CN107441354A - Application of the Chinese medicine composition in reducing blood lipid or anti-trioxypurine medicine and health products are prepared - Google Patents
Application of the Chinese medicine composition in reducing blood lipid or anti-trioxypurine medicine and health products are prepared Download PDFInfo
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- CN107441354A CN107441354A CN201710381586.4A CN201710381586A CN107441354A CN 107441354 A CN107441354 A CN 107441354A CN 201710381586 A CN201710381586 A CN 201710381586A CN 107441354 A CN107441354 A CN 107441354A
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- chrysanthemum
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- trioxypurine
- reducing blood
- blood lipid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
- A23F3/00—Tea; Tea substitutes; Preparations thereof
- A23F3/34—Tea substitutes, e.g. matè; Extracts or infusions thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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Abstract
The present invention relates to application of the Chinese medicine composition in reducing blood lipid or anti-trioxypurine medicine is prepared, Chinese medicine composition fraction by weight calculates, including following components：20 parts of folium cortex eucommiae, 0.05 2 parts of rhizoma Gastrodiae and chrysanthemum or 1 10 parts of chrysanthemum indicum.Preferably, Chinese medicine composition fraction by weight calculates, including following components：20 parts of folium cortex eucommiae, 0.1 1 parts of rhizoma Gastrodiae and chrysanthemum or 15 parts of chrysanthemum indicum.Chrysanthemum is Bo chrysanthemum, chu chrysanthemum, tribute chrysanthemum and Hang Juzhong one or more of mixtures.Treating or preventing in high fat of blood or antihyperuricemic disease drug also includes pharmaceutically acceptable pharmaceutic adjuvant.The chemical synthetic drug that the present invention can effectively solve existing treatment reducing blood lipid and anti-trioxypurine destroys body metabolic mechanism in itself, has side effect to body, takes frequently and Chinese patent medicine formula is complicated, and compatibility is bad, the problem of need to often taking medicine.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly, to Chinese medicine composition prepare reducing blood lipid or anti-trioxypurine medicine and
Application in health products.
Background technology
With socio-economic development and the huge change of national life mode, China's dyslipidemia and hyperuricemia are ill
Rate is lifted continuously and healthily.
Treatment high fat of blood and the medicine of hyperuricemia include chemical synthetic drug and Chinese patent drug, and current various medicines are to height
Blood fat and the Results of hyperuricemia also have certain limitation more.Currently used reducing blood lipid chemical synthetic drug has：He
Spit of fland class, fibrates, nicotinic acid class, cholic acid chelating agent etc..These medicines exist action time it is short need to medication, side effect daily it is big etc.
Problem.And there is the problem of DeGrain in reducing blood lipid Chinese patent drug mostly.
Currently used gout chemical synthetic drug mainly has：Nonsteroidal anti-inflammatory, colchicin, glucocorticoid.
Anti-trioxypurine, which mainly has, suppresses uric acid generation medicine and uricosureic agent.The preventing and treating of gout is needed according to individual in different hairs at present
Making the phase uses different medication combined preventing and treatings.Existing drug medication method is complicated, and present clinical medicine limitation is big and malicious
Side effect is more serious.
Also there are many deficiencies in existing Chinese patent drug, e.g., strong to drug dependence to reducing blood lipid and the preventing and treating of anti-trioxypurine, greatly
It must often take, can not be discontinued more, effect also need to be improved.In addition, during multi-medicament compatible use, complicated formula
In, composition is complicated, and Chinese medicine quality control is difficult, and Part of Chinese Medicinal also contains some insalubrious drug ingedients, president
Phase takes and is enriched with, and damages health.
Therefore, be badly in need of at present a kind of positive effect, safety, convenient means intervene the hair of high fat of blood and high lithemia blood fat
Exhibition, the present invention is preferable solution to the problems described above.
