CN107412101A - A kind of anti-aging, the Essence for promoting cytothesis and preparation method thereof - Google Patents

A kind of anti-aging, the Essence for promoting cytothesis and preparation method thereof Download PDF

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CN107412101A
CN107412101A CN201710695157.4A CN201710695157A CN107412101A CN 107412101 A CN107412101 A CN 107412101A CN 201710695157 A CN201710695157 A CN 201710695157A CN 107412101 A CN107412101 A CN 107412101A
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parts
essence
premix
skin
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付明远
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4993Derivatives containing from 2 to 10 oxyalkylene groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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Abstract

The invention provides a kind of anti-aging, the Essence for promoting cytothesis and preparation method thereof.The Essence, using various active composition, such as ursin, primrose essential oil, snail secretion filtrate, extract solution from aloe, SP, epiphysin and peptone, plurality of active ingredients collective effect, serve and enhance metabolism, Cucumber Extract cell, improve microcirculation, increase the effect of skin tight ness rating;Most of all, in the Essence, polynucleotides are added, polynucleotides are extracted from the DNA of salmon, can be delivered to the skin corium of skin, improve the physiological condition inside impaired skin, skin internal environment state is recovered normal, fundamentally solve the problems, such as skin.The preparation method, according to the property of different material, different raw materials is grouped respectively, and the Essence of positive effect is finally given using different processing methods.

Description

A kind of anti-aging, the Essence for promoting cytothesis and preparation method thereof
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of anti-aging, promote cytothesis Essence and its Preparation method.
Background technology
The aging of human body is the inexorable law of life growth, wherein the most obvious with the change of skin, general women is 25 After year, skin is in falling tendency, and after 30 years old, aging makes first appearance.Skin senescence refers to that skin surface is coarse and wrinkles Line.Skin aging is a progressive physiology course, and the knot of the various factors comprehensive function such as heredity, environment, social mentality Fruit.
Specifically, the form of skin senescence is mainly that naturally-aged (i.e. endogenous aging) and light aging are (i.e. exogenous Aging), naturally-aged is mainly caused by body inherent cause, is limited to systemic sites, hence it is evident that is characterized as wrinkle and relaxation, and occurs Phenomena such as pigmentation.Light aging is mainly the skin senescence caused by ultraviolet damage accumulation, is that naturally-aged and ultraviolet shine Coefficient result is penetrated, is limited to skin exposure portion, is mainly characterized by pachylosis tarnish, steady overstriking is walked and deepens, pigment Calmness is deepened, and skin microcirculation is deteriorated, elastosis, and epidermis shows as removing power, collagen and elastin laminin synthesis Ability and immunity degradation, phenomena such as dermis thickness is thinning, easy generation allergy inflammation.Ultraviolet irradiation can make melanin produce Change, a kind of material for protecting skin is generated, then melanin and moving layer by layer via cell metabolism, have arrived skin epidermis Layer, forms color spot that we are seen now and the skin problems such as the colour of skin is irregular;And to produce skin pore thicker, oily after shining The skin problems such as fat hypersecretion, moisture of skin deficiency.
As the improvement of people's living standards, the functional requirement more and more higher to skin care item, possesses the shield of anti-aging effects Skin product also emerge in an endless stream.It is the most frequently used at present, it is toner and Essence.
Toner is a kind of cosmetics of transparent liquid, is applied to the surface of skin, for cleaning skin, keeping skin Health, it is the essential articles for use of the daily beauty and skin care of people.But when skin because season alternation becomes coarse drying;Because of pressure It is overweight to become tired unglazed;The equilibrium of skin script is destroyed because being tanned severely long-distance travel, long-time;Because of age or hormone Change and when there is aging, generally require to use Essence.
Essence, containing trace element, collagen, serum, its effect has anti-aging, crease-resistant, moisturizing, whitening, gone Spot etc..Essence is a kind of good skin care item, it unlike concealer, foundation cream, loose powder, muffin these can only temporarily cover skin Skin is gloomy, and conditioned in skin quality in, and radical cure influences arch-criminal's melanin of whitening, and skin can just show really by interior And outer natural beauty white light is color.
At present, the species of Essence is various, but mostly expensive, and main component therein is often chemical work , more side effect be present, be not suitable for long-term use in the material of industry synthesis.
The content of the invention
In order to solve above mentioned problem existing for prior art, the invention provides a kind of anti-aging, promote cytothesis Essence and preparation method thereof.The Essence can face-beautifying sanility-delaying, enhance metabolism, Cucumber Extract cell, improve it is micro- Circulation, increase skin tight ness rating;And wherein contain a large amount of bioactive substances, it is quick, security is good, suitably make for a long time With.
The technical solution adopted in the present invention is:A kind of anti-aging, the Essence for promoting cytothesis, including following weight The raw material of part:Tea oil 10-15 parts, tocopherol acetate 5-7 parts, niacinamide 0.5-1 parts, hyaluronic acid 10-20 parts, saualane 5- 9 parts, aspartic acid 1-3 parts, glycerine 12-16 parts, ursin 2-4 parts, primrose essential oil 7-9 parts, snail secretion filtrate 13-15 Part, carbomer 6-10 parts, extract solution from aloe 10-14 parts, Co-Q10 0.3-0.5 parts, SP 3-5 parts, epiphysin 0.05-0.1 Part, collagen 4-6 parts, polynucleotides 1-3 parts, Phenoxyethanol 6-8 parts, peptone 5-10 parts and deionized water 15-25 parts.
