CN107441393A - It is a kind of to be used to treat pill medicine of lung cancer and preparation method thereof - Google Patents

Abstract

The invention belongs to field of traditional Chinese, it is therefore an objective to which a kind of pill medicine for being used to treat lung cancer provided according to the understanding mechanism of Chinese traditional treatment lung cancer, each component and its mass parts ratio of the medicine are as follows：150~260g of cutworm, 150~350g of Sculellaria barbata, 50~150g of Dysosma versipellis, 250~550g of little groundcherry herb or fruit, 150~500g of black nightshade, 250~500g of sealwort, 30~100g of levisticum, 200~550g of cultivated land, 200~550g of medical stone, 15~35g of indigo naturalis, 90~350g of rhizoma imperatae, 30~100g of Fructus Aurantii, 60~100g of lophatherum gracile, 50~100g of radix glehniae, 50~160g of barrenwort, 90~350g of coix seed, 60~150g of the tuber of dwarf lilyturf, 60~150g of the capsule of weeping forsythia, 30~100g of the membrane of a chicken's gizzard, 60~100g of madder, 150~350g of oldenlandia diffusa, 90~350g of the Radix Astragali, 60~150g of the bighead atractylodes rhizome；Medicine provided by the invention is a good Chinese prescription.

Description

It is a kind of to be used to treat pill medicine of lung cancer and preparation method thereof

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of pill medicine for being used to treat lung cancer, particularly for lung The field of the pill medicine that cancer patient uses and preparation method thereof.

Background technology

Doctor thinks：Lung cancer is that morbidity and mortality growth is most fast, and maximum to population health and life threat is pernicious One of tumour.Many countries all report that the morbidity and mortality of lung cancer substantially increase in the past 50 years, the male lung cancer incidence of disease First of all malignant tumours is accounted for the death rate, the women incidence of disease accounts for second, and the death rate accounts for second.The cause of disease of lung cancer So far not completely clearly, great mass of data shows, long-term a large amount of smokings and lung cancer have very close relationship.It is existing Research has shown that：The probability that long-term a large amount of smokers suffer from lung cancer is 10~20 times of non-smoker, and it is smaller to start the age of smoking, suffers from The probability of lung cancer is higher.In addition, smoking not only directly affects my health, the also health generation to surrounding population is bad Influence, cause involuntary smoker's lung cancer illness rate substantially to increase.The incidence of disease of city dweller's lung cancer is higher than rural area, and this may be with city City's atmosphere pollution with flue dust contain carcinogen it is relevant.

So, it is that those skilled in the art will urgently solve with regard to how to find a kind of Chinese medicine composition for imitating treatment lung cancer Certainly the problem of.

The content of the invention

With the continuous development of China's traditional Chinese medicine, in treatment lung cancer, people gradually appreciate Chinese traditional treatment lung The advantages of cancer, and good effect, the advantage such as quick, toxic side effect is small over the course for the treatment of, for existing western medical treatment lung cancer Present situation, the purpose of the present invention are to be to provide a kind of pill medicine for being used to treat lung cancer, are recovered early with solving patients with lung cancer The problem of healthy.The medicine is using common Chinese medicine as raw material, by selecting rational medicine and mass parts ratio, can effectively be treated Above-mentioned lung cancer one is demonstrate,proved.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：There is provided a kind of for treating lung cancer Pill medicine and preparation method thereof, it is characterised in that each component and its mass parts of the medicine are than as follows：

150~260g of cutworm, 150~350g of Sculellaria barbata, 50~150g of Dysosma versipellis, 250~550g of little groundcherry herb or fruit, black nightshade 150~ 500g, 250~500g of sealwort, 30~100g of levisticum, 200~550g of cultivated land, 200~550g of medical stone, 15~35g of indigo naturalis, 90~350g of rhizoma imperatae, 30~100g of Fructus Aurantii, 60~100g of lophatherum gracile, 50~100g of radix glehniae, 50~160g of barrenwort, Job's tears 90~350g of benevolence, 60~150g of the tuber of dwarf lilyturf, 60~150g of the capsule of weeping forsythia, 30~100g of the membrane of a chicken's gizzard, 60~100g of madder, oldenlandia diffusa 150~350g, 90~350g of the Radix Astragali, 60~150g of the bighead atractylodes rhizome, auxiliary material：Appropriate starch.

