CN105288334A - Gastric cancer treatment medicine for oral administration and preparation method of gastric cancer treatment medicine for oral administration - Google Patents

Gastric cancer treatment medicine for oral administration and preparation method of gastric cancer treatment medicine for oral administration Download PDF

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CN105288334A
CN105288334A CN201510693539.4A CN201510693539A CN105288334A CN 105288334 A CN105288334 A CN 105288334A CN 201510693539 A CN201510693539 A CN 201510693539A CN 105288334 A CN105288334 A CN 105288334A
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medicine
radix
gastric cancer
oral administration
cancer treatment
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孙素蓉
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Sichuan Juhao Biotechnology Co Ltd
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Sichuan Juhao Biotechnology Co Ltd
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Abstract

The invention belongs to the technical field of traditional Chinese medicines and aims to provide a gastric cancer treatment medicine for oral administration according to gastric cancer cognitive mechanisms of traditional Chinese medicine. The gastric cancer treatment medicine for oral administration is composed of 3-10g of radix notoginseng, 7-25g of codonopsis pilosula, 3-12g of pseudobulbus cremastrae seu pleiones, 9-31g of radix astragali, 5-15g of rhizoma atractylodis macrocephalae, 10-30g of raw semen coicis, 5-32g of piper longum, 3-10g of rhizoma pinelliae, 3-6g of radix euphorbiae lantu, 3-15g of pericarpium citri reticulatae and 7-16g of radix glycyrrhizae. The gastric cancer treatment medicine for oral administration has the advantages of high efficacy, quick action, short treatment period and few side effects, is capable of treating both symptoms and root causes and is especially suitable for clinical application.

