CN107582908A - A kind of Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom - Google Patents
A kind of Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom Download PDFInfo
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- CN107582908A CN107582908A CN201710756371.6A CN201710756371A CN107582908A CN 107582908 A CN107582908 A CN 107582908A CN 201710756371 A CN201710756371 A CN 201710756371A CN 107582908 A CN107582908 A CN 107582908A
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Abstract
The invention discloses a kind of Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom, including it is 8 ~ 12 parts of the root of kudzu vine in parts by weight, 5 ~ 10 parts of radish seed, 6 ~ 11 parts of coix seed, 6 ~ 9 parts of the tuber of pinellia, 9 ~ 15 parts of stir-baked RADIX PAEONIAE ALBA, 4 ~ 8 parts of Poria cocos, 9 ~ 15 parts of lotus seeds, 6 ~ 10 parts of Divine Comedy, 9 ~ 15 parts of nutmeg, windproof 5 ~ 8 parts.The beneficial effects of the invention are as follows：The present invention is based on the understanding and principle of reatment to chronic diarrhea symptom mechanism, and using directly oral method, tonification and purgation in combination, has tonifying Qi dampness elimination, the effect of function of spleen and stomach regulating altogether, and evident in efficacy, quality is easily controlled, and stability is good, has no adverse reaction substantially.
Description
Technical field
The present invention relates to the field of Chinese medicines, is a kind of Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom specifically.
Background technology
Diarrhoea refers to that defecation frequency increases, and excrement is thin, or even gushes watery object plane such as and say.Clinically common dry enteron aisle disease
Disease.
At present, when people suffer from chronic diarrhea disease, in the city that medical condition is more flourishing, people are controlled to hospital
Treat, typically treated using Western medicine or have an injection, and in small towns, particularly some are away from small towns, outlying village,
When people suffer from the disease of chronic diarrhea, because family income is low, living in penury, locality lacks medical condition, if it is desired to controls
The city that disease needs to spend many travelling expenses to go medical condition more flourishing is gone to seek medical advice, in addition the medical expense and medical expenses of hospital
Costliness, people often do not go sick treatment, give free rein to fully recover, therefore some patients delay therapic opportunity.
The content of the invention
It is an object of the invention to provide a kind of evident in efficacy, quick, stability it is good be advantageous to alleviate chronic diarrhea
The Chinese medicine preparation of symptom.
The present invention is achieved through the following technical solutions：A kind of Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom, including
5 ~ 8 parts of the root of kudzu vine in parts by weight, 5 ~ 8 parts of radish seed, 6 ~ 9 parts of coix seed, 6 ~ 9 parts of the tuber of pinellia, 9 ~ 15 parts of stir-baked RADIX PAEONIAE ALBA, Poria cocos 4 ~ 8
It is part, 9 ~ 15 parts of lotus seeds, 6 ~ 10 parts of Divine Comedy, 9 ~ 15 parts of nutmeg, windproof 5 ~ 8 parts.
A kind of bulk drug pharmacology for being used to treat the Chinese medicine composition of chronic diarrhea of the present invention：
The root of kudzu vine：It is cool in nature, it is sweet, pungent.Returns spleen warp, stomach.Expelling pathogenic factors from muscles and skin is brought down a fever, promoted the production of body fluid, promoting eruption, Shengyang Zhixie.Classify under category diaphoretic medicine
Cold-pungent and diaphoretic drugs.
Radish seed：It is mild-natured, it is acrid flavour, sweet.Returns spleen warp, stomach, lung channel.Lower gas, eliminating the phlegm, promoting digestion and removing indigestion.Belong to digestants.
Coix seed：It is cool in nature, it is sweet, light.Returns spleen warp, stomach, lung channel.Invigorating spleen to remove dampness, remove numbness antidiarrheal, clearing away heat and eliminating pus.Category profit
The stranguria-relieving diuretic of water excreting dampness medicine subordinate classification.
The tuber of pinellia：Warm-natured, acrid flavour is poisonous.Returns spleen warp, stomach, lung channel.Eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Category is clear
The heat-clearing and damp-drying drug of medicine of a warm nature subordinate classification.
Stir-baked RADIX PAEONIAE ALBA：Cold nature, bitter, acid.Return liver warp, the spleen channel.Smooth liver and relieve pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Belong to qi-restoratives medicine
The antianaemics of subordinate's classification.
Poria cocos：It is mild-natured, it is sweet, light.Thoughts of returning home warp, lung channel, the spleen channel, kidney channel.Clearing damp and promoting diuresis, invigorating the spleen calming heart.Belong to clearing damp and promoting diuresis
The edema-alleviating diuretic of medicine subordinate classification.
