CN107456773A - Dried venom of toads fast decompression drying shed and its drying means - Google Patents
Dried venom of toads fast decompression drying shed and its drying means Download PDFInfo
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- CN107456773A CN107456773A CN201710878194.9A CN201710878194A CN107456773A CN 107456773 A CN107456773 A CN 107456773A CN 201710878194 A CN201710878194 A CN 201710878194A CN 107456773 A CN107456773 A CN 107456773A
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- China
- Prior art keywords
- toads
- ventilating fan
- room body
- pipe
- dried venom
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- 238000001035 drying Methods 0.000 title claims abstract description 61
- 241000269420 Bufonidae Species 0.000 title claims abstract description 54
- 239000002435 venom Substances 0.000 title claims abstract description 53
- 231100000611 venom Toxicity 0.000 title claims abstract description 53
- 210000001048 venom Anatomy 0.000 title claims abstract description 53
- 230000006837 decompression Effects 0.000 title claims abstract description 18
- 239000002002 slurry Substances 0.000 claims abstract description 30
- 239000004744 fabric Substances 0.000 claims abstract description 24
- 238000000034 method Methods 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- 230000000694 effects Effects 0.000 claims description 10
- 238000005057 refrigeration Methods 0.000 claims description 10
- 230000007423 decrease Effects 0.000 claims description 9
- 230000003247 decreasing effect Effects 0.000 claims description 7
- 229910052782 aluminium Inorganic materials 0.000 claims description 5
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 4
- 239000011888 foil Substances 0.000 claims description 4
- 230000001954 sterilising effect Effects 0.000 claims description 4
- 229920000742 Cotton Polymers 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 238000004321 preservation Methods 0.000 claims description 3
- 230000005855 radiation Effects 0.000 claims description 3
- 238000004659 sterilization and disinfection Methods 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 5
- 230000007613 environmental effect Effects 0.000 abstract description 2
- QEEBRPGZBVVINN-UHFFFAOYSA-N Desacetyl-bufotalin Natural products CC12CCC(C3(CCC(O)CC3CC3)C)C3C1(O)CCC2C=1C=CC(=O)OC=1 QEEBRPGZBVVINN-UHFFFAOYSA-N 0.000 description 14
- ATLJNLYIJOCWJE-CWMZOUAVSA-N bufogenin Chemical compound C=1([C@H]2C[C@H]3O[C@@]43[C@H]3[C@@H]([C@]5(CC[C@H](O)C[C@H]5CC3)C)CC[C@@]42C)C=CC(=O)OC=1 ATLJNLYIJOCWJE-CWMZOUAVSA-N 0.000 description 13
- 229950006858 bufogenin Drugs 0.000 description 13
- ATLJNLYIJOCWJE-UHFFFAOYSA-N resibufogenin Natural products CC12CCC(C3(CCC(O)CC3CC3)C)C3C11OC1CC2C=1C=CC(=O)OC=1 ATLJNLYIJOCWJE-UHFFFAOYSA-N 0.000 description 13
- SCULJPGYOQQXTK-OLRINKBESA-N Cinobufagin Chemical compound C=1([C@@H]2[C@@]3(C)CC[C@@H]4[C@@]5(C)CC[C@H](O)C[C@H]5CC[C@H]4[C@@]43O[C@@H]4[C@@H]2OC(=O)C)C=CC(=O)OC=1 SCULJPGYOQQXTK-OLRINKBESA-N 0.000 description 11
- SCULJPGYOQQXTK-UHFFFAOYSA-N Cinobufagin Natural products CC(=O)OC1C2OC22C3CCC4CC(O)CCC4(C)C3CCC2(C)C1C=1C=CC(=O)OC=1 SCULJPGYOQQXTK-UHFFFAOYSA-N 0.000 description 11
- 241000196324 Embryophyta Species 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 239000000463 material Substances 0.000 description 5
- 210000004907 gland Anatomy 0.000 description 4
- 239000012535 impurity Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000003245 coal Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- 241001330002 Bambuseae Species 0.000 description 1
- 241000269417 Bufo Species 0.000 description 1
- VOZHMAYHYHEWBW-NVOOAVKYSA-N Bufotalin Chemical compound C=1([C@@H]2[C@@]3(C)CC[C@@H]4[C@@]5(C)CC[C@H](O)C[C@H]5CC[C@H]4[C@@]3(O)C[C@@H]2OC(=O)C)C=CC(=O)OC=1 VOZHMAYHYHEWBW-NVOOAVKYSA-N 0.000 description 1
