CN107646885A - A kind of sterilized eliminating smell agent and preparation method thereof - Google Patents
A kind of sterilized eliminating smell agent and preparation method thereof Download PDFInfo
- Publication number
- CN107646885A CN107646885A CN201710665905.4A CN201710665905A CN107646885A CN 107646885 A CN107646885 A CN 107646885A CN 201710665905 A CN201710665905 A CN 201710665905A CN 107646885 A CN107646885 A CN 107646885A
- Authority
- CN
- China
- Prior art keywords
- parts
- sterilized
- tertiary amine
- eliminating smell
- medical stone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title claims description 50
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 135
- 239000004575 stone Substances 0.000 claims abstract description 93
- 239000000284 extract Substances 0.000 claims abstract description 90
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 82
- 239000000419 plant extract Substances 0.000 claims abstract description 61
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 58
- 239000000843 powder Substances 0.000 claims abstract description 50
- 229920002379 silicone rubber Polymers 0.000 claims abstract description 50
- 240000001432 Calendula officinalis Species 0.000 claims abstract description 39
- 235000005881 Calendula officinalis Nutrition 0.000 claims abstract description 39
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 36
- 239000008367 deionised water Substances 0.000 claims abstract description 30
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 30
- 239000000377 silicon dioxide Substances 0.000 claims abstract description 29
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims abstract description 26
- 235000009024 Ceanothus sanguineus Nutrition 0.000 claims abstract description 26
- 240000003553 Leptospermum scoparium Species 0.000 claims abstract description 26
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 26
- 229940105902 mint extract Drugs 0.000 claims abstract description 26
- 239000000341 volatile oil Substances 0.000 claims abstract description 26
- KHSLHYAUZSPBIU-UHFFFAOYSA-M benzododecinium bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)CC1=CC=CC=C1 KHSLHYAUZSPBIU-UHFFFAOYSA-M 0.000 claims abstract description 22
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 claims abstract description 17
- 238000011068 loading method Methods 0.000 claims abstract description 10
- -1 dodecyl dimethyl benzene Methyl bromide ammonium Chemical compound 0.000 claims description 89
- 150000003512 tertiary amines Chemical class 0.000 claims description 31
- YWFWDNVOPHGWMX-UHFFFAOYSA-N n,n-dimethyldodecan-1-amine Chemical compound CCCCCCCCCCCCN(C)C YWFWDNVOPHGWMX-UHFFFAOYSA-N 0.000 claims description 30
- 238000003756 stirring Methods 0.000 claims description 19
- LRWZZZWJMFNZIK-UHFFFAOYSA-N 2-chloro-3-methyloxirane Chemical compound CC1OC1Cl LRWZZZWJMFNZIK-UHFFFAOYSA-N 0.000 claims description 18
- 239000002994 raw material Substances 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 7
- 244000246386 Mentha pulegium Species 0.000 claims description 6
- 235000016257 Mentha pulegium Nutrition 0.000 claims description 6
- 235000004357 Mentha x piperita Nutrition 0.000 claims description 6
- 235000001050 hortel pimenta Nutrition 0.000 claims description 6
- 238000010792 warming Methods 0.000 claims description 6
- SNRUBQQJIBEYMU-UHFFFAOYSA-N Dodecane Natural products CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 claims description 5
- 239000002245 particle Substances 0.000 claims description 4
- 150000002460 imidazoles Chemical class 0.000 claims description 2
- BGHCVCJVXZWKCC-UHFFFAOYSA-N tetradecane Chemical compound CCCCCCCCCCCCCC BGHCVCJVXZWKCC-UHFFFAOYSA-N 0.000 claims 2
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims 1
- 235000019441 ethanol Nutrition 0.000 description 41
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 24
- 241000205585 Aquilegia canadensis Species 0.000 description 17
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 17
- 239000007864 aqueous solution Substances 0.000 description 15
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 14
- 230000008859 change Effects 0.000 description 14
- VAOCPAMSLUNLGC-UHFFFAOYSA-N metronidazole Chemical compound CC1=NC=C([N+]([O-])=O)N1CCO VAOCPAMSLUNLGC-UHFFFAOYSA-N 0.000 description 14
- 229960000282 metronidazole Drugs 0.000 description 13
- 239000000243 solution Substances 0.000 description 13
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 12
- 240000002853 Nelumbo nucifera Species 0.000 description 12
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 12
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 12
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 12
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 11
- 229910052737 gold Inorganic materials 0.000 description 11
- 239000010931 gold Substances 0.000 description 11
- 238000000034 method Methods 0.000 description 10
- 230000001954 sterilising effect Effects 0.000 description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 8
- 230000000844 anti-bacterial effect Effects 0.000 description 8
- 239000012043 crude product Substances 0.000 description 8
- 229920000642 polymer Polymers 0.000 description 8
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 description 8
- 229960000583 acetic acid Drugs 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 230000006870 function Effects 0.000 description 7
- 239000012362 glacial acetic acid Substances 0.000 description 7
- 241000894006 Bacteria Species 0.000 description 6
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 6
- 125000001453 quaternary ammonium group Chemical group 0.000 description 6
- 230000003115 biocidal effect Effects 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 5
- 238000001914 filtration Methods 0.000 description 5
- 235000013305 food Nutrition 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 239000000178 monomer Substances 0.000 description 5
- 235000011121 sodium hydroxide Nutrition 0.000 description 5
- 238000004659 sterilization and disinfection Methods 0.000 description 5
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 4
- WBYWAXJHAXSJNI-VOTSOKGWSA-M .beta-Phenylacrylic acid Natural products [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 4
- WBYWAXJHAXSJNI-SREVYHEPSA-N Cinnamic acid Chemical compound OC(=O)\C=C/C1=CC=CC=C1 WBYWAXJHAXSJNI-SREVYHEPSA-N 0.000 description 4
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 4
- 241000191967 Staphylococcus aureus Species 0.000 description 4
- 239000002253 acid Substances 0.000 description 4
- 230000000845 anti-microbial effect Effects 0.000 description 4
- 238000005119 centrifugation Methods 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 229930016911 cinnamic acid Natural products 0.000 description 4
- 235000013985 cinnamic acid Nutrition 0.000 description 4
- 239000012141 concentrate Substances 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 239000012065 filter cake Substances 0.000 description 4
- 235000011187 glycerol Nutrition 0.000 description 4
- 239000001525 mentha piperita l. herb oil Substances 0.000 description 4
- 229940041616 menthol Drugs 0.000 description 4
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 4
- 229920001983 poloxamer Polymers 0.000 description 4
- 229960000502 poloxamer Drugs 0.000 description 4
- 229920001993 poloxamer 188 Polymers 0.000 description 4
- 229940044519 poloxamer 188 Drugs 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 229910052709 silver Inorganic materials 0.000 description 4
- 239000004332 silver Substances 0.000 description 4
- 229910001961 silver nitrate Inorganic materials 0.000 description 4
- 239000001509 sodium citrate Substances 0.000 description 4
- 238000001179 sorption measurement Methods 0.000 description 4
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 4
- 229940038773 trisodium citrate Drugs 0.000 description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 3
- QCNJTOVOGHNLRT-UHFFFAOYSA-N CBr(CCCCCCCCCCCC)(CC1=CC=CC=C1)C Chemical compound CBr(CCCCCCCCCCCC)(CC1=CC=CC=C1)C QCNJTOVOGHNLRT-UHFFFAOYSA-N 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 3
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 238000005260 corrosion Methods 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 235000019477 peppermint oil Nutrition 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 241001287809 Nierembergia Species 0.000 description 2
- 206010036790 Productive cough Diseases 0.000 description 2
- 241000607764 Shigella dysenteriae Species 0.000 description 2
- 240000009022 Smilax rotundifolia Species 0.000 description 2
- 235000003205 Smilax rotundifolia Nutrition 0.000 description 2
- 206010000269 abscess Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 2
- 230000001139 anti-pruritic effect Effects 0.000 description 2
- 239000003908 antipruritic agent Substances 0.000 description 2
- 244000052616 bacterial pathogen Species 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 239000003480 eluent Substances 0.000 description 2
- 238000010828 elution Methods 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 239000011521 glass Substances 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 238000009413 insulation Methods 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 2
- 150000002894 organic compounds Chemical class 0.000 description 2
- 235000020737 peppermint extract Nutrition 0.000 description 2
- 238000011056 performance test Methods 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 229940007046 shigella dysenteriae Drugs 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M sodium bicarbonate Substances [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 239000008279 sol Substances 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 208000024794 sputum Diseases 0.000 description 2
- 210000003802 sputum Anatomy 0.000 description 2
- 238000013268 sustained release Methods 0.000 description 2