Lotus seeds：It is mild-natured, it is sweet, puckery.Returns spleen warp, kidney channel, the heart channel of Hang-Shaoyin.Tonifying spleen and stopping diarrhea, supplementing the kidney to control the nocturnal, mental-tranquilization.Belong to inducing astrigency
The astringent sperm contracting urine stop-band medicine of medicine subordinate classification.
Divine Comedy：It is warm-natured, it is sweet, pungent.Returns spleen warp, stomach.Promoting digestion and removing indigestion, strengthening the spleen and stomach.Belong to digestants.
Nutmeg：It is warm-natured, acrid flavour.Slightly poisonous returns large intestine channel, stomach, the spleen channel.Middle benefit gas promoting the circulation of qi, relieving diarrhea with astringents.Belong to astringent medicinal
The lung-intestine astringent medicinal of lower classification.
It is windproof：It is warm-natured, it is sweet, pungent.Return bladder warp, Liver Channel, the spleen channel.Deliver, wind-dispelling, dehumidifying.Classify under category diaphoretic medicine pungent
Warm diaphoretic medicine.
Further, 5 parts of the described root of kudzu vine, 5 parts of radish seed, 6 parts of coix seed, 6 parts of the tuber of pinellia, 9 parts of stir-baked RADIX PAEONIAE ALBA, 4 parts of Poria cocos,
It is 9 parts of lotus seeds, 6 parts of Divine Comedy, 9 parts of nutmeg, windproof 5 parts.
Further, 6 parts of the described root of kudzu vine, 7 parts of radish seed, 7 parts of coix seed, 8 parts of the tuber of pinellia, 12 parts of stir-baked RADIX PAEONIAE ALBA, Poria cocos 6
It is part, 12 parts of lotus seeds, 8 parts of Divine Comedy, 10 parts of nutmeg, windproof 6 parts.
Further, 8 parts of the described root of kudzu vine, 8 parts of radish seed, 9 parts of coix seed, 9 parts of the tuber of pinellia, 15 parts of stir-baked RADIX PAEONIAE ALBA, Poria cocos 8
It is part, 15 parts of lotus seeds, 10 parts of Divine Comedy, 15 parts of nutmeg, windproof 8 parts.
Further, described radish seed is vinegar radish seed.
Further, the described root of kudzu vine, coix seed, the tuber of pinellia, lotus seeds, stir-baked RADIX PAEONIAE ALBA, Poria cocos, Divine Comedy, nutmeg, radish seed,
Windproof decoction is taken.
The present invention compared with prior art, has advantages below and beneficial effect：The present invention is based on to chronic diarrhea disease
The understanding and principle of reatment of shape mechanism, using directly oral method, tonification and purgation in combination, has tonifying Qi dampness elimination, the effect of function of spleen and stomach regulating
Fruit, evident in efficacy, quality is easily controlled, and stability is good, has no adverse reaction substantially.
Embodiment
The present invention is described in further detail with reference to embodiment, but the implementation of the present invention is not limited to this.
Embodiment 1：
A kind of Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom, including 5 ~ 8 parts of the root of kudzu vine in parts by weight, radish seed 5 ~ 8
Part, 6 ~ 9 parts of coix seed, 6 ~ 9 parts of the tuber of pinellia, 9 ~ 15 parts of stir-baked RADIX PAEONIAE ALBA, 4 ~ 8 parts of Poria cocos, 9 ~ 15 parts of lotus seeds, 6 ~ 10 parts of Divine Comedy, nutmeg 9
~ 15 parts, it is windproof 5 ~ 8 parts.
The root of kudzu vine can rise clear antidiarrheal based on clearing heat and promoting diuresis.
Coix seed plays a part of invigorating the spleen to arrest diarrhea strengthen immunity based on invigorating spleen to remove dampness, remove numbness antidiarrheal.
Lotus seeds are used for tonifying spleen and stopping diarrhea, reduce diarrhoea number.
Stir-baked RADIX PAEONIAE ALBA is used to press down liver and help the soft liver emergencies of spleen and relieve pain, and can treat and be suffered from abdominal pain caused by a variety of causes.
Poria cocos can invigorating the spleen for eliminating dampness, for reduce suffer from diarrhoea number.
Based on Divine Comedy strengthening the spleen and stomach.
Nutmeg is mainly used in reducing diarrhoea number based on middle benefit gas promoting the circulation of qi, relieving diarrhea with astringents.
