CN103251927A - Composition containing bilberry extract - Google Patents
Composition containing bilberry extract Download PDFInfo
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- CN103251927A CN103251927A CN2013101254477A CN201310125447A CN103251927A CN 103251927 A CN103251927 A CN 103251927A CN 2013101254477 A CN2013101254477 A CN 2013101254477A CN 201310125447 A CN201310125447 A CN 201310125447A CN 103251927 A CN103251927 A CN 103251927A
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- pericarpium citri
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Abstract
The invention discloses a composition containing a bilberry extract. The composition comprises, by weight, 25 parts of the bilberry extract, 20 to 30 parts of citrus bioflavonoids, 20 to 30 parts of taurine, 15 to 20 parts of eyebright, 12 to 18 parts of a chrysanthemum extract, 10 to 15 parts of xanthophyll, 10 to 15 parts of quercetin, 3 to 7 parts of L-acetylcysteine, 2 to 4 parts of L-glutathione, 2 to 3 parts of zeaxanthin, 1 to 1.5 parts of astaxanthin, 1.5 to 2 parts of beta-carotene, 120 to 180 parts of vitamin C, 40 to 65 parts of vitamin E, 5 to 10 parts of vitamin B2, 5 to 10 parts of vitamin B6, 15 to 20 parts of calcium carbonate and L-calcium ascorbate, 8 to 12 parts of zinc sulfate, 0.8 to 1.2 parts of copper gluconate, 0.02 to 0.03 part of chromium picolinate and 0.01 to 0.02 part of chelated selenium. After oral administration of the composition, nyctalopia and eyesight of people can be improved.
Description
Technical field
The present invention relates to the medicines and health protection technical field, relate in particular to a kind of compositions that contains Pericarpium Citri tangerinae extract.
Background technology
Pericarpium Citri tangerinae is a kind of wild acinus, also claims blue berry.Pericarpium Citri tangerinae is nutritious because of it, and the effect uniqueness is subjected to the favor of American-European consumer deeply, and ripe Pericarpium Citri tangerinae extract is rich in flavonoid pigment and antioxidant anthocyanidin.Often taking Pericarpium Citri tangerinae extract can promote vision to improve.
Contain anthocyanin, flavonoid, unknown enzyme and anti-cancer active matter in the Pericarpium Citri tangerinae, take for a long time can keep vision good, strengthen cardiovascular and cerebrovascular vessel and arteries, make capillary permeability normalization.In addition, Pericarpium Citri tangerinae also can be improved nyctalopia.Anthocyanidin in the Pericarpium Citri tangerinae extract is a kind of biological flavone, and the tool antioxidant action can assist to remove poisonous chemical substance in the retina.
Yet do not see on the market the relevant medicines and health protection compositions that contains Pericarpium Citri tangerinae extract is arranged.
Summary of the invention
Main purpose of the present invention is to provide a kind of compositions that contains Pericarpium Citri tangerinae extract, improves nyctalopia by taking said composition, reaching, to reach the effect that improves vision.
The present invention proposes a kind of compositions of Pericarpium Citri tangerinae extract, by weight, comprises following component:
Pericarpium Citri tangerinae extract is 25 parts; the citrus biological flavone is 20-30 part; taurine is 20-30 part; Herba Euphrasiae Regelii is 15-20 part; Flos Chrysanthemi extract is 12-18 part; phylloxanthin is 10-15 part; Quercetin is 10-15 part; the L-acetylcysteine is 3-7 part; the L-glutathion is 2-4 part; cryptoxanthin is 2-3 part; astaxanthin is 1-1.5 part; beta-carotene is 1.5-2 part; vitamin C is 120-180 part; vitamin E is 40-65 part; vitamin B2 is 5-10 part; vitamin B6 is 5-10 part; calcium carbonate and L-calcium ascorbate are 15-20 part; zinc sulfate is 8-12 part; copper gluconate is 0.8-1.2 part; chromium picolinate is 0.02-0.03 part; chelated selenium is 0.01-0.02 part.
