CN107441368A - It is a kind of that there is integration of drinking and medicinal herbs composition for improving immunity and preparation method thereof - Google Patents
It is a kind of that there is integration of drinking and medicinal herbs composition for improving immunity and preparation method thereof Download PDFInfo
- Publication number
- CN107441368A CN107441368A CN201710604181.2A CN201710604181A CN107441368A CN 107441368 A CN107441368 A CN 107441368A CN 201710604181 A CN201710604181 A CN 201710604181A CN 107441368 A CN107441368 A CN 107441368A
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- Prior art keywords
- parts
- ginseng
- semen sesami
- mulberries
- sesami nigrum
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/88—Liliopsida (monocotyledons)
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Abstract
The invention discloses a kind of integration of drinking and medicinal herbs composition for having and improving immunity and preparation method thereof.The present composition is made up of the integration of drinking and medicinal herbs such as wheat seeding, ginseng, arillus longan, mulberries, Semen sesami nigrum, sealwort medicinal material and FOS, galactooligosaccharide, play the integrally-regulated advantage of herbal mixture, has the immunity function that increases significantly, experiment confirms that the toes swelling thickness of normal mouse can be reduced, improves NK cytoactives, serum hemolysin, antibody-producting cell quantity, carbonic clearance phagocytic index and macrophage and swallow chicken red blood cell ability.
Description
Technical field
It is more particularly to a kind of with the composition for improving immunity and its specific the invention belongs to field of health care food
Preparation method.
Background technology
Modern civilization brings material enjoyment to the mankind, fundamentally changes the mankind original life style and habit, together
When also carried out substantial amounts of negative effect to mankind's health care belt.With expanding economy, the discharge of modern industry large quantity of exhaust gas causes ground
The destruction of ball atmosphere, global warming, harmful substance excessive emissions, make air, soil, pollution of waterhead.The life of modernization
Product are applied flexibly, such as furniture, interior decoration, art work enter human body entrainment of the harmful carcinogen of formaldehyde by respiratory tract, invade
Lose the health of the mankind.And the life style of contemporary most people is unhealthy, eats and drinks immoderately, and lacks exercise, various generations are caused
Thank to disorder, vivotoxin excretion is obstructed, and above mentioned problem all seriously annoyings the health of the mankind.
The immunologic function for improving body at present typically uses the treatment method of doctor trained in Western medicine, and doctor trained in Western medicine immunology in disease prevention and cure and is controlled
Application prospect in terms for the treatment of allows of no optimist, and cures the symptoms, not the disease.The advantages that Chinese medicine is natural with it in recent years, and toxic side effect is few is increasingly
Cause the concern of people.Chinese medicine is the important component of the traditional Chinese medical science, is coordinating body whole machine balancing, enhancing body resistance against diseases side
Face has unique curative effect.Modern scientific research proves that kind more than 200 has the Chinese medicine of righting or eliminating evil effect, there is good exempt from
Epidemic disease adjustment effect, and have good therapeutic action to many chronic, refractory diseases.In the treatment of many immune correlated diseases
In, acute stage or active stage, are aided with treatment by Chinese herbs, and the paracmasis based on Chinese medical discrimination, treatment by Chinese herbs, tends to receive preferably
Clinical efficacy.
The mankind will possess strong physique, could resist the wound that various virus, bacterium and harmful substances are brought to body
Evil, so we will strengthen autoimmunity and the natural curability to various diseases.
There is the Chinese medicine composition for improving immunity and its specific preparation method the present invention is to provide a kind of.
The content of the invention
There is the Chinese medicine composition for improving immunity and its specific preparation it is an object of the invention to provide a kind of
Method, said composition are made from the following raw materials in parts by weight：
Wheat seeding 25-35 parts, ginseng 3-7 parts, arillus longan 3-7 parts, mulberries 8-12 parts, Semen sesami nigrum 8-12 parts, sealwort 8-12 parts,
FOS 13-17 parts, galactooligosaccharide 13-17 parts.
