CN107469003A - A kind of endo-medicine and preparation method for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer - Google Patents

A kind of endo-medicine and preparation method for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer Download PDF

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CN107469003A
CN107469003A CN201710798367.6A CN201710798367A CN107469003A CN 107469003 A CN107469003 A CN 107469003A CN 201710798367 A CN201710798367 A CN 201710798367A CN 107469003 A CN107469003 A CN 107469003A
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medicine
stagnation
root
thyroid cancer
blood stasis
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罗兴贵
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Chengdu Xing More Biotechnology LLC
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Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of endo-medicine for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer provided according to the understanding mechanism of the postoperative syndrome of qi stagnation and blood stasis of Chinese traditional treatment thyroid cancer, each component and its mass parts ratio of the medicine are as follows：250~500g of japanese aralia bark, 30~90g of radix bupleuri, 500~1000g of beechey fig leaf, 60~150g of decumbent corydalis tuber, 60~150g of hairyvein agrimony, 30~100g of rascal, 30~120g of curcuma zedoary, 150~250g of Alocasia ordora, 30~100g of edible tulip, 30~120g of Ligusticum wallichii, 50~150g of whorlleaf litse root, 100~160g of hedge glorybind root, 60~100g of rhizoma cyperi, 30~120g of honey-fried licorice root, 90~160g of selfheal, medicine provided by the invention are a good Chinese prescriptions.

Description

A kind of endo-medicine and preparation method for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer
Technical field
The invention belongs to field of traditional Chinese, and in particular to a kind of medicine for oral administration for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer Thing, the endo-medicine particularly used for the postoperative syndrome of qi stagnation and blood stasis patient of thyroid cancer and the field of preparation method.
Background technology
Motherland's medical science thinks：Thyroid cancer, thyroid cancer are clinical common a kind of neck malignant tumors, and the incidence of disease is at me State is just in the gesture of rising year by year.At present in Chinese population, the illness rate of thyroid nodule is 18.6%, wherein Malignant Nodules (i.e. thyroid cancer) accounts for 5%~10%, and histological type is broadly divided into papillary carcinoma, filter blocking cancer, undifferentiated carcinoma, cephaloma etc.. In addition to except diagnostic techniques, prosperity is improved increasingly, improper diet, excessive stress, radioactive ray irradiation may all lure for disease Cause.
Shape gland cancer is the malignant tumour of incidence of disease highest in current endocrine system disease, accounts for whole body malignant tumour 1%, women number is 2~3 times of male in patient groups.Recent epidemiology survey prompting, in multiple countries of the world The sick incidence of disease shows faster rising situation.Thyroid cancer is generally divided into papillary carcinoma, follicular cells cancer, undifferentiated Cancer, parafollicular cell cancer and thyroid lymphoma.Papillary carcinoma and filter blocking cancer belong to differentiated thyroid carcinoma together (DTC), its disease rates highest in thyroid cancer, up to 90%.
At present, the integration scenario of western medical treatment differentiated thyroid carcinoma：Operation radioiodine ablation hormone suppression therapy. Doctor trained in Western medicine also brings certain adverse reaction, such as while Radical Thyroidectomy is implemented：Treat this after being ill, marrow hemopoiesis Function is suppressed, and causes white blood cell, hemoglobin, decrease of platelet, it is difficult to recovers normal in a short time；Postoperative fatigue is weary Power, neck and shoulder part swelling is numb, shouting pain；Thyroid hormone suppresses emotional change after therapy, many situations such as uncomfortable in chest of having palpitation, serious shadow The quality of life of patient is rung.
So, a kind of Chinese medicine composition that can effectively treat the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer how is just found, is this The problem of art personnel are urgently to be resolved.
