CN107668715A - A kind of food additives with regulation blood glucose effect and application - Google Patents

A kind of food additives with regulation blood glucose effect and application Download PDF

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CN107668715A
CN107668715A CN201711040034.3A CN201711040034A CN107668715A CN 107668715 A CN107668715 A CN 107668715A CN 201711040034 A CN201711040034 A CN 201711040034A CN 107668715 A CN107668715 A CN 107668715A
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flower
hours
blood glucose
conditions
food additives
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张奎昌
张志年
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Xuzhou Lvzhiye Biological Foodstuff Co Ltd
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Xuzhou Lvzhiye Biological Foodstuff Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A21BAKING; EDIBLE DOUGHS
    • A21DTREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D13/00Finished or partly finished bakery products
    • A21D13/06Products with modified nutritive value, e.g. with modified starch content
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/14Yeasts or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
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Abstract

There are the food additives of regulation blood glucose effect the invention particularly discloses a kind of, be 1 by plants and flowers and jerusalem artichoke it is characterized in that using dry product plants and flowers, jerusalem artichoke as raw material:35 part by weight, through crushing, soaking, digesting, compound bacteria-fermented, water extraction, alcohol extracting, filtering and concentrating, drying, the technique such as crushing is made.The technique recovery rate that the present invention uses is high, utilization rate is high, the food additives being prepared into can be widely used in the product of varieties of food items, drink, wine product, flavouring and nutriment, product category extracted form natural plant product of the present invention, long-term consumption will not produce adverse side effect, it is a kind of food supplement with healthcare function, there is good application prospect.

Description

A kind of food additives with regulation blood glucose effect and application
Technical field
The invention belongs to food processing field, is related to food additives field, and in particular to there is one kind regulation blood glucose to make The application of food additives and the food additives.
Background technology
Food processing field be unable to do without food additives, in order to ensure characteristic, mouthfeel and the quality safety of processed food, its Flavor enhancement, preservative, antioxidant, anticaking agent, leavening agent etc. are indispensable, in order to improve the outward appearance of food and taste, Its food coloring, essence and flavoring agent are also conventional additive, in order to improve and lifted nutritive value of food, in food processing Nutrition fortifier can be added, the nutrition fortifier that China's food processing enterprises are commonly used in food processing at present is mostly amino acid The materials such as class, vitamins, macroelement, trace element and fatty acid, application of these additives in food processing, it is The varieties of food items that manufactures and guarantee the quality serves the application of important function, particularly nutrition fortifier, to improve nutritive value of food, Ensure that the health of people serves highly important effect.It can be seen that in the food additives that can be used from existing disclosure Mostly it is its chemical substance or its chemically synthesized product, then lacks for natural sex animal and plant food additives very few.China has The ancient civilization culture of more than 5000 years, traditional Chinese medicine are one of rarities of China's culture, have the article of dietotherapeutic resource quite rich Richness, dietotherapeutic resource be people in long-term production, practical experience of life, be widely used as food material to utilize, but again simultaneously With certain prevention or some disease effects for the treatment of, partly the agriculture of some characteristics with similar medicine, woods, aquatic products provide Source." doctor's food homology " theory is China working people production, accumulation of the experience of life in thousands of years, is the knot of ancestor's group wisdom It is brilliant.Modem medical practices show that containing abundant having in these dietotherapeutic resources strengthens body defenses function, regulation people Body circadian rhythm, the generation for preventing some diseases reduce its initiation potential, promote the physiologically active ingredients such as patient health recovery, It is the primary raw material of functional food exploitation, there is wide exploitation prospect.
With the development of science and technology China is obtained for significant progress, the life of the people in the various aspects of society Level is significantly improved, and this provides unprecedented opportunity to develop for whole food industry.At the same time, due to industry Development, population increase it is too fast and caused by living environment deteriorate, air and water resource pollution aggravation and diet collocation not science etc. Reason, China resident suffer from the ratio of the diseases such as malignant tumour, hyperlipidemia, high blood pressure, artery sclerosis, diabetes, obesity Example rises year by year, and morbidity object is also gradually to the development that becomes younger.The increase of national income and the raising of the level of consumption, cause people again Have stronger consuming capacity, it is sufficient to pay the of a relatively high spending of wholesome functional food.It is all these all to form There is the fast-developing very strong driving force of functional food processing industry, and dietotherapeutic resource is then with functional food life The most important raw material of production.The progress of diet largely indicates a national overall qualities and social development water Flat, the cooking culture in China once made significant contribution to world's diet the reach of science, particularly diet promote health, Achievement acquired by dietotherapeutic food resource use aspects more catches people's attention.But because modern age is in economic, culture and science The development in the fields such as technology relatively lags behind, China's modern diet scientific level, the work(particularly in traditional dietotherapeutic resource The scientific knowledge of composition and reasonable use aspects are imitated, are fallen behind some developed countries.Reform and open up to the outside world over 30 years, with The horizontal rapid raising of China's socio-economic development, the people have begun to pay attention to changing some less rational diet in the past Custom, " science eaten, the health of work, work it is permanent " have become the generally pursuit of people.Therefore, traditional dietotherapeutic is provided Source makes full use of, and food additives of the exploitation with functional components effect, has to the development for promoting China's food manufacturing There is preferable realistic meaning, to avoid or reducing using chemicals food additives, ensure people's safe diet and lift me The competitiveness of state's food and functional food in the world is respectively provided with significance.However, constantly carrying with people's living standard Height, the requirement of nutrition and safety to food are also continuously increased, and requirement of the people to food is also just progressively to " safe and non-toxic, battalion The green non-pollution that the direction of foster health care, back to nature " is developed, it is using the jerusalem artichoke with regulation blood glucose effect and plants and flowers Raw material, a kind of food additives with regulation blood glucose effect are prepared, and the additive is widely used in varieties of food items, In drink product, in wine product, in seasoning, people are made to obtain beneficial nutrition work(in eating or drinking these product Effect, it will by the people for pursuing health, particularly there is hyperglycaemia and the welcome of diabetic.
The content of the invention
It is an object of the invention to provide a kind of food addition and application with regulation blood glucose effect, selection are same using medicine food Source and rich in inulin, synanthrin, natural jerusalem artichoke and the edible plants flowers to blood glucose with dual regulation are raw material, It is prepared into and is widely used in varieties of food items, drink, wine product, the food additives with regulation blood glucose of flavouring, meets People while enjoying delicious adjusted blood glucose, regulation organism balance, enhance metabolism, prevention disease, safeguard human body The effect of healthy.