It is a kind of to be used to treat pill medicine of lung cancer and preparation method thereof, it is characterised in that each component of the medicine And its mass parts are than as follows：

180~230g of cutworm, 180~310g of Sculellaria barbata, 58~130g of Dysosma versipellis, 280~480g of little groundcherry herb or fruit, black nightshade 180~ It is 430g, 280~420g of sealwort, 38~90g of levisticum, 260~480g of cultivated land, 260~480g of medical stone, 18~31g of indigo naturalis, white 100~310g of lalang grass rhizome, 38~90g of Fructus Aurantii, 70~90g of lophatherum gracile, 58~90g of radix glehniae, 58~140g of barrenwort, coix seed 100~310g, 70~130g of the tuber of dwarf lilyturf, 70~130g of the capsule of weeping forsythia, 38~90g of the membrane of a chicken's gizzard, 70~90g of madder, oldenlandia diffusa 180~ 310g, 100~310g of the Radix Astragali, 70~130g of the bighead atractylodes rhizome, auxiliary material：Appropriate starch.

It is a kind of to be used to treat pill medicine of lung cancer and preparation method thereof, it is characterised in that the medicine of " preferred plan " The each component and its mass parts of thing are than as follows：

It is cutworm 200g, Sculellaria barbata 280g, Dysosma versipellis 115g, little groundcherry herb or fruit 420g, black nightshade 380g, sealwort 380g, levisticum 80g, ripe Ground 420g, medical stone 420g, indigo naturalis 28g, rhizoma imperatae 280g, Fructus Aurantii 80g, lophatherum gracile 80g, radix glehniae 80g, barrenwort 120g, Coix seed 280g, tuber of dwarf lilyturf 115g, capsule of weeping forsythia 115g, the membrane of a chicken's gizzard 80g, madder 80g, oldenlandia diffusa 280g, Radix Astragali 280g, the bighead atractylodes rhizome 115g, auxiliary material：Appropriate starch.

It is a kind of to be used to treat pill medicine of lung cancer and preparation method thereof, it is characterised in that methods described includes following step Suddenly it is prepared：

A, except medical stone（Water cooling is added to invade）Outside, after above-mentioned other raw material Chinese medicines being picked into impurity and dust, according to mass parts than altogether Grind for superfine end it is stand-by；

B, the method for preparing Chinese kmedicine bolus agent according to tradition, after ground superfine myrrh thing and starch sieving, it is put into medicine device Middle mixing is mixed, and during pill, one side pill sprays medical stone soak on one side, it is prepared into water-bindered pill agent（The granularity of its water-bindered pill is： 3.8mm~4.0mm）, and then dry, packing dress sealing.

It is a kind of to be used to treat pill medicine of lung cancer and preparation method thereof, it is characterised in that the instructions of taking is：Will system The water pill medicine got ready is three times a day to take, and once a dose in the morning, afternoon and evening, and dosage 8g/time, warm water delivery service.It is within 30 days One course for the treatment of, 5~6 courses for the treatment of of taking medicine, sb.'s illness took a favorable turn, and pain mitigates, so as to extend the life cycle of patient.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Cutworm, nature and flavor：It is sweet, flat, there is the effect of kidney-nourishing moistening lung, nourishing yin and supplementing blood, clearing heat and relieving fidgetness, coughed for treating pulmonary tuberculosis, The diseases such as deficiency syndrome of the lung asthma, haematemesis, night sweat, anaemia, infantile malnutrition；

Sculellaria barbata, nature and flavor：It is pungent, bitter, cold, there is the effect of clearing heat and detoxicating, stagnation resolvation diuresis, for treating furuncle swelling toxin, throat swells Bitterly, the disease such as venomous snake bite, the pain of injury caused by falling and tumbling, oedema, jaundice；

Dysosma versipellis, nature and flavor：It is sweet, bitter, cool, it is slightly poisonous, there is the effect of clearing heat and detoxicating, promoting blood circulation and removing blood stasis, stung for treating poisonous snake The diseases such as worm snake bite, ulcerative carbuncle furuncle, lymphnoditis, parotitis, breast cancer are controlled in wound, traumatic injury, external application；

Little groundcherry herb or fruit, nature and flavor：Cold in nature, bitter, have excreting dampness, desinsection the effect of, for treat jaundice, difficult urination, chronic cough and asthma, The diseases such as infantile malnutrition due to digestive disturbances or intestinalparasites disease, scrofula, epidemic blisters, wet sore；