- 239000012730 sustained-release form Substances 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 229920001897 terpolymer Polymers 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 241000712461 unidentified influenza virus Species 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 244000237138 Asphodeline lutea Species 0.000 description 1
- 235000000458 Asphodeline lutea Nutrition 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- NAIKCHJVANAEKA-UHFFFAOYSA-N C(C)ON1C(=NC=C1[N+](=O)[O-])C Chemical class C(C)ON1C(=NC=C1[N+](=O)[O-])C NAIKCHJVANAEKA-UHFFFAOYSA-N 0.000 description 1
- 241000345998 Calamus manan Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 235000007516 Chrysanthemum Nutrition 0.000 description 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 description 1
- 241001672694 Citrus reticulata Species 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241001131815 Egretta garzetta Species 0.000 description 1
- 241000305071 Enterobacterales Species 0.000 description 1
- 239000004593 Epoxy Substances 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 240000007707 Mentha arvensis Species 0.000 description 1
- 235000018978 Mentha arvensis Nutrition 0.000 description 1
- 244000061176 Nicotiana tabacum Species 0.000 description 1
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 240000006322 Sambucus chinensis Species 0.000 description 1
- 235000010426 Sambucus chinensis Nutrition 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 241000593989 Scardinius erythrophthalmus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- 241000654871 Triunia youngiana Species 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000024780 Urticaria Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000001754 anti-pyretic effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000002155 anti-virotic effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 208000002399 aphthous stomatitis Diseases 0.000 description 1
- 210000004666 bacterial spore Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 235000020965 cold beverage Nutrition 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000004035 construction material Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000006837 decompression Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000001877 deodorizing effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 235000012950 rattan cane Nutrition 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000010583 slow cooling Methods 0.000 description 1
- 239000010802 sludge Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000001256 steam distillation Methods 0.000 description 1
- 239000003206 sterilizing agent Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 235000014101 wine Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/16—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/22—Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
- A61L9/013—Deodorant compositions containing animal or plant extracts, or vegetable material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
- A61L9/014—Deodorant compositions containing sorbent material, e.g. activated carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/20—Method-related aspects
- A61L2209/21—Use of chemical compounds for treating air or the like
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Agronomy & Crop Science (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Inorganic Chemistry (AREA)
- Toxicology (AREA)
- Botany (AREA)
- Materials Engineering (AREA)
- Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention provides a kind of sterilized eliminating smell agent, it is characterised in that calculates by weight, the sterilized eliminating smell agent includes：Modified 30 50 parts of medical stone, 5 13 parts of modified silicon rubber powder, 2 15 parts of plant extracts, 0.5 3 parts of neopelex, 0.5 2 parts of tea tree ethereal oil, 30 60 parts of deionized water, 0.1 5 parts of lauric monoglyceride, 0.5 2 parts of dodecyl dimethyl benzyl ammonium bromide, 30 55 parts of ethanol；Wherein, the plant extracts includes mint extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is that nano medical stone is grafted bi-quaternary ammonium salt, and the modified silicon rubber powder is the silica white loading nano silvery, and the ethanol is the ethanol water that mass fraction is 60%.
Description
Technical field
The present invention relates to family's product technique field, in particular it relates to a kind of sterilized eliminating smell agent and its system
Preparation Method.
Background technology
In people in life, more than 80% time is spent indoors.Infant, the old,weak,sick and disabled crowd stop indoors
The time stayed is longer.Food necessary to air is the mankind.Indoor air quality monitoring is reported according to Chinese Medical Association's organizes expert
Show, in various public places, by influenza, respiratory passage infectious disease patients, the sputum for the patient that carries disease germs, cough, spray
Sneeze a variety of germs such as the influenza virus, tubercle bacillus, streptococcus of pollution spread, the phenomenon it occur frequently that group is caught an illness, to family
Life and social activities bring more troubles, have a strong impact on the health of people.
At present, in refrigerator, refrigerator-freezer, the meat safe in shop or toilet, reception room, office, automobile, often place
Stink-removing sterilizer, wherein being typically all placed with activated carbon deodorizing and sterilizing agent, it adsorbs the material for removing and having peculiar smell from air, and has
Sterilizing ability.But its adsorption efficiency is low, sterilization capability is not strong and by such environmental effects.
Therefore, in view of the above-mentioned problems, the present invention provides a kind of sterilized eliminating smell agent, its can kill Staphylococcus aureus,
Escherichia coli, pseudomonas aeruginosa, shigella dysenteriae and white read the various bacterias such as coccobacillus, and adsorption capacity and sterilization capability are excellent,
Sterilization sterilizing, anti-corrosion with high intensity, fresh-keeping and function of odor removal；Sterilized eliminating smell agent provided by the invention it is also sprayable in
The surface of various containers, prevents microbial growth in glass, ceramic utensil, construction material, plastic products and food industry.
The content of the invention
In order to solve the above problems, first aspect present invention provides a kind of sterilized eliminating smell agent, by weight
Calculate, the sterilized eliminating smell agent includes：Modified medical stone 30-50 parts, modified silicon rubber powder 5-13 parts, plant extracts 2-15
Part, neopelex 0.5-3 parts, tea tree ethereal oil 0.5-2 parts, deionized water 30-60 parts, lauric monoglyceride
0.1-5 parts, dodecyl dimethyl benzyl ammonium bromide 0.5-2 parts, ethanol 30-55 parts；
Wherein, the plant extracts includes mint extract, pot marigold extract, orange peel extract, honeysuckle extraction
Thing；The modified medical stone is that nano medical stone is grafted bi-quaternary ammonium salt, and the modified silicon rubber powder is that the silica white loads nanometer
Silver, the ethanol are the ethanol water that mass fraction is 60%.
In one embodiment, calculate by weight, the sterilized eliminating smell agent includes：Modified medical stone 35-45
Part, modified silicon rubber powder 8-12 parts, plant extracts 2-10 parts, neopelex 0.5-2 parts, tea tree ethereal oil 0.5-2 parts, go
Ionized water 40-50 parts, lauric monoglyceride 1-5 parts, dodecyl dimethyl benzyl ammonium bromide 0.5-2 parts, ethanol 40-55 parts.
In one embodiment, calculate by weight, the sterilized eliminating smell agent includes：Modified 42 parts of medical stone,
9 parts of modified silicon rubber powder, 10 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, deionized water 46 part, month
2 parts of cinnamic acid monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol.
In one embodiment, mint extract described in the plant extracts and the pot marigold extract, institute
State orange peel extract, the weight ratio of the Honegsukle flower P.E is 1：(0.5-1)：(1-6)：(2-5).
In one embodiment, mint extract described in the plant extracts and the pot marigold extract, institute
State orange peel extract, the weight ratio of the Honegsukle flower P.E is 1：0.8：4：3.
In one embodiment, bi-quaternary ammonium salt described in the modified medical stone is bi-quaternary ammonium salt containing imidazolyl heterocycle, institute
Stating the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle includes metronidazole, epoxychloropropane, long-chain
Alkyl tertiary amine.
In one embodiment, the long-chain alkyl tertiary amine includes Dodecyl Dimethyl Amine, dodecyldimethylamine
One or more in base tertiary amine, hexadecyldimethyl benzyl ammonium tertiary amine, dodecylbenzyl methyl tertiary amine.
In one embodiment, the long-chain alkyl tertiary amine is dodecyldimethylamine base tertiary amine, dodecylbenzyl first
Base tertiary amine.
In one embodiment, dodecyldimethylamine base tertiary amine described in the long-chain alkyl tertiary amine and the dodecane
The weight ratio of base benzyl methyl tertiary amine is 1：(0.1-0.6).
Another aspect of the present invention provides a kind of preparation method of sterilized eliminating smell agent, comprises the following steps：
(1) modified silicon rubber powder, neopelex are added by weight into reactor, lauric monoglyceride,
Stir, 1h is stirred after being warming up to 40-50 DEG C, 50 DEG C are dried under reduced pressure 8h；
(2) modified medical stone, deionized water, dodecyl dimethyl benzyl bromine are added in mixture into step (1)
Change ammonium, dried after stirring；
(3) it is 60% tea tree ethereal oil, plant extracts and mass fraction to be added in the particle dried into step (2)
Ethanol water, is stirred well mixed, obtains the sterilized eliminating smell agent.
