CN107496314A - A kind of cosmetic composition - Google Patents
A kind of cosmetic composition Download PDFInfo
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- CN107496314A CN107496314A CN201610420023.7A CN201610420023A CN107496314A CN 107496314 A CN107496314 A CN 107496314A CN 201610420023 A CN201610420023 A CN 201610420023A CN 107496314 A CN107496314 A CN 107496314A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to cosmetic field, and in particular to a kind of cosmetic composition.Said composition contains Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract, Sodium Hyaluronate.It is characteristic of the invention that the cosmetic composition is using the composition of a variety of natural origins as main active component；Can timely moisturizing, the long-acting moisturizing of and can, make skin present water profit state；Cellular respiration can be promoted simultaneously, lift cell consumption rate, promote cell metabolism, reduce oxidative stress；And free radical and active oxygen can be effectively removed, impaired skin is repaired, reaches the effect of protecting skin.Each component reasonable combination, synergy is safe and stable, can be used for moisturizing, in the cosmetics that energy is provided for skin.
Description
Technical field
The present invention relates to cosmetic field, and in particular to a kind of cosmetic composition.
Background technology
With advancing age, the turnover rate of human keratinous layer becomes slower and slower, while the lipid synthesis of horn cell
Ability declines, or cell division, growth and differentiation efficiency step-down in epidermis.Because skin lacks moisturizing factor and lipid, angle
Matter layer barrier function declines increasingly.When cuticula moisture is less than 10%, skin, which will seem, to be dried, follows the string, rising
Wrinkle, and then accelerate skin aging.On the other hand, improperly life style it is for example excessive wash one's face or have a bath and bad environment because
Element can also make cuticula such as the air or pollutant and intrinsic disease such as allergy (atopy) or senile skin disease dried
Lose the function of its script.Skin is encroached on by sweltering heat, cold, wind, cleaning agent and ultraviolet radiation etc., and top layer can become more
Add drying.Water is the important composition composition of skin, and the high skin of water content, epidermal cell metabolism is normal, and epidermis energy fills
Foot, show tender, plentiful, glossy and soft outward appearance.For example infant's skin is seemed delicate light due to its water content higher position
Pool, and old application on human skin is because water content is relatively low, seem and dry and flat, the easy furfur that withers, wrinkle even occurs.Cause
How this, keep the moisture of skin, and it is particularly significant in cosmetics research and development to reduce moisture loss.
In addition, with age, the secretion of the hormone of the various regulation metabolism of human body skin itself is reduced, and is immunized thin
The function and activity decrease of born of the same parents, this reduces the synthesis of the immune protein and structural proteins that cause to form live body.Form skin
Collagen, elastin laminin, hyaluronic acid and the content of glycoprotein and arrangement (arrangement) change or reduced, and due to
Free radical and active oxygen and oxidative stress occurs.Reach the amount of earth surface ultraviolet increases due to the destruction of ozone layer, and
It is on the rise with environmental pollution, free radical and active oxygen increase.Thinning of skin, wrinkle increase, skin elasticity declines, the colour of skin
Become obscure, various skin problems frequently occur.Therefore, in cosmetics design, in addition to moisturizing, it is also contemplated that removing certainly
By base and active oxygen, and how to promote cellular respiration.
At present, in the market has that the cosmetics of moisture-keeping efficacy are very more, and is not solely restricted to top layer moisturizing, vertical
Body, deep layer, maintenance, long-acting aspect propose " 4D moisturizings ", " 6D moisturizings " concept, and develop more efficient natural moisturizings
Agent.Although these measures can timely moisturizing, strengthen the water lock of skin, water storage, water delivery barrier function, be the failure to fundamentally change
Become the dry sensation of skin.Secondly, also there is the product for declaring " multi-efficiency " in the market, and freedom can be removed while moisturizing
Base, there is anti-oxidation efficacy, but actual research effect shows that they only possess the effect of simple superposition mostly, not
Have to multiple skin problems and be obviously improved effect.