The content of the invention
With the continuous development of China's traditional Chinese medicine, on the treatment postoperative syndrome of qi stagnation and blood stasis of thyroid cancer, people are gradual The advantages of appreciating Chinese traditional treatment thyroid cancer postoperative syndrome of qi stagnation and blood stasis, and good effect, quick, malicious pair over the course for the treatment of The advantage such as small is acted on, for the present situation of the existing postoperative syndrome of qi stagnation and blood stasis of western medical treatment thyroid cancer, the purpose of the present invention is to be A kind of endo-medicine for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer is provided, to solve the postoperative syndrome of qi stagnation and blood stasis patient of thyroid cancer The problem of getting well early.The medicine be using common Chinese medicine as raw material, by selecting rational medicine and its mass parts ratio, The postoperative syndrome of qi stagnation and blood stasis of above-mentioned thyroid cancer can effectively be treated.
To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：One kind is provided and treats thyroid cancer art The endo-medicine and preparation method of syndrome of qi stagnation and blood stasis afterwards, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：
250~500g of japanese aralia bark, 30~90g of radix bupleuri, 500~1000g of beechey fig leaf, 60~150g of decumbent corydalis tuber, hairyvein agrimony 60~ 150g, 30~100g of rascal, 30~120g of curcuma zedoary, 150~250g of Alocasia ordora, 30~100g of edible tulip, 30~120g of Ligusticum wallichii, bruise Old 50~150g, 100~160g of hedge glorybind root, 60~100g of rhizoma cyperi, 30~120g of honey-fried licorice root, 90~160g of selfheal, auxiliary material：It is micro- Powder silica gel, microcrystalline cellulose and appropriate starch.
A kind of endo-medicine and preparation method for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer, it is characterised in that the medicine The each component and its mass parts of thing are than as follows：
280~420g of japanese aralia bark, 38~80g of radix bupleuri, 420~850g of beechey fig leaf, 70~130g of decumbent corydalis tuber, hairyvein agrimony 70~ 130g, 38~90g of rascal, 30~105g of curcuma zedoary, 180~220g of Alocasia ordora, 38~90g of edible tulip, 38~105g of Ligusticum wallichii, whorlleaf litse root 58~130g, 115~130g of hedge glorybind root, 70~90g of rhizoma cyperi, 38~105g of honey-fried licorice root, 100~130g of selfheal, auxiliary material：Micro mist Silica gel, microcrystalline cellulose and appropriate starch.
A kind of endo-medicine and preparation method for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer, it is characterised in that the medicine The each component and its mass parts of thing are than as follows：
Japanese aralia bark 360g, radix bupleuri 70g, beechey fig leaf 720g, decumbent corydalis tuber 115g, hairyvein agrimony 115g, rascal 80g, curcuma zedoary 95g, Alocasia ordora 200g, edible tulip 80g, Ligusticum wallichii 95g, whorlleaf litse root 115g, hedge glorybind root 118g, rhizoma cyperi 80g, honey-fried licorice root 95g, selfheal 115g, it is auxiliary Material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
A kind of endo-medicine and preparation method for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer, it is characterised in that the side Method comprises the following steps to be prepared：
A, after above-mentioned raw materials Chinese medicine being picked into impurity and dust, it is ground into according to mass parts than altogether（30~50 mesh）Graininess bag Decoct；
B, 1. the raw material Chinese medicine wrapped is put into cold boiling water and soaks 60min, then soaked medicine is put into marmite again, The cold boiling water for adding 8 times of raw material Chinese medicine weight carries out first time high heat decoction, when 18min is arrived in decoction, turns slow fire and boils 120min, leaching decoction；2. the cold boiling water for adding 7 times of raw material Chinese medicine weight in the dregs of a decoction again carries out second of high heat decoction, treat When decocting 15min, turn slow fire and boil 110min, leaching decoction；Relative density is condensed into as 1.08 3. secondary decoction is mixed Clear cream, then dry, grind and sterilize standby；
C, the method for 1. preparing Chinese medicine capsules according to tradition, after smalls sieving ground in B, with appropriate micro mist silicon Glue, microcrystalline cellulose and starch are well mixed, and are then prepared into capsule（Total length is 23.3mm after its capsule is sealed, and medicinal powder holds Measure 0.4~0.5g/ grains）, 2. then polish, sterilize, sealed packaging.
