CN107550974A - Externally-applied medicinal composition of facial paralysis and application thereof - Google Patents
Externally-applied medicinal composition of facial paralysis and application thereof Download PDFInfo
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- CN107550974A CN107550974A CN201711052088.1A CN201711052088A CN107550974A CN 107550974 A CN107550974 A CN 107550974A CN 201711052088 A CN201711052088 A CN 201711052088A CN 107550974 A CN107550974 A CN 107550974A
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Abstract
The present invention relates to externally-applied medicinal composition of facial paralysis and application thereof, belong to pharmaceutical technology field.Present invention solves the technical problem that it is to provide the externally-applied medicinal composition of facial paralysis.The active component of the externally-applied medicinal composition is prepared by the Chinese medicine of following parts by weight：5~7 parts of Radix Angelicae Sinensis, 5~7 parts of the Radix Astragali, 1~3 part of scorpio, 1~3 part of centipede, 2~4 parts of stiff silkworm, 2~4 parts of earthworm, 1~3 part of long-noded pit viper, 2~4 parts of cicada slough.The externally-applied medicinal composition of the present invention, there is the effect of promoting blood circulation and removing obstruction in channels, QI invigorating Wen Yang, expelling wind and clearing away cold, have good therapeutic effect to facial paralysis insufficiency of vital energy and blood folder chill disease.It is administered by the way of external application, toxic side effect can be reduced on the premise of therapeutic effect is ensured, and be not easy allergy, securely and reliably, it is wide is applicable crowd's scope.
Description
Technical field
The present invention relates to externally-applied medicinal composition of facial paralysis and application thereof, belong to pharmaceutical technology field.
Background technology
Facial paralysis, i.e. facial neuritis, facioplegia (i.e. facial paralysis), " wapperijaw bar ", " facial paralysis " are commonly called as, is with face
Portion's mimetic musculature dyskinesia is a kind of disease of principal character.It is a kind of common disease, frequently-occurring disease, is not limited by the age
System.General symptom is facial paralysis, and often the action such as most basic lift eyebrow, eye closing, drum mouth can not all be completed patient.
The traditional Chinese medical science thinks, facial paralysis is to be caused face or left or right not by being attacked outside the perverse trend such as chill is wet by facial yang channel mostly
Then, in the treatment, general outer Zhiduo County is used based on acupuncture, and physical treatment is usually controlled using therapy, medicines such as ultrashort wave ultrasonic waves
It is mostly oral medicinal herb to treat.But the disease, due to the characteristics of developing, often treatment early efficacy is less obvious, or even aggravates, and makes trouble
Person's facial perception Ipsilateral is uncomfortable.The method of useful finless eel blood external application for curing facial paralysis among the people, but because finless eel blood contains a large amount of diseases
Poison, it is abnormally dangerous.
Patent CN101991638A discloses a kind of pharmaceutical composition of facial paralysis and its production and use, for this
The inventor of invention early stage research, use Radix Angelicae Sinensis, the Radix Astragali, scorpio, earthworm, centipede, stiff silkworm, cicada slough etc. for bulk drug preparation and
Into the pharmaceutical composition is medicine for oral administration, and oral medicinal herb, due to by administration species, time, dosage and decomposition excretion in vivo
Influence, make blood concentration unstable, diseased region drug concentration may it is low, so as to affect the treatment.In addition, medicine for oral administration,
Its toxic side effect can also produce certain influence to patient.
The content of the invention
For drawbacks described above, present invention solves the technical problem that being to provide the externally-applied medicinal composition of facial paralysis.
The externally-applied medicinal composition of facial paralysis of the present invention, its active component by following parts by weight Chinese medicine or Chinese medicine
Extract solution is prepared：5~7 parts of Radix Angelicae Sinensis, 5~7 parts of the Radix Astragali, 1~3 part of scorpio, 1~3 part of centipede, 2~4 parts of stiff silkworm, earthworm 2~
4 parts, 1~3 part of long-noded pit viper, 2~4 parts of cicada slough.
Preferably, its active component is prepared by the Chinese medicine or Chinese medicine extract solution of following parts by weight：7 parts of Radix Angelicae Sinensis,
5 parts of the Radix Astragali, 2 parts of scorpio, 1 part of centipede, 3 parts of stiff silkworm, 4 parts of earthworm, 1 part of long-noded pit viper, 3 parts of cicada slough.
