CN107410642A - It is a kind of to be used to improve kelp cordyceps sinensis pressed candy of male's renal function and preparation method thereof - Google Patents
It is a kind of to be used to improve kelp cordyceps sinensis pressed candy of male's renal function and preparation method thereof Download PDFInfo
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- CN107410642A CN107410642A CN201710412782.3A CN201710412782A CN107410642A CN 107410642 A CN107410642 A CN 107410642A CN 201710412782 A CN201710412782 A CN 201710412782A CN 107410642 A CN107410642 A CN 107410642A
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- 235000009508 confectionery Nutrition 0.000 title claims abstract description 17
- 241000512259 Ascophyllum nodosum Species 0.000 title claims abstract description 14
- 241001248610 Ophiocordyceps sinensis Species 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 230000003907 kidney function Effects 0.000 title claims abstract description 10
- 239000000843 powder Substances 0.000 claims abstract description 54
- 239000000284 extract Substances 0.000 claims abstract description 22
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims abstract description 22
- 241001264174 Cordyceps militaris Species 0.000 claims abstract description 18
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims abstract description 15
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims abstract description 15
- 239000000811 xylitol Substances 0.000 claims abstract description 15
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims abstract description 15
- 229960002675 xylitol Drugs 0.000 claims abstract description 15
- 235000010447 xylitol Nutrition 0.000 claims abstract description 15
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 12
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 12
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 12
- 244000268590 Euryale ferox Species 0.000 claims abstract description 11
- 241000169546 Lycium ruthenicum Species 0.000 claims abstract description 11
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 11
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 11
- 235000013312 flour Nutrition 0.000 claims abstract description 11
- 235000008434 ginseng Nutrition 0.000 claims abstract description 11
- 235000019359 magnesium stearate Nutrition 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 11
- 240000000759 Lepidium meyenii Species 0.000 claims abstract description 10
- 235000000421 Lepidium meyenii Nutrition 0.000 claims abstract description 10
- 235000012902 lepidium meyenii Nutrition 0.000 claims abstract description 10
- 239000000203 mixture Substances 0.000 claims abstract description 7
- 241000208340 Araliaceae Species 0.000 claims description 10
- 239000011122 softwood Substances 0.000 claims description 10
- 239000002245 particle Substances 0.000 claims description 9
- 238000003756 stirring Methods 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 239000004744 fabric Substances 0.000 claims description 6
- 235000020985 whole grains Nutrition 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 3
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 3
- 239000000194 fatty acid Substances 0.000 claims description 3
- 229930195729 fatty acid Natural products 0.000 claims description 3
- 150000004665 fatty acids Chemical class 0.000 claims description 3
- 238000005469 granulation Methods 0.000 claims description 3
- 230000003179 granulation Effects 0.000 claims description 3
- 229910052749 magnesium Inorganic materials 0.000 claims description 3
- 239000011777 magnesium Substances 0.000 claims description 3
- 238000004806 packaging method and process Methods 0.000 claims description 3
- 229910001220 stainless steel Inorganic materials 0.000 claims description 3
- 239000010935 stainless steel Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 2
- 239000007779 soft material Substances 0.000 claims description 2
- 230000001954 sterilising effect Effects 0.000 claims description 2
- 238000005303 weighing Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 11
- DBTMGCOVALSLOR-DEVYUCJPSA-N (2s,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](CO)O[C@H](O)[C@@H]2O)O)O[C@H](CO)[C@H]1O DBTMGCOVALSLOR-DEVYUCJPSA-N 0.000 abstract description 8
- 239000005717 Laminarin Substances 0.000 abstract description 8
- 229920001543 Laminarin Polymers 0.000 abstract description 8
- 210000003734 kidney Anatomy 0.000 abstract description 5
- 230000002929 anti-fatigue Effects 0.000 abstract description 3
- 239000003963 antioxidant agent Substances 0.000 abstract description 3