A kind of endo-medicine and preparation method for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer, it is characterised in that the clothes It is with method：By the capsule medicine prepared twice a day to take, once a dose in the morning, afternoon and evening, dosage 2.5g（5）/ Secondary, warm water delivery service, 30 days are a course for the treatment of, and after 3~4 courses for the treatment of of taking medicine, symptom gradually mitigates, and reduces postoperative serum first Shape gland globulin levels, so as to prevent cancerous swelling to recur and shift, patient clinical symptom is improved, improves minimal invasive treatment's matter Amount.
Each raw material Chinese medicine in prescription of the present invention has detailed in Chinese Pharmacopoeia, Chinese dictionary and its China's book on Chinese herbal medicine Record.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：
Japanese aralia bark, nature and flavor：It is pungent, flat, it is slightly poisonous, there is the effect of invigorating qi for tranquilization, strong smart nourshing kidney, expelling wind and activating blood flow, for treating god Demonstrate,proved through weak, rheumatic arthritis, diabetes and the weak, insufficiency of the kidney yang of deficiency of yang gas etc.；
Radix bupleuri, nature and flavor：It is bitter, be slightly cold, have and inducing diaphoresis in, soothing the liver, rising Yang the effect of, for treat cold, fever, fevers and chills alternate, The diseases such as distending pain in the chest and hypochondrium, irregular menstruation, sub-official prolapses, prolapse of the anus；
Beechey fig leaf, nature and flavor：It is sweet light, warm, it is nontoxic, there is tonifying middle-Jiao and Qi, invigorating the spleen for eliminating dampness, strengthen muscles and bones, subside a swelling, the work(of promoting blood circulation and detoxication Effect, for treating rheumatic arthritis, the middle deficiency of vital energy is weak, qi and blood is on the decline, four limbs are aching and limp, stiffness of muscle and joint, traumatic injury, Amenorrhea, milk It is obstructed；
Decumbent corydalis tuber, nature and flavor：Hardship, micro-pungent, temperature, there is the effect of promoting blood circulation and removing obstruction in channels, promoting qi circulation and relieving pain, for treating hemiplegia, falling and flutter Damage, rheumatic arthritis, sciatica；
Hairyvein agrimony, nature and flavor：It is bitter, puckery, flat, have astringing to arrest bleeding, preventing malaria, stop dysentery, removing toxic substances the effect of, for treat hemoptysis, haematemesis, Under metrostaxis, malaria, bloody flux, de-power internal lesion caused by overexertion, carbuncle sore tumefacting virus, pruritus vulvae band；
Rascal, nature and flavor：It is bitter, pungent, warm, there is the effect of soothing the liver relieving stagnant Qi, disperse accumulationsization is stagnant, for treating distending pain in the chest and hypochondrium, hernia, breast Core, acute mastitis, dyspeptic abdominalgia；
Curcuma zedoary, nature and flavor：It is acrid flavour, hardship, warm-natured, there is the effect of promoting the circulation of qi blood-breaking, Xiao Ji Zhi Tong, vim and vigour are pained, diet for treating Stagnant, abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhoea, abdominal mass knurl lump in the abdomen, traumatic injury；
Alocasia ordora, nature and flavor：It is micro-pungent, puckery, cold, it is poisonous, there is the effect of clearing heat and detoxicating, detumescence, for treating flu, pulmonary tuberculosis, intestines Worm, snake bite, sore swollen toxin are controlled in typhoid fever, external application；
Edible tulip, nature and flavor：It is sweet, micro-pungent, cool, there is the effect of clearing heat and detoxicating, reducing phlegm and resolving masses, for treating carbuncle swells serious case of furuncle, scrofula Subcutaneous nodule, scrofula, snake bite and insect sting；
Ligusticum wallichii, nature and flavor：It is acrid flavour, warm-natured, there is the effect of promoting blood circulation, promote breath and open depression, wind-expelling pain-stopping, for treating menstruation not Stagnant raw meat Tong, Disorder lump in the abdomen lump of tune, closed dysmenorrhea, the postpartum stasis of blood, pain in chest and hypochondrium, dizziness of having a headache, wind-cold-dampness arthralgia, traumatic injury, ulcer sore Ulcer；
Whorlleaf litse root, nature and flavor：It is bitter, pungent, warm, there is the effect of dispelling wind and removing obstruction in the meridians, activating blood circulation and reducing swelling, analgesic, for treating rheumatism joint Inflammation, pain in waist and lower extremities, quadriplegia, dysmenorrhoea, treating swelling and pain by traumatic injury；
