CN107595997A - Alimentation composition and its application containing pufa oils - Google Patents

Alimentation composition and its application containing pufa oils Download PDF

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Publication number
CN107595997A
CN107595997A CN201710933081.4A CN201710933081A CN107595997A CN 107595997 A CN107595997 A CN 107595997A CN 201710933081 A CN201710933081 A CN 201710933081A CN 107595997 A CN107595997 A CN 107595997A
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Prior art keywords
alimentation composition
pufa oils
containing pufa
oil
component
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CN201710933081.4A
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CN107595997B (en
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顾茂健
苏健梅
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Xuan Tai Bio Tech Ltd Shanghai
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Xuan Tai Bio Tech Ltd Shanghai
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Abstract

The invention discloses a kind of alimentation composition containing pufa oils and its application, the alimentation composition containing pufa oils, include the component of following percentage by weight:Pufa oils 50 95%, ginseng extract 1 30%, taurine 1 30%, Guarana extract 1 20%, vitamin E 0.1 10%, lecithin 0.1 8%.The present invention alimentation composition, can be eaten as ordinary food, it is natural and safe, not only have the function that resist oxygen lack, it is antifatigue also have the function that radioresistance, raising memory, strengthen immunity.

Description

Alimentation composition and its application containing pufa oils
Technical field
The present invention relates to a kind of alimentation composition containing polyunsaturated fatty acid, and in particular to it is a kind of can be antifatigue Alimentation composition.
Background technology
Fatigue is a kind of common phenomenon of modern society, and today's society dog-eat-dog, people are usually without the excessive time To consider daily diet arrangement, nervous working and learning make their body consume and lose substantial amounts of nutrition and energy again Amount.
The nutrition required for organism metabolism how is obtained in the diet beyond daily breakfast, lunch and dinner, and promotes waste and nuisance Matter excludes from body, body is in a kind of good metabolism, recurrent stateHere it is one that each of us faces Major issue, the body of unsoundness have abundant energy, just can guarantee that we have the live and work of high quality daily.Oxygen is Human body carries out the key substance of metabolism, is the primary need of human life activity.The oxygen sucked by lung is converted into human body Available blood oxygen, blood carries the energy needed for blood oxygen to whole body input biological oxidation, therefore oxygen is in normal activities Indispensable important substance.When breathing stopping, the vital movement that can only also maintain a few minutes is made full use of even if internal storage oxygen. But the various metabolic activities of general body are not all before internal oxygen is also completely depleted, so that it may obvious obstacle occur. With the improvement of people's living standards, also increasing year by year the demand of various raising anoxia endurance health products, it is resistance to improve anoxic Stress health products have a very important role to the quality of life for improving people.At present, on the market various raising anoxics are resistance to Stress health products species is various, but many health products are harmful in the presence of addition chemicals, long-term use, and toxic side effect It is larger, such as:Capsule or tablet using red scape as main component, it is long-term use of, can produce bad allergy, palpitaition, stomach, headache and The side effects such as nausea;So far, how to prepare one kind and can improve high altitude anoxia tolerance, added without chemicals, long-term clothes With harmless, and the small natural compound formulation of toxic side effect turns into the current technical issues that need to address.
The content of the invention
It is an object of the invention to provide a kind of alimentation composition containing pufa oils and its application, to overcome The defects of prior art is present, meet the needs of people.
Alimentation composition of the present invention containing pufa oils, include the group of following percentage by weight Point:
The percentage sum of each component is 100%
Preferably, the alimentation composition of the present invention containing pufa oils, including following weight percent The component of ratio:
The percentage sum of each component is 100%;
The pufa oils are sunflower oil, imperial rice bran oil, peanut oil, olive oil, linseed oil or other phases Like structure pufa oils in one kind or its combination;
Imperial rice bran oil is the vegetable oil that refined refinement forms, holy life to be spent using Gansu by poppy seed after inactivation The product of thing development corporation, Ltd.;
The linseed oil can use the product of Hebei Xin Qi Dian Biotechnology Co., Ltd.;
Described ginseng extract can use the product of the gloomy bio tech ltd in Shanghai;
Described Guarana extract can use the product of the upper corporate agent of Haicheng one;
The preparation method of the described alimentation composition containing pufa oils is simple physical mixed, will be each Individual component mixing.
Animal experiment proves, the alimentation composition containing pufa oils, for alleviating physical fatigue, With obvious action, can be used for preparing the preparation for alleviating physical fatigue, described preparation includes tablet and capsule.
Physical fatigue caused by described physical fatigue, including anoxic or cerebral ischemia ischemic;
The present invention composition, can by orally be used for need crowd, dosage be generally 2~6g/60 kg body weights/ My god;
The beneficial effects of the invention are as follows:
The described alimentation composition containing pufa oils, can eat as ordinary food, natural and peace Quan Xinggao, not only have the function that resist oxygen lack, it is antifatigue also have the function that radioresistance, improve memory, strengthen immunity.
Embodiment
Embodiment 1
Prescription:(percentage by weight)
Preparation method:
Each component is mixed, stirred, filling soft capsule, you can obtain the described nutrient combination containing imperial rice bran oil The capsule of thing.
Embodiment 2
Preparation method is the same as embodiment 1.
Embodiment 3
Step embodiment 1.
Embodiment 4
Anti anoxia is tested:
Material:KM mouse, SPF levels, Male adult mice, 18~22g are qualified from experimental animal portion of Fudan University Card number is SCXK Shanghai 2002-002;Rhodiola rosea capsules:Beijing Tongrentang Health Pharmaceutical Co., Ltd., the strong word of lot number state food G20100243, specification 400mg/ grains;
Oxygen deficit tolerance is tested
Experimental method:Mouse is divided into 5 groups, every group 10, embodiment 1, embodiment 2, embodiment 3 set 3 dosage respectively Group was through gavage successive administration 30 days, and once a day, gavage volume is 0.1ml/10g body weight, and negative control group gives equivalent distillation Water, 500mg/ kilograms of positive controls oral Rhodiola rosea capsules, after last gavage 1h, each mouse, which is respectively put into, fills 5g sodium stones In the 250ml port grinding bottles of ash (one every bottle), sealing, stopped with breathing as dead indication, record the mouse survival time.As a result use SPSS statistical softwares carry out t inspections, are shown in Table 1.
Influence (n=10, x ± S) of the table 1 to the mouse oxygen deficit tolerance time-to-live
Compared with negative control group, * P < 0.05;* P < 0.01
As a result show, inventive samples can significantly improve the mouse survival time, there is obvious resist oxygen lack effect;Embodiment There is significant difference the time-to-live of 2 groups of raising mouse.
Acute cerebral hypoxia is tested
Experimental method:Mouse is divided into 5 groups, every group 10, embodiment 1 (200,500,1000mg/kg), embodiment 2 (200,500,1000mg/kg), embodiment 3 (200,500,1000mg/kg), it is once a day, cloudy through gavage successive administration 30 days Property control group gives equivalent distilled water, the oral Rhodiola rosea capsules 500mg/kg of positive controls.After last 1h, each group animal is certainly Neck is regularly dehisced to dehiscing to show, using the time of panting as index after record mouse broken end by only breaking end.As a result use SPSS statistical softwares carry out t inspections, are shown in Table 2.
Influence (n=10, x ± S) of the table 2 to the chmice acute cerebral anoxia time
Embodiment 1,2 and 3 can extend breathing time, * P < 0.01, have statistical significance compared with control group, can Show that product of the present invention has protective effect to cerebral ischemia ischemic.Function of physical fatigue alleviation is tested
Experimental method:Mouse is divided into 5 groups, every group 10, embodiment 1 (200,500,1000mg/kg), embodiment 2 (200,500,1000mg/kg), embodiment 3 (200,500,1000mg/kg), it is once a day, cloudy through gavage successive administration 30 days Property control group gives equivalent distilled water, the oral Rhodiola rosea capsules 500mg/kg of positive controls.
Swimming with a load attached to the body is tested:Last orally gives after tested material 30 minutes, carries out swimming test (water temperature is 25 ± 0.5 DEG C), Record mouse enters time when water to power exhausts dead.Experimental data uses SPSS software statistics, the results are shown in Table 3;Hepatic glycogen content Determination experiment:Last orally gives after tested material 30 minutes, puts to death the measure that animal takes liver to carry out liver glycogen content, experimental data Using SPSS software statistics, 4 are the results are shown in Table.
Serum lactic acid content determination experiment:Last is taken a blood sample for 30 minutes after orally giving tested material, is not then born a heavy burden in 30 DEG C of temperature Take a blood sample after water went swimming 10min, taken a blood sample again after rest 20min immediately, three time points were taken a blood sample and carry out Serum lactic acid content measure; Experimental data uses SPSS software statistics, the results are shown in Table 5.
Serum urea assay is tested:Last orally gives after tested material 30 minutes, does not bear a heavy burden in 30 DEG C of water middle reaches of temperature Swim 90min, is taken a blood sample again after rest 60min, and the clear urea content measure of the separation laggard promoting circulation of blood of serum, experimental data uses SPSS softwares Statistics, the results are shown in Table 6.
The swimming time (x ± SD) of each group mouse of table 3
* p < 0.005
Known by upper table:The middle and high dosage group of embodiment can significantly improve the swimming time of mouse, slightly better than positive control Rhodiola rosea capsules;
The liver glycogen content (x ± SD) of each group mouse of table 4
* p < 0.005
Known by upper table:The middle and high dosage group of embodiment can significantly improve the liver glycogen amount of mouse, and slightly right better than positive According to Rhodiola rosea capsules;
Before the swimming of each group mouse of table 5, being rested 20 minutes immediately, after swimming after swimming determines Serum lactic acid content (x ± SD)
* p < 0.005
Known by upper table:The middle and high dosage group of sample can significantly reduce the Serum lactic acid content of mouse, and effect is slightly better than the positive Control;
The serum urea content (x ± SD) of each group mouse of table 6
* p < 0.005
Known by upper table:The middle and high dosage group of embodiment can significantly reduce the serum uric acid of mouse, and effect is slightly better than Positive control Rhodiola rosea capsules;Result above shows:The alimentation composition of the present invention has the function that to alleviate physical fatigue.

