CN107375798A - A kind of anti-inflammation and sterilization tablet and preparation method thereof - Google Patents

A kind of anti-inflammation and sterilization tablet and preparation method thereof Download PDF

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Publication number
CN107375798A
CN107375798A CN201710648268.XA CN201710648268A CN107375798A CN 107375798 A CN107375798 A CN 107375798A CN 201710648268 A CN201710648268 A CN 201710648268A CN 107375798 A CN107375798 A CN 107375798A
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Prior art keywords
parts
inflammation
scouring rush
borneol
stemona
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张永才
李斯
关照利
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Liaoning Pico Biotechnology Co Ltd
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Liaoning Pico Biotechnology Co Ltd
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Priority to CN201710648268.XA priority Critical patent/CN107375798A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
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    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K9/2013Organic compounds, e.g. phospholipids, fats
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones

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Abstract

The invention discloses a kind of anti-inflammation and sterilization tablet, including following component:Kuh-seng, golden cypress, the tuber of stemona, felwort, scouring rush, alumen, Asian puccoon, frutus cnidii, the fruit of summer cypress, scouring rush, oldenlandia diffusa, peppermint, borneol, Radix Angelicae Sinensis, centella, great Hua cactuses, aloe, filler, lubricant.The drug ingedient formula of the present invention is pure natural, it is non-stimulated gently to sterilize, and avoiding producing human body toxic side effect has the effect of alleviating privates itch, going to eliminate the unusual smell, persistently sterilize.