The Essence, carried using various active composition, such as ursin, primrose essential oil, snail secretion filtrate, aloe Liquid, SP, epiphysin and peptone are taken, plurality of active ingredients collective effect, serves and enhances metabolism, Cucumber Extract is thin Born of the same parents, improve microcirculation, increase the effect of skin tight ness rating;Most of all, in the Essence, polynucleotides are added, it is more Nucleotides is extracted from the DNA of salmon, can be delivered to the skin corium of skin, improves the physiological condition inside impaired skin, Skin internal environment state is recovered normal, fundamentally solve the problems, such as skin.
According to one embodiment of present invention, the Essence includes the raw material of following parts by weight:10 parts of tea oil, tocopherol 7 parts of acetic acid esters, 0.5 part of niacinamide, 20 parts of hyaluronic acid, 5 parts of saualane, 3 parts of aspartic acid, 12 parts of glycerine, 4 parts of ursin, 7 parts of primrose essential oil, 15 parts of snail secretion filtrate, 6 parts of carbomer, 14 parts of extract solution from aloe, 0.3 part of Co-Q10, SP 5 Part, 0.05 part of epiphysin, 6 parts of collagen, 1 part of polynucleotides, 8 parts of Phenoxyethanol, 5 parts of peptone and 25 parts of deionized water.
According to one embodiment of present invention, the Essence includes the raw material of following parts by weight:15 parts of tea oil, tocopherol 5 parts of acetic acid esters, 1 part of niacinamide, 10 parts of hyaluronic acid, 9 parts of saualane, 1 part of aspartic acid, 16 parts of glycerine, ursin 2 part, month See careless 9 parts of essential oil, 13 parts of snail secretion filtrate, 10 parts of carbomer, 10 parts of extract solution from aloe, 0.5 part of Co-Q10, SP 3 Part, 0.1 part of epiphysin, 4 parts of collagen, 3 parts of polynucleotides, 6 parts of Phenoxyethanol, 10 parts of peptone and 15 parts of deionized water.
For the effect for obtaining more preferable anti-aging, promoting cytothesis, preferable technical scheme is the Essence bag Include the raw material of following parts by weight:12 parts of tea oil, 6 parts of tocopherol acetate, 0.7 part of niacinamide, 15 parts of hyaluronic acid, saualane 7 Part, 2 parts of aspartic acid, 14 parts of glycerine, 3 parts of ursin, 8 parts of primrose essential oil, 14 parts of snail secretion filtrate, 8 parts of carbomer, 12 parts of extract solution from aloe, 0.4 part of Co-Q10,4 parts of SP, 0.07 part of epiphysin, 5 parts of collagen, 2 parts of polynucleotides, benzene 20 parts of 7 parts of oxyethanol, 7 parts of peptone and deionized water.
For the ease of understanding the present invention, the raw material in the present invention is further elaborated below:
Tea oil, also known as camellia oil, camellia seed oil, it is the C. olelfera (Camellia from Theaceae Camellia Plants Oleifera Abel) pure natural high edible vegetable oil extracted in mature seed.Tea oil energy ultraviolet light, prevent sunburn and Remove wrinkle;There are sterilization and enhancing immunization simultaneously.
Tocopherol acetate, can play prevents cell membrane and intracellular unsaturated lipid during body metabolism The oxidized effect of the readily oxidizable substances such as fat acid, so as to protect the complete of cell membrane and then prevent the effect of aging.
Niacinamide, most important effect is that mitigation and prevention skin produce in early stage aging course in terms of skin anti-aging The raw colour of skin is dull, turns to be yellow, famished look.Certainly, contribution this and more of the niacinamide to skin, can also repair impaired cutin Layer lipid barrier, improves skin resistance.The effect of may more also being ignored by people, it is exactly the deep layer water lock work(of niacinamide Effect, so, the skin care item containing niacinamide are to having extremely strong water lock, moisture-keeping efficacy.
Hyaluronic acid, more than 500 times of moisture can be carried, for the optimal moisturizing ingredient recognized by current, be widely applied In skin care products and cosmetics.
Saualane (Squalane), which is that the squalene extracted from hydrogenated hydro carbons grease is hydrogenated, is made a kind of excellent performance Squalene extracting, therefore also known as eepwater shark liver oil.Maintenance epidermis can be strengthened, be effectively formed natural diaphragm, help skin with Balance between sebum, saualane can also open skin pore, promote blood microcirculation, promote the metabolism of cell, help Repair damaged cell.
Aspartic acid, in the present invention, as peptone, as nutritive additive.
Glycerine, it is colourless sweet clear and bright thick liquid, in addition to moisturizing, humectation function, also with high activity, antioxygen Change, promote the special efficacies such as alcoholization.
Ursin also known as Arbutin, white acicular crystal or powder, extract the leaf from black bearberry, can be by suppressing body The activity of interior tyrosinase, the generation of melanin is prevented, so as to reduce Skin pigmentation, dispelling stain and freckle;Also simultaneously There are sterilization, anti-inflammatory.
