CN104001078A - Traditional Chinese medicine preparation for treating diabetic nephropathy and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating diabetic nephropathy and preparation method thereof Download PDFInfo
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- CN104001078A CN104001078A CN201410247485.4A CN201410247485A CN104001078A CN 104001078 A CN104001078 A CN 104001078A CN 201410247485 A CN201410247485 A CN 201410247485A CN 104001078 A CN104001078 A CN 104001078A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating diabetic nephropathy, and a preparation method thereof. The traditional Chinese medicine preparation comprises the following traditional Chinese medicine raw materials in parts by weight: 6g of angelica sinensis, 6g of carthamus tinctorius, 8g of astragalus membranaceus, 6g of prepared rheum officinale, 12g of medlar, 9g of coix seed, 10g of eucommia ulmoides, 8g of codonopsis pilosula, 15g of poria cocos, 10g of fried atractylodes macrocephala, 15g of Chinese yam and 9g of dried tangerine or orange peel. The traditional Chinese medicine preparation for treating diabetic nephropathy, which is disclosed by the invention, adopts completely natural traditional Chinese medicine materials, is reasonable in pharmacy, definite in curative effect, low in cost and very high in clinical practical value.
Description
Technical field
The present invention relates to a kind of Chinese drugs agentia and preparation method for the treatment of diabetic nephropathy.
Background technology
Diabetic nephropathy (DN) is clinical common and multiple diabetic complication.Be one of complication that diabetes are the most serious, diabetic nephropathy is the main microvascular complications of diabetes, mainly refers to diabetic glomerulosclerosis, a kind of taking vascular lesion as main Glomerular lesions.In early days how asymptomatic, blood pressure can be normal or higher.Its incidence rate is along with the course of disease of diabetes extends and increases.The early stage kidney volume of diabetes increases, glomerular filtration rate increases, be high filtration state, engender space protein urine or microalbuminuria later, along with albuminuria, edema, hypertension, glomerular filtration rate reduction appear continuing in the prolongation of the course of disease, and then renal insufficiency, uremia, be one of main cause of death of diabetes.
At present, have a variety ofly for the means for the treatment of clinically this class disease, although western medicine has certain effect, it is short that Western medicine has drug effect, and the shortcoming of curing the symptoms, not the disease adds that the pharmacy cost of Western medicine is high, has increased the weight of to a certain extent people's financial burden.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of Chinese drugs agentia for the treatment of diabetic nephropathy, and this Chinese drugs agentia adopts the Chinese medicinal material of All Pure Nature, and medication is reasonable, and determined curative effect is with low cost, has very high value for clinical application.。
For addressing the above problem, the present invention is achieved through the following technical solutions:
Treat a Chinese drugs agentia for diabetic nephropathy, this raw material of Chinese medicine comprises following parts by weight proportioning: 6 grams of Radix Angelicae Sinensis, 5 grams of Rhizoma Chuanxiongs, 6 grams, Flos Carthami, 8 grams of the Radixs Astragali, 6 grams of Radix et Rhizoma Rhei (processed), 12 grams of Fructus Lyciis, Semen Coicis 9,10 grams of the Cortexs Eucommiae, 8 grams of Radix Codonopsis, 15 grams, Poria, 10 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 15 grams of Rhizoma Dioscoreaes, 9 grams of Pericarpium Citri Reticulataes;
Another technical problem that the present invention will solve is to provide a kind of preparation method of Chinese drugs agentia for the treatment of diabetic nephropathy.
For solving the problems of the technologies described above, the present invention adopts following technical scheme: comprise the following steps:
1) extract by weight ratio 6 grams of Radix Angelicae Sinensis, 5 grams of Rhizoma Chuanxiongs, 6 grams, Flos Carthami, 8 grams of the Radixs Astragali, 6 grams of Radix et Rhizoma Rhei (processed), 12 grams of Fructus Lyciis, Semen Coicis 9,10 grams of the Cortexs Eucommiae, 8 grams of Radix Codonopsis, 15 grams, Poria, 10 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 15 grams of Rhizoma Dioscoreaes, 9 grams of Pericarpium Citri Reticulataes, clean and dry, for subsequent use;
2) get step 1) Chinese crude drug is positioned in marmite, adds water to submerge, and infusion 60 minutes, stirs medical material while decocting, and stirring number of times is 2-3 time, has decocted rear elimination medicinal residues, taking liquid.
