CN107669757A - Promote dressing of wound healing and preparation method thereof - Google Patents
Promote dressing of wound healing and preparation method thereof Download PDFInfo
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- CN107669757A CN107669757A CN201710896198.XA CN201710896198A CN107669757A CN 107669757 A CN107669757 A CN 107669757A CN 201710896198 A CN201710896198 A CN 201710896198A CN 107669757 A CN107669757 A CN 107669757A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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Abstract
The present invention relates to dressing for promoting wound healing and preparation method thereof, belong to wound care technical field.Present invention solves the technical problem that it is to provide the dressing for promoting wound healing.The dressing active component is made up of the component of following parts by weight:20~30 parts of radix scutellariae;20~30 parts of Ligusticum wallichii;10~25 parts of the fruit of Chinese magnoliavine;10~25 parts of the coptis;10~20 parts of pseudo-ginseng;10~15 parts of bitter melon seed;10~18 parts of centella;5~10 parts of radix glycyrrhizae;Fresh 5~10 parts of peppermint.The dressing of the present invention is rapid-action, the effect for can be rapidly achieved hemostasis, relieving the pain, and promotes wound healing;It is made of natural Chinese medicinal herb, excitant, toxic side effect is small;Preparation method is simple, and cost is low.
Description
Technical field
The present invention relates to dressing for promoting wound healing and preparation method thereof, belong to wound care technical field.
Background technology
Skin is the vitals of human body, has highly important physics, chemistry and biological barrier function, playing prevents water
Point and the material such as electrolyte loss, and the function such as immune, sensing, to maintaining the stabilization of vivo environment and preventing microorganism from entering
Invade and play a very important role.The skin injury caused by the reasons such as wound, burn and exanthemv, body one can be caused
The problem of serial, for example bacterium infection, metabolism aggravation, moisture and protein are excessively lost in, endocrine and immune system work(
Can lack of proper care etc., serious possibility threat to life.Therefore, after skin injury, it usually needs according to selecting in various degree for wound
The medical instrument used, prevents trauma surface infestation and serious dehydration, there is provided is advantageous to the moist environment of wound healing, promotes the surface of a wound to be cured
Close.The method of in the market treatment wound mainly has powdery type medicine, adhesive bandage, ointments medicine and paste dressing etc..
Traditional dressing such as medical absorbent cotton gauze, cotton pad and petrolatum gauze etc. at present, it is clinically skin trauma application
Most wide dressing.Traditional dressing has netted braiding structure, its is cheap, manufacture craft is relatively easy, raw material sources are extensive,
Soft texture, there is stronger absorbability, can prevent wound exudate from gathering, there is a certain degree of protective effect to wound healing,
So far the extensive use still in skin trauma.But traditional dressing also has the shortcomings that apparent, for example the surface of a wound can not be kept to moisten,
Postpone wound healing;Wound granulation tissue is easily in the mesh of long people's dressing, during more change dressings easily with wound adhesion, damage
The granulation tissue of new life simultaneously causes pain;Barrier action is poor after dressing infiltration, easily causes exogenous infection, and haemostatic effect is poor.
Therefore, it is badly in need of a kind of dressing that can rapidly promote wound healing.
The content of the invention
Present invention solves the technical problem that it is to provide the dressing for promoting wound healing.
The present invention promotes the dressing of wound healing, and its active component is made up of the component of following parts by weight:Radix scutellariae 20~30
Part;20~30 parts of Ligusticum wallichii;10~25 parts of the fruit of Chinese magnoliavine;10~25 parts of the coptis;10~20 parts of pseudo-ginseng;10~15 parts of bitter melon seed;Accumulated snow
10~18 parts of grass;5~10 parts of radix glycyrrhizae;Fresh 5~10 parts of peppermint.
Preferably, its active component is made up of the component of following parts by weight:22~27 parts of radix scutellariae;21~26 parts of Ligusticum wallichii;Five
12~18 parts of taste;11~22 parts of the coptis;13~16 parts of pseudo-ginseng;11~14 parts of bitter melon seed;12~16 parts of centella;Radix glycyrrhizae 6~9
Part;Fresh 7~10 parts of peppermint.
