CN107638376A - A kind of anti-wrinkle skin care item containing Chinese herbaceous peony stem cell extract - Google Patents
A kind of anti-wrinkle skin care item containing Chinese herbaceous peony stem cell extract Download PDFInfo
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Abstract
The invention discloses a kind of anti-wrinkle composition, the composition includes the composition of following parts by weight：1.4~7 parts of 0.04~2.1 part of Chinese herbaceous peony stem cell extract, 1.2~5 parts of Margarita extract, 0.7~11 part of Hippocampus extract, 2.3~12 parts of Rhizoma Gastrodiae extract and Hericium erinaceus extract.Meanwhile the invention also discloses the skin care item containing above-mentioned anti-wrinkle composition.The anti-wrinkle skin care item of the present invention include Chinese herbaceous peony stem cell extract, Margarita extract, Hippocampus extract, Rhizoma Gastrodiae extract and Hericium erinaceus extract, their nutriment is grouped together, facial wrinkles can effectively be dispelled, simultaneously, black-eyed degree can also be mitigated, wherein and preservative is free of, it is useful and harmless to skin.
Description
Technical field
The present invention relates to a kind of anti-wrinkle skin care item, especially a kind of anti-wrinkle skin care item containing Chinese herbaceous peony stem cell extract.
Background technology
It is the nature of each women to like to be beautiful, and no one wishes appearance wrinkle too early in oneself smooth facial skin.Wrinkle
The reason for line is the mark of skin senescence, and the formation of wrinkle is mainly due to inside, wherein, body cell aging is person in middle and old age female
Property produce wrinkle most the underlying cause.According to the rule of science of heredity, with advancing age, cytoactive gradually reduces, metabolism
Reduced capability, neonatal cell number speedup is caused to be less than cell senescence speed, aged cells hydratability is low and light aging is made
With enhancing, cause skin shrinkage and moisture retention declines, aggravate fibr tissue and deteriorate, dry skin easily goes out microgroove.In addition, skin
Aging also aggravates skin corrupted and degree of drying along with sweat gland system degradation, hyposteatosis, and skin elasticity is reduced, lured
Wrinkle is sent out to produce.
On October 25th, 2010, Nature Biotechnology have delivered the research institute of the Unhwa Corp companies of South Korea
It is successfully separated first and has cultivated the paper of plant stem cell, and certification has been obtained to the identity of plant stem cell, plant does
The research of cell enters the stage of high speed development.
In simple terms, there are two " group " cells for being located at plant tip in plant, they have powerful self-renewing
Ability, it can not only be divided into autogenous cell, moreover it is possible to other any plant cells are divided into, are qualified " general-purpose cells ",
Moreover, they, which also have, continues splitting ability so that many large-scale plant existences more than thousand.
2012, " plant stem cell " technology was studied in the effect of beauty and health care field and has been achieved for certain progress,
Metabolism of the plant stem cell to raising skin is proved, improves microcirculation, tightening up and recovering skin elasticity has major application
Value.
The content of the invention
Based on this, provide it is an object of the invention to overcome above-mentioned the deficiencies in the prior art part and effectively dispel skin wrinkle
The skin care item of line, the skin care item are free of preservative, safe and non-toxic to skin.
To achieve the above object, the technical scheme taken of the present invention is：
A kind of anti-wrinkle composition, the composition include the composition of following parts by weight：Chinese herbaceous peony stem cell extract 0.04~
2.1 parts, 1.2~5 parts of Margarita extract, 0.7~11 part of Hippocampus extract, 2.3~12 parts of Rhizoma Gastrodiae extract and Hericium erinaceus extraction
1.4~7 parts of thing.