It is further preferred that the Radix Astragali is astragalus root.
The pharmaceutical composition of the present invention is external used medicine, has the effect of promoting blood circulation and removing obstruction in channels, QI invigorating Wen Yang, expelling wind and clearing away cold, is led to
Cross and apply the medicine, the symptom for carrying out facial paralysis can be improved.
Studied by Long-term clinical, the present invention also provides facial paralysis effect more significant externally-applied medicinal composition, upper
State and with the addition of rhodiola root, balloonflower root, rhizome of chuanxiong, ginseng and cultivated land on the basis of pharmaceutical composition.
The active component of the pharmaceutical composition is prepared by the Chinese medicine or Chinese medicine extract solution of following parts by weight：Radix Angelicae Sinensis
5~7 parts, 5~7 parts of the Radix Astragali, 1~3 part of scorpio, 1~3 part of centipede, 2~4 parts of stiff silkworm, 2~4 parts of earthworm, 1~3 part of long-noded pit viper, cicada
Slough off 2~4 parts, 5~7 parts of rhodiola root, 1~2 part of balloonflower root, 2~4 parts of rhizome of chuanxiong, 1~3 part of ginseng, 1~3 part of cultivated land.
Preferably, its active component is prepared by the Chinese medicine or Chinese medicine extract solution of following parts by weight：7 parts of Radix Angelicae Sinensis,
5 parts of the Radix Astragali, 2 parts of scorpio, 1 part of centipede, 3 parts of stiff silkworm, 4 parts of earthworm, 1 part of long-noded pit viper, 3 parts of cicada slough, 5 parts of rhodiola root, 1 part of balloonflower root,
2 parts of rhizome of chuanxiong, 2 parts of ginseng, 1 part of cultivated land.
It is further preferred that the Radix Astragali is astragalus root.
The pharmaceutical composition of the present invention, can be prepared into emplastrum using existing method.
The present invention also provides use of the pharmaceutical composition of facial paralysis of the present invention in facial palsy correcting emplastrum is prepared
On the way.
Preferably, the facial palsy correcting emplastrum is sticked with facial paralysis by carrying out drawing to double acupuncture points.It is of the present invention
Double acupuncture points refer to the combination of two at acupuncture point, Ru Quan Liao caves and Dicang point；Fragrant cave and Xiaguan point；Touwei point and yang white cave etc..
Drawing of the present invention sticks, and refers to when using emplastrum, be pulled to opposite direction, such as, face is right to the askew then patch in the left side
The face of side pulls to the right.The emplastrum of the present invention, according to different syndrome type, Different Acupoint can be combined by acupuncture point combination of two
Carry out drawing to stick, reach the double effectses for the treatment of disease and relief of symptoms.
Compared with prior art, the present invention has the advantages that：
The externally-applied medicinal composition of the present invention, there is the effect of nourishing qi and blood, disperse blood stasis and dredge collateral, expelling wind and clearing away cold, to facial paralysis gas
Blood deficiency folder chill disease has good therapeutic effect.
The externally-applied medicinal composition of the present invention, is administered, facial palsy correcting emplastrum is administered to part, therefore by the way of external application
Local organization drug concentration gives full play to Chinese medicine effect, drug effect plays rapidly, evident in efficacy apparently higher than haemoconcentration.
The pharmaceutical composition of the present invention, is liniment, can reduce the secondary work of poison on the premise of therapeutic effect is ensured
With, and allergy is not easy, securely and reliably, it is wide to be applicable crowd's scope.
Embodiment
The externally-applied medicinal composition of facial paralysis of the present invention, its active component by following parts by weight Chinese medicine or Chinese medicine
Extract solution is prepared：5~7 parts of Radix Angelicae Sinensis, 5~7 parts of the Radix Astragali, 1~3 part of scorpio, 1~3 part of centipede, 2~4 parts of stiff silkworm, earthworm 2~
4 parts, 1~3 part of long-noded pit viper, 2~4 parts of cicada slough.
The pharmaceutical composition of the present invention, on the basis of existing endo-medicine, adds long-noded pit viper, you can not reducing treatment
On the basis of effect, endo-medicine is changed to external application, reduces the toxic side effect of medicine.