Preferably, its active component is made up of the component of following parts by weight:25 parts of radix scutellariae;24 parts of Ligusticum wallichii;The five tastes
16 parts of son;18 parts of the coptis;14 parts of pseudo-ginseng;13 parts of bitter melon seed;16 parts of centella;7 parts of radix glycyrrhizae;Fresh 8 parts of peppermint.
Second technical problem that the present invention solves is to provide the preparation method of the dressing of above-mentioned promotion wound healing.
The present invention promotes the preparation method of the dressing of wound healing, comprises the following steps:
A, radix scutellariae, Ligusticum wallichii, the fruit of Chinese magnoliavine, the coptis, pseudo-ginseng, bitter melon seed, centella, radix glycyrrhizae and fresh peppermint are taken, after being mixed,
Clay into power;
B, mixed-powder obtained by a steps is added into distilled water, and heating and refluxing extraction, cooling, obtains extract solution;
C, extract solution is concentrated into paste, adds sesame oil and mix thoroughly, Chinese medicine ointment is made, that is, promotes the dressing of wound healing.
Preferably, in b step, the time of heating and refluxing extraction is 30~120min.
It is further preferred that the time of heating and refluxing extraction is 60min.
Preferably, in b step, according to solid-liquid ratio 1:3~6g/mL adds water.
Preferably, in b step, according to solid-liquid ratio 1:5g/mL adds water.
Compared with prior art, the present invention has the advantages that:
1) dressing of the invention is rapid-action, the effect for can be rapidly achieved hemostasis, relieving the pain, and promotes wound healing.
2) dressing of the invention, is made, excitant, toxic side effect is small of natural Chinese medicinal herb.
3) dressing preparation method of the present invention is simple, and cost is low.
Embodiment
The present invention promotes the dressing of wound healing, and its active component is made up of the component of following parts by weight:Radix scutellariae 20~30
Part;20~30 parts of Ligusticum wallichii;10~25 parts of the fruit of Chinese magnoliavine;10~25 parts of the coptis;10~20 parts of pseudo-ginseng;10~15 parts of bitter melon seed;Accumulated snow
10~18 parts of grass;5~10 parts of radix glycyrrhizae;Fresh 5~10 parts of peppermint.
Preferably, its active component is made up of the component of following parts by weight:22~27 parts of radix scutellariae;21~26 parts of Ligusticum wallichii;Five
12~18 parts of taste;11~22 parts of the coptis;13~16 parts of pseudo-ginseng;11~14 parts of bitter melon seed;12~16 parts of centella;Radix glycyrrhizae 6~9
Part;Fresh 7~10 parts of peppermint.
Preferably, its active component is made up of the component of following parts by weight:25 parts of radix scutellariae;24 parts of Ligusticum wallichii;The five tastes
16 parts of son;18 parts of the coptis;14 parts of pseudo-ginseng;13 parts of bitter melon seed;16 parts of centella;7 parts of radix glycyrrhizae;Fresh 8 parts of peppermint.
The dressing of the promotion wound healing of the present invention, is prepared using the Chinese medicine of particular types and weight, each
Complemented each other between component, Synergistic so that pharmaceutical composition of the present invention can be very good to promote wound healing.
Alias Radix Scutellariae, the tsuchikane tea root of radix scutellariae, the root of radix scutellariae are used as medicine, bitter, cold in nature, have heat-clearing and damp-drying drug, purging intense heat and detonicating,
Hemostasis, antiabortive and other effects.Cure mainly warm heat disease, the infection of the upper respiratory tract, cough with lung heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery, hemoptysis, mesh
The diseases such as red, fetal irritability, hypertension, carbuncle swells furuncle sore.The clinical antibiotic property of radix scutellariae is better than the coptis, and does not develop immunity to drugs.