Description

A kind of anti-inflammation and sterilization tablet and preparation method thereof
Technical field
The present invention relates to a kind of anti-inflammation and sterilization technical field of pharmaceuticals, more particularly to a kind of anti-inflammation and sterilization tablet and its preparation side Method, suitable for preventing or treating the various gynecological diseases directly or indirectly infected.
Background technology
Due to the appearance of sanltary towel, brought conveniently to numerous Mies, but not advising due to manufacturer production program Model, raw material disinfection measure imperfection, factory building are simple and crude, technique simplifies, and cause the sanitary napkin inherently object that carries disease germs, The infection chance of user is caused to increase, numerous women have suffered from infectious diseases, or even infect other severe infections disease, make Into the infection that crosses one another, serious threat numerous women and its physical and mental health of spouse, or even leaves irreversible consequence, such as The disease such as severe infections, infertile.
With social progress, sanitary napkin has greatly facilitated the daily life of women, for having prevented and treated various menstrual symptoms Sanitary towels through having invented all size model, there is property.Special medicaments sanitary napkin is according to women menstrual period Physiology and pathological characters, pick natural Chinese herbal medicines, through scientific allocation, the curative effect of anti-inflammation, antalgic can be played;Will It is various that there are the Chinese and western drugses for killing and suppressing the effects such as pathogenic microorganism, anti-inflammatory analgetic to carry out prescription, play prevention of diseae Effect, at the same can be obviously improved female menstrual period is infected caused by pruritus vulvue, cusalgia, the discomfort such as secretion is more, smell is stench Symptom.
The content of the invention
It is an object of the invention to provide a kind of formula it is natural, gently sterilize non-stimulated anti-inflammation and sterilization tablet and its preparation Method, avoiding producing human body toxic side effect has the effect of alleviating privates itch, going to eliminate the unusual smell, persistently sterilize.
In order to realize above-mentioned technical purpose, reach above-mentioned technique effect, the present invention is achieved through the following technical solutions:
A kind of anti-inflammation and sterilization tablet, including following component:Kuh-seng, golden cypress, the tuber of stemona, felwort, scouring rush, alumen, Asian puccoon, snake Machine tool, the fruit of summer cypress, scouring rush, oldenlandia diffusa, peppermint, borneol, Radix Angelicae Sinensis, centella, great Hua cactuses, aloe, filler, lubrication Agent.
A kind of anti-inflammation and sterilization tablet, component proportion in parts by weight are:3~10 parts of kuh-seng, 8~20 parts of golden cypress, the tuber of stemona 5 ~16 parts, 5~20 parts of felwort, 4~18 parts of scouring rush, 3~12 parts of alumen, 6~20 parts of Asian puccoon, 2~15 parts of frutus cnidii, the fruit of summer cypress 5~25 parts, 7~19 parts of scouring rush, 8~26 parts of oldenlandia diffusa, 9~24 parts of peppermint, 3~8 parts of borneol, 5~15 parts of Radix Angelicae Sinensis, accumulated snow 6~22 parts of grass, 10~25 parts of great Hua cactuses, 3~18 parts of aloe, 5~20 parts of filler, 10~25 parts of lubricant..
Preferably, a kind of anti-inflammation and sterilization tablet, component proportion in parts by weight are:5 parts of kuh-seng, 15 parts of golden cypress, the tuber of stemona 10 parts, 15 parts of felwort, 8 parts of scouring rush, 5 parts of alumen, 9 parts of Asian puccoon, 12 parts of frutus cnidii, 18 parts of the fruit of summer cypress, 16 parts of scouring rush, long-noded pit viper 20 parts of tongue grass, 16 parts of peppermint, 6 parts of borneol, 12 parts of Radix Angelicae Sinensis, 11 parts of centella, 17 parts of great Hua cactuses, 15 parts of aloe, filler 14 parts, 16 parts of lubricant.
A kind of method for preparing above-mentioned anti-inflammation and sterilization tablet, comprises the following steps:
Step 1:By kuh-seng, golden cypress, the tuber of stemona, felwort, scouring rush, alumen, Asian puccoon, frutus cnidii, the fruit of summer cypress, scouring rush, white flower HERBA HEDYOTIS DIFFUSAE, peppermint, borneol, Radix Angelicae Sinensis, centella, great Hua cactuses, aloe are stirred into powder mixing after claying into power respectively Thing, it is standby;
Step 2:Ethanol is added into mixture of powders, is soaked at least 24 hours, by being extracted after distilling, filtering Liquid;
Step 3:Borneol will be added in the extract solution, borneol is heated to together with extract solution and is dissolved as to filtering, acquisition Drug extract, drug extract is put into baking oven acquisition medical solid is dried;
Step 4:It is pulverized and mixed with filler, lubricant, anti-caking agent after medical solid is crushed, dries again, crosses 60 ~100 mesh sieves, direct pressed powder after piece weight is determined, obtains medicinal tablet.
Further, the filler is lactose, glucose, sucrose, mannitol, sorbierite, starch or microcrystalline cellulose In one kind or any two or more combination.