In order to realize the present invention, following technical scheme is specifically employed:
According to a kind of food additives that there is regulation blood glucose to act on of the present invention, dry product plants and flowers, jerusalem artichoke is used to be pressed for raw material Plants and flowers, jerusalem artichoke 1:3-5 part by weight, is made up of following methods:
(1)The dry product plants and flowers and clean dry product jerusalem artichoke for weighing cleaning respectively are crushed, and cross 200-300 mesh sieves, respectively Plants and flowers powder and jerusalem artichoke powder;
(2)Inserted after plants and flowers powder, jerusalem artichoke powder are mixed in proportion in fermentation tank, add the pure water of 10 times of weight of raw material, Stir, be heated to 40 DEG C of -42 DEG C of heat-insulation soakings two hours, obtain slurry;
(3)To step(2)Weight is added in slurry than the complex enzyme for 1-2%, 3-5 hours are digested under 40 DEG C of constant temperatures, so Afterwards by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, enzymolysis liquid is obtained;
(4)By step(3)Sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, it is 10-12% to add raw material weight ratio Compound agglomeration, under the conditions of 36 DEG C -38 DEG C ferment 10-12 hours, obtain zymotic fluid;
(5)Stirred 1 time every two hours in fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, by zymotic fluid be heated to 95-98 DEG C insulation 2.5-3 hours extracted, be then in centrifugal rotational speed 5000r/min, filter screen are centrifugal filtration under the conditions of 500 purposes, collect filtrate, and filter residue enters tank, adds the pure of 5 times of raw material weight Water, it is heated to 100 DEG C and boils 1 hour to re-start extraction, is then 5000r/min in centrifugal rotational speed, filter screen is 500 condition Lower centrifugal filtration obtains filter residue and filtrate respectively, filtrate will merge twice, and obtain aqueous extract;
(7)To step(6)Filter residue in, the ethanol that raw material 6-8 times of weight content is 60%V/V is added, under the conditions of 40-50 DEG C Refluxing extraction twice, is extracted 2-3 hours for the first time, second of extraction 1-1.5 hour, is in centrifugal rotational speed after extraction every time 5000r/min, filter screen are centrifugal filtration under the conditions of 500 purposes, collect filtrate twice, merge to obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate is concentrated into paste under the conditions of 50-80 DEG C, -0.065MPa~-0.1MPa;
(11)By step(10)Gained plaster material, under the conditions of 50 DEG C -90 DEG C, 32-42 hours are dried, obtain siccative;
(12)By step(11)Gained siccative is cooled to room temperature, crushed, and the material after crushing crosses 100 mesh sieves, obtains powdered food Product additive.
Here is the further optimization and/or selection to above-mentioned technical proposal:
Described plants and flowers be white twigs of the chaste tree flower, citrus flower, Flores tiliae, lychee flower, sesame flower, cotton, Chinese tallow tree, by tree Flower, water banyan, nightshade, firecracker flower, butterflybush flower, magnolia(Flower bud), poplar Chinese holly flower(Male inflorescence), ponceau, oyster plant inflorescence, west Szechwan pyrethrum flower Flower, flos longan, lily, honeysuckle, chrysanthemum, chrysanthemum indicum, snow chrysanthemum, marigold, flower of kudzuvine, sophora flower, Pagoda Flower, jujube flower, russianolive flower, Ginkgo, peach blossom, apricot flower, rose, gardenia, Jasmine, Flos Hibisci Mutabilis, sweet osmanthus, safflower, hops, betelnutpalm male flower, shrub althea flower, Yulan magnolia, lotus, pomegranate flower, sanchi flower, salvia miltiorrhiza flower, China rose, azalea, bitter tattooing, Panzhihua flower, plum blossom, dahurian rose flower, stone Bamboo, forget-me-not flower, lavandulae flos, camellia, lilac, peony, strawberry, Radix Isatidis flower, rape flower, Flos Forsythiae, aloe Flower, multiple hedgehogcactus flower, Radix Angelicae Sinensis flower, platycodon flower, beggar's buttons, Ligusticum wallichii flower, Chinese ilex, Chinese magnoliavine flower, pumpkin flower, radix glycyrrhizae, Snakegourd Fruit flower, Mustard, Zijin lotus flower, Ulex flower, Chinese photinia flower, Chinese flowering crabapple, bodhi, ditch wintercherry flower, anthemidis flos, peppermint flower, Flos Albiziae, Peony, gillyflower, rosemary flower, Roselle, SEMEN OROXYLI flower, globe amaranth, the lemon showy flowers of herbaceous plants, Agrimony flower, balsamine, iron Line lotus flower, pot marigold, the rough gentian showy flowers of herbaceous plants, cyani flos, pear flower, sponge gourd flower, rose, flower of hyacinth dolichos, pine tree, pea flowers, ginseng Flower, showy flowers of herbaceous plants tomorrow, caulis bambusae in taenian flower, fleeceflower flower, gynostemma pentaphylla, barrenwort flower, eclipta, the accumulated snow showy flowers of herbaceous plants, sealwort flower, the banksia rose Flower, shell of seaear flower, Flos Platycladi, American lotus, wormwoodlike motherwort flower, Chinese mosla flower, SEMEN SINAPIS ALBAE flower, cordate houttuynia, balm flower, witloof, Chinese torreya Sub- flower, mulberry tree, purple perilla flower, Jiang Hua, Buckwheat Flower, sunflower, small thistle, red paeony flower, punching lotus flower, Chinese violet, chrysanthemum Chinese violet, Flos Lycii, May bloom, dark plum flower, cablin patchouli flower, sea-buckthorn, Flos Semen Lablab Album, radix scrophulariae flower, Flos Magnoliae Officinalis, cymose buckwheat rhizome flower, Huang Stilbene flower, Echinacea flower, the Patrinia scaniosaefolia showy flowers of herbaceous plants, a string of safflowers, cockscomb, oriental cherry, cherry blossom, balsam pear flower, jerusalem artichoke flower, orchid, Flos Mume, Kamuning flower, india canna flower, Flos Hibisci Rosae-Sinensis, tree orchid, spearmint, fringed iris, Chinese lute flower, Flos Magnoliae Liliflorae, finger citron flower, Michelia figo, Common rush, pith flower, glutinous rice fragrant flower, wooden red bayberry, tawny daylily, white dead nettle, popcorn, lehua, broom top, coltsfoot Flower, ivy glorybind, big thistle, tulip, honeysuckle, frost flower, by chrysanthemum, by the showy flowers of herbaceous plants, small beautiful flower, okra, Zhulan tree Flower, bitter citrus immature flower, oriental wormwood, sweetleaf chrysanthemum, flower of JINHUAKUI, raspberry flower, stem of noble dendrobium flower, blueberry flower, one kind in Siberian elm leaf plum blossom or two Kind any of the above combination.
Above-mentioned steps(1)Described crushing is ultramicro grinding;Described ultramicro grinding preferably uses vibration superfine disintegrator.
Above-mentioned steps(3)Pectase that it is 2000u/g by unit of activity that described complex enzyme, which is, unit of activity 5000u/ The cellulase that g fungal amylase and unit of activity is 2000u/g is 1 by weight:2:1 ratio compound forms.
Above-mentioned steps(3)Described compound agglomeration is by weight being 1 by saccharomycete and lactic acid bacteria:1 proportions Composition.
Saccharomycete described above is the brewer's yeast of food commercially available, brewer's yeast, candida tropicalis, production Any one viable bacteria dry powder product in protein Candida and Saccharomyces cerevisiae.
Lactic acid bacteria described above be edible lactobacillus acidophilus commercially available, lactobacillus thermophilus, lactobacillus bulgaricus, Any one viable bacteria dry powder product in Bifidobacterium, streptococcus thermophilus and Pediococcus acidilactici.
Above-mentioned steps(9)In preferable concentration condition be 60 DEG C -70 DEG C, -0.07MPa~-0.09MPa.
Above-mentioned steps(9)Described concentration from vacuum rotary evaporator, tubular type evaporation concentrator or pull formula evaporation it is dense Contracting device.
Above-mentioned steps(10)Described drying condition is that 38-42 hours are dried under the conditions of 70 DEG C -80 DEG C.
Above-mentioned steps(10)Described drying uses heated-air drying, far-infrared ray drying or microwave drying.
According to a kind of food additives that there is regulation blood glucose to act on of the present invention, due to the work combined using water extraction and alcohol extracting Skill, its water-soluble functional component and fat-soluble organic principle are maximumlly extracted, its nutritional ingredient than single water or Wanting for alcohol extracting is high more, and because the flavor in flowers is mostly alcohol-soluble composition, only water extraction is that difficulty can be extracted fully Out, can preferably be solved the above problems using the technique for combining alcohol extracting.Jerusalem artichoke is rich in starch, is commonly called as inulin or synanthrin, It is a kind of macromolecule polysaccharide, water-soluble, but be dissolved in water synanthrin add ethanol when just by being precipitated in the aqueous solution, this Characteristic determine the invention adopt the technology that first with water extraction contained synanthrin and other water soluble ingredients are fully extracted after Again with its liposoluble constituent of alcohol extracting, the water soluble ingredient such as synanthrin first caused by alcohol extracting can be so avoided to fill Divide extraction and/or cause to precipitate and make the adverse effect of nutrient loss.Due to the technique used in the present invention, using enzyme Seldom part of the techniques such as solution, compound bacteria-fermented, water extraction, alcohol extracting, its water and alcohol insoluble matter impurity is then other as waste residue Utilize, and the technique recovery rate that the present invention uses is high, product is obtained the extraction of high-purity, on the contrary extraction and application rate Height, the additive output object weight is 30% of raw material weight or so.