Ligusticum wallichii (scientific name:Ligusticum chuanxiong hort), cultivated plant, main product is in Sichuan (Guanxian county), in cloud
The ground such as south, Guizhou, Guangxi, it is grown on gentle climatic environment.It is a kind of Chinese medicinal plant, is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping,
Ligusticum wallichii pungent-warm perfume (or spice) is dry, walks without keeping, and can go scattered, up reachable mountain peak top;Enter blood system, the descending reachable sea of blood again.Promoting blood circulation is made
With extensive, the suitable various illnesss of stagnation of blood stasis;Wind-expelling pain-stopping, effectiveness is favourable, can control the diseases such as head wind headache, arthralgia pain due to rheumatism.Former times people
It is the gas medicine in blood to call Ligusticum wallichii, nearly says its function such as pungent scattered, Xie Yu, sensible, analgesic of residing.
The fruit of Chinese magnoliavine is the dry mature fruit of magnoliaceae schisandra.Plucked during autumn fruit maturation, after drying or steaming
Dry, remove carpopodium and impurity.Tang etc.《Tang materia medica》" five tastes skin and flesh sweet acid, work hard in core, there is saline taste " is carried, therefore there are the five tastes
The name of son.The fruit of Chinese magnoliavine is divided into two kinds of south, north.Ancient medical book Cheng Ta Chinese magnoliavines, Chinese magnoliavine, meeting and, be listed in earliest in Sheng Nong's herbal classic top grade
Medicine, the power of energy strengthening by means of tonics, medical value is high, there is the effect of physical fitness, and treatment insomnia is shared with fine jade treasure ganoderma lucidum.
The coptis, (scientific name:Coptis chinensis Franch.) alias:Taste connects, river connects, Rhizoma Coptidis, category Ranunculaceae, Huang
Even category herbaceos perennial, phyllopodium are hesitated, and hard papery, ovate triangle, three totally cleave, central sliver ovate rhombus, pinniform drastic crack,
There is sharp sawtooth at edge, and life sliver in side does not wait 2 drastic cracks;The long 5-12cm of petiole.It is wild or cultivate in height above sea level 1000-1900m mountain valley
In cool wet concealment thick forest.There is the effect of heat-clearing and damp-drying drug, purging intense heat and detonicating.
Pseudo-ginseng also known as pseudo-ginseng, it is Umbellales Araliaceae, is distributed mainly on the ground such as Yunnan, Guangxi, Jiangxi, Sichuan.Together
Name Chinese medicine pseudo-ginseng is using the root of plant pseudo-ginseng as medicinal effects, has the effect of dissipate stasis of blood hemostasis, detumescence ding-tong.Cure mainly and cough up
Blood, spit blood, bleeding from five sense organs or subcutaneous tissue, have blood in stool, uterine bleeding, traumatism and bleeding, chest and abdomen shouting pain, fall servant's swelling and pain.
Bitter melon seed is the seed of cucurbitaceous plant balsam pear.Moisture content 8.6%, ash content 21.8%, fiber 19.5%, carbon aquation
Thing 16.4%, fat oil 31.0%.Contain butyric acid 1.8% in oil, palmitic acid 2.8%, stearic acid 21.7%, oleic acid 30.0%, α-
Eleostearic acid 43.7%.Have the function that QI invigorating, enriching yin, fall fire, disappear fire, relieve summer heat, hypoglycemic, cool blood, be described as glucokinin.
Centella, also known as membranaceous marshmarigold herb, certain herbaceous plants with big flowers Peng Lai, chipping bowl, Longtube Ground Ivy Herb, Lao Gonggen, lopseed, perennial draft of crawling.
Stem is very thin to throw oneself on the ground, hairless or slightly hair, is taken root on section.Single leaf alternate, blade is circular or kidney shape, above it is smooth, the back side has thin soft
Hair, there are rough sawn tooth or cognate in edge;Petiole base sheath shape, no stipule.Umbel list is raw or 2~5 fasciations, bennet are born in leaf
Armpit, each bennet top spend 3~6 to be polymerized to capitulum;Phyllary 2, sepal butt shape;Petal 5, avette, aubergine, top
Hold micro- curve inwardly;5 pieces of stamen is short and small;Ovary is the next, and style 2 is shorter.Diachenium is oblate, smooth, main ridge shape.Its water
Decoction has antiulcer, antibacterial action;Asiaticosid has calm, stable effect to rat, mouse;Alcohol extracting thing can relax rat
Ileum From A White.Wound healing can be promoted.