- VOZHMAYHYHEWBW-UHFFFAOYSA-N Bufotalin Natural products CC(=O)OC1CC2(O)C3CCC4CC(O)CCC4(C)C3CCC2(C)C1C=1C=CC(=O)OC=1 VOZHMAYHYHEWBW-UHFFFAOYSA-N 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 241001415432 Duttaphrynus melanostictus Species 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- WYTGDNHDOZPMIW-RCBQFDQVSA-N alstonine Chemical compound C1=CC2=C3C=CC=CC3=NC2=C2N1C[C@H]1[C@H](C)OC=C(C(=O)OC)[C@H]1C2 WYTGDNHDOZPMIW-RCBQFDQVSA-N 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- QEEBRPGZBVVINN-BMPKRDENSA-N bufalin Chemical compound C=1([C@H]2CC[C@]3(O)[C@H]4[C@@H]([C@]5(CC[C@H](O)C[C@H]5CC4)C)CC[C@@]32C)C=CC(=O)OC=1 QEEBRPGZBVVINN-BMPKRDENSA-N 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229930005303 indole alkaloid Natural products 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D1/00—Evaporating
- B01D1/14—Evaporating with heated gases or vapours or liquids in contact with the liquid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/65—Amphibians, e.g. toads, frogs, salamanders or newts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D1/00—Evaporating
- B01D1/0082—Regulation; Control
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D1/00—Evaporating
- B01D1/30—Accessories for evaporators ; Constructional details thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/85—Food storage or conservation, e.g. cooling or drying
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Drying Of Solid Materials (AREA)
Abstract
The invention discloses dried venom of toads fast decompression drying shed, including drying room body, door and circumference are managed, door is hinged on the wall of dry room body, it is in cubic to dry room body, and its terrace is provided with binary channels cloth bag, the air inlet of binary channels cloth bag is fixedly connected with having an area of the round mouth of pipe, have an area of and be provided with warm-air drier at the square opening of pipe, dry and be arranged with two ventilating fan I and two ventilating fan II on the wall of room body both sides, ventilating fan I is connected with horizontally disposed straight tube by blast pipe, ventilating fan II is connected with T-shaped pipe by blast pipe, the lower section of blast pipe, between the passage of binary channels cloth bag and binary channels cloth bag with being provided with least one shelf between the walls close to warm-air drier.The present invention to be dried under reduced pressure room rational in infrastructure, set up conveniently, Environmental Safety, be easily manipulated, the toad slurries progress fast decompression drying being opposite to by cooperations of binary channels cloth bag and pipeline and ventilating fan on shelf, it is ensured that the production efficiency and quality of the dried venom of toads.
Description
Technical field
The present invention relates to a kind of drying shed, is to be related to a kind of dried venom of toads fast decompression drying shed and its drying side specifically
Method.
Background technology
1995 editions《Chinese Pharmacopoeia》The animal description corresponding to the dried venom of toads：Its animal origin still has Asia toad and the flower back of the body
The animals such as toad, the commodity dried venom of toads, can also gather and process the dried venom of toads at present, but branch's amount is less, also rare in commodity, be mainly derived from China
Bufo.2000 editions, 2005 editions, 2010 editions and 2015 editions《Chinese Pharmacopoeia》Description to the dried venom of toads：This product is in Bufonidae animal
Hua Da toad or the drying secretion of Bufo melanostictus, toad is caught more than summer, season in autumn two, is cleaned, is squeezed and take ear rear gland and glandula integumentaria
White slurries（Namely toad slurries）, process, dry.The dried venom of toads is both 28 kinds of poison fiber crops issued by the State Council for needing special management
One of herbal species, and special-protection-by-the-State（Two level）One of wild animals and plants medicinal material kind, there is toxicity and two level to be on the point of
Danger animal drug double attribute.