The weight part ratio of the raw material of the present composition is preferably：
25 parts of wheat seeding, 3 parts of ginseng, 3 parts of arillus longan, 8 parts of mulberries, 8 parts of Semen sesami nigrum, 8 parts of sealwort, 13 parts of FOS are low
Poly- 13 parts of galactolipin.
The weight part ratio of the raw material of the present composition is also preferably：
27 parts of wheat seeding, 4 parts of ginseng, 4 parts of arillus longan, 9 parts of mulberries, 9 parts of Semen sesami nigrum, 9 parts of sealwort, 14 parts of FOS are low
Poly- 14 parts of galactolipin.
The weight part ratio of the raw material of the present composition is also preferably：
30 parts of wheat seeding, 5 parts of ginseng, 5 parts of arillus longan, 10 parts of mulberries, 10 parts of Semen sesami nigrum, 10 parts of sealwort, 15 parts of FOS,
15 parts of galactooligosaccharide.
The weight part ratio of the raw material of the present composition is also preferably：
33 parts of wheat seeding, 6 parts of ginseng, 6 parts of arillus longan, 11 parts of mulberries, 11 parts of Semen sesami nigrum, 11 parts of sealwort, 16 parts of FOS,
16 parts of galactooligosaccharide.
The weight part ratio of the raw material of the present composition is also preferably：
35 parts of wheat seeding, 7 parts of ginseng, 7 parts of arillus longan, 12 parts of mulberries, 12 parts of Semen sesami nigrum, 12 parts of sealwort, 17 parts of FOS,
17 parts of galactooligosaccharide.
The present composition is mainly by the integration of drinking and medicinal herbs Chinese medicine group such as wheat seeding, ginseng, arillus longan, mulberries, Semen sesami nigrum, sealwort
Into various traditional Chinese medicine ingredients merge into each other and play synergy, heighten the effect of a treatment, and have good enhancing immunity function.
Wheat seeding：It is sweet, flat, returns spleen, stomach, there is the effect of promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite, delaactation dissipate-swelling, modern study
Show, there is wheat seeding aid digestion, rush sex hormone secretion, regulation prolactin(PRL, regulation gut flora, anti-platelet aggregation and liver to protect
The effect such as shield.Different wheat seeding oligosaccharide in wheat seeding can play a part of adjusting bifidobacterium growth in vivo and in vitro, to exempting from
Epidemic disease function has certain humidification.
Ginseng：Sweet, warm-natured, slight bitter,《Sheng Nong's herbal classic》In be listed in top grade, for conventional strengthening by means of tonics medicine, tool
Reinforce the spleen to benefit the lung, promote the production of body fluid to quench thirst, tranquilize the mind and promote the intelligence, reinforce vital energy, veins takes off admittedly the effect of.Modern study shows the increasing that ginseng has
Strong memory, improve immunity, improve cardiovascular, anti-aging and the multiple pharmacological effect such as antitumor.Many experiments have proven to
Ginseng can strengthen body's immunity, ginsenoside and panaxan has stimulation to make to the phagocytic function of intact animal endothelial system
With anti-infection ability can be significantly improved.Ginsenoside can not only improve reaction of the mouse bone-marrow-derived lymphocyte to corresponding mitogen
Property, moreover it is possible to immunologic function caused by radioresistance and cold-wate swimming is declined.
Arillus longan：Also known as longan, property is sweet, warm, can tonifying heart and spleen, nourishing blood and tranquilization, for treating insufficiency of vital energy and blood, palpitaition is seized with terror
It is sad, forgetful insomnia, the disease such as blood deficiency chlorosis.Modern study show arillus longan main component be longan polysaccharide, lipid and soaping agents into
Point, there is anti-aging, strengthen immunity, antitumor, regulation endocrine etc..Experiment proves that arillus longan can make mouse
The increase of the T cell quantity of thymus gland and lymph node, illustrates that it has the function that strengthen immunity.