The water in raw material and Alcohol soluble composition are subjected to purification utilization because the present invention adopts the technology that, so than using The dosage of plasm raw material is reduced, and the bad smell of plasm raw material is also not present, beneficial to the addition prepared in food and not Influence the taste and quality of products made thereby.The food additives that the present invention has regulation blood glucose effect are pressed into 3%-9% weight percents Than addition, can add applied in varieties of food items.It is used for example as basic staple food such as steamed bun, noodles, steamed bun etc., baking cake such as The additive of such as ham sausage, canned pork luncheon meat in bread, biscuit, Layer cake, style snacks and meat products food.
The present invention has the food additives of regulation blood glucose effect, due to being extracted by water, alcohol combined process, first, extraction Purity is high, and in addition extract dissolubility is good, and it can also be used to process wine product product by 3-9% percentage by weights addition, such as The white wine rich in additive of the present invention, grape wine, beer, yellow rice wine, fruit wine etc. is made, example takes additive 3kg of the present invention to be added to In 97kg white wine, stir, ageing dispenses after 60 days through filtering, and obtained color is orange, as clear as crystal, fragrant in taste, order The colony for liking drinking adds the new kind of health liquor.
Because product dissolubility of the present invention is good, can also by 3-9% percentage by weights addition adding as processing and seasoning product Add agent, such as soy sauce, vinegar, sweet tea sauce, flour paste, mayonnaise, thick chilli sauce, chafing dish bottom flavorings, can also add in nutriment Such as solid beverage(Granule), tablet, micellar etc..The application of the above scope can according to conventional methods add and be not required to spy Different technique, thus application of the product of the present invention in food processing is provided conveniently.
Plants and flowers not only beautiful outward appearance, but also contain several physiological active substances, aromatic substance and flavones, class The materials such as carrotene.The nutrition of flowers and special nutritive value are increasingly valued by the people, and are people's biostearin, mineral One of main source of matter, organic acid and aromatic substance etc..The often intense strain of the edible people that can relax, also beauty, be good for skin, The effect of stimulating circulation etc..Drink made from flower is new natural flower beverage a kind of in recent years, and this drink made from flower is without thorn Swash property material, not only color, fragrance make us pleasing for it, and the work(with Glycerin, beautifying face and moistering lotion and spirit refreshing and eye-brightening Effect, is especially favored by female consumer.Flower nutrition food not only maintains the characteristic of food, and is also convenient for food Digest, also contain various aromatic oil and organic acid in flowers, improved after different food is processed into different ways The peculiar flavour of different product.Due to containing various volatile flavors in flowers, it is various special just to generate Flavor, so as to add the desire of people's edible flower food.
Modern study confirms in flowers to contain compared with the amino acid of horn of plenty, vitamin, mineral matter and trace element, goes back simultaneously Containing bioactive ingredients such as fat, nucleic acid, growth factor, enzyme material and antibacterial substances, there is scholar's research report, flowers are also Pharmacological function with uniqueness, many flowers not only have the effect of clearing heat and detoxicating, qi-regulating blood-nourishing, also refresh oneself with clear mesh, are good for The function of stomach, strengthen immunity, frequent edible flower can relax the intense strain of people, also beauty, strong skin, promote blood to follow Ring etc. acts on.A small amount of natural flower drink, food are popular in market in recent years.Exploitation more contains flower nutrition function Food and drink be that people live the requirement improved constantly, and health of people, the pursuit of vigorous and graceful life.However, these are produced Product can not all be generalizable because of season, territorial environment, the limitation of source of goods channel, be hardly formed the generality of market comsupton, Therefore, researching and developing a kind of food additives product, the health food not by season in season and territory restriction is provided to people Additive come meet health of people life the needs of.
Jerusalem artichoke(Scientific name Helianthus tuberosusL.)Also known as Jerusalem artichoke, it is a kind of perennial root herbaceous plant for many years, its Underground stem tuber is edible rich in fructose polymers such as starch, synanthrin.Traditional Chinese medicine thinks, jerusalem artichoke stem tuber:It is sweet, it is cool.Heat-clearing is cool Blood, synthetism.For hot disease, the lower blood of intestines heat, traumatic injury, quench one's thirst.Modern study finds that synanthrin can treat glycosuria contained by Jerusalem artichoke Disease, it has dual regulation to blood glucose, i.e., on the one hand can reduce blood sugar in diabetic patients, another aspect and can makes low blood Sugared glucose rise.Contain a kind of and very approximate thing of human pancreatic Li Neisheng insulin structures in studies have shown that Jerusalem artichoke Matter, when occurring glucose in urine in urine, edible Jerusalem artichoke can control glucose in urine, illustrate there is reduction sugar effect.When there is hypoglycemia in people, food With can be equally eased after Jerusalem artichoke.Containing abundant inulin in Jerusalem artichoke stem tuber, inulin is also known as synanthrin, is a kind of high score Sub- polysaccharide --- Fructooligosaccharides, it is that have low in calories and good water solubility characteristic Dietary Health food.In recent years, inulin conduct A kind of natural function dispensing is increasingly popular in field of health care food application.Reported in literature shows according to the study, ingests daily two grams Inulin prevents that some diseases, human body imbalance and disease of old people are helpful to control body weight, improvement function of intestinal canal.Inulin By nutritional supplement of the individual state approval as food more than 40 in the world.Synanthrin is the good medicine for treating diabetes again in medicine.
Jerusalem artichoke stem tuber is rich in amino acid, sugar, vitamin etc., 79.8 grams of moisture content in every 100 grams of stem tubers, 0.1 gram of crude protein, 0.1 gram of fat, 16.6 grams of carbohydrate, 0.6 gram of crude fibre, 2.8 grams of ash content, 49 milligrams of calcium, 119 milligrams of phosphorus, the milli of iron 8.4 Gram, vitamin B10.13 milligram, vitamin B20.06 milligram, 0.6 milligram of niacin, 6 milligrams of vitamin C, and containing abundant chrysanthemum The materials such as sugar, pentosan, starch.Wherein inulin(Synanthrin)And FOS because its structure it is clear and definite, physiological hygiene function is definite And turn into a kind of important functional food, confirmed through domestic and international more prominent universities and medical college's research, inulin and oligomeric fruit Sugar have the function that it is superpower propagation human body Bifidobacterium, be the functional materials beneficial to human body, it for adjust organism balance, Recover gastrointestinal function, enhance metabolism, prevent various diseases, to safeguard that health plays the role of particularly important, be 21 Century the representative typical products of human health.
The jerusalem artichoke that great nutritious plants and flowers is had dual regulation with having by the present invention to blood glucose coordinates, Through enzymolysis, microbial bacteria fermentation after, through water extraction and alcohol extracting, then concentrated and dried made from food additives, have There is DNA purity high, dosage is few, and solubility is big, and the advantages of having a wide range of application in food processing, one kind had been provided both for people The effect of with abundant nutrition and with bidirectional modulation blood glucose, this ensures health to people, prevents disease from occurring to have well Meaning.