The content of the invention
In order to solve the above-mentioned technical problem, first purpose of the invention is to provide a kind of skin care compositions, said composition
Can in timely moisturizing, can timely moisturizing, the long-acting moisturizing of and can, make skin present water profit state；Cell can be promoted to exhale simultaneously
Inhale, lift cell consumption rate, promote cell metabolism, reduce oxidative stress；And free radical and active oxygen can be effectively removed,
Impaired skin is repaired, reaches the effect of protecting skin.Second object of the present invention is to provide a kind of using above-mentioned skin care group
The cosmetics of compound.
In order to realize first above-mentioned purpose, present invention employs following technical scheme：
A kind of cosmetic composition, as mass fraction said composition include following component：
0.01 ~ 20 part of Margarita extract
0.01 ~ 10 part of saccharomycete lysis thing extract
0.01 ~ 20 part of Fructus psidii guajavae immaturus extract
0.001 ~ 1 part of Sodium Hyaluronate.
Preferably, said composition includes following component as mass fraction：
0. 1 ~ 10 parts of Margarita extract
0.05 ~ 5 part of saccharomycete lysis thing extract
0.1 ~ 10 part of Fructus psidii guajavae immaturus extract
0.01 ~ 0.2 part of Sodium Hyaluronate.
As further preferably, said composition includes following component as mass fraction：
0. 5 ~ 5 parts of Margarita extract
0.1 ~ 5 part of saccharomycete lysis thing extract
0.5 ~ 5 part of Fructus psidii guajavae immaturus extract
0.02 ~ 0.15 part of Sodium Hyaluronate.
Margarita extract in the cosmetic composition be on the basis of super-fine pearl powder powder, by biological enzymolysis technique,
Reversed phase high-pressure liquid phase separation techniques, obtain and possess the polypeptide of active function, its content of peptides between 1.0-20.0mg/ml, Gu
Content is between 2.0-20.0%.Moisturizing water lock not only is played in skin surface, more from basalis maintenance cellular environment, promotes glue
The secretion of the water lock composition such as former albumen, play deep layer multiple-effect moisture-keeping function.
Saccharomycete lysis thing extract of the present invention is yeast cells in controlled ambient pressure（As necessarily
Dose ultraviolet line irradiates）Caused metabolite under condition of culture, got through breaking-wall cell extraction, also known as yeast living cells spreads out
Biology（Live Cell Yeast Derivatives, abbreviation LYCD）.This typical eukaryotic of yeast is pressed when by the external world
The reaction that power is made when stimulating has many similarities with mankind fibroblast, and this is the active ingredient in cosmetics
Using providing theoretical foundation.
Yeast lysis thing extract is by the material composition of the low relative molecular masses such as amino acid, glycopeptide, nucleotides, and this is carried
Thing active matter content is taken between 25%-40%.The extract can increase new in Skin Cell as a kind of peculiar NMF
The absorption of raw albumen confrontation moisture, promote utilization of the skin to oxygen, so that skin is plentiful.The extract also has promotion transparent
Matter acid synthesis, promotes the synthesis of elastin laminin and collagen, suppresses free radical, increase cell aerobic respiration, releive, promote wound
Healing and other effects.Human test shows that the extract can strengthen skin moisture-keeping, strengthens skin tightness, improves skin UV damages
Wound, energy is refilled for skin, allow skin to keep fit state.
Guava in the cosmetic composition is tropical fruit tree, is evergreen dungarunga or shrub, be commonly called as pulling out guava,
That is pulled out.Because it is from foreign countries, therefore named is guava, is one of subtropical zone famous and high-quality fruit kind.Fruit have treatment diabetes and
Hypoglycemic drug effect, blade can also control diarrhoea.Fruit can also be processed into fruit juice, inspissated juice, fruit powder, jam, concentration in addition to eating raw
Slurry, jelly etc..Alphalin, B, E, and two kinds strong effective polyphenoils --- Punica granatum L. polyphenol and anthocyanidin are rich in guava,
Free radical can be effectively neutralized, is enhanced metabolism, effectively helps skin discharge " toxin ".
Sodium Hyaluronate in the cosmetic composition, is a kind of macromolecule NMF of natural origin, and its molecular weight divides
Cloth is in 1.0*105Da and 3.0*106Between Da, purity is more than 90%.Layer protecting film can be formed in skin surface, protect flesh
Skin, strengthen skin barrier function.
