CN107412126A - A kind of moisturiser based on marine organism extract - Google Patents
A kind of moisturiser based on marine organism extract Download PDFInfo
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- CN107412126A CN107412126A CN201710663931.3A CN201710663931A CN107412126A CN 107412126 A CN107412126 A CN 107412126A CN 201710663931 A CN201710663931 A CN 201710663931A CN 107412126 A CN107412126 A CN 107412126A
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- Prior art keywords
- extract
- moisturiser
- sponge
- ethanol
- urechis uniconctus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Zoology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of moisturiser based on marine organism extract, the moisturiser includes sponge extract and Urechis uniconctus extract.The mass fraction of the sponge extract added in the moisturiser is 1 2%, Urechis uniconctus extract 1 2%.The preparation method of sponge extract：Sponge is subjected to vacuum freeze-drying first, smashes and sieves, then carries out ethanol immersion, ultrasonic extraction, ethanol extract is concentrated again, and vacuum is outstanding to be evaporated off ethanol, obtains sponge extract.The present invention is used as moisturizing factor by the use of sponge extract and Urechis uniconctus extract, by experimental verification, the water content of skin can be effectively improved by demonstrating two kinds of preserving moisture and protecting skin compositions of sponge extract and Urechis uniconctus extract that the present invention adds, and high-moisture persistence, effectively enhancing skin elasticity, prevents skin senescence.
Description
Technical field
The present invention relates to natural marine organism extract, and in particular to is a kind of moisturiser based on marine organism extract
And its manufacture craft, belong to Nature inorganic bone field and daily cosmetics technical field.
Background technology
' skin-protecting ocean ' concept is more and more hotter in recent years, and many world-class skin care daily use chemicals famous brands begin one's study ocean life
The skin care performance of thing, it is concentrated mainly on moisturizing, anti-aging and crease-resistant etc..When human skin's cuticula moisture is less than
When 10%, crowfoot cracks and coarse can occur for skin, and moisture retention is one of important effect of cosmetics.Great amount of hydroxy group and carboxylic be present in polysaccharide
The hydrophilic radicals such as base, be a kind of bioactive polysaccharide, there are some excellent physicochemical properties, as strong absorptive, emulsibility and
Good film forming.Polysaccharide is applied to cosmetics, moisturizing can be produced, improve the functions such as the colour of skin, anti-aging and antibacterial, and high score
Sub- polysaccharide has no toxic side effect, good with the compatibility of conventional cosmetic composition, and therefore, polysaccharide has as effect type cosmetic humectant
Very wide application prospect.
And marine protein either polypeptide active substance is used for anti-aging and smoothing wrinkle performance study, oceanic shellfish active peptide
Containing abundant free amino acid in powder, wherein serine, glycine, threonine and alanine is moisturizing natural in cuticula
The factor, methionine and cysteine are keratin important composition compositions, and glycine, proline and alanine are that collagen is important
Constituent.Arginine energy vasodilator, promote cutaneous blood flow and metabolism.Glutamatergic promotes cell propagation and divided
Change, promote collagen generation and wound healing.Ornithine can improve blood flow, promote cell propagation and skin regeneration.Egg
Propylhomoserin and histidine have antioxidation activity, and glutamic acid and cysteine do not only have antioxidation activity, also suppress tyrosine enzyme activity
Property, so as to protect the skin from ultraviolet injury, and melanin generation can be suppressed.
Patent CN 105012217A, a kind of preserving moisture and protecting skin frost and its preparation technology based on marine extracts, described sea
Foreign extract active matter is the combination in algae extract, ocean water extract, Deep-Sea Microorganisms extract；Algae extract is
0.01-20%, ocean water extract are 0.01-20%, and Deep-Sea Microorganisms extract is 0.01-10%, and algae extract contains
The polyoses extract of HMW, one layer of ventilative film can be formed in skin surface, effectively prevent scattering and disappearing for moisture in skin；Can
Stimulate fibrocyte to go to manufacture more colloids, elasticin matter and mucopolysaccharide etc., accelerate the cell growth of epidermis, promote skin
The metabolism of skin, prevent skin senescence.