Further, the lubricant is magnesium stearate, calcium stearate, zinc stearate, talcum powder, polyethylene glycol and micro- One kind of powder silica gel or any two or more combination.
The present invention adheres to Traditional Chinese Medicine culture, selecting can kill and press down according to the physiology and pathological characters of women menstrual period Pathogenic microorganism processed, with anti-inflammatory analgetic, eliminating dampness is antipruritic, removes dampness by means of aromatics, the natural Chinese herbal medicines of refrigerant skin, is rationally matched somebody with somebody Close, it is gentle to obtain nature and flavor, and there is bactericidal antiphlogistic, removing dampness to stop itchin to act on, and does not have irritant pure natural Chinese herbal medicine thing to add to skin Add agent.
In the presence of body temperature and moisture, through skin, successively permeate, can effectively prevent vagina caused by various infection The illnesss such as inflammation, cervical erosion.
Show by probation:Produced after use without any abnormal sensory and peculiar smell, can help to original inflammation recovery from illness and Prevent women menstruation infection and therefrom caused various diseases.
The beneficial effects of the invention are as follows:
1st, drug ingedient of the invention has disinfection, antipruritic, antianaphylactic effect, can effectively prevent female menstrual period sense Dye and thus caused various diseases, are prevented and its spouse's cross-infection.
2nd, present invention uses the medicinal powder of ultra-fine grain, active ingredient can connect rapidly at suitable temperature and damp condition Continuous release, the rapid Prolonged absorption of skin energy, substantially increases prevention and treatment effect.
3rd, drug ingedient of the invention formula is pure natural, it is non-stimulated gently to sterilize, and avoids producing human body toxic side effect tool There is the effect of alleviating privates itch, going to eliminate the unusual smell, persistently sterilize.
Embodiment
To enable the purpose of the present invention, feature, advantage more obvious and understandable, below in the embodiment of the present invention Technical scheme is clearly and completely described, it is clear that and the embodiments described below are only part of the embodiment of the present invention, And not all embodiments.Based on the embodiment in the present invention, every other embodiment that those skilled in the art is obtained, all Belong to the scope of protection of the invention.
Embodiment 1
A kind of anti-inflammation and sterilization tablet, component proportion in parts by weight are:Kuh-seng 5g, golden cypress 15g, tuber of stemona 10g, felwort 15g, scouring rush 8g, alumen 5g, Asian puccoon 9g, frutus cnidii 12g, fruit of summer cypress 18g, scouring rush 16g, oldenlandia diffusa 20g, peppermint 16g, ice Piece 6g, Radix Angelicae Sinensis 12g, centella 11g, great Hua cactus 17g, aloe 15g, mannitol 14g, magnesium stearate 16g.
A kind of method for preparing above-mentioned anti-inflammation and sterilization tablet, comprises the following steps:
Step 1:According to above-mentioned weight weighing by kuh-seng, golden cypress, the tuber of stemona, felwort, scouring rush, alumen, Asian puccoon, frutus cnidii, The fruit of summer cypress, scouring rush, oldenlandia diffusa, peppermint, borneol, Radix Angelicae Sinensis, centella, great Hua cactuses, aloe are dried clay into power respectively After be stirred into mixture of powders, it is standby;
Step 2:400ml ethanol is added into mixture of powders, soaks at least 24 hours, extract solution is obtained after filtering;
Step 3:6g borneols will be added in the extract solution, borneol is heated to together with extract solution and is dissolved as to filtering, obtain Drug extract is obtained, drug extract vacuum decompression is distilled and obtains medical solid;
Step 4:With 14g mannitol, 16g magnesium stearates after medical solid is crushed, dry again, cross 60 mesh sieves, it is determined that Direct pressed powder after piece weight, obtains medicinal tablet.
Embodiment 2
Kuh-seng 3~10, golden cypress 8g, tuber of stemona 5g, felwort 5g, scouring rush 4g, alumen 3g, Asian puccoon 6g, frutus cnidii 2g, the fruit of summer cypress 5g, scouring rush 7g, oldenlandia diffusa 8g, peppermint 9g, borneol 3g, Radix Angelicae Sinensis 5g, centella 6g, great Hua cactus 10g, aloe 3g, sugarcane Sugared 5g, calcium stearate 10g.
A kind of method for preparing above-mentioned anti-inflammation and sterilization tablet, comprises the following steps:
Step 1:According to above-mentioned weight weighing by kuh-seng, golden cypress, the tuber of stemona, felwort, scouring rush, alumen, Asian puccoon, frutus cnidii, The fruit of summer cypress, scouring rush, oldenlandia diffusa, peppermint, borneol, Radix Angelicae Sinensis, centella, great Hua cactuses, aloe are dried clay into power respectively After be stirred into mixture of powders, it is standby;
Step 2:450ml ethanol is added into mixture of powders, soaks at least 28 hours, extract solution is obtained after filtering;
Step 3:3g borneols will be added in the extract solution, borneol is heated to together with extract solution and is dissolved as to filtering, obtain Drug extract is obtained, drug extract vacuum decompression is distilled and obtains medical solid;