In order to realize second above-mentioned purpose, present invention employs following technical scheme：
A kind of cosmetics, this is used for cosmetic in moisturizing, moisturizing, repairs and/or energizes, the cosmetics include a kind of above-mentioned cosmetic
Product composition.
Preferably, the cosmetics are face cream, facial treatment milk, skin-care gel, facial treatment essence liquid or surfactant.
The present invention not only plays moisturizing water lock as a result of above-mentioned technical scheme, Margarita extract in skin surface,
More from basalis maintenance cellular environment, promote the secretion of the water lock compositions such as collagen, play deep layer multiple-effect moisture-keeping function.It is and saturating
Bright matter acid sodium, layer protecting film mainly is formed in skin surface, strengthen skin barrier function, pin moisture.Yeast lysis thing carries
Take thing that skin can be promoted to synthesize hyaluronic acid, elastin laminin and collagen, absorption of the increase skin to moisture, while can press down
Free radical processed, increase cell aerobic respiration, lift cell consumption rate, promote cell metabolism, reduce oxidative stress.Can be effective
Free radical is neutralized, is enhanced metabolism.The compounding of several active components of the present invention, is not merely moisturizing or benefit in traditional sense
Water effect, but while moisturizing moisturizing, maintenance is damaged skin, understands free radical in skin, provides energy for skin, makes flesh
The restorative water profit state of skin.
Brief description of the drawings
Fig. 1 be moisturizing emulsion use before, the keratoderma change of moisture content rate of 4 hours after 1 hour and use after use
Figure.
Fig. 2 is volunteer's wrinkle depth analysis chart.
Embodiment
Cosmetic composition provided by the invention is carried with Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus
It is main component to take thing, Sodium Hyaluronate, be aided with cosmetics often with matrix components emulsifying agent, emollient, NMF, thickener,
Preservative, chelating agent, essence and water are made.A part of specific embodiment is set forth below, and the present invention will be described, but not
Limit present disclosure.
Embodiment 1
Surfactant：
Form above-mentioned composition surfactant component and its relative content be：
The preparation method of above-mentioned surfactant, comprises the following steps：Water, glycerine, Sodium Hyaluronate and xanthans are added into reaction pot
In, stirring is opened, 75 ~ 80 DEG C is heated to, is uniformly dispersed；Cooling circulating water is opened, stirring cools, when temperature is down to 40 ~ 45 DEG C,
Margarita extract, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract and preservative are added in reaction pot, stirring and dissolving is complete
Entirely；Continue stirring and be cooled to material temperature less than 38 DEG C, stop stirring, terminate.
Embodiment 2
Facial treatment essence liquid：
The component and its relative content for forming above-mentioned facial treatment essence liquid be：
The preparation method of above-mentioned facial treatment essence liquid, comprises the following steps：By water, 1,3- propane diols, acryloyldimethyl taurine
Ammonium/VP copolymers, xanthans and Sodium Hyaluronate are added in reaction pot, are opened stirring, are heated to 75 ~ 80 DEG C, are uniformly dispersed；
Open cooling circulating water, stirring cooling, when temperature is down to 40 ~ 45 DEG C, add Margarita extract, saccharomycete lysis thing extract,
Fructus psidii guajavae immaturus extract, essence and preservative are added in reaction pot, and homogeneous 1 minute, stirring and dissolving is complete；Continue stirring to be cooled to
Material temperature is less than 38 DEG C, stops stirring, terminates.
Embodiment 3
Skin-care gel：
The component and its relative content for forming above-mentioned skin-care gel be：
The preparation method of above-mentioned skin-care gel, comprises the following steps：Water, glycerine, xanthans, allantoin and Sodium Hyaluronate are added
Enter in aqueous phase pot, open stirring, be heated to 75 ~ 80 DEG C, be uniformly dispersed, as A phases；By caprylic/capric triglyceride, poly- diformazan
Radical siloxane, carbonic acid dibutyl ester and hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers are added in oil phase pot, heating
To 75 ~ 80 DEG C, it is dispersed with stirring uniformly, as B phases；A phases are pumped into homogeneous reaction pot with B phases, high speed homogenization 5 minutes, opened cold
But recirculated water, stirring cooling, when temperature is down to 40 ~ 45 DEG C, Margarita extract, saccharomycete lysis thing extract, kind stone are added
Pomegranate berry extract, essence and preservative are added in reaction pot, homogeneous 1 minute；Continue stirring and be cooled to material temperature less than 38 DEG C, stop
Stirring, terminate.