Primrose essential oil, it is in the flower from oenothera biennis, leaf, stem, root or fruit, by steam distillation, extrusion, cold Leaching method or solvent extraction method refine the volatile flavor of extraction.The metabolism of sebaceous glands can be adjusted, improves cutaneous disorder and shows As acne and blackspot caused by treatment regulation endocrine.
Snail secretion filtrate, refer to the product of the mucus secreted in snail crawling process after filtering, when snail creeps The mucus of secretion can be effectively prevented from skin aging, and can eliminate spot, scar and acne on skin.Utilize the regeneration of snail The cold cream that effect makes is that pole has protective effect to skin.The chemical composition that the mucus of snail secretion contains has Firm work With skin rapid regeneration can be made.The allantoin extracted from snail mucus can make skin regeneration;Protein and vitamin The nutrition of skin can be increased, make skin finer and smoother and smooth.(in general, made using the mucus after filtering in the present invention With the strainer filtering of 200-1000 mesh), in order that impurity therein is filtered, use is safer.
Carbomer is the high molecular polymer that acrylic acid is bonded allyl sucrose or pentaerythrite allyl ether, in the present invention In, as hydrophily thickening agent, stabilising emulsifier, suspending agent, gel.
Extract solution from aloe, for the viscous liquid extracted from aloe, there is natural moisturizing and water lock effect, Neng Gouzeng Add NMF, increase water content immediately, percutaneous water loss is reduced by slight filming function, generally applicable cream, In the moisturizing wrinkle-removal cosmetic product such as emulsion, mildy wash, facial mask.
Co-Q10 (hydroxy decyl ubiquinone), is a kind of fat-soluble antioxidant, the battalion of energy human activin cell and cellular energy Support, have and improve body immunity, strengthen anti-oxidant, anti-aging and strengthen the functions such as human activity.
SP, it is the catabolite of silk-fibroin, is that natural silk obtains through being hydrolyzed under felicity condition, to be transparent yellowish Color liquid, molecular weight is about between 300-5000;Make with dermal melanin generation, good skin care moisturizing and hair care is suppressed With.
Epiphysin, also known as melatonin, U.S. drawing ketone is peaceful, presses down melanocyte, melatonin, is the pine by mammal and the mankind A kind of amine bormones caused by fruit body, a kind of cell for producing melanin (melanin) can be made shinny, thus be named as take off it is black Element.Melatonin peroxidization protection eucaryotic cell structure that is anti-oxidant and suppressing lipid, prevents DNA from damaging by removing free radical Hinder, reduce the content of internal peroxide.
Polynucleotides are nucleotide polymerizations into chain compound, the polynucleotides in the present invention, extract from salmon In DNA, the skin corium of skin can be delivered to, improves the physiological condition inside impaired skin, makes skin internal environment state extensive It is multiple normal, fundamentally solve the problems, such as skin.
Phenoxyethanol, it is a kind of colourless oily liquids, there is antibiotic effect, in cosmetics, skin care item, vaccine and medicine Generally play the function of preservative and fixative.
Peptone, peptone are will to dry the outward appearance formed in yellowish after meat, casein or gelatin acid or protease hydrolytic The pulvis of color.Protein can also form peptone after acid, alkali or proteases for decomposing.In the present invention, as aspartic acid, As nutritive additive.
Deionized water, refer to eliminate the pure water in after ionic species impurity.
Present invention also offers a kind of preparation method of the Essence, comprise the following steps:
A, tocopherol acetate, niacinamide, hyaluronic acid and deionized water are mixed, with 2200-2400r/min rotating speed After stirring 30-50s, 72-78 DEG C is heated to according to 5-8 DEG C/min programming rate, 4-6min is kept, obtains the first premix;
B, tea oil, saualane, glycerine, primrose essential oil, extract solution from aloe, Co-Q10, polynucleotides and peptone are mixed Close, after 1800-1900r/min rotating speed stirring 2-4min, be heated to 55-65 DEG C according to 3-5 DEG C/min programming rate, protect 1-2min is held, obtains the second premix;
C, aspartic acid, ursin, snail secretion filtrate, SP, epiphysin and collagen are mixed, with 1900- After 2000r/min rotating speed stirring 1-3min, 50-60 DEG C is heated to according to 1-3 DEG C/min programming rate, keeps 3-5min, Obtain the 3rd premix;
D, the first premix and the second premix are mixed, at 72-75 DEG C, stirred under 600-800r/min rotating speed 12-16min, then obtain first after the high-pressure homogeneous 12-14min and 8-12MPa low pressure homogeneous 5-7min of 25-35MPa successively Compound;
E, the first compound and the 3rd premix are mixed, stirred under 200-400r/min rotating speed, while stirring Carbomer and poly(ethylene oxide)polymers are added, compound are obtained after stirring, as described Essence.
In the present invention, according to the property of different material, different raw materials is grouped respectively, and uses different preparations Method respectively obtains different premix, and the Essence is finally given premix is mixed, and can ensure that each component plays Synergy, preferably plays face-beautifying sanility-delaying, enhances metabolism, Cucumber Extract cell, improves microcirculation, and increase skin is tight The effect of density.