The content of the invention
The problem to be solved in the present invention is to provide Chinese medicine composition in reducing blood lipid or anti-trioxypurine medicine and health products are prepared
Application, the chemical synthetic drug for solving existing treatment reducing blood lipid and anti-trioxypurine destroys body metabolic mechanism in itself, to body
There is side effect, take frequent and Chinese patent medicine formula complexity, compatibility is bad, the problem of need to often taking medicine.
In order to solve the above technical problems, the technical solution adopted by the present invention is：Chinese medicine composition is preparing reducing blood lipid or drop
Application in uric acid medicine, Chinese medicine composition fraction by weight calculates, including following components：20 parts of folium cortex eucommiae, rhizoma Gastrodiae 0.05-2
Part and chrysanthemum or chrysanthemum indicum 1-10 parts.
In technical scheme, it is preferred that Chinese medicine composition fraction by weight calculates, including following components：Folium cortex eucommiae 20 part, day
Numb 0.1-1 parts and chrysanthemum or chrysanthemum indicum 1-5 parts.
In technical scheme, it is preferred that chrysanthemum is Bo chrysanthemum, chu chrysanthemum, tribute chrysanthemum and Hang Juzhong one or more of mixtures.
In technical scheme, it is preferred that also include pharmaceutically acceptable pharmaceutic adjuvant in reducing blood lipid or anti-trioxypurine medicine.
In technical scheme, it is preferred that the formulation of reducing blood lipid or anti-trioxypurine medicine is oral liquid, pill, granule, piece
Agent, electuary, syrup, powder, freeze-dried powder or capsule.
It is a further object of the present invention to provide application of the Chinese medicine composition in reducing blood lipid or anti-trioxypurine health products are prepared, in
Drug composition fraction by weight calculates, including following components：20 parts of folium cortex eucommiae, rhizoma Gastrodiae 0.05-2 parts and chrysanthemum or chrysanthemum indicum 1-10
Part.
In technical scheme, it is preferred that Chinese medicine composition fraction by weight calculates, including following components：Folium cortex eucommiae 20 part, day
Numb 0.1-1 parts and chrysanthemum or chrysanthemum indicum 1-5 parts.
In technical scheme, it is preferred that chrysanthemum is Bo chrysanthemum, chu chrysanthemum, tribute chrysanthemum and Hang Juzhong one or more of mixtures.
In technical scheme, it is preferred that it is acceptable auxiliary also to include field of health care food in reducing blood lipid or anti-trioxypurine health products
Material.
In technical scheme, it is preferred that reducing blood lipid or anti-trioxypurine health products are oral liquid, capsule, tea-drinking or electuary.
The present invention has the advantages and positive effects of：
1. the herbal composite provided by the invention with reducing blood lipid and anti-trioxypurine effect, composition is simple, and quality is easy
Control.Traditional Chinese medicinal materials assortment is numerous, and the place of production is different, and the quality of most medicinal materials also has suitable relation with manufacture craft, condition.If group
The material category of side is more, it is difficult to ensure that such as one the effect of finished product preparation.This herbal composite only three kinds of materials, raw material
Uniformity is easily controlled, the effect of being easy to ensure this herbal composite.
2. the security of a herbal composite is good.Reducing blood lipid of the prior art and the herbal composite of anti-trioxypurine,
Formula is complicated, when several kinds of Chinese medicinal materials is used for a prescription, it is difficult to control the side effect of some medicinal materials.And a variety of medicinal materials make jointly
Used time, easy restriction or checking relation in five elements cancellation, the effect of influenceing prescription.This herbal composite formula is simple, utilizes rhizoma Gastrodiae, chrysanthemum or chrysanthemum indicum
With folium cortex eucommiae compatibility, the side effect of preparation is admirably avoided.In clinical evaluating drug effect, obvious toxic-side effects are had no.Normal person
Group takes, and has no obvious Blood Lipid, and to body not damaged, the risk of excessive lipid-loweringing is not present in prescription, is urinated in reducing blood lipid and drop
The blood pressure situation that can also improve while sour.