In recent years, country constantly encourages peasant captive toad, has had thousands of artificial domestications numerous in the whole nation
The toad cultivation base grown, however, the widespread consensus of industry is, in toad breeding process, from tadpole to toadlet, toadlet into
Toad population mortality is high, is always the current problem not yet overcome.Therefore, the collection of toad magma largely still relies on field
Catch toad to carry out, the toad after collection puts back to the Nature, is advantageous to protect animal and maintaining ecological balance.It is wild between the dried venom of toads
The finiteness of resource, it must rationally be taken in using existing toad resource.
Traditional toad slurries acquisition technique, it is to be extruded after wrapping up toad ear rear gland with oilpaper with hand to offer record according to Gu, is made
Slurries outflow is bonded on oilpaper, is removed after drying, though yield is low, impurity and moisture are few, and quality is high；Generally used now adopts slurry processes
It is to use metal（Aluminium, copper）Fixture directly presss from both sides toad ear rear gland body and skin body of gland, slurries is reserved skin surface, then uses bamboo again
The slurries on skin are scraped after piece or metal, easily and fast, yield is high, with the price more and more higher of the dried venom of toads, in profit for this method
Adopting slurry under benefit driving, metal fixture is immersed in clear water by person together with the toad magma in fixture, adds the water in toad magma
Point, or even the doping behavior for the bad retailer's subject intent having, what is also had even buys magma from strange land, takes place of production sale,
In addition, toad magma collection and commodity dried venom of toads process in, exist " adopting slurry, person does not process, sell magma, processor purchase
Magma is directly processed " phenomenon.In addition, the material such as toad blood contained in slurries, water, amino acid, protein is mould
The culture medium of growth, slurries are easy to go mouldy under the conditions of water content is suitable, while mixed impurity in slurries（Skin chips,
Silt and phytoclasts etc.）Also result in its go mouldy, corrupt iso-metamorphism phenomenon.
Influence ［ J ］ Chinese experimental pharmacology of traditional Chinese medical formulae magazine of the red places of production of Yuan Xujiang, Shen Jiayin, Wu Yan to dried venom of toads quality of medicinal material,
2010,16（4）:In 12 samples disclosed in 75, only 2 sample sizes reach《Chinese Pharmacopoeia》It is required that；Qu Ting, Gao Huimin,
The content of indole alkaloid and bufotalin constituents ［ J ］ CHINA JOURNAL OF CHINESE MATERIA MEDICAs in the toad class medicinal materials such as old two silk floss, 2012,
37（20）:In 11 samples disclosed in 3086, only 5 sample sizes reach《Chinese Pharmacopoeia》It is required that；Domestic 17 big medicinal material cities
Field also is difficult to buy the qualified commodity dried venom of toads, 2000 editions《Chinese Pharmacopoeia》Start the character to the dried venom of toads, resibufogenin and magnificent toad
The quantitative requirement of the total content of crisp malicious base, detailed is described as：This product is in oblate lumps or sheet, resibufogenin and China
Bufalin total amount must not be less than 6%；2010 editions《Chinese Pharmacopoeia》Start the quantitative requirement having to dried venom of toads water content, detailed
It is described as：Moisture must not cross 13%.As not in time be well mixed, impurity screening, drying, except winter, other seasons are difficult to make toad
Crisp character（Especially oblate lumps）, moisture, the total amount of resibufogenin and Cinobufagin reach《Chinese Pharmacopoeia》
Standard, influences the quality of dried venom of toads finished product, and is unfavorable for the storage, keeping and transport of the dried venom of toads.