The above-mentioned of the application and other features, aspect and advantage is more readily understood with reference to described further below.
Embodiment
Participate in the election of the detailed description of the invention below for being preferable to carry out method and including embodiment this hair can be more easily understood
Bright content.Unless otherwise defined, all technologies used herein and scientific terminology have common with art of the present invention
The identical implication that technical staff is generally understood that.When contradiction be present, the definition in this specification is defined.
As used herein term " by ... prepare " it is synonymous with "comprising".Term "comprising" used herein, " comprising ",
" having ", " containing " or its any other deformation, it is intended that cover including for non-exclusionism.For example, the combination comprising listed elements
Thing, step, method, product or device are not necessarily limited to those key elements, but can include not expressly listed other key elements or
Such a composition, step, method, product or the intrinsic key element of device.
Conjunction " Consists of " excludes any key element do not pointed out, step or component.If be used in claim, this
Phrase will make claim be closed, it is not included the material in addition to the material of those descriptions, but relative normal
Except rule impurity.When being rather than immediately following in the clause that phrase " Consists of " appears in claim main body after theme,
It is only limited to the key element described in the clause；Other key elements are not excluded outside the claim as entirety.
Equivalent, concentration or other values or parameter are excellent with scope, preferred scope or a series of upper limit preferred values and lower limit
During the Range Representation that choosing value limits, this, which is appreciated that, specifically discloses by any range limit or preferred value and any scope
All scopes that any pairing of lower limit or preferred value is formed, regardless of whether the scope separately discloses.For example, when open
During scope " 1 to 5 ", described scope should be interpreted as including scope " 1 to 4 ", " 1 to 3 ", " 1 to 2 ", " 1 to 2 and 4 to
5 ", " 1 to 3 and 5 " etc..When number range is described herein, unless otherwise indicated, otherwise the scope is intended to include its end
Value and all integers and fraction within the range.
Singulative includes plural number and object is discussed, unless the context clearly dictates otherwise." optional " or it is " any
It is a kind of " refer to that the item that describes thereafter or event may or may not occur, and the description include situation that event occurs and
The situation that event does not occur.
Approximate term in specification and claims is used for modifying quantity, and it is specific to represent that the present invention is not limited to this
Quantity, include the part of the amendment of the acceptable change without cause related basic function close to the quantity.Phase
Answer, modify a numerical value with " about ", " about " etc., mean that the invention is not restricted to the exact numerical.It is approximate in some examples
Term likely corresponds to the precision of the instrument of measured value.In present specification and claims, scope limits can be with
Combine and/or exchange, these scopes include all subranges contained therebetween if not stated otherwise.
In addition, indefinite article " one kind " before key element of the present invention or component and "one" to key element or the quantitative requirement of component
(i.e. occurrence number) unrestriction.Therefore "one" or " one kind " should be read as including one or at least one, and odd number
The key element or component of form also include plural form, unless the obvious purport of the quantity refers to singulative.
" polymer " means by the polymerizable compound prepared by the monomer that polymerize identical or different type.Generic term
" polymer " includes term " homopolymer ", " copolymer ", " terpolymer " and " EVA ".
" EVA " means the polymer prepared by polymerizeing at least two different monomers.Generic term " EVA " includes
(its is general with term " terpolymer " for term " copolymer " (its typically to refer to the polymer prepared by two kinds of different monomers)
To refer to the polymer prepared by three kinds of different monomers).It is also included by polymerizeing more kinds of monomers the polymer that manufactures.
" blend " means that two or more polymer mixes the polymer to be formed by physics or chemical method jointly.
First aspect present invention provides a kind of sterilized eliminating smell agent, calculates by weight, described sterilized to remove
Taste agent includes：Modified medical stone 30-50 parts, modified silicon rubber powder 5-13 parts, plant extracts 2-15 parts, neopelex
0.5-3 parts, tea tree ethereal oil 0.5-2 parts, deionized water 30-60 parts, lauric monoglyceride 0.1-5 parts, dodecyl dimethyl
Benzyl ammonium bromide 0.5-2 parts, ethanol 30-55 parts；
Wherein, the plant extracts includes mint extract, pot marigold extract, orange peel extract, honeysuckle extraction
Thing；The modified medical stone is that nano medical stone is grafted bi-quaternary ammonium salt, and the modified silicon rubber powder is that the silica white loads nanometer
Silver, the ethanol are the ethanol water that mass fraction is 60%.
In one embodiment, calculate by weight, the sterilized eliminating smell agent includes：Modified medical stone 35-45
Part, modified silicon rubber powder 8-12 parts, plant extracts 2-10 parts, neopelex 0.5-2 parts, tea tree ethereal oil 0.5-2
Part, deionized water 40-50 parts, lauric monoglyceride 1-5 parts, dodecyl dimethyl benzyl ammonium bromide 0.5-2 parts, ethanol
40-55 parts.
In one embodiment, calculate by weight, the sterilized eliminating smell agent includes：Modified 42 parts of medical stone,
9 parts of modified silicon rubber powder, 10 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, deionized water 46 part, month
2 parts of cinnamic acid monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol.
In one embodiment, mint extract described in the plant extracts and the pot marigold extract, institute
State orange peel extract, the weight ratio of the Honegsukle flower P.E is 1：(0.5-1)：(1-6)：(2-5).
In one embodiment, mint extract described in the plant extracts and the pot marigold extract, institute
State orange peel extract, the weight ratio of the Honegsukle flower P.E is 1：0.8：4：3.
Mint extract
Peppermint alias be thin severe, greenbrier Lin, Wu's greenbrier Lin, southern peppermint, thin severe, the rising Yang dish of cat, thin Ke, Bo lotus, night breath flower,
It is thin severe, night breath medicine of the Bo lotus of thin severe, Wu's the Bo lotus of thin severe, wild mint, rising Yang dish, Ren Dancao, JIANZHONGXIAO, the beneficial mother of water, Sambucus thunbergiana, native peppermint, with sweet and sour flavor
Grass, herba elsholtziae；Efficacy effect：Dispelling wind, radiating, ward off dirty, removing toxic substances.Affection of exogenous wind-heat is controlled, is had a headache, hot eyes, abscess of throat, food stagnation gas
It is swollen, aphtha, toothache, sore scabies, urticaria；Menthol and peppermint oil dementholized have special fragrant, pungent sense and cool feeling, are mainly used in tooth
Cream, food, tobacco, wine, cold drink, cosmetics, the perfuming of perfumed soap；Wind dispelling, anti-corrosion, anti-inflammatory, town are widely used in medicine
In the medicines such as bitterly, antipruritic, stomach invigorating.All herbal medicine, it is pungent, it is cool.Return lung, Liver Channel, there is diverging wind-heat, clearing throat, promoting eruption removing toxic substances, dredge
Liver solution is strongly fragrant and antipruritic and other effects, suitable for cold, fever, headache, abscess of throat, lossless, wind-fire red eye, rubella, skin itch,
The diseases such as colic, diarrhea and scrofula, external application have slight analgesic effect, for neuralgia etc..
The extracting method of mint extract：Peppermint (herb) that will be clean is added in reactor, add 12 times of quality go from
Sub- water, steam distillation 10h is carried out, obtains peppermint oil crude product；Peppermint oil crude product is freezed into 12h under the conditions of -10 DEG C, obtained thin
Lotus oil and menthol crude product 1；Then water will be distilled off under peppermint oil normal temperature, 24h is freezed under the conditions of -20 DEG C, is obtained thin
Lotus alcohol crude product 2, merge menthol crude product 1 and menthol crude product 2, heating melting, slow cooling is protected to 0 DEG C after complete melting
Warm 2h, filtering, 40 DEG C are dried under reduced pressure, and obtain mint extract.
Pot marigold extract
Pot marigold alias is pot marigold, gold small cup, long-living chrysanthemum, flower of sobering up, asphodel, golden small cup etc.；Pot marigold nature and flavor are light flat,
Flower, leaf have anti-inflammatory, antibacterial action.The root energy promoting flow of qi and blood circulation, flower can cool blood, hemostasis.Europe it is among the people it is outer for skin, mucous membrane it is various
Inflammation, can also the various inflammation of orally taken for curing and ulcer.
The extracting method of pot marigold extract：The n-hexane that 10 times of weight is added into the pot marigold of cleaning carries out closed surpass
Sound extracts, and condition is：0.1-10MPa, time 6h, temperature is at 60 DEG C, and after filtering, extract is concentrated under reduced pressure, and carries out low temperature and does
It is dry, obtain pot marigold extract.