3) get step 2) in the infusion 30 minutes again of the medicinal residues that stay, decocted rear elimination medicinal residues, taking liquid, mixes the medicinal liquid of enduring out for 2 times, is Chinese drugs agentia of the present invention.
The Chinese drugs agentia of diabetic nephropathy of the present invention, its medical material efficacy effect is respectively:
1, Radix Angelicae Sinensis: enrich blood, invigorate blood circulation, moisturize laxation; 2, Rhizoma Chuanxiong: pungent loose temperature is logical, blood circulation promoting and blood stasis dispelling; 3, Flos Carthami: blood circulation promoting and blood stasis dispelling, wet dissipation goes to swell; 4, the Radix Astragali: benefiting QI for strengthening the superficies, arresting sweating is admittedly de-, holder skin ulcer granulation promoting, inducing diuresis to remove edema; 5, Radix et Rhizoma Rhei (processed): clearing away heat and loosing the bowels, blood circulation promoting and blood stasis dispelling; 6, Fructus Lycii: nourishing YIN and supplementing blood, replenishing vital essence to improve eyesight; 7, Semen Coicis: invigorating spleen for diuresis, dampness removing eliminating impediment, clearing away heat and discharging pus, eliminating damp-heat; 8, the Cortex Eucommiae: invigorating the liver and kidney, strong waist knee joint, bone and muscle strengthening; 9, Radix Codonopsis: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; 10, Poria: promoting diuresis to eliminate damp pathogen, invigorating the spleen for dissipating phlegm, mind tranquilizing and the heart calming, relieves internal heat anticancer; 11, Rhizoma Atractylodis Macrocephalae (parched): invigorating the spleen and benefiting QI, dampness diuretic, dehumidifying benefit is dry, and middle QI invigorating, and warming middle-JIAO goes in taste wet; 12, Rhizoma Dioscoreae: strengthening the spleen and stomach, lung benefiting kidney, tonify deficiency is won; 13, Pericarpium Citri Reticulatae: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.
The beneficial effect that the present invention treats the Chinese drugs agentia of diabetic nephropathy is: this Chinese drugs agentia adopts the Chinese medicinal material of All Pure Nature, and medication is reasonable, determined curative effect, and medical cost is low, and safety has no side effect.
Detailed description of the invention
For further understanding feature of the present invention, technological means and the specific purposes that reach, function, with detailed description of the invention, the present invention is described in further detail below.
A kind of Chinese drugs agentia for the treatment of diabetic nephropathy of the present invention, it is to extract 6 grams of Radix Angelicae Sinensis, 5 grams of Rhizoma Chuanxiongs, 6 grams, Flos Carthami, 8 grams of the Radixs Astragali, 6 grams of Radix et Rhizoma Rhei (processed), 12 grams of Fructus Lyciis, Semen Coicis 9,10 grams of the Cortexs Eucommiae, 8 grams of Radix Codonopsis, 15 grams, Poria, 10 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 15 grams of Rhizoma Dioscoreaes, 9 grams of Pericarpium Citri Reticulataes by following weight portion proportioning;
The Chinese drugs agentia of described treatment diabetic nephropathy and the manufacturing process of preparation method are as follows:
1) extract by weight ratio 6 grams of Radix Angelicae Sinensis, 5 grams of Rhizoma Chuanxiongs, 6 grams, Flos Carthami, 8 grams of the Radixs Astragali, 6 grams of Radix et Rhizoma Rhei (processed), 12 grams of Fructus Lyciis, Semen Coicis 9,10 grams of the Cortexs Eucommiae, 8 grams of Radix Codonopsis, 15 grams, Poria, 10 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 15 grams of Rhizoma Dioscoreaes, 9 grams of Pericarpium Citri Reticulataes, clean and dry, for subsequent use;
2) get step 1) Chinese crude drug is positioned in marmite, adds water to submerge, and infusion 60 minutes, stirs medical material while decocting, and stirring number of times is 2-3 time, has decocted rear elimination medicinal residues, taking liquid.