Black nightshade, nature and flavor：It is bitter, cold, it is slightly poisonous, there is the effect of controlling clearing heat and detoxicating, inducing diuresis for removing edema, for treating cat fever, tooth Bitterly, carbuncle boils boils, pemphigus, snake bite are controlled in chronic bronchitis, dysentery, urinary infection, mastitis, leukorrhea, cancer, external application Deng disease；

Sealwort, nature and flavor：Cold in nature, bitter, it is nontoxic, there is the effect of excreting dampness, desinsection, for treating jaundice, difficult urination, chronic Cough and asthma, infantile malnutrition due to digestive disturbances or intestinalparasites disease, scrofula, epidemic blisters, wet sore；

Levisticum, nature and flavor：Pungent, bitter, tepor, there is the effect of dispelling wind and eliminating dampness, numbness relieving and pain relieving, for treating wind-cold-dampness arthralgia, waist and knee pain Bitterly, few the moon volt wind headache；

Cultivated land, nature and flavor：Sweet, tepor, have nourishing yin and supplementing blood, beneficial to spirit and marrow the effect of, for treat the deficiency of liver-yin and kidney-yin, soreness and weakness of waist and knees, Osteopyrexia and fever, night sweat seminal emission, Heat Diabetes, blood deficiency chlorosis, palpitation and severe palpitation, irregular menstruation, metrostaxis, dizziness, tinnitus, beard and hair Early white, radix rehmanniae recen adds yellow rice wine to mix to steam black, glossy to interior exogenic color, or directly steam to black profit and form, abbreviation cultivated land, cut sheet use；

Medical stone, nature and flavor：It is sweet, warm, it is nontoxic, have detoxicating and resolving a mass, remove necrosis and promote granulation, except cold clearing damp, beneficial liver and strengthening stomach, it is promoting blood circulation and removing blood stasis, Diuresis fossil, the effect of promoting longevity, for treat ulcer carbuncle on the back, acne, eczema, tinea pedis, prickly heat, finger chap, chloasma, Toothache, canker sore, arthralgia pain due to rheumatism, lumbago, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound are red and swollen, high Blood pressure, senile vascular sclerosis, tumour, lithangiuria；

Indigo naturalis, nature and flavor：It is salty, cold, there is the effect of clearing heat and detoxicating, cool blood, arresting convulsion, for treating febrile virulent maculae, blood-head tells nosebleed, chest The diseases such as pain hemoptysis, aphtha, mumps, larynx numbness, pediatric epilepsy scared；

Rhizoma imperatae, nature and flavor：It is sweet, cold, have cooling blood and hemostasis, reducing fever and causing diuresis the effect of, for treat blood-head haematemesis, bleeding from five sense organs or subcutaneous tissue, hematuria, Pyreticosis polydipsia, jaundice, oedema, puckery pain of heat gonorrhea, acute nephritis edema；

Fructus Aurantii, nature and flavor：It is bitter, pungent, sour, warm, there is the effect of regulating the flow of QI to ease the stomach, row stagnant dissipate-swelling, for treating the chest side of body stagnation of the circulation of vital energy, turgor pain Bitterly, accumulation of food in the stomach and intes tine due to indigestion, stop in phlegm and retained fluid, gastroptosis, prolapse of the anus, sub-official prolapses；

Lophatherum gracile, nature and flavor：It is sweet, light, cold, there is the effect of clearing heat and relieving fidgetness, diuresis, for treating pyreticosis polydipsia, hot urination leaching Bitterly, aphthae；

Radix glehniae, nature and flavor：Sweet, slight bitter, it is slightly cold, there is the effect of nourishiing yin to clear away the lung-heat, reinforcing stomach reg fluid, for treating lung-heat type cough, labor Cough phlegm blood, pyreticosis injury thirst；

Barrenwort, nature and flavor：Xin Gan, temperature, there is the effect of tonifying kidney and strengthening yang, dispelling wind and eliminating dampness, do not lifted for treating impotence, urine leaching The diseases such as drip, muscles and bones contraction urgency, hemiplegia, waist-leg weakness, arthralgia pain due to rheumatism, four limbs are meciless；

Coix seed, nature and flavor：It is sweet, light, cool, there is the effect of invigorating the spleen excreting dampness, remove numbness antidiarrheal, dense heat-clearing row, for treating oedema, pin Gas, difficult urination, arthritis with fixed pain caused by dampness contraction, splenasthenic diarrhea, lung carbuncle, acute appendicitis, flat wart；