To ensure that the more preferable Essence of effect is prepared, preferable technical scheme is, in step A, by tocopheryl acetate Ester, niacinamide, hyaluronic acid and deionized water mixing, after 2250-2350r/min rotating speed stirring 35-45s, according to 6-7 DEG C/min programming rate is heated to 72-78 DEG C, 5min is kept, then after the high-pressure homogeneous 12-14min of 25-35MPa, obtain First premix.
In step B, by tea oil, saualane, glycerine, primrose essential oil, extract solution from aloe, Co-Q10, polynucleotides and egg White peptone mixing, after 1830-1870r/min rotating speed stirring 3min, 58-62 DEG C is heated to according to 4 DEG C/min programming rate, 1-2min is kept, then after 8-12MPa low pressure homogeneous 5-7min, obtains the second premix.
In step C, aspartic acid, ursin, snail secretion filtrate, SP, epiphysin and collagen are mixed, with After 1930-1970r/min rotating speed stirring 1-3min, 53-57 DEG C is heated to according to 2 DEG C/min programming rate, keeps 4min, Obtain the 3rd premix.
In step D, the first premix and the second premix are mixed, at 73 DEG C, stirred under 650-750r/min rotating speed 14min is mixed, then obtains the first mixing after the high-pressure homogeneous 12-14min and 10MPa low pressure homogeneous 5-7min of 30MPa successively Material.
In step E, after carbomer and poly(ethylene oxide)polymers are stirred under 600-1000r/min rotating speed, first is added In compound and the 3rd premix, compound is cooled to room temperature and ageing 18-22h is placed at 22-24 DEG C, you can obtains institute State Essence.
Beneficial effects of the present invention are:
1st, the invention provides a kind of anti-aging, the Essence of promotion cytothesis, using various active composition, such as black bearberry Glycosides, primrose essential oil, snail secretion filtrate, extract solution from aloe, SP, epiphysin and peptone, plurality of active ingredients are common Effect, serves and enhances metabolism, and increase skin density and elasticity, lifts skin modelling effect, regulation oil-water balance, receives Contracting pore, sebum is reduced, improves skin texture, improves microgroove, regeneration skin diaphragm, the elite colour of skin and reduces cutin this ten big work( Effect;Most of all, in the Essence, polynucleotides are added, polynucleotides are extracted from the DNA of salmon, Neng Gouchuan It is delivered to the skin corium of skin, improves the physiological condition inside impaired skin, skin internal environment state is recovered normal, from basic It is upper to solve the problems, such as skin.
2nd, present invention also offers a kind of preparation method of the Essence, the preparation method is according to the property of different material Matter, different raw materials is grouped respectively, and different premix is respectively obtained using different preparation methods, will premixed Material mixing finally gives the Essence, can ensure that each component plays synergy, preferably play face-beautifying sanility-delaying, promote Metabolism, Cucumber Extract cell, improve microcirculation, increase the effect of skin tight ness rating.
Embodiment
With reference to embodiment, present disclosure is further illustrated.It should be appreciated that the implementation of the present invention is not limited to In the following examples, any formal accommodation and/or change made to the present invention fall within the scope of the present invention.
In the present invention, if not refering in particular to, all parts, percentage are unit of weight, and all equipment and raw material etc. are equal It is commercially available or the industry is conventional.Method in following embodiments, it is the routine of this area unless otherwise instructed Method.
Embodiment 1
A kind of anti-aging, the Essence for promoting cytothesis, include the raw material of following weight:Tea oil 10g, tocopheryl acetate Ester 7g, niacinamide 0.5g, hyaluronic acid 20g, saualane 5g, aspartic acid 3g, glycerine 12g, ursin 4g, primrose essential oil 7g, snail secretion filtrate 15g, carbomer 6g, extract solution from aloe 14g, Co-Q10 0.3g, SP 5g, epiphysin 0.05g, Collagen 6g, polynucleotides 1g, Phenoxyethanol 8g, peptone 5g and deionized water 25g.
The preparation method of the Essence, comprises the following steps:
A, tocopherol acetate, niacinamide, hyaluronic acid and deionized water are mixed, stirred with 2200r/min rotating speed After 50s, 78 DEG C are heated to according to 5 DEG C/min programming rate, keeps 4min, then after the high-pressure homogeneous 12min of 35MPa, obtain To the first premix;
B, tea oil, saualane, glycerine, primrose essential oil, extract solution from aloe, Co-Q10, polynucleotides and peptone are mixed Close, after 1900r/min rotating speed stirring 2min, be heated to 55 DEG C according to 5 DEG C/min programming rate, keep 2min, then pass through After crossing 8MPa low pressure homogeneous 7min, the second premix is obtained;
C, aspartic acid, ursin, snail secretion filtrate, SP, epiphysin and collagen are mixed, with 1900r/ After min rotating speed stirring 3min, 60 DEG C are heated to according to 1 DEG C/min programming rate, 3min is kept, obtains the 3rd premix;
D, the first premix and the second premix are mixed, at 75 DEG C, 16min is stirred under 600r/min rotating speed, then Successively after the high-pressure homogeneous 14min and 8MPa low pressure homogeneous 7min of 25MPa, the first compound is obtained;
E, after carbomer and poly(ethylene oxide)polymers stirring under 600r/min rotating speed, the first compound and the 3rd is added In premix, compound is obtained after being stirred under 400r/min rotating speed, compound is cooled to room temperature and at 24 DEG C Place ageing 18h, you can obtain the Essence.