Patent No. CN 101348507B, a kind of moisture-absorption humectant of carboxymethyl mycose and its preparation, by effectively closing
The carboxymethyl mycose obtained into means, production cost raising is little, and moisture-absorbing moisture-keeping performance is obviously improved.Trehalose have compared with
Strong radioresistance and moisture-keeping functions so that it is also widely used on cosmetics.So as to which the present invention makees carboxymethyl mycose
For moisture-absorption humectant, its moisture-absorbing moisture-keeping performance is higher than hyaluronic acid, and carboxymethyl mycose cost is low, yield is high.
Obtained by above-mentioned, research of the marine organism extract in terms of skin care item is extensive, and all achieves good skin care
Effect.
Sponge is fixed on seabed, lacks the defence in muscle power, and in order to survive, to produce having for some new structures anti-
The metabolite of imperial function.Thus, the microorganism on sponge and sponge can produce the stronger material of various active, such as peptide
Class, polysaccharide, alkaloids, biological ketone etc..
Urechis uniconctus are seabed mollusks, and its nutritive value can match in excellence or beauty with sea cucumber, and Urechis uniconctus can be secreted greatly
The stickum of amount, contain various active composition.
The content of the invention
It is an object of the invention to provide a kind of moisturiser based on marine organism extract, with sponge extract and monocyclic thorn
Yi is main moisturizing factor, and a kind of splendid moisturiser of performance of keeping humidity is made.
To reach above-mentioned purpose, the concrete technical scheme that the present invention takes is：
A kind of moisturiser based on marine organism extract, the moisturiser includes sponge extract and Urechis uniconctus extract
Thing.
Further, the mass fraction of the sponge extract added in the moisturiser is 1-2%, Urechis uniconctus extract
1-2%.
Further, above-mentioned sponge is Halichodria rugosa (Halichondria rugosaRidley＆Dendy).
Further, the preparation method of above-mentioned sponge extract：Sponge is subjected to vacuum freeze-drying first, smashes and sieves, then
Ethanol immersion, ultrasonic extraction are carried out, ethanol extract is concentrated again, and vacuum is outstanding to be evaporated off ethanol, obtains sponge extract.
Further, the mass fraction of above-mentioned ethanol is 75-95%；The solid-liquid ratio for adding ethanol is 1：15-25.
Further, the mesh number that above-mentioned sponge is sieved after smashing is 10-30 mesh.
Further, above-mentioned carry out ultrasonic extraction 1-2h.
Further, it is above-mentioned carry out ultrasonic extraction again after, then carry out Microwave Extraction 30-60min.
Further, the preparation method of above-mentioned Urechis uniconctus extract：Fresh Urechis uniconctus are taken to add water grinding mashing, so
After centrifuged, sediment repeated washing is multiple, be incorporated in centrifugate, be then centrifuged for liquid add 70-80% ethanol enter
Row is sufficiently stirred extraction, and standing obtains supernatant, then is centrifuged, and obtains centrifugate, then it is concentrated, that is, obtains monocyclic
Pierce Yi extracts.
The advantages of the present invention are：
The present invention produces each as moisturizing factor, sponge by the use of sponge extract due to parasitic microbe, microbial metabolism
Kind secondary species, rich in various active material, including polysaccharide, steroid and polypeptide etc., and due to being secondary metabolite,
Molecular weight is smaller, and cutaneous permeability is good, not only rests on skin surface, can even more infiltrate into skin corium, repairs damaged skin,
Moisturizing factor is provided.
Sponge shows porous state in itself, and adsorption capacity is extremely strong, therefore has good water lock effect.Polysaccharide has
There is splendid performance of keeping humidity, there is good film forming, keep moisture, prevent the quick loss of moisture of skin.Peptides can repair
Multiple skin, improves skin vigor and elasticity, steroid balance skin electrolyte, increases the immunity of skin, and it is external to improve skin
The defence capability of boundary's harmful substance and ultraviolet, recover the health status of skin.
In addition, Urechis uniconctus can secrete a large amount of mucus, come multiple biological activities composition, effect containing polysaccharide, alkaloid
Comparable to sea cucumber, polysaccharide performance of keeping humidity is splendid, and the polyoses extract of every kind of marine organisms all has unique life characteristic.
