CN107375550A - 一种治疗鲟鱼肠炎病的中草药及其制备方法 - Google Patents

一种治疗鲟鱼肠炎病的中草药及其制备方法 Download PDF

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CN107375550A
CN107375550A CN201710659985.2A CN201710659985A CN107375550A CN 107375550 A CN107375550 A CN 107375550A CN 201710659985 A CN201710659985 A CN 201710659985A CN 107375550 A CN107375550 A CN 107375550A
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sturgeon
radix
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汪晓鸿
左宜
章星明
周洵
柴继芳
俞爱萍
李宝忠
夏守义
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Jingxian County Anhui Feng Feng Aquatic Science And Technology Co Ltd
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Abstract

本发明公开了一种治疗鲟鱼肠炎病的中草药，其原料包括：大蒜素、板蓝根、金银花、大黄、黄柏、五倍子、大青叶、野菊花。其原料还包括：黄芩、龙葵、生姜、石榴皮、赤芍、山楂、麦芽、玄明粉、陈皮、厚朴、甘草、枳实。本发明提出的治疗鲟鱼肠炎病的中草药及其制备方法，发挥协同增效的作用，能显著增强鲟鱼机体免疫力，增强抗病力，杀灭抑制肠炎病病原体肠型点状气单胞菌，而且可代谢完全，安全无副作用。