Step 4:With 5g sucrose, 10g calcium stearates after medical solid is crushed, dry again, cross 100 mesh sieves, determine piece Direct pressed powder after weight, obtain medicinal tablet.
Embodiment 3
A kind of anti-inflammation and sterilization tablet, component proportion in parts by weight are:Kuh-seng 10g, golden cypress 20g, tuber of stemona 16g, rough gentian Careless 20g, scouring rush 18g, alumen 12g, Asian puccoon 20g, frutus cnidii 15g, fruit of summer cypress 25g, scouring rush 19g, oldenlandia diffusa 26g, peppermint 24g, borneol 8g, Radix Angelicae Sinensis 15g, centella 22g, great Hua cactus 25g, aloe 18g, lactose 20g, zinc stearate 25g.
A kind of method for preparing above-mentioned anti-inflammation and sterilization tablet, comprises the following steps:
Step 1:According to above-mentioned weight weighing by kuh-seng, golden cypress, the tuber of stemona, felwort, scouring rush, alumen, Asian puccoon, frutus cnidii, The fruit of summer cypress, scouring rush, oldenlandia diffusa, peppermint, borneol, Radix Angelicae Sinensis, centella, great Hua cactuses, aloe are dried clay into power respectively After be stirred into mixture of powders, it is standby;
Step 2:500ml ethanol is added into mixture of powders, soaks at least 28 hours, extract solution is obtained after filtering;
Step 3:8g borneols will be added in the extract solution, borneol is heated to together with extract solution and is dissolved as to filtering, obtain Drug extract is obtained, drug extract vacuum decompression is distilled and obtains medical solid;
Step 4:With 5g lactose, 10g zinc stearates after medical solid is crushed, dry again, cross 100 mesh sieves, determine piece Direct pressed powder after weight, obtain medicinal tablet.
Embodiment 4
A kind of anti-inflammation and sterilization tablet, component proportion in parts by weight are:Kuh-seng 6g, golden cypress 15g, tuber of stemona 12g, felwort 18g, scouring rush 10g, alumen 7g, Asian puccoon 11g, frutus cnidii 4g, fruit of summer cypress 12g, scouring rush 15g, oldenlandia diffusa 16g, peppermint 18g, Borneol 8g, Radix Angelicae Sinensis 5g, centella 13g, great Hua cactus 15g, aloe 16g, starch 11g, polyethylene glycol 16g.
A kind of method for preparing above-mentioned anti-inflammation and sterilization tablet, comprises the following steps:
Step 1:According to above-mentioned weight weighing by kuh-seng, golden cypress, the tuber of stemona, felwort, scouring rush, alumen, Asian puccoon, frutus cnidii, The fruit of summer cypress, scouring rush, oldenlandia diffusa, peppermint, borneol, Radix Angelicae Sinensis, centella, great Hua cactuses, aloe are dried clay into power respectively After be stirred into mixture of powders, it is standby;
Step 2:550ml ethanol is added into mixture of powders, soaks at least 36 hours, extract solution is obtained after filtering;
Step 3:8g borneols will be added in the extract solution, borneol is heated to together with extract solution and is dissolved as to filtering, obtain Drug extract is obtained, drug extract vacuum decompression is distilled and obtains medical solid;
Step 4:With 11g starch, 16g polyethylene glycol after medical solid is crushed, dry again, cross 80 mesh sieves, determine piece Direct pressed powder after weight, obtain medicinal tablet.
Embodiment 4
A kind of anti-inflammation and sterilization tablet, component proportion in parts by weight are:Kuh-seng 5g, golden cypress 12g, tuber of stemona 6g, felwort 11g, scouring rush 8g, alumen 10g, Asian puccoon 9g, frutus cnidii 12g, fruit of summer cypress 15g, scouring rush 10g, oldenlandia diffusa 16g, peppermint 18g, Borneol 6g, Radix Angelicae Sinensis 11g, centella 17g, great Hua cactus 13g, aloe 11g, microcrystalline cellulose 13g, superfine silica gel powder 14g.
A kind of method for preparing above-mentioned anti-inflammation and sterilization tablet, comprises the following steps:
Step 1:According to above-mentioned weight weighing by kuh-seng, golden cypress, the tuber of stemona, felwort, scouring rush, alumen, Asian puccoon, frutus cnidii, The fruit of summer cypress, scouring rush, oldenlandia diffusa, peppermint, borneol, Radix Angelicae Sinensis, centella, great Hua cactuses, aloe are dried clay into power respectively After be stirred into mixture of powders, it is standby;
Step 2:450ml ethanol is added into mixture of powders, soaks at least 36 hours, extract solution is obtained after filtering;
Step 3:8g borneols will be added in the extract solution, borneol is heated to together with extract solution and is dissolved as to filtering, obtain Drug extract is obtained, drug extract vacuum decompression is distilled and obtains medical solid;
Step 4:With 11g microcrystalline celluloses, 16g superfine silica gel powders after medical solid is crushed, dry again, cross 60 mesh sieves, Direct pressed powder after determining piece again, obtains medicinal tablet.
Although the above-mentioned embodiment to the present invention is described, not to the limit of the scope of the present invention System, one of ordinary skill in the art should be understood that on the basis of technical scheme those skilled in the art need not pay Go out various modifications that creative work can make or deformation is still within the scope of the present invention.