Long-noded pit viper is that drying for Viperidae animal point kiss Pallas pit viper (long-noded pit viper) is all.With wind-dispelling, dredging collateral, only the effect of convulsion.
The present inventor has found under study for action, if existing pharmaceutical composition is directly used in into external application, it will greatly reduces
Curative effect, and after adding long-noded pit viper, it can not only improve the therapeutic effect of liniment, moreover it is possible to effectively reduce liniment
Caused phenomena of cutaneous irritation.
Preferably, its active component is prepared by the Chinese medicine or Chinese medicine extract solution of following parts by weight：7 parts of Radix Angelicae Sinensis,
5 parts of the Radix Astragali, 2 parts of scorpio, 1 part of centipede, 3 parts of stiff silkworm, 4 parts of earthworm, 1 part of long-noded pit viper, 3 parts of cicada slough.
It is further preferred that the Radix Astragali is astragalus root.
The pharmaceutical composition of the present invention is external used medicine, has the effect of promoting blood circulation and removing obstruction in channels, QI invigorating Wen Yang, expelling wind and clearing away cold, is led to
Cross and apply the medicine, the symptom for carrying out facial paralysis can be improved.
Studied by Long-term clinical, the present invention also provides facial paralysis effect more significant externally-applied medicinal composition, upper
State and with the addition of rhodiola root, balloonflower root, rhizome of chuanxiong, ginseng and cultivated land on the basis of pharmaceutical composition.
The active component of the pharmaceutical composition is prepared by the Chinese medicine or Chinese medicine extract solution of following parts by weight：Radix Angelicae Sinensis
5~7 parts, 5~7 parts of the Radix Astragali, 1~3 part of scorpio, 1~3 part of centipede, 2~4 parts of stiff silkworm, 2~4 parts of earthworm, 1~3 part of long-noded pit viper, cicada
Slough off 2~4 parts, 5~7 parts of rhodiola root, 1~2 part of balloonflower root, 2~4 parts of rhizome of chuanxiong, 1~3 part of ginseng, 1~3 part of cultivated land.
Preferably, its active component is prepared by the Chinese medicine or Chinese medicine extract solution of following parts by weight：7 parts of Radix Angelicae Sinensis,
5 parts of the Radix Astragali, 2 parts of scorpio, 1 part of centipede, 3 parts of stiff silkworm, 4 parts of earthworm, 1 part of long-noded pit viper, 3 parts of cicada slough, 5 parts of rhodiola root, 1 part of balloonflower root,
2 parts of rhizome of chuanxiong, 2 parts of ginseng, 1 part of cultivated land.
It is further preferred that the Radix Astragali is astragalus root.
The present invention also provides use of the pharmaceutical composition of facial paralysis of the present invention in facial palsy correcting emplastrum is prepared
On the way.
The pharmaceutical composition of the present invention, can be prepared into emplastrum using existing method.Preferably, such as lower section can be used
Method：Chinese medicine after Processing methods is weighed by required weight, crushed No. six sieves, it is equal then to add the mixing of 1% host material
It is even, paste is made, is coated with non-woven fabrics back sheet uniformly, along with plastic sheeting lid lining, after pressing, cuts packaging, i.e.,
It can obtain facial palsy correcting emplastrum.The host material is mainly made up of sticker, NMF, filler etc., is existing matrix
Material.
Preferably, the facial palsy correcting emplastrum is sticked with facial paralysis by carrying out drawing to double acupuncture points.It is of the present invention
Double acupuncture points refer to the combination of two at acupuncture point, Ru Quan Liao caves and Dicang point；Fragrant cave and Xiaguan point；Touwei point and yang white cave etc..
Drawing of the present invention sticks, and refers to when using emplastrum, be pulled to opposite direction, such as, face is right to the askew then patch in the left side
The face of side pulls to the right.The emplastrum of the present invention, according to different syndrome type, Different Acupoint can be combined by acupuncture point combination of two
Carry out drawing to stick, reach the double effectses for the treatment of disease and relief of symptoms.
The embodiment of the present invention is further described with reference to embodiment, therefore not limited the present invention
System is among described scope of embodiments.
Embodiment 1
Facial palsy correcting emplastrum, its active component are made up of the medicine of following parts by weight：7 parts of Radix Angelicae Sinensis, 5 parts of the Radix Astragali, scorpio 2
Part, 1 part of centipede, 3 parts of stiff silkworm, 4 parts of earthworm, 1 part of long-noded pit viper, 3 parts of cicada slough.
