CN107367487A - A kind of handheld portable disease of skin auxiliary detection device - Google Patents
A kind of handheld portable disease of skin auxiliary detection device Download PDFInfo
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- CN107367487A CN107367487A CN201710438620.7A CN201710438620A CN107367487A CN 107367487 A CN107367487 A CN 107367487A CN 201710438620 A CN201710438620 A CN 201710438620A CN 107367487 A CN107367487 A CN 107367487A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
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- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
Disease of skin auxiliary detection device provided by the invention, the S light that the near-infrared laser of laser light source module outgoing is formed after PBS Amici prisms reflexes to the center of two-dimensional scanning micro mirror, so that laser beam be scanned through lens and cylinder microscope group into beam-expanding system after the collimated light beam diameter that is emitted exactly correspond to object lens Entry pupil diameters, by quarter wave plate component, object lens are reached after regulation optical quality, then focal beam spot is irradiated in skin histology sample face to be measured by object lens；The P light that the reflected light of formation is formed after being returned again along original optical path by PBS Amici prisms passes through prism and reaches apeture lens, refocusing is in multimode fibre wire jumper entrance end face, transmitted by multimode fibre wire jumper to signal detection module, and transmitted after detecting module detects to the processing of host computer image-forming module, realize that disease of skin aids in detection function, above-mentioned disease of skin auxiliary detection device, body volume is smaller, it can realize that handheld portable operates, can flexibly be applied to each difficult detection position.
Description
Technical field
The present invention relates to medical detecting Instrument design and manufacturing field, more particularly, to a kind of handheld portable disease of skin
Auxiliary detection device.
Background technology
Skin is first of human body defence, protect in-vivo tissue and organ from various mechanicalnesses, chemically, cause of disease it is micro-
The biological invasion for waiting harm.In recent years, with the continuous upgrading of food security and environmental problem etc., skin disease triggers strong
Health, life security and patients ' psychological problem are more by social concerns；Disease of skin is also the disease of most species simultaneously；And mesh
Preceding dermopathic diagnosis Main Basiss clinical manifestation and tissue pathology checking, the former depends on the clinical experience of doctor and master be present
Composition is seen, the latter belongs to invasive detection, can cause chromoma that the serious consequences such as transfer occur when serious.Study new use
In skin disease detects, effective, the noninvasive instrument of diagnosis is very necessary and is badly in need of.
Currently used for the equipment of disease of skin auxiliary detection device, such as CALIBER companies of the like product U.S.
VivaScope3000 products, its core scanning device selects polygonal-mirror, but its volume is larger, and integrated model uses base
Board-like mechanical structure, more heavy and redundancy.
The content of the invention
Have in view of that, it is necessary to the defects of existing for prior art, there is provided a kind of disease of skin of handheld portable is auxiliary
Help detection means.
To achieve the above object, the present invention uses following technical proposals：
A kind of handheld portable disease of skin auxiliary detection device, including laser light source module, PBS Amici prisms, two dimension
Scanning micro-mirror, scanning lens, cylinder mirror, quarter wave plate component, speculum, object lens, apeture lens, multimode fibre wire jumper, signal detection
Module and host computer image-forming module, wherein：
The near-infrared laser of the laser light source module outgoing is incident to the PBS Amici prisms, and rib is divided through the PBS
The S light formed after mirror is incident after PBS Amici prisms reflection to enter the two-dimensional scanning micro mirror, and the S light is through described two
Tie up incident into the thing after the scanning lens, cylinder mirror, quarter wave plate component and speculum successively again after scanning micro-mirror scans
Mirror, and focused on through the object lens on skin histology sample face to be measured, and the S light is after scanning lens and the cylinder mirror successively
The diameter of the collimated light beam of formation is corresponding with the object lens Entry pupil diameters；
The S light focuses on skin histology sample face to be measured caused reflected light successively through the thing through the object lens
It is incident after mirror, speculum, quarter wave plate component, cylinder mirror, scanning lens and two-dimensional scanning micro mirror to enter the PBS Amici prisms, institute
State PBS Amici prisms described in the P light transmissions that reflected light is formed after the PBS Amici prisms and focused on after the apeture lens
At the entrance end face of the multimode fibre wire jumper, the multimode fibre wire jumper is by the P optical transports to the signal detection mould
Block, the signal detection module detect the P light and handle the P optical transports of detection to the host computer image-forming module.