- 230000003078 antioxidant effect Effects 0.000 abstract description 3
- 235000006708 antioxidants Nutrition 0.000 abstract description 3
- 230000002708 enhancing effect Effects 0.000 abstract description 3
- 235000015097 nutrients Nutrition 0.000 abstract description 3
- 239000004606 Fillers/Extenders Substances 0.000 abstract description 2
- 239000003814 drug Substances 0.000 abstract description 2
- 235000013305 food Nutrition 0.000 abstract description 2
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 description 7
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Substances [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 7
- 208000024891 symptom Diseases 0.000 description 7
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 4
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- 206010061481 Renal injury Diseases 0.000 description 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 2
- 229940109239 creatinine Drugs 0.000 description 2
- 238000003304 gavage Methods 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 206010022437 insomnia Diseases 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 239000013589 supplement Substances 0.000 description 2
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 230000008558 metabolic pathway by substance Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/38—Sucrose-free products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Botany (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The present invention relates to a kind of kelp cordyceps sinensis pressed candy for being used to improve male's renal function and preparation method thereof, belong to medicine and technical field of health care food.Technical scheme is to include the raw material of following parts by weight：5 20 parts of Thallus Laminariae (Thallus Eckloniae) extract, 10 30 parts of Cordyceps militaris powder, 10 30 parts of maca powder, 5 20 parts of ginseng pulverate, 5 10 parts of lycium ruthenicum powder, 5 10 parts of gorgon euryale seed powder, 5 10 parts of yam flour, 1 10 parts of maltodextrin, 1 10 parts of xylitol, 15 parts of magnesium stearate.The present invention mixes Thallus Laminariae (Thallus Eckloniae) extract, Cordyceps militaris powder, laminarin has the bioactivity that anti-oxidant, enhancing was immunized, improved renal function etc., Cordyceps militaris powder can supply energy, it is qualified energy extender, therefore the effect of functional nutrient composition is strengthened, with the antifatigue inferior health health-care effect of kidney tonifying, particularly suitable for man's sub-health population.Trial show that significant effect.
Description
Technical field
The present invention relates to a kind of kelp cordyceps sinensis pressed candy for being used to improve male's renal function and preparation method thereof, belong to medicine
Product and technical field of health care food.
Background technology
With stepping up for present people's living standard, its various life undertaken and social pressures are also got over therewith
Come it is bigger, so as to cause present people to be presented various sub-health states, for example, immunity degradation, insomnia, kidney deficiency, hypertension,
The symptoms such as constipation, therefore the increasingly favor of people is obtained to supplement the nutriment of needed by human body by the method for tonic, so as to
Improve the sub-health state of human body in itself.
The content of the invention
The present invention be to provide it is a kind of be used for improve kelp cordyceps sinensis pressed candy of male's renal function and preparation method thereof, by sea
Band extract, Cordyceps militaris powder mix, and laminarin has the biology that anti-oxidant, enhancing is immune, improves renal function etc. living
Property, Cordyceps militaris powder can supply energy, be qualified energy extender, strengthen the effect of functional nutrient composition, tool
There is the inferior health health-care effect that kidney tonifying is antifatigue, solve above mentioned problem existing for background technology.
The technical scheme is that：
A kind of kelp cordyceps sinensis pressed candy, include the raw material of following parts by weight：Thallus Laminariae (Thallus Eckloniae) extract 5-20 parts, Cordyceps militaris powder 10-30
Part, maca powder 10-30 parts, ginseng pulverate 5-20 parts, lycium ruthenicum powder 5-10 parts, gorgon euryale seed powder 5-10 parts, yam flour 5-10 parts, malt paste
Smart 1-10 parts, xylitol 1-10 parts, magnesium stearate 1-5 parts.
