CN107616937B - Composition with antibacterial effect and wet tissue containing composition - Google Patents
Composition with antibacterial effect and wet tissue containing composition Download PDFInfo
- Publication number
- CN107616937B CN107616937B CN201710887082.XA CN201710887082A CN107616937B CN 107616937 B CN107616937 B CN 107616937B CN 201710887082 A CN201710887082 A CN 201710887082A CN 107616937 B CN107616937 B CN 107616937B
- Authority
- CN
- China
- Prior art keywords
- composition
- extract
- water
- antibacterial effect
- parts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention relates to the technical field of daily necessities, and particularly discloses a composition with an antibacterial effect and a wet tissue containing the composition. The composition comprises an elecampane extract and a polygonum cuspidatum extract; the costustoot extract is prepared by a method comprising the following steps: adding water into radix aucklandiae, steam distilling to obtain oil-water mixture, separating oil-water mixture, and collecting water phase to obtain radix aucklandiae extract; the dosage ratio of the costustoot to the water is 1g: 10-20 mL. The giant knotweed extract is prepared by the method comprising the following steps: adding water into rhizoma Polygoni Cuspidati, steam distilling to obtain oil-water mixture, separating the oil-water mixture, and collecting water phase to obtain rhizoma Polygoni Cuspidati extract; the dosage ratio of the costustoot to the water is 1g: 10-20 mL. The wet tissue comprises the composition with the antibacterial effect. Experiments prove that the composition with the antibacterial effect and the wet tissue containing the composition have the remarkable antibacterial effect.
Description
Technical Field
The invention relates to the technical field of daily necessities, in particular to a composition with an antibacterial effect and a wet tissue containing the composition.
Background
The wet tissue is a disposable sanitary product, and the wet tissue is widely applied to various occasions along with the improvement of living standard of people, and especially plays an important role in the occasions inconvenient to use water, for example, the wet tissue can be used for wiping faces and hands, so that the wet tissue is sanitary and convenient.
The wet tissue is generally composed of two parts of a substrate and liquid medicine, wherein the substrate is wet-strength paper or spunlace nonwoven, and the liquid medicine basic formula comprises water, humectant, preservative and nonionic surfactant. The preparation method comprises soaking the base material in the medicinal liquid, taking out the base material, and sealing and packaging to obtain the wet tissue.
The preparation of the liquid medicine in the preparation of the wet tissue is the most critical, the common liquid medicine basic formula only has a cleaning function and does not have an antibacterial function, and if the wet tissue needs to be endowed with the antibacterial function, an antibacterial component needs to be found and added into the liquid medicine to enable the wet tissue to have the antibacterial function.
Disclosure of Invention
The invention aims to overcome the defects in the prior art and provide a composition with an antibacterial effect and a wet tissue containing the composition.
The technical problem to be solved by the invention is realized by the following technical scheme:
a composition with antibacterial effect comprises radix aucklandiae extract and rhizoma Polygoni Cuspidati extract.
Preferably, the costus root extract is prepared by a method comprising the following steps:
adding water into radix aucklandiae, steam distilling to obtain oil-water mixture, separating oil-water mixture, and collecting water phase to obtain radix aucklandiae extract; the dosage ratio of the costustoot to the water is 1g: 10-20 mL.
Further preferably, the using amount ratio of the costustoot to the water is 1g: 12-15 mL.
Preferably, the giant knotweed rhizome extract is prepared by a method comprising the following steps:
adding water into rhizoma Polygoni Cuspidati, steam distilling to obtain oil-water mixture, separating the oil-water mixture, and collecting water phase to obtain rhizoma Polygoni Cuspidati extract; the dosage ratio of the giant knotweed rhizome to the water is 1g: 10-20 mL.
More preferably, the dosage ratio of the giant knotweed rhizome to the water is 1g: 12-15 mL.
Preferably, the weight ratio of the costustoot extract to the giant knotweed extract in the composition is 1-3: 1.
Further preferably, the weight ratio of the costus root extract to the giant knotweed rhizome extract in the composition is 2: 1.
Through a large amount of experimental researches, the inventor discovers that the costustoot extract and the giant knotweed extract prepared by the method have very good antibacterial effect, and especially after the costustoot extract and the giant knotweed extract are mixed according to the weight ratio of 1-3: 1, the antibacterial effect is more obvious, and a synergistic antibacterial effect can be generated.
In addition, the costustoot extract and the giant knotweed rhizome extract are water-soluble components prepared by a steam distillation method, and have good solubility when added into wet tissue liquid medicine.
A wet tissue, which comprises the composition with the antibacterial effect.