Embodiment 2
A kind of anti-aging, the Essence for promoting cytothesis, include the raw material of following weight:Tea oil 15g, tocopheryl acetate Ester 5g, niacinamide 1g, hyaluronic acid 10g, saualane 9g, aspartic acid 1g, glycerine 16g, ursin 2g, primrose essential oil 9g, Snail secretion filtrate 13g, carbomer 10g, extract solution from aloe 10g, Co-Q10 0.5g, SP 3g, epiphysin 0.1g, collagen Albumen 4g, polynucleotides 3g, Phenoxyethanol 6g, peptone 10g and deionized water 15g.
The preparation method of the Essence, comprises the following steps:
A, tocopherol acetate, niacinamide, hyaluronic acid and deionized water are mixed, stirred with 2400r/min rotating speed After 30s, 72 DEG C are heated to according to 8 DEG C/min programming rate, keeps 6min, then after the high-pressure homogeneous 14min of 25MPa, obtain To the first premix;
B, tea oil, saualane, glycerine, primrose essential oil, extract solution from aloe, Co-Q10, polynucleotides and peptone are mixed Close, after 1800r/min rotating speed stirring 4min, be heated to 65 DEG C according to 3 DEG C/min programming rate, keep 1min, then pass through After crossing 12MPa low pressure homogeneous 5min, the second premix is obtained;
C, aspartic acid, ursin, snail secretion filtrate, SP, epiphysin and collagen are mixed, with 2000r/ After min rotating speed stirring 1min, 50 DEG C are heated to according to 3 DEG C/min programming rate, 5min is kept, obtains the 3rd premix;
D, the first premix and the second premix are mixed, at 72 DEG C, 12min is stirred under 800r/min rotating speed, then Successively after the high-pressure homogeneous 12min and 12MPa low pressure homogeneous 5min of 35MPa, the first compound is obtained;
E, after carbomer and poly(ethylene oxide)polymers stirring under 1000r/min rotating speed, the first compound and the are added In three premixes, compound is obtained after being stirred under 200r/min rotating speed, compound is cooled to room temperature and at 22 DEG C It is lower to place ageing 22h, you can to obtain the Essence.
Embodiment 3
A kind of anti-aging, the Essence for promoting cytothesis, include the raw material of following weight:Tea oil 12g, tocopheryl acetate Ester 6g, niacinamide 0.7g, hyaluronic acid 15g, saualane 7g, aspartic acid 2g, glycerine 14g, ursin 3g, primrose essential oil 8g, snail secretion filtrate 14g, carbomer 8g, extract solution from aloe 12g, Co-Q10 0.4g, SP 4g, epiphysin 0.07g, Collagen 5g, polynucleotides 2g, Phenoxyethanol 7g, peptone 7g and deionized water 20g.
The preparation method of the Essence, comprises the following steps:
A, tocopherol acetate, niacinamide, hyaluronic acid and deionized water are mixed, stirred with 2300r/min rotating speed After 40s, 75 DEG C are heated to according to 6 DEG C/min programming rate, keeps 5min, then after the high-pressure homogeneous 13min of 30MPa, obtain To the first premix;
B, tea oil, saualane, glycerine, primrose essential oil, extract solution from aloe, Co-Q10, polynucleotides and peptone are mixed Close, after 1850r/min rotating speed stirring 3min, be heated to 60 DEG C according to 4 DEG C/min programming rate, keep 1.5min, then After 10MPa low pressure homogeneous 6min, the second premix is obtained;
C, aspartic acid, ursin, snail secretion filtrate, SP, epiphysin and collagen are mixed, with 1950r/ After min rotating speed stirring 2min, 55 DEG C are heated to according to 2 DEG C/min programming rate, 4min is kept, obtains the 3rd premix;
D, the first premix and the second premix are mixed, at 73 DEG C, 14min is stirred under 700r/min rotating speed, then Successively after the high-pressure homogeneous 13min and 10MPa low pressure homogeneous 6min of 30MPa, the first compound is obtained;
E, after carbomer and poly(ethylene oxide)polymers stirring under 800r/min rotating speed, the first compound and the 3rd is added In premix, compound is obtained after being stirred under 300r/min rotating speed, compound is cooled to room temperature and at 23 DEG C Place ageing 20h, you can obtain the Essence.
Embodiment 4
A kind of anti-aging, the Essence for promoting cytothesis, include the raw material of following weight:Tea oil 11g, tocopheryl acetate Ester 7g, niacinamide 0.6g, hyaluronic acid 17g, saualane 6g, aspartic acid 3g, glycerine 13g, ursin 3g, primrose essential oil 8g, snail secretion filtrate 15g, carbomer 7g, extract solution from aloe 13g, Co-Q10 0.35g, SP 3.5g, epiphysin 0.08g, collagen 4.5g, polynucleotides 2.5g, Phenoxyethanol 7g, peptone 9g and deionized water 22g.
