CN107532214B - 用于败血症诊断的方法 - Google Patents

用于败血症诊断的方法 Download PDF

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CN107532214B
CN107532214B CN201680023601.1A CN201680023601A CN107532214B CN 107532214 B CN107532214 B CN 107532214B CN 201680023601 A CN201680023601 A CN 201680023601A CN 107532214 B CN107532214 B CN 107532214B
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sepsis
infection
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polynucleotide
biomarkers
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CN107532214A (zh
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普尔威施·卡特里
蒂莫西·E·斯威尼
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Leland Stanford Junior University
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/20—Polymerase chain reaction [PCR]; Primer or probe design; Probe optimisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Spectroscopy & Molecular Physics (AREA)
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  • Bioinformatics & Computational Biology (AREA)
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  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
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  • General Engineering & Computer Science (AREA)
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  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201680023601.1A 2015-03-12 2016-03-12 用于败血症诊断的方法 Active CN107532214B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562132293P 2015-03-12 2015-03-12
US62/132,293 2015-03-12
PCT/US2016/022233 WO2016145426A1 (en) 2015-03-12 2016-03-12 Methods for diagnosis of sepsis

Publications (2)

Publication Number Publication Date
CN107532214A CN107532214A (zh) 2018-01-02
CN107532214B true CN107532214B (zh) 2021-08-31

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US (3) US10533224B2 (enExample)
EP (1) EP3268499B1 (enExample)
JP (3) JP6995622B2 (enExample)
CN (1) CN107532214B (enExample)
AU (2) AU2016228508A1 (enExample)
CA (1) CA2977422A1 (enExample)
IL (3) IL297699A (enExample)
WO (1) WO2016145426A1 (enExample)

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WO2015135071A1 (en) 2014-03-14 2015-09-17 Hancock Robert E W Diagnostic for sepsis
GB201616557D0 (en) * 2016-09-29 2016-11-16 Secretary Of State For Health The Assay for distinguishing between sepsis and systemic inflammatory response syndrome
US20190354814A1 (en) * 2017-01-08 2019-11-21 Henry M. Jackson Foundation For The Advancement Of Military Medicine Systems and methods for using supervised learning to predict subject-specific bacteremia outcomes
EP3477305A1 (en) 2017-10-25 2019-05-01 Universität Heidelberg Delta-like ligand 1 for diagnosing severe infections
US10433191B2 (en) * 2018-01-08 2019-10-01 Cisco Technology, Inc. Channel management in a virtual access point (VAP)
US11538566B2 (en) * 2018-05-23 2022-12-27 Beckman Coulter, Inc. Sample analysis with test determination based on identified condition
US20210369797A1 (en) * 2018-10-04 2021-12-02 Western Sydney Local Health District Bacteriophage treatment and reduction in inflammatory response
WO2020096984A1 (en) * 2018-11-05 2020-05-14 Institute For Systems Biology Sepsis biomarker panels and methods of use
CN113785074A (zh) 2019-03-25 2021-12-10 斯坦福大学托管董事会 用于诊断细菌感染与病毒感染的特征
US11104946B2 (en) 2019-04-23 2021-08-31 Inflammatix, Inc. DNA sequences related to diagnosis and treatment of systemic inflammatory response syndrome
CN112391460A (zh) * 2019-08-19 2021-02-23 四川生美思达生物科技有限公司 用于脓毒症的生物标志物组及脓毒症判断方法和试剂盒
CA3098079C (en) * 2019-12-13 2023-06-20 Autonomous Medical Devices Inc. Apparatus and method for point-of-care, rapid, field-deployable diagnostic testing of covid-19, viruses, antibodies and markers
KR102281512B1 (ko) * 2020-03-26 2021-07-23 경북대학교 산학협력단 TGFBIp의 아세틸화 수준을 측정하는 제제를 포함하는 염증성 질환 진단용 조성물
JP2023525489A (ja) * 2020-04-29 2023-06-16 インフラマティックス インコーポレイテッド ウイルス感染症を有する対象の死亡率リスクの決定
CN111563891B (zh) * 2020-05-09 2023-09-26 吾征智能技术(北京)有限公司 基于颜色认知的疾病预测系统
FR3112207A1 (fr) * 2020-07-06 2022-01-07 bioMérieux Procédé pour déterminer le risque de survenue d’une infection associée aux soins chez un patient
FR3112209A1 (fr) * 2020-07-06 2022-01-07 bioMérieux Procédé pour déterminer le risque de complication chez un patient
FR3112211A1 (fr) * 2020-07-06 2022-01-07 bioMérieux Procédé pour déterminer le risque de survenue d’une infection associée aux soins chez un patient
CN111721941B (zh) * 2020-07-17 2023-08-25 南方科技大学 一种用于判断脓毒症感染情况的装置及其应用
WO2022066963A1 (en) * 2020-09-25 2022-03-31 The Board Of Trustees Of The Leland Stanford Junior University Method for determining a virally-infected subject's risk of developing severe symptoms
JP2024520049A (ja) 2021-05-25 2024-05-21 ザ ユニヴァーシティ オブ ブリティッシュ コロンビア 敗血症のエンドタイプおよび／または重症度の診断
WO2023023125A1 (en) * 2021-08-17 2023-02-23 Predigen, Inc. Methods for characterizing infections and methods for developing tests for the same
CN115295151B (zh) * 2022-09-01 2024-12-27 中山大学附属第三医院 脓毒症预测系统、预测模型构建方法及系统、试剂盒
CN120809235A (zh) * 2025-09-04 2025-10-17 华中科技大学同济医学院附属同济医院 一种基于人工智能的多发伤患者脓毒症的早期预警方法

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JP2023138990A (ja) 2023-10-03
IL286853A (en) 2021-10-31
JP6995622B2 (ja) 2022-01-14
EP3268499A1 (en) 2018-01-17
EP3268499A4 (en) 2018-09-05
JP2022058359A (ja) 2022-04-12
IL297699A (en) 2022-12-01
IL254229A0 (en) 2017-10-31
AU2022203348A1 (en) 2022-06-09
US20200131577A1 (en) 2020-04-30
US20180291449A1 (en) 2018-10-11
US20230227911A1 (en) 2023-07-20
IL286853B (en) 2022-12-01
AU2016228508A1 (en) 2017-09-07
WO2016145426A1 (en) 2016-09-15
IL254229B (en) 2021-10-31
US10533224B2 (en) 2020-01-14
EP3268499B1 (en) 2020-05-13
JP2018514189A (ja) 2018-06-07
WO2016145426A8 (en) 2017-04-06
CA2977422A1 (en) 2016-09-15
CN107532214A (zh) 2018-01-02
IL286853B2 (en) 2023-04-01

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