Currently used drying means is mainly based on the drying of the open firings such as Indoor Natural airing and coal, the former time
Longer, the uniformity of the latter's temperature and humidity in whole interior is not fine, and the naked light such as coal had burnt both not environmentally, also not
Safety.
The content of the invention
The technical problems to be solved by the invention are to provide a kind of dried venom of toads fast decompression drying shed and its drying means, with right
Slurries carry out rapid draing, and effectively improve the quality of dried venom of toads finished product.
In order to solve the above technical problems, the technical solution adopted by the present invention is：
Dried venom of toads fast decompression drying shed, including dry room body, door and circumference pipe, door and be hinged on the wall of dry room body,
It is in cubic to dry room body, and its terrace is provided with binary channels cloth bag, the round mouth of the air inlet and circumference pipe of binary channels cloth bag
It is fixedly connected, has an area of and warm-air drier is provided with the square opening of pipe, dries and be arranged with two ventilating fan I and two on the wall of room body both sides
Platform ventilating fan II, ventilating fan I are connected with horizontally disposed straight tube by blast pipe, are provided with the top and bottom of straight tube some logical
Hole, ventilating fan II are connected with T-shaped pipe by blast pipe, and the horizontal part of T-shaped pipe aligns with straight tube, vertical component effect is parallel with blast pipe,
Some through holes are provided with the top of blast pipe, between the lower section of blast pipe, the passage of binary channels cloth bag and binary channels cloth bag is with leaning on
Nearly warm-air drier is provided with least one shelf between the walls, if the top and bottom of T-shaped pipe are provided with addition to the part of face shelf
The both ends of dry through hole, the both ends of straight tube and T-shaped pipe vertical component effect are closed by plug, and warm-air drier, ventilating fan I and ventilating fan II pass through
Control cabinet is controlled, and control cabinet is fixed on the wall of dry room body.
Further, refrigeration plant is additionally provided with the terrace of above-mentioned dry room body, refrigeration plant is controlled by control cabinet.
Further, the diameter of the passage of above-mentioned binary channels cloth bag gradually successively decreases from air inlet to afterbody.
Further, a diameter of 250-300mm of above-mentioned straight tube, T-shaped pipe and blast pipe, and with drying the day at the top of room body
The distance between face is 150-300mm.
Further, the aperture of through hole is gradually successively decreased along wind direction on above-mentioned straight tube, spacing is gradually incremented by along wind direction, T-shaped pipe
The aperture of through hole is gradually successively decreased along wind direction on horizontal part, spacing is gradually incremented by along wind direction, the aperture edge of through hole on T-shaped pipe vertical component effect
Wind direction gradually successively decreases, spacing along wind direction gradually be incremented by, on blast pipe the aperture of through hole gradually successively decrease along wind direction, spacing along wind direction by
Gradually it is incremented by.
Further, it is filled with heat-preservation cotton in the wall of above-mentioned dry room body, terrace and terrace.
The method being dried using above-mentioned dried venom of toads fast decompression drying shed, is comprised the following steps：
（1）Toad slurries after hybrid filtering are uniformly applied on the thick plastic plates of 0.3-0.5mm, the smearing of toad slurries is thick
Spend for 4-12mm, then plastic plate is contained on pallet, pallet is placed on the shelf in drying shed body；
（2）Start warm-air drier, adjust its temperature be 20-75 DEG C, power 6-22Kw, voltage 380V, while start four row
Fan, toad slurries are made to be dried to the dried venom of toads under subnormal ambient, each ventilating fan is by the pattern for starting 1-2 minutes, stopping 8-9 minutes
Work；
（3）When the water content of the dried venom of toads reaches 10-12.9% after to be dried, warm-air drier and each ventilating fan are closed, starts refrigeration plant,
Temperature in drying shed body is down to below outdoor temperature；
（4）The dried venom of toads is peeled off from plastic plate, is encapsulated in aluminum foil compound bag, radiation sterilization is encapsulated in aluminum foil compound bag, spoke
It is stored in after penetrating sterilizing in 0 ± 18 DEG C of warehouse.
