CN107582843A - It is a kind of to be used for nourishing liver and kidney formula and its extraction process - Google Patents
It is a kind of to be used for nourishing liver and kidney formula and its extraction process Download PDFInfo
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- CN107582843A CN107582843A CN201710404593.1A CN201710404593A CN107582843A CN 107582843 A CN107582843 A CN 107582843A CN 201710404593 A CN201710404593 A CN 201710404593A CN 107582843 A CN107582843 A CN 107582843A
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Abstract
It is a kind of to be used for nourishing liver and kidney formula and its extraction process.The Radix Astragali, radix rehmanniae recen, the coptis, dogwood fruit, Chinese yam, the fleece-flower root, Eclipta prostrata, the fruit of glossy privet, the root of bidentate achyranthes, the radix paeoniae rubrathe, the red sage root, rhizoma atractylodis, Fructus Aurantii, the taste medicinal material of sealwort 14 adds water to cook 3 times, for the first time plus 10 times are measured water, second, three times plus 8 times are measured water, 1.5 hours every time, collecting decoction, filtration, filtrate is concentrated into (70 DEG C) Zuo You of relative density 1.38~1.40, add ethanol precipitation 3 times, first time alcohol content is 70%, second, alcohol content is 80% three times, stand 12 hours every time, filtration, filtrate recycling ethanol, obtain concentrate, dry, gained medicinal powder is main ingredient raw material.Prescription Chinese medicine is extracted the present invention and purifying process, after the effective substance mixing of acquisition, as the main ingredient raw material of nourishing liver and kidney side, is laid the foundation to prepare curative for effect, safely controllable, the small nourishing liver and kidney related formulation good to biddability of dose.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically, it is related to and a kind of is used for nourishing liver and kidney formula and its extraction process.
Background technology
For nourishing liver and kidney side as preparation in the institute of institute of traditional Chinese medicine of Tianzhang City, original side's decoction has applied to clinical more than 20 years.By
Long-term clinical application is observed, and the pretherapy and post-treatment check analysis of a large amount of cases, its is nourishing liver and kidney, supplementing qi and nourishing yin, the turbid effect of promoting blood circulationization
Substantially, thirsty more drinks caused by card are stayed to the cloudy all void of liver kidney qi of diabetes " illness that disappears phase ", turbid stasis, the paddy that disappears is easily hungry, urinates more, shape
Body is gradually thin, lassitude hypodynamia；Frequent micturition is muddy as cream, or Huang are red；It is dysphoria in chestpalms-soles, dry mouth and throat；Blurred vision, two dry and astringent；It is dizzy
The clinical efficacies such as tinnitus, soreness and weakness of waist and knees are obvious.
Morbidity of quenching one's thirst be unable to do without natural endowment constitution, negative and positive of qi and blood, and the overfeeding day after tomorrow is fertile, seven feelings sexual strain, is with middle burnt functions of spleen and stomach
Can imbalance, it is wet, turbid, become silted up the syndrome that is grown for its pathological product based on the defeated cloth of qi-blood-body fluid is not normal.Early stage：" spleen
Illness " is based on real example, liver-stomach disharmony, functional activity of QI being not smooth, body fluid can not normal defeated cloth, wet essential resistance of turbid；Mid-term：" quenching one's thirst ", with asthenic symptoms
Based on, taste deficiency of both qi and yin, the deficiency of vital energy fortune blood it is powerless, deficiency of Yin blood is involved and abstruse, gas the moon homogeny of clear fluid and blood, wear and tear and cause in turbid silt
Stop；Late period：" disappear illness ", complication of quenching one's thirst phase, simulataneous insufficiency and excessive, so that speen-kidney dificiency, the deficiency of liver-yin and kidney-yin, the turbid resistance network that becomes silted up.Misdiagnosis is controlled in mistake,
Protracted course of disease, and cause deficiency in both YIN and YANG.Then then thirsty more drinks, deficiency of kidney-QI, disturbance in qi transformation are hindered in rapid digestion of food and polyorexia, heat very Tianjin to the lung stomach fire of deficiency type
Then urine is more, and the fire of deficiency type secretly consumes qi-blood-body fluid, and then body is become thin, lassitude hypodynamia；The deficiency of the kidney yin, with the passing of time, yin deficiency affecting yang, gasification is lost for delay
Department, turbid yin bet, the unconsolidation of the kidney-qi is precise and tiny to leak, then frequent micturition is muddy such as cream or yellow red；Kidney opening at ear, waist are house of kidney, kidney deficiency
Then soreness of waist tinnitus；Mutually fiery high prosperous, then dysphoria in chestpalms-soles, dry mouth and throat；The liver and the kidney have a common source, liver opening at eye, deficiecny of liver-YIN, and mesh is become homeless
Support, then blurred vision, two dry and astringent.