Wherein, Chinese herbaceous peony stem cell can play interference effect by epigenetic factor pair human skin cell, can be effective
The power of regeneration of skin progenitor cell is encouraged, hyperplasia fibrillar structure albumen, accelerates self more raw and reparation of skin；Modern study shows
Pearl all has the function that uniqueness in raising body immunity, anti-aging, freckle removing and whitening, supplement calcium etc.；Hippocampus is
A kind of higher rare Chinese medicine of economic value, have physical fitness, tonifying kidney and strengthening yang, relaxing tendons and activating collaterals, anti-inflammatory analgetic, tranquilizing and allaying excitement,
It is relieving cough and asthma to wait medicinal function；《Japan hanako materia medica》Record rhizoma Gastrodiae can aid yang qi, mend general debility, promoting blood circulation, have one's ideas straightened out；It is modern
Medical science and pharmacological many researchs are summarised as improving immunity, antitumor, anti-aging, drop to the medicinal efficacy of hericium erinaceum polysaccharide
The different physiological roles such as blood fat.
Preferably, the mass ratio of the Chinese herbaceous peony stem cell extract and Hericium erinaceus extract is 0.15~0.7:2.8.It is more excellent
Selection of land, the mass ratio of the Chinese herbaceous peony stem cell extract and Hericium erinaceus extract is 0.4:2.8.Present inventor is through multiple
Experiment is found, when the mass ratio of Chinese herbaceous peony stem cell extract and Hericium erinaceus extract is 0.15~0.7 in skin care item:When 2.8, shield
The anti-wrinkle effect of skin product is preferable；When the mass ratio of Chinese herbaceous peony stem cell extract and Hericium erinaceus extract is 0.4 in skin care item:2.8
When, the anti-wrinkle of skin care item is better.
Preferably, the mass ratio of the Chinese herbaceous peony stem cell extract, Margarita extract and Rhizoma Gastrodiae extract is 0.1~0.5:
2.3:4~6.It is highly preferred that the mass ratio of the Chinese herbaceous peony stem cell extract, Margarita extract and Rhizoma Gastrodiae extract is 0.28:
2.3:5.6.Present inventor has found through test of many times, when Chinese herbaceous peony stem cell extract in skin care item, Margarita extract and
The mass ratio of Rhizoma Gastrodiae extract is 0.1~0.5:2.3:When 4~6, the black-eyed ability of dispelling of skin care item is preferable；When in skin care item
The mass ratio of Chinese herbaceous peony stem cell extract, Margarita extract and Rhizoma Gastrodiae extract is 0.28:2.3:When 5.6, dispelling for skin care item is black
The ability of eyelet is preferable.
Preferably, the composition includes the composition of following parts by weight：0.28 part of Chinese herbaceous peony stem cell extract, pearl extraction
1.96 parts of 2 parts of thing, 7.7 parts of Hippocampus extract, 5.6 parts of Rhizoma Gastrodiae extract and Hericium erinaceus extract.Present inventor's warp is more
It is secondary experiment find, when in skin care item contain 0.28 part of Chinese herbaceous peony stem cell extract, 2 parts of Margarita extract, Hippocampus extract 7.7
Part, 5.6 parts of Rhizoma Gastrodiae extract and during 1.96 parts of Hericium erinaceus extract, the anti-wrinkle of skin care item and black-eyed ability of dispelling are all good.
As the second aspect of the invention, present invention also offers a kind of anti-wrinkle skin care item, the anti-wrinkle skin care item bag
Containing above-mentioned composition.
Preferably, Chinese herbaceous peony stem cell extract, Margarita extract, Hippocampus extract, Rhizoma Gastrodiae extract in the skin care item
Quality percentage total amount with Hericium erinaceus extract is 7.6~11.7%.Present inventor has found through test of many times, works as skin care
Chinese herbaceous peony stem cell extract in product, Margarita extract, Hippocampus extract, the quality percentage of Rhizoma Gastrodiae extract and Hericium erinaceus extract
When total amount is 7.6~11.7%, the anti-wrinkle of skin care item is better.