The preparation method of the Essence, comprises the following steps:
A, tocopherol acetate, niacinamide, hyaluronic acid and deionized water are mixed, stirred with 2250r/min rotating speed After 45s, 78 DEG C are heated to according to 6 DEG C/min programming rate, keeps 5min, then after the high-pressure homogeneous 14min of 25MPa, obtain To the first premix;
B, tea oil, saualane, glycerine, primrose essential oil, extract solution from aloe, Co-Q10, polynucleotides and peptone are mixed Close, after 1830r/min rotating speed stirring 3min, be heated to 62 DEG C according to 4 DEG C/min programming rate, keep 1min, then pass through After crossing 12MPa low pressure homogeneous 5min, the second premix is obtained;
C, aspartic acid, ursin, snail secretion filtrate, SP, epiphysin and collagen are mixed, with 1970r/ After min rotating speed stirring 1min, 57 DEG C are heated to according to 2 DEG C/min programming rate, 4min is kept, obtains the 3rd premix;
D, the first premix and the second premix are mixed, at 73 DEG C, 14min is stirred under 650r/min rotating speed, then Successively after the high-pressure homogeneous 14min and 10MPa low pressure homogeneous 5min of 30MPa, the first compound is obtained;
E, after carbomer and poly(ethylene oxide)polymers stirring under 1000r/min rotating speed, the first compound and the are added In three premixes, compound is obtained after being stirred under 200r/min rotating speed, compound is cooled to room temperature and at 24 DEG C It is lower to place ageing 18h, you can to obtain the Essence.
Embodiment 5
A kind of anti-aging, the Essence for promoting cytothesis, include the raw material of following weight:Tea oil 14g, tocopheryl acetate Ester 6g, niacinamide 0.8g, hyaluronic acid 13g, saualane 8g, aspartic acid 1g, glycerine 15g, ursin 2g, primrose essential oil 9g, snail secretion filtrate 14g, carbomer 9g, extract solution from aloe 11g, Co-Q10 0.4g, SP 4.5g, epiphysin 0.07g, collagen 5.5g, polynucleotides 1.5g, Phenoxyethanol 8g, peptone 6g and deionized water 17g.
The preparation method of the Essence, comprises the following steps:
A, tocopherol acetate, niacinamide, hyaluronic acid and deionized water are mixed, stirred with 2350r/min rotating speed After 35s, 72 DEG C are heated to according to 7 DEG C/min programming rate, keeps 5min, then after the high-pressure homogeneous 12min of 35MPa, obtain To the first premix;
B, tea oil, saualane, glycerine, primrose essential oil, extract solution from aloe, Co-Q10, polynucleotides and peptone are mixed Close, after 1870r/min rotating speed stirring 3min, be heated to 58 DEG C according to 4 DEG C/min programming rate, keep 2min, then pass through After crossing 8MPa low pressure homogeneous 7min, the second premix is obtained;
C, aspartic acid, ursin, snail secretion filtrate, SP, epiphysin and collagen are mixed, with 1930r/ After min rotating speed stirring 3min, 53 DEG C are heated to according to 2 DEG C/min programming rate, 4min is kept, obtains the 3rd premix;
D, the first premix and the second premix are mixed, at 73 DEG C, 14min is stirred under 750r/min rotating speed, then Successively after the high-pressure homogeneous 12min and 10MPa low pressure homogeneous 7min of 30MPa, the first compound is obtained;
E, after carbomer and poly(ethylene oxide)polymers stirring under 600r/min rotating speed, the first compound and the 3rd is added In premix, compound is obtained after being stirred under 400r/min rotating speed, compound is cooled to room temperature and at 22 DEG C Place ageing 22h, you can obtain the Essence.
Embodiment 6
The present embodiment is the stability test and effect test that the Essence obtained to above-described embodiment is carried out.
First, stability is tested
Essence in embodiment 3 is put into constant incubator, heat-resisting (45 ± 1 DEG C) experiments is carried out, places one month Afterwards, take out recovery to observing after room temperature, the Essence without aggregation, without float, without sinking, integral product is uniform, no discoloration;So After be put into refrigerator and carry out cold-resistant experiment (- 15 to -25 DEG C), after placing one month, observed after taking out recovery to room temperature, the essence Magnificent liquid without aggregation, without float, without sink, integral product it is uniform, no metachromatism;This process is tested for one cycle.Carry out Three times after circulation experiment, the Essence, no separation and metachromatism are observed after recovering room temperature.
The Essence can be subjected at least 3 times heat-resisting cold-resistant circulation experiments, illustrate the stability of the Essence very It is good.
2nd, effect test
1st, anti-crow's feet test
100 ages are selected, as tester, to have obvious crow's feet in the women of 30-35 year, be equally divided into 5 Group, the Essence that the face of 5 groups of subjects tries out embodiment 1-5 respectively are applied at crow's feet, respectively use 1 sooner or later daily It is secondary, share 30 days, observe trial effect, acquired results are shown in Table 1.
Test index:Obvious crow's feet for ×;Shallower crow's feet is zero;It is √ not have crow's feet;Test condition: (1) indoor environment;(2) without sunburst or light direct projection;(3) 20 ± 2 DEG C of environment temperature, ambient humidity 40-60%.
Table 1:Crow's feet test result
Group Obvious crow's feet for × Shallower crow's feet is zero It is √ not have crow's feet
1 2 13 5
2 2 14 4
3 1 9 10
4 1 12 7
5 1 13 6
From upper table, it can be seen that the Essence has strong anti-crow's feet effect, and comparative example 1-5 can It was found that the best results for the Essence that embodiment 3 obtains, embodiment 4 and 5 obtains Essence effect and taken second place, and is embodiment 1 again With 2 obtained Essences.