The raw material of the parts by weight, number are as follows：10 parts of Thallus Laminariae (Thallus Eckloniae) extract, 20 parts of Cordyceps militaris powder, 20 parts of maca powder, ginseng
10 parts of powder, 5 parts of lycium ruthenicum powder, 5 parts of gorgon euryale seed powder, 5 parts of yam flour, 10 parts of maltodextrin, 10 parts of xylitol, 5 parts of magnesium stearate.
A kind of preparation method of kelp cordyceps sinensis pressed candy, is comprised the following steps：
（1）Prepare Thallus Laminariae (Thallus Eckloniae) extract；Using prior art preparation method, it is standby to prepare Thallus Laminariae (Thallus Eckloniae) extract；Or bought in market
Thallus Laminariae (Thallus Eckloniae) extract；
（2）Xylitol is placed in pulverizer, pulverizer is opened, xylosic alcohol powder is broken into 80-100 mesh, it is standby；
（3）Weigh stock：Each raw material is weighed by the proportioning of following parts by weight：Step（1）Gained Thallus Laminariae (Thallus Eckloniae) extract 5-20 parts, step
（2）Gained xylitol 1-10 parts, Cordyceps militaris powder 10-30 parts, maca powder 10-30 parts, ginseng pulverate 5-20 parts, lycium ruthenicum powder 5-10
Part, gorgon euryale seed powder 5-10 parts, yam flour 5-10 parts, maltodextrin 1-10 parts, magnesium stearate 1-5 parts；
（4）Prepare softwood：By step（3）The Thallus Laminariae (Thallus Eckloniae) extract, xylitol, maltodextrin for weighing gained are placed in mixer, are opened
Machine stirs, and while stirring plus pure water, stirring 5-10 minutes, prepared softwood reach agglomerating, the tactile i.e. bulk state grabbed, stopped
Add pure water；15-30 minutes are stirred for, obtain softwood；
（5）Granulation：The screen cloth of 12 mesh is mounted on oscillating granulator, oscillating granulator is opened, by step（4）Gained it is soft
Material is added in oscillating granulator and pelletized；
（6）Dry：By step（5）The uniform paving of the particle of gained is dispersed in stainless steel and set off by contrast in disk, starts baking oven, temperature control exists
70-80 °C, dry 4-5 hours；
（7）Whole grain：The screen cloth of 14 mesh is arranged on oscillating granulator, granulator is opened, by step（6）The particle of gained
Add whole grain in oscillating granulator；
（8）It is total mixed：By step（7）The particle of gained is added in Mixers with Multi-direction Movement, then adds step（3）What is weighed is hard
Fatty acid magnesium, Mixers with Multi-direction Movement is opened, mix 15-30 minutes；
（9）Tabletting：Tabletting, tablet forming technique parameter are carried out using tablet press machine：0.2-1 grams, turntable rotating speed 20-30r/min of piece weight, pressure
The newton of piece pressure 30-40 thousand；
（10）Sterilizing, bottling, packaging, you can.
The main component of Thallus Laminariae (Thallus Eckloniae) extract is laminarin, and laminarin is also known as laminarin, algal polysaccharide, is in kelp
Macromolecular polysaccharide material, there is extensive biological activity, can effectively suppress tumour growth, it is anti-oxidant, reduce blood fat, blood
Pressure, especially in terms of renal function is improved, significant effect.Cordyceps militaris has similar bioactivity and its pharmacology to cordyceps sinensis
Effect, its pharmacological function, which is embodied in, alleviates anxiety, uneasiness, improves body substance metabolism and enhancing body immunity etc..
Good effect of the present invention：The present invention mixes Thallus Laminariae (Thallus Eckloniae) extract, Cordyceps militaris powder, and laminarin has antioxygen
Change, strengthen bioactivity that is immune, improving renal function etc., Cordyceps militaris powder can supply energy, be qualified energy supplement
Agent, therefore the effect of functional nutrient composition is strengthened, there is the antifatigue inferior health health-care effect of kidney tonifying；Particularly suitable for man
Property sub-health population, trial show that, significant effect.
Embodiment
Below by way of implementing, the invention will be further described.
