CN107496818A - It is a kind of to be used to treat pill medicine of gastric and duodenal ulcer and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to a kind of pill medicine for being used to treat gastric and duodenal ulcer be provided according to the understanding mechanism of Chinese traditional treatment gastric and duodenal ulcer, each component and its mass parts ratio of the medicine are as follows：50~160g of the root of Dahurain angelica, 50~100g of cuttle bone, 30~120g of bletilla, 60~150g of the bighead atractylodes rhizome, 30~70g of Amomum cardamomum, 30~100g of bulbus fritillariae cirrhosae, 50~160g of radix scutellariae, 30~150g of golden cypress, 30~100g of corydalis tuber, rhizoma cyperi（Vinegar system）50~120g, 30~100g of dried orange peel, 20~100g of asarum, 60~160g of jujube, 30~100g of pseudo-ginseng, medicine provided by the invention are a good Chinese prescriptions.

Description

It is a kind of to be used to treat pill medicine of gastric and duodenal ulcer and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for being used to treat gastric and duodenal ulcer The field of thing, the pill medicine particularly used for gastric and duodenal ulcer patient and preparation method thereof.

Background technology

Shown according to related data：Gastric and duodenal ulcer is extremely common disease.Its topical manifestations are to be located at stomach And the limitation circle of duodenal wall or the defect of ellipse.Patient has the diseases such as periodicity upper abdomen pain, acid reflux, belch Shape.The easy recurrent exerbation of this disease, in chronic process.There is 2 kinds of gastric and duodenal ulcer.Duodenal ulcer is common compared with gastric ulcer, The former accounts for 70% according to statistics, and the latter accounts for 25%, and both and the combined Peptic Ulcer deposited account for 5%.

Clinical manifestation：

The main clinical manifestation of duodenal ulcer is upper abdomen pain, can be dull pain, cusalgia, distending pain or severe pain, can also show For the secret anguish discomfort only in starvation.Typical person shows as rest pain under slight or moderate xiphoid-process, can be by antiacid or feed Alleviate.The pain that clinically there are about 2/3 is in rhythmicity：It is early to start epigastric pain occur within postprandial 1~3 hour, if do not taken medicine or feeding Just alleviate after then continuing to lunch.2~4 hours and pain, must also have meal to alleviate after food.About half patient has pain at midnight, disease People can often wake up bitterly.Rhythmicity pain continues several weeks mostly, with the several months is alleviated, can repeated.

So, it is this area skill with regard to how to find a kind of Chinese medicine composition that can effectively treat gastric and duodenal ulcer The problem of art personnel are urgently to be resolved.

The content of the invention

With the continuous development of China's traditional Chinese medicine, on treatment gastric and duodenal ulcer, people gradually recognize The advantages of Chinese traditional treatment gastric and duodenal ulcer, and over the course for the treatment of good effect, that quick, toxic side effect is small etc. is excellent Gesture, for the present situation of existing western medical treatment gastric and duodenal ulcer, the purpose of the present invention is to be that providing one kind is used to treat The pill medicine of gastric and duodenal ulcer, to solve the problems, such as that gastric and duodenal ulcer patient gets well early.The medicine Thing is using common Chinese medicine as raw material, by selecting rational medicine and its mass parts ratio, can effectively treat above-mentioned stomach and 12 Duodenalulcer.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：There is provided a kind of for treating stomach and ten Pill medicine of two Duodenalulcers and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：

50~160g of the root of Dahurain angelica, 50~100g of cuttle bone, 30~120g of bletilla, 60~150g of the bighead atractylodes rhizome, 30~70g of Amomum cardamomum, tendril-leaved fritillary bulb 30~100g of mother, 50~160g of radix scutellariae, 30~150g of golden cypress, 30~100g of corydalis tuber, rhizoma cyperi（Vinegar system）50~120g, dried orange peel 30 ~100g, 20~100g of asarum, 60~160g of jujube, 30~100g of pseudo-ginseng, auxiliary material：Appropriate starch.