Hedge glorybind root, nature and flavor：Sweet slight bitter, temperature, there is the effect of strengthening the essence gas, continuous muscles and bones, for treating erysipelas；
Rhizoma cyperi, nature and flavor are pungent, slight bitter, micro-sweet, flat, have the effect of promoting qi circulation and removing obstruction in the collateral, menstruction regulating and pain relieving, for treat stagnation of QI due to depression of the liver, chest, The side of body, abdominal distention, indigestion, chest gastral cavity ruffian, cold hernia stomachache, swollen breasts, irregular menstruation, closed dysmenorrhea；
Honey-fried licorice root, nature and flavor：It is sweet, flat, have invigorating middle warmer and replenishing QI, relieving spasm to stop pain, moisten the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription the effect of, For treating the thin face Huang of burnout deficiency of food, flesh, palpitation, stomachache loose stool, four limbs contraction, hysteria, cough and asthma, throat swell Bitterly, ulcerative carbuncle swelling and pain, infant fetal toxin and medicine, food poisoning；
Selfheal, nature and flavor are pungent, bitter, cold, have relieve inflammation or internal heat, improving eyesight, dissipating bind, detumescence the effect of, for treating red eye, swell pain, mesh pearl night Bitterly, dizziness of having a headache, scrofula, goiter and tumor, acute mastitis swelling and pain, Thyroid Gland Swell, scrofula, the proliferation of mammary gland, hypertension.
Medicine of the present invention is the principle based on the postoperative syndrome of qi stagnation and blood stasis of Chinese traditional treatment thyroid cancer, from according to thyroid cancer art The pathomechanism of syndrome of qi stagnation and blood stasis and pharmacological action are thought afterwards：It is provided by the present invention with regard to the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer Each raw material herbal medicine efficacy in medicine is played altogether, has good effect to above-mentioned disease.
Embodiment
A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of the postoperative syndrome of qi stagnation and blood stasis of above-mentioned thyroid cancer, is adopted The medicine effect prepared with the formula is good, quick, is a good Chinese prescription, is particularly suitable for Clinical practice.Tie below The embodiment for closing the present invention is described in further detail：
Embodiment 1：
A kind of endo-medicine for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer, it is characterised in that each component of the medicine and Its mass parts is than as follows：
Japanese aralia bark 360g, radix bupleuri 70g, beechey fig leaf 720g, decumbent corydalis tuber 115g, hairyvein agrimony 115g, rascal 80g, curcuma zedoary 95g, Alocasia ordora 200g, edible tulip 80g, Ligusticum wallichii 95g, whorlleaf litse root 115g, hedge glorybind root 118g, rhizoma cyperi 80g, honey-fried licorice root 95g, selfheal 115g, it is auxiliary Material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
Embodiment 2：
A kind of endo-medicine for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer, it is characterised in that each component of the medicine and Its mass parts is than as follows：
Japanese aralia bark 420g, radix bupleuri 80g, beechey fig leaf 850g, decumbent corydalis tuber 130g, hairyvein agrimony 130g, rascal 90g, curcuma zedoary 105g, Alocasia ordora 220g, edible tulip 90g, Ligusticum wallichii 105g, whorlleaf litse root 130g, hedge glorybind root 130g, rhizoma cyperi 90g, honey-fried licorice root 105g, selfheal 130g, Auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
Embodiment 3：
A kind of endo-medicine for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer, it is characterised in that each component of the medicine and Its mass parts is than as follows：
Japanese aralia bark 500g, radix bupleuri 90g, beechey fig leaf 1000g, decumbent corydalis tuber 150g, hairyvein agrimony 150g, rascal 100g, curcuma zedoary 120g, sea Taro 250g, edible tulip 100g, Ligusticum wallichii 120g, whorlleaf litse root 150g, hedge glorybind root 160g, rhizoma cyperi 100g, honey-fried licorice root 120g, selfheal 160g, auxiliary material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
Model case
Through the postoperative syndrome of qi stagnation and blood stasis patient of clinical conditions thyroid cancer totally 1190, the age is 710 of more than 38 years old, only It is less than 38 years old to have 480.Symptom gradually mitigates and prevents 750 of cancerous swelling recurrence and transfer in 1190 patients, effectively 321, invalid 119.Total effective rate is up to 90%.