Radix glycyrrhizae alias state is old, Herba Hedyotis cantonensis, Glycyrrhiza Uralensis, sweet tea root.Pulse family, Glycyrrhiza perennial herb, root and root-like stock
It is sturdy, it is a kind of help Chinese herbal medicine.To human body, a kind of medicine, medicinal part are root and rhizomes well, and Medicinal Materials Characters root is in cylinder
Shape, long 25~100 centimetres, 0.6~3.5 centimetre of diameter.Crust is elastic to differ, surface rufous or taupe brown.Rhizome is in cylinder
There is bud scar on shape, surface, has marrow in the middle part of section.Gas is micro-, sweet and special.Major function is clearing heat and detoxicating, expelling phlegm and arresting coughing, gastral cavity abdomen etc..
Fresh peppermint is fresh dried peppermint leaf.Peppermint is one of Chinese conventional Chinese medicine.It is pungent cool property sweating antipyretic medicine, controls stream
The diseases such as row sexuality emits, the swelling and pain of headache, hot eyes, body heat, throat, gum.External application can control neuralgia, pruitus, fash and eczema
Deng.Usually with peppermint for tea, clear away heart-fire improving eyesight.
After the dressing of the present invention is boiled using above-mentioned Chinese medicine, worked in coordination between each composition, can be very good to promote wound
Mouth healing.
The present invention promotes the preparation method of the dressing of wound healing, comprises the following steps:
A, radix scutellariae, Ligusticum wallichii, the fruit of Chinese magnoliavine, the coptis, pseudo-ginseng, bitter melon seed, centella, radix glycyrrhizae and fresh peppermint are taken, after being mixed,
Clay into power;
B, mixed-powder obtained by a steps is added into distilled water, and heating and refluxing extraction, cooling, obtains extract solution;
C, extract solution is concentrated into paste, adds sesame oil and mix thoroughly, Chinese medicine ointment is made, that is, promotes the dressing of wound healing.
Wherein, in a steps, the powder of various crude drugs also can be directly taken, is mixed.
Preferably, in b step, the time of heating and refluxing extraction is 30~120min.
It is further preferred that the time of heating and refluxing extraction is 60min.
Preferably, in b step, according to solid-liquid ratio 1:3~6g/mL adds water.
Preferably, in b step, according to solid-liquid ratio 1:5g/mL adds water.
The embodiment of the present invention is further described with reference to embodiment, therefore not limited the present invention
System is among described scope of embodiments.
Embodiment 1
Radix scutellariae, Ligusticum wallichii, the fruit of Chinese magnoliavine, the coptis, pseudo-ginseng, bitter melon seed, centella, radix glycyrrhizae and fresh peppermint are taken, after being mixed, mill
Into powder;100g powder is taken by solid-liquid ratio 1:3g/mL adds water, and heating and refluxing extraction 30min, obtains extract solution;By extract solution
Paste is concentrated into, sesame oil is added and mixes thoroughly, Chinese medicine ointment is made, that is, promotes the dressing of wound healing.
Wherein, the formula of each medicinal material is:20 parts of radix scutellariae;30 parts of Ligusticum wallichii;10 parts of the fruit of Chinese magnoliavine;25 parts of the coptis;20 parts of pseudo-ginseng;It is bitter
10 parts of melon seeds;18 parts of centella;5 parts of radix glycyrrhizae;Fresh 10 parts of peppermint.
The dressing is rapid-action, the effect for can be rapidly achieved hemostasis, relieving the pain, and promotes wound healing.And excitant, toxic side effect
It is small.