Embodiment 4
Facial treatment milk：
The component and its relative content for forming above-mentioned facial treatment milk be：
The preparation method of above-mentioned facial treatment milk, comprises the following steps：By water, 1,3 propane diols, glycerine, Sodium Hyaluronate, acryloyl
Dimethyltaurine ammonium/VP copolymers, Phosphoric acid monohexadecyl ester potassium add aqueous phase pot, and heating stirring is dispersed with stirring to 75 ~ 80 DEG C
Uniformly, as A phases；By cetostearyl alcohol, different hexadecanol, shea butter, dimethyl silicone polymer, caprylic/capric triglyceride,
Dormant oils is added in oil cauldron, and heating stirring is stirred to complete and melted, as B phases to 75 ~ 80 DEG C；A phases are pumped into homogeneous reaction pot
In, stirring is opened, B phases is pumped into, homogeneous 5 minutes, opens cooling circulating water, stirring cooling；Extracted to pearl is added at 45 ~ 50 DEG C
Thing, saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract, essence and preservative, stirring and dissolving are complete；Continue stirring to material temperature
After 38 DEG C, stop stirring, terminate.
Embodiment 5
Face cream：
The component and its relative content for forming above-mentioned face cream be：
The preparation method of above-mentioned face cream, comprises the following steps：By glycerine, 1,3- propane diols, glycerine polyacrylate, hyalomitome
Sour sodium and water add aqueous phase pot, and heating stirring is uniformly dispersed to 75 ~ 80 DEG C, as A phases；By methyl sesquistearate,
It is PEG-20 methyls sesquistearate, cetostearyl alcohol, virgin oil, shea butter, dimethyl silicone polymer, pungent
Acid/Triglyceride DDD, cetostearyl alcohol ethylhexoate, tocopherol are added in oil cauldron, and heating stirring is to 75~80 DEG C, stirring
Melted to complete, as B phases；A phases are pumped into homogeneous reaction pot, open stirring, B phases is pumped into, homogeneous 5 minutes, adds
SIMULGEL EG, high speed homogenization 3 minutes, open cooling circulating water, stirring cooling；To at 45 ~ 50 DEG C add Margarita extract,
Saccharomycete lysis thing extract, Fructus psidii guajavae immaturus extract, essence and preservative, stir；Continue stirring to material temperature to be not higher than
After 38 DEG C, stop stirring, terminate.
The moisture-keeping efficacy of embodiment 6 is evaluated
The facial treatment milk provided in this experimental selection embodiment 4 carries out clinical trial.
The experiment includes 22 volunteers, and the age is in 21-45 one full year of life.Tested material and data are used according to regulations during experiment
It is complete.It is unified to clean both hands inner forearm before experiment, carry out measurement markers.Product smear zone and blank district random distribution
Region is demarcated in left and right arm, it is ensured that all product and white space positions statistically reach balance.First measure each region
Initial value, then test sample is pressed into ormal weight single application.In setting time point product is carried out using moisture of skin tester
Region and the measurement of control zone, each region parallel determination 5 times, record of averaging.
According to formula keratoderma change of moisture content rate=[（Th-T0）- (Th blank-T0 blank)]/T0, calculate moisturizing
Before emulsion use, the keratoderma change of moisture content rate of 4 hours after 1 hour and use after use, see Fig. 1.As a result show, protect
Skin emulsion keratoderma water content has after 1h to improve a lot, and can preferably be tieed up within 4 hours after use
Hold.
The instant anti-wrinkle effect assessment of embodiment 7
The facial treatment milk provided in this experimental selection embodiment 4 carries out clinical trial.
The experiment includes 5 volunteers, and the age is in 25-45 one full year of life.Appropriate emulsion is taken to be applied at eye microgroove.Use finger
Finger pulp is flicked eye and all absorbed to sample.With imported from America VISIA-CR professional skin image analysis systems to eye part skin
Wrinkle index using it is preceding and using 30 minutes after analyzed.After having used emulsion 30 minutes, wrinkle depth ratio is using preceding subtracting
Lack 10%, seen a certain position volunteer wrinkle depth analysis charts of Fig. 2.Ridge part represents skin bulge part, ridge portion in Fig. 2
It is point more, represent that wrinkle of skin is fewer.