Preferably, described Pericarpium Citri tangerinae extract is 25 parts; the citrus biological flavone is 22-27 part; taurine is 22-27 part; Herba Euphrasiae Regelii is 17-18 part; Flos Chrysanthemi extract is 14-16 part; phylloxanthin is 12-13 part; Quercetin is 12-13 part; the L-acetylcysteine is 4-6 part; the L-glutathion is 3 parts; cryptoxanthin is 3 parts; astaxanthin is 1.2-1.3 part; beta-carotene is 1.7-2 part; vitamin C is 140-160 part; vitamin E is 50-60 part; vitamin B2 is 7-8 part; vitamin B6 is 7-8 part; calcium carbonate and L-calcium ascorbate are 16-18 part; zinc sulfate is 9-11 part; copper gluconate is 1-1.2 part; chromium picolinate is 0.025-0.03 part; chelated selenium is 0.015-0.02 part.
Preferably, described Pericarpium Citri tangerinae extract is that 25 parts, citrus biological flavone are that 25 parts, taurine are 25 parts; Herba Euphrasiae Regelii is 17.5 parts, Flos Chrysanthemi extract is 15 parts, phylloxanthin is 12.5 parts, Quercetin is 12.5 parts, the L-acetylcysteine is 5 parts, the L-glutathion is 3 parts, cryptoxanthin is 2.5 parts, astaxanthin is 1.25 parts, beta-carotene is 1.875 parts, vitamin C is 150 parts, vitamin E is 55 parts, vitamin B2 is 7.5 parts, vitamin B6 is 7.5 parts, calcium carbonate and L-calcium ascorbate are 17 parts, zinc sulfate is 10 parts, copper gluconate is 1 part, chromium picolinate is 0.025 part, chelated selenium is 0.015 part.
A kind of compositions that comprises Pericarpium Citri tangerinae extract provided by the invention, because containing, said composition has anticancer, as can to assist to remove noxious substance in retina Pericarpium Citri tangerinae extract, oral described compositions provided by the present invention can reach and improve nyctalopia, improves the effect of vision.
The specific embodiment
Further specify the present invention below by embodiment and Comparative Examples.
Embodiment 1: the preparation of the capsule of the compositions that contains Pericarpium Citri tangerinae extract of the present invention
With described Pericarpium Citri tangerinae extract, the citrus biological flavone, taurine, Herba Euphrasiae Regelii, Flos Chrysanthemi extract, phylloxanthin, Quercetin, the L-acetylcysteine, the L-glutathion, cryptoxanthin, astaxanthin, beta-carotene, vitamin C, vitamin E, vitamin B2, vitamin B6, calcium carbonate and L-calcium ascorbate, zinc sulfate, copper gluconate, chromium picolinate, chelated selenium is ground into fine powder respectively, powder material after will pulverizing is then crossed the 80-100 mesh sieve respectively, take by weighing each component after sieving respectively according to the content of table 1 appointment then, and each component is mixed first mixture that forms fine-powdered; Add an amount of adjuvant at this first mixture, and it is fully mixed, form uniform second mixture; This second mixture is filled in the capsulae vacuus, and first mixture with a certain amount of of guaranteeing to pack in each capsulae vacuus, seal then, polish.
Embodiment 2: the operation by each component repetition embodiment 1 that specifies content in the following table 1 makes the capsule that contains the Pericarpium Citri tangerinae extract compositions of the present invention.
Embodiment 3: the preparation that contains the powder of Pericarpium Citri tangerinae extract compositions of the present invention
With described Pericarpium Citri tangerinae extract, the citrus biological flavone, taurine, Herba Euphrasiae Regelii, Flos Chrysanthemi extract, phylloxanthin, Quercetin, the L-acetylcysteine, the L-glutathion, cryptoxanthin, astaxanthin, beta-carotene, vitamin C, vitamin E, vitamin B2, vitamin B6, calcium carbonate and L-calcium ascorbate, zinc sulfate, copper gluconate, chromium picolinate, chelated selenium is ground into fine powder respectively, powder material after will pulverizing is then crossed the 80-100 mesh sieve respectively, take by weighing each component after sieving respectively according to the content of table 1 appointment then, and each component is mixed first mixture that forms fine-powdered; Add an amount of adjuvant at this first mixture, and it is fully mixed, form uniform second mixture; This second mixture is filled in the compound membrane bag, and described first mixture with a certain amount of of guaranteeing to pack in each compound membrane bag, seal then, polish.