3. it is easy to get in the present invention using folium cortex eucommiae as raw material, raw material, it is easy to process, easily preserve, reduce prescription
Cost.Compared to the bark of eucommia, folium cortex eucommiae abundance, without that can start to pluck when trees grow up to, and can all pluck every year,
Injury to trees is also very limited.Folium cortex eucommiae harvesting, preservation in the present invention is extremely easy, and fresh folium cortex eucommiae only needs to pluck
It is stored in after clean dry at shady and cool dry, without cumbersome, strict processing process.
4. a herbal composite, effect is notable, reducing blood lipid, and anti-trioxypurine is obvious.Folium cortex eucommiae is used alone and prepares Chinese herbal medicine
During preparation, have no that it has reducing blood lipid and anti-trioxypurine effect.Three taste medicinal material property of medicine compatibilities show obvious reducing blood lipid in the present invention,
Anti-trioxypurine acts on.Herbal composite provided by the invention, only takes one, can maintain normal lipid and uric acid for up to one
As long as year.Up to the present, nonresponder is not yet found, reducing blood lipid and anti-trioxypurine effect are good.
5. Chinese medicine preparation or health food made of the herbal composite of the present invention, convenient to take, dose is small, greatly
Facilitate the life and work of patient.This herbal composite dose is small, and every dose of medicinal material amount is：Folium cortex eucommiae 20g, rhizoma Gastrodiae 0.05~
2g, 1~10g of chrysanthemum or chrysanthemum indicum, is easily absorbed by the human body, has no obvious toxic-side effects.
In addition, this herbal composite is employed as defined in health ministry available in the article list of health food
Material, this herbal composite can both develop Chinese medicine, can be used for developing health food, have broad application prospects.
Embodiment
In order to be better understood from the present invention, the present invention is further described with reference to specific embodiment.
Raw materials used or auxiliary material can be bought by market in herbal composite provided by the invention and preparation method thereof.It is former
The specification of material medicinal material meets national standard.
Described customary adjuvant is 2015 editions in following examples《Chinese Pharmacopoeia》In 270 kinds of routines recording it is medicinal auxiliary
Material, similar auxiliary material effect is similar, and function phase is same, and interchangeability is strong, the medicine of the addible identical function of the preparation in each embodiment
May be selected different auxiliary materials with auxiliary material, those skilled in the art according to《Chinese Pharmacopoeia》In record can understand in every kind of preparation
The auxiliary material type and dosage that should be added, therefore specific auxiliary material is no longer pointed out in embodiment.
Embodiment 1
A kind of herbal composite with reducing blood lipid and anti-trioxypurine effect, prescription are formed：Folium cortex eucommiae 20g, chrysanthemum indicum 1g,
Rhizoma Gastrodiae 0.05g.
A kind of Chinese medicine preparation, formulation are tablet, by the above-mentioned herbal composite system with reducing blood lipid and anti-trioxypurine effect
It is standby to form.Preparation method：Rhizoma Gastrodiae is crushed, after crossing 120 mesh sieves, mixed with folium cortex eucommiae and chrysanthemum indicum, adds 10 times of prescription weights
The pure water of amount decocts 2 times, decocts 40min every time.Merge water decoction twice, filtering.Filtrate decompression is concentrated, must be soaked
Cream.Medicinal extract is mixed with customary adjuvant, Chinese medicinal tablet is conventionally prepared.
Embodiment 2
A kind of herbal composite with reducing blood lipid and anti-trioxypurine effect, prescription are formed：Folium cortex eucommiae 20g, Huang Ju 2g, day
Numb 0.1g.
A kind of Chinese medicine preparation, formulation are oral liquid, by the above-mentioned herbal composite with reducing blood lipid and anti-trioxypurine effect
It is prepared.Preparation method：150 mesh sieves are crossed after rhizoma Gastrodiae is crushed, after being well mixed with folium cortex eucommiae and yellow chrysanthemum, use pure water
1000ml, add water to cook 3 times.500ml water is added for the first time, is decocted 45min, is isolated fried liquid；Second of addition 300ml
Water, 30min is decocted, isolates fried liquid；Third time adds 200ml water, decocts 20min, isolates fried liquid.Merging is decocted three times
The fried liquid boiled, filtering, is concentrated into 500ml, directly oral.