Description

A kind of endo-medicine for the treatment of gastric cancer and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of endo-medicine for the treatment of gastric cancer, particularly for the field of the endo-medicine and preparation method thereof of patients with gastric cancer.
Background technology
According to the statistics made by the departments concerned, gastric cancer is one of cancer that in worldwide, sickness rate is the highest, and annual newly-increased 90-96 ten thousand patients with gastric cancer in the whole world, has more than 70 ten thousand people to die from gastric cancer simultaneously every year.The sickness rate of gastric cancer significantly raises along with the increase at age, and the peak age of morbidity was at 48 years old ~ 80 years old.Wherein: the sickness rate of male is 1.5 ~ 2.5 times of women, and mortality rate is only second to pulmonary carcinoma, occupies second.Meanwhile, the incidence gastric cancer rate of women and mortality rate have obvious ascendant trend.And China is the hotspot of gastric cancer, gastric cancer annual loading and mortality rate are all more than 2 times of world average level.Second National coroner's inquest result according to sanitation Ministry tissue shows, and the mortality rate of Chinese gastric cancer accounts for all because of number of cancer deaths's more than 24%, close to 1/4th.
Treatment at present to gastric cancer, doctor trained in Western medicine adopts operative treatment, radiotherapy or chemotherapy three one usually, or the method for together treating.Operative treatment: generally include radical surgery, palliative operation, detecting property is performed the operation.Namely take operation as means complete removal of lesions or cut-out focus, reach the method for curing or controlling cancer.Radiotherapy: be called for short radiotherapy, be utilize high-energy electromagnetic radiation line to act on life entity, biomolecular structure is changed, reach a kind of Therapeutic Method of destruction of cancer cells object.Radiation can Therapeutic cancer be because cancerous cell is responsive to lonizing radiation.The lonizing radiation applied clinically at present have x-ray to treat and r line treats two kinds.Chemotherapy: chemotherapy takes medicine intravascular to whole body, has impact to health all cells.This therapy is sometimes also referred to as " born of the same parents poison therapy ", because medicine used is all harmful, or even band toxicity, whether cells in vivo, no matter malignant cell, all can be damaged.No matter be adopt operative treatment, radiotherapy or adopt chemotherapy, all great financial burden and mental burden caused to the health of patient.
Summary of the invention
Along with the development of China's Chinese medicine, in Cure and control gastric cancer, people appreciate the advantage for the treatment of by Chinese herbs gastric cancer one disease gradually, and the advantage such as little, the painful little and low cost of side effect over the course for the treatment of, for the present situation of existing western medical treatment gastric cancer, the object of the invention is to be to provide a kind of endo-medicine for the treatment of gastric cancer, get well early and the problem of life-saving to solve patients with gastric cancer.This medicine be with common Chinese medicine for raw material, have that treatment cycle is short, instant effect, a feature such as evident in efficacy, and effectively can treat above-mentioned gastric cancer and extend patient's life-span.
For reaching the object of foregoing invention, the technical solution adopted in the present invention is: provide a kind of endo-medicine for the treatment of gastric cancer and preparation method thereof, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Notoginseng 3-10g;
Radix Codonopsis 7-25g;
Pseudobulbus Cremastrae Seu Pleiones 3-12g;
Radix Astragali 9-31g;
Rhizoma Atractylodis Macrocephalae 5-15g;
Raw Semen Coicis 10-30g;
Fructus Piperis Longi 5-32g;
Rhizoma Pinelliae 3-10g;
Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 3-6g;
Pericarpium Citri Reticulatae 3-15g;
Radix Glycyrrhizae 7-16g.
A kind of endo-medicine for the treatment of gastric cancer and preparation method thereof, is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Notoginseng 8g, Radix Codonopsis 23g, Pseudobulbus Cremastrae Seu Pleiones 10g, Radix Astragali 29g, Rhizoma Atractylodis Macrocephalae 13g, raw Semen Coicis 28g, Fructus Piperis Longi 30g, Rhizoma Pinelliae 8g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 5g, Pericarpium Citri Reticulatae 13g, Radix Glycyrrhizae 15g.
A kind of endo-medicine for the treatment of gastric cancer and preparation method thereof, is characterized in that, described method comprises the steps to be prepared from:
A, first above-mentioned raw materials Chinese medicine is picked decontamination and dust after, decoct a drug wrapped than being ground into coarse altogether according to mass parts;
B, traditionally prepare the method for Chinese medicine decoction, the medicine wrapped being put into cold boiled water soaks after 35 minutes, again soaked medicine is put into boiling machine, the cold boiled water injecting medicine 33mm decocts twice, first time decocts 35 minutes, after leaching medicinal liquid, re-injects tepor boiled water and carries out second time decoction 30 minutes, mixing is condensed into the herb liquid 1080 milliliters of 50%, for subsequent use after packed sealing.
A kind of endo-medicine for the treatment of gastric cancer and preparation method thereof, is characterized in that, described instructions of taking is: divided by the herb liquid prepared and take for two days, every day potion, the morning, noon and afternoon service once, dosage 180 milliliters/time, taking medicine before meal.To take medicine 25-350 agent, pain relief, food of receiving is good, complexion comparatively before have very large change, through check, cancerous cell without diffusing phenomenon, quality of life comparatively before have greatly improved.
Each raw material Chinese medicine in medicine of the present invention is all documented in detail in Chinese Pharmacopoeia, Chinese dictionary and Chinese book on Chinese herbal medicine.The present invention selects its modal Chinese medicine to be raw material, gives full play to the property of medicine of each component:
Radix Notoginseng, nature and flavor: sweet in the mouth, micro-hardship, warm in nature, have styptic powder blood, antiinflammatory, protect the liver, antitumor, analgesic therapy effect, be used for the treatment of and have a delicate constitution and all kinds of mass formed by blood stasis;
Radix Codonopsis, nature and flavor: property is flat, sweet in the mouth, micro-acid, there is effect of invigorating the spleen and replenishing QI, spleen invigorating lung benefiting, be used for the treatment of deficiency of the spleen and lung, the cough of cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency, interior-heat quench one's thirst;