As preferable, above-mentioned steps（2）The temperature adjustment of middle warm-air drier is 40 DEG C.
As preferable, above-mentioned steps（1）The smearing thickness of middle toad slurries is 4-8mm.
It is an advantage of the invention that：The present invention to be dried under reduced pressure room rational in infrastructure, set up conveniently, Environmental Safety, be easily manipulated,
The toad slurries being opposite to by the cooperation of binary channels cloth bag and pipeline and ventilating fan on shelf carry out fast decompression drying, can
Farthest retain the composition of resibufogenin and Cinobufagin, it is ensured that the production efficiency and quality of the dried venom of toads, have notable
Practicality.
Brief description of the drawings
The present invention is described in further detail with reference to the accompanying drawings and detailed description.
Fig. 1 is the structural representation of the present invention；
Fig. 2 is the arrangement schematic diagram of pipeline and binary channels cloth bag in the present invention；
Fig. 3 is the arrangement schematic diagram of shelf in the present invention.
Wherein, 1 room body, is dried, 2, control cabinet, 3, shelf, 4, warm-air drier, 41, circumference pipe, 5, binary channels cloth bag, 6, logical
Hole, 7, door, 8, refrigeration plant, 9, ventilating fan I, 91, ventilating fan II, 10, straight tube, 11, T-shaped pipe, 12, plug, 13, exhaust
Pipe.
Embodiment：
As shown in Figure 1 to Figure 3, dried venom of toads fast decompression drying shed, including dry room body 1, door 7 and circumference pipe 41, door 7 and be hinged
On the wall for drying room body 1, it is in cubic to dry room body 1, and its terrace is provided with binary channels cloth bag 5, binary channels cloth bag 5
Air inlet with have an area of pipe 41 round mouth be fixedly connected, have an area of pipe 41 square opening at be provided with warm-air drier 4, warm-air drier 4 is apart from wall
There is a certain distance so that the air dried in room body 1 can shorten drying time, dry 1 liang of room body constantly by circulating-heating
Two ventilating fan I9 and two ventilating fan II91 are arranged with the wall of side, ventilating fan I9 is connected with level by blast pipe 13
The straight tube 10 of setting, the top and bottom of straight tube 10 are provided with some through holes 6, and ventilating fan II91 is connected with T-shaped by blast pipe 13
Pipe 11, the horizontal part of T-shaped pipe 11 aligns with straight tube 10, vertical component effect is parallel with blast pipe 13, and the top of blast pipe 13 is provided with some
Through hole 6, between the lower section of blast pipe 13, the passage of binary channels cloth bag 5 and binary channels cloth bag 5 with close to warm-air drier 4 wall
Between be provided with least one shelf 3, be coated with the plastic plates of toad slurries for placing, the top and bottom of T-shaped pipe 11 are except just
To being provided with some through holes 6 outside the part of shelf 3 so that the dried venom of toads will not be ftractureed by airflow influence, the both ends of straight tube 10 and T-shaped pipe
The both ends of 11 vertical component effects are closed by plug 12, and warm-air drier 4, ventilating fan I9 and ventilating fan II91 are controlled by control cabinet 2, control
Case 2 is fixed on the wall of dry room body 1.
A diameter of 250-300mm of straight tube 10, T-shaped pipe 11 and blast pipe 13, and between the terrace with drying the top of room body 1
Distance be 150-300mm, the aperture of through hole 6 is gradually successively decreased along wind direction on straight tube 10, spacing is gradually incremented by along wind direction, T-shaped pipe
The aperture of through hole 6 is gradually successively decreased along wind direction on 11 horizontal parts, spacing is gradually incremented by along wind direction, through hole 6 on the T-shaped vertical component effect of pipe 11
Aperture is gradually successively decreased along wind direction, spacing along wind direction gradually be incremented by, on blast pipe 13 aperture of through hole 6 gradually successively decrease along wind direction,
Away from gradually incremental along wind direction.