Its pathogenesis can not be prevented further to send out completely clearly merely using Western medicine control blood glucose at present
Exhibition, effective treatment means are lacked to complication.In order to preferably release sufferer sufferings, the present invention is to treat diabetes " illness that disappears phase "
Liver kidney qi it is cloudy all empty, it is object that turbid stasis, which stays patient, develops and develops for the purpose of both safe and effective Chinese medicine preparation.
The content of the invention
Inventive formulation is with the Radix Astragali, radix rehmanniae recen, the coptis, dogwood fruit, Chinese yam, the fleece-flower root, Eclipta prostrata, the fruit of glossy privet, the root of bidentate achyranthes, red
Chinese herbaceous peony, the red sage root, rhizoma atractylodis, Fructus Aurantii, the taste medicinal material of sealwort 14 form nourishing liver and kidney side according to a certain percentage, and by using water extract-alcohol precipitation side
Prescription Chinese medicine is extracted method and purifying process, and after the effective substance mixing of acquisition, the main ingredient as nourishing liver and kidney side is former
Material, lays the foundation to prepare curative for effect, safely controllable, the small nourishing liver and kidney related formulation good to biddability of dose.
In order to solve the above-mentioned technical problem, the invention provides following technical scheme：It is a kind of to be used for nourishing liver and kidney match somebody with somebody
Side, including Radix Astragali 10-20g, radix rehmanniae recen 8-18g, coptis 5-7g, dogwood fruit 8-14g, Chinese yam 6-14g, fleece-flower root 8-18g, non-irrigated lotus
Careless 5-15g, fruit of glossy privet 5-15g, root of bidentate achyranthes 8-12g, radix paeoniae rubrathe 8-14g, red sage root 8-12g, rhizoma atractylodis 5-8g, Fructus Aurantii 5-8g, sealwort 8-
12g。
It is used for nourishing liver and kidney formula extraction process present invention also offers a kind of, its step is as follows：
It is the Radix Astragali, radix rehmanniae recen, the coptis, dogwood fruit, Chinese yam, the fleece-flower root, Eclipta prostrata, the fruit of glossy privet, the root of bidentate achyranthes, the radix paeoniae rubrathe, the red sage root, grey
Art, Fructus Aurantii, the taste medicinal material of sealwort 14 add water to cook 3 times, and for the first time plus 10 times of amount water, second and third time add 8 times of amount water, and 1.5 is small every time
When, collecting decoction, filter, filtrate is concentrated into (70 DEG C) Zuo You of relative density 1.38~1.40, adds ethanol precipitation 3 times, for the first time
Alcohol content is 70%, and second and third alcohol content is 80%, stands 12 hours every time, filtration, filtrate recycling ethanol, obtains concentrate,
Dry, gained medicinal powder is main ingredient raw material；
Content after extraction purification, addition dextrin is appropriate, and equivalent is progressively increased after method mixing, with 70% ethanol softwood, system
Grain, 60 DEG C of dryings, whole grain, produces nourishing liver and kidney granule.
Of the invention its nourishing liver and kidney, supplementing qi and nourishing yin, the turbid positive effect of promoting blood circulationization, to liver kidney qi the moon of diabetes " illness that disappears phase "
All void, turbid stasis stay thirsty more drinks caused by card, and the paddy that disappears is easily hungry, and urine is more, and body is gradually thin, lassitude hypodynamia；The muddy such as cream of frequent micturition, or
Huang Chi；It is dysphoria in chestpalms-soles, dry mouth and throat；Blurred vision, two dry and astringent；The clinical efficacies such as dizziness and tinnitus, soreness and weakness of waist and knees are obvious.
Embodiment
Embodiment 1
Weigh Radix Astragali 150g, radix rehmanniae recen 100g, coptis 60g, dogwood fruit 100g, Chinese yam 100g, fleece-flower root 100g, Eclipta prostrata
100g, fruit of glossy privet 100g, root of bidentate achyranthes 100g, radix paeoniae rubrathe 100g, red sage root 100g, rhizoma atractylodis 60g, Fructus Aurantii 60g, sealwort 100g, dextrin, ethanol
In right amount.