Preferably, the Chinese herbaceous peony stem cell extract is prepared by the following：
S1, Chinese herbaceous peony new life root or branch sterilization, after removing xylem and marrow, it is inoculated in inducing culture, Fiber differentiation
Obtain cambial cell；
S2, the cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is described it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain Chinese herbaceous peony stem cell；
S4, gained Chinese herbaceous peony stem cell obtain described Chinese herbaceous peony stem cell through the micro-nano method broken wall of low temperature, then by water extraction
Extract.
Wherein, the micro-nano method broken wall of low temperature refers to make its freezing in a low temperature of Chinese herbaceous peony stem cell is placed on into -170 DEG C, then
Melt at normal temperatures, so repeatedly so that the cell membrane of Chinese herbaceous peony stem cell crushes；This method can by the vital activity of stem cell with
Power of regeneration is assigned in skin care item, is absorbed via skin, can be remarkably promoted nutrition and be penetrated into and absorb, can effectively lift skin actively
Property, improve skin quality from cell aspect.
Preferably, the Margarita extract is prepared by the following：Pearl is after the processing of high speed bead mill method, using water extraction
Method obtains Margarita extract；
The Hippocampus extract is prepared by the following：Hippocampus meat is taken after the processing of high speed bead mill method, using alcohol extracting method
Obtain Hippocampus extract；
The Rhizoma Gastrodiae extract is prepared by the following：Rhizoma Gastrodiae is taken after the micro-nano method broken wall of low temperature, using water extraction
Obtain mangosteen extract；
The Hericium erinaceus extract is prepared by the following：Rhizoma Gastrodiae is taken after the micro-nano method processing of low temperature, using alcohol extracting
Method obtains Hericium erinaceus extract.Wherein, the preferred methanol of alcohol or ethanol in the alcohol extracting method.
Relative to prior art, beneficial effects of the present invention are：
The anti-wrinkle skin care item of the present invention include Chinese herbaceous peony stem cell extract, Margarita extract, Hippocampus extract, rhizoma Gastrodiae extraction
Thing and Hericium erinaceus extract, their nutriment are grouped together, and can effectively dispel facial wrinkles, at the same time it can also subtract
Light black-eyed degree, wherein and be free of preservative, it is useful and harmless to skin.
Embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
Embodiment 1
A kind of embodiment of the anti-wrinkle composition of the present invention, the composition include the composition of following parts by weight：Chinese herbaceous peony does
0.04 part of cell extract, 5 parts of Margarita extract, 0.7 part of Hippocampus extract, 12 parts of Rhizoma Gastrodiae extract and Hericium erinaceus extract
1.4 part.
A kind of embodiment of the anti-wrinkle skin care item of the present invention, includes above-mentioned anti-wrinkle composition, and isopropyl palmitate
63 parts of 35 parts, 5.4 parts of glycerine, 18 parts of Arabic gum and water, wherein, Chinese herbaceous peony stem cell extract, pearl extraction in skin care item
Thing, Hippocampus extract, the quality percentage total amount of Rhizoma Gastrodiae extract and Hericium erinaceus extract are 17.8%.
The preparation method of above-mentioned anti-wrinkle skin care item comprises the following steps：
(1) Chinese herbaceous peony stem cell extract is prepared by the following：
S1, the sterilization of Chinese herbaceous peony new life root, after removing xylem and marrow, inducing culture is inoculated in, Fiber differentiation obtains shape
Into confluent monolayer cells；
S2, the cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is described it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain Chinese herbaceous peony stem cell；
S4, gained Chinese herbaceous peony stem cell obtain described Chinese herbaceous peony stem cell through the micro-nano method broken wall of low temperature, then by water extraction
Extract.
