CN107551124A - The preparation and method of hemophilia and angiohemophilia caused by treating abnormal heat bleeding - Google Patents
The preparation and method of hemophilia and angiohemophilia caused by treating abnormal heat bleeding Download PDFInfo
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- CN107551124A CN107551124A CN201710938913.1A CN201710938913A CN107551124A CN 107551124 A CN107551124 A CN 107551124A CN 201710938913 A CN201710938913 A CN 201710938913A CN 107551124 A CN107551124 A CN 107551124A
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Abstract
It is a kind of treat abnormal heat bleeding caused by the preparation and method of hemophilia and angiohemophilia.Preparation by dosage by weight than agents raw material be made：Radix rehmanniae recen 12 32, the wind-weed 9 24, radix scrophulariae 9 24, golden cypress 6 15, radix scutellariae 6 15, the fruit of glossy privet 6 15, eclipta 6 15, bark of ash 6 15, the root bark of Chinese wolf-berry 6 15, madder 9 24, cacumen biotae 6 15, moutan bark 6 15, Asian puccoon 6 15, licorice 4 10.Invention formulation is to extract the active ingredient in material medicine using the method for boiling extraction, and keeps its activity, so not only can greatly improve the dissolution rate of active ingredient in medicine, and contributes to the absorption of medicine, so as to improve its bioavilability.In addition, the medicine of the present invention is pure Chinese medicine compound preparation, thus toxic side effect will not be produced after patient's long-term use, so security is good.In addition, the preparation method technique of the present invention is simple, it is easy to operate.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof, is used more particularly to one kind using Chinese medicine as made of raw material
In treating hemophilia and the compound Chinese medicinal preparation of angiohemophilia and preparation method thereof caused by abnormal heat bleeding.
Background technology
Hemophilia is a kind of hereditary hemorrhagic disease.Its common trait is active enzyme thrombin dyspoiesis, the clotting time
Long, patient has mild trauma can severe haemorrhage together.Angiohemophilia is one kind with prolonged bleeding time, the anti-blood of blood plasma
The sick globulinopenia of friend, and Adherence of Platelet reduce the hemorrhagic disease being characterized.Although clinically it is used to treat blood at present
The types of drugs of friendly disease and angiohemophilia is many but more due to causing the factor of hemophilia and angiohemophilia to have
Kind, and hemophilia and angiohemophilia also divide polytype, therefore these medicine lack of targeted, and the course for the treatment of is relatively
It is long, and some drugs have certain side effect or allergic reaction, so the blood belonged to after taking for treatment caused by abnormal heat bleeding
Effect is undesirable for friendly disease and this disease of angiohemophilia.
The content of the invention
In order to solve the above problems, it is an object of the invention to provide one kind be used for treat abnormal heat bleeding caused by hemophilia and
Compound Chinese medicinal preparation of angiohemophilia and preparation method thereof.
In order to achieve the above object, hemophilia and angiohemophilia caused by treatment abnormal heat bleeding provided by the invention
Preparation by dosage by weight than agents raw material be made：
The preparation method of the preparation of hemophilia and angiohemophilia caused by described treatment abnormal heat bleeding is will be above-mentioned
Medicine material is weighed and mixed according to proportioning, is then soaked 25 minutes, is decocted 30 minutes afterwards, filter and remove residue
Hemophilia and the compound Chinese medicinal preparation of angiohemophilia caused by described treatment abnormal heat bleeding is made.
Described compound Chinese medicinal preparation can be made with conventional pharmaceutic adjuvant granule, tablet, capsule, syrup,
Oral liquid, pill and paste.
Provided by the present invention for hemophilia and the compound Chinese medicinal preparation of angiohemophilia caused by treatment abnormal heat bleeding
It is that the active ingredient in material medicine is extracted using the method for boiling extraction, and keeps its activity, so can not only makes medicine
The dissolution rate of middle active ingredient greatly improves, and contributes to the absorption of medicine, so as to improve its bioavilability.Separately
Outside, medicine of the invention is pure Chinese medicine compound preparation, thus toxic side effect will not be produced after patient's long-term use, so security
It is good.In addition, the preparation method technique of the present invention is simple, it is easy to operate.