Embodiment 4: the operation by each component repetition embodiment 3 that specifies content in the following table 1 makes the powder that contains the compositions of Pericarpium Citri tangerinae extract of the present invention.
Embodiment: 5: the preparation of the tablet of the compositions that contains Pericarpium Citri tangerinae extract of the present invention
With described Pericarpium Citri tangerinae extract, the citrus biological flavone, taurine, Herba Euphrasiae Regelii, Flos Chrysanthemi extract, phylloxanthin, Quercetin, the L-acetylcysteine, the L-glutathion, cryptoxanthin, astaxanthin, beta-carotene, vitamin C, vitamin E, vitamin B2, vitamin B6, calcium carbonate and L-calcium ascorbate, zinc sulfate, copper gluconate, chromium picolinate, chelated selenium is ground into fine powder respectively, powder material after will pulverizing is then crossed the 80-100 mesh sieve respectively, take by weighing each component after sieving respectively according to the content of table 1 appointment then, and each component is mixed first mixture that forms fine-powdered; Add an amount of adjuvant at this first mixture, and it is fully mixed, form uniform second mixture; This second mixture is suppressed in flakes, and contained in guaranteeing every with a certain amount of described first mixture.
Embodiment 6: the operation by each component repetition embodiment 5 that specifies content in the following table 1 makes the tablet that contains the compositions of Pericarpium Citri tangerinae extract of the present invention.
Experimental example 1: the clinical observation that contains the combination treatment nyctalopia of Pericarpium Citri tangerinae extract of the present invention
1, physical data
Accept out-patient's totally 48 examples for medical treatment, male 30 examples wherein, women 18 examples, M-F 4:3.Age 20-30 year 5 examples, 31-40 year 12 examples, 41-50 year 13 examples, 51-70 year 18 examples.Wherein, professional cadre 12 people, teacher 4 people, workman 10 people, student 4 people, driver 5 people, retired person 13 examples.
2, diagnostic criteria:
Slight nyctalopia: can see thing daytime, sees that thing is unclear night;
The moderate nyctalopia: the visual field is constriction slowly, sees that thing is unclear night;
The severe nyctalopia: form tubular visual field, the thing of middle body before only seeing be cannot see peripheral thing;
3; Therapeutic Method: oral 2 times of every day; each effectively dose is the 590*2 milligram; two weeks is a course for the treatment of; be used in conjunction 3-4 the course for the treatment of; wherein said effective dose refers to the content of active drug, and wherein said active drug comprises following component: Pericarpium Citri tangerinae extract; the citrus biological flavone; taurine; Herba Euphrasiae Regelii; Flos Chrysanthemi extract; phylloxanthin; Quercetin; the L-acetylcysteine; the L-glutathion; cryptoxanthin; astaxanthin; beta-carotene; vitamin C; vitamin E; vitamin B2; vitamin B6; calcium carbonate and L-calcium ascorbate; zinc sulfate; copper gluconate; chromium picolinate; chelated selenium.
4, efficacy assessment standard:
Produce effects: see that thing is obviously clear night, the visual field is open gradually
Take a turn for the better: can see thing night clearly, and it is normal that recover in the visual field
Invalid: symptom does not have improvement.
5, therapeutic effect
The above-mentioned nyctalopia patient of combination treatment who adopts embodiments of the invention to make, wherein the compositions of every embodiment correspondence is used for the treatment of 8 people, and its therapeutic effect is referring to table 2.