Description

一种治疗鲟鱼肠炎病的中草药及其制备方法
技术领域
本发明涉及水产中药技术领域，尤其涉及一种治疗鲟鱼肠炎病的中草药及其制备方法。
背景技术
肠炎病是由肠型点状产气单胞菌感染引起的细菌性肠炎。其病原存在于天然水体及水底淤泥之中，健康鱼肠道也常有此菌，当水质恶化、溶氧低、饲料变质等引起鱼体抵抗力下降时，常暴发本病。此病的原体为肠型点状气单胞菌，为条件致病菌。在鲟鱼的全部养殖进程中肠道内都存在此类病菌。但在健康的鲟鱼体中，该菌种没有占优势，不会引发疾病。
患病鱼游动缓慢，食欲减退，严重者可见肛门红肿，轻压腹部有黄色粘液流出。镜检后可见肠内部无食物，仅有黄色粘液。
发明内容
基于背景技术存在的技术问题，本发明提出了一种治疗鲟鱼肠炎病的中草药及其制备方法，发挥协同增效的作用，能显著增强鲟鱼机体免疫力，增强抗病力，杀灭抑制肠炎病病原体肠型点状气单胞菌，而且可代谢完全，安全无副作用。
本发明提出的一种治疗鲟鱼肠炎病的中草药，其原料包括：大蒜素、板蓝根、金银花、大黄、黄柏、五倍子、大青叶、野菊花。
优选地，其原料按重量份包括：大蒜素50-80份，板蓝根200-300份，金银花50-100份，大黄50-80份，黄柏30-50份，五倍子50-70份，大青叶100-120份，野菊花50-100份。
优选地，其原料还包括：黄芩、龙葵、生姜、石榴皮、赤芍、山楂、麦芽、玄明粉、陈皮、厚朴、甘草、枳实。
优选地，其原料按重量份包括：大蒜素50-80份，板蓝根200-300份，金银花50-100份，大黄50-80份，黄柏30-50份，五倍子50-70份，大青叶100-120份，野菊花50-100份，黄芩40-50份，龙葵15-35份，生姜10-30份，石榴皮4-18份，赤芍8-16份，山楂15-35份，麦芽10-18份，玄明粉1-6份，陈皮10-20份，厚朴14-22份，甘草15-25份，枳实11-17份。
大蒜素，具有抑菌杀菌，诱食增食，解毒保健，防霉驱虫，改善肉质，对鱼、虾、鳖因各种感染引起的烂腮、赤皮、肠炎、出血等疾病的治疗有特效。
板蓝根，味苦，性寒，归胃经、肝经。能清热解毒，凉血利咽。用于温毒发斑，舌绛紫暗，痄腮，喉痹，烂喉丹痧，大头瘟疫，丹毒，痈肿。
金银花，味甘，性寒。归肺、心、胃经。能清热解毒，凉散风热。用于痈肿疔疮，喉痹，丹毒，热血毒痢，风热感冒，温病发热。
大黄，味苦，性寒，归胃经、肝经、大肠经。能泻实热，破积滞，行瘀血。主治实热便秘，食积停滞，腹痛，急性阑尾炎，急性传染性肝炎，血瘀经闭，牙痛，衄血，急性结膜炎；外用治烧烫伤，化脓性皮肤病，痈肿疮疡。
黄柏，味苦，性寒。归肾、膀胱、大肠经。能清热燥湿；泻火解毒。主治湿热痢疾、泄泻、黄疸；梦遗、淋浊、带下；骨蒸劳热；以及口舌生疮；目赤肿痛；痈疽疮毒；皮肤湿疹。
五倍子，味酸，性平，归肺经、肾经、大肠经。能敛肺，止汗，涩肠，固精，止血，解毒。主肺虚久咳，自汗盗汗，久痢久泻，脱肛，遗精，白浊，各种出血，痈肿疮疖。
大青叶，味苦，性寒，归胃经、心经。能清热解毒，凉血消斑。用于温邪入营，高热神昏，发斑发疹，黄疸，热痢，痄腮，喉痹，丹毒，痈肿。
野菊花，味辛、苦，性微寒，归肺、肝经。能清热解毒，疏风平肝。主治疔疮；痈疽；丹毒；湿疹；皮炎；风热感冒；咽喉肿痛；高血压病。
黄芩，味苦，性寒。归肺、胆、脾、大肠、小肠经。能清热燥湿，泻火解毒，止血，安胎。用于湿温、暑温胸闷呕恶，湿热痞满，泻痢，黄疸，肺热咳嗽，高热烦渴，血热吐衄，痈肿疮毒，胎动不安。
龙葵，味苦，性寒。能清热解毒；活血消肿。主治疔疮；痈肿；丹毒；跌打扭伤；慢性气管炎；肾炎水肿
生姜，味辛，性微温，归肺、脾、胃经。能发汗解表，温中止呕，温肺止咳，解鱼蟹毒，解药毒。
石榴皮，味酸、涩，性温，归大肠经。能涩肠止泻，止血，驱虫。用于久泻，久痢，便血，脱肛，崩漏，白带，虫积腹痛。
赤芍，味苦，微性寒。归肝经。能清热凉血，散瘀止痛。用于温毒发斑，吐血衄血，目赤肿痛，肝郁胁痛，经闭痛经，症瘕腹痛，跌扑损伤，痈肿疮疡。
山楂，味酸、甘，性微温。归胃经、脾经、肝经。能开胃消食、化滞消积、活血散瘀、化痰行气。用于肉食滞积、症瘕积聚、腹胀痞满、瘀阻腹痛、痰饮、泄泻、肠风下血等。
麦芽，味甘，性平，能消食，和中，下气。主治食积不消，脘腹胀满，食欲不振，呕吐泄泻，乳胀不消。
玄明粉，味辛、咸，性寒，归胃、心、肺、大肠经。能泻热通便；软坚散结；清热解毒；清肺解暑；消积和胃。主治实热积滞；大便不通；目赤肿痛；咽肿口疮；痈疽肿毒。
陈皮，味辛、苦，性温，归肺经、脾经。能理气健脾，燥湿化痰。用于胸脘胀满，食少吐泻，咳嗽痰多。
厚朴，味苦、辛，性温。归脾、胃、肺、大肠经。能燥湿消痰，下气除满。用于燥湿消痰，下气除满。用于湿滞伤中，脘痞吐泻，食积气滞，腹胀便秘，痰饮喘咳。
甘草，性平，味甘，归十二经。能补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
枳实，味苦、辛；性寒。归脾、胃、肝、心经。能积滞内停；痞满胀痛；大便秘结；泻痢后重；结胸；胃下垂；子宫脱垂；脱肛。
本发明还提出上述治疗鲟鱼肠炎病的中草药制备方法，将原料混合粉碎后，加水煎煮2-3h，过滤，取煎煮液冷却即得。
本发明采用大蒜素、板蓝根、金银花、大黄、黄柏、五倍子、大青叶、野菊花配合作为主料，具有抑菌杀菌、诱食增食、解毒保健的效果，能有效抑制鲟鱼体中肠型点状气单胞菌繁殖；再采用黄芩、龙葵、生姜、石榴皮、赤芍、山楂、麦芽、玄明粉、陈皮、厚朴、甘草、枳实配合主料，具有消食下气、开胃宽敞的功效，增强鱼自身免疫力及抗病力，有效降低鱼病死率，临床给药简便，适合鱼体给药，节省人力物力。上述诸药合用，发挥协同增效的作用，能显著增强鲟鱼机体免疫力，增强抗病力，杀灭抑制肠炎病病原体，而且可代谢完全，安全无副作用。
具体实施方式
下面，通过具体实施例对本发明的技术方案进行详细说明。
实施例1
一种治疗鲟鱼肠炎病的中草药，其原料包括：大蒜素、板蓝根、金银花、大黄、黄柏、五倍子、大青叶、野菊花。
实施例2
一种治疗鲟鱼肠炎病的中草药，其原料按重量份包括：大蒜素50份，板蓝根300份，金银花50份，大黄80份，黄柏30份，五倍子70份，大青叶100份，野菊花100份，黄芩40份，龙葵35份，生姜10份，石榴皮18份，赤芍8份，山楂35份，麦芽10份，玄明粉6份，陈皮10份，厚朴22份，甘草15份，枳实17份。
实施例3
一种治疗鲟鱼肠炎病的中草药，其原料按重量份包括：大蒜素80份，板蓝根200份，金银花100份，大黄50份，黄柏50份，五倍子50份，大青叶120份，野菊花50份，黄芩50份，龙葵15份，生姜30份，石榴皮4份，赤芍16份，山楂15份，麦芽18份，玄明粉1份，陈皮20份，厚朴14份，甘草25份，枳实11份。
实施例4
一种治疗鲟鱼肠炎病的中草药，其原料按重量份包括：大蒜素60份，板蓝根280份，金银花60份，大黄70份，黄柏35份，五倍子65份，大青叶105份，野菊花90份，黄芩42份，龙葵30份，生姜15份，石榴皮14份，赤芍10份，山楂30份，麦芽12份，玄明粉4份，陈皮12份，厚朴20份，甘草18份，枳实16份。
实施例5
一种治疗鲟鱼肠炎病的中草药，其原料按重量份包括：大蒜素70份，板蓝根220份，金银花80份，大黄60份，黄柏45份，五倍子55份，大青叶115份，野菊花70份，黄芩48份，龙葵20份，生姜25份，石榴皮8份，赤芍14份，山楂20份，麦芽16份，玄明粉2份，陈皮18份，厚朴16份，甘草22份，枳实12份。
实施例6
一种治疗鲟鱼肠炎病的中草药，其原料按重量份包括：大蒜素65g，板蓝根250g，金银花70g，大黄65g，黄柏40g，五倍子60g，大青叶110g，野菊花80g，黄芩45g，龙葵25g，生姜20g，石榴皮11g，赤芍12g，山楂25g，麦芽14g，玄明粉3g，陈皮15g，厚朴18g，甘草20g，枳实14g。
上述治疗鲟鱼肠炎病的中草药制备方法，将原料混合粉碎后，加水煎煮2.5h，过滤，取煎煮液冷却即得。
选取120尾肠炎病鲟鱼，先采用溴氯海因对鲟鱼养殖池和水体进行消毒，溴氯海因的用量为10kg/667m3，然后将本发明实施例6所得治疗鲟鱼肠炎病的中草药和鲟鱼配合饲料混合均匀，投喂。以连续使用3-5天为1个疗程，每两个疗程之间间隔3天。3个疗程后，对患有肠炎病鲟鱼进行检查，其中治愈101尾，有效18尾，无效1尾；有效率可达99.2％，治愈率为84.2％。
以上所述，仅为本发明较佳的具体实施方式，但本发明的保护范围并不局限于此，任何熟悉本技术领域的技术人员在本发明揭露的技术范围内，根据本发明的技术方案及其发明构思加以等同替换或改变，都应涵盖在本发明的保护范围之内。