Embodiment
Hemophilia and angiohemophilia complicated symptoms, course of disease delay, complication are more.Clinical common asthenic symptoms, real example
With syndrome of intermingled deficiency and excess etc..This side makes laws in nourishing Yin and clearing heat.Radix rehmanniae recen sweetness and bitterness is trembled with fear in side, clearing heat and cooling blood, nourishing Yin and promoting production of body fluid, is that heat-clearing is cool
The key medicine of blood hemostasis, therefore be monarch drug in a prescription.Wind-weed bitter sweet is trembled with fear, clearing heat-fire, fluid dryness；Golden cypress bitter cold, heat-clearing and damp-drying drug, purging intense heat remove
Steam, detoxification sore treatment；Fruit of glossy privet sweetness and bitterness is cool, nourishing liver and kidney, and crow must improving eyesight；Bark of ash is arduous flat, wind-damp dispelling, removes obstruction in channels to relieve pain, reducing the asthenic fever,
Clearing away damp-heat；Madder bitter cold, cooling blood and removing stasis hemostasis, stimulates the menstrual flow；Moutan bark bitter sweet is slightly cold, clearing heat and cooling blood, promoting blood circulation, all medicines of the above,
It is clearing heat and detoxicating, cooling blood and removing stasis, nourishing Yin and moistening dryness, it is altogether ministerial drug.Radix scrophulariae sweetness and bitterness is salty to be slightly cold, clearing heat and cooling blood, purging intense heat and detonicating, enriching yin；It is yellow
A kind of reed mentioned in ancient books bitter cold, heat-clearing and damp-drying drug, purging intense heat and detonicating, it is longer than clear middle dampness-heat in upper jiao especially；Eclipta sweet acid is trembled with fear, nourishing liver and kidney, cooling blood and hemostasis；Ground
Bone skin is sweet cold, and cool blood is except steaming, clearing lung-heat fall fire；Cacumen biotae is bitter cold, cooling blood and hemostasis, preventing phlegm from forming and stopping coughing；Asian puccoon is sweet salty-cold, and heat-clearing is cool
Blood, promoting blood circulation, promoting eruption of detoxifying, all medicines of the above, clearing heat and cooling blood, enriching yin removing toxic substances is nourishing liver and kidney, is altogether adjutant.Licorice is sweet flat, tonifying spleen
QI invigorating, clearing heat and detoxicating analgesic, coordinating the drug actions of a prescription, thinking makes medicine.Our nourishing Yin and clearing heat, cooling blood and hemostasis, therefore go out suitable for treatment abnormal heat
Hemophilia and angiohemophilia caused by blood.
With reference to embodiment to provided by the present invention for hemophilia caused by treatment abnormal heat bleeding and vascular vacation blood friend
Compound Chinese medicinal preparation of disease and preparation method thereof is described in detail.
Embodiment 1：
What the present embodiment provided is used for hemophilia and the Chinese medicine compound prescription system of angiohemophilia caused by treating abnormal heat bleeding
Agent by dosage by weight than agents raw material be made：
The described preparation for being used for hemophilia and the compound Chinese medicinal preparation of angiohemophilia caused by treating abnormal heat bleeding
Method is that said medicine raw material is weighed and mixed according to proportioning, then soaks 25 minutes, decocts 30 minutes afterwards,
Filter and remove residue can be made into hemophilia and the compound Chinese medicinal preparation of angiohemophilia caused by described treatment abnormal heat bleeding.
In addition, granule, tablet, capsule, sugar can be made with conventional pharmaceutic adjuvant in described compound Chinese medicinal preparation
Starch agent, oral liquid, pill and paste.
Embodiment 2：
What the present embodiment provided is used for hemophilia and the Chinese medicine compound prescription system of angiohemophilia caused by treating abnormal heat bleeding
Agent by dosage by weight than agents raw material be made：
Preparation method is the same as embodiment 1.
Embodiment 3：
What the present embodiment provided is used for hemophilia and the Chinese medicine compound prescription system of angiohemophilia caused by treating abnormal heat bleeding
Agent by dosage by weight than agents raw material be made：
Preparation method is the same as embodiment 1.