2nd, skin micro-relief graphical analysis
Select 100 ages in the women of 30-35 year as tester, be equally divided into 5 groups, before 5 groups of subjects The daily application of Essence that arm is obtained using 1-5 of the embodiment of the present invention 15 minutes, follow-on test 30 days, after test terminates, with figure Picture analysis method measures wrinkle depth on skin pull (silica replica), and side obtains every group of average value.To depth after 30 days The influence result of layer wrinkle is as shown in table 2:
Table 2:Image analytical method testing result
It can be seen that the Essence that the present invention obtains has extraordinary improvement result, and comparative example 1-5 to deep wrinkles It can be found that the best results for the Essence that embodiment 3 obtains, embodiment 4 and 5 obtains Essence effect and taken second place, and is real again Apply the Essence that example 1 and 2 obtains.
It should be noted last that the above embodiments are merely illustrative of the technical solutions of the present invention and it is unrestricted, although ginseng The present invention is described in detail according to preferred embodiment, should be understood that the specific implementation that the foregoing is only the present invention Mode, the protection domain being not intended to limit the present invention, within the spirit and principles of the invention, that is done any repaiies Change, equivalent substitution, improvement etc., should be included in the scope of the protection.

Claims (10)

1. a kind of anti-aging, the Essence for promoting cytothesis, it is characterised in that include the raw material of following parts by weight:Tea oil 10- 15 parts, tocopherol acetate 5-7 parts, niacinamide 0.5-1 parts, hyaluronic acid 10-20 parts, saualane 5-9 parts, aspartic acid 1-3 Part, glycerine 12-16 parts, ursin 2-4 parts, primrose essential oil 7-9 parts, snail secretion filtrate 13-15 parts, carbomer 6-10 Part, extract solution from aloe 10-14 parts, Co-Q10 0.3-0.5 parts, SP 3-5 parts, epiphysin 0.05-0.1 parts, collagen 4-6 Part, polynucleotides 1-3 parts, Phenoxyethanol 6-8 parts, peptone 5-10 parts and deionized water 15-25 parts.
2. Essence according to claim 1, it is characterised in that include the raw material of following parts by weight:10 parts of tea oil, fertility 7 parts of phenol acetic acid esters, 0.5 part of niacinamide, 20 parts of hyaluronic acid, 5 parts of saualane, 3 parts of aspartic acid, 12 parts of glycerine, ursin 4 Part, 7 parts of primrose essential oil, 15 parts of snail secretion filtrate, 6 parts of carbomer, 14 parts of extract solution from aloe, Co-Q10 0.3 part, thread 5 parts of peptide, 0.05 part of epiphysin, 6 parts of collagen, 1 part of polynucleotides, 8 parts of Phenoxyethanol, 5 parts of peptone and deionized water 25 Part.
3. Essence according to claim 1, it is characterised in that include the raw material of following parts by weight:15 parts of tea oil, fertility 5 parts of phenol acetic acid esters, 1 part of niacinamide, 10 parts of hyaluronic acid, 9 parts of saualane, 1 part of aspartic acid, 16 parts of glycerine, 2 parts of ursin, 9 parts of primrose essential oil, 13 parts of snail secretion filtrate, 10 parts of carbomer, 10 parts of extract solution from aloe, 0.5 part of Co-Q10, SP 15 parts of 3 parts, 0.1 part of epiphysin, 4 parts of collagen, 3 parts of polynucleotides, 6 parts of Phenoxyethanol, 10 parts of peptone and deionized water.
4. Essence according to claim 1, it is characterised in that include the raw material of following parts by weight:12 parts of tea oil, fertility 6 parts of phenol acetic acid esters, 0.7 part of niacinamide, 15 parts of hyaluronic acid, 7 parts of saualane, 2 parts of aspartic acid, 14 parts of glycerine, ursin 3 Part, 8 parts of primrose essential oil, 14 parts of snail secretion filtrate, 8 parts of carbomer, 12 parts of extract solution from aloe, Co-Q10 0.4 part, thread 4 parts of peptide, 0.07 part of epiphysin, 5 parts of collagen, 2 parts of polynucleotides, 7 parts of Phenoxyethanol, 7 parts of peptone and deionized water 20 Part.
5. a kind of preparation method of any Essences of claim 1-4, it is characterised in that comprise the following steps:
A, tocopherol acetate, niacinamide, hyaluronic acid and deionized water are mixed, stirred with 2200-2400r/min rotating speed After 30-50s, 72-78 DEG C is heated to according to 5-8 DEG C/min programming rate, 4-6min is kept, obtains the first premix;
B, tea oil, saualane, glycerine, primrose essential oil, extract solution from aloe, Co-Q10, polynucleotides and peptone are mixed, After 1800-1900r/min rotating speed stirring 2-4min, 55-65 DEG C is heated to according to 3-5 DEG C/min programming rate, is kept 1-2min, obtain the second premix;
C, aspartic acid, ursin, snail secretion filtrate, SP, epiphysin and collagen are mixed, with 1900- After 2000r/min rotating speed stirring 1-3min, 50-60 DEG C is heated to according to 1-3 DEG C/min programming rate, keeps 3-5min, Obtain the 3rd premix;
D, the first premix and the second premix are mixed, at 72-75 DEG C, 12- is stirred under 600-800r/min rotating speed 16min, then successively after the high-pressure homogeneous 12-14min and 8-12MPa low pressure homogeneous 5-7min of 25-35MPa, it is mixed to obtain first Close material;
E, the first compound and the 3rd premix are mixed, stirred under 200-400r/min rotating speed, added while stirring Carbomer and poly(ethylene oxide)polymers, compound is obtained after stirring, as described Essence.