In some preferred embodiment, the laser light source module includes control box, is electrically connected with the chamber of the control box
Body and the laser being electrically connected with the cavity, the laser include single-mode polarization maintaining fiber.
In some preferred embodiment, the two-dimensional scanning micro mirror is MEMS two-dimensional scanning micro mirrors, and the MEMS two dimensions are swept
Fast axle and slow axis two-dimensional scan can be realized by retouching the single minute surface of micro mirror.
In some preferred embodiment, the signal detection module is avalanche diode.
In some preferred embodiment, the host computer image-forming module is computer.
The present invention the advantages of using above-mentioned technical proposal is：
Handheld portable disease of skin auxiliary detection device provided by the invention, the near-infrared of laser light source module outgoing swash
Light, the S light formed after the PBS Amici prisms reflex to two-dimensional scanning micro mirror minute surface center so that each angle laser light
Beam be scanned through lens and cylinder microscope group into beam-expanding system, the collimated light beam diameter of outgoing exactly corresponds to object lens Entry pupil diameters,
By quarter wave plate component, object lens are reached after adjusting optical quality, then focal beam spot is irradiated in skin histology sample to be measured by object lens
This face；The reflected light backtracking of formation, arrived respectively after object lens, quarter wave plate component, beam-expanding system and two-dimensional scanning micro mirror
Apeture lens is reached through prism up to the P light that PBS Amici prisms are formed, refocusing is in multimode fibre entrance end face, by multimode light
Fine wire jumper is transmitted to signal detection module, and is transmitted after detecting module detects to the processing of host computer image-forming module, realizes skin
Disease aids in detection function, handheld portable disease of skin auxiliary detection device provided by the invention, can meet that optical imagery will
Ask, body volume is smaller, it is possible to achieve hand-held, portable operation, it is real-time to disease of skin high-resolution, high accuracy in guarantee
While detection, it can flexibly be applied to each difficult detection position, suitable for each hospital dermatology department, beauty mechanism and scientific research institution
Deng numerous areas, market and have a extensive future.
Brief description of the drawings
Fig. 1 is handheld portable disease of skin auxiliary detection device structural representation provided in an embodiment of the present invention.
Fig. 2 is the structural representation of the laser light source module provided in an embodiment of the present invention.
Fig. 3 is the structural representation for the MEMS two-dimensional scanning micro mirrors that the above embodiment of the present invention provides.
Fig. 4 is the principle schematic of signal provided in an embodiment of the present invention transmission.
Wherein：Laser light source module 110, PBS Amici prisms 120, two-dimensional scanning micro mirror 130, scanning lens 140, cylinder mirror
150th, quarter wave plate component 160, speculum 170, object lens 180, apeture lens 190, multimode fibre wire jumper 210, signal detection module
220th, control box 111, cavity 112, laser 113, single-mode polarization maintaining fiber 114.
Embodiment
Fig. 1 is refer to, is a kind of handheld portable disease of skin auxiliary detection device 100 provided in an embodiment of the present invention,
Including laser light source module 110, PBS Amici prisms 120, two-dimensional scanning micro mirror 130, scanning lens 140, cylinder mirror 150,1/4 ripple
Piece component 160, speculum 170, object lens 180, apeture lens 190, multimode fibre wire jumper 210, signal detection module 220 and on
Position machine image-forming module (not shown).Wherein：
The near-infrared laser that the laser light source module 110 is emitted is incident to the PBS Amici prisms 120, through the PBS
The S light formed after Amici prism 120 is incident after the PBS Amici prisms 120 reflection to enter the two-dimensional scanning micro mirror 130,
The S light is after the two-dimensional scanning micro mirror 130 scanning again successively through the scanning lens 140, cylinder mirror 150, quarter wave plate component
160 and speculum 170 after it is incident enter the object lens 180, and focus on skin histology sample face to be measured through the object lens 180
On, and the diameter of collimated light beam that is formed after the scanning lens 140 and cylinder mirror 150 successively of the S light and the object lens 180
Entry pupil diameters are corresponding；
The S light focuses on skin histology sample face to be measured caused reflected light successively through described through the object lens 180
Enter to inject after object lens 180, speculum 170, quarter wave plate component 160, cylinder mirror 150, scanning lens 140 and two-dimensional scanning micro mirror 130
Enter the PBS Amici prisms 120, PBS described in the P light transmissions that the reflected light is formed after the PBS Amici prisms 120 is divided
Prism 120 is simultaneously focused at the entrance end face of the multimode fibre wire jumper 210 after the apeture lens 190, the multimode light
The P optical transports to the signal detection module 220, the signal detection module 220 are detected the P light simultaneously by fine wire jumper 210
The P optical transports of detection to the host computer image-forming module are handled.