Claims (3)

  1. A kind of 1. endo-medicine for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer, it is characterised in that each component of the medicine And its mass parts are than as follows：
    250~500g of japanese aralia bark, 30~90g of radix bupleuri, 500~1000g of beechey fig leaf, 60~150g of decumbent corydalis tuber, hairyvein agrimony 60~ 150g, 30~100g of rascal, 30~120g of curcuma zedoary, 150~250g of Alocasia ordora, 30~100g of edible tulip, 30~120g of Ligusticum wallichii, bruise Old 50~150g, 100~160g of hedge glorybind root, 60~100g of rhizoma cyperi, 30~120g of honey-fried licorice root, 90~160g of selfheal, auxiliary material：It is micro- Powder silica gel, microcrystalline cellulose and appropriate starch.
  2. 2. the endo-medicine of the treatment postoperative syndrome of qi stagnation and blood stasis of thyroid cancer according to claim 1, it is characterised in that described The each component and its mass parts of medicine are than as follows：
    280~420g of japanese aralia bark, 38~80g of radix bupleuri, 420~850g of beechey fig leaf, 70~130g of decumbent corydalis tuber, hairyvein agrimony 70~ 130g, 38~90g of rascal, 30~105g of curcuma zedoary, 180~220g of Alocasia ordora, 38~90g of edible tulip, 38~105g of Ligusticum wallichii, whorlleaf litse root 58~130g, 115~130g of hedge glorybind root, 70~90g of rhizoma cyperi, 38~105g of honey-fried licorice root, 100~130g of selfheal, auxiliary material：Micro mist Silica gel, microcrystalline cellulose and appropriate starch.
  3. 3. the endo-medicine of the postoperative syndrome of qi stagnation and blood stasis for the treatment of thyroid cancer according to claim 1 to 2, it is characterised in that The each component and its mass parts of the medicine are than as follows：
    Japanese aralia bark 360g, radix bupleuri 70g, beechey fig leaf 720g, decumbent corydalis tuber 115g, hairyvein agrimony 115g, rascal 80g, curcuma zedoary 95g, Alocasia ordora 200g, edible tulip 80g, Ligusticum wallichii 95g, whorlleaf litse root 115g, hedge glorybind root 118g, rhizoma cyperi 80g, honey-fried licorice root 95g, selfheal 115g, it is auxiliary Material：Superfine silica gel powder, microcrystalline cellulose and appropriate starch.
CN201710798367.6A 2017-09-07 2017-09-07 A kind of endo-medicine and preparation method for treating the postoperative syndrome of qi stagnation and blood stasis of thyroid cancer Withdrawn CN107469003A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105999063A (en) * 2016-06-08 2016-10-12 青岛云天生物技术有限公司 Medicinal preparation for treating qi stagnation and blood stasis syndrome after operation for thyroid cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105999063A (en) * 2016-06-08 2016-10-12 青岛云天生物技术有限公司 Medicinal preparation for treating qi stagnation and blood stasis syndrome after operation for thyroid cancer

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