Provided by the present invention for hemophilia and the compound Chinese medicinal preparation of angiohemophilia caused by treatment abnormal heat bleeding
In brown to sepia；Gas is light, mildly bitter flavor.In order to verify the therapeutic effect of the compound Chinese medicinal preparation, the present inventor utilizes above-mentioned
Compound Chinese medicinal preparation has carried out the clinical sight of system to 301 patients with abnormal heat bleeding type hemophilia and angiohemophilia
Examine, wherein 21-30 year patient 80,31-40 year 115,41-50 year 106, each medication 150ml, 3 times a day, 120 days
For 1 course for the treatment of.(bleeding disappears substantially) 161 is cured altogether after 1 course of therapy, accounts for 53.5%；Effectively (cardinal symptom
Have improvement) 113, account for 37.5%；Invalid (cardinal symptom is without improvement) 27, accounts for 9.0%；Total effective rate is 91.0%.Through 2
223 are cured after course of therapy altogether, accounts for 74.1%；Effective 65, account for 21.6%；Invalid 13, account for 4.3%；Total effective rate is
95.7%.
Meanwhile the present inventor is analyzed the relation between therapeutic effect and age, therapeutic effect and the course for the treatment of, analysis
As a result 1, table 2 is shown in Table respectively.
Table 1：Compound Chinese medicinal preparation therapeutic effect provided by the invention and age correlations table
By the data x in above-mentioned table 12Method of inspection is calculated, and is as a result 0.050 ＞ P ＞ 0.025, it is possible thereby to demonstrate,prove
It is bright to take compound Chinese medicinal preparation provided by the invention to treat abnormal heat bleeding type hemophilia and angiohemophilia, to each age
The therapeutic effect of group does not change with the age.
Table 2：Compound Chinese medicinal preparation therapeutic effect provided by the invention and course for the treatment of relation table
By the data x in above-mentioned table 22Method of inspection is calculated, and is as a result P ＜ 0.005, it is possible thereby to prove to take this
The compound Chinese medicinal preparation provided is provided and treats abnormal heat bleeding type hemophilia and angiohemophilia, with the going deep into for the treatment of,
Cure rate, effective percentage significantly improve.
Claims (3)
1. it is a kind of treat abnormal heat bleeding caused by the preparation of hemophilia and angiohemophilia, it is characterised in that：Described treatment
The preparation of hemophilia caused by abnormal heat bleeding and angiohemophilia by dosage by weight than agents raw material be made：
A kind of 2. preparation of the preparation of hemophilia and angiohemophilia caused by treatment abnormal heat bleeding as claimed in claim 1
Method, it is characterised in that：Described preparation method is that said medicine raw material is weighed and mixed according to proportioning, then adds water
Immersion 25 minutes, decoct 30 minutes afterwards, filter and remove residue can be made into hemophilia and blood vessel caused by described treatment abnormal heat bleeding
The compound Chinese medicinal preparation of property hemogenia.
3. preparation method according to claim 2, it is characterised in that：Described compound Chinese medicinal preparation can be with conventional medicine
Granule, tablet, capsule, syrup, oral liquid, pill and paste is made with auxiliary material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710938913.1A CN107551124A (en) | 2017-09-30 | 2017-09-30 | The preparation and method of hemophilia and angiohemophilia caused by treating abnormal heat bleeding |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710938913.1A CN107551124A (en) | 2017-09-30 | 2017-09-30 | The preparation and method of hemophilia and angiohemophilia caused by treating abnormal heat bleeding |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107551124A true CN107551124A (en) | 2018-01-09 |
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ID=60985149
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710938913.1A Withdrawn CN107551124A (en) | 2017-09-30 | 2017-09-30 | The preparation and method of hemophilia and angiohemophilia caused by treating abnormal heat bleeding |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107551124A (en) |
-
2017
- 2017-09-30 CN CN201710938913.1A patent/CN107551124A/en not_active Withdrawn
Non-Patent Citations (1)
| Title |
|---|
| 王启政: "《实用中医血液病治疗学》", 31 March 1994, 中国中医药出版社 * |
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| PB01 | Publication | ||
| PB01 | Publication | ||
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| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180109 |