Mulberries：It is sweet sour, cold in nature, the thoughts of returning home, liver and kidney channel, there is liver-kidney tonifying, nourishes blood and promotes the production of body fluid, relax bowel, it is existing
Show for Nutritional studies, mulberries contain nutriment necessary to a variety of human bodies, as essential amino acid, vitamin, calcium,
The mineral matters such as iron, zinc, selenium and resveratrol, polysaccharide and flavones isoreactivity composition.Existing many experiments prove mulberries to spleen
There is effect of gain, the growth of red blood cell can be promoted, there is strengthen immunity, hypoglycemic and anti-aging.
Semen sesami nigrum：For the traditional nourishing liver and kidney class Chinese medicine in China, medicine-food two-purpose, available for caused by treatment liver kidney asthenia of essence and blood
Dizziness, poliosis, alopecia, soreness and weakness of waist and knees, limbs fatigue, the illness such as dry constipation of intestines.It contains abundant lipid, such as oil
Acid, linoleic acid, palmitic acid, stearic acid, arachidic acid etc., additionally containing abundant proteins,vitamins,and minerals, to body
Immunologic function has certain humidification.
Sealwort：Its is sweet, mild-natured, has tonifying spleen moistening lung, the function of supplementing qi and nourishing yin, and the traditional Chinese medical science is usually used in controlling the lung-dryness syndrome due to yin deficiency, kidney
Empty early ageing and weakness of the spleen and the stomach all diseases.Modern pharmacological research proves that its active ingredient is mainly Siberian solomonseal rhizome polysaccharide and steroid saponin, has
The effect such as immunity, hypoglycemic, reducing blood lipid, antibacterial, antiviral, antitumor is improved, in terms of new drug and exploitation health products is developed
With broad development prospect.Having tested proves that sealwort can significantly improve the hemopoietic function of bone marrow of ring phosphorus phthalein amine induced mice, makes
Leucocyte and red blood cell number increase, strengthen immunologic function.
FOS and galactooligosaccharide can not directly be digested and assimilated by human body, but can be absorbed by enteric bacteria, tool
There is promotion proliferation of probiotics, improve lipid-metabolism and reduce the effect such as constipation, and calorific value is low, will not cause obesity.Oligosaccharide
Promote the propagation of beneficial bacteria of intestinal tract, profitable strain can be made to be taken advantage in enteron aisle, suppress the growth of harmful bacteria, reduce Toxic
The formation of matter, there is protective effect to intestinal mucosa cells and liver, so as to prevent the generation of lesion intestinal cancer, strengthen immunity of organisms.
The present composition comprises the steps of：
(1) Chinese medicine is weighed according to bulk drug part by weight, cleaned；
(2) wheat seeding, arillus longan, mulberries and sealwort are placed in Chinese medicament extracting device, add the 5-6 times of water measured, heating, micro-boiling
In the case of extract 0.5-1.5h, extract 2-3 time, mix the extract solution of gained every time, filtration, be concentrated under reduced pressure at 50 DEG C relatively
Density is 1-1.3 thick paste, is dried under reduced pressure and is ground into fine powder；
(3) it will be crushed after Semen sesami nigrum parch with medicinal herb grinder, collect fine powder (crossing 300 mesh)；
(4) ginseng is crushed with medicinal herb grinder, collects fine powder (crossing 300 mesh)；
(5) fine powder obtained by step (2) is mixed with Semen sesami nigrum fine powder, ginseng fine powder, FOS, galactooligosaccharide
It is even, produce.
The formulation of the present composition is oral powder, tablet, capsule or granule.
Embodiment
With reference to embodiment, technical scheme is further illustrated.
Raw material used in following examples is purchased from the peaceful medicinal material market in Guangzhou.
Embodiment 1
Prescription：25 parts of wheat seeding, 3 parts of ginseng, 3 parts of arillus longan, 8 parts of mulberries, 8 parts of Semen sesami nigrum, 8 parts of sealwort, FOS 13
Part, 13 parts of galactooligosaccharide.