Embodiment one：
The kelp cordyceps sinensis pressed candy of the present embodiment, is made up of the raw material of following weight：18 parts of Thallus Laminariae (Thallus Eckloniae) extract, Cordyceps militaris powder 15
Part, 10 parts of lycium ruthenicum powder, 11 parts of gorgon euryale seed powder, 12 parts of yam flour, 9 parts of ginseng pulverate, 11 parts of maca powder, 2 parts of maltodextrin, xylitol
2 parts, 1 part of magnesium stearate.
Preparation method：
（1）Prepare laminarin；
（2）Crush：Xylitol is placed in pulverizer, pulverizer is opened, xylosic alcohol powder is broken into 80-100 mesh, it is standby；
（3）Weigh stock：Each raw material is weighed by the proportioning of following parts by weight：Step（1）18 parts of gained laminarin, step（2）
2 parts of gained xylitol, 15 parts of Cordyceps militaris powder, 10 parts of lycium ruthenicum powder, 11 parts of gorgon euryale seed powder, 12 parts of yam flour, 9 parts of ginseng pulverate, agate card
11 parts of powder, 2 parts of maltodextrin, 1 part of magnesium stearate；
（4）Prepare softwood：By step（3）Weigh gained raw material to be placed in mixer, start stirring, add pure water while stirring, stir
After mixing 5-10 minutes, the addition of pure water is defined with " softwood is grabbed agglomerating, and that touches dissipates ", is stirred 15-30 minutes, is obtained softwood；
（5）Granulation：The screen cloth of 12 mesh is mounted on oscillating granulator, granulator is opened, by step（4）The softwood of gained adds
Pelletized in oscillating granulator；
（6）Dry：By step（5）The uniform paving of the particle of gained is dispersed in stainless steel and set off by contrast in disk, starts baking oven, temperature control exists
70-80 °C, dry 4-5 hours；
（7）Whole grain：The screen cloth of 14 mesh is arranged on oscillating granulator, oscillating granulator is opened, by step（6）Gained
Particle add oscillating granulator in whole grain；
（8）It is total mixed：By step（7）The particle of gained is added in Mixers with Multi-direction Movement, then adds step（3）What is weighed is hard
Fatty acid magnesium, Mixers with Multi-direction Movement is opened, mix 15-30 minutes；
（9）Tabletting：Tablet forming technique parameter：Piece weighs 0.5 gram, turntable rotating speed 20-30r/min, tableting pressure 30-40 thousand newton；
（10）Bottling, packaging, you can.
Instructions of taking is as follows：Three times a day take, oral 4-6 grains every time.
Patient Mr. Li, male, 54 years old, people from Tangshan.Symptoms be general malaise, insobriety, notice not
Concentration, failure of memory, often have a sleepless night, ache all over, weakness of the lower extremities etc..Take the formula gained pressed candy one of embodiment 1
After month, symptom has substantially mitigated.After taking three months, substantially without above-mentioned symptom.
Embodiment two：
The kelp cordyceps sinensis pressed candy of the present embodiment, is made up of the raw material of following weight：20 parts of Thallus Laminariae (Thallus Eckloniae) extract, Cordyceps militaris powder 18
Part, 8 parts of lycium ruthenicum powder, 10 parts of gorgon euryale seed powder, 10 parts of yam flour, 8 parts of ginseng pulverate, 10 parts of maca powder, 2 parts of maltodextrin, xylitol 2
Part, 1 part of magnesium stearate.
Prepare and instructions of taking is the same as embodiment one.
Tan, man, 56 years old, people from Tangshan, Hebei Province.Symptoms are dizzy powerless, insomnia and dreamful sleep, Low Back Pain, night urine
It is more etc., the formula gained pressed candy of embodiment 2 is taken after one month, and symptom has substantially mitigated.After taking three months, symptom is complete
Nothing.