Pseudobulbus Cremastrae Seu Pleiones, nature and flavor: sweet, micro-pungent, cool, have effect of heat-clearing and toxic substances removing, dissipating phlegm and resolving masses, antitumor, are used for the treatment of the diseases such as carbuncle furunculosis, scrofula sucutaneous nodule, tuberculous lymphadenitis, snake bite and insect sting;
The Radix Astragali, nature and flavor: sweet, warm, there is effect of invigorating QI to consolidate the body surface resistance, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation, granulation promoting, be used for the treatment of that the deficiency of vital energy is weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty burst, burst for a long time do not hold back, blood deficiency dull yellowish colored skin, interior-heat quench one's thirst, chronic nephritis proteinuria, diabetes;
The Rhizoma Atractylodis Macrocephalae, nature and flavor: bitter, sweet, warm, have invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, are used for the treatment of insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement;
Raw Semen Coicis, raw Semen Coicis has the effect of spleen invigorating, tonifying the lung, heat clearing away, dampness removing, and especially easily digests and assimilates, and is good dietetic therapy food, is applicable to weakness of the spleen and stomach person and eats.Raw Semen Coicis has spleen invigorating eliminating dampness by diuresis, effect of eliminating impediment antidiarrheal, is used for the treatment of edema, beriberi, dribbling urination, damp-warm diseases, have loose bowels leukorrhagia, rheumatic arthralgia etc.;
Fructus Piperis Longi, nature and flavor: pungent, hot, have effect of warming spleen and stomach for dispelling cold, therapeutic method to keep the adverse QI flowing downwards pain relieving, are used for the treatment of coldness and pain in the epigastrium, vomit, have loose bowels, migraine, and external treatment is had a toothache;
The Rhizoma Pinelliae, nature and flavor: acrid in the mouth, warm in nature, poisonous, have effect of drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, are used for the treatment of cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium headache dizzy, uneasy sleeping at night, gall subcutaneous nodule, swollen ulcer drug;
The Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae), nature and flavor: toil, flat, poisonous, having relieves oedema or abdominal distension through diuresis or purgation eliminates the phlegm, effect of removing mass parasite killing, is used for the treatment of the diseases such as tuberculosis, scabies, hemorrhoid complicated by anal fistula such as edema abdominal distention, expectorant, food, malnutrition due to parasitic infestation, trusted subordinate's pain, chronic tracheitis, cough, asthma, lymph node, skin, bone, epididymis;
Pericarpium Citri Reticulatae, nature and flavor: acrid in the mouth, hardship, warm in nature, there is regulating the flow of Qi and the middle Jiao, drying dampness to eliminate phlegm, effect of diuretic relieving constipation, is used for the treatment of incoordination between the spleen and stomach, abdominal distention, anorexia, vomiting hiccup, accumulation of phlegm-damp in the lung, cough with copious phlegm, chest and diaphragm full vexed, the vertigo, edema, dysuria, constipation, acute mastitis scabies, middle fish Eriocheir sinensis poison, alcoholism etc.;
Radix Glycyrrhizae, nature and flavor: sweet, flat, there is the effect with middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription, be used for the treatment of weakness of the spleen and stomach, lack of appetite, stomachache loose stool, overstrain heating, consumptive lung disease cough, cardiopalmus, infantile convulsion, raw with, control laryngopharynx swelling and pain, peptic ulcer, ulcer sores, solution poison of drug and alimentary toxicosis.
Medicine of the present invention is the treatment principle debating disease based on Chinese medicine, think from pharmacological action and mechanism of action: with regard to gastric cancer one disease, each raw material herbal medicine efficacy in endo-medicine provided by the present invention is played altogether, good therapeutical effect is had to gastric cancer, and to because of long-term chemicotherapy, thin and weak health has good conditioning effect.
Detailed description of the invention
The present invention is exactly treatment for above-mentioned gastric cancer and a kind of Chinese medicine formula proposed, and the medicine effect adopting this formula to prepare is good, and instant effect, treatment cycle are short, toxic and side effects is little, is the gastric cancer prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Be described in further detail below in conjunction with the specific embodiment of the present invention:
Embodiment 1:
A kind of endo-medicine for the treatment of gastric cancer and preparation method thereof, each component of described medicine and mass parts thereof are than as follows:
Radix Notoginseng 8g, Radix Codonopsis 23g, Pseudobulbus Cremastrae Seu Pleiones 10g, Radix Astragali 29g, Rhizoma Atractylodis Macrocephalae 13g, raw Semen Coicis 28g, Fructus Piperis Longi 30g, Rhizoma Pinelliae 8g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 5g, Pericarpium Citri Reticulatae 13g, Radix Glycyrrhizae 15g.
Embodiment 2:
A kind of endo-medicine for the treatment of gastric cancer and preparation method thereof, each component of described medicine and mass parts thereof are than as follows:
Radix Notoginseng 10g, Radix Codonopsis 25g, Pseudobulbus Cremastrae Seu Pleiones 12g, Radix Astragali 31g, Rhizoma Atractylodis Macrocephalae 15g, raw Semen Coicis 30g, Fructus Piperis Longi 2g, Rhizoma Pinelliae 10g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 6g, Pericarpium Citri Reticulatae 15g, Radix Glycyrrhizae 16g.
Embodiment 3:
A kind of endo-medicine for the treatment of gastric cancer and preparation method thereof, each component of described medicine and mass parts thereof are than as follows:
Radix Notoginseng 8g, Radix Codonopsis 23g, Pseudobulbus Cremastrae Seu Pleiones 10g, Radix Astragali 29g, Rhizoma Atractylodis Macrocephalae 13g, raw Semen Coicis 28g, Fructus Piperis Longi 30g, Rhizoma Pinelliae 8g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 5g, Pericarpium Citri Reticulatae 13g, Radix Glycyrrhizae 15g.
Model case:
Through clinical conditions patients with gastric cancer totally 30 example, male 20 example, women 10 example, the age be more than 50 years old 20 example, only have 10 example be the right side of fifty.17 examples of fully recovering in 30 routine patients, effective 5 examples, effective 5 examples, total effective rate reaches 90%.After treatment, the gastric cancer of patient has improvement in various degree and recovery from illness.