Preparation method：
(1) Chinese medicine is weighed according to bulk drug part by weight, cleaned；
(2) wheat seeding, arillus longan, mulberries and sealwort are placed in Chinese medicament extracting device, add the 5-6 times of water measured, heating, micro-boiling
In the case of extract 0.5-1.5h, extract 2-3 time, mix the extract solution of gained every time, filtration, be concentrated under reduced pressure at 50 DEG C relatively
Density is 1-1.3 thick paste, is dried under reduced pressure and is ground into fine powder；
(3) it will be crushed after Semen sesami nigrum parch with medicinal herb grinder, collect fine powder (crossing 300 mesh)；
(4) ginseng is crushed with medicinal herb grinder, collects fine powder (crossing 300 mesh)；
(5) fine powder obtained by step (2) is mixed with Semen sesami nigrum fine powder, ginseng fine powder, FOS, galactooligosaccharide
It is even, produce.
Embodiment 2
Prescription：27 parts of wheat seeding, 4 parts of ginseng, 4 parts of arillus longan, 9 parts of mulberries, 9 parts of Semen sesami nigrum, 9 parts of sealwort, FOS 14
Part, 14 parts of galactooligosaccharide.
Preparation method：
(1) Chinese medicine is weighed according to bulk drug part by weight, cleaned；
(2) wheat seeding, arillus longan, mulberries and sealwort are placed in Chinese medicament extracting device, add the 5-6 times of water measured, heating, micro-boiling
In the case of extract 0.5-1.5h, extract 2-3 time, mix the extract solution of gained every time, filtration, be concentrated under reduced pressure at 50 DEG C relatively
Density is 1-1.3 thick paste, is dried under reduced pressure and is ground into fine powder；
(3) it will be crushed after Semen sesami nigrum parch with medicinal herb grinder, collect fine powder (crossing 300 mesh)；
(4) ginseng is crushed with medicinal herb grinder, collects fine powder (crossing 300 mesh)；
(5) fine powder obtained by step (2) is mixed with Semen sesami nigrum fine powder, ginseng fine powder, FOS, galactooligosaccharide
It is even, produce.
Embodiment 3
Prescription：30 parts of wheat seeding, 5 parts of ginseng, 5 parts of arillus longan, 10 parts of mulberries, 10 parts of Semen sesami nigrum, 10 parts of sealwort, FOS
15 parts, 15 parts of galactooligosaccharide.
Preparation method：
(1) Chinese medicine is weighed according to bulk drug part by weight, cleaned；
(2) wheat seeding, arillus longan, mulberries and sealwort are placed in Chinese medicament extracting device, add the 5-6 times of water measured, heating, micro-boiling
In the case of extract 0.5-1.5h, extract 2-3 time, mix the extract solution of gained every time, filtration, be concentrated under reduced pressure at 50 DEG C relatively
Density is 1-1.3 thick paste, is dried under reduced pressure and is ground into fine powder；
(3) it will be crushed after Semen sesami nigrum parch with medicinal herb grinder, collect fine powder (crossing 300 mesh)；
(4) ginseng is crushed with medicinal herb grinder, collects fine powder (crossing 300 mesh)；
(5) fine powder obtained by step (2) is mixed with Semen sesami nigrum fine powder, ginseng fine powder, FOS, galactooligosaccharide
It is even, produce.
Embodiment 4
Prescription：33 parts of wheat seeding, 6 parts of ginseng, 6 parts of arillus longan, 11 parts of mulberries, 11 parts of Semen sesami nigrum, 11 parts of sealwort, FOS
16 parts, 16 parts of galactooligosaccharide.
Preparation method：
(1) Chinese medicine is weighed according to bulk drug part by weight, cleaned；
(2) wheat seeding, arillus longan, mulberries and sealwort are placed in Chinese medicament extracting device, add the 5-6 times of water measured, heating, micro-boiling
In the case of extract 0.5-1.5h, extract 2-3 time, mix the extract solution of gained every time, filtration, be concentrated under reduced pressure at 50 DEG C relatively
Density is 1-1.3 thick paste, is dried under reduced pressure and is ground into fine powder；
(3) it will be crushed after Semen sesami nigrum parch with medicinal herb grinder, collect fine powder (crossing 300 mesh)；
(4) ginseng is crushed with medicinal herb grinder, collects fine powder (crossing 300 mesh)；
(5) fine powder obtained by step (2) is mixed with Semen sesami nigrum fine powder, ginseng fine powder, FOS, galactooligosaccharide
It is even, produce.