Embodiment three：
The kelp cordyceps sinensis pressed candy of the present embodiment, is made up of the raw material of following weight：17 parts of Thallus Laminariae (Thallus Eckloniae) extract, Cordyceps militaris powder 17
Part, 10 parts of lycium ruthenicum powder, 10 parts of gorgon euryale seed powder, 10 parts of yam flour, 10 parts of maca powder, 10 parts of ginseng pulverate, 2 parts of maltodextrin, xylose
3 parts of alcohol, 1 part of magnesium stearate.
Preparation method is the same as embodiment one.
Experimental animal efficiency assay
The structure of mouse renal injury model：
Cleaning grade（SPF）Female BAl BIc/c mouse, 18 ± 2g of body weight, 3 groups are randomly divided into, every group 10, respectively normal control
Group, cis-platinum model group, cis-platinum model administration group.Mouse is adapted to after feeding 1 week, and fasting can't help water 15 hours.Model group is using single
Secondary intraperitoneal injection cis-platinum 15mg/Kg inducing mouse renal injury models.Administration group continuous gavage embodiment 3 prepares institute after model success
The pressed candy 400mg/Kg BW obtained 21 days, control group and model group while gavage physiological saline.1 is small after last time is administered
When, using intraocular corner of the eyes venous blood sampling, detect creatinine and urea nitrogen.Blood sample is placed in 4 DEG C, 3000rpm of refrigerated centrifuge, centrifuged
10min, supernatant serum is taken to be detected.
Testing result is as follows：
| Group | Creatinine μm ol/L | Urea nitrogen mmol/L |
| Normal group | 23.54±0.98 | 7.61 ±1.21 |
| Cis-platinum model group | 57.31±3.24 | 15.26±2.64 |
| Cis-platinum model administration group | 28.65±1.27 | 8.03 ±2.04 |
Cis-platinum model administration group is can be seen that from the result of above table to contrast with cis-platinum model group, its blood flesh is matched somebody with somebody and urea nitrogen
Drop to normal level or so, it is seen that this pressed candy has good therapeutic effect to mouse injury of kidney.
Claims (3)
1. a kind of kelp cordyceps sinensis pressed candy for being used to improve male's renal function, it is characterised in that include the original of following parts by weight
Material：Thallus Laminariae (Thallus Eckloniae) extract 5-20 parts, Cordyceps militaris powder 10-30 parts, maca powder 10-30 parts, ginseng pulverate 5-20 parts, lycium ruthenicum powder 5-10
Part, gorgon euryale seed powder 5-10 parts, yam flour 5-10 parts, maltodextrin 1-10 parts, xylitol 1-10 parts, magnesium stearate 1-5 parts.
2. a kind of kelp cordyceps sinensis pressed candy according to claim 1, it is characterised in that the raw material of the parts by weight, number
It is as follows：10 parts of Thallus Laminariae (Thallus Eckloniae) extract, 20 parts of Cordyceps militaris powder, 20 parts of maca powder, 10 parts of ginseng pulverate, 5 parts of lycium ruthenicum powder, 5 parts of gorgon euryale seed powder,
5 parts of yam flour, 10 parts of maltodextrin, 10 parts of xylitol, 5 parts of magnesium stearate.