6. preparation method according to claim 5, it is characterised in that in step A, by tocopherol acetate, niacinamide, thoroughly Bright matter acid and deionized water mixing, after 2250-2350r/min rotating speed stirring 35-45s, according to 6-7 DEG C/min heating speed Degree is heated to 72-78 DEG C, keeps 5min, then after the high-pressure homogeneous 12-14min of 25-35MPa, obtain the first premix.
7. preparation method according to claim 5, it is characterised in that in step B, tea oil, saualane, glycerine, the moon are shown in Careless essential oil, extract solution from aloe, Co-Q10, polynucleotides and peptone mixing, 3min is stirred with 1830-1870r/min rotating speed Afterwards, 58-62 DEG C is heated to according to 4 DEG C/min programming rate, keeps 1-2min, then by 8-12MPa low pressure homogeneous 5-7min Afterwards, the second premix is obtained.
8. preparation method according to claim 5, it is characterised in that in step C, by aspartic acid, ursin, snail point Secretion filtrate, SP, epiphysin and collagen mixing, after 1930-1970r/min rotating speed stirring 1-3min, according to 2 DEG C/min programming rate is heated to 53-57 DEG C, 4min is kept, obtains the 3rd premix.
9. preparation method according to claim 5, it is characterised in that in step D, by the first premix and the second premix Mixing, at 73 DEG C, stir 14min under 650-750r/min rotating speed, then successively by the high-pressure homogeneous 12-14min of 30MPa and After 10MPa low pressure homogeneous 5-7min, the first compound is obtained.
10. preparation method according to claim 5, it is characterised in that in step E, carbomer and poly(ethylene oxide)polymers are existed After being stirred under 600-1000r/min rotating speed, add in the first compound and the 3rd premix, compound is cooled to room Temperature simultaneously places ageing 18-22h at 22-24 DEG C, you can obtains the Essence.
CN201710695157.4A 2017-08-15 2017-08-15 A kind of anti-aging, the Essence for promoting cytothesis and preparation method thereof Pending CN107412101A (en)

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CN107823075A (en) * 2017-12-19 2018-03-23 广东德新科技孵化器有限公司 A kind of Essence of anti-wrinkle Firm and preparation method thereof
CN108066215A (en) * 2017-12-27 2018-05-25 国东启 A kind of composition of whitening and anti-aging, the skin care item and preparation method for including it
CN108078901A (en) * 2018-01-30 2018-05-29 付明远 A kind of Essence for adjusting skin water and oil balance, improving microgroove and preparation method thereof
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CN107823075A (en) * 2017-12-19 2018-03-23 广东德新科技孵化器有限公司 A kind of Essence of anti-wrinkle Firm and preparation method thereof
CN108066215A (en) * 2017-12-27 2018-05-25 国东启 A kind of composition of whitening and anti-aging, the skin care item and preparation method for including it
CN108078901A (en) * 2018-01-30 2018-05-29 付明远 A kind of Essence for adjusting skin water and oil balance, improving microgroove and preparation method thereof
CN108852918A (en) * 2018-05-21 2018-11-23 张全兴 A kind of aerolite train of energy skin care item and preparation method thereof
CN108578258A (en) * 2018-05-30 2018-09-28 北京婼薇乐护肤品有限公司 A kind of method capsule essence dew and manufacture capsule essence dew
CN108578258B (en) * 2018-05-30 2022-08-19 北京婼薇乐护肤品有限公司 Capsule essence and method for manufacturing capsule essence
CN108836911A (en) * 2018-08-10 2018-11-20 广州碧雅医疗保健科技有限公司 A kind of compact whitening and moistening skin composition and skin care item containing active ingredient of Chinese herbs
CN108785207A (en) * 2018-08-10 2018-11-13 广州碧雅医疗保健科技有限公司 A kind of anti-aging of the ingredient containing Chinese medicine compound prescription is preserved youthful looks skin care compositions and skin care item
CN110433098A (en) * 2019-06-12 2019-11-12 杨震源 Shin moisturizer and its application of anion, energy element and magnetic effect can be discharged
CN110694054A (en) * 2019-10-25 2020-01-17 张赞红 Mineral concentrate film for promoting hormone secretion, metabolism and circulation and preparation method thereof
CN112370378A (en) * 2020-08-24 2021-02-19 荣鼎(广东)生物科技有限公司 Cosmetic containing guayule troponin stock solution and preparation method thereof
CN112641661A (en) * 2020-09-17 2021-04-13 广西科技大学 Silk fibroin peptide essence and preparation method thereof
CN116120385A (en) * 2023-04-04 2023-05-16 尚诚怡美(成都)生物科技有限公司 Trigonella Foenum nucleic acid with triple helix structure and preparation method and application thereof
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