Embodiment 5
Prescription：35 parts of wheat seeding, 7 parts of ginseng, 7 parts of arillus longan, 12 parts of mulberries, 12 parts of Semen sesami nigrum, 12 parts of sealwort, FOS
17 parts, 17 parts of galactooligosaccharide.
Preparation method：
(1) Chinese medicine is weighed according to bulk drug part by weight, cleaned；
(2) wheat seeding, arillus longan, mulberries and sealwort are placed in Chinese medicament extracting device, add the 5-6 times of water measured, heating, micro-boiling
In the case of extract 0.5-1.5h, extract 2-3 time, mix the extract solution of gained every time, filtration, be concentrated under reduced pressure at 50 DEG C relatively
Density is 1-1.3 thick paste, is dried under reduced pressure and is ground into fine powder；
(3) it will be crushed after Semen sesami nigrum parch with medicinal herb grinder, collect fine powder (crossing 300 mesh)；
(4) ginseng is crushed with medicinal herb grinder, collects fine powder (crossing 300 mesh)；
(5) fine powder obtained by step (2) is mixed with Semen sesami nigrum fine powder, ginseng fine powder, FOS, galactooligosaccharide
It is even, produce.
In order to confirm that the present composition has the function that to improve immunity, the fine powder as made from the method for embodiment 3, carry out
Animal experiment study once：
1 experiment material
1.1 medicines and reagent composition extraction medicinal extract, 1640 complete mediums；NaHCO3；Glutamine；Penicillin；Chain
Mycin；Newborn calf serum；Hanks working solutions (pH7.2~7.4)；PMS；Oxidized coenzyme I；Lactic acid
Lithium；Thiazolyl blue (MTT)；Canavalin (ConA)；P-Iodonitrotetrazolium violet；2%NP40；0.2mol/L hydrochloric acid-Tris buffer solutions；
YAC-1 cells；Potassium cyanide；The potassium ferricyanide；Guinea pig serum；Sheep red blood cell (SRBC)；India ink；Yellow Jackets.
1.2 animal Kunming kind female secondary mouses, 18~22g of body weight, are provided by Guangdong Province's Experimental Animal Center.
The ultraviolet specrophotometer of 1.3 instrument 752；NU-2500E type CO2 incubators；Superclean bench；AE100 electronics day
It is flat；DT500 electronic balances；TDL-5 centrifuges；KA-1000 type desk centrifuges；Biomicroscope；JY92-II type ultrasonic waves are thin
Born of the same parents' pulverizer；Micrometer caliper (0.01mm)；YXQG01 type steam sterilizing pans；Bacterial filter；The board-like ELIASAs of CF-5000；Electricity
Heat three uses water tank；24 hole flat-bottomed plates；96 hole U-shaped culture plates；96 hole flat bottom assay plates；Stopwatch.
2 experimental methods
2.1 pharmacological experimental methods (1) delayed allergy (DTH)-toes swelling Thickness Method；(2) T lymphocytes increase
Growing functional examination-ConA stimulates leaching to turn color reaction method (mtt assay)；(3) measure (lactic dehydrogenase enzyme process) of NK cytoactives；
(4) measure of antibody-producting cell；(5) measure (half hemolytic value determination method) of serum hemolysin；(6) survey of carbonic clearance index
It is fixed：Carbonic clearance is tested；(7) Turnover of Mouse Peritoneal Macrophages phagocytosis chicken red blood cell experiment.
2.2 statistical procedures experimental results carry out statistical procedures using SPSS13.0 statistical softwares.Data use mean
± standard deviationRepresent, using variance analysis, inspection level α=0.05.
3 experimental results
Influence of 3.1 compositions to normal mouse weight, thymus gland/body weight, spleen/body weight, is shown in Table 1.
Influence of the table 1 to normal mouse immune organ weight
From table 1, after gavage 28d, compared with control group, each dosage group body weight, thymus gland/body weight, spleen/weight differences
Meaning that there are no significant (P ＞ 0.05).
Influence of 3.2 compositions to normal mouse delayed allergy, is shown in Table 2.