Composite microbial bacteria fermentation in present invention process, it can effectively improve taste, mouthfeel and the quality of product, through life Thing chemically reacts, and can be converted many organic substances, its process also increases new nutriment;Pass through enzymolysis process, energy Its inulin ingredient is converted into fructose, there is lifting nutrition and improve the beneficial effect of products taste.
A kind of food additives with regulation blood glucose effect of the present invention, belong to integration of drinking and medicinal herbs using plants and flowers and jerusalem artichoke Natural plant resource, not only there is abundant natural nutrient component, while have again to blood glucose dual regulation, while chrysanthemum In taro contained abundant FOS can Bifidobacterium in Effective multiplication human body, reduce blood fat, improve lipid-metabolism, improve human body Immunologic function and other effects, to preventing various diseases, to safeguard that health plays the role of particularly important.Especially the present invention is used and taken Special technique, product free from extraneous odour, taste flavor is pure, and dissolubility is good, be widely used as varieties of food items, seasoning, wine Product, additive, basic staple food, baking cake, style snacks, jam product, soy sauce, vinegar, the additive of wine are used for example as, Available for various meat fillingss and the additive of meat product, it is alternatively arranged as nutriment and particle is directly made according to a conventional method Agent, tablet, capsule etc..Due to product category extracted form natural plant product of the present invention, particularly the synanthrin in jerusalem artichoke composition is to people Body blood glucose has dual regulation, and long-term consumption will not produce adverse side effect, and is that a kind of physiological hygiene function is definite Food supplement, there is the effect of preferable physical fitness.
Embodiment
The present invention is further illustrated with the following Examples, and the whole of non-invention, embodiment are adopted Auxiliary raw material is the food additives raw material for meeting food applications level commercially available, and its equipment is this area public affairs The conventional equipment known;For its preparation method in addition to the specific characteristic that the present invention limits, other are technical conditions well known in the art, Its procedure is unrestricted, and embodiment is not also construed as limiting the invention.
Embodiment 1
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product plants and flowers 10 and the clean ㎏ of dry product jerusalem artichoke 30 of cleaning are weighed respectively, are entered using vibration superfine disintegrator Row crushes, and crosses 200 mesh sieves, obtains plants and flowers powder and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of the plants and flowers powder 10 and ㎏ of jerusalem artichoke powder 30 is mixed in fermentation tank, adds 400 ㎏ pure water, stirring Uniformly, 40 DEG C of -42 DEG C of heat-insulation soakings are heated to 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 4.4kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 3 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, add by brewer's yeast and streptococcus thermophilus by weight Measure as 1:The compound agglomeration 4.4kg of 1 ratio composition, stirs, is fermented 12 hours under the conditions of 36 DEG C, obtain zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 95 DEG C of insulations and extracted within 3 hours, is then filtered with centrifuge using 500 mesh Net centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 200kg, is heated to 100 DEG C and boils Boiling is extracted for 1 hour, is then 5000r/min in centrifugal rotational speed, and filter screen is centrifugal filtration under the conditions of 500 purposes, respectively Filter residue and filtrate, filtrate it will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 240kg, refluxing extraction 2 times under the conditions of 40 DEG C, first Secondary extraction 3 hours, the 2nd extraction 1 hour, every time in the bar that centrifugal rotational speed is 5000r/min, filter screen is 500 mesh after extraction Centrifugal filtration under part, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 60 DEG C, -0.09MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 70 DEG C, dry 42 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 2
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product plants and flowers 10 and the clean ㎏ of dry product jerusalem artichoke 40 of cleaning are weighed respectively, are entered using vibration superfine disintegrator Row crushes, and crosses 250 mesh sieves, obtains plants and flowers powder and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of the plants and flowers powder 10 and ㎏ of jerusalem artichoke powder 40 is mixed in fermentation tank, adds 500 ㎏ pure water, stirring Uniformly, 40 DEG C of -42 DEG C of heat-insulation soakings are heated to 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 8.25kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 4 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, add by candida utili and Pediococcus acidilactici It is 1 by weight:The compound agglomeration 5.5kg of 1 ratio composition, stirs, ferments 11 hours, must ferment under the conditions of 37 DEG C Liquid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 98 DEG C of insulations and extracted within 2.5 hours, then uses 500 mesh with centrifuge Filter screen centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 250kg, is heated to 100 DEG C Boil 1 hour and extracted, be then 5000r/min in centrifugal rotational speed, filter screen is centrifugal filtration under the conditions of 500 purposes, respectively Filter residue and filtrate are obtained, filtrate will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 350kg, refluxing extraction 2 times under the conditions of 45 DEG C, first It is secondary extraction 2.5 hours, the 2nd time extract 1.5 hours, every time extraction after centrifugal rotational speed be 5000r/min, filter screen be 500 mesh Under conditions of centrifugal filtration, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 60 DEG C, -0.07MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 80 DEG C, dry 32 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 3
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product plants and flowers 10 and the clean ㎏ of dry product jerusalem artichoke 50 of cleaning are weighed respectively, are entered using vibration superfine disintegrator Row crushes, and crosses 300 mesh sieves, obtains plants and flowers powder and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of the plants and flowers powder 10 and ㎏ of jerusalem artichoke powder 50 is mixed in fermentation tank, adds 600 ㎏ pure water, stirring Uniformly, 40 DEG C of -42 DEG C of heat-insulation soakings are heated to 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 13.2kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 5 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 38 DEG C, add by brewer's yeast and streptococcus thermophilus by weight Measure as 1:The compound agglomeration 6kg of 1 ratio composition, stirs, is fermented 10 hours under the conditions of 36 DEG C, obtain zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 97 DEG C of insulations and extracted within 2.75 hours, then uses 500 with centrifuge Mesh filter screen centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 300kg, is heated to 100 DEG C boiling 1 hour and to be extracted, be then 5000r/min in centrifugal rotational speed, filter screen is centrifugal filtration under the conditions of 500 purposes, point Filter residue and filtrate are not obtained, filtrate will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 480kg, refluxing extraction 2 times under the conditions of 50 DEG C, first It is secondary extraction 2.5 hours, the 2nd time extract 1.5 hours, every time extraction after centrifugal rotational speed be 5000r/min, filter screen be 500 mesh Under conditions of centrifugal filtration, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 65 DEG C, -0.08MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 75 DEG C, dry 37 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 4
The preparation of food additives with regulation blood glucose effect:
(1)The dry product snow chrysanthemum for weighing cleaning respectively spends 10 ㎏ and the clean ㎏ of dry product jerusalem artichoke 30, is carried out using vibration superfine disintegrator Crush, cross 200 mesh sieves, obtain snow chrysanthemum pollen and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of the snow chrysanthemum pollen 10 and ㎏ of jerusalem artichoke powder 30 is mixed in fermentation tank, adds 400 ㎏ pure water, stirring is equal It is even, it is heated to 40 DEG C of -42 DEG C of heat-insulation soakings 2 hours, obtains slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 4.4kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 3 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, add by brewer's yeast and streptococcus thermophilus by weight Measure as 1:The compound agglomeration 4kg of 1 ratio composition, stirs, is fermented 12 hours under the conditions of 36 DEG C, obtain zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 95 DEG C of insulations and extracted within 3 hours, is then filtered with centrifuge using 500 mesh Net centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 200kg, is heated to 100 DEG C and boils Boiling is extracted for 1 hour, is then 5000r/min in centrifugal rotational speed, and filter screen is centrifugal filtration under the conditions of 500 purposes, respectively Filter residue and filtrate, filtrate it will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 240kg, refluxing extraction 2 times under the conditions of 40 DEG C, first Secondary extraction 3 hours, the 2nd extraction 1 hour, every time in the bar that centrifugal rotational speed is 5000r/min, filter screen is 500 mesh after extraction Centrifugal filtration under part, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 60 DEG C, -0.09MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 70 DEG C, dry 42 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 5