Wherein, the micro-nano method broken wall of low temperature refers to make its freezing in a low temperature of Chinese herbaceous peony stem cell is placed on into -170 DEG C, then
Melt at normal temperatures, so repeatedly so that the cell membrane of Chinese herbaceous peony stem cell crushes；
(2) Margarita extract is prepared by the following：Pearl obtains treasure after the processing of high speed bead mill method using water extraction
Pearl extract；
Hippocampus extract is prepared by the following：Hippocampus meat is taken to be obtained after the processing of high speed bead mill method using methanol formulation
To Hippocampus extract；
Rhizoma Gastrodiae extract is prepared by the following：Rhizoma Gastrodiae is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
Mangosteen extract；
Hericium erinaceus extract is prepared by the following：Rhizoma Gastrodiae is taken after the micro-nano method processing of low temperature, using ethanol formulation
Obtain Hericium erinaceus extract；
(3) by Margarita extract, Hippocampus extract, Rhizoma Gastrodiae extract and Hericium erinaceus extract and isopropyl palmitate 35
Part, 5.4 parts of glycerine, 18 parts of Arabic gum and 63 parts of mixing of water, after 36.7 degrees Celsius stir, are filtered to remove superfluous water
Point, lotion is obtained, then addition Chinese herbaceous peony stem cell extract, which is uniformly dispersed, produces a kind of anti-wrinkle face cream.
Embodiment 2
A kind of embodiment of the anti-wrinkle composition of the present invention, the composition include the composition of following parts by weight：Chinese herbaceous peony does
1.1 parts of cell extract, 4 parts of Margarita extract, 2.2 parts of Hippocampus extract, 8.7 parts of Rhizoma Gastrodiae extract and Hericium erinaceus extract
3.5 part.
A kind of embodiment of the anti-wrinkle skin care item of the present invention, includes above-mentioned anti-wrinkle composition, and isopropyl palmitate
85 parts of 45 parts, 7 parts of glycerine, 36 parts of Arabic gum and water, wherein, Chinese herbaceous peony stem cell extract in skin care item, Margarita extract,
The quality percentage total amount of Hippocampus extract, Rhizoma Gastrodiae extract and Hericium erinaceus extract is 11.7%.
The preparation method of above-mentioned anti-wrinkle skin care item comprises the following steps：
(1) Chinese herbaceous peony stem cell extract is prepared by the following：
S1, the sterilization of Chinese herbaceous peony new life branch, after removing xylem and marrow, inducing culture is inoculated in, Fiber differentiation obtains shape
Into confluent monolayer cells；
S2, the cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is described it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain Chinese herbaceous peony stem cell；
S4, gained Chinese herbaceous peony stem cell obtain described Chinese herbaceous peony stem cell through the micro-nano method broken wall of low temperature, then by water extraction
Extract.
Wherein, the micro-nano method broken wall of low temperature refers to make its freezing in a low temperature of Chinese herbaceous peony stem cell is placed on into -170 DEG C, then
Melt at normal temperatures, so repeatedly so that the cell membrane of Chinese herbaceous peony stem cell crushes；
(2) Margarita extract is prepared by the following：Pearl obtains treasure after the processing of high speed bead mill method using water extraction
Pearl extract；
Hippocampus extract is prepared by the following：Hippocampus meat is taken to be obtained after the processing of high speed bead mill method using methanol formulation
To Hippocampus extract；
Rhizoma Gastrodiae extract is prepared by the following：Rhizoma Gastrodiae is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
Mangosteen extract；
Hericium erinaceus extract is prepared by the following：Rhizoma Gastrodiae is taken after the micro-nano method processing of low temperature, using methanol formulation
Obtain Hericium erinaceus extract；
(3) by Margarita extract, Hippocampus extract, Rhizoma Gastrodiae extract and Hericium erinaceus extract and isopropyl palmitate 45
Part, 7 parts of glycerine, 36 parts of Arabic gum and 85 parts of mixing of water, after 38 degrees Celsius stir, are filtered to remove excessive moisture,
Lotion is obtained, then addition Chinese herbaceous peony stem cell extract, which is uniformly dispersed, produces a kind of anti-wrinkle face cream.