Embodiment 3
A kind of herbal composite with reducing blood lipid and anti-trioxypurine effect, prescription are formed：Folium cortex eucommiae 20g, chrysanthemum indicum
2.5g, rhizoma Gastrodiae 0.5g.
A kind of Chinese medicine preparation, formulation are oral formulations, are combined by the above-mentioned Chinese herbal medicine with reducing blood lipid and anti-trioxypurine effect
Thing is prepared.Preparation method：180 mesh sieves are crossed after rhizoma Gastrodiae is crushed, after being well mixed with folium cortex eucommiae and chrysanthemum indicum, use pure water
1000ml, add water to cook 3 times.500ml water is added for the first time, is decocted 45min, is isolated fried liquid；Second of addition 300ml
Water, 30min is decocted, isolates fried liquid；Third time adds 200ml water, decocts 20min, isolates fried liquid.Merging is decocted three times
The fried liquid boiled, is down to normal temperature, and impurity is removed by filter membrane, after being mixed with customary adjuvant, sterilizes, be canned, being sealed to orally make
Agent.
Embodiment 4
A kind of herbal composite with reducing blood lipid and anti-trioxypurine effect, prescription are formed：Folium cortex eucommiae 20g, tribute chrysanthemum 3g, day
Numb 0.2g.
A kind of health food, it is prepared by the above-mentioned herbal composite with reducing blood lipid and anti-trioxypurine effect.
Preparation method：150 mesh sieves are crossed after rhizoma Gastrodiae is crushed, are returned with the ethanol (volume fraction 75%) of 5 times of rhizoma Gastrodiae weight
Stream extraction three times, each 30min, merges extract solution three times.Crushed after folium cortex eucommiae and tribute chrysanthemum are mixed, add 5 times of barks of eucommia
Leaf and the extraction of the alcohol reflux of tribute chrysanthemum gross weight twice, each 30min, merge extract solution twice.Two kinds of extract solutions are mixed
After filter, take filtrate, add with reclaiming ethanol after the water of the weight such as prescription, sterilized after being filtrated to get clarified solution.After sterilizing
Clarified solution be put into freeze drier, freeze-dried powder (weight of water be less than 0.5%) is obtained, after being mixed with the auxiliary material of routine healthcare food
100 mesh sieves are crossed, are packaged into the health food of electuary form.
Embodiment 5
A kind of herbal composite with reducing blood lipid and anti-trioxypurine effect, prescription are formed：Folium cortex eucommiae 20g, chrysanthemum indicum 4g,
Rhizoma Gastrodiae 0.6g,
A kind of Chinese medicine preparation, formulation are pill, by the above-mentioned herbal composite system with reducing blood lipid and anti-trioxypurine effect
It is standby to form.Preparation method：Cross more than 180 mesh after rhizoma Gastrodiae is crushed, mixed with folium cortex eucommiae and chrysanthemum indicum, add 10 times of prescription weights
The decocting of amount is boiled 2 times, decocts 40min every time, is merged water decoction, is filtered to remove impurity, with conventional method, is mixed with customary adjuvant
Close, medicine pill is made.
Embodiment 6
A kind of herbal composite with reducing blood lipid and anti-trioxypurine effect, prescription are formed：Folium cortex eucommiae 20g, Hang Ju 5g, day
Numb 0.3g.
A kind of Chinese medicine preparation, formulation are syrup, by the above-mentioned herbal composite with reducing blood lipid and anti-trioxypurine effect
It is prepared.Preparation method：Rhizoma Gastrodiae is crushed to more than 120 mesh, is mixed with folium cortex eucommiae and Hang Ju, 5 times of prescription weight of addition
Ethanol (volume fraction 95%) refluxing extraction 2 times, 30min is extracted every time, merge extract solution, be filtered to remove impurity, be concentrated under reduced pressure
Obtain medicinal extract.Medicinal extract is mixed with customary adjuvant.With conventional method, syrup is made.