3) get step 2) in the infusion 30 minutes again of the medicinal residues that stay, decocted rear elimination medicinal residues, taking liquid, mixes the medicinal liquid of enduring out for 2 times, is Chinese drugs agentia of the present invention.
Experimental example:
1, experimental subject: 40 state of an illness are diabetic nephropathy III phase patient, are divided into two groups by drug administration difference, every group of 20 people.
2, experimental technique: 20 people of matched group take Western medicine, one day 3 times; 20 people of experimental group use Chinese drugs agentia of the present invention, and every day, sooner or later respectively be once 3 months writing time, and recording number of times is 1.
Points for attention: avoid on an empty stomach and eat, give full play to affect drug effect.
3, experimental result:
From experimental result, the cure rate of matched group is only 85%, and the cure rate of Chinese drugs agentia of the present invention is up to 95%, and matched group has two people to occur side effect simultaneously, and the phenomenon of side effect does not appear in experimental group.
From experimental result, the present invention has to treatment diabetic nephropathy effect that curative effect is high, have no side effect.
Can draw thus, the Chinese drugs agentia that the present invention is a kind of treats diabetic nephropathy is in than conventional therapy medicine, and the present invention adopts the Chinese medicinal material of All Pure Nature, medication is reasonable, and safety has no side effect, determined curative effect, medicine cost is low, and has very high value for clinical application typical case
King so-and-so, man, 45 years old, diabetic nephropathy III phase patient, had edema, myasthenia of limbs, inappetence, feels sick, the symptom such as vomiting.Before using a month aftersensation spirit of medication of the present invention not take this Chinese medicine, there is obvious improvement, take and found that after two months edema phenomenon is clearly better, the phenomenon of feeling sick, vomit obviously reduces, and takes after three months, and indices is all in range of normal value on inspection.
The present invention is not limited to above-mentioned preferred forms, and other any or akin products identical with the present invention that anyone draws under enlightenment of the present invention, within all dropping on protection scope of the present invention.
Claims (2)
1. a Chinese drugs agentia for the treatment of diabetic nephropathy, is characterized in that: this raw material of Chinese medicine comprises following parts by weight proportioning: 6 grams of Radix Angelicae Sinensis, 5 grams of Rhizoma Chuanxiongs, 6 grams, Flos Carthami, 8 grams of the Radixs Astragali, 6 grams of Radix et Rhizoma Rhei (processed), 12 grams of Fructus Lyciis, Semen Coicis 9,10 grams of the Cortexs Eucommiae, 8 grams of Radix Codonopsis, 15 grams, Poria, 10 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 15 grams of Rhizoma Dioscoreaes, 9 grams of Pericarpium Citri Reticulataes.
2. a preparation method for the Chinese drugs agentia for the treatment of diabetic nephropathy as claimed in claim 1, is characterized in that, comprises the following steps:
1) extract by weight ratio 6 grams of Radix Angelicae Sinensis, 5 grams of Rhizoma Chuanxiongs, 6 grams, Flos Carthami, 8 grams of the Radixs Astragali, 6 grams of Radix et Rhizoma Rhei (processed), 12 grams of Fructus Lyciis, Semen Coicis 9,10 grams of the Cortexs Eucommiae, 8 grams of Radix Codonopsis, 15 grams, Poria, 10 grams of Rhizoma Atractylodis Macrocephalae (parched)s, 15 grams of Rhizoma Dioscoreaes, 9 grams of Pericarpium Citri Reticulataes, clean and dry, for subsequent use;
2) get step 1) Chinese crude drug is positioned in marmite, adds water to submerge, and infusion 60 minutes, stirs medical material while decocting, and stirring number of times is 2-3 time, has decocted rear elimination medicinal residues, taking liquid.