Embodiment 2
Radix scutellariae, Ligusticum wallichii, the fruit of Chinese magnoliavine, the coptis, pseudo-ginseng, bitter melon seed, centella, radix glycyrrhizae and fresh peppermint are taken, after being mixed, mill
Into powder;100g powder is taken by solid-liquid ratio 1:6g/mL adds water, and heating and refluxing extraction 120min, obtains extract solution;By extract solution
Paste is concentrated into, sesame oil is added and mixes thoroughly, Chinese medicine ointment is made, that is, promotes the dressing of wound healing.
Wherein, the formula of each medicinal material is:30 parts of radix scutellariae;20 parts of Ligusticum wallichii;25 parts of the fruit of Chinese magnoliavine;10 parts of the coptis;10 parts of pseudo-ginseng;It is bitter
15 parts of melon seeds;10 parts of centella;10 parts of radix glycyrrhizae;Fresh 5 parts of peppermint.
The dressing is rapid-action, the effect for can be rapidly achieved hemostasis, relieving the pain, and promotes wound healing.And excitant, toxic side effect
It is small.
Embodiment 3
Radix scutellariae, Ligusticum wallichii, the fruit of Chinese magnoliavine, the coptis, pseudo-ginseng, bitter melon seed, centella, radix glycyrrhizae and fresh peppermint are taken, after being mixed, mill
Into powder;100g powder is taken by solid-liquid ratio 1:5g/mL adds water, and heating and refluxing extraction 60min, obtains extract solution;By extract solution
Paste is concentrated into, sesame oil is added and mixes thoroughly, Chinese medicine ointment is made, that is, promotes the dressing of wound healing.
Wherein, the formula of each medicinal material is:22 parts of radix scutellariae;26 parts of Ligusticum wallichii;18 parts of the fruit of Chinese magnoliavine;11 parts of the coptis;16 parts of pseudo-ginseng;It is bitter
14 parts of melon seeds;12 parts of centella;9 parts of radix glycyrrhizae;Fresh 7 parts of peppermint.
The dressing is rapid-action, the effect for can be rapidly achieved hemostasis, relieving the pain, and promotes wound healing.And excitant, toxic side effect
It is small.
Embodiment 4
Radix scutellariae, Ligusticum wallichii, the fruit of Chinese magnoliavine, the coptis, pseudo-ginseng, bitter melon seed, centella, radix glycyrrhizae and fresh peppermint are taken, after being mixed, mill
Into powder;100g powder is taken by solid-liquid ratio 1:5g/mL adds water, and heating and refluxing extraction 60min, obtains extract solution;By extract solution
Paste is concentrated into, sesame oil is added and mixes thoroughly, Chinese medicine ointment is made, that is, promotes the dressing of wound healing.
Wherein, the formula of each medicinal material is:27 parts of radix scutellariae;21 parts of Ligusticum wallichii;12 parts of the fruit of Chinese magnoliavine;22 parts of the coptis;13 parts of pseudo-ginseng;It is bitter
11 parts of melon seeds;16 parts of centella;6 parts of radix glycyrrhizae;Fresh 10 parts of peppermint.
The dressing is rapid-action, the effect for can be rapidly achieved hemostasis, relieving the pain, and promotes wound healing.And excitant, toxic side effect
It is small.
Embodiment 5
Radix scutellariae, Ligusticum wallichii, the fruit of Chinese magnoliavine, the coptis, pseudo-ginseng, bitter melon seed, centella, radix glycyrrhizae and fresh peppermint are taken, after being mixed, mill
Into powder;100g powder is taken by solid-liquid ratio 1:5g/mL adds water, and heating and refluxing extraction 60min, obtains extract solution;By extract solution
Paste is concentrated into, sesame oil is added and mixes thoroughly, Chinese medicine ointment is made, that is, promotes the dressing of wound healing.
Wherein, the formula of each medicinal material is:25 parts of radix scutellariae;24 parts of Ligusticum wallichii;16 parts of the fruit of Chinese magnoliavine;18 parts of the coptis;14 parts of pseudo-ginseng;It is bitter
13 parts of melon seeds;16 parts of centella;7 parts of radix glycyrrhizae;Fresh 8 parts of peppermint.