Claims (10)
1. a kind of cosmetic composition, it is characterised in that said composition includes following component as mass fraction：
0.01 ~ 20 part of Margarita extract
0.01 ~ 10 part of saccharomycete lysis thing extract
0.01 ~ 20 part of Fructus psidii guajavae immaturus extract
0.001 ~ 1 part of Sodium Hyaluronate.
2. a kind of cosmetic composition according to claim 1, it is characterised in that said composition includes as mass fraction
Following component：
0. 1 ~ 10 parts of Margarita extract
0.05 ~ 5 part of saccharomycete lysis thing extract
0.1 ~ 10 part of Fructus psidii guajavae immaturus extract
0.01 ~ 0.2 part of Sodium Hyaluronate.
3. a kind of cosmetic composition according to claim 1, it is characterised in that said composition includes as mass fraction
Following component：
0. 5 ~ 5 parts of Margarita extract
0.1 ~ 5 part of saccharomycete lysis thing extract
0.5 ~ 5 part of Fructus psidii guajavae immaturus extract
0.02 ~ 0.15 part of Sodium Hyaluronate.
4. according to a kind of cosmetic composition described in claim 1 ~ 3 any one claim, it is characterised in that pearl carries
It is pearl powder through digesting the mixtures of obtained a variety of peptides and amino acid to take thing.
5. a kind of cosmetic composition according to claim 4, it is characterised in that content of peptides exists in Margarita extract
1.0-20.0mg/ml between, solid content is between 2.0-20.0%.
6. according to a kind of cosmetic composition described in claim 1 ~ 3 any one claim, it is characterised in that female bacterium is molten
Born of the same parents' thing extract, it is yeast cells caused metabolite under controlled ambient pressure condition of culture, is carried through breaking-wall cell
Obtain and, by including amino acid, glycopeptide, the material composition of nucleotides and other low relative molecular masses, the extract do not wave
Stimulating food content is between 25%-40%.
7. according to a kind of cosmetic composition described in claim 1 ~ 3 any one claim, it is characterised in that guava
Berry extract solid content is in 1%-2%.
8. according to a kind of cosmetic composition described in claim 1 ~ 3 any one claim, it is characterised in that hyalomitome
Sour sodium molecule amount is distributed in 1.0*105Da and 3.0*106Between Da, purity is more than 90%.
9. a kind of cosmetics, this is used for cosmetic in moisturizing, moisturizing, repairs and/or energizes, it is characterised in that the cosmetics include root
According to a kind of cosmetic composition described in claim 1 ~ 3 any one claim.
10. a kind of cosmetic composition according to claim 9, it is characterised in that the cosmetics are face cream, skin care milk
Liquid, skin-care gel, facial treatment essence liquid or surfactant.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610420023.7A CN107496314A (en) | 2016-06-13 | 2016-06-13 | A kind of cosmetic composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610420023.7A CN107496314A (en) | 2016-06-13 | 2016-06-13 | A kind of cosmetic composition |
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| Publication Number | Publication Date |
|---|---|
| CN107496314A true CN107496314A (en) | 2017-12-22 |
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ID=60679161
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610420023.7A Pending CN107496314A (en) | 2016-06-13 | 2016-06-13 | A kind of cosmetic composition |
Country Status (1)
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105078873A (en) * | 2014-05-16 | 2015-11-25 | 天津强微特生物科技有限公司 | Biological skin protecting composition with tightening and whitening effects |
| CN105434312A (en) * | 2015-12-30 | 2016-03-30 | 天津嘉氏堂科技有限公司 | Psidium guajava moisturizing toner |
-
2016
- 2016-06-13 CN CN201610420023.7A patent/CN107496314A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105078873A (en) * | 2014-05-16 | 2015-11-25 | 天津强微特生物科技有限公司 | Biological skin protecting composition with tightening and whitening effects |
| CN105434312A (en) * | 2015-12-30 | 2016-03-30 | 天津嘉氏堂科技有限公司 | Psidium guajava moisturizing toner |
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