Extraction process is shown as to the Radix Astragali, radix rehmanniae recen, the coptis, dogwood fruit, Chinese yam, the fleece-flower root, Eclipta prostrata, the fruit of glossy privet, ox
Knee, the radix paeoniae rubrathe, the red sage root, rhizoma atractylodis, Fructus Aurantii, sealwort are extracted and purified, and particular content is mainly as follows：The Radix Astragali, radix rehmanniae recen, the coptis,
Dogwood fruit, Chinese yam, the fleece-flower root, Eclipta prostrata, the fruit of glossy privet, the root of bidentate achyranthes, the radix paeoniae rubrathe, the red sage root, rhizoma atractylodis, Fructus Aurantii, the taste medicinal material of sealwort 14 add decocting
Boil 3 times, first time plus 10 times of amount water, second and third time plus 8 times of amount water, 1.5 hours every time, collecting decoction, filter, filtrate concentration
To (70 DEG C) Zuo You of relative density 1.38~1.40, add ethanol precipitation 3 times, first time alcohol content is 70%, second and third containing alcohol
Measure as 80%, stand 12 hours every time, filtration, filtrate recycling ethanol, obtain concentrate, dry, gained medicinal powder is main ingredient raw material.
Extract the Radix Astragali, radix rehmanniae recen, the coptis, dogwood fruit, Chinese yam, the fleece-flower root, Eclipta prostrata, the fruit of glossy privet, the root of bidentate achyranthes, the radix paeoniae rubrathe, the red sage root,
Rhizoma atractylodis, Fructus Aurantii, sealwort, merge the content after extraction purification, addition dextrin is appropriate, and equivalent is progressively increased after method mixing, with 70% second
Alcohol softwood, granulation, 60 DEG C of dryings, whole grain, produces nourishing liver and kidney granule.
Claims (2)
1. a kind of be used for nourishing liver and kidney formula, it is characterised in that including Radix Astragali 10-20g, radix rehmanniae recen 8-18g, coptis 5-7g,
Dogwood fruit 8-14g, Chinese yam 6-14g, fleece-flower root 8-18g, Eclipta prostrata 5-15g, fruit of glossy privet 5-15g, root of bidentate achyranthes 8-12g, radix paeoniae rubrathe 8-
14g, red sage root 8-12g, rhizoma atractylodis 5-8g, Fructus Aurantii 5-8g, sealwort 8-12g.
2. a kind of be used for nourishing liver and kidney formula extraction process, it is characterised in that its step is as follows：
The Radix Astragali, radix rehmanniae recen, the coptis, dogwood fruit, Chinese yam, the fleece-flower root, Eclipta prostrata, the fruit of glossy privet, the root of bidentate achyranthes, the radix paeoniae rubrathe, the red sage root, rhizoma atractylodis, trifoliate orange
Shell, the taste medicinal material of sealwort 14 add water to cook 3 times, and for the first time plus 10 times of amount water, second and third time add 8 times of amount water, 1.5 hours every time, closed
And decocting liquid, filtration, filtrate are concentrated into (70 DEG C) Zuo You of relative density 1.38~1.40, add ethanol precipitation 3 times, first time alcohol content
For 70%, second and third alcohol content is 80%, stands 12 hours every time, filtration, filtrate recycling ethanol, obtains concentrate, is dried,
Gained medicinal powder is main ingredient raw material；
Content after extraction purification, addition dextrin is appropriate, and equivalent is progressively increased after method mixing, with 70% ethanol softwood, pelletizes, and 60
DEG C drying, whole grain, produces nourishing liver and kidney granule.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710404593.1A CN107582843A (en) | 2017-06-01 | 2017-06-01 | It is a kind of to be used for nourishing liver and kidney formula and its extraction process |
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| CN201710404593.1A CN107582843A (en) | 2017-06-01 | 2017-06-01 | It is a kind of to be used for nourishing liver and kidney formula and its extraction process |
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| CN107582843A true CN107582843A (en) | 2018-01-16 |
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| CN201710404593.1A Pending CN107582843A (en) | 2017-06-01 | 2017-06-01 | It is a kind of to be used for nourishing liver and kidney formula and its extraction process |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016074333A1 (en) * | 2014-11-15 | 2016-05-19 | 广西慧宝源制药有限公司 | Drug or health care product preventing or treating liver and kidney damage-related diseases and use thereof |
-
2017
- 2017-06-01 CN CN201710404593.1A patent/CN107582843A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016074333A1 (en) * | 2014-11-15 | 2016-05-19 | 广西慧宝源制药有限公司 | Drug or health care product preventing or treating liver and kidney damage-related diseases and use thereof |
Non-Patent Citations (3)
| Title |
|---|
| 崔存利等: "从脾肾两虚论治老年性糖尿病32例", 《山东中医杂志》 * |
| 方亮: "《药剂学》", 31 March 2016, 中国医药科技出版社 * |
| 邓修: "《中药制药工程与技术》", 31 May 2008, 华东理工大学出版社 * |
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Application publication date: 20180116 |