Preferably, the wet tissue takes spunlace non-woven fabrics as a base material, the spunlace non-woven fabrics are placed in the liquid medicine for soaking for 1-3 hours, and the spunlace non-woven fabrics are taken out to obtain the wet tissue with the antibacterial effect;
the liquid medicine comprises the following components in parts by weight:
1-3 parts of dodecyl glucoside; 5-10 parts of glycerol; 80-100 parts of the composition with the antibacterial effect.
Further preferably, the liquid medicine comprises the following components in parts by weight:
2 parts of dodecyl glucoside; 8 parts of glycerol; 90 parts of the composition with the antibacterial effect.
Because the composition with the antibacterial effect has a very good antibacterial effect, when the composition is added into wet tissues, the wet tissues can have the antibacterial effect.
Has the advantages that: the invention provides a composition with a brand-new composition and an antibacterial effect, wherein the antibacterial composition is a pure natural component, is safe and nontoxic to use and has an obvious antibacterial effect; the wet tissue has remarkable antibacterial effect due to the composition with antibacterial effect.
Detailed Description
The present invention is further explained below with reference to specific examples, which are not intended to limit the present invention in any way.
EXAMPLE 1 preparation of a composition having antibacterial action
The composition with the antibacterial effect comprises an elecampane extract and a polygonum cuspidatum extract, wherein the weight ratio of the elecampane extract to the polygonum cuspidatum extract is 2: 1;
the costustoot extract is prepared by a method comprising the following steps:
adding water into radix aucklandiae, steam distilling to obtain oil-water mixture, separating oil-water mixture, and collecting water phase to obtain radix aucklandiae extract; the dosage ratio of the costustoot to the water is 1g to 15 mL;
the giant knotweed extract is prepared by the method comprising the following steps:
adding water into rhizoma Polygoni Cuspidati, steam distilling to obtain oil-water mixture, separating the oil-water mixture, and collecting water phase to obtain rhizoma Polygoni Cuspidati extract; the dosage ratio of the giant knotweed rhizome to the water is 1g:15 mL.
EXAMPLE 2 preparation of a composition having antibacterial action
The composition with the antibacterial effect comprises an elecampane extract and a polygonum cuspidatum extract, wherein the weight ratio of the elecampane extract to the polygonum cuspidatum extract is 3: 1;
the costustoot extract is prepared by a method comprising the following steps:
adding water into radix aucklandiae, steam distilling to obtain oil-water mixture, separating oil-water mixture, and collecting water phase to obtain radix aucklandiae extract; the dosage ratio of the costustoot to the water is 1g to 12 mL;
adding water into rhizoma Polygoni Cuspidati, steam distilling to obtain oil-water mixture, separating the oil-water mixture, and collecting water phase to obtain rhizoma Polygoni Cuspidati extract; the dosage ratio of the giant knotweed rhizome to the water is 1g to 12 mL.
EXAMPLE 3 preparation of a composition having antibacterial action
The composition with the antibacterial effect comprises an elecampane extract and a polygonum cuspidatum extract, wherein the weight ratio of the elecampane extract to the polygonum cuspidatum extract is 1: 1;
the costustoot extract is prepared by a method comprising the following steps:
adding water into radix aucklandiae, steam distilling to obtain oil-water mixture, separating oil-water mixture, and collecting water phase to obtain radix aucklandiae extract; the dosage ratio of the costustoot to the water is 1g to 20 mL;
adding water into rhizoma Polygoni Cuspidati, steam distilling to obtain oil-water mixture, separating the oil-water mixture, and collecting water phase to obtain rhizoma Polygoni Cuspidati extract; the dosage ratio of the giant knotweed rhizome to the water is 1g to 20 mL.
Example 4 antimicrobial test
0.1mL of a 1X 10 concentration medium was added7The bacterial liquid per mL (the specific strains are shown in Table 1) is evenly smeared by a sterilized L-shaped smearing rod, dried for 15min at room temperature, an oxford cup is placed into a culture dish by using a sterile forceps, then 100 mu L of test drug is added into the oxford cup, the culture dish is placed into an incubator and cultured for 24h at 37 ℃, the diameter of a bacteriostatic circle is measured, and a control group (the drug is ampicillin) is also arranged. The results are shown in Table 1.
The test drugs were: example 1 compositions (aucklandia root extract: polygonum cuspidatum extract =2: 1), aucklandia root extract (prepared according to the method of example 1), polygonum cuspidatum extract (prepared according to the method of example 1) were prepared.
The control group drugs were: ampicillin at a concentration of 0.2 g/mL.