The tuber of dwarf lilyturf, nature and flavor：Sweet, slight bitter, it is slightly cold, there is the effect of nourishing Yin and promoting production of body fluid, moistening lung clears away heart-fire, for treating dryness of the lung dry cough, consumptive disease The diseases such as cough, injury thirst, vexed insomnia, Heat Diabetes, dry constipation of intestines, pharyngeal diphtheria；

The capsule of weeping forsythia, nature and flavor：Bitter, cold nature, there is the effect of clearing heat and detoxicating, dispersing swelling and dissipating binds, for treating anemopyretic cold, warm disease, heat Drench the diseases such as renal shutdown, ulcer, pyogenic infections, scrofula, goiter and tumor, larynx numbness；

The membrane of a chicken's gizzard, nature and flavor：It is sweet, flat, have stomach strengthening and digestion promoting, arresting seminal emission the effect of, for treat dyspepsia, vomiting dysentery, The diseases such as infantile malnutrition, the enuresis, seminal emission；

Madder, nature and flavor：It is bitter, cold, there is cool blood, hemostasis, dissolving stasis, the effect of stimulating the menstrual flow, for treating haematemesis, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, wound Bleeding, Amenorrhea stasis blocking, joint pain, tumbling and swelling；

Oldenlandia diffusa, nature and flavor：Bitter sweet, tremble with fear, be nontoxic, there is the effect of clearing heat and detoxicating, dampness removing, for treating dyspnea and cough due to lung-heat, pharynx The diseases such as larynx swelling and pain, acute appendicitis, furuncle sore, venomous snake bite, puckery pain of heat gonorrhea, oedema, dysentery, enteritis, jaundice with damp-heat pathogen, cancerous swelling；

The Radix Astragali, nature and flavor：Sweet, tepor, there is the effect of invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation, for treating the deficiency of vital energy Weak, anorexia and loose stool, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, The diseases such as flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic rephrilis protinuria, diabetes；

The bighead atractylodes rhizome, nature and flavor：It is bitter, sweet, warm, have strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, it is antiabortive the effect of, for treating insufficiency of the spleen food Less, it is abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritability, Rhizoma Atractylodis Macrocephalae invigorating the spleen and stomach, antiabortive, for spleen eating less, let out Rush down loose stool, fetal irritability.

Medicine of the present invention is the principle based on Chinese traditional treatment lung cancer, is recognized from the pathomechanism according to lung cancer and pharmacological action For：With regard to lung cancer, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment effect well to above-mentioned disease Fruit.

Embodiment

A kind of Chinese medicine preparation that the present invention proposes aiming at the treatment of above-mentioned lung cancer, the medicine prepared using the formula Good drug efficacy, it is quick, it is a Chinese prescription treated both principal and secondary aspect of disease, is particularly suitable for Clinical practice.With reference to the specific of the present invention Embodiment is described in further detail：

Embodiment 1：

A kind of pill medicine for being used to treat lung cancer, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown：

It is cutworm 200g, Sculellaria barbata 280g, Dysosma versipellis 115g, little groundcherry herb or fruit 420g, black nightshade 380g, sealwort 380g, levisticum 80g, ripe Ground 420g, medical stone 420g, indigo naturalis 28g, rhizoma imperatae 280g, Fructus Aurantii 80g, lophatherum gracile 80g, radix glehniae 80g, barrenwort 120g, Coix seed 280g, tuber of dwarf lilyturf 115g, capsule of weeping forsythia 115g, the membrane of a chicken's gizzard 80g, madder 80g, oldenlandia diffusa 280g, Radix Astragali 280g, the bighead atractylodes rhizome 115g, auxiliary material：Appropriate starch.

Embodiment 2：

A kind of pill medicine for being used to treat lung cancer, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown：

It is cutworm 230g, Sculellaria barbata 310g, Dysosma versipellis 130g, little groundcherry herb or fruit 480g, black nightshade 430g, sealwort 420g, levisticum 90g, ripe Ground 480g, medical stone 480g, indigo naturalis 31g, rhizoma imperatae 310g, Fructus Aurantii 90g, lophatherum gracile 90g, radix glehniae 90g, barrenwort 140g, Coix seed 310g, tuber of dwarf lilyturf 130g, capsule of weeping forsythia 130g, the membrane of a chicken's gizzard 90g, madder 90g, oldenlandia diffusa 310g, Radix Astragali 310g, the bighead atractylodes rhizome 130g, auxiliary material：Appropriate starch.