It is a kind of to be used to treat pill medicine of gastric and duodenal ulcer and preparation method thereof, it is characterised in that the medicine The each component and its mass parts of thing are than as follows：

58~130g of the root of Dahurain angelica, 58~90g of cuttle bone, 38~105g of bletilla, 70~130g of the bighead atractylodes rhizome, 38~60g of Amomum cardamomum, bulbus fritillariae cirrhosae 38~90g, 58~130g of radix scutellariae, 38~130g of golden cypress, 38~90g of corydalis tuber, rhizoma cyperi（Vinegar system）58~105g, dried orange peel 38~ 90g, 26~90g of asarum, 70~130g of jujube, 36~90g of pseudo-ginseng, auxiliary material：Appropriate starch.

It is a kind of to be used to treat pill medicine of gastric and duodenal ulcer and preparation method thereof, it is characterised in that the medicine The each component and its mass parts of thing are than as follows：

Root of Dahurain angelica 115g, cuttle bone 80g, bletilla 95g, bighead atractylodes rhizome 115g, Amomum cardamomum 50g, bulbus fritillariae cirrhosae 80g, radix scutellariae 115g, golden cypress 115g, corydalis tuber 80g, rhizoma cyperi（Vinegar system）95g, dried orange peel 80g, asarum 80g, jujube 115g, pseudo-ginseng 80g, auxiliary material：Appropriate starch.

It is a kind of to be used to treat pill medicine of gastric and duodenal ulcer and preparation method thereof, it is characterised in that the side Method comprises the following steps to be prepared：

A, after above-mentioned raw materials Chinese medicine being picked impurity, dust and dried, it is stand-by to be ground into superfine end according to mass parts ratio；

B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch sieving, it is put into medicine device Middle mixing is mixed, is then prepared into water-bindered pill agent（The granularity of its water-bindered pill is：3.9mm~4.0mm）, and then dry, sterilization, packing is close Envelope.

It is a kind of to be used to treat pill medicine of gastric and duodenal ulcer and preparation method thereof, it is characterised in that the clothes It is with method：By the water pill medicine prepared three times a day to take, once a dose in the morning, afternoon and evening, and dosage 6g/time, after meal Warm water delivery service.30 days are a course for the treatment of, and 3~5.5 courses for the treatment of of taking medicine, gastric and duodenal ulcer symptom is clearly better or thoroughly Recovery from illness, follow-up more than 2 years, no relapse.

Each raw material Chinese medicine in prescription of the present invention has detailed in Chinese Pharmacopoeia, Chinese dictionary and its China's book on Chinese herbal medicine Record.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

The root of Dahurain angelica, nature and flavor：Warm-natured, acrid flavour, gas fragrance, slight bitter, have the effect of wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving, for controlling Treat headache, toothache, nasosinusitis, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, pruitus；

Cuttle bone, nature and flavor：Nature and flavor：It is salty, puckery, warm, there is the effect of astringing to arrest bleeding, relieving leukorrhea by astringents, relieving haperacidity, sore, for treating Stomachache acid regurgitation, hematemesis and epistaxis, uterine bleeding are had blood in stool, emission and spermatorrhea, leukorrhea with reddish discharge, canker, control the more pus of bleeding due to trauma, sore outside；

Bletilla, nature and flavor：It is bitter, sweet, puckery, cold, have astringing to arrest bleeding, detumescence and promoting granulation the effect of, for treat spitting of blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, Have blood in stool, traumatism and bleeding, ulcerative carbuncle pyogenic infections, scald burn, the disease such as rhagadia manus et pedis, anal fissure；

The bighead atractylodes rhizome, nature and flavor：It is bitter, sweet, warm-natured, have strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, it is antiabortive the effect of, for treating temper The few abdominal distension of weakness, spiritlessness and weakness, deficiency of food, big loose stool are thin, fluid retention stagnating in the interior, difficult urination, oedema, phlegmatic vertigo, warm numbness are ached, gas The diseases such as empty spontaneous perspiration, fetal irritability；

Amomum cardamomum, nature and flavor：It is acrid flavour, warm-natured, there is the effect of dampness elimination promoting the circulation of qi, warming middle energizer to arrest vomiting, appetite-stimulating indigestion-relieving, for treating dampness gas Stagnant, incoordination between the spleen and the stomach, abdominal fullness and distention, do not feel like eating, damp-warm syndrome from the beginning of, not hungry, gastrofrigid vomiting uncomfortable in chest, dyspepsia；