Radix Angelicae Sinensis after Processing methods, the Radix Astragali, scorpio, centipede, stiff silkworm, earthworm, long-noded pit viper and cicada slough are claimed by required weight
Take, crushed No. six sieves, then add 1% host material and be well mixed, paste is made, be coated with non-woven fabrics back sheet equal
It is even, along with plastic sheeting lid lining, after pressing, packaging is cut, obtains leading positive patch 1.
Embodiment 2
Facial palsy correcting emplastrum, its active component are made up of the medicine of following parts by weight：7 parts of Radix Angelicae Sinensis, 5 parts of the Radix Astragali, scorpio 2
Part, 1 part of centipede, 3 parts of stiff silkworm, 4 parts of earthworm, 1 part of long-noded pit viper, 3 parts of cicada slough, 5 parts of rhodiola root, 1 part of balloonflower root, 2 parts of rhizome of chuanxiong, ginseng 2
Part, 1 part of cultivated land.
By the Radix Angelicae Sinensis after Processing methods, the Radix Astragali, scorpio, centipede, stiff silkworm, earthworm, long-noded pit viper, cicada slough, rhodiola root, balloonflower root,
Rhizome of chuanxiong, ginseng and cultivated land are weighed by required weight, be crushed No. six sieves, are then added 1% host material and be well mixed, cream is made
Agent, it is coated with non-woven fabrics back sheet uniformly, along with plastic sheeting lid lining, after pressing, cuts packaging, obtain leading positive patch 2.
Comparative example 1
Facial palsy correcting emplastrum, its active component are made up of the medicine of following parts by weight：7 parts of Radix Angelicae Sinensis, 5 parts of the Radix Astragali, scorpio 2
Part, 1 part of centipede, 3 parts of stiff silkworm, 4 parts of earthworm, 3 parts of cicada slough.
Radix Angelicae Sinensis after Processing methods, the Radix Astragali, scorpio, centipede, stiff silkworm, earthworm and cicada slough are weighed by required weight, crushed
No. six sieves are crossed, 1% host material is then added and is well mixed, paste is made, is coated with uniformly, adds on non-woven fabrics back sheet
Plastic sheeting lid lining, after pressing, packaging is cut, obtain leading positive patch 3.
Comparative example 2
Facial palsy correcting emplastrum, its active component are made up of the medicine of following parts by weight：7 parts of Radix Angelicae Sinensis, 5 parts of the Radix Astragali, scorpio 2
Part, 1 part of centipede, 3 parts of stiff silkworm, 4 parts of earthworm, 3 parts of cicada slough, 5 parts of rhodiola root, 1 part of balloonflower root, 2 parts of rhizome of chuanxiong, 2 parts of ginseng, 1 part of cultivated land.
By the Radix Angelicae Sinensis after Processing methods, the Radix Astragali, scorpio, centipede, stiff silkworm, earthworm, cicada slough, rhodiola root, balloonflower root, rhizome of chuanxiong, people
Ginseng and cultivated land are weighed by required weight, be crushed No. six sieves, are then added 1% host material and be well mixed, paste is made, in nothing
It is uniform to spin coating on cloth back sheet, along with plastic sheeting lid lining, after pressing, cuts packaging, obtains leading positive patch 4.
Test example 1
Facial palsy correcting paste is prepared in the embodiment of the present invention and comparative example and is used for facial paralysis, by Different Acupoint
Combination carries out drawing and sticked, and removes emplastrum within every eight hours, stops eight hours, then pastes once, twice a day；The course for the treatment of is ten days.It is treated
Effect is shown in Table 1.
Table 1
Claims (8)
1. the externally-applied medicinal composition of facial paralysis, it is characterised in that its active component by following parts by weight Chinese medicine or in
Herbal extract is prepared：5~7 parts of Radix Angelicae Sinensis, 5~7 parts of the Radix Astragali, 1~3 part of scorpio, 1~3 part of centipede, 2~4 parts of stiff silkworm,
2~4 parts of dragon, 1~3 part of long-noded pit viper, 2~4 parts of cicada slough.