Embodiment 3：

A kind of pill medicine for being used to treat lung cancer, it is characterised in that each component and its mass parts ratio of the medicine are as follows It is shown：

It is cutworm 260g, Sculellaria barbata 350g, Dysosma versipellis 150g, little groundcherry herb or fruit 550g, black nightshade 500g, sealwort 500g, levisticum 100g, ripe Ground 550g, medical stone 550g, indigo naturalis 35g, rhizoma imperatae 350g, Fructus Aurantii 100g, lophatherum gracile 100g, radix glehniae 100g, barrenwort 160g, coix seed 350g, tuber of dwarf lilyturf 150g, capsule of weeping forsythia 150g, the membrane of a chicken's gizzard 100g, madder 100g, oldenlandia diffusa 350g, the Radix Astragali 350g, bighead atractylodes rhizome 150g, auxiliary material：Appropriate starch.

Model case

Through clinical conditions patients with lung cancer totally 500, the age is 350 of more than 67 years old, and only 150 are less than 67 years old. 260 that sb.'s illness took a favorable turn in 500 patients, effective 90, invalid 150.Total effective rate is up to 70%.

Claims (3)

1. a kind of pill medicine for being used to treat lung cancer, it is characterised in that each component and its mass parts of the medicine are such as Shown in lower：

150~260g of cutworm, 150~350g of Sculellaria barbata, 50~150g of Dysosma versipellis, 250~550g of little groundcherry herb or fruit, black nightshade 150~ 500g, 250~500g of sealwort, 30~100g of levisticum, 200~550g of cultivated land, 200~550g of medical stone, 15~35g of indigo naturalis, 90~350g of rhizoma imperatae, 30~100g of Fructus Aurantii, 60~100g of lophatherum gracile, 50~100g of radix glehniae, 50~160g of barrenwort, Job's tears 90~350g of benevolence, 60~150g of the tuber of dwarf lilyturf, 60~150g of the capsule of weeping forsythia, 30~100g of the membrane of a chicken's gizzard, 60~100g of madder, oldenlandia diffusa 150~350g, 90~350g of the Radix Astragali, 60~150g of the bighead atractylodes rhizome, auxiliary material：Appropriate starch.

2. the pill medicine according to claim 1 for being used to treat lung cancer, it is characterised in that each component of the medicine And its mass parts are than as follows：

180~230g of cutworm, 180~310g of Sculellaria barbata, 58~130g of Dysosma versipellis, 280~480g of little groundcherry herb or fruit, black nightshade 180~ It is 430g, 280~420g of sealwort, 38~90g of levisticum, 260~480g of cultivated land, 260~480g of medical stone, 18~31g of indigo naturalis, white 100~310g of lalang grass rhizome, 38~90g of Fructus Aurantii, 70~90g of lophatherum gracile, 58~90g of radix glehniae, 58~140g of barrenwort, coix seed 100~310g, 70~130g of the tuber of dwarf lilyturf, 70~130g of the capsule of weeping forsythia, 38~90g of the membrane of a chicken's gizzard, 70~90g of madder, oldenlandia diffusa 180~ 310g, 100~310g of the Radix Astragali, 70~130g of the bighead atractylodes rhizome, auxiliary material：Appropriate starch.

3. being used for according to claim 1 to 2 treats the pill medicine of lung cancer, it is characterised in that the medicine it is each Component and its mass parts are than as follows：

It is cutworm 200g, Sculellaria barbata 280g, Dysosma versipellis 115g, little groundcherry herb or fruit 420g, black nightshade 380g, sealwort 380g, levisticum 80g, ripe Ground 420g, medical stone 420g, indigo naturalis 28g, rhizoma imperatae 280g, Fructus Aurantii 80g, lophatherum gracile 80g, radix glehniae 80g, barrenwort 120g, Coix seed 280g, tuber of dwarf lilyturf 115g, capsule of weeping forsythia 115g, the membrane of a chicken's gizzard 80g, madder 80g, oldenlandia diffusa 280g, Radix Astragali 280g, the bighead atractylodes rhizome 115g, auxiliary material：Appropriate starch.