By following table 2 data as can be known, the compositions that contains Pericarpium Citri tangerinae extract provided by the present invention has better curative effect to the nyctalopia patient, can make the patient reach the effect that improves vision.
More than the Pericarpium Citri tangerinae extract that adopts in the Pericarpium Citri tangerinae extract compositions provided by the present invention be the powder of outward appearance darkviolet, wherein, contained anthocyanidin 〉=25.5g/100g; Moisture≤5%; Ash≤5%; Total plate count≤30000cfu/g; Coliform≤90MPN/100g; Mycete≤25cfu/g; Yeast≤25cfu/g; Pathogenic bacterium do not detect.
Should be understood that the present invention can summarize with other the concrete form without prejudice to spirit of the present invention or principal character.Therefore, no matter from which point, the above embodiment of the present invention can only be thought can not limit the present invention to explanation of the present invention, claims have been pointed out scope of the present invention, and scope of the present invention is not pointed out in above-mentioned explanation, therefore in the implication suitable with claims of the present invention and any change in the scope, all should think to be included in the scope of claims.
Table 1
The observation of curative effect of table 2 nyctalopia after treatment:
Claims (3)
1. the compositions of a Pericarpium Citri tangerinae extract by weight, comprises following component:
Pericarpium Citri tangerinae extract is 25 parts; the citrus biological flavone is 20-30 part; taurine is 20-30 part; Herba Euphrasiae Regelii is 15-20 part; Flos Chrysanthemi extract is 12-18 part; phylloxanthin is 10-15 part; Quercetin is 10-15 part; the L-acetylcysteine is 3-7 part; the L-glutathion is 2-4 part; cryptoxanthin is 2-3 part; astaxanthin is 1-1.5 part; beta-carotene is 1.5-2 part; vitamin C is 120-180 part; vitamin E is 40-65 part; vitamin B2 is 5-10 part; vitamin B6 is 5-10 part; calcium carbonate and L-calcium ascorbate are 15-20 part; zinc sulfate is 8-12 part; copper gluconate is 0.8-1.2 part; chromium picolinate is 0.02-0.03 part; chelated selenium is 0.01-0.02 part.
2. the compositions of Pericarpium Citri tangerinae extract according to claim 1 is characterized in that,
Described Pericarpium Citri tangerinae extract is 25 parts; the citrus biological flavone is 22-27 part; taurine is 22-27 part; Herba Euphrasiae Regelii is 17-18 part; Flos Chrysanthemi extract is 14-16 part; phylloxanthin is 12-13 part; Quercetin is 12-13 part; the L-acetylcysteine is 4-6 part; the L-glutathion is 3-4 part; cryptoxanthin is 2-3 part; astaxanthin is 1.2-1.3 part; beta-carotene is 1.7-2 part; vitamin C is 140-160 part; vitamin E is 50-60 part; vitamin B2 is 7-8 part; vitamin B6 is 7-8 part; calcium carbonate and L-calcium ascorbate are 16-18 part; zinc sulfate is 9-11 part; copper gluconate is 1-1.2 part; chromium picolinate is 0.025-0.03 part; chelated selenium is 0.015-0.02 part.
3. the compositions of Pericarpium Citri tangerinae extract according to claim 2 is characterized in that,
Described Pericarpium Citri tangerinae extract is 25 parts; the citrus biological flavone is 25 parts; taurine is 25 parts; Herba Euphrasiae Regelii is 17.5 parts; Flos Chrysanthemi extract is 15 parts; phylloxanthin is 12.5 parts; Quercetin is 12.5 parts; the L-acetylcysteine is 5 parts; the L-glutathion is 3 parts; cryptoxanthin is 2.5 parts; astaxanthin is 1.25 parts; beta-carotene is 1.875 parts; vitamin C is 150 parts; vitamin E is 55 parts; vitamin B2 is 7.5 parts; vitamin B6 is 7.5 parts; calcium carbonate and L-calcium ascorbate are 17 parts; zinc sulfate is 10 parts; copper gluconate is 1 part; chromium picolinate is 0.025 part; chelated selenium is 0.015 part.