By experimental verification, it was demonstrated that the sponge extract of the invention added, Urechis uniconctus extract two kinds of preserving moisture and protecting skins
Composition can effectively improve the water content of skin, and high-moisture persistence, effectively strengthen skin elasticity, prevent skin senescence.
Embodiment
The present invention is explained further and illustrated below by way of specific embodiment.
Embodiment 1：Active component extracts
The preparation method of sponge extract：Sponge is subjected to vacuum freeze-drying first, smashes and sieves, then carries out ethanol immersion,
Ultrasonic extraction, ethanol extract are concentrated again, and vacuum is outstanding to be evaporated off ethanol, obtains sponge extract.
Further, the mass fraction of above-mentioned ethanol is 75-95%；The solid-liquid ratio for adding ethanol is 1：15-25.
Further, the mesh number that above-mentioned sponge is sieved after smashing is 10-30 mesh.
Further, above-mentioned carry out ultrasonic extraction 1-2h.
Further, it is above-mentioned carry out ultrasonic extraction again after, then carry out Microwave Extraction 30-60min.
Active component made from the embodiment is used for the preparation of the moisturiser of embodiment 2.
The preparation method of Urechis uniconctus extract：Fresh Urechis uniconctus are taken to add mass ratio 1:The grinding mashing of 1-2 water, then
Centrifuged, sediment repeated washing is multiple, it is incorporated in centrifugate, is then centrifuged for the ethanol progress that liquid adds 70-80%
Extraction is sufficiently stirred, standing obtains supernatant, then is centrifuged, and obtains centrifugate, then it is concentrated, that is, obtains monocyclic thorn
Yi extracts.
Embodiment 2：
A kind of moisturiser based on marine organism extract, including following components, according to mass fraction：
Glycerine 3.8%
Butanediol 1.8%
EDTA-2Na 0.8%
Sodium Hyaluronate 3.2%
Hexylene glycol 0.3%
Hexadecanol 0.6%
Octadecyl alcolol 0.6%
Stearic acid list glyceride 0.5%
Shea butter 1.6%
Nexbase 2004 1.2%
Jojoba oil 2.0%
Triglycerides 3.0%
Sponge extract 2%, Urechis uniconctus extract 2%, surplus are water.
Embodiment 3
A kind of moisturiser, including following components, according to mass fraction：
Extract solution from aloe 2%
Glycerine 3.8%
Butanediol 1.8%
EDTA-2Na 0.8%
Sodium Hyaluronate 3.2%
Hexylene glycol 0.3%
Hexadecanol 0.6%
Octadecyl alcolol 0.6%
Stearic acid list glyceride 0.5%
Shea butter 1.6%
Nexbase 2004 1.2%
Jojoba oil 2.0%
Triglycerides 3.0%, surplus are water.
Moisturiser made from embodiment 2 and 3 is actually used：
Empirical tests first, two kinds of face creams not sensitization, 10 triers are randomly divided into two groups, after cleaning face, under measurement
Moisture content of skin, moisture content of skin is detected after smearing the moisturiser of equivalent, respectively detected once again by 1h, 2h and 6h respectively.By
Testing result can obtain, and moisturiser made from embodiment 2 and 3 can effectively improve the moisture-holding capacity after having cleaned face, but implement
The water conservation persistence of example 2 will apparently higher than embodiment 3, after 6h, the water content of the trier of embodiment 2 still more than 60.5%, and
Embodiment 3 will be generally less than 35%, and illustrate that of the invention the sponge extract added and Urechis uniconctus extract have can be effective
Improve and keep the water content of skin.
Claims (9)
1. a kind of moisturiser based on marine organism extract, it is characterised in that the moisturiser includes sponge extract and monocyclic
Pierce Yi extracts.
2. moisturiser as claimed in claim 1, it is characterised in that the quality of the sponge extract added in the moisturiser point
Number is 1-2%, and Urechis uniconctus extract is 1-2%.
3. moisturiser as claimed in claim 1, it is characterised in that above-mentioned sponge is Halichodria rugosa.