Embodiment 3
A kind of embodiment of the anti-wrinkle composition of the present invention, the composition include the composition of following parts by weight：Chinese herbaceous peony does
0.28 part of cell extract, 2.3 parts of Margarita extract, 7.7 parts of Hippocampus extract, 5.6 parts of Rhizoma Gastrodiae extract and Hericium erinaceus extraction
1.96 parts of thing.
A kind of embodiment of the anti-wrinkle skin care item of the present invention, includes above-mentioned anti-wrinkle composition, and isopropyl palmitate
123 parts of 64 parts, 14 parts of glycerine, 55 parts of Arabic gum and water, wherein, Chinese herbaceous peony stem cell extract, pearl extraction in skin care item
Thing, Hippocampus extract, the quality percentage total amount of Rhizoma Gastrodiae extract and Hericium erinaceus extract are 7.6%.
The preparation method of above-mentioned anti-wrinkle skin care item comprises the following steps：
(1) Chinese herbaceous peony stem cell extract is prepared by the following：
S1, the sterilization of Chinese herbaceous peony new life root, after removing xylem and marrow, inducing culture is inoculated in, Fiber differentiation obtains shape
Into confluent monolayer cells；
S2, the cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is described it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain Chinese herbaceous peony stem cell；
S4, gained Chinese herbaceous peony stem cell obtain described Chinese herbaceous peony stem cell through the micro-nano method broken wall of low temperature, then by water extraction
Extract.
Wherein, the micro-nano method broken wall of low temperature refers to make its freezing in a low temperature of Chinese herbaceous peony stem cell is placed on into -170 DEG C, then
Melt at normal temperatures, so repeatedly so that the cell membrane of Chinese herbaceous peony stem cell crushes；
(2) Margarita extract is prepared by the following：Pearl obtains treasure after the processing of high speed bead mill method using water extraction
Pearl extract；
Hippocampus extract is prepared by the following：Hippocampus meat is taken to be obtained after the processing of high speed bead mill method using ethanol formulation
To Hippocampus extract；
Rhizoma Gastrodiae extract is prepared by the following：Rhizoma Gastrodiae is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
Mangosteen extract；
Hericium erinaceus extract is prepared by the following：Rhizoma Gastrodiae is taken after the micro-nano method processing of low temperature, using ethanol formulation
Obtain Hericium erinaceus extract；
(3) by Margarita extract, Hippocampus extract, Rhizoma Gastrodiae extract and Hericium erinaceus extract and isopropyl palmitate 64
Part, 14 parts of glycerine, 55 parts of Arabic gum and 123 parts of mixing of water, after 37 degrees Celsius stir, are filtered to remove superfluous water
Point, lotion is obtained, then addition Chinese herbaceous peony stem cell extract, which is uniformly dispersed, produces a kind of anti-wrinkle face cream.
Embodiment 4
A kind of embodiment of the anti-wrinkle composition of the present invention, the composition include the composition of following parts by weight：Chinese herbaceous peony does
1.7 parts of cell extract, 3 parts of Margarita extract, 9.3 parts of Hippocampus extract, 3.4 parts of Rhizoma Gastrodiae extract and Hericium erinaceus extract
5.6 part.
A kind of embodiment of the anti-wrinkle skin care item of the present invention, includes above-mentioned anti-wrinkle composition, and isopropyl palmitate
91st, 131 parts of 24 parts of glycerine, 47 parts of Arabic gum and water, wherein, Chinese herbaceous peony stem cell extract in skin care item, Margarita extract,
The quality percentage total amount of Hippocampus extract, Rhizoma Gastrodiae extract and Hericium erinaceus extract is 8.1%.
The preparation method of above-mentioned anti-wrinkle skin care item comprises the following steps：
(1) Chinese herbaceous peony stem cell extract is prepared by the following：
S1, the sterilization of Chinese herbaceous peony new life branch, after removing xylem and marrow, inducing culture is inoculated in, Fiber differentiation obtains shape
Into confluent monolayer cells；
S2, the cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is described it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain Chinese herbaceous peony stem cell；
S4, gained Chinese herbaceous peony stem cell obtain described Chinese herbaceous peony stem cell through the micro-nano method broken wall of low temperature, then by water extraction
Extract.
