CN107468901A - 一种可有效治疗颈椎病的内服药物及其制备方法 - Google Patents
一种可有效治疗颈椎病的内服药物及其制备方法 Download PDFInfo
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Abstract
本发明属于中药制剂领域,目的是根据中医治疗颈椎病的认识机理而提供一种可有效治疗颈椎病的内服药物,所述药物的各个组分及其质量份比如下:连翘150~300g、熟地黄120~380g、川芎50~120g、肉苁蓉100~160g、薄荷50~120g、茯苓250~550g、厚朴30~120g、鹿衔草150~350g、伸筋草90~160g、骨碎补100~250g、蒲黄50~120g、木香20~80g、枸杞50~160g、黄精150~260g、独一味30~80g、鸡血藤(烤)100~160g、淫羊藿50~150g、红花50~120g、蒲公英100~350g、莱菔子(炒)50~120g、桔梗50~120g、甘草30~150g、乳香30~120g,本发明提供的药物是一个很好的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种可有效治疗颈椎病的内服药物,特别是供颈椎病患者使用的内服药物及其制备方法的领域。
背景技术
据有关资料显示:颈椎病又称颈椎综合征,是颈椎骨关节炎、增生性颈椎炎、颈神经根综合征、颈椎间盘脱出症的总称,是一种以退行性病理改变为基础的疾患。主要由于颈椎长期劳损、骨质增生,或椎间盘脱出、韧带增厚,致使颈椎脊髓、神经根或椎动脉受压,出现一系列功能障碍的临床综合征。表现为椎节失稳、松动;髓核突出或脱出;骨刺形成;韧带肥厚和继发的椎管狭窄等,刺激或压迫了邻近的神经根、脊髓、椎动脉及颈部交感神经等组织,引起一系列症状和体征。颈椎病可分为:颈型颈椎病、神经根型颈椎病、脊髓型颈椎病、椎动脉型颈椎病、交感神经型颈椎病、食管压迫型颈椎病。
那么,就如何找到一种可效治疗颈椎病的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗颈椎病上,人们逐渐意识到了中医治疗颈椎病的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗颈椎病的现状,本发明的目的是在于提供一种可有效治疗颈椎病的内服药物,以解决颈椎病患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述颈椎病。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种可有效治疗颈椎病的内服药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
连翘150~300g、熟地黄120~380g、川芎50~120g、肉苁蓉100~160g、薄荷50~120g、茯苓250~550g、厚朴30~120g、鹿衔草150~350g、伸筋草90~160g、骨碎补100~250g、蒲黄50~120g、木香20~80g、枸杞50~160g、黄精150~260g、独一味30~80g、鸡血藤(烤)100~160g、淫羊藿50~150g、红花50~120g、蒲公英100~350g、莱菔子(炒)50~120g、桔梗50~120g、甘草30~150g、乳香30~120g。
一种可有效治疗颈椎病的内服药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
连翘180~260g、熟地黄135~350g、川芎58~105g、肉苁蓉115~130g、薄荷58~105g、茯苓280~480g、厚朴38~105g、鹿衔草180~320g、伸筋草100~130g、骨碎补115~220g、蒲黄58~105g、木香26~70g、枸杞58~130g、黄精180~230g、独一味38~70g、鸡血藤(烤)115~130g、淫羊藿58~130g、红花58~105g、蒲公英115~300g、莱菔子(炒)58~105g、桔梗58~105g、甘草38~130g、乳香38~105g。
一种可有效治疗颈椎病的内服药物及其制备方法,其特征在于,所述药物的各个组分及其质量份比如下所示:
连翘230g、熟地黄320g、川芎95g、肉苁蓉118g、薄荷95g、茯苓420g、厚朴95g、鹿衔草280g、伸筋草115g、骨碎补200g、蒲黄95g、木香60g、枸杞115g、黄精200g、独一味60g、鸡血藤(烤)118g、淫羊藿115g、红花95g、蒲公英260g、莱菔子(炒)95g、桔梗95g、甘草115g、乳香95g。
A、将上述原料中药拣去杂质和粉尘后,按照质量份比分别粉碎成粗粒状包煎;