The preparation of food additives with regulation blood glucose effect:
(1)Weigh respectively cleaning the ㎏ of dry product salvia miltiorrhiza flower 7, Ligusticum wallichii spend 3 ㎏ and the clean ㎏ of dry product jerusalem artichoke 40, using vibration Ultramicro-powder Broken machine is crushed, and crosses 250 mesh sieves, obtains the red sage root, Ligusticum wallichii pollen and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of red sage root pollen 7, the ㎏ of Ligusticum wallichii pollen 3 and the ㎏ of jerusalem artichoke powder 40 are mixed in fermentation tank, adds the pure of 500 ㎏ Water purification, stir, be heated to 40 DEG C of -42 DEG C of heat-insulation soakings 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 8.25kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 4 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, add by candida utili and Pediococcus acidilactici It is 1 by weight:The compound agglomeration 6kg of 1 ratio composition, stirs, ferments 11 hours, must ferment under the conditions of 37 DEG C Liquid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 98 DEG C of insulations and extracted within 2.5 hours, then uses 500 mesh with centrifuge Filter screen centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 250kg, is heated to 100 DEG C Boil 1 hour and extracted, be then 5000r/min in centrifugal rotational speed, filter screen is centrifugal filtration under the conditions of 500 purposes, respectively Filter residue and filtrate are obtained, filtrate will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 350kg, refluxing extraction 2 times under the conditions of 45 DEG C, first It is secondary extraction 2.5 hours, the 2nd time extract 1.5 hours, every time extraction after centrifugal rotational speed be 5000r/min, filter screen be 500 mesh Under conditions of centrifugal filtration, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 60 DEG C, -0.07MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 80 DEG C, dry 32 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 6
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product Flos Lycii 3, the ㎏ of May bloom 5, the ㎏ of witloof 2 and the clean ㎏ of dry product jerusalem artichoke 50 of cleaning are weighed respectively, are used Vibration superfine disintegrator is crushed, and crosses 300 mesh sieves, obtains matrimony vine, hawthorn, witloof pollen and jerusalem artichoke powder respectively;
(2)It is placed in fermentation tank, adds after the ㎏ of matrimony vine pollen 3, the ㎏ of Hawthorn Pollen 5, the ㎏ of witloof pollen 2 and the ㎏ of jerusalem artichoke powder 50 are mixed Enter 600 ㎏ pure water, stir, be heated to 40 DEG C of -42 DEG C of heat-insulation soakings 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 13.2kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 5 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 38 DEG C, add by brewer's yeast and streptococcus thermophilus by weight Measure as 1:The compound agglomeration 7.2kg of 1 ratio composition, stirs, is fermented 10 hours under the conditions of 36 DEG C, obtain zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 97 DEG C of insulations and extracted within 2.75 hours, then uses 500 with centrifuge Mesh filter screen centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 300kg, is heated to 100 DEG C boiling 1 hour and to be extracted, be then 5000r/min in centrifugal rotational speed, filter screen is centrifugal filtration under the conditions of 500 purposes, point Filter residue and filtrate are not obtained, filtrate will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 480kg, refluxing extraction 2 times under the conditions of 50 DEG C, first It is secondary extraction 2.5 hours, the 2nd time extract 1.5 hours, every time extraction after centrifugal rotational speed be 5000r/min, filter screen be 500 mesh Under conditions of centrifugal filtration, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 65 DEG C, -0.08MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 75 DEG C, dry 37 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 7
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product flower of JINHUAKUI 10 and the clean ㎏ of dry product jerusalem artichoke 30 of cleaning are weighed respectively, are entered using vibration superfine disintegrator Row crushes, and crosses 200 mesh sieves, obtains Golden flower pollen and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of the Golden flower pollen 10 and ㎏ of jerusalem artichoke powder 30 is mixed in fermentation tank, adds 400 ㎏ pure water, stirring Uniformly, 40 DEG C of -42 DEG C of heat-insulation soakings are heated to 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 4.4kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 3 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, add by brewer's yeast and streptococcus thermophilus by weight Measure as 1:The compound agglomeration 4.8kg of 1 ratio composition, stirs, is fermented 12 hours under the conditions of 36 DEG C, obtain zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 95 DEG C of insulations and extracted within 3 hours, is then filtered with centrifuge using 500 mesh Net centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 200kg, is heated to 100 DEG C and boils Boiling is extracted for 1 hour, is then 5000r/min in centrifugal rotational speed, and filter screen is centrifugal filtration under the conditions of 500 purposes, respectively Filter residue and filtrate, filtrate it will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 240kg, refluxing extraction 2 times under the conditions of 40 DEG C, first Secondary extraction 3 hours, the 2nd extraction 1 hour, every time in the bar that centrifugal rotational speed is 5000r/min, filter screen is 500 mesh after extraction Centrifugal filtration under part, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 60 DEG C, -0.09MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 70 DEG C, dry 42 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 8
The preparation of food additives with regulation blood glucose effect:
(1)The dry product isatis root for weighing cleaning respectively spends 5 ㎏, the ㎏ of punching lotus flower 5 and the clean ㎏ of dry product jerusalem artichoke 40, super using vibration Atomizer is crushed, and crosses 250 mesh sieves, obtains isatis root, Herba Andrographitis pollen and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of isatis root pollen 5, the ㎏ of Herba Andrographitis pollen 5 and the ㎏ of jerusalem artichoke powder 40 are mixed in fermentation tank, adds 500 ㎏ Pure water, stir, be heated to 40 DEG C of -42 DEG C of heat-insulation soakings 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 8.25kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 4 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, add by candida utili and Pediococcus acidilactici It is 1 by weight:The compound agglomeration 5.25kg of 1 ratio composition, stirs, ferments 11 hours, must send out under the conditions of 37 DEG C Zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 98 DEG C of insulations and extracted within 2.5 hours, then uses 500 mesh with centrifuge Filter screen centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 250kg, is heated to 100 DEG C Boil 1 hour and extracted, be then 5000r/min in centrifugal rotational speed, filter screen is centrifugal filtration under the conditions of 500 purposes, respectively Filter residue and filtrate are obtained, filtrate will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 350kg, refluxing extraction 2 times under the conditions of 45 DEG C, first It is secondary extraction 2.5 hours, the 2nd time extract 1.5 hours, every time extraction after centrifugal rotational speed be 5000r/min, filter screen be 500 mesh Under conditions of centrifugal filtration, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 60 DEG C, -0.07MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 80 DEG C, dry 32 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 9
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product cordate houttuynia 5, the ㎏ of dandelion 5 of cleaning and the clean ㎏ of dry product jerusalem artichoke 50 are weighed respectively, using vibration Micronizer is crushed, and crosses 300 mesh sieves, obtains cordate houttuynia, dandelion pollen and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of cordate houttuynia pollen 5, the ㎏ of dandelion pollen 5 and the ㎏ of jerusalem artichoke powder 50 are mixed in fermentation tank, adds 600 ㎏ pure water, stirs, and is heated to 40 DEG C of -42 DEG C of heat-insulation soakings 2 hours, obtains slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 13.2kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 5 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 38 DEG C, add by brewer's yeast and streptococcus thermophilus by weight Measure as 1:The compound agglomeration 6.6kg of 1 ratio composition, stirs, is fermented 10 hours under the conditions of 36 DEG C, obtain zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 97 DEG C of insulations and extracted within 2.75 hours, then uses 500 with centrifuge Mesh filter screen centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 300kg, is heated to 100 DEG C boiling 1 hour and to be extracted, be then 5000r/min in centrifugal rotational speed, filter screen is centrifugal filtration under the conditions of 500 purposes, point Filter residue and filtrate are not obtained, filtrate will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 480kg, refluxing extraction 2 times under the conditions of 50 DEG C, first It is secondary extraction 2.5 hours, the 2nd time extract 1.5 hours, every time extraction after centrifugal rotational speed be 5000r/min, filter screen be 500 mesh Under conditions of centrifugal filtration, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 65 DEG C, -0.08MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 75 DEG C, dry 37 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 10
