracting nucleic acid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107674822A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103897987A (en) * | 2014-02-18 | 2014-07-02 | 中国农业大学 | Automatic extraction device and method of nucleic acid based on nano magnetic beads |
| CN103923163A (en) * | 2013-01-15 | 2014-07-16 | 北京金麦格生物技术有限公司 | Workbench system and the method for bioactive substance extractor |
| CN107058062A (en) * | 2017-06-09 | 2017-08-18 | 苏州天隆生物科技有限公司 | A kind of rotary nucleic acid-extracting apparatus and its control method |
| CN107118958A (en) * | 2017-07-13 | 2017-09-01 | 上海奇法生物仪器有限公司 | Nucleic acid purifier |
| CN207483723U (en) * | 2017-11-17 | 2018-06-12 | 广州瑞能医学科技有限公司 | A kind of instrument for extracting nucleic acid |
-
2017
- 2017-11-17 CN CN201711143468.6A patent/CN107674822A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103923163A (en) * | 2013-01-15 | 2014-07-16 | 北京金麦格生物技术有限公司 | Workbench system and the method for bioactive substance extractor |
| CN103897987A (en) * | 2014-02-18 | 2014-07-02 | 中国农业大学 | Automatic extraction device and method of nucleic acid based on nano magnetic beads |
| CN107058062A (en) * | 2017-06-09 | 2017-08-18 | 苏州天隆生物科技有限公司 | A kind of rotary nucleic acid-extracting apparatus and its control method |
| CN107118958A (en) * | 2017-07-13 | 2017-09-01 | 上海奇法生物仪器有限公司 | Nucleic acid purifier |
| CN207483723U (en) * | 2017-11-17 | 2018-06-12 | 广州瑞能医学科技有限公司 | A kind of instrument for extracting nucleic acid |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111004797B (en) | Nucleic acid extraction device and nucleic acid extraction method | |
| CN103923163B (en) | Workbench system and the method for bioactive substance extractor | |
| CN106867883B (en) | Automatic nucleic acid extraction instrument | |
| CN203174009U (en) | Working platform system for bioactive substance extraction instrument | |
| CN110819623A (en) | Nucleic acid extraction instrument and extraction method | |
| CN103992940B (en) | A kind of instrument extracting biologically active substance | |
| CN207483723U (en) | A kind of instrument for extracting nucleic acid | |
| CN105021441B (en) | Automatic smear overflow dyeing machine | |
| CN105936873B (en) | A kind of cleaning structure of hybridization instrument | |
| CN105733942B (en) | A kind of device for nucleic acid extraction | |
| CN107674822A (en) | A kind of instrument for extracting nucleic acid | |
| CN203238267U (en) | Bioactive substance extractor | |
| CN209584238U (en) | Magnetic method nucleic acid automatic extracting device | |
| CN203855572U (en) | Instrument for extracting active substance of organisms | |
| CN210079529U (en) | Modified starch's heating reaction unit | |
| CN210113279U (en) | Novel nucleic acid extraction appearance | |
| KR20220083797A (en) | portable bioreactor | |
| CN217265654U (en) | Nucleic acid extraction device | |
| CN210113275U (en) | Anti-pollution nucleic acid extraction system | |
| CN207567428U (en) | A kind of head, rotating shuttle independent driving automobile sunshade front sewing device | |
| CN211848004U (en) | Nucleic acid extraction instrument | |
| CN109929757A (en) | A kind of novel nucleic acids extraction apparatus | |
| CN207987170U (en) | Dewaxing device for extracting sample from FFPE histotomies | |
| CN108004234A (en) | A kind of Rapid nucleic acid extraction equipment | |
| CN114276910A (en) | Nucleic acid extraction and purification instrument |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20180209 |