Influence of the table 2 to normal mouse toes swelling thickness
Compared with control group,*P ＜ 0.01.
From table 2, after gavage normal mouse test medicine 28d, compared with control group, the toes of basic, normal, high dosage swell
22.3% (P ＜ 0.01), 33.3% (P ＜ 0.01), 40.2% (P ＜ 0.01) is respectively increased in swollen thickness.
Influence of 3.3 compositions to normal mice spleen lymphocytes proliferation ability, is shown in Table 3.
Influence of the table 3 to normal mouse spleen lymphocyte ConA multiplication capacities
From table 3, after gavage normal mouse test medicine 8d, compared with control group, low, high dose group be respectively increased through
The spleen lymphocyte proliferation ability 31.1% (P ＞ 0.05) of ConA inductions, 5.1% (P ＞ 0.05), 3.9% (P ＞ 0.05).
Influence of 3.4 compositions to normal NK cells in mice activity, is shown in Table 4.
Influence of the table 4 to normal NK cells in mice activity
Compared with control group,*P ＜ 0.05.
From table 4, after gavage normal mouse test medicine 28d, compared with control group, Chinese medicine composition low dose group
NK cytoactives improve 62.2% (P ＜ 0.05).
Influence of 3.5 compositions to normal mouse antibodies cellulation, is shown in Table 5.
Influence of the table 5 to normal mouse PEC
Compared with control group,*P ＜ 0.05.
From table 5, after gavage normal mouse test medicine 28d, compared with control group, the PFC of low dose group is improved
5.3% (P ＜ 0.05).
Influence of 3.6 compositions to Normal Mouse Serum hemolysin level, is shown in Table 6.
The influence horizontal to Normal Mouse Serum HC50 of table 6
Compared with control group,*P ＜ 0.05.
From table 6, after gavage normal mouse test medicine 28d, compared with control group, the HC50 of low dose group is improved
17.1% (P ＜ 0.05).
Influence of 3.7 compositions to normal mouse carbonic clearance ability, is shown in Table 7.
Influence of the table 7 to normal mouse carbonic clearance
Compared with control group,*P ＜ 0.05.
From table 7, after gavage normal mouse test medicine 28d, compared with control group, the carbonic clearance index of low dose group
Improve 15.9% (P ＜ 0.05).
3.8 compositions are shown in Table 8 to Turnover of Mouse Peritoneal Macrophages phagocytosis chicken red blood cell experiment (half intracorporal method).
Influence of the table 8 to Turnover of Mouse Peritoneal Macrophages phagocytic activity
Compared with control group,*P ＜ 0.05.
From table 8, the high, medium and low dosage group phagocytic rate of composition, phagocytic index and Normal group comparing difference have aobvious
Work property meaning (P ＜ 0.05).Illustrate test medicine in 6.5mg/kg/d, 13.0mg/kg/d, 26.0mg/kg/d (equivalent to human body
Recommend take the photograph people amount 10 times, 20 times, 40 times) dosage when, be respectively provided with enhancing Turnover of Mouse Peritoneal Macrophages phagocytic activity effect.
4 experiment conclusions
Originally test result indicates that, the composition of orally administration low dosage, compared with control group, the foot of normal mouse can be reduced
Toe swelling thickness, improve NK cytoactives, serum hemolysin, antibody-producting cell quantity, carbonic clearance phagocytic index and huge
Phagocyte swallows chicken red blood cell ability, illustrates that said composition has the immunity that is significantly improved, and its effect and dosage
There are much relations.
Above-described embodiment is the preferable embodiment of the present invention, is served only for help and understands the present invention, embodiment party of the invention
Formula is simultaneously not restricted to the described embodiments, other it is any without departing from the present invention Spirit Essences and principle under made change, repair
Decorations, substitute, combination or simplified, be regarded as equivalent substitute mode, all should belong within the scope of the present invention.