Claims (3)

1. can treat an endo-medicine for gastric cancer, it is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Notoginseng 3-10g;
Radix Codonopsis 7-25g;
Pseudobulbus Cremastrae Seu Pleiones 3-12g;
Radix Astragali 9-31g;
Rhizoma Atractylodis Macrocephalae 5-15g;
Raw Semen Coicis 10-30g;
Fructus Piperis Longi 5-32g;
Rhizoma Pinelliae 3-10g;
Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 3-6g;
Pericarpium Citri Reticulatae 3-15g;
Radix Glycyrrhizae 7-16g.
2. endo-medicine for the treatment of gastric cancer according to claim 1, is characterized in that, each component of described medicine and mass parts thereof are than as follows:
Radix Notoginseng 8g, Radix Codonopsis 23g, Pseudobulbus Cremastrae Seu Pleiones 10g, Radix Astragali 29g, Rhizoma Atractylodis Macrocephalae 13g, raw Semen Coicis 28g, Fructus Piperis Longi 30g, Rhizoma Pinelliae 8g, Radix Euphorbiae Fischerianae (Radix Euphorbiae Ebracteolatae) 5g, Pericarpium Citri Reticulatae 13g, Radix Glycyrrhizae 15g.
3. a kind of endo-medicine for the treatment of gastric cancer described in a claim 1 to 2 and preparation method thereof, is characterized in that, described method comprises the steps:
A, first above-mentioned raw materials Chinese medicine is picked decontamination and dust after, decoct a drug wrapped than being ground into coarse altogether according to mass parts;
B, traditionally prepare the method for Chinese medicine decoction, the medicine wrapped being put into cold boiled water soaks after 35 minutes, again soaked medicine is put into boiling machine, the cold boiled water injecting medicine 33mm decocts twice, first time decocts 35 minutes, after leaching medicinal liquid, re-injects tepor boiled water and carries out second time decoction 30 minutes, mixing is condensed into the herb liquid 1080 milliliters of 50%, for subsequent use after packed sealing.
CN201510693539.4A 2015-10-24 2015-10-24 Gastric cancer treatment medicine for oral administration and preparation method of gastric cancer treatment medicine for oral administration Withdrawn CN105288334A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108938960A (en) * 2018-07-17 2018-12-07 宁夏医科大学 A kind of drug and preparation method thereof for treating gastric cancer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104721793A (en) * 2015-04-04 2015-06-24 四川双鑫生物科技有限公司 Oral medicament for treating intercourse convulsion and preparation method of oral medicament

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104721793A (en) * 2015-04-04 2015-06-24 四川双鑫生物科技有限公司 Oral medicament for treating intercourse convulsion and preparation method of oral medicament

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
屠佑堂等: "《中医实用诊疗大全 下》", 31 March 2013, 湖北科学技术出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108938960A (en) * 2018-07-17 2018-12-07 宁夏医科大学 A kind of drug and preparation method thereof for treating gastric cancer

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