Orange peel extract
Orange peel alias is orange peel, expensive old, red skin, yellow orange peel, wide orange peel, PERICARPIUM CITRI RETICULATAE, orange peel, citrus chachiensis hortorum.Efficacy effect：Reason
Gas invigorating the spleen, it is eliminating dampness and eliminating phlegm.Vomited and diarrhoea for deficiency of food, coughing with a lot of sputum.
The extracting method of orange peel extract：The deionized water that 10 times of weight is added into dry orange peel decoct 2 times,
Then decocting liquid is concentrated under reduced pressure into dry, obtains concentrate, by concentrate by polyamide column, successively with deionized water, quality point
Count the ethanol water punching that the ethanol water for 10%, the ethanol water that mass fraction is 25%, mass fraction are 35%
After washing, then eluted with the ethanol water that mass fraction is 50%, collect eluent, the eluent that is concentrated under reduced pressure is to Dalai's energy
Enough solids separate out, filtering, elute filter cake with absolute ethyl alcohol, obtain orange peel extract.
Honegsukle flower P.E
Honeysuckle alias honeysuckle flower, honeysuckle, two flowers, two precious flowers, honeysuckle flowers, little egret flower, Su Hua, golden flower, golden rattan, double buds
Flower, mountain gold honeysuckle flower, native honeysuckle, wild honeysuckle；Efficacy effect：It is clearing heat and detoxicating, main warm disease heating；Toxic-heat and blood stasis；Carbuncle swells furunculosis；Larynx numbness
And multi-infection disease；The effects such as honeysuckle has antibacterial, antiviral, anti-inflammatory, antipyretic, regulation is immune.
The extracting method of Honegsukle flower P.E：The deionized water of honeysuckle, 10 times of weight is subjected to decocting and boils 2 times, then
Decocting liquid is concentrated under reduced pressure into the 1/3 of decocting liquid original volume, be slowly added to mass fraction be 20% aqua calcis, regulation pH to
10, filtering, absolute ethyl alcohol is added into filter cake, stirred, the sulphur acid for adjusting pH that dropwise addition mass fraction is 50% to 3, stir 0.5h,
Filtering, the pH to 6 of filtrate is adjusted with 1mol/L sodium hydroxide solution, is concentrated under reduced pressure, obtains concentrate；3 are added into concentrate
The deionized water of times weight, extracted, depressurized to 2, then with ethyl acetate with 1mol/L salt acid for adjusting pH after stirring
Ethyl acetate layer is concentrated, ether is added and is stirred 2h, filter, 40 DEG C are dried under reduced pressure 10h, obtain Honegsukle flower P.E.
In one embodiment, bi-quaternary ammonium salt described in the modified medical stone is bi-quaternary ammonium salt containing imidazolyl heterocycle, institute
Stating the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle includes metronidazole, epoxychloropropane, long-chain
Alkyl tertiary amine.
In one embodiment, the long-chain alkyl tertiary amine includes Dodecyl Dimethyl Amine, dodecyldimethylamine
One or more in base tertiary amine, hexadecyldimethyl benzyl ammonium tertiary amine, dodecylbenzyl methyl tertiary amine.
In one embodiment, the long-chain alkyl tertiary amine is dodecyldimethylamine base tertiary amine, dodecylbenzyl first
Base tertiary amine.
In one embodiment, dodecyldimethylamine base tertiary amine described in the long-chain alkyl tertiary amine and the dodecane
The weight ratio of base benzyl methyl tertiary amine is 1：(0.1-0.6)；Preferably, dodecyldimethylamine described in the long-chain alkyl tertiary amine
The weight ratio of base tertiary amine and the dodecylbenzyl methyl tertiary amine is 1：0.24.
The preparation method of the bi-quaternary ammonium salt containing imidazolyl heterocycle comprises the following steps：
Epoxychloropropane is added to reactor, 75 DEG C is warming up to, long-chain alkyl tertiary amine is slowly added dropwise, after being added dropwise, stir
0.5h is mixed, is cooled to 55 DEG C, adds acetonitrile, then divides 3 addition 1- ethoxy -2- methyl -5- nitroimidazoles, insulation reaction
8h, room temperature is cooled to, be concentrated under reduced pressure, obtain the crude product of bi-quaternary ammonium salt containing imidazolyl heterocycle, added acetone stirring 0.5h, be concentrated under reduced pressure, obtain
Bi-quaternary ammonium salt containing imidazolyl heterocycle；The epoxychloropropane and the long-chain alkyl tertiary amine, the 1- ethoxys -2- methyl -5- nitre
The mol ratio of base imidazoles is 1：0.56：0.6；The weight ratio of the epoxychloropropane and the acetonitrile, the acetone is 1：6：4.
The preparation method of the modified medical stone comprises the following steps：
Nano medical stone, acetone are added into reactor, after stirring, adds 2mol/L sodium hydrate aqueous solution,
Stir, alkalize 3-4h at a temperature of 50 DEG C, the bi-quaternary ammonium salt containing imidazolyl heterocycle of synthesis is then added portionwise, under the conditions of 50-60 DEG C
10h is reacted, after reaction terminates, is cooled to room temperature, filters, filter cake is washed with deionized 3-4 times, again with methanol elution, 40
DEG C 12h is dried under reduced pressure, obtains the modified medical stone；The nano medical stone and the acetone, the sodium hydroxide of the 2mol/L
The aqueous solution, the weight ratio of the bi-quaternary ammonium salt containing imidazolyl heterocycle are 1：5：4：0.4.
Mineral in medical stone all have perfect crystal structure, and its networked pore structures being evenly distributed, surface holes are generally
Open bore, internal holes have interconnected pores, blind hole and semiclosed hole, and the diameter of its hole is about in 10nm or so.Medical stone is to a system
Row organic compound has a certain amount of absorption, and in certain scope medical stone to average molecular matter in organic compound series
That measures small (simple in construction, diameter is small) has stronger adsorptivity；In addition, in the present invention by using active quaternizing agent and
Chain alkyl reacts to form bi-quaternary ammonium salt.Without changing on the basis of metronidazole structure
Its water-soluble and permeability to sticky sludge can be improved, and after introducing nitrogen heterocyclic ring group in bi-quaternary ammonium salt it can be made slow
Release performance to make moderate progress, so except that can change the water solubility of metronidazole, surface-active and kill
Outside bacterium characteristic, moreover it is possible to make new organic diammonium compound that there is stronger sustained release performance, by being grafted on medical stone, enter one
Step improves the sustained release performance and stability of new organic diammonium compound.
Modified medical stone can not only be to the peculiar smell adsorption in air and removal, and also has efficient bactericidal property,
It has the advantages that chemical stability is good, residual toxicity is low, durable antibacterial effect.
The preparation method of the modified silicon rubber powder comprises the following steps：
(1) poloxamer188 is added into silver nitrate aqueous solution, is stirred, adds trisodium citrate, is stirred
Irradiate under ultraviolet light afterwards, obtain Nano Silver stoste；The mass concentration of the silver nitrate aqueous solution is 0.4mg/mL, the nitric acid
The silver-colored weight ratio with the poloxamer188, the trisodium citrate is 1：0.85：0.9；Ice vinegar is added into Nano Silver stoste
Acid solution (mass fraction of glacial acetic acid is 10% in the glacial acetic acid solution), glycerine, stir, add poloxamer
With silica white, silica white-poloxamer colloidal sol of Nano Silver is obtained, NaHCO is added dropwise3Solution adjusts pH to 6, and standing makes its gel
Change, obtain nano silver antimicrobial gel；The Nano Silver stoste and the glacial acetic acid solution, the glycerine, the poloxamer, institute
The weight ratio for stating silica white is 1：0.06：0.06：1.2：0.02；The NaHCO3The concentration of solution is 1mol/L；
(2) nano silver antimicrobial gel, silica white are added into agitator, 3h is stirred, obtains modified silicon rubber powder, the nanometer
The weight ratio of silver-colored antibacterial gel and the silica white is 1：3.
The granularity of heretofore described silica white is 200-400 mesh；Preferably, the granularity of the silica white is 300 mesh.