Claims (6)

1. a kind of anti-inflammation and sterilization tablet, it is characterised in that including following component:It is kuh-seng, golden cypress, the tuber of stemona, felwort, scouring rush, withered Alum, Asian puccoon, frutus cnidii, the fruit of summer cypress, scouring rush, oldenlandia diffusa, peppermint, borneol, Radix Angelicae Sinensis, centella, great Hua cactuses, aloe, Filler, lubricant.
2. anti-inflammation and sterilization tablet according to claim 1, it is characterised in that component proportion in parts by weight is:Kuh-seng 3 ~10 parts, 8~20 parts of golden cypress, 5~16 parts of the tuber of stemona, 5~20 parts of felwort, 4~18 parts of scouring rush, 3~12 parts of alumen, Asian puccoon 6~ 20 parts, 2~15 parts of frutus cnidii, 5~25 parts of the fruit of summer cypress, 7~19 parts of scouring rush, 8~26 parts of oldenlandia diffusa, 9~24 parts of peppermint, ice 3~8 parts of piece, 5~15 parts of Radix Angelicae Sinensis, 6~22 parts of centella, 10~25 parts of great Hua cactuses, 3~18 parts of aloe, filler 5~20 Part, 10~25 parts of lubricant.
3. anti-inflammation and sterilization tablet according to claim 1, it is characterised in that component proportion in parts by weight is:Kuh-seng 5 Part, 15 parts of golden cypress, 10 parts of the tuber of stemona, 15 parts of felwort, 8 parts of scouring rush, 5 parts of alumen, 9 parts of Asian puccoon, 12 parts of frutus cnidii, the fruit of summer cypress 18 Part, 16 parts of scouring rush, 20 parts of oldenlandia diffusa, 16 parts of peppermint, 6 parts of borneol, 12 parts of Radix Angelicae Sinensis, 11 parts of centella, great Hua cactuses 17 Part, 15 parts of aloe, 14 parts of filler, 16 parts of lubricant.
4. anti-inflammation and sterilization tablet according to claim 1, it is characterised in that the filler is lactose, glucose, sugarcane One kind or any two or more combination in sugar, mannitol, sorbierite, starch or microcrystalline cellulose.
5. anti-inflammation and sterilization tablet according to claim 1, it is characterised in that the lubricant is magnesium stearate, stearic acid Calcium, zinc stearate, talcum powder, one kind of polyethylene glycol and superfine silica gel powder or any two or more combination.
A kind of 6. method for preparing anti-inflammation and sterilization tablet according to claim 1, it is characterised in that comprise the following steps:
Step 1:By kuh-seng, golden cypress, the tuber of stemona, felwort, scouring rush, alumen, Asian puccoon, frutus cnidii, the fruit of summer cypress, scouring rush, oldenlandia Grass, peppermint, borneol, Radix Angelicae Sinensis, centella, great Hua cactuses, aloe are stirred into mixture of powders after claying into power respectively, standby With;
Step 2:Ethanol is added into mixture of powders, is soaked at least 24 hours, by obtaining extract solution after distilling, filtering;
Step 3:Borneol will be added in the extract solution, borneol is heated to together with extract solution and is dissolved as to filtering, acquisition medicine Extract solution, drug extract is put into baking oven acquisition medical solid is dried;
Step 4:It is pulverized and mixed with filler, lubricant, anti-caking agent after medical solid is crushed, dries again, crosses 60~100 Mesh sieve, direct pressed powder after piece weight is determined, obtains medicinal tablet.
CN201710648268.XA 2017-08-01 2017-08-01 A kind of anti-inflammation and sterilization tablet and preparation method thereof Pending CN107375798A (en)

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Application publication date: 20171124