The dressing is rapid-action, the effect for can be rapidly achieved hemostasis, relieving the pain, and promotes wound healing.And excitant, toxic side effect
It is small.
Claims (8)
1. promote the dressing of wound healing, it is characterised in that its active component is made up of the component of following parts by weight:Radix scutellariae 20~
30 parts;20~30 parts of Ligusticum wallichii;10~25 parts of the fruit of Chinese magnoliavine;10~25 parts of the coptis;10~20 parts of pseudo-ginseng;10~15 parts of bitter melon seed;Product
10~18 parts of snow grass;5~10 parts of radix glycyrrhizae;Fresh 5~10 parts of peppermint.
2. the dressing according to claim 1 for promoting wound healing, it is characterised in that by the component system of following parts by weight
Into:22~27 parts of radix scutellariae;21~26 parts of Ligusticum wallichii;12~18 parts of the fruit of Chinese magnoliavine;11~22 parts of the coptis;13~16 parts of pseudo-ginseng;Bitter melon seed
11~14 parts;12~16 parts of centella;6~9 parts of radix glycyrrhizae;Fresh 7~10 parts of peppermint.
3. the dressing according to claim 2 for promoting wound healing, it is characterised in that by the component system of following parts by weight
Into:25 parts of radix scutellariae;24 parts of Ligusticum wallichii;16 parts of the fruit of Chinese magnoliavine;18 parts of the coptis;14 parts of pseudo-ginseng;13 parts of bitter melon seed;16 parts of centella;Radix glycyrrhizae 7
Part;Fresh 8 parts of peppermint.
4. the preparation method of the dressing of the promotion wound healing described in any one of claims 1 to 3, it is characterised in that including such as
Lower step:
A, radix scutellariae, Ligusticum wallichii, the fruit of Chinese magnoliavine, the coptis, pseudo-ginseng, bitter melon seed, centella, radix glycyrrhizae and fresh peppermint are taken, after being mixed, is worn into
Powder;
B, mixed-powder obtained by a steps is added into distilled water, and heating and refluxing extraction, cooling, obtains extract solution;
C, extract solution is concentrated into paste, adds sesame oil and mix thoroughly, Chinese medicine ointment is made, that is, promotes the dressing of wound healing.
5. the preparation method of the dressing of promotion wound healing according to claim 4, it is characterised in that:In b step, heating
The time of refluxing extraction is 30~120min.
6. the preparation method of the dressing of promotion wound healing according to claim 5, it is characterised in that:In b step, heating
The time of refluxing extraction is 60min.
7. the preparation method of the dressing of the promotion wound healing according to claim 4 or 5, it is characterised in that:In b step,
According to solid-liquid ratio 1:3~6g/mL adds water.
8. the preparation method of the dressing of promotion wound healing according to claim 7, it is characterised in that:In b step, according to
Solid-liquid ratio 1:5g/mL adds water.
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CN105770732A (en) * | 2016-03-15 | 2016-07-20 | 李素琴 | Medicament for eliminating swelling |
CN106389687A (en) * | 2016-11-07 | 2017-02-15 | 海南医学院 | Preparation method of Li medical callicarpa nudiflora scald ointment |
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CN1977926A (en) * | 2006-11-30 | 2007-06-13 | 荆树汉 | Crude drug for promoting wound quick healing and its preparation |
CN102266546A (en) * | 2011-08-26 | 2011-12-07 | 天津尖峰弗兰德医药科技发展有限公司 | Externally used Chinese herbal preparation for treating frostbite and preparation method thereof |
CN103656372A (en) * | 2013-10-07 | 2014-03-26 | 刘景文 | Diabetic foot ointment |
CN105267508A (en) * | 2015-11-02 | 2016-01-27 | 余椿 | Tianqi black ointment, Tianqi spray and Tianqi Chinese herbal bag capable of eliminating Bi-complex pain |
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Application publication date: 20180209 |