Dry and be additionally provided with refrigeration plant 8 on the terrace of room body 1, refrigeration plant 8 controls also by control cabinet 2；Dry room body 1
Wall, be filled with heat-preservation cotton in terrace and terrace, improve the heat-insulating property for drying room body 1, while be also beneficial to reduction energy consumption.
The method being dried using above-mentioned dried venom of toads fast decompression drying shed, is comprised the following steps：
（1）Toad slurries after hybrid filtering are uniformly applied on the thick plastic plates of 0.3-0.5mm, the smearing of toad slurries is thick
Spend for 4-12mm（Preferably 4-8mm）, then plastic plate is contained on pallet, the shelf 3 that pallet is placed in dry room body 1
On；
（2）Start warm-air drier 4, adjust its temperature as 20-75 DEG C（Preferably 40 DEG C）, power 6-22Kw（Preferably 18-
22Kw）, voltage 380V, while start four ventilating fans, toad slurries is dried to the dried venom of toads, each ventilating fan under subnormal ambient
Worked by starting 1-2 minutes, stopping the pattern of 8-9 minutes, keep indoor overall humidity, temperature to match, to reduce artificial behaviour
That makees is cumbersome, can pass through the installation loop control time relay realization in control cabinet 2；Due to the passage of binary channels cloth bag 5
Diameter gradually successively decreases from air inlet to afterbody, it is ensured that dries uniformity of the temperature in room body 1 in whole space；
（3）When the water content of the dried venom of toads reaches 10-12.9% after to be dried, warm-air drier 4 and each ventilating fan are closed, starts refrigeration plant
8, the temperature dried in room body 1 to be down to below outdoor temperature, it is ensured that the water content of the dried venom of toads can reach minimum degree otherness, and
Easily the dried venom of toads is peeled off from plastic plate, before stripping operation is carried out, binary channels cloth bag 5 can be collapsed to circumference pipe 41, with
Convenient to operate personnel walk about；
（4）The dried venom of toads is easily peeled off under the elastic reaction of plastic plate, is encapsulated in aluminum foil compound bag, is stored in after radiation sterilization
In 0 ± 18 DEG C of warehouse.
Between when drying it is long cause dried venom of toads water content be less than 10% when, start four ventilating fans in arbitrary 1-2 platforms,
Uniform moisture in outdoor air is introduced in dry room body 1, closed when the water content of the dried venom of toads reaches 10-12.9% again
Close, you can carry out the stripping operation of the dried venom of toads, it is ensured that the quality of the dried venom of toads.
40 DEG C of airing, 40 DEG C of drying and the present invention are dried under reduced pressure dried venom of toads moisture under three kinds of drying regimes indoors
（%）Be determined as follows shown in table 1：
Table 1；
Resibufogenin content under three kinds of drying regimes（%）Be determined as follows shown in table 2：
Table 2；
Cinobufagin content under three kinds of drying regimes（%）Be determined as follows shown in table 3：
Table 3；
Resibufogenin and Cinobufagin total content under three kinds of drying regimes（%）Be determined as follows shown in table 4：
Table 4.
As can be seen here, 40 DEG C are dried under reduced pressure the more indoor airing 10d of 24h moistures, 40 DEG C of decrease speeds for drying 5d more
It hurry up；After indoor airing 10d, after 40 DEG C of drying 5d and 40 DEG C be dried under reduced pressure 24h after moisture be attained by requirement, but 40 DEG C subtract
The efficiency for pressing dry dry 24h is significantly higher than indoor airing and 40 DEG C of drying.