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CN2013101254477A CN103251927A (en) | 2013-04-11 | 2013-04-11 | Composition containing bilberry extract |
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CN2013101254477A CN103251927A (en) | 2013-04-11 | 2013-04-11 | Composition containing bilberry extract |
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Cited By (9)
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CN104115909A (en) * | 2014-08-19 | 2014-10-29 | 天津市尖峰天然产物研究开发有限公司 | Fruit and vegetable powder health care biscuits for protecting eyes and improving eyesight |
CN104523483A (en) * | 2014-12-06 | 2015-04-22 | 广州一生美网络科技有限公司 | Antioxidant, anti-aging and anti-radiation eye pad composition and preparation method thereof |
WO2015163165A1 (en) * | 2014-04-22 | 2015-10-29 | 興人ライフサイエンス株式会社 | Glutathione-containing antioxidant composition |
CN105535930A (en) * | 2015-12-21 | 2016-05-04 | 天津中津药业股份有限公司 | Health-care medicine composition |
CN106617055A (en) * | 2016-12-13 | 2017-05-10 | 深圳万稞生物科技有限公司 | Eye-protecting healthcare food for relieving degenerative eye diseases and preparation method thereof |
CN107158028A (en) * | 2017-05-25 | 2017-09-15 | 北京吴云生中医药研究院 | A kind of bright eye health promoting liquid |
CN107307418A (en) * | 2017-07-01 | 2017-11-03 | 山东健康源生物工程有限公司 | It is a kind of to be used to alleviate cowberry vitamin A soft capsule of visual fatigue and preparation method thereof |
CN108902974A (en) * | 2018-07-20 | 2018-11-30 | 深圳市博奥生物科技有限公司 | A kind of cowberry lutein capsule and preparation method thereof |
CN109068712A (en) * | 2016-05-13 | 2018-12-21 | 格力高营养食品株式会社 | Carotenoid balances improver in blood |
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Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2015163165A1 (en) * | 2014-04-22 | 2015-10-29 | 興人ライフサイエンス株式会社 | Glutathione-containing antioxidant composition |
CN104115909A (en) * | 2014-08-19 | 2014-10-29 | 天津市尖峰天然产物研究开发有限公司 | Fruit and vegetable powder health care biscuits for protecting eyes and improving eyesight |
CN104523483A (en) * | 2014-12-06 | 2015-04-22 | 广州一生美网络科技有限公司 | Antioxidant, anti-aging and anti-radiation eye pad composition and preparation method thereof |
CN105535930A (en) * | 2015-12-21 | 2016-05-04 | 天津中津药业股份有限公司 | Health-care medicine composition |
CN109068712A (en) * | 2016-05-13 | 2018-12-21 | 格力高营养食品株式会社 | Carotenoid balances improver in blood |
EP3456208A4 (en) * | 2016-05-13 | 2020-01-08 | Glico Nutrition Co., Ltd. | Agent for improving carotenoid balance in blood |
CN106617055A (en) * | 2016-12-13 | 2017-05-10 | 深圳万稞生物科技有限公司 | Eye-protecting healthcare food for relieving degenerative eye diseases and preparation method thereof |
CN107158028A (en) * | 2017-05-25 | 2017-09-15 | 北京吴云生中医药研究院 | A kind of bright eye health promoting liquid |
CN107307418A (en) * | 2017-07-01 | 2017-11-03 | 山东健康源生物工程有限公司 | It is a kind of to be used to alleviate cowberry vitamin A soft capsule of visual fatigue and preparation method thereof |
CN107307418B (en) * | 2017-07-01 | 2020-11-20 | 山东健康源生物工程有限公司 | Blueberry vitamin A soft capsule for relieving visual fatigue and preparation method thereof |
CN108902974A (en) * | 2018-07-20 | 2018-11-30 | 深圳市博奥生物科技有限公司 | A kind of cowberry lutein capsule and preparation method thereof |
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