The preparation of food additives with regulation blood glucose effect:
(1)The dry product sealwort for weighing cleaning respectively spends 8 ㎏, the ㎏ of flower of Panax ginseng 2 and the clean ㎏ of dry product jerusalem artichoke 30, using vibration Ultramicro-powder Broken machine is crushed, and crosses 200 mesh sieves, obtains sealwort, ginseng pollen and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of solomonseal-pollen 8, the ㎏ of ginseng pollen 2 and the ㎏ of jerusalem artichoke powder 30 are mixed in fermentation tank, adds the pure of 400 ㎏ Water purification, stir, be heated to 40 DEG C of -42 DEG C of heat-insulation soakings 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 4.4kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 3 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, add by brewer's yeast and streptococcus thermophilus by weight Measure as 1:The compound agglomeration 4.8kg of 1 ratio composition, stirs, is fermented 12 hours under the conditions of 36 DEG C, obtain zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 95 DEG C of insulations and extracted within 3 hours, is then filtered with centrifuge using 500 mesh Net centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 200kg, is heated to 100 DEG C and boils Boiling is extracted for 1 hour, is then 5000r/min in centrifugal rotational speed, and filter screen is centrifugal filtration under the conditions of 500 purposes, respectively Filter residue and filtrate, filtrate it will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 240kg, refluxing extraction 2 times under the conditions of 40 DEG C, first Secondary extraction 3 hours, the 2nd extraction 1 hour, every time in the bar that centrifugal rotational speed is 5000r/min, filter screen is 500 mesh after extraction Centrifugal filtration under part, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 60 DEG C, -0.09MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 70 DEG C, dry 42 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 11
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product strawberry 7, the ㎏ of raspberry flower 3 of cleaning and the clean ㎏ of dry product jerusalem artichoke 40 are weighed respectively, using vibration Ultramicro-powder Broken machine is crushed, and crosses 250 mesh sieves, obtains strawberry, raspberry pollen and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of strawberry pollen 7, the ㎏ of raspberry pollen 3 and the ㎏ of jerusalem artichoke powder 40 are mixed in fermentation tank, adds the pure of 500 ㎏ Water purification, stir, be heated to 40 DEG C of -42 DEG C of heat-insulation soakings 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 8.25kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 4 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, add by candida utili and Pediococcus acidilactici It is 1 by weight:The compound agglomeration 5.5kg of 1 ratio composition, stirs, ferments 11 hours, must ferment under the conditions of 37 DEG C Liquid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 98 DEG C of insulations and extracted within 2.5 hours, then uses 500 mesh with centrifuge Filter screen centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 250kg, is heated to 100 DEG C Boil 1 hour and extracted, be then 5000r/min in centrifugal rotational speed, filter screen is centrifugal filtration under the conditions of 500 purposes, respectively Filter residue and filtrate are obtained, filtrate will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 350kg, refluxing extraction 2 times under the conditions of 45 DEG C, first It is secondary extraction 2.5 hours, the 2nd time extract 1.5 hours, every time extraction after centrifugal rotational speed be 5000r/min, filter screen be 500 mesh Under conditions of centrifugal filtration, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 60 DEG C, -0.07MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 80 DEG C, dry 32 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 12
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product jerusalem artichoke flower 10 and the clean ㎏ of dry product jerusalem artichoke 50 of cleaning are weighed respectively, are carried out using vibration superfine disintegrator Crush, cross 300 mesh sieves, obtain jerusalem artichoke pollen and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of the jerusalem artichoke pollen 10 and ㎏ of jerusalem artichoke powder 50 is mixed in fermentation tank, adds 600 ㎏ pure water, stirring is equal It is even, it is heated to 40 DEG C of -42 DEG C of heat-insulation soakings 2 hours, obtains slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 13.2kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 5 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 38 DEG C, add by brewer's yeast and streptococcus thermophilus by weight Measure as 1:The compound agglomeration 6.6kg of 1 ratio composition, stirs, is fermented 10 hours under the conditions of 36 DEG C, obtain zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 97 DEG C of insulations and extracted within 2.75 hours, then uses 500 with centrifuge Mesh filter screen centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 300kg, is heated to 100 DEG C boiling 1 hour and to be extracted, be then 5000r/min in centrifugal rotational speed, filter screen is centrifugal filtration under the conditions of 500 purposes, point Filter residue and filtrate are not obtained, filtrate will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 480kg, refluxing extraction 2 times under the conditions of 50 DEG C, first It is secondary extraction 2.5 hours, the 2nd time extract 1.5 hours, every time extraction after centrifugal rotational speed be 5000r/min, filter screen be 500 mesh Under conditions of centrifugal filtration, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 65 DEG C, -0.08MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 75 DEG C, dry 37 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 13
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product okra 10 and the clean ㎏ of dry product jerusalem artichoke 30 of cleaning are weighed respectively, are entered using vibration superfine disintegrator Row crushes, and crosses 200 mesh sieves, obtains okra pollen and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of the okra pollen 10 and ㎏ of jerusalem artichoke powder 30 is mixed in fermentation tank, adds 400 ㎏ pure water, stirring Uniformly, 40 ㎏ DEG C of -42 DEG C of heat-insulation soaking are heated to 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 4.4kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 3 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, add by brewer's yeast and streptococcus thermophilus by weight Measure as 1:The compound agglomeration 4.8kg of 1 ratio composition, stirs, is fermented 12 hours under the conditions of 36 DEG C, obtain zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 95 DEG C of insulations and extracted within 3 hours, is then filtered with centrifuge using 500 mesh Net centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 200kg, is heated to 100 DEG C and boils Boiling is extracted for 1 hour, is then 5000r/min in centrifugal rotational speed, and filter screen is centrifugal filtration under the conditions of 500 purposes, respectively Filter residue and filtrate, filtrate it will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 240kg, refluxing extraction 2 times under the conditions of 40 DEG C, first Secondary extraction 3 hours, the 2nd extraction 1 hour, every time in the bar that centrifugal rotational speed is 5000r/min, filter screen is 500 mesh after extraction Centrifugal filtration under part, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 60 DEG C, -0.09MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 70 DEG C, dry 42 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 14
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product lotus 5, the ㎏ of balsam pear flower 5 of cleaning and the clean ㎏ of dry product jerusalem artichoke 40 are weighed respectively, using vibration ultramicro grinding Machine is crushed, and crosses 250 mesh sieves, obtains lotus, balsam pear pollen and jerusalem artichoke powder respectively;