B、①将包好的原料中药放入冷开水中浸泡50min,然后再将浸泡好的药物和浸泡药物的澄清液一并放入砂锅内,加入原料中药重量7~8 倍的冷开水进行第一次武火煎煮,待煎煮到18min时,转文火熬制100min,滤取药液;②药渣中再次加入原料中药重量6~7 倍的冷开水进行第二次武火煎煮,待煎煮到15min时,转文火熬制90min,滤取药液;③将两次药液混合浓缩成相对密度为1.08 的清膏,然后干燥、研末和消毒后待用;
C、①按照传统制备中药胶囊剂的方法,将研磨好的细末过筛后,放入药器中混合均匀,然后制备成胶囊剂(其胶囊锁合后总长度为23.3mm,药粉容量0.4~0.5g/粒),②进而抛光、消毒,分装密封即可。
一种可有效治疗颈椎病的内服药物及其制备方法,其特征在于,所述服用方法为:将制备好的胶囊剂药物以每日二次服用,早晚各服一次,给药量2.5g(5粒)/次,温开水送服。30天为一个疗程,服药1~3个疗程,症状逐渐消失,病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
连翘,性味:苦、凉,具有清热、解毒、散结、消肿之功效,用于治疗温热、丹毒、斑疹、痈疡肿毒、瘰疬、小便淋闭;
熟地黄,性味:甘、微温,具有滋阴补血、益精填髓之功效,用于治疗肝肾阴虚、腰膝酸软、骨蒸潮热、盗汗遗精、内热消渴、血虚萎黄、心悸怔忡、月经不调、崩漏下血、眩晕、耳鸣、须发早白;
川芎,性味:辛、温,具有行气开郁、法风燥湿、活血止痛之功效,用于治疗风冷头痛旋晕、胁痛腹疼、寒痹筋挛、经闭、难产、产后瘀阻块痛、痈疽疮疡、月经不调、瘕腹痛、胸胁刺痛、跌扑肿痛、风湿痹痛;
肉苁蓉,性味:味甘、咸、性温,具有补肾阳、益精血、润肠道之功效,用于治疗肾阳虚衰、精血不足之阳痿、遗精、白浊、尿频余沥、腰痛脚弱、耳鸣目花、月经衍期、宫寒不孕、肠燥便秘;
薄荷,性味:味辛、性凉,具有散风热、清头目、利咽喉、透疹、解郁之功效,用于治疗风热表证、头痛目赤、咽喉肿痛、麻疹不透、陷疹瘙痒、肝郁胁痛;
茯苓,性味:甘淡、平,具有解毒、除湿、利关节之功效,用于治疗梅毒、淋浊、筋骨挛痛、脚气、疔疮、痈肿、瘰疬等症;
厚朴,性味:苦、辛、性温,具有行气消积、燥湿除满、降逆平喘之功效,用于治疗食积气滞、腹胀便秘、湿阻中焦、脘痞吐泻、痰壅气逆、胸满喘咳;
鹿衔草,性味:甘、苦、性温,具有补肾强骨、祛风除湿、止咳、止血之功效,用于治疗肾虚腰痛、风湿痹痛、筋骨痿软、新久咳嗽、吐血、衄血、崩漏、外伤出血;
伸筋草,性味:苦、辛、温、无毒、平,具有祛风散寒、除湿消肿、舒筋活血、止咳、解毒之功效,用于治疗风寒湿痹、关节酸痛、皮肤麻木、四肢软弱、水肿、跌打损伤、黄疸、咳嗽、疮疡、疱疹、烫伤等症;
骨碎补,性味:苦、性温,具有补肾强骨、活血止痛之功效,用于治疗肾虚腰痛、足膝痿弱、耳聋、牙痛、久泄、遗尿、跌打骨折及斑秃等症;
蒲黄,性味:味甘、微辛、性平,具有止血、祛瘀、利尿之功效,用于治疗吐血、咯血、衄血、备痢、便血、崩漏、外伤出血、心腹疼痛、经闭腹痛、产后瘀痛、痛经、跌扑肿痛、血淋涩痛、带下、重舌、口疮、聤耳、阴下湿痒;
木香,性味:辛、苦、温,具有行气止痛、健脾消食之功效,用于治疗胸脘胀痛、泻痢后重、食积不消、不思饮食,煨木香实肠止泻,用于泄泻腹痛;
枸杞,性味:味甘、性平,具有养肝、滋肾、润肺之功效,用于治疗肝肾亏虚、头晕目眩、目视一清、腰膝酸软、阳痿贵精、虚劳咳嗽、消渴引饮;
黄精,性味:甘、平,具有补中益气、润心肺、强筋骨之功效,用于治疗虚损寒热、肺痨咳血、病后体虚食少、筋骨软弱、风湿疼痛、风癞癣疾等症;
独一味,性味:味甘、苦、性平,具有活血化瘀、消肿止痛之功效,用于治疗跌打、筋骨疼痛、关节肿痛、痛经、崩漏等症;
鸡血藤(烤),性味:味苦、微甘、性温,具有活血舒筋、养血调经之功效,用于治疗手足麻木、肢体瘫痪、风湿痹痛、妇女有经不调、痛经、闭经等症;
淫羊藿,性味:辛甘、温,具有补肾壮阳、祛风除湿之功效,用于治疗阳痿不举、小便淋沥、筋骨挛急、半身不遂、腰膝无力、风湿痹痛、四肢不仁等症;
红花,性味:味辛、性温,具有活血能经、祛瘀止痛之功效,用于治疗经闭、痛经、产后瘀阻腹痛、胞痹心痛症瘕积聚、跌打损伤、关节疼痛、中风偏竣、斑疹等症;
蒲公英,性味:味苦;甘、性寒,具有清热解毒、消痈散结之功效,用于治疗乳痈、肺痈、肠痈、痄腮、疔毒疮肿、目赤肿痛、感冒发热、咳嗽、咽喉肿痛、胃火、肠炎、痢疾、肝炎、胆吓炎、尿路感染、蛇虫咬伤等症;
莱菔子(炒),性味:味辛、甘、性平,具有消食导滞、降气化痰之功效,用于治疗食积气滞、脘腹胀满、腹泻、下痢后重、咳嗽多痰、气逆喘满;
桔梗,性味:苦辛、平,具有开宣肺气、祛痰排脓之功效,用于治疗外感咳嗽、咽喉肿痛、肺痈吐脓、胸满胁痛、痢疾腹痛;
甘草,性味:甘、平,具有益气补中、缓急止痛、润肺止咳、泻火解毒、调和诸药之功效,用于治疗倦怠食少、肌瘦面黄、心悸气短、腹痛便溏、四肢挛急疼痛、脏躁、咳嗽气喘、咽喉肿痛、痈疮肿痛、小儿胎毒及药物、食物中毒;