Claims (8)

1. the alimentation composition containing pufa oils, it is characterised in that include the component of following percentage by weight:
The percentage sum of each component is 100%.
2. the alimentation composition according to claim 1 containing pufa oils, it is characterised in that including as follows The component of percentage by weight:
The percentage sum of each component is 100%.
3. the alimentation composition according to claim 1 or 2 containing pufa oils, it is characterised in that described Pufa oils be sunflower oil, imperial rice bran oil, peanut oil, olive oil, linseed oil or other similar structures it is more not One kind or its combination in unsaturated fatty acid oil.
4. the application of the alimentation composition containing pufa oils according to claim 1,2 or 3, its feature exist In for preparing the preparation of alleviation physical fatigue.
5. application according to claim 4, it is characterised in that described preparation includes tablet and capsule.
6. application according to claim 4, it is characterised in that described physical fatigue, including anoxic or cerebral ischemia lack Physical fatigue caused by blood.
7. application according to claim 4, it is characterised in that by being orally used for the crowd needed, dosage is 2~6g/ 60 kg body weights/day.
8. the alimentation composition containing pufa oils described in claim 1,2 or 3 is preparing alleviation physical fatigue Preparation in application.
CN201710933081.4A 2017-10-10 2017-10-10 Nutritional composition containing polyunsaturated fatty acid oil and its application Active CN107595997B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101574140A (en) * 2008-11-27 2009-11-11 厦门金日制药有限公司 Drink composition with human immunity strengthening and anti-fatigue functions
CN105685960A (en) * 2016-02-16 2016-06-22 江苏隆力奇生物科技股份有限公司 Composition with refreshing and anti-fatigue effects, method for preparing composition and application thereof
CN107156846A (en) * 2017-06-22 2017-09-15 利康行(北京)生物科技有限公司 Complex health care product that is a kind of antifatigue and improving anoxia endurance

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101574140A (en) * 2008-11-27 2009-11-11 厦门金日制药有限公司 Drink composition with human immunity strengthening and anti-fatigue functions
CN105685960A (en) * 2016-02-16 2016-06-22 江苏隆力奇生物科技股份有限公司 Composition with refreshing and anti-fatigue effects, method for preparing composition and application thereof
CN107156846A (en) * 2017-06-22 2017-09-15 利康行(北京)生物科技有限公司 Complex health care product that is a kind of antifatigue and improving anoxia endurance

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