(2)It is placed in after the ㎏ of lotus powder 5, the ㎏ of balsam pear pollen 5 and the ㎏ of jerusalem artichoke powder 40 are mixed in fermentation tank, adds the pure of 500 ㎏ Water, stir, be heated to 40 DEG C of -42 DEG C of heat-insulation soakings 2 hours, obtain slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 8.25kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 4 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, add by candida utili and Pediococcus acidilactici It is 1 by weight:The compound agglomeration 5.5kg of 1 ratio composition, stirs, ferments 11 hours, must ferment under the conditions of 37 DEG C Liquid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 98 DEG C of insulations and extracted within 2.5 hours, then uses 500 mesh with centrifuge Filter screen centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 250kg, is heated to 100 DEG C Boil 1 hour and extracted, be then 5000r/min in centrifugal rotational speed, filter screen is centrifugal filtration under the conditions of 500 purposes, respectively Filter residue and filtrate are obtained, filtrate will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 350kg, refluxing extraction 2 times under the conditions of 45 DEG C, first It is secondary extraction 2.5 hours, the 2nd time extract 1.5 hours, every time extraction after centrifugal rotational speed be 5000r/min, filter screen be 500 mesh Under conditions of centrifugal filtration, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 60 DEG C, -0.07MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 80 DEG C, dry 32 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Embodiment 15
The preparation of food additives with regulation blood glucose effect:
(1)The ㎏ of dry product wormwoodlike motherwort flower 5 of cleaning is weighed respectively, Radix Angelicae Sinensis spends 3 ㎏, the ㎏ of safflower 2 and the clean ㎏ of dry product jerusalem artichoke 50, use Vibration superfine disintegrator is crushed, and crosses 300 mesh sieves, obtains motherwort, Radix Angelicae Sinensis, safflower pollen and jerusalem artichoke powder respectively;
(2)It is placed in fermentation tank, adds after the ㎏ of motherwort powder 5, the ㎏ of Radix Angelicae Sinensis pollen 3, the ㎏ of safflower powder 2 and the ㎏ of jerusalem artichoke powder 50 are mixed 600 ㎏ pure water, stirs, and is heated to 40 DEG C of -42 DEG C of heat-insulation soakings 2 hours, obtains slurry;
(3)The pectase for being 2000g/U by unit of activity is added into slurry, the fungal amylase that unit of activity is 5000U/g With the cellulase by weight 1 that unit of activity is 2000U/g:2:The complex enzyme 13.2kg of 1 ratio composition, in 40 DEG C of constant temperatures Lower enzymolysis 5 hours, then by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, obtains enzymolysis liquid;
(4)By sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 38 DEG C, add by brewer's yeast and streptococcus thermophilus by weight Measure as 1:The compound agglomeration 7.2kg of 1 ratio composition, stirs, is fermented 10 hours under the conditions of 36 DEG C, obtain zymotic fluid;
(5)Stirred 1 time every 2 hours in above-mentioned fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, zymotic fluid is heated to 97 DEG C of insulations and extracted within 2.75 hours, then uses 500 with centrifuge Mesh filter screen centrifugal filtration under the conditions of 5000r/min, collects filtrate, and filter residue enters the pure water that tank adds 300kg, is heated to 100 DEG C boiling 1 hour and to be extracted, be then 5000r/min in centrifugal rotational speed, filter screen is centrifugal filtration under the conditions of 500 purposes, point Filter residue and filtrate are not obtained, filtrate will merge to obtain aqueous extract twice;
(7)To step(6)Filter residue in content be 60%V/V ethanol 480kg, refluxing extraction 2 times under the conditions of 50 DEG C, first It is secondary extraction 2.5 hours, the 2nd time extract 1.5 hours, every time extraction after centrifugal rotational speed be 5000r/min, filter screen be 500 mesh Under conditions of centrifugal filtration, collect 2 filtrates and merge, obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate, using rotary evaporation inspissator, under the conditions of 65 DEG C, -0.08MPa, it is concentrated into thick Paste;
(11)By step(10)Gained plaster material, using hot-air oven under the conditions of 75 DEG C, dry 37 hours, obtain siccative;
(12)By step(1)Gained siccative is cooled to room temperature, after being crushed with Universalpulverizer, crosses 100 mesh sieves, produces with regulation The food additive powder of blood glucose.
Application Example
Using food additives of the present invention, by weight percentage 3-9% addition, addition is applied in varieties of food items, such as base Plinth food steamed bun, steamed twisted roll, steamed stuffed bun, noodles, won ton, the addition for toasting cake such as bread, biscuit, Layer cake, moon cake, style snacks Agent, 3-9 addition, addition it can also be applied to the sausage or ham of all kinds of meat fillingss and meat packing by weight percentage Intestines, sandwich etc.;3-9 addition, addition it can also be applied to wine product such as white wine, grape wine, beer by weight percentage And yellow rice wine, can also 3-9% addition by weight, addition be applied to seasoning, as baste, soy sauce, vinegar, mayonnaise, Thick chilli sauce, chafing dish bottom flavorings etc.;It is also used as in nutriment such as tablet, capsule, soft capsule, oral liquid formulation.
The preparation of the baste of Application Example 1
Produced using traditional production of condiments method
The additive 5% that Example 1 obtains, fermented sauce 35%, rice vinegar 25%, sesame oil 25%, green onion end 5%, bruised ginger 5%.
The production method of the blended soy sauce of Application Example 2,
The additive 9kg that Example 1 obtains, add in existing soy sauce 91kg, stir, be then put in 5 DEG C of environment ageings 1 Zhou Hou, filtering, which dispenses, to be produced.
The production method of the preparation of vinegar of Application Example 3
The additive 5kg that Example 2 obtains, existing vinegar 95kg is added, is stirred, be then put under 5 DEG C of environment and be aged 1 Zhou Hou, filtering, which dispenses, to be produced.
The preparation of the soft capsule of Application Example 4
Produced with following raw materials according by the production method of in general soft capsule
The additive 25mg that Example 3 obtains, safflower oil 75mg, walnut oil 100mg, tea oil 100mg.
The formula of the hot and numb flavour seasoning of Application Example 5
Produced by traditional production of condiments method
The additive 8% that Example 2 obtains, garlic solvent 8%, spicy hot noodles 4%, chilli powder 15%, vegetable oil 65%.
The present invention has the food additives of regulation blood glucose effect, by its weight ratio requirement with major ingredient 3-9%, Neng Goushi Existing all various products as described in the present invention, its application is only limited by adding proportion, not by the citing of use above embodiment Limitation, it is the conventional method production by the specific product of in general due to preparing in product process for addition additive of the present invention, The product thus just prepared differs a citing, but this has no effect on protection scope of the present invention.

Claims (13)

1. a kind of food additives with regulation blood glucose effect, use dry product plants and flowers, jerusalem artichoke as raw material, by plant flowers Grass, jerusalem artichoke 1:3-5 part by weight, is made up of following methods:
(1)The dry product plants and flowers and clean dry product jerusalem artichoke for weighing cleaning respectively are crushed, and cross 200-300 mesh sieves, respectively Plants and flowers powder and jerusalem artichoke powder;
(2)Inserted after plants and flowers powder, jerusalem artichoke powder are mixed in proportion in fermentation tank, add the pure water of 10 times of weight of raw material, Stir, be heated to 40 DEG C of -42 DEG C of heat-insulation soakings two hours, obtain slurry;
(3)To step(2)Weight is added in slurry than the complex enzyme for 1-2%, 3-5 hours are digested under 40 DEG C of constant temperatures, so Afterwards by feed liquid is heated to 95 DEG C, 10min is sterilized and enzyme deactivation, enzymolysis liquid is obtained;
(4)By step(3)Sterilizing and enzymolysis solution after enzyme deactivation, when being allowed to cool to 37 DEG C, it is 10-12% to add raw material weight ratio Compound agglomeration, under the conditions of 36 DEG C -38 DEG C ferment 10-12 hours, obtain zymotic fluid;
(5)Stirred 1 time every two hours in fermentation process, mixing time is 5-7 minutes;
(6)After fermentation ends, by zymotic fluid be heated to 95-98 DEG C insulation 2.5-3 hours extracted, be then in centrifugal rotational speed 5000r/min, filter screen are centrifugal filtration under the conditions of 500 purposes, collect filtrate, and filter residue enters tank, adds the pure of 5 times of raw material weight Water, it is heated to 100 DEG C and boils 1 hour to re-start extraction, is then 5000r/min in centrifugal rotational speed, filter screen is 500 condition Lower centrifugal filtration obtains filter residue and filtrate respectively, filtrate will merge twice, and obtain aqueous extract;
(7)To step(6)Filter residue in, the ethanol that raw material 6-8 times of weight content is 60%V/V is added, under the conditions of 40-50 DEG C Refluxing extraction twice, is extracted 2-3 hours for the first time, second of extraction 1-1.5 hour, is in centrifugal rotational speed after extraction every time 5000r/min, filter screen are centrifugal filtration under the conditions of 500 purposes, collect filtrate twice, merge to obtain ethanol extract;
(8)By step(7)Ethanol extract reclaims ethanol, obtains concentrate;
(9)By step(8)Gained concentrate is added to step(6)In gained aqueous extract, it is thoroughly mixed uniformly, uses diatom Native filter, filtered under filter pressure 0.2MPa, obtain filtrate;
(10)By step(9)Obtained filtrate is concentrated into paste under the conditions of 50-80 DEG C, -0.065MPa~-0.1MPa;
(11)By step(10)Gained plaster material, under the conditions of 50 DEG C -90 DEG C, 32-42 hours are dried, obtain siccative;
(12)By step(11)Gained siccative is cooled to room temperature, crushed, and the material after crushing crosses 100 mesh sieves, obtains powdered food Product additive.