TABLE 1 antibacterial test results (unit mm)
| Staphylococcus aureus | Escherichia coli | Pseudomonas aeruginosa | |
| Radix aucklandiae extract | 19.17±1.23 | 20.22±1.25 | 20.11±1.37 |
| Polygonum cuspidatum extract | 18.42±1.33 | 19.17±1.29 | 20.07±1.24 |
| Example 1 preparation of a composition | 23.28±1.47 | 25.11±1.36 | 25.44±1.46 |
| Ampicillin | 21.21±1.26 | 23.37±1.32 | 22.12±1.41 |
The results of the antibacterial tests in table 1 show that the costustoot extract and the giant knotweed extract have certain antibacterial effect when used alone, but the antibacterial effect is not obvious and is not as good as that of the positive control drug ampicillin; however, after the costus root extract and the giant knotweed rhizome extract are combined, the composition prepared in example 1 is formed by combining the costus root extract and the giant knotweed rhizome extract according to the weight ratio of 2:1, the antibacterial effect of the composition is greater than that of the costus root extract and the giant knotweed rhizome extract which are used independently, the composition has a synergistic antibacterial effect, and the antibacterial effect of the composition is better than that of ampicillin which is a positive control drug.
Example 5 preparation of Wet tissue with antibacterial Effect
And (3) taking the spunlace non-woven fabric as a base material, soaking the spunlace non-woven fabric in the liquid medicine for 2 hours, and taking out the spunlace non-woven fabric to obtain the wet tissue with the antibacterial effect.
The liquid medicine comprises the following components in parts by weight:
2 parts of dodecyl glucoside; 8 parts of glycerol; 90 parts of the composition having an antibacterial action prepared in example 1.
Example 6 preparation of wet tissue having antibacterial effect
And (3) taking the spunlace non-woven fabric as a base material, soaking the spunlace non-woven fabric in the liquid medicine for 3h, and taking out the spunlace non-woven fabric to obtain the wet tissue with the antibacterial effect.
The liquid medicine comprises the following components in parts by weight:
1 part of dodecyl glucoside; 5 parts of glycerol; 100 parts of the composition having an antibacterial action prepared in example 1.
Example 7 preparation of Wet tissue having antibacterial Effect
And (3) taking the spunlace non-woven fabric as a base material, soaking the spunlace non-woven fabric in the liquid medicine for 1h, and taking out the spunlace non-woven fabric to obtain the wet tissue with the antibacterial effect.
The liquid medicine comprises the following components in parts by weight:
3 parts of dodecyl glucoside; 10 parts of glycerol; 80 parts of the composition having an antibacterial action prepared in example 1.
Claims (8)
1. A composition with antibacterial effect comprises radix aucklandiae extract and rhizoma Polygoni Cuspidati extract;
the costustoot extract is prepared by a method comprising the following steps:
adding water into radix aucklandiae, steam distilling to obtain oil-water mixture, separating oil-water mixture, and collecting water phase to obtain radix aucklandiae extract; the dosage ratio of the costustoot to the water is 1g: 10-20 mL;
the giant knotweed extract is prepared by the method comprising the following steps:
adding water into rhizoma Polygoni Cuspidati, steam distilling to obtain oil-water mixture, separating the oil-water mixture, and collecting water phase to obtain rhizoma Polygoni Cuspidati extract; the dosage ratio of the giant knotweed rhizome to the water is 1g: 10-20 mL.
2. The composition with antibacterial effect according to claim 1, wherein the dosage ratio of radix aucklandiae to water is 1g: 12-15 mL.
3. The composition with antibacterial effect according to claim 1, wherein the dosage ratio of rhizoma Polygoni Cuspidati to water is 1g: 12-15 mL.
4. The composition with antibacterial effect according to claim 1, wherein the weight ratio of the elecampane extract to the polygonum cuspidatum extract in the composition is 1-3: 1.
5. The composition with antibacterial effect according to claim 1, wherein the weight ratio of the elecampane extract to the polygonum cuspidatum extract in the composition is 2: 1.
6. A wet wipe characterized by containing the composition having an antibacterial action according to any one of claims 1 to 5.
7. The wet wipe of claim 6, prepared by a process comprising:
taking spunlace non-woven fabrics as a base material, soaking the spunlace non-woven fabrics in the liquid medicine for 1-3 h, and taking out the spunlace non-woven fabrics to obtain the wet tissue with the antibacterial effect;
the liquid medicine comprises the following components in parts by weight:
1-3 parts of dodecyl glucoside; 5-10 parts of glycerol; 80 to 100 parts of the composition having an antibacterial action according to any one of claims 1 to 5.