乳香,性味:味辛、苦、微温,具有活血行气、通经止痛、消肿生肌之功效,用于治疗心腹疼痛、风湿痹痛、经闭痛经、跌打瘀痛、痈疽肿毒、肠痈、疮溃不敛。
本发明药物是基于中医治疗颈椎病的原则,从依据颈椎病的病理机制及药理作用认为:就颈椎病,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的效果。
具体实施方式
本发明就是针对上述颈椎病的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个很好的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种可有效治疗颈椎病的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
连翘230g、熟地黄320g、川芎95g、肉苁蓉118g、薄荷95g、茯苓420g、厚朴95g、鹿衔草280g、伸筋草115g、骨碎补200g、蒲黄95g、木香60g、枸杞115g、黄精200g、独一味60g、鸡血藤(烤)118g、淫羊藿115g、红花95g、蒲公英260g、莱菔子(炒)95g、桔梗95g、甘草115g、乳香95g。
实施例2:
一种可有效治疗颈椎病的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
连翘260g、熟地黄350g、川芎105g、肉苁蓉130g、薄荷105g、茯苓480g、厚朴105g、鹿衔草320g、伸筋草130g、骨碎补220g、蒲黄105g、木香70g、枸杞130g、黄精230g、独一味70g、鸡血藤(烤)130g、淫羊藿130g、红花105g、蒲公英300g、莱菔子(炒)105g、桔梗105g、甘草130g、乳香105g。
实施例3:
一种可有效治疗颈椎病的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
连翘300g、熟地黄380g、川芎120g、肉苁蓉160g、薄荷120g、茯苓550g、厚朴120g、鹿衔草350g、伸筋草160g、骨碎补250g、蒲黄120g、木香80g、枸杞160g、黄精260g、独一味80g、鸡血藤(烤)160g、淫羊藿150g、红花120g、蒲公英350g、莱菔子(炒)120g、桔梗120g、甘草150g、乳香120g。
典型病例
经临床诊断治疗颈椎病患者共1260例,年龄为53岁以上的830例,只有430例为53岁以下。1260例患者中痊愈的831例,有效的328例,无效的101例。总有效率达92%。
Claims (3)
1.一种可有效治疗颈椎病的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
连翘150~300g、熟地黄120~380g、川芎50~120g、肉苁蓉100~160g、薄荷50~120g、茯苓250~550g、厚朴30~120g、鹿衔草150~350g、伸筋草90~160g、骨碎补100~250g、蒲黄50~120g、木香20~80g、枸杞50~160g、黄精150~260g、独一味30~80g、鸡血藤(烤)100~160g、淫羊藿50~150g、红花50~120g、蒲公英100~350g、莱菔子(炒)50~120g、桔梗50~120g、甘草30~150g、乳香30~120g。
2.根据权利要求1所述的可有效治疗颈椎病的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
连翘180~260g、熟地黄135~350g、川芎58~105g、肉苁蓉115~130g、薄荷58~105g、茯苓280~480g、厚朴38~105g、鹿衔草180~320g、伸筋草100~130g、骨碎补115~220g、蒲黄58~105g、木香26~70g、枸杞58~130g、黄精180~230g、独一味38~70g、鸡血藤(烤)115~130g、淫羊藿58~130g、红花58~105g、蒲公英115~300g、莱菔子(炒)58~105g、桔梗58~105g、甘草38~130g、乳香38~105g。
3.根据权利要求1至2所述的可有效治疗颈椎病的内服药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
连翘230g、熟地黄320g、川芎95g、肉苁蓉118g、薄荷95g、茯苓420g、厚朴95g、鹿衔草280g、伸筋草115g、骨碎补200g、蒲黄95g、木香60g、枸杞115g、黄精200g、独一味60g、鸡血藤(烤)118g、淫羊藿115g、红花95g、蒲公英260g、莱菔子(炒)95g、桔梗95g、甘草115g、乳香95g。
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