2. the food additives with regulation blood glucose effect as claimed in claim 1, it is characterised in that described dry product plant Flowers be white twigs of the chaste tree flower, citrus flower, Flores tiliae, lychee flower, sesame flower, cotton, Chinese tallow tree, by set flower, water banyan, nightshade, Firecracker flower, butterflybush flower, magnolia(Flower bud), poplar Chinese holly flower(Male inflorescence), ponceau, oyster plant inflorescence, west Szechwan pyrethrum flower flower, flos longan, lily, Honeysuckle, chrysanthemum, chrysanthemum indicum, snow chrysanthemum, marigold, flower of kudzuvine, sophora flower, Pagoda Flower, jujube flower, russianolive flower, ginkgo, peach blossom, apricot flower, Rose, gardenia, Jasmine, Flos Hibisci Mutabilis, sweet osmanthus, safflower, hops, betelnutpalm male flower, shrub althea flower, yulan magnolia, lotus, pomegranate Flower, sanchi flower, salvia miltiorrhiza flower, China rose, azalea, bitter tattooing, Panzhihua flower, plum blossom, dahurian rose flower, pink, forget-me-not are colored, smoke The clothing showy flowers of herbaceous plants, camellia, lilac, peony, strawberry, Radix Isatidis flower, rape flower, Flos Forsythiae, Chinese aloe flower, multiple hedgehogcactus flower, Radix Angelicae Sinensis Flower, platycodon flower, beggar's buttons, Ligusticum wallichii flower, Chinese ilex, Chinese magnoliavine flower, pumpkin flower, radix glycyrrhizae, Snakegourd Fruit flower, mustard, Zijin lotus flower, Ulex flower, Chinese photinia flower, Chinese flowering crabapple, bodhi, ditch wintercherry flower, anthemidis flos, peppermint flower, Flos Albiziae, peony, gillyflower, Rosemary flower, Roselle, SEMEN OROXYLI flower, globe amaranth, the lemon showy flowers of herbaceous plants, Agrimony flower, balsamine, Flos clematidis floridae, pot marigold, dragon The courage showy flowers of herbaceous plants, cyani flos, pear flower, sponge gourd flower, rose, flower of hyacinth dolichos, pine tree, pea flowers, flower of Panax ginseng, showy flowers of herbaceous plants tomorrow, caulis bambusae in taenian Flower, fleeceflower flower, gynostemma pentaphylla, barrenwort flower, eclipta, the accumulated snow showy flowers of herbaceous plants, sealwort flower, Bank's rose, shell of seaear flower, arbor-vitae Flower, American lotus, wormwoodlike motherwort flower, Chinese mosla flower, SEMEN SINAPIS ALBAE flower, cordate houttuynia, balm flower, witloof, Chinese torreyanut flower, mulberry tree, purple perilla Flower, Jiang Hua, Buckwheat Flower, sunflower, small thistle, red paeony flower, punching lotus flower, Chinese violet, dandelion, Flos Lycii, mountain Short, bristly hair or beard flower, dark plum flower, cablin patchouli flower, sea-buckthorn, Flos Semen Lablab Album, radix scrophulariae flower, Flos Magnoliae Officinalis, cymose buckwheat rhizome flower, Astragalis flower, Echinacea flower, lose The sauce showy flowers of herbaceous plants, a string of safflowers, cockscomb, oriental cherry, cherry blossom, balsam pear flower, jerusalem artichoke flower, orchid, Flos Mume, kamuning flower, canna Flower, Flos Hibisci Rosae-Sinensis, tree orchid, spearmint, fringed iris, Chinese lute flower, Flos Magnoliae Liliflorae, finger citron flower, Michelia figo, common rush, pith are colored, glutinous Meter Xiang Hua, wooden red bayberry, tawny daylily, white dead nettle, popcorn, lehua, broom top, tussilago, ivy glorybind, big thistle, Tulip, honeysuckle, frost flower, by chrysanthemum, by the showy flowers of herbaceous plants, small beautiful flower, okra, chu lan flower, bitter citrus immature flower, oriental wormwood, Any of the above combination of one or both of sweetleaf chrysanthemum, flower of JINHUAKUI, raspberry flower, stem of noble dendrobium flower, blueberry flower, Siberian elm leaf plum blossom.
3. the food additives with regulation blood glucose effect as claimed in claim 1, it is characterised in that the step(1)Institute The crushing stated is ultramicro grinding;It is preferred that use vibration superfine disintegrator.
4. the food additives with regulation blood glucose effect as claimed in claim 1, it is characterised in that the step(3)Institute The complex enzyme stated, for be 2000u/g by unit of activity pectase, unit of activity be 5000u/g fungal amylase and vigor The cellulase that unit is 2000u/g is 1 by weight:2:1 ratio compound forms.
5. the food additives with regulation blood glucose effect as claimed in claim 1, it is characterised in that the step(3)Institute The compound agglomeration stated is by weight being 1 by saccharomycete and lactic acid bacteria:1 proportions form.
6. the food additives with regulation blood glucose effect as claimed in claim 5, it is characterised in that described saccharomycete is Any one viable bacteria in commercially available edible brewer's yeast, brewer's yeast, candida tropicalis, candida utili and Saccharomyces cerevisiae Dry powder product.
7. the food additives with regulation blood glucose effect as claimed in claim 5, it is characterised in that described lactic acid bacteria is Commercially available edible lactobacillus acidophilus, lactobacillus thermophilus, lactobacillus bulgaricus, Bifidobacterium, streptococcus thermophilus and lactic acid sheet ball Any one viable bacteria dry powder product in bacterium.
8. the food additives with regulation blood glucose effect as claimed in claim 1, it is characterised in that the step(9)Institute The concentration stated is using vacuum rotary evaporator, tubular type evaporation concentrator or pulls formula evaporation concentrator;Preferable concentration condition is 60 DEG C -70 DEG C, -0.07MPa~-0.09MPa.
9. the food additives with regulation blood glucose effect as claimed in claim 1, it is characterised in that the step(10)Institute The drying stated uses heated-air drying, far-infrared ray drying or microwave drying;Preferable drying condition is to be done under the conditions of 70 DEG C -80 DEG C Dry 38-42 hours.
A kind of 10. application of food additives that there is regulation blood glucose to act on according to claim 1, by 3%-9% weight The addition of percentage, the application in varieties of food items.
A kind of 11. application of food additives that there is regulation blood glucose to act on according to claim 1, by 3%-9% weight The addition of percentage, the application in wine product.
A kind of 12. application of food additives that there is regulation blood glucose to act on according to claim 1, by 3%-9% weight The addition of percentage, the application in seasoning.
A kind of 13. application of food additives that there is regulation blood glucose to act on according to claim 1, by 3%-9% weight The addition of percentage, the application in nutriment product.
CN201711040034.3A 2017-10-31 2017-10-31 A kind of food additives with regulation blood glucose effect and application Withdrawn CN107668715A (en)

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