Embodiment 7
A kind of herbal composite with reducing blood lipid and anti-trioxypurine effect, prescription are formed：Folium cortex eucommiae 20g, Bo chrysanthemum 8g, day
Numb 1.0g.
A kind of health food, its type are tea-drinking, by the above-mentioned herbal composite with reducing blood lipid and anti-trioxypurine effect
It is prepared.Preparation method：120 mesh sieves are crossed after rhizoma Gastrodiae is crushed, folium cortex eucommiae and milli chrysanthemum mixture cross 20 mesh sieves after crushing, by two
Added after crushed material mixing after sieving in jacketed pan.Extracted 2 times with the water of 10 times of prescription weight, merge the extract solution of 2 times
After filter, obtain filtrate.The green-tea extract of the weight such as filtrate and prescription is added in blend tank, adds other customary adjuvants
Allocated.Mixture after allotment filters, sterilizes, be filling, sealing to obtain tea-drinking.
Embodiment 8
A kind of herbal composite with reducing blood lipid and anti-trioxypurine effect, prescription are formed：Folium cortex eucommiae 20g, chrysanthemum indicum
10g, rhizoma Gastrodiae 0.3g.
A kind of health food, its type are capsule, are combined by the above-mentioned Chinese herbal medicine with reducing blood lipid and anti-trioxypurine effect
Thing is prepared.Preparation method：120 mesh sieves are crossed after rhizoma Gastrodiae is crushed, folium cortex eucommiae, chrysanthemum indicum cross 20 mesh sieves after crushing respectively, will
Three kinds of crushed materials mixing after sieving, the decocting for adding 10 times of prescription weight are boiled 2 times, decoct 40min every time, merge twice
Water decoction, impurity is filtered to remove, be concentrated under reduced pressure to obtain medicinal extract.Medicinal extract is mixed into use with customary adjuvant, Chinese medicine is made in conventional method
Capsule.
Folium cortex eucommiae is the dried leaf of the Eucommiaceae plant bark of eucommia.Folium cortex eucommiae character differentiates：This product is more broken, intact leaf flattening
Oval afterwards or oval, long 7-15cm, wide 3.5-7cm；Surface yellow green or yellowish-brown, micro- glossy, tip is tapering, base
Portion is circular or wide wedge shape, edge tool sawtooth, has short petiole；Matter is crisp, and that rubs with the hands is frangible, and plane of rupture has a small amount of silvery white rubber thread phase
Even；Gas is micro-, mildly bitter flavor.The main chemical compositions of folium cortex eucommiae have：Chlorogenic acid, gutta-percha, ulmoprenol, catechol, protein, amino
Acid etc..Monarch drug in a prescription is used as in the herbal composite of folium cortex eucommiae in the present invention.Nature and flavor：It is micro-pungent, warm-natured；Channel tropism：Enter kidney, Liver Channel；
Effect：Filling liver kidney, strengthening the bones and muscles, hypotensive.High fat of blood main reason mainly has stagnant phlegm resistance, the liver and gall stasis of blood, the deficiency of liver-yin and kidney-yin, spleen kidney
The deficiency of yang.Folium cortex eucommiae liver-kidney tonifying, invigorating the spleen for eliminating dampness, strengthen muscles and bones, let out damp and hot, solution high fat of blood disease clearly.Folium cortex eucommiae function is mended simultaneously
Liver and kidney benefiting, functions dispelling wind and clearing away cold, removing dampness；It is nourishing liver and kidney, channels sootheing and network vessel quickening；Anti-trioxypurine.