Bulbus fritillariae cirrhosae, nature and flavor：It is bitter, sweet, be slightly cold, there is the effect of clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, for treating lung-heat type cough, dry cough Few phlegm, deficiency of Yin overstrain cough, cough up sputum streaked with blood；

Radix scutellariae, nature and flavor：It is bitter, cold, have rush down excess fire, except it is damp and hot, hemostasis, it is antiabortive the effect of, for treating high fever polydipsia, lung heat cough Cough, damp-heat dysentery, jaundice, heat gonorrhea, tell, be defeated in battle, collapsing, leaking, red eye, swell pain, fetal irritability, carbuncle swells furunculosis；

Golden cypress, nature and flavor：It is bitter, cold, there is the effect of heat-clearing and damp-drying drug, purging intense heat, except steaming, detoxification sore treatment, for treating damp-heat dysentery, Huang Subcutaneous ulcer, band under, heat gonorrhea, tinea pedis, impotence { warding off }, hectic fever due to yin labor heat, night sweat, seminal emission, sore swollen toxin, eczema itch, stir-baked CORTEX PHELLODENDRI with salt solution nourishing Yin and falling fire, For fire excess from yin deficiency, night sweat hectic fever due to yin；

Corydalis tuber, nature and flavor：Acrid, bitter, warm, there are promoting blood circulation, sharp gas, analgesic, for treating chest side of body, epigastric pain, warp Close dysmenorrhoea, postpartum stasis, tumbling and swelling；

Rhizoma cyperi（Vinegar system）, nature and flavor：Acrid flavour, be slightly cold, it is nontoxic, have regulating the flow of vital energy Xie Yu, menstruction regulating and pain relieving, it is antiabortive the effect of, for treating The distending pain in hypochondrium, breast swelling, hernia pain, irregular menstruation, epigastric abdominal fullness pain, belch acid regurgitation, evil of vomitting, dysmenorrhea, uterine bleeding Under band, the disease such as fetal irritability；

Dried orange peel, nature and flavor：It is bitter, pungent, warm, have regulating qi-flowing for strengthening spleen, it is eliminating dampness and eliminating phlegm the effect of, for treat chest gastral cavity turgor, deficiency of food vomit and diarrhoea, Coughing with a lot of sputum；

Asarum, nature and flavor：It is pungent, warm, there is wind-dispelling, cold dispelling, water-filling, the effect of having one's ideas straightened out, for treat air-cooled headache, nasosinusitis, dentalgia, Phlegm and retained fluid cough is inverse, arthralgia pain due to rheumatism；

Jujube, nature and flavor：It is sweet, warm, fruit（Jujube）：The effect of with tonifying middle-Jiao and Qi, nourishing blood and tranquilization, for treating spleen eating less, weary Power loose stool, hysteria of womam；Bark：Anti-inflammatory, hemostasis, antidiarrheal, for tracheitis, enteritis, dysentery, uterine bleeding, traumatism and bleeding is controlled in external application, Root：Promoting the circulation of qi, promoting blood circulation, menstruation regulating, for irregular menstruation, it is red collapse, the disease such as leukorrhea；

Pseudo-ginseng, nature and flavor：Sweet, bitter, tepor, have hemostasis, dissipate the stasis of blood, be fixed logical, repellent the effect of, for treat knife wound, bullet wound and Fall that to flutter traumatic bleeding more than, can control again haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, hematuria, bloody flux, metrorrhagia, incessant menorrhea, postpartum extravesated blood not under, blood Dizzy, blood pain, the logical swollen, beast of hot eyes sting snakebite.

Medicine of the present invention is the principle based on Chinese traditional treatment gastric and duodenal ulcer, from according to gastric and duodenal ulcer Pathomechanism and pharmacological action think：With regard to gastric and duodenal ulcer, each raw material Chinese medicine in medicine provided by the present invention Drug effect is played altogether, has good effect to above-mentioned disease.