4. moisturiser as claimed in claim 1, it is characterised in that the preparation method of above-mentioned sponge extract：First by sponge
Carry out vacuum freeze-drying, smash sieving, then carry out ethanol immersion, ultrasonic extraction, ethanol extract is concentrated again, and vacuum is outstanding to steam
Ethanol is removed, obtains sponge extract.
5. moisturiser as claimed in claim 4, it is characterised in that the mass fraction of above-mentioned ethanol is 75-95%；Add ethanol
Solid-liquid ratio be 1：15-25.
6. moisturiser as claimed in claim 4, it is characterised in that the mesh number that above-mentioned sponge is sieved after smashing is 10-30 mesh.
7. moisturiser as claimed in claim 4, it is characterised in that above-mentioned carry out ultrasonic extraction 1-2h.
8. moisturiser as claimed in claim 4, it is characterised in that it is above-mentioned carry out ultrasonic extraction again after, then carry out microwave and carry
Take 30-60min.
9. moisturiser as claimed in claim 1, it is characterised in that the preparation method of the Urechis uniconctus extract is：Take new
Fresh Urechis uniconctus add water grinding mashing, are then centrifuged, and sediment repeated washing is multiple, are incorporated in centrifugate, then
The ethanol that centrifugate adds 70-80% carries out being sufficiently stirred extraction, and standing obtains supernatant, then is centrifuged, and is centrifuged
Liquid, then it is concentrated, that is, obtain Urechis uniconctus extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710663931.3A CN107412126A (en) | 2017-08-06 | 2017-08-06 | A kind of moisturiser based on marine organism extract |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710663931.3A CN107412126A (en) | 2017-08-06 | 2017-08-06 | A kind of moisturiser based on marine organism extract |
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| Publication Number | Publication Date |
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| CN107412126A true CN107412126A (en) | 2017-12-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710663931.3A Pending CN107412126A (en) | 2017-08-06 | 2017-08-06 | A kind of moisturiser based on marine organism extract |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113583084A (en) * | 2021-07-28 | 2021-11-02 | 中日友好医院(中日友好临床医学研究所) | Urechis unicinctus leach liquor protein extract and extraction method and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015606A (en) * | 2006-12-14 | 2007-08-15 | 刁勇 | Traditional Chinese medicine composition for preventing and treating cardiovascular and cerebrovascular diseases and preparing process thereof |
| CN102018652A (en) * | 2010-10-19 | 2011-04-20 | 广东雅倩化妆品有限公司 | Binary moisturizing system |
| CN105085694A (en) * | 2014-05-21 | 2015-11-25 | 浙江海洋学院 | Preparation method of urechis unicinctus viscera glycosaminoglycan and application thereof |
| CN106974880A (en) * | 2017-04-24 | 2017-07-25 | 泉州乃特尔机械科技有限公司 | A kind of moisturiser based on marine organism extract |
-
2017
- 2017-08-06 CN CN201710663931.3A patent/CN107412126A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015606A (en) * | 2006-12-14 | 2007-08-15 | 刁勇 | Traditional Chinese medicine composition for preventing and treating cardiovascular and cerebrovascular diseases and preparing process thereof |
| CN102018652A (en) * | 2010-10-19 | 2011-04-20 | 广东雅倩化妆品有限公司 | Binary moisturizing system |
| CN105085694A (en) * | 2014-05-21 | 2015-11-25 | 浙江海洋学院 | Preparation method of urechis unicinctus viscera glycosaminoglycan and application thereof |
| CN106974880A (en) * | 2017-04-24 | 2017-07-25 | 泉州乃特尔机械科技有限公司 | A kind of moisturiser based on marine organism extract |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113583084A (en) * | 2021-07-28 | 2021-11-02 | 中日友好医院(中日友好临床医学研究所) | Urechis unicinctus leach liquor protein extract and extraction method and application thereof |
| CN113583084B (en) * | 2021-07-28 | 2023-07-28 | 中日友好医院(中日友好临床医学研究所) | Urechis unicinctus leaching solution protein extract and extraction method and application thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171201 |
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| RJ01 | Rejection of invention patent application after publication |