8. The wet wipe as claimed in claim 7, wherein the liquid medicine comprises the following components in parts by weight:
2 parts of dodecyl glucoside; 8 parts of glycerol; 90 parts of the composition having an antibacterial action according to any one of claims 1 to 5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710887082.XA CN107616937B (en) | 2017-09-23 | 2017-09-23 | Composition with antibacterial effect and wet tissue containing composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710887082.XA CN107616937B (en) | 2017-09-23 | 2017-09-23 | Composition with antibacterial effect and wet tissue containing composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107616937A CN107616937A (en) | 2018-01-23 |
| CN107616937B true CN107616937B (en) | 2021-03-19 |
Family
ID=61090858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710887082.XA Active CN107616937B (en) | 2017-09-23 | 2017-09-23 | Composition with antibacterial effect and wet tissue containing composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107616937B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520032A (en) * | 2013-10-07 | 2014-01-22 | 上海方木精细化工有限公司 | Violet essential oil-containing antibiotic wet pipe and making method thereof |
| CN103893099A (en) * | 2012-12-27 | 2014-07-02 | 南京恒青楼宇设备有限公司青岛分公司 | Wet tissue |
-
2017
- 2017-09-23 CN CN201710887082.XA patent/CN107616937B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103893099A (en) * | 2012-12-27 | 2014-07-02 | 南京恒青楼宇设备有限公司青岛分公司 | Wet tissue |
| CN103520032A (en) * | 2013-10-07 | 2014-01-22 | 上海方木精细化工有限公司 | Violet essential oil-containing antibiotic wet pipe and making method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN107616937A (en) | 2018-01-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5670201B2 (en) | Antiviral agent and antiviral composition against envelope virus belonging to influenza A virus genus | |
| JP6454805B1 (en) | Alcohol preparation and disinfection method using the same | |
| CN111685134A (en) | Mite-removing and bacterium-inhibiting composition containing plant essential oil and application thereof | |
| US20110028546A1 (en) | Novel antimicrobial formulations incorporating alkyl esters of fatty acids and nanoemulsions thereof | |
| JP5889126B2 (en) | Antibacterial composition | |
| TW201139234A (en) | Aqueous composition contained in container | |
| JP5964118B2 (en) | Antibacterial composition | |
| JP5030422B2 (en) | Antibacterial agent and antibacterial composition containing the same | |
| JPWO2017199921A1 (en) | Antibacterial composition, cosmetic composition containing the same and sheet product for skin | |
| CN106942290A (en) | A kind of wormwood bactericidal composition and its application in liquid detergent | |
| CN111297730A (en) | Long-acting harmless, washing-free and non-flammable macromolecular ethanol disinfectant | |
| CN110327222B (en) | Purely natural plant essential oil sterilization and disinfection wet tissue and preparation method thereof | |
| KR102345209B1 (en) | Sanitizer composition has excellent anti-viral effect, sterilization effect and skin moisturizing effect | |
| CN107496304A (en) | A kind of hand cleanser containing ginger composition | |
| CN110477792A (en) | A kind of nonalcoholic wet tissue and preparation method thereof can be used for breathing mask cleaning-sterilizing | |
| JP2009268698A (en) | Antibacterial sheet-like article | |
| CN107616937B (en) | Composition with antibacterial effect and wet tissue containing composition | |
| CN110251580B (en) | Composite antibacterial agent and preparation method and application thereof | |
| CN107535540A (en) | A kind of antiseptic and preparation method thereof | |
| CN111671816A (en) | Plant type no-clean antibacterial disinfectant and preparation method thereof | |
| CN108295099A (en) | A kind of antiseptic and its application | |
| KR20180113255A (en) | Herbal preservative composition for wet tissue | |
| JP2020033279A (en) | Anti-norovirus agent, disinfectant and cleaning agent | |
| JP2002029978A (en) | Urease inhibitor | |
| KR101928211B1 (en) | Composition having inhibitory effect on microorganism and virus including enterovirus 71 causing hand-foot-mouth symptom |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhu Kunfu Inventor after: Guo Dongwei Inventor after: Liu Yaping Inventor after: Lu Weimin Inventor before: Lu Weimin |
|
| CB03 | Change of inventor or designer information | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20210305 Address after: 274300 Fanlou Road South, Shanxian Development Zone, Heze City, Shandong Province Applicant after: SHANDONG ZHUSHI PHARMACEUTICAL GROUP Co.,Ltd. Address before: 523000 Wanjiang Guyong Industrial Zone, Dongguan City, Guangdong Province Applicant before: DONGGUAN BAITIANE PAPER Co.,Ltd. |
|
| TA01 | Transfer of patent application right |