3. a kind of preparation method of kelp cordyceps sinensis pressed candy, it is characterised in that comprise the following steps：
（1）Prepare Thallus Laminariae (Thallus Eckloniae) extract；Using prior art preparation method, it is standby to prepare Thallus Laminariae (Thallus Eckloniae) extract；Or bought in market
Thallus Laminariae (Thallus Eckloniae) extract；
（2）Xylitol is placed in pulverizer, pulverizer is opened, xylosic alcohol powder is broken into 80-100 mesh, it is standby；
（3）Weigh stock：Each raw material is weighed by the proportioning of following parts by weight：Step（1）Gained Thallus Laminariae (Thallus Eckloniae) extract 5-20 parts, step
（2）Gained xylitol 1-10 parts, Cordyceps militaris powder 10-30 parts, maca powder 10-30 parts, ginseng pulverate 5-20 parts, lycium ruthenicum powder 5-10
Part, gorgon euryale seed powder 5-10 parts, yam flour 5-10 parts, maltodextrin 1-10 parts, magnesium stearate 1-5 parts；
（4）Prepare softwood：By step（3）The Thallus Laminariae (Thallus Eckloniae) extract, xylitol, maltodextrin for weighing gained are placed in mixer, are opened
Machine stirs, and while stirring plus pure water, stirring 5-10 minutes, prepared softwood reach agglomerating, the tactile i.e. bulk state grabbed, stopped
Add pure water；15-30 minutes are stirred for, obtain softwood；
（5）Granulation：The screen cloth of 12 mesh is mounted on oscillating granulator, oscillating granulator is opened, by step（4）Gained it is soft
Material is added in oscillating granulator and pelletized；
（6）Dry：By step（5）The uniform paving of the particle of gained is dispersed in stainless steel and set off by contrast in disk, starts baking oven, temperature control exists
70-80 °C, dry 4-5 hours；
（7）Whole grain：The screen cloth of 14 mesh is arranged on oscillating granulator, granulator is opened, by step（6）The particle of gained
Add whole grain in oscillating granulator；
（8）It is total mixed：By step（7）The particle of gained is added in Mixers with Multi-direction Movement, then adds step（3）What is weighed is hard
Fatty acid magnesium, Mixers with Multi-direction Movement is opened, mix 15-30 minutes；
（9）Tabletting：Tabletting, tablet forming technique parameter are carried out using tablet press machine：0.2-1 grams, turntable rotating speed 20-30r/min of piece weight, pressure
The newton of piece pressure 30-40 thousand；
（10）Sterilizing, bottling, packaging, you can.
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| CN201710412782.3A CN107410642A (en) | 2017-06-05 | 2017-06-05 | It is a kind of to be used to improve kelp cordyceps sinensis pressed candy of male's renal function and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109965067A (en) * | 2017-12-27 | 2019-07-05 | 上海梓惜生物技术有限公司 | A kind of Noni puree Cordyceps militaris pressed candy and preparation method thereof |
| CN111280283A (en) * | 2018-12-10 | 2020-06-16 | 广东卓康伽美医疗科技有限公司 | Pressed candy with kidney cell repairing effect and preparation method thereof |
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| CN103860604A (en) * | 2013-12-13 | 2014-06-18 | 青岛昆布生物工程有限公司 | Compound tablet containing kelp extract and cordyceps militaris |
| CN104056002A (en) * | 2013-03-22 | 2014-09-24 | 王良平 | Traditional Chinese medicine composition capable of tonifying kidney |
| CN105613917A (en) * | 2014-12-01 | 2016-06-01 | 哈尔滨墨医生物技术有限公司 | Kidney supplementing and fatigue preventing maca compound tableting candy and preparation method thereof |
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| CN104056002A (en) * | 2013-03-22 | 2014-09-24 | 王良平 | Traditional Chinese medicine composition capable of tonifying kidney |
| CN103860604A (en) * | 2013-12-13 | 2014-06-18 | 青岛昆布生物工程有限公司 | Compound tablet containing kelp extract and cordyceps militaris |
| CN105613917A (en) * | 2014-12-01 | 2016-06-01 | 哈尔滨墨医生物技术有限公司 | Kidney supplementing and fatigue preventing maca compound tableting candy and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109965067A (en) * | 2017-12-27 | 2019-07-05 | 上海梓惜生物技术有限公司 | A kind of Noni puree Cordyceps militaris pressed candy and preparation method thereof |
| CN111280283A (en) * | 2018-12-10 | 2020-06-16 | 广东卓康伽美医疗科技有限公司 | Pressed candy with kidney cell repairing effect and preparation method thereof |
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Application publication date: 20171201 |