Another aspect of the present invention provides a kind of preparation method of sterilized eliminating smell agent, comprises the following steps：
(1) modified silicon rubber powder, neopelex are added by weight into reactor, lauric monoglyceride,
Stir, 1h is stirred after being warming up to 40-50 DEG C, 50 DEG C are dried under reduced pressure 8h；
(2) modified medical stone, deionized water, dodecyl dimethyl benzyl bromine are added in mixture into step (1)
Change ammonium, dried after stirring；
(3) it is 60% tea tree ethereal oil, plant extracts and mass fraction to be added in the particle dried into step (2)
Ethanol water, is stirred well mixed, obtains the sterilized eliminating smell agent.
Containing the Nano Silver and quaternary ammonium salt for being capable of durable antibiotic antivirus composition in the present invention, can have day and night for 365 days
Effect ground suppress various harmful bacterias in in-car and indoor influenza virus, Escherichia coli, staphylococcus aureus and air with
And bacterial spore, prevent its propagation, antibiotic rate is up to more than 99.9%；Using deionized water, natural plant extracts, nanometer
Silver, ethanol etc., malicious chemical analysis is not contained, it is without any side effects to body, without secondary pollution, use safety, ring
Protect；Sterilized eliminating smell agent adhesive force is superpower in the present invention, no matter to clear glass, dark home textile, furniture, wallpaper, coating etc.
Surface can arbitrarily spray, unrestricted.
The present invention is specifically described below by embodiment.It is necessarily pointed out that following examples are only used
In the invention will be further described, it is impossible to be interpreted as limiting the scope of the invention, professional and technical personnel in the field
Some the nonessential modifications and adaptations made according to the content of the invention described above, still fall within protection scope of the present invention.
In addition, if without other explanations, it is raw materials used be all it is commercially available, be purchased from traditional Chinese medicines chemical reagent.
Embodiment 1
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Modified medical stone 42
Part, 9 parts of modified silicon rubber powder, 10 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, 46 parts of deionized water,
2 parts of lauric monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes thin
Lotus extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is grafted for nano medical stone
Bi-quaternary ammonium salt, the modified silicon rubber powder are the silica white loading nano silvery, and the ethanol is the ethanol that mass fraction is 60%
The aqueous solution；Mint extract described in the plant extracts and the pot marigold extract, the orange peel extract, the gold
The weight ratio of honeysuckle flower extract is 1：0.8：4：3；Bi-quaternary ammonium salt described in the modified medical stone is containing the double quaternary ammoniums of imidazolyl heterocycle
Salt, the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle include metronidazole, epoxychloropropane,
Long-chain alkyl tertiary amine；The long-chain alkyl tertiary amine is dodecyldimethylamine base tertiary amine, dodecylbenzyl methyl tertiary amine, the length
The weight ratio of dodecyldimethylamine base tertiary amine described in alkyl group tertiary amine and the dodecylbenzyl methyl tertiary amine is 1：0.24；
The preparation method of the sterilized eliminating smell agent, comprises the following steps：
(1) modified silicon rubber powder, neopelex are added by weight into reactor, lauric monoglyceride,
Stir, 1h is stirred after being warming up to 45 DEG C, 50 DEG C are dried under reduced pressure 8h；
(2) modified medical stone, deionized water, dodecyl dimethyl benzyl bromine are added in mixture into step (1)
Change ammonium, dried after stirring；
(3) it is 60% tea tree ethereal oil, plant extracts and mass fraction to be added in the particle dried into step (2)
Ethanol water, is stirred well mixed, obtains the sterilized eliminating smell agent.
The preparation method of the modified medical stone comprises the following steps：
Nano medical stone, acetone are added into reactor, after stirring, adds 2mol/L sodium hydrate aqueous solution,
Stir, alkalize 3h at a temperature of 50 DEG C, and the bi-quaternary ammonium salt containing imidazolyl heterocycle of synthesis is then added portionwise, is reacted under the conditions of 60 DEG C
10h, after reaction terminates, room temperature is cooled to, filters, filter cake is washed with deionized 3 times, again with methanol elution, 40 DEG C of decompressions
12h is dried, obtains the modified medical stone；The nano medical stone and the acetone, the 2mol/L sodium hydrate aqueous solution,
The weight ratio of the bi-quaternary ammonium salt containing imidazolyl heterocycle is 1：5：4：0.4.
The preparation method of the bi-quaternary ammonium salt containing imidazolyl heterocycle comprises the following steps：
Epoxychloropropane is added to reactor, 75 DEG C is warming up to, dodecyldimethylamine in long-chain alkyl tertiary amine is slowly added dropwise
Base tertiary amine, after being added dropwise, 0.5h is stirred, then dodecylbenzyl methyl tertiary amine is slowly added dropwise, stirred 0.5h, be cooled to 55
DEG C, acetonitrile is added, then divides 3 addition metronidazoles, insulation reaction 8h, is cooled to room temperature, subtracts
Pressure concentration, obtains the crude product of bi-quaternary ammonium salt containing imidazolyl heterocycle, adds acetone stirring 0.5h, is concentrated under reduced pressure, and obtains containing the double quaternary ammoniums of imidazolyl heterocycle
Salt；The mol ratio of the epoxychloropropane and the long-chain alkyl tertiary amine, the metronidazole is
1：0.56：0.6；The weight ratio of the epoxychloropropane and the acetonitrile, the acetone is 1：6：4.
The preparation method of the modified silicon rubber powder comprises the following steps：
(1) poloxamer188 is added into silver nitrate aqueous solution, is stirred, adds trisodium citrate, is stirred
Irradiate under ultraviolet light afterwards, obtain Nano Silver stoste；The mass concentration of the silver nitrate aqueous solution is 0.4mg/mL, the nitre
The silver-colored weight ratio with the poloxamer188, the trisodium citrate of acid is 1：0.85： 0.9；Added into Nano Silver stoste
Glacial acetic acid solution (mass fraction of glacial acetic acid is 10% in the glacial acetic acid solution), glycerine, stir, add pool Lip river
Husky nurse and silica white, silica white-poloxamer colloidal sol of Nano Silver is obtained, NaHCO is added dropwise3Solution adjusts pH to 6, and standing makes it
Gelation, obtain nano silver antimicrobial gel；The Nano Silver stoste and the glacial acetic acid solution, the glycerine, the pool Lip river are husky
Nurse, the weight ratio of the silica white are 1：0.06：0.06：1.2：0.02；The NaHCO3The concentration of solution is 1mol/L；
(2) nano silver antimicrobial gel, silica white are added into agitator, 3h is stirred, obtains modified silicon rubber powder, the nanometer
The weight ratio of silver-colored antibacterial gel and the silica white is 1：3；The granularity of the silica white is 300 mesh.
Embodiment 2
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Modified medical stone 30
Part, 13 parts of modified silicon rubber powder, 15 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, deionized water 49
Part, 2 parts of lauric monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts bag
Include mint extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is nano medical stone
Bi-quaternary ammonium salt is grafted, the modified silicon rubber powder is the silica white loading nano silvery, and the ethanol is that mass fraction is 60%
Ethanol water；Mint extract described in the plant extracts and the pot marigold extract, the orange peel extract, institute
The weight ratio for stating Honegsukle flower P.E is 1：0.8：4：3；Bi-quaternary ammonium salt described in the modified medical stone is double containing imidazolyl heterocycle
Quaternary ammonium salt, the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle include metronidazole, epoxy chloropropionate
Alkane, long-chain alkyl tertiary amine；The long-chain alkyl tertiary amine is dodecyldimethylamine base tertiary amine, dodecylbenzyl methyl tertiary amine, described
The weight ratio of the tertiary amine of dodecyldimethylamine base described in long-chain alkyl tertiary amine and the dodecylbenzyl methyl tertiary amine is 1：0.24；
The preparation method of the sterilized eliminating smell agent, the preparation method of the modified medical stone, described contain imidazolyl heterocycle
The preparation method of bi-quaternary ammonium salt, the preparation method of the modified silicon rubber powder are the same as embodiment 1.
Embodiment 3
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Modified medical stone 50
Part, 5 parts of modified silicon rubber powder, 6 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, 46 parts of deionized water,
2 parts of lauric monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes thin
Lotus extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is grafted for nano medical stone
Bi-quaternary ammonium salt, the modified silicon rubber powder are the silica white loading nano silvery, and the ethanol is the ethanol that mass fraction is 60%
The aqueous solution；Mint extract described in the plant extracts and the pot marigold extract, the orange peel extract, the gold
The weight ratio of honeysuckle flower extract is 1：0.8：4：3；Bi-quaternary ammonium salt described in the modified medical stone is containing the double quaternary ammoniums of imidazolyl heterocycle
Salt, the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle include metronidazole, epoxychloropropane,
Long-chain alkyl tertiary amine；The long-chain alkyl tertiary amine is dodecyldimethylamine base tertiary amine, dodecylbenzyl methyl tertiary amine, the length
The weight ratio of dodecyldimethylamine base tertiary amine described in alkyl group tertiary amine and the dodecylbenzyl methyl tertiary amine is 1：0.24；
The preparation method of the sterilized eliminating smell agent, the preparation method of the modified medical stone, described contain imidazolyl heterocycle
The preparation method of bi-quaternary ammonium salt, the preparation method of the modified silicon rubber powder are the same as embodiment 1.