Wherein, the micro-nano method broken wall of low temperature refers to make its freezing in a low temperature of Chinese herbaceous peony stem cell is placed on into -170 DEG C, then
Melt at normal temperatures, so repeatedly so that the cell membrane of Chinese herbaceous peony stem cell crushes；
(2) Margarita extract is prepared by the following：Pearl obtains treasure after the processing of high speed bead mill method using water extraction
Pearl extract；
Hippocampus extract is prepared by the following：Hippocampus meat is taken to be obtained after the processing of high speed bead mill method using ethanol formulation
To Hippocampus extract；
Rhizoma Gastrodiae extract is prepared by the following：Rhizoma Gastrodiae is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
Mangosteen extract；
Hericium erinaceus extract is prepared by the following：Rhizoma Gastrodiae is taken after the micro-nano method processing of low temperature, using methanol formulation
Obtain Hericium erinaceus extract；
(3) by Margarita extract, Hippocampus extract, Rhizoma Gastrodiae extract and Hericium erinaceus extract and isopropyl palmitate 91,
131 parts of 24 parts of glycerine, 47 parts of Arabic gum and water Arabic gum mixing, after 39 degrees Celsius stir, are filtered to remove more
Remaining moisture, lotion is obtained, then addition Chinese herbaceous peony stem cell extract, which is uniformly dispersed, produces a kind of anti-wrinkle face cream.
Embodiment 5
A kind of embodiment of the anti-wrinkle composition of the present invention, the composition include the composition of following parts by weight：Chinese herbaceous peony does
2.1 parts of cell extract, 1.2 parts of Margarita extract, 11 parts of Hippocampus extract, 2.3 parts of Rhizoma Gastrodiae extract and Hericium erinaceus extract 7
Part.
A kind of embodiment of the anti-wrinkle skin care item of the present invention, includes above-mentioned anti-wrinkle composition, and isopropyl palmitate
122 parts of 53 parts, 17 parts of glycerine, 42 parts of Arabic gum and water, wherein, Chinese herbaceous peony stem cell extract, pearl extraction in skin care item
Thing, Hippocampus extract, the quality percentage total amount of Rhizoma Gastrodiae extract and Hericium erinaceus extract are 10.8%.
The preparation method of above-mentioned anti-wrinkle skin care item comprises the following steps：
(1) Chinese herbaceous peony stem cell extract is prepared by the following：
S1, the sterilization of Chinese herbaceous peony new life root, after removing xylem and marrow, inducing culture is inoculated in, Fiber differentiation obtains shape
Into confluent monolayer cells；
S2, the cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is described it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain Chinese herbaceous peony stem cell；
S4, gained Chinese herbaceous peony stem cell obtain described Chinese herbaceous peony stem cell through the micro-nano method broken wall of low temperature, then by water extraction
Extract.
Wherein, the micro-nano method broken wall of low temperature refers to make its freezing in a low temperature of Chinese herbaceous peony stem cell is placed on into -170 DEG C, then
Melt at normal temperatures, so repeatedly so that the cell membrane of Chinese herbaceous peony stem cell crushes；
(2) Margarita extract is prepared by the following：Pearl obtains treasure after the processing of high speed bead mill method using water extraction
Pearl extract；
Hippocampus extract is prepared by the following：Hippocampus meat is taken to be obtained after the processing of high speed bead mill method using ethanol formulation
To Hippocampus extract；
Rhizoma Gastrodiae extract is prepared by the following：Rhizoma Gastrodiae is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
Mangosteen extract；
Hericium erinaceus extract is prepared by the following：Rhizoma Gastrodiae is taken after the micro-nano method processing of low temperature, using methanol formulation
Obtain Hericium erinaceus extract；
(3) by Margarita extract, Hippocampus extract, Rhizoma Gastrodiae extract and Hericium erinaceus extract and isopropyl palmitate 53
Part, 17 parts of glycerine, 42 parts of Arabic gum and 122 parts of mixing of water, after 37.5 degrees Celsius stir, are filtered to remove superfluous water
Point, lotion is obtained, then addition Chinese herbaceous peony stem cell extract, which is uniformly dispersed, produces a kind of anti-wrinkle face cream.