Embodiment

A kind of Chinese medicine preparation for being itd is proposed aiming at the treatment of above-mentioned gastric and duodenal ulcer of the present invention, use this match somebody with somebody The medicine effect just prepared is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.With reference to this hair Bright embodiment is described in further detail：

Embodiment 1：

It is a kind of to be used to treat the pill medicine of gastric and duodenal ulcer, it is characterised in that each component of the medicine and its Mass parts are than as follows：

Root of Dahurain angelica 115g, cuttle bone 80g, bletilla 95g, bighead atractylodes rhizome 115g, Amomum cardamomum 50g, bulbus fritillariae cirrhosae 80g, radix scutellariae 115g, golden cypress 115g, corydalis tuber 80g, rhizoma cyperi（Vinegar system）95g, dried orange peel 80g, asarum 80g, jujube 115g, pseudo-ginseng 80g, auxiliary material：Appropriate starch.

Embodiment 2：

It is a kind of to be used to treat the pill medicine of gastric and duodenal ulcer, it is characterised in that each component of the medicine and its Mass parts are than as follows：

Root of Dahurain angelica 130g, cuttle bone 90g, bletilla 105g, bighead atractylodes rhizome 130g, Amomum cardamomum 60g, bulbus fritillariae cirrhosae 90g, radix scutellariae 130g, golden cypress 130g, corydalis tuber 90g, rhizoma cyperi（Vinegar system）105g, dried orange peel 90g, asarum 90g, jujube 130g, pseudo-ginseng 90g, auxiliary material：Appropriate starch.

Embodiment 3：

It is a kind of to be used to treat the pill medicine of gastric and duodenal ulcer, it is characterised in that each component of the medicine and its Mass parts are than as follows：

Root of Dahurain angelica 160g, cuttle bone 100g, bletilla 120g, bighead atractylodes rhizome 150g, Amomum cardamomum 70g, bulbus fritillariae cirrhosae 100g, radix scutellariae 160g, golden cypress 150g, corydalis tuber 100g, rhizoma cyperi（Vinegar system）120g, dried orange peel 100g, asarum 100g, jujube 160g, pseudo-ginseng 100g, auxiliary material：Starch In right amount.

Model case

Through clinical conditions gastric and duodenal ulcer patient totally 1230, the age is 635 of more than 48 years old, only 595 Example is less than 48 years old.780 to be fully recovered in 1230 patients, effective 419, invalid 31.Total effective rate is up to 97.5%.

Claims (3)

1. a kind of be used to treat the pill medicine of gastric and duodenal ulcer, it is characterised in that each component of the medicine and Its mass parts is than as follows：

50~160g of the root of Dahurain angelica, 50~100g of cuttle bone, 30~120g of bletilla, 60~150g of the bighead atractylodes rhizome, 30~70g of Amomum cardamomum, tendril-leaved fritillary bulb 30~100g of mother, 50~160g of radix scutellariae, 30~150g of golden cypress, 30~100g of corydalis tuber, rhizoma cyperi（Vinegar system）50~120g, dried orange peel 30 ~100g, 20~100g of asarum, 60~160g of jujube, 30~100g of pseudo-ginseng, auxiliary material：Appropriate starch.

2. the pill medicine according to claim 1 for being used to treat gastric and duodenal ulcer, it is characterised in that the medicine The each component and its mass parts of thing are than as follows：

58~130g of the root of Dahurain angelica, 58~90g of cuttle bone, 38~105g of bletilla, 70~130g of the bighead atractylodes rhizome, 38~60g of Amomum cardamomum, bulbus fritillariae cirrhosae 38~90g, 58~130g of radix scutellariae, 38~130g of golden cypress, 38~90g of corydalis tuber, rhizoma cyperi（Vinegar system）58~105g, dried orange peel 38~ 90g, 26~90g of asarum, 70~130g of jujube, 36~90g of pseudo-ginseng, auxiliary material：Appropriate starch.

3. the pill medicine for being used to treat gastric and duodenal ulcer according to claim 1 to 2, it is characterised in that institute The each component and its mass parts of medicine are stated than as follows：

Root of Dahurain angelica 115g, cuttle bone 80g, bletilla 95g, bighead atractylodes rhizome 115g, Amomum cardamomum 50g, bulbus fritillariae cirrhosae 80g, radix scutellariae 115g, golden cypress 115g, corydalis tuber 80g, rhizoma cyperi（Vinegar system）95g, dried orange peel 80g, asarum 80g, jujube 115g, pseudo-ginseng 80g, auxiliary material：Appropriate starch.