Embodiment 4
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Modified medical stone 42
Part, 9 parts of modified silicon rubber powder, 10 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, 46 parts of deionized water,
2 parts of lauric monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes thin
Lotus extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is grafted for nano medical stone
Bi-quaternary ammonium salt, the modified silicon rubber powder are the silica white loading nano silvery, and the ethanol is the ethanol that mass fraction is 60%
The aqueous solution；Mint extract described in the plant extracts and the pot marigold extract, the orange peel extract, the gold
The weight ratio of honeysuckle flower extract is 1：0.8：4：3；Bi-quaternary ammonium salt described in the modified medical stone is containing the double quaternary ammoniums of imidazolyl heterocycle
Salt, the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle include metronidazole, epoxychloropropane,
Long-chain alkyl tertiary amine；The long-chain alkyl tertiary amine is dodecyldimethylamine base tertiary amine, dodecylbenzyl methyl tertiary amine, the length
The weight ratio of dodecyldimethylamine base tertiary amine described in alkyl group tertiary amine and the dodecylbenzyl methyl tertiary amine is 1：0.1；
The preparation method of the sterilized eliminating smell agent, the preparation method of the modified medical stone, described contain imidazolyl heterocycle
The preparation method of bi-quaternary ammonium salt, the preparation method of the modified silicon rubber powder are the same as embodiment 1.
Embodiment 5
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Modified medical stone 42
Part, 9 parts of modified silicon rubber powder, 10 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, 46 parts of deionized water,
2 parts of lauric monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes thin
Lotus extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is grafted for nano medical stone
Bi-quaternary ammonium salt, the modified silicon rubber powder are the silica white loading nano silvery, and the ethanol is the ethanol that mass fraction is 60%
The aqueous solution；Mint extract described in the plant extracts and the pot marigold extract, the orange peel extract, the gold
The weight ratio of honeysuckle flower extract is 1：0.8：4：3；Bi-quaternary ammonium salt described in the modified medical stone is containing the double quaternary ammoniums of imidazolyl heterocycle
Salt, the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle include metronidazole, epoxychloropropane,
Long-chain alkyl tertiary amine；The long-chain alkyl tertiary amine is dodecyldimethylamine base tertiary amine, dodecylbenzyl methyl tertiary amine, the length
The weight ratio of dodecyldimethylamine base tertiary amine described in alkyl group tertiary amine and the dodecylbenzyl methyl tertiary amine is 1：0.6；
The preparation method of the sterilized eliminating smell agent, the preparation method of the modified medical stone, described contain imidazolyl heterocycle
The preparation method of bi-quaternary ammonium salt, the preparation method of the modified silicon rubber powder are the same as embodiment 1.
Embodiment 6
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Modified medical stone 42
Part, 9 parts of modified silicon rubber powder, 10 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, 46 parts of deionized water,
2 parts of lauric monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes thin
Lotus extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is grafted for nano medical stone
Bi-quaternary ammonium salt, the modified silicon rubber powder are the silica white loading nano silvery, and the ethanol is the ethanol that mass fraction is 60%
The aqueous solution；Mint extract described in the plant extracts and the pot marigold extract, the orange peel extract, the gold
The weight ratio of honeysuckle flower extract is 1：0.8：6：5；Bi-quaternary ammonium salt described in the modified medical stone is containing the double quaternary ammoniums of imidazolyl heterocycle
Salt, the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle include metronidazole, epoxychloropropane,
Long-chain alkyl tertiary amine；The long-chain alkyl tertiary amine is dodecyldimethylamine base tertiary amine, dodecylbenzyl methyl tertiary amine, the length
The weight ratio of dodecyldimethylamine base tertiary amine described in alkyl group tertiary amine and the dodecylbenzyl methyl tertiary amine is 1：0.24；
The preparation method of the sterilized eliminating smell agent, the preparation method of the modified medical stone, described contain imidazolyl heterocycle
The preparation method of bi-quaternary ammonium salt, the preparation method of the modified silicon rubber powder are the same as embodiment 1.
Embodiment 7
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Modified medical stone 42
Part, 9 parts of modified silicon rubber powder, 10 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, 46 parts of deionized water,
2 parts of lauric monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes thin
Lotus extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is grafted for nano medical stone
Bi-quaternary ammonium salt, the modified silicon rubber powder are the silica white loading nano silvery, and the ethanol is the ethanol that mass fraction is 60%
The aqueous solution；Mint extract described in the plant extracts and the pot marigold extract, the orange peel extract, the gold
The weight ratio of honeysuckle flower extract is 1：1：1：2；Bi-quaternary ammonium salt described in the modified medical stone is bi-quaternary ammonium salt containing imidazolyl heterocycle,
The preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle includes metronidazole, epoxychloropropane, length
Alkyl group tertiary amine；The long-chain alkyl tertiary amine is dodecyldimethylamine base tertiary amine, dodecylbenzyl methyl tertiary amine, the long-chain
The weight ratio of the tertiary amine of dodecyldimethylamine base described in alkyl tertiary amine and the dodecylbenzyl methyl tertiary amine is 1：0.24；
The preparation method of the sterilized eliminating smell agent, the preparation method of the modified medical stone, described contain imidazolyl heterocycle
The preparation method of bi-quaternary ammonium salt, the preparation method of the modified silicon rubber powder are the same as embodiment 1.
Comparative example 1
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Modified medical stone 50
Part, 9 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, 46 parts of deionized water, lauric monoglyceride
2 parts, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes mint extract, golden small cup
Flower extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is that nano medical stone is grafted bi-quaternary ammonium salt, described
Ethanol is the ethanol water that mass fraction is 60%；Mint extract described in the plant extracts carries with the pot marigold
It is 1 to take thing, the orange peel extract, the weight ratio of the Honegsukle flower P.E：0.8：4：3；Described in the modified medical stone
Bi-quaternary ammonium salt is bi-quaternary ammonium salt containing imidazolyl heterocycle, and the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle includes 1- ethoxys -2-
5-nitro imidazole, epoxychloropropane, long-chain alkyl tertiary amine；The long-chain alkyl tertiary amine be dodecyldimethylamine base tertiary amine,
Dodecylbenzyl methyl tertiary amine, dodecyldimethylamine base tertiary amine described in the long-chain alkyl tertiary amine and the dodecyl benzyl
The weight ratio of ylmethyl tertiary amine is 1：0.24；
The preparation method of the sterilized eliminating smell agent, the preparation method of the modified medical stone, described contain imidazolyl heterocycle
The preparation method of bi-quaternary ammonium salt is the sterilized eliminating smell agent noon modified silicon rubber powder with embodiment 1, difference.
Comparative example 2
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Modified medical stone 48
Part, 13 parts of modified silicon rubber powder, 1 part of neopelex, 1 part of tea tree ethereal oil, 46 parts of deionized water, lauric monoglyceride
2 parts of ester, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes mint extract, gold
Small cup flower extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is that nano medical stone is grafted bi-quaternary ammonium salt, institute
It is the silica white loading nano silvery to state modified silicon rubber powder, and the ethanol is the ethanol water that mass fraction is 60%；It is described
Mint extract described in plant extracts and the pot marigold extract, the orange peel extract, the Honegsukle flower P.E
Weight ratio be 1： 0.8：4：3；Bi-quaternary ammonium salt described in the modified medical stone is bi-quaternary ammonium salt containing imidazolyl heterocycle, described to contain
The preparing raw material of imidazolyl heterocycle bi-quaternary ammonium salt includes metronidazole, epoxychloropropane, chain alkyl
Tertiary amine；The long-chain alkyl tertiary amine is dodecyldimethylamine base tertiary amine, dodecylbenzyl methyl tertiary amine, the chain alkyl uncle
The weight ratio of the tertiary amine of dodecyldimethylamine base described in amine and the dodecylbenzyl methyl tertiary amine is 1：0.24；
The preparation method of the sterilized eliminating smell agent, the preparation method of the modified medical stone, described contain imidazolyl heterocycle
The preparation method of bi-quaternary ammonium salt, the preparation method of the modified silicon rubber powder are the sterilized taste removal with embodiment 1, difference
Without plant extracts in agent.