Radish seed is primarily to facilitate ileum Rythmic contractions characteristic and suppresses gastric emptying.
Anti- wind energy dissipates liver depression, gas of being amusing plays a part of qi-regulating soothing liver and strengthening spleen.
The method of the present embodiment medicine preparation, including following steps：
Step S1：By above-mentioned whole Chinese medicine material medicines, to be soaked 30 minutes with clear water or pure water in advance, water consumption for immersion is 0.9 ~
1.1L；
Step S2：Chinese medicine material medicine after immersion and its liquid medicine of immersion are added in decocting container, capping decocts jointly,
Described decocting container is marmite, enamel ware or stainless steel, avoids and uses ironware；
Step S3：Decocting container herb liquid is seethed with excitement with high heat, reuse slow fire and boil 15 ~ 20 minutes, 2 need to be stirred when boiling medicine
~ 3 times；
Step S4：After the completion of decoction, add proper amount of clear water or pure water not to have medicine, carry out second and decoct, decoct duration and degree of heating method
Ibid, decocting time 15 ~ 20 minutes；
Step S5：Decoction is filtered out, it is endo-medicine to obtain decoction.
An auxiliary material of the invention can be decocted three times altogether, and for the first time plus 10 times of decoctings measured are boiled 2 hours, second plus 8
The decocting of amount is boiled 1 hour again, and the decoctings of third time plus 6 times of amounts are boiled 1 hour.The water of 10 times of described amounts is water consumption for immersion.With
This calculates water consumption when being easy to second, decocting for the third time.
Embodiment 2：
In the present embodiment, 5 parts described of the root of kudzu vine, 5 parts of radish seed, 6 parts of coix seed, 6 parts of the tuber of pinellia, 9 parts of stir-baked RADIX PAEONIAE ALBA, 4 parts of Poria cocos, lotus
It is 9 parts of son, 6 parts of Divine Comedy, 9 parts of nutmeg, windproof 5 parts.
Embodiment 3：
In the present embodiment, 6 parts described of the root of kudzu vine, 7 parts of radish seed, 7 parts of coix seed, 8 parts of the tuber of pinellia, 12 parts of stir-baked RADIX PAEONIAE ALBA, 6 parts of Poria cocos,
It is 12 parts of lotus seeds, 8 parts of Divine Comedy, 10 parts of nutmeg, windproof 6 parts.
Embodiment 4：
In the present embodiment, 8 parts described of the root of kudzu vine, 8 parts of radish seed, 9 parts of coix seed, 9 parts of the tuber of pinellia, 15 parts of stir-baked RADIX PAEONIAE ALBA, 8 parts of Poria cocos,
It is 15 parts of lotus seeds, 10 parts of Divine Comedy, 15 parts of nutmeg, windproof 8 parts.
Toxicology test：
Acute toxicity test：
Experimental observation, because LD50 can not be measured, therefore the measure of maximum dosage-feeding is carried out.Chinese medicine compound prescription prepared by embodiment 1
Mixture is dissolved in sterile saline, is configured to solution gavage mouse, is as a result shown, is given birth to medicine maximum administration concentration 9.65
Medicine/ml, for maximum administered volume 50ml/kg in being administered twice in 24 hours to mouse stomach, mouse maximum dosage-feeding is 763.25g
Crude drug/kg, animal do not occur adverse reaction and death, each internal organs no abnormality seen of anatomic observation.
Long term toxicity test：
SD rats 80 are applied in this experiment, and Chinese medicine compound prescription mixture prepared by embodiment 1 is dissolved in sterile saline, configuration
Into solution gavage, if control group and 24g, 35g, 49g crude drug/kg dosage groups, continuous gavage is administered 12 weeks, observes in the present invention
Influence of the drug composition to animal indices.Result of the test shows that successive administration 12 weeks, Chinese medicine composition of the invention is to big
The body weight of mouse, food ration, peripheral hemogram, clotting time, electrocardiogram, organ index etc. have no significant effect；Blood biochemical 12
Item index determining result, 12 weeks low dose group BiLi values of administration are higher than control group（P<0.05)；Low dose group, middle dose group TP values
Higher than control group（P<0.05), but within normal physiologic range, other indexs no significant difference compared with control group.Recover
Phase each administration group indices measured value and the more equal no significant difference of control group.Each internal organs gross examination of skeletal muscle no abnormality seen of each group.