Above-mentioned three kinds of drying means can make in the dried venom of toads content of resibufogenin and Cinobufagin with drying time
Extension be in overall downward trend.Cinobufagin is different from resibufogenin composition, using indoor airing, 40 DEG C drying and
40 DEG C when being dried under reduced pressure three kinds of drying means, with the extension of drying time, the change for first raising and declining afterwards is presented in corresponding content
Change, show that toad slurries resibufogenin and Cinobufagin composition during the dried venom of toads is dried to can be hydrolyzed into other productions
Thing.
Meanwhile resibufogenin and Cinobufagin total content are both greater than in the obtained dried venom of toads of above-mentioned three kinds of drying means
6.0%, reach《Chinese Pharmacopoeia》Regulation, and in the case of moisture identical, resibufogenin and Cinobufagin always contain
Measure and be dried under reduced pressure for 40 DEG C>40 DEG C of drying>Indoor airing, this species diversity are that processor and researcher are quite unexpected.
The factors such as resibufogenin and Cinobufagin content, cost and operation difficulty are considered, using the present invention
To be dried under reduced pressure room especially pronounced to the drying effect of the sizable toad slurries of moisture, and can effectively reduce toad slurry
Liquid time of contact with air in the drying process, reduce the loss that resibufogenin and Cinobufagin aoxidize in atmosphere
Amount.
Claims (9)
1. dried venom of toads fast decompression drying shed, it is characterised in that：It is hinged on including drying room body, door and circumference pipe, the door
On the wall for drying room body, the dry room body is in cubic, and its terrace is provided with binary channels cloth bag, the binary channels cloth
The air inlet of bag is fixedly connected with having an area of the round mouth of pipe, and warm-air drier, the dry room body two are provided with the square opening of the circumference pipe
Two ventilating fan I and two ventilating fan II are arranged with the wall of side, the ventilating fan I is connected with level by blast pipe and set
The straight tube put, some through holes are provided with the top and bottom of the straight tube, the ventilating fan II is connected with T-shaped pipe by blast pipe,
The horizontal part of the T-shaped pipe is alignd with straight tube, vertical component effect is parallel with blast pipe, and some through holes are provided with the top of the blast pipe,
Binary channels cloth bag and being provided with close to warm-air drier between the lower section of the blast pipe, the passage of binary channels cloth bag and between the walls
At least one shelf, the top and bottom of the T-shaped pipe are provided with some through holes in addition to the part of face shelf, and the two of the straight tube
End and the both ends of T-shaped pipe vertical component effect are closed by plug, and the warm-air drier, ventilating fan I and ventilating fan II are controlled by control cabinet,
The control cabinet is fixed on the wall of dry room body.
2. dried venom of toads fast decompression drying shed according to claim 1, it is characterised in that：On the terrace of the dry room body also
Provided with refrigeration plant, the refrigeration plant is controlled by control cabinet.
3. dried venom of toads fast decompression drying shed according to claim 1, it is characterised in that：The passage of the binary channels cloth bag
Diameter gradually successively decreases from air inlet to afterbody.
4. dried venom of toads fast decompression drying shed according to claim 1, it is characterised in that：The straight tube, T-shaped pipe and blast pipe
A diameter of 250-300mm, and be 150-300mm with drying the distance between terrace at the top of room body.
5. dried venom of toads fast decompression drying shed according to claim 1, it is characterised in that：The aperture edge of through hole on the straight tube
Wind direction gradually successively decreases, spacing along wind direction gradually be incremented by, on the T-shaped pipe horizontal part aperture of through hole gradually successively decrease along wind direction,
Away from being gradually incremented by along wind direction, the aperture of through hole is gradually successively decreased along wind direction on the T-shaped pipe vertical component effect, spacing is gradually passed along wind direction
Increase, the aperture of through hole is gradually successively decreased along wind direction on the blast pipe, spacing is gradually incremented by along wind direction.
6. dried venom of toads fast decompression drying shed according to claim 1, it is characterised in that：Wall, the day of the dry room body
Heat-preservation cotton is filled with face and terrace.