The anti-wrinkle measure of merit of the anti-wrinkle skin care item of the present invention of embodiment 6
Test object：The face cream of embodiment 1~5 and face cream as a control group, wherein, control group face cream includes
Control group 1~4, the face cream of control group 1~4 compared with Example 3, differ only in Chinese herbaceous peony stem cell extract and Hericium erinaceus
The mass ratio of extract is different；The mass ratio of Chinese herbaceous peony stem cell extract and Hericium erinaceus extract in the face cream of control group 1~4
It is 0.15 successively：2.8；0.32：2.8；0.57：2.8；0.7：2.8.
Method of testing：The men and women 90 at 35~53 years old age is chosen, 9 groups is randomly divided into, every group 10, uses implement respectively
The face cream of example 1~5 and the face cream of control group 1~4；Each group member is counted first using the wrinkle quantity before face cream, is used
Preceding face cleaning, face place wrinkly is then uniformly smeared, once in the morning and once at night, after 3 months, counts each group member's facial wrinkles
Quantity, then calculate the average quantity that the wrinkle of each group user is reduced.
Test result：It is as shown in table 1 below；
The anti-wrinkle effect of the anti-wrinkle face cream of the present invention of table 1
| Face cream | Wrinkle averagely reduces quantity | Face cream | Wrinkle averagely reduces quantity |
| Embodiment 1 | 0.85 | Control group 1 | 3.54 |
| Embodiment 2 | 1.42 | Control group 2 | 3.9 |
| Embodiment 3 | 5.7 | Control group 3 | 3.78 |
| Embodiment 4 | 1.67 | Control group 4 | 3.51 |
| Embodiment 5 | 1.74 |
Interpretation of result：It was found from upper table 1, the anti-wrinkle abilities of the skin care item of embodiment 3 and the skin care item of control group 1~4 compared with
It is good；Wherein, with the anti-wrinkle ability highest of the face cream of embodiment 3.
The livid ring around eye measure of merit of dispelling of the anti-wrinkle skin care item of the present invention of embodiment 7
Test object：The face cream of embodiment 1~5 and face cream as a control group, wherein, control group face cream includes
Control group 1~4, the face cream of control group 1~4 compared with Example 3, differ only in Chinese herbaceous peony stem cell extract, pearl carries
Take thing different with the mass ratio of Rhizoma Gastrodiae extract；Chinese herbaceous peony stem cell extract, Margarita extract in the face cream of control group 1~4
Mass ratio with Rhizoma Gastrodiae extract is 0.1 successively：2.3：6；0.2：2.3：5；0.4：2.3：4.5；0.5：2.3：4.
Method of testing：Choosing 28~49 years old has black-eyed working clan 108, is randomly divided into 9 groups, every group of 12 people, distinguishes
Use the face cream of embodiment 1~5 and the face cream of control group 1~4；For the first time before use, counting the black eye of each group member respectively
Size is enclosed, using face cleaning before face cream, once in the morning and once at night, using the livid ring around eye size that each group member is counted after 120 days,
Calculate the average magnitude of each group livid ring around eye area reduction.
Test result：It is as shown in table 2 below；
The black-eyed effect of dispelling of the face cream of the present invention of table 2
Interpretation of result：It was found from upper table 2, the face cream of embodiment 3 and the face cream of control group 1~4, which have, preferably dispels
Black-eyed effect, wherein, the best results for black smoke circle of being dispelled with the face cream of embodiment 3.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than the present invention is protected
The limitation of scope is protected, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should
Understand, technical scheme can be modified or equivalent substitution, without departing from the essence of technical solution of the present invention
And scope.