3) get step 2) in the infusion 30 minutes again of the medicinal residues that stay, decocted rear elimination medicinal residues, taking liquid, mixes the medicinal liquid of enduring out for 2 times, is Chinese drugs agentia of the present invention.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104398917A (en) * | 2014-11-12 | 2015-03-11 | 高永学 | Traditional Chinese medicinal composition capable of stabilizing type 2 diabetes mellitus condition and preventing and treating diabetic nephropathy |
| CN106038926A (en) * | 2016-08-16 | 2016-10-26 | 汪培杰 | Traditional Chinese medicine for treating diabetes and preparation method thereof |
| CN107737279A (en) * | 2017-11-21 | 2018-02-27 | 武汉大学 | A kind of Chinese medicine preparation for treating diabetic nephropathy and preparation method thereof |
| CN109224000A (en) * | 2018-11-23 | 2019-01-18 | 河南中医药大学 | A kind of Chinese medicine enema delaying diabetic nephropathy |
| CN112245534A (en) * | 2019-07-02 | 2021-01-22 | 河南中立生物科技有限公司 | Traditional Chinese medicine diabetic nephropathy patch and preparation method thereof |
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| WO1992006954A2 (en) * | 1990-10-15 | 1992-04-30 | Pfizer Inc. | Pyrrolidine dione derivatives |
| CN102302563A (en) * | 2011-09-13 | 2012-01-04 | 梁海勇 | Chinese medicinal composition for treating chronic kidney failure and preparation method thereof |
| CN102579894A (en) * | 2012-02-10 | 2012-07-18 | 广东省中医院 | Chinese materia medica preparation for curing chronic kidney disease and preparation method of Chinese materia medica preparation |
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2014
- 2014-06-05 CN CN201410247485.4A patent/CN104001078A/en active Pending
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| WO1992006954A2 (en) * | 1990-10-15 | 1992-04-30 | Pfizer Inc. | Pyrrolidine dione derivatives |
| CN102302563A (en) * | 2011-09-13 | 2012-01-04 | 梁海勇 | Chinese medicinal composition for treating chronic kidney failure and preparation method thereof |
| CN102579894A (en) * | 2012-02-10 | 2012-07-18 | 广东省中医院 | Chinese materia medica preparation for curing chronic kidney disease and preparation method of Chinese materia medica preparation |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104398917A (en) * | 2014-11-12 | 2015-03-11 | 高永学 | Traditional Chinese medicinal composition capable of stabilizing type 2 diabetes mellitus condition and preventing and treating diabetic nephropathy |
| CN104398917B (en) * | 2014-11-12 | 2018-02-23 | 高永学 | The Chinese medicine composition of the stable type II diabetes state of an illness of energy and prophylactic treatment diabetic nephropathy |
| CN106038926A (en) * | 2016-08-16 | 2016-10-26 | 汪培杰 | Traditional Chinese medicine for treating diabetes and preparation method thereof |
| CN107737279A (en) * | 2017-11-21 | 2018-02-27 | 武汉大学 | A kind of Chinese medicine preparation for treating diabetic nephropathy and preparation method thereof |
| CN109224000A (en) * | 2018-11-23 | 2019-01-18 | 河南中医药大学 | A kind of Chinese medicine enema delaying diabetic nephropathy |
| CN109224000B (en) * | 2018-11-23 | 2021-04-13 | 河南中医药大学 | Enema traditional Chinese medicine liquid for delaying diabetic nephropathy |
| CN112245534A (en) * | 2019-07-02 | 2021-01-22 | 河南中立生物科技有限公司 | Traditional Chinese medicine diabetic nephropathy patch and preparation method thereof |
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Application publication date: 20140827 |