Comparative example 3
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Nano medical stone 42
Part, 9 parts of modified silicon rubber powder, 10 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, 46 parts of deionized water,
2 parts of lauric monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes thin
Lotus extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The ethanol is the ethanol that mass fraction is 60%
The aqueous solution；Mint extract described in the plant extracts and the pot marigold extract, the orange peel extract, the gold
The weight ratio of honeysuckle flower extract is 1：0.8：4：3；
The preparation method of the sterilized eliminating smell agent, the preparation method of the modified silicon rubber powder are distinguished with embodiment 1
Modified medical stone is replaced in the nano medical stone.
Comparative example 4
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Modified medical stone 42
Part, 9 parts of silica white, 10 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, deionized water 46 part, month
2 parts of cinnamic acid monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes peppermint
Extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The modified medical stone is that nano medical stone grafting is double
Quaternary ammonium salt, the ethanol are the ethanol water that mass fraction is 60%；Mint extract described in the plant extracts with
The pot marigold extract, the orange peel extract, the weight ratio of the Honegsukle flower P.E are 1：0.8：4：3；The modification
Bi-quaternary ammonium salt described in medical stone is bi-quaternary ammonium salt containing imidazolyl heterocycle, and the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle includes
Metronidazole, epoxychloropropane, long-chain alkyl tertiary amine；The long-chain alkyl tertiary amine is myristyl
Dimethyl tertiary amine, dodecylbenzyl methyl tertiary amine, dodecyldimethylamine base tertiary amine described in the long-chain alkyl tertiary amine and institute
The weight ratio for stating dodecylbenzyl methyl tertiary amine is 1：0.24；
The preparation method of the sterilized eliminating smell agent, the preparation method of the modified medical stone, described contain imidazolyl heterocycle
The preparation method of bi-quaternary ammonium salt is that the silica white replaces modified silicon rubber powder with embodiment 1, difference.
Comparative example 5
The sterilized eliminating smell agent, is calculated by weight, and the sterilized eliminating smell agent includes：Nano medical stone 42
Part, 9 parts of silica white, 10 parts of plant extracts, 1 part of neopelex, 1 part of tea tree ethereal oil, deionized water 46 part, month
2 parts of cinnamic acid monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, 50 parts of ethanol；The plant extracts includes peppermint
Extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；The ethanol is the ethanol water that mass fraction is 60%
Solution；Mint extract described in the plant extracts and the pot marigold extract, the orange peel extract, the gold and silver
The weight ratio of flower extract is 1：0.8：4：3；
For the preparation method of the sterilized eliminating smell agent with embodiment 1, difference is that the nano medical stone replaces being modified
Medical stone, the silica white replace modified silicon rubber powder.
Performance test：
1st, stability：Sterilized eliminating smell agent 5g is taken respectively, is placed in 10mL centrifuge tubes, is centrifuged with 4000r/min
30min, sterilized eliminating smell agent outward appearance and stretchability situation of change after centrifugation；
Stability is good：Sterilized eliminating smell agent outward appearance and stretchability have no significant change after centrifugation；
Stability is general：For sterilized eliminating smell agent outward appearance without significant change, stretchability is general, can easily apply after centrifugation
It is put on gauze, but adhesiveness dies down；
Stability is poor：Sterilized eliminating smell agent outward appearance has significant change (layering) after centrifugation, and stretchability is deteriorated, it is impossible to side
Being applied on gauze just, adhesiveness dies down.
2nd, high temperature resistant：Placed 90 days under the conditions of the sealing of sterilized eliminating smell agent is better than into 50 DEG C, observe sterilized taste removal
Agent outward appearance and stretchability situation of change；
It is good：Sterilized eliminating smell agent outward appearance and stretchability have no significant change；
Typically：Outward appearance has significant change, and stretchability is deteriorated, it is impossible to is easily applied on gauze, adhesiveness dies down；
Difference：Outward appearance has significant change (layering), and stretchability is deteriorated, it is impossible to is easily applied on gauze, adhesiveness dies down.
3rd, biocidal property
For trying bacterium：Coccobacillus, which is read, using staphylococcus aureus, Escherichia coli, pseudomonas aeruginosa and white carries out biocidal property examination
Test, be purchased from Chinese industrial Microbiological Culture Collection administrative center, CICC.
Sterilizing function is according to national standard GB21551.2-2010《The antibacterial of family expenses and similar applications electrical equipment, degerming, purification function
The particular/special requirement of anti-biotic material》Middle absorption process detects material bacteria resistance energy.
4th, taste removal
Function of odor removal is according to national standard GB21551.4-2010《The antibacterial of family expenses and similar applications electrical equipment, degerming, purification function
The particular/special requirement of refrigerator》Tested.
The performance test results of table 1
It is seen from the above data that sterilized eliminating smell agent provided by the invention its can kill Staphylococcus aureus, big
Enterobacteria, pseudomonas aeruginosa, shigella dysenteriae and white read the various bacterias such as coccobacillus, and adsorption capacity and sterilization capability are excellent, tool
There are the sterilization sterilizing of high intensity, anti-corrosion, fresh-keeping and function of odor removal.
Foregoing example is merely illustrative, some features of the feature for explaining the disclosure.Appended claim
It is intended to require the scope as wide as possible being contemplated that, and embodiments as presented herein is only according to all possible embodiment
Combination selection embodiment explanation.Therefore, the purpose of applicant is appended claim not by the explanation present invention
Feature example selectional restriction.And the progress in science and technology will not formed due to the inaccuracy of language performance and not
The possible equivalent or son being presently considered are replaced, and these changes should also be interpreted by appended in the conceived case
Claim covers.
Claims (10)
1. a kind of sterilized eliminating smell agent, it is characterised in that calculate by weight, the sterilized eliminating smell agent includes：It is modified
Medical stone 30-50 parts, modified silicon rubber powder 5-13 parts, plant extracts 2-15 parts, neopelex 0.5-3 parts, tea tree
Essential oil 0.5-2 parts, deionized water 30-60 parts, lauric monoglyceride 0.1-5 parts, dodecyl dimethyl benzyl ammonium bromide
0.5-2 parts, ethanol 30-55 parts；
Wherein, the plant extracts includes mint extract, pot marigold extract, orange peel extract, Honegsukle flower P.E；Institute
State modified medical stone and be grafted bi-quaternary ammonium salt for nano medical stone, the modified silicon rubber powder is the silica white loading nano silvery, institute
It is the ethanol water that mass fraction is 60% to state ethanol.
2. sterilized eliminating smell agent according to claim 1, it is characterised in that calculate by weight, it is described sterilized to remove
Taste agent includes：Modified medical stone 35-45 parts, modified silicon rubber powder 8-12 parts, plant extracts 2-10 parts, neopelex
0.5-2 parts, tea tree ethereal oil 0.5-2 parts, deionized water 40-50 parts, lauric monoglyceride 1-5 parts, dodecyl dimethyl benzene
Methyl bromide ammonium 0.5-2 parts, ethanol 40-55 parts.
3. sterilized eliminating smell agent according to claim 2, it is characterised in that calculate by weight, it is described sterilized to remove
Taste agent includes：Modified 42 parts of medical stone, 9 parts of modified silicon rubber powder, 10 parts of plant extracts, 1 part of neopelex, tea tree
1 part of essential oil, 46 parts of deionized water, 2 parts of lauric monoglyceride, 1 part of dodecyl dimethyl benzyl ammonium bromide, ethanol 50
Part.
4. sterilized eliminating smell agent according to claim 1, it is characterised in that peppermint described in the plant extracts is extracted
The weight ratio of thing and the pot marigold extract, the orange peel extract, the Honegsukle flower P.E is 1：(0.5-1)：(1-
6)：(2-5).
5. sterilized eliminating smell agent according to claim 4, it is characterised in that peppermint described in the plant extracts is extracted
The weight ratio of thing and the pot marigold extract, the orange peel extract, the Honegsukle flower P.E is 1：0.8：4：3.
6. sterilized eliminating smell agent according to claim 1, it is characterised in that bi-quaternary ammonium salt described in the modified medical stone
For bi-quaternary ammonium salt containing imidazolyl heterocycle, the preparing raw material of the bi-quaternary ammonium salt containing imidazolyl heterocycle includes 1- ethoxy -2- methyl -5- nitre
Base imidazoles, epoxychloropropane, long-chain alkyl tertiary amine.