2. the externally-applied medicinal composition of facial paralysis according to claim 1, it is characterised in that its active component is by following
The Chinese medicine of parts by weight is prepared：7 parts of Radix Angelicae Sinensis, 5 parts of the Radix Astragali, 2 parts of scorpio, 1 part of centipede, 3 parts of stiff silkworm, 4 parts of earthworm, long-noded pit viper
1 part, 3 parts of cicada slough.
3. the externally-applied medicinal composition of facial paralysis according to claim 1 or 2, it is characterised in that：The Radix Astragali is to process
The Radix Astragali.
4. the externally-applied medicinal composition of facial paralysis, it is characterised in that its active component by following parts by weight Chinese medicine or in
Herbal extract is prepared：5~7 parts of Radix Angelicae Sinensis, 5~7 parts of the Radix Astragali, 1~3 part of scorpio, 1~3 part of centipede, 2~4 parts of stiff silkworm,
2~4 parts of dragon, 1~3 part of long-noded pit viper, 2~4 parts of cicada slough, 5~7 parts of rhodiola root, 1~2 part of balloonflower root, 2~4 parts of rhizome of chuanxiong, ginseng 1~3
Part, 1~3 part of cultivated land.
5. the externally-applied medicinal composition of facial paralysis according to claim 4, it is characterised in that its active component is by following
The Chinese medicine or Chinese medicine extract solution of parts by weight are prepared：7 parts of Radix Angelicae Sinensis, 5 parts of the Radix Astragali, 2 parts of scorpio, 1 part of centipede, 3 parts of stiff silkworm,
4 parts of earthworm, 1 part of long-noded pit viper, 3 parts of cicada slough, 5 parts of rhodiola root, 1 part of balloonflower root, 2 parts of rhizome of chuanxiong, 2 parts of ginseng, 1 part of cultivated land.
6. the externally-applied medicinal composition of the facial paralysis according to claim 4 or 5, it is characterised in that：The Radix Astragali is to process
The Radix Astragali.
7. purposes of the pharmaceutical composition of the facial paralysis described in any one of claim 1~6 in facial palsy correcting emplastrum is prepared.
8. purposes of the pharmaceutical composition of facial paralysis according to claim 7 in facial palsy correcting emplastrum is prepared, it is special
Sign is：The facial palsy correcting emplastrum is sticked with facial paralysis by carrying out drawing to double acupuncture points.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711052088.1A CN107550974A (en) | 2017-10-30 | 2017-10-30 | Externally-applied medicinal composition of facial paralysis and application thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711052088.1A CN107550974A (en) | 2017-10-30 | 2017-10-30 | Externally-applied medicinal composition of facial paralysis and application thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109223990A (en) * | 2018-11-21 | 2019-01-18 | 浙江公望堂生物科技有限公司 | Pass through the Chinese medicine composition and preparation method thereof of ear acupoint application treatment facial paralysis |
| CN110664911A (en) * | 2019-10-23 | 2020-01-10 | 德州学院 | Traditional Chinese medicine cataplasm for treating facial paralysis and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991638A (en) * | 2010-11-26 | 2011-03-30 | 潘畅 | Medicine composition for treating facial paralysis as well as preparation method and application thereof |
| CN105616480A (en) * | 2016-03-08 | 2016-06-01 | 昆明市中医医院 | Facial paralysis aright-pulling mask and preparation method thereof |
-
2017
- 2017-10-30 CN CN201711052088.1A patent/CN107550974A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101991638A (en) * | 2010-11-26 | 2011-03-30 | 潘畅 | Medicine composition for treating facial paralysis as well as preparation method and application thereof |
| CN105616480A (en) * | 2016-03-08 | 2016-06-01 | 昆明市中医医院 | Facial paralysis aright-pulling mask and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 刘志勇: "面瘫的中医综合治疗", 《基层医学论坛》 * |
| 韩浩等: "正面汤治疗面瘫36例", 《陕西中医》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109223990A (en) * | 2018-11-21 | 2019-01-18 | 浙江公望堂生物科技有限公司 | Pass through the Chinese medicine composition and preparation method thereof of ear acupoint application treatment facial paralysis |
| CN110664911A (en) * | 2019-10-23 | 2020-01-10 | 德州学院 | Traditional Chinese medicine cataplasm for treating facial paralysis and preparation method thereof |
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Application publication date: 20180109 |