7. the method being dried using dried venom of toads fast decompression drying shed according to any one of claim 1 to 6, it is special
Sign is：Comprise the following steps：
（1）Toad slurries after hybrid filtering are uniformly applied on the thick plastic plates of 0.3-0.5mm, the smearing of toad slurries is thick
Spend for 4-12mm, then plastic plate is contained on pallet, pallet is placed on the shelf in drying shed body；
（2）Start warm-air drier, adjust its temperature be 20-75 DEG C, power 6-22Kw, voltage 380V, while start four row
Fan, toad slurries are made to be dried to the dried venom of toads under subnormal ambient, each ventilating fan is by the pattern for starting 1-2 minutes, stopping 8-9 minutes
Work；
（3）When the water content of the dried venom of toads reaches 10-12.9% after to be dried, warm-air drier and each ventilating fan are closed, starts refrigeration plant,
Temperature in drying shed body is down to below outdoor temperature；
（4）The dried venom of toads is peeled off from plastic plate, is encapsulated in aluminum foil compound bag, 0 ± 18 DEG C of warehouse is stored in after radiation sterilization
In.
8. drying means according to claim 7, it is characterised in that：The step（2）The temperature adjustment of middle warm-air drier is
40℃。
9. drying means according to claim 7, it is characterised in that：The step（1）The smearing thickness of middle toad slurries
For 4-8mm.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108815196A (en) * | 2018-08-30 | 2018-11-16 | 上海和黄药业有限公司 | A kind of processing method of the Chinese medicine dried venom of toads |
| CN109481471A (en) * | 2019-01-25 | 2019-03-19 | 上海真仁堂药业有限公司 | The preparation method of dried venom of toads powder medicine materical crude slice |
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|---|---|---|---|---|
| CN204830791U (en) * | 2015-07-31 | 2015-12-02 | 广州力为节能技术有限公司 | Photoelectricity heat accumulation drying shed |
| CN105902574A (en) * | 2016-06-03 | 2016-08-31 | 四川仟源中药饮片有限公司 | Single-dosage package arenobufagin and preparation method thereof |
| CN206176964U (en) * | 2016-10-18 | 2017-05-17 | 天津京泊模具铸造有限公司 | Drying chamber cooling device |
| CN207237311U (en) * | 2017-09-26 | 2018-04-17 | 杨鸣泽 | Dried venom of toads fast decompression drying shed |
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2017
- 2017-09-26 CN CN201710878194.9A patent/CN107456773B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN204830791U (en) * | 2015-07-31 | 2015-12-02 | 广州力为节能技术有限公司 | Photoelectricity heat accumulation drying shed |
| CN105902574A (en) * | 2016-06-03 | 2016-08-31 | 四川仟源中药饮片有限公司 | Single-dosage package arenobufagin and preparation method thereof |
| CN206176964U (en) * | 2016-10-18 | 2017-05-17 | 天津京泊模具铸造有限公司 | Drying chamber cooling device |
| CN207237311U (en) * | 2017-09-26 | 2018-04-17 | 杨鸣泽 | Dried venom of toads fast decompression drying shed |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108815196A (en) * | 2018-08-30 | 2018-11-16 | 上海和黄药业有限公司 | A kind of processing method of the Chinese medicine dried venom of toads |
| CN109481471A (en) * | 2019-01-25 | 2019-03-19 | 上海真仁堂药业有限公司 | The preparation method of dried venom of toads powder medicine materical crude slice |
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Effective date of registration: 20230221 Address after: No. 22, Group 25, Changlai Village, Changle Town, Haimen District, Nantong City, Jiangsu Province, 226100 Applicant after: Yangyitang Toad Farm in Haimen District Address before: 226100 No. 546, Xiushan West Road, Hi-tech Zone, Haimen Town, Haimen City, Nantong City, Jiangsu Province (Haimen Kangquan Chanyi Technology Co., Ltd.) Applicant before: Yang Mingze |
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