7. sterilized eliminating smell agent according to claim 6, it is characterised in that the long-chain alkyl tertiary amine includes dodecyl
One kind in dimethyl tertiary amine, dodecyldimethylamine base tertiary amine, hexadecyldimethyl benzyl ammonium tertiary amine, dodecylbenzyl methyl tertiary amine
It is or a variety of.
8. sterilized eliminating smell agent according to claim 7, it is characterised in that the long-chain alkyl tertiary amine is myristyl two
Methyl tertiary amine, dodecylbenzyl methyl tertiary amine.
9. sterilized eliminating smell agent according to claim 8, it is characterised in that the tetradecane described in the long-chain alkyl tertiary amine
The weight ratio of base dimethyl tertiary amine and the dodecylbenzyl methyl tertiary amine is 1：(0.1-0.6).
10. according to the preparation method of any one of the claim 1-9 sterilized eliminating smell agents, it is characterised in that including following
Step：
(1) modified silicon rubber powder, neopelex, lauric monoglyceride, stirring are added by weight into reactor
Uniformly, 1h is stirred after being warming up to 40-50 DEG C, 50 DEG C are dried under reduced pressure 8h；
(2) modified medical stone, deionized water, dodecyl dimethyl benzyl ammonium bromide are added in mixture into step (1),
Dried after stirring；
(3) ethanol water that tea tree ethereal oil, plant extracts and mass fraction are 60% is added in the particle dried into step (2)
Solution, is stirred well mixed, obtains the sterilized eliminating smell agent.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710665905.4A CN107646885B (en) | 2017-08-07 | 2017-08-07 | High-efficiency sterilization deodorant and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710665905.4A CN107646885B (en) | 2017-08-07 | 2017-08-07 | High-efficiency sterilization deodorant and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107646885A true CN107646885A (en) | 2018-02-02 |
| CN107646885B CN107646885B (en) | 2020-05-22 |
Family
ID=61128706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710665905.4A Active CN107646885B (en) | 2017-08-07 | 2017-08-07 | High-efficiency sterilization deodorant and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107646885B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110420342A (en) * | 2019-06-21 | 2019-11-08 | 苟小平 | A kind of deodorant for refrigerator |
| CN114287451A (en) * | 2021-12-31 | 2022-04-08 | 上海纳米技术及应用国家工程研究中心有限公司 | Preparation method of natural plant modified antibacterial liquid and product thereof |
| CN116159172A (en) * | 2023-04-20 | 2023-05-26 | 北京安吉贝玛健康科技有限公司 | Efficient deodorant and preparation method thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1168765A (en) * | 1996-06-17 | 1997-12-31 | 安永 | Strong deodorizing and sterilizing agent |
| CN1623897A (en) * | 2004-11-19 | 2005-06-08 | 中国乐凯胶片集团公司 | Process for preparing silicon dioxide of carrying nano silver |
| CN101263826A (en) * | 2007-03-14 | 2008-09-17 | 范翔 | Silver ion antimicrobial agent and dry method production process |
| CN102847509A (en) * | 2012-04-17 | 2013-01-02 | 东北农业大学 | Adsorbent for mycotoxin in feed and preparation method thereof |
| CN105776459A (en) * | 2016-05-11 | 2016-07-20 | 上海立昌环境工程股份有限公司 | Environment-friendly flocculating agent applicable to painting workshop circulation water treatment, and preparation method and application thereof |
-
2017
- 2017-08-07 CN CN201710665905.4A patent/CN107646885B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1168765A (en) * | 1996-06-17 | 1997-12-31 | 安永 | Strong deodorizing and sterilizing agent |
| CN1623897A (en) * | 2004-11-19 | 2005-06-08 | 中国乐凯胶片集团公司 | Process for preparing silicon dioxide of carrying nano silver |
| CN101263826A (en) * | 2007-03-14 | 2008-09-17 | 范翔 | Silver ion antimicrobial agent and dry method production process |
| CN102847509A (en) * | 2012-04-17 | 2013-01-02 | 东北农业大学 | Adsorbent for mycotoxin in feed and preparation method thereof |
| CN105776459A (en) * | 2016-05-11 | 2016-07-20 | 上海立昌环境工程股份有限公司 | Environment-friendly flocculating agent applicable to painting workshop circulation water treatment, and preparation method and application thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110420342A (en) * | 2019-06-21 | 2019-11-08 | 苟小平 | A kind of deodorant for refrigerator |
| CN114287451A (en) * | 2021-12-31 | 2022-04-08 | 上海纳米技术及应用国家工程研究中心有限公司 | Preparation method of natural plant modified antibacterial liquid and product thereof |
| CN114287451B (en) * | 2021-12-31 | 2022-12-27 | 上海纳米技术及应用国家工程研究中心有限公司 | Preparation method of natural plant modified antibacterial liquid and product thereof |
| CN116159172A (en) * | 2023-04-20 | 2023-05-26 | 北京安吉贝玛健康科技有限公司 | Efficient deodorant and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107646885B (en) | 2020-05-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Pirzada et al. | Antifungal activity of Dodonaea viscosa Jacq extract on pathogenic fungi isolated from super ficial skin infection. | |
| WO2006109898A1 (en) | Antimicrobial composition containing natural extract, nano silver and natural essential oil | |
| CN107398172A (en) | It is a kind of efficiently to remove formaldehyde air purifying preparation | |
| CN107646885A (en) | A kind of sterilized eliminating smell agent and preparation method thereof | |
| CN105727337A (en) | Traditional Chinese medicine antimicrobial air freshener and preparation method thereof | |
| CN103494741A (en) | Pure natural preservative for cosmetics | |
| CN111265598A (en) | Composite broad-spectrum antibacterial agent and preparation method thereof | |
| CN105131398A (en) | Antimicrobial and mildew resistant preservative film and preparation method thereof | |
| CN102406559A (en) | Oral cavity refreshing spray with functions of diminishing inflammation and stopping bleeding and preparation method for oral cavity refreshing spray | |
| CN108684743A (en) | A kind of sheep hurdle air sanitizer and preparation method thereof | |
| CN104997917A (en) | Gynecological traditional Chinese medicine composition containing nano-silver | |
| CN107183076A (en) | A kind of plants antimicrobial additive and preparation method thereof | |
| CN106511114A (en) | Broad spectrum bactericidal pure natural orange extract essence and preparation method thereof | |
| CN107320758B (en) | Air purifying agent for efficiently removing bacteria in livestock and poultry breeding environment | |
| CN110402969B (en) | Green environment-friendly plant source disinfectant | |
| CN103462860A (en) | Compound preservative for cosmetics | |
| CN107519328A (en) | A kind of radix tetrastigme antimicrobial fluid and preparation method thereof | |
| CN104524616A (en) | Preparation method of traditional Chinese medicine air freshener | |
| CN108815546B (en) | Lemon-flavored natural plant freshener with insect expelling and antibacterial functions | |
| CN111838211A (en) | Mite and odor removing plant extract combined liquid, method and application | |
| CN111345325A (en) | Method for preparing disinfectant by using Chinese herbal medicine brewing technology | |
| CN104164126B (en) | Architectural indoor putty capable of purifying air, inhibiting bacteria and repelling mosquitoes and preparation method of architectural indoor putty | |
| CN105111710A (en) | Bus and subway handle with antibacterial and healthcare function and preparation method thereof | |
| CN104231709A (en) | Green environment-friendly long-acting antibacterial putty and preparation method | |
| CN111528233A (en) | Sterilization disinfectant and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20210615 Address after: One of the 1st floor of workshop 1 of Zhaoqing health family Industrial Co., Ltd., Shali Industrial Park, Zhaoqing hi tech Zone, Guangdong Province Patentee after: Qingdajie Biotechnology Co.,Ltd. Address before: 154000 No.48, group 19, beitiexi community, Xiangyang District, Jiamusi City, Heilongjiang Province Patentee before: Wu Yang Patentee before: Xing Yucheng Patentee before: Wang Zhenzhou |
|
| PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
| PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: An efficient sterilization and deodorant and its preparation method Effective date of registration: 20231107 Granted publication date: 20200522 Pledgee: Hi tech Zone Technology sub branch of Guangdong Sihui Rural Commercial Bank Co.,Ltd. Pledgor: Qingdajie Biotechnology Co.,Ltd. Registration number: Y2023980064487 |