Claims (5)

1.一种治疗鲟鱼肠炎病的中草药，其特征在于，其原料包括：大蒜素、板蓝根、金银花、大黄、黄柏、五倍子、大青叶、野菊花。
2.根据权利要求1所述治疗鲟鱼肠炎病的中草药，其特征在于，其原料按重量份包括：大蒜素50-80份，板蓝根200-300份，金银花50-100份，大黄50-80份，黄柏30-50份，五倍子50-70份，大青叶100-120份，野菊花50-100份。
3.根据权利要求1或2所述治疗鲟鱼肠炎病的中草药，其特征在于，其原料还包括：黄芩、龙葵、生姜、石榴皮、赤芍、山楂、麦芽、玄明粉、陈皮、厚朴、甘草、枳实。
4.根据权利要求1-3任一项所述治疗鲟鱼肠炎病的中草药，其特征在于，其原料按重量份包括：大蒜素50-80份，板蓝根200-300份，金银花50-100份，大黄50-80份，黄柏30-50份，五倍子50-70份，大青叶100-120份，野菊花50-100份，黄芩40-50份，龙葵15-35份，生姜10-30份，石榴皮4-18份，赤芍8-16份，山楂15-35份，麦芽10-18份，玄明粉1-6份，陈皮10-20份，厚朴14-22份，甘草15-25份，枳实11-17份。
5.一种如权利要求1-4任一项所述治疗鲟鱼肠炎病的中草药制备方法，其特征在于，将原料混合粉碎后，加水煎煮2-3h，过滤，取煎煮液冷却即得。
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