Claims (10)
1. a kind of anti-wrinkle composition, it is characterised in that the composition includes the composition of following parts by weight：Chinese herbaceous peony stem cell is extracted
0.04~2.1 part of thing, 1.2~5 parts of Margarita extract, 0.7~11 part of Hippocampus extract, 2.3~12 parts of Rhizoma Gastrodiae extract and monkey
1.4~7 parts of head mushroom extract.
2. anti-wrinkle composition according to claim 1, it is characterised in that the Chinese herbaceous peony stem cell extract and Hericium erinaceus carry
The mass ratio for taking thing is 0.15~0.7:2.8.
3. anti-wrinkle composition according to claim 2, it is characterised in that the Chinese herbaceous peony stem cell extract and Hericium erinaceus carry
The mass ratio for taking thing is 0.4:2.8.
4. anti-wrinkle composition according to claim 1, it is characterised in that the Chinese herbaceous peony stem cell extract, pearl extraction
The mass ratio of thing and Rhizoma Gastrodiae extract is 0.1~0.5:2.3:4~6.
5. anti-wrinkle composition according to claim 4, it is characterised in that the Chinese herbaceous peony stem cell extract, pearl extraction
The mass ratio of thing and Rhizoma Gastrodiae extract is 0.28:2.3:5.6.
6. anti-wrinkle composition according to claim 1, it is characterised in that the composition include following parts by weight into
Point：0.28 part of Chinese herbaceous peony stem cell extract, 2 parts of Margarita extract, 7.7 parts of Hippocampus extract, 5.6 parts of Rhizoma Gastrodiae extract and hedgehog hydnum
1.96 parts of mushroom extract.
7. a kind of anti-wrinkle skin care item, it is characterised in that the anti-wrinkle skin care item are included as described in any one of claim 1~6
Composition.
8. anti-wrinkle skin care item according to claim 7, it is characterised in that Chinese herbaceous peony stem cell extract in the skin care item,
Margarita extract, Hippocampus extract, the quality percentage total amount of Rhizoma Gastrodiae extract and Hericium erinaceus extract are 7.6~11.7%.
9. anti-wrinkle skin care item according to claim 7, it is characterised in that the Chinese herbaceous peony stem cell extract passes through with lower section
Method obtains：
S1, Chinese herbaceous peony new life root or branch sterilization, after removing xylem and marrow, inducing culture is inoculated in, Fiber differentiation obtains
Cambial cell；
S2, the cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is described it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain Chinese herbaceous peony stem cell；
S4, gained Chinese herbaceous peony stem cell obtain described Chinese herbaceous peony stem cell extraction through the micro-nano method broken wall of low temperature, then by water extraction
Thing.
10. anti-wrinkle skin care item according to claim 7, it is characterised in that the Margarita extract obtains by the following method
：Pearl obtains Margarita extract after the processing of high speed bead mill method using water extraction；
The Hippocampus extract is prepared by the following：Hippocampus meat is taken to be obtained after the processing of high speed bead mill method using alcohol extracting method
Hippocampus extract；
The Rhizoma Gastrodiae extract is prepared by the following：Rhizoma Gastrodiae is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
Mangosteen extract；
The Hericium erinaceus extract is prepared by the following：Rhizoma Gastrodiae is taken to be obtained after the micro-nano method processing of low temperature using alcohol extracting method
To Hericium erinaceus extract.
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| CN201711062395.8A CN107638376A (en) | 2017-11-01 | 2017-11-01 | A kind of anti-wrinkle skin care item containing Chinese herbaceous peony stem cell extract |
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| CN201711062395.8A CN107638376A (en) | 2017-11-01 | 2017-11-01 | A kind of anti-wrinkle skin care item containing Chinese herbaceous peony stem cell extract |
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| CN1119544A (en) * | 1995-08-11 | 1996-04-03 | 许昌杰 | Face-beautifying oral liquor and its preparation method |
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Application publication date: 20180130 |