Chrysanthemum is the dry capitulum of composite family herbaceos perennial chrysanthemum.Chrysanthemum character differentiates：Capitulum, outer layer flower
Valve (ligulate flower) is in flat single sheet more, and discoid (the most tubular flowers are polymerized) base portion fickle in love that there is yellow centre has green
Flower pedicle, it is made up of 3~4 layers of leaf (phyllary).Gas delicate fragrance, sweet and slightly bitter taste.Due to producing region and processing method difference (actual product
Kind differs), each local specialties slightly have difference.Main chemical compositions have：Chrysanthemum glucoside, apiolin, acacetin, galactopyranoside, wood
Rhinoceros grass element, Quercetin etc..Chrysanthemum nature and flavor：It is pungent, bitter, be slightly cold；Channel tropism：Return lung, Liver Channel；Effect：It is clearing heat and detoxicating, dispelling wind soothing the liver, resist
Virus.The diseases such as furunculosis carbuncle swells, abscess of throat, wind-fire red eye, dizziness of having a headache can be treated.Chrysanthemum indicum cold nature, tool dispelling wind and heat from the body,
Subdhing swelling and detoxicating, the diseases such as furunculosis carbuncle swells, abscess of throat, wind-fire red eye, dizziness of having a headache can be treated.Chrysanthemum or chrysanthemum indicum are in the present invention
It is middle to be used as ministerial drug, dispelling wind and heat from the body, subdhing swelling and detoxicating, the effect of strengthening monarch drug in a prescription folium cortex eucommiae, while because it is slightly cold, clearing heat and detoxicating medicine
Property, press down the warm nature of folium cortex eucommiae, have the function that temperature is cold and mutually make.
Rhizoma Gastrodiae is the dry tuber of orchid rhizoma Gastrodiae.Character differentiates：Stem tuber oblong, it is slightly flat, shrinkage and bend, greatly
It is small to differ, it is long 5~15 centimetres, it is wide 2~7 centimetres, it is thick 0.3~2 centimetre.Surface yellow-white or light brown, translucent, there is stem upper end
Trace, or the bud of reddish yellow, address " parrot mouth " or " red plait " is practised, there is discoid recessed navel lower end.All more longitudinal furrows, and have wiping
Fall the nodular ring grain of scale leaf formation.Matter is hard, is not easily broken, and section is flat, cutin shape, yellowish white or light brown.Do not steam
Slightly white quarrel, shows crack sometimes among person.Gas is micro-, sweet, micro-pungent.Main chemical compositions have：Gastrodin (Gastrodin), gastrodin
Member, rhizoma Gastrodiae ether glucoside, Pai Lixin, vanillyl alcohol, the sterols of β 2, citric acid, butanedioic acid etc..Rhizoma Gastrodiae nature and flavor：It is sweet, flat；Channel tropism：Enter Liver Channel；
Function：It is calming the liver to stop the wind, arresting convulsion.Rhizoma Gastrodiae makes for assistant in the present invention, with wind-dispelling antispastic contraction, calmness, eases pain, be anticonvulsion to help, leading monarch
Medicine ministerial drug solution dizziness and headache, twitch, makes monarch drug in a prescription ministerial drug play a role to the mind.
The clinical evaluating drug effect of Chinese medicine composition provided by the invention：
High fat of blood 20 is chosen, each 10 of men and women, the age, the course of disease 2~20 years, T-CHOL surpassed between 40 to 75 years old
10mmol/L is crossed, wherein 3 males have high fat of blood and hyperuricemia simultaneously, blood uric acid is above 400 μm of ol/L.Take reality
Apply the preparation of the preparation of example 2.Every is taken 1 dose, on an empty stomach, is divided in 2~3 times one day and is taken, during which do not take other medicines, during
Monitor blood fat and blood pressure.Blood fat and uric acid are monitored after 5 days.Experimental result：20 whole blood fat and uric acid are normal, and T-CHOL is equal
Between 2.5~3.5mmol/L, the patient of 3 concurrent hyperuricemias, blood uric acid value is below 300 μm of ol/L.Experiment terminates
Afterwards, the T-CHOL of patient and blood uric acid value are in normal range (NR).