The clinical statisticses data of various Chronic Diarrhea Patients is directed to using medicine of the present invention：
By the Clinical practice of 200 patients, wherein male patient 127, female patient 73, medication age object 20 ~ 60 years old.Wherein
It is minimum 21 years old, maximum 59 years old, average age 38 years old；Slight chronic diarrhea disease 42, moderate chronic diarrheal disease 72, severe chronic
Diarrheal disease 36.
Mr. Wang, male, 37 years old, native.Suffered from diarrhoea before half a year in the case of without obvious inducement, obvious after feed, abdomen
Number is rushed down to be for up to 6 times, with borborygmus in weak, abdomen, no stomachache, abdominal distension, no Nausea and vomiting, no heating, chilly, in half a year, body
Weight is obvious to mitigate 3kg.Chronic diarrhea symptom disappears after taking 3 courses for the treatment of orally using the prescription of the embodiment of the present invention 1, and energy has changed
It is kind.
It is described above, be only presently preferred embodiments of the present invention, any formal limitation not done to the present invention, it is every according to
Any simply modification, the equivalent variations made according to the technical spirit of the present invention to above example, each fall within the protection of the present invention
Within the scope of.
Claims (6)
- A kind of 1. Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom, it is characterised in that：Including the root of kudzu vine 5 ~ 8 in parts by weight Part, 5 ~ 8 parts of radish seed, 6 ~ 9 parts of coix seed, 6 ~ 9 parts of the tuber of pinellia, 9 ~ 15 parts of stir-baked RADIX PAEONIAE ALBA, 4 ~ 8 parts of Poria cocos, 9 ~ 15 parts of lotus seeds, Divine Comedy 6 ~ 10 parts, it is 9 ~ 15 parts of nutmeg, windproof 5 ~ 8 parts.
- A kind of 2. Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom according to claim 1, it is characterised in that：Including 5 parts of the root of kudzu vine in parts by weight, 5 parts of radish seed, 6 parts of coix seed, 6 parts of the tuber of pinellia, 9 parts of stir-baked RADIX PAEONIAE ALBA, 4 parts of Poria cocos, 9 parts of lotus seeds, god Bent 6 parts, it is 9 parts of nutmeg, windproof 5 parts.
- A kind of 3. Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom according to claim 1, it is characterised in that：Including 6 parts of the root of kudzu vine in parts by weight, 7 parts of radish seed, 7 parts of coix seed, 8 parts of the tuber of pinellia, 12 parts of stir-baked RADIX PAEONIAE ALBA, 6 parts of Poria cocos, 12 parts of lotus seeds, It is 8 parts of Divine Comedy, 10 parts of nutmeg, windproof 6 parts.
- A kind of 4. Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom according to claim 1, it is characterised in that：Including 8 parts of the root of kudzu vine in parts by weight, 8 parts of radish seed, 9 parts of coix seed, 9 parts of the tuber of pinellia, 15 parts of stir-baked RADIX PAEONIAE ALBA, 8 parts of Poria cocos, 15 parts of lotus seeds, It is 10 parts of Divine Comedy, 15 parts of nutmeg, windproof 8 parts.
- A kind of 5. Chinese medicine preparation for being advantageous to alleviate chronic diarrhea symptom according to claim 1, it is characterised in that：It is described Radish seed be vinegar radish seed.
- A kind of 6. Chinese medicine preparation that can treat gastric ulcer according to claim 1, it is characterised in that：The described root of kudzu vine, Coix seed, the tuber of pinellia, lotus seeds, stir-baked RADIX PAEONIAE ALBA, Poria cocos, Divine Comedy, nutmeg, radish seed, windproof decoction are taken.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232694A (en) * | 2015-10-29 | 2016-01-13 | 赵卫国 | Traditional Chinese medicine for treating diarrhea, preparing method of traditional Chinese medicine for treating diarrhea and medicine product of traditional Chinese medicine for treating diarrhea |
| CN106421084A (en) * | 2016-11-07 | 2017-02-22 | 成都泠汐尚品科技有限公司 | Traditional Chinese medicinal composition for treating chronic diarrhea |
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2017
- 2017-08-29 CN CN201710756371.6A patent/CN107582908A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232694A (en) * | 2015-10-29 | 2016-01-13 | 赵卫国 | Traditional Chinese medicine for treating diarrhea, preparing method of traditional Chinese medicine for treating diarrhea and medicine product of traditional Chinese medicine for treating diarrhea |
| CN106421084A (en) * | 2016-11-07 | 2017-02-22 | 成都泠汐尚品科技有限公司 | Traditional Chinese medicinal composition for treating chronic diarrhea |
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Application publication date: 20180116 |
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