Claims (9)
1. a kind of have composition for improving immunity and preparation method thereof, it is characterised in that by the raw material of following parts by weight
It is made：
Wheat seeding 25-35 parts, ginseng 3-7 parts, arillus longan 3-7 parts, mulberries 8-12 parts, Semen sesami nigrum 8-12 parts, sealwort 8-12 parts are oligomeric
Fructose 13-17 parts, galactooligosaccharide 13-17 parts.
2. application according to claim 1, it is characterised in that be made up of the raw material of following parts by weight：
25 parts of wheat seeding, 3 parts of ginseng, 3 parts of arillus longan, 8 parts of mulberries, 8 parts of Semen sesami nigrum, 8 parts of sealwort, 13 parts of FOS, oligomeric half
13 parts of lactose.
3. application according to claim 1, it is characterised in that be made up of the raw material of following parts by weight：
27 parts of wheat seeding, 4 parts of ginseng, 4 parts of arillus longan, 9 parts of mulberries, 9 parts of Semen sesami nigrum, 9 parts of sealwort, 14 parts of FOS, oligomeric half
14 parts of lactose.
4. application according to claim 1, it is characterised in that be made up of the raw material of following parts by weight：
30 parts of wheat seeding, 5 parts of ginseng, 5 parts of arillus longan, 10 parts of mulberries, 10 parts of Semen sesami nigrum, 10 parts of sealwort, 15 parts of FOS are oligomeric
15 parts of galactolipin.
5. application according to claim 1, it is characterised in that be made up of the raw material of following parts by weight：
33 parts of wheat seeding, 6 parts of ginseng, 6 parts of arillus longan, 11 parts of mulberries, 11 parts of Semen sesami nigrum, 11 parts of sealwort, 16 parts of FOS are oligomeric
16 parts of galactolipin.
6. application according to claim 1, it is characterised in that be made up of the raw material of following parts by weight：
35 parts of wheat seeding, 7 parts of ginseng, 7 parts of arillus longan, 12 parts of mulberries, 12 parts of Semen sesami nigrum, 12 parts of sealwort, 17 parts of FOS are oligomeric
17 parts of galactolipin.
7. according to the application described in claim any one of 1-6, it is characterised in that the composition comprises the steps of：
(1) Chinese medicine is weighed according to bulk drug part by weight, cleaned；
(2) wheat seeding, arillus longan, mulberries and sealwort are placed in Chinese medicament extracting device, add the 5-6 times of water measured, heating, micro-boiling situation
Lower extraction 0.5-1.5h, extract 2-3 times, mix the extract solution of gained every time, filtration, be concentrated under reduced pressure into the relative density at 50 DEG C
For 1-1.3 thick paste, it is dried under reduced pressure and is ground into fine powder；
(3) it will be crushed after Semen sesami nigrum parch with medicinal herb grinder, collect fine powder (crossing 300 mesh)；
(4) ginseng is crushed with medicinal herb grinder, collects fine powder (crossing 300 mesh)；
(5) fine powder obtained by step (2) is well mixed with Semen sesami nigrum fine powder, ginseng fine powder, FOS, galactooligosaccharide, i.e.,
.
8. composition according to claim 7, it is characterised in that：The formulation of composition is oral powder or preparation.
9. composition according to claim 8, it is characterised in that：Oral formulations are selected from tablet, capsule, granule.
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| CN109170865A (en) * | 2018-09-30 | 2019-01-11 | 湖北天夏生物工程有限公司 | A kind of health care product and preparation method thereof adjusting immunity |
| CN109430721A (en) * | 2018-10-17 | 2019-03-08 | 广州市好孝心医疗器械有限公司 | A kind of wheat embryo composition and preparation method thereof with hypoglycemic effect |
| CN110437963A (en) * | 2019-07-26 | 2019-11-12 | 珠海宝德润生健康科技有限公司 | A kind of beverage and preparation method thereof containing ginseng |
| CN114796393A (en) * | 2022-06-16 | 2022-07-29 | 张瑞芳 | Medicinal and edible decoction special for blackening white hair and regenerating alopecia and preparation method thereof |
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| CN114796393A (en) * | 2022-06-16 | 2022-07-29 | 张瑞芳 | Medicinal and edible decoction special for blackening white hair and regenerating alopecia and preparation method thereof |
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