It is alternative to take Patients with Hyperuricemia 20, male 15, women 5, the age between 40 to 75 years old, the course of disease 1~
15 years, blood uric acid value male was higher than 400 μm of ol/L, and women is higher than 350 μm of ol/L.Take the preparation of the preparation of embodiment 3, every clothes
With 1 dose, on an empty stomach, divide in 2~3 times one day and take, during which do not take other medicines.Blood uric acid value is monitored after 5 days.Experimental result 15
The blood uric acid value of example male patient is down to 290 μm of below ol/L, and the blood uric acid value of 5 female patients is down to 220 μm of ol/L
Below.After experiment terminates, the blood uric acid value of patient is in normal range (NR).
The clinical evaluating drug effect of preparation is close with above-mentioned experimental result in embodiment 1,5,6, total after 5 days after patient medication
Cholesterol and blood uric acid value are in normal range (NR), and here is omitted.
Herbal composite provided by the invention has good reducing blood lipid and anti-trioxypurine effect, and dose is few, takes
Simply, make suitable for prepared by reducing blood lipid and the use of anti-trioxypurine medicine preparation or auxiliary reducing blood lipid and anti-trioxypurine efficiency health-care food
With.During taking, patient does not occur adverse reaction, it was demonstrated that this herbal composite is without obvious toxic side effect.This medium-height grass
Drug composition to normal population without reducing blood lipid and anti-trioxypurine effect, to body non-evident effect.
Several embodiments of the present invention are described in detail above, but the content is only the preferable implementation of the present invention
Example, it is impossible to be considered as the practical range for limiting the present invention.All equivalent changes made according to the present patent application scope and improvement
Deng, all should still belong to the present invention patent covering scope within.
Claims (10)
1. application of the Chinese medicine composition in reducing blood lipid or anti-trioxypurine medicine is prepared, Chinese medicine composition fraction meter by weight
Calculate, including following components：20 parts of folium cortex eucommiae, rhizoma Gastrodiae 0.05-2 parts and chrysanthemum or chrysanthemum indicum 1-10 parts.
2. application according to claim 1, it is characterised in that：Chinese medicine composition fraction by weight calculates, including with
Lower component：20 parts of folium cortex eucommiae, rhizoma Gastrodiae 0.1-1 parts and chrysanthemum or chrysanthemum indicum 1-5 parts.
3. application according to claim 1 or 2, it is characterised in that：The chrysanthemum is Bo chrysanthemum, chu chrysanthemum, tribute chrysanthemum and Hang Juzhong
One or more of mixtures.
4. according to any described applications of claim 1-3, it is characterised in that：Also include in the reducing blood lipid or anti-trioxypurine medicine
Pharmaceutically acceptable pharmaceutic adjuvant.
5. application according to claim 4, it is characterised in that：The formulation of the reducing blood lipid or anti-trioxypurine medicine is oral
Liquid, pill, granule, tablet, electuary, syrup, powder, freeze-dried powder or capsule.
6. application of the Chinese medicine composition in reducing blood lipid or anti-trioxypurine health products are prepared, Chinese medicine composition fraction meter by weight
Calculate, including following components：20 parts of folium cortex eucommiae, rhizoma Gastrodiae 0.05-2 parts and chrysanthemum or chrysanthemum indicum 1-10 parts.
7. application according to claim 6, it is characterised in that：Chinese medicine composition fraction by weight calculates, including with
Lower component：20 parts of folium cortex eucommiae, rhizoma Gastrodiae 0.1-1 parts and chrysanthemum or chrysanthemum indicum 1-5 parts.
8. the application according to claim 6 or 7, it is characterised in that：The chrysanthemum is Bo chrysanthemum, chu chrysanthemum, tribute chrysanthemum and Hang Juzhong
One or more of mixtures.
9. according to any described applications of claim 6-8, it is characterised in that：Also wrapped in the reducing blood lipid or anti-trioxypurine health products
Include the acceptable auxiliary material of field of health care food.
10. application according to claim 9, it is characterised in that：The reducing blood lipid or anti-trioxypurine health products are oral liquid, glue
Capsule, tea-drinking or electuary.
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Application publication date: 20171208 |