Referring to Fig. 2, the structural representation of the laser light source module 110 provided for the above embodiment of the present invention.
The laser light source module 110 include control box 111, the cavity 112 for being electrically connected with the control box 111 and with
The laser 113 that the cavity 112 is electrically connected with, the laser 113 include single-mode polarization maintaining fiber 114.
It is appreciated that the laser light source module 110 that the above embodiment of the present invention provides is relative to traditional free space optical
The way of output, control box 111 and cavity 112 is external, and the single-mode polarization maintaining fiber 114 in laser 113 is directed in light path, from
And the main body of laser light source module 110 can be made to isolate antidetonation, greatly reduce device volume, while be more beneficial for laser and dissipate
Heat, improve power output stability, optics adjustment also more flexibly with it is convenient.
Preferably, the two-dimensional scanning micro mirror 130 is MEMS two-dimensional scanning micro mirrors, the list of the MEMS two-dimensional scanning micro mirrors
Individual minute surface can realize fast axle and slow axis two-dimensional scan.
Referring to Fig. 3, the structural representation of the MEMS two-dimensional scanning micro mirrors provided for the above embodiment of the present invention.
It is appreciated that the present invention realizes single minute surface two-dimensional scan function, mirror by using MEMS two-dimensional scanning micro mirrors
Face is fixed on working face by the axle of transverse and longitudinal two, due to being disposed with lattice coil around it, when electric current can produce magnetic by coil
, permanent magnet is placed with around minute surface, can also produce magnetic field, both, which interact, can produce Loulun magnetism, that is, drive minute surface high
Fast two-dimension vibration；Its fast axle is in sinusoidal waveform, and slow axis moves in zig-zag, and fast axle output comes and goes two-way trigger signal, realizes
High speed acquisition.
Further, since the minute surface two-dimension optical pivot angle of MEMS two-dimensional scanning micro mirrors meets system optics design requirement, in thing
Certain scanning field of view, and electroplate film are realized in face, improve the reflectivity to near-infrared laser；In addition, MEMS two-dimensional scans are micro-
Mirror body product is small, greatly reduces its system space occupation rate.
Preferably, the signal detection module 220 is avalanche diode.
Referring to Fig. 4, for the principle schematic of signal provided in an embodiment of the present invention transmission, the application uses multimode fibre
Wire jumper, can be right due to replacing pin hole using the fiber end face entrance of multimode fibre wire jumper by the P optical transports to avalanche diode
Light beam realizes space filtering, and its fiber cores footpath diameter corresponds to image planes focal beam spot size, about one times of Airy spot diameter, this side
Formula is advantageous to device radiation, improves sensitivity of detection, while greatly reduce volume.
Further, the host computer image-forming module is computer.
Handheld portable disease of skin auxiliary detection device 100 provided by the invention, laser light source module 110 are emitted near
Infrared laser, the S light formed after the PBS Amici prisms 120 reflex to the minute surface center of two-dimensional scanning micro mirror 130, made
Obtain each multi-angle laser light beam and be scanned through the beam-expanding system that lens 140 and cylinder mirror 150 form, the collimated light beam diameter of outgoing is just
Corresponding to the Entry pupil diameters of object lens 180, by quarter wave plate component, object lens 180 are reached after adjusting optical quality, then will by object lens 180
Focal beam spot is irradiated in skin histology sample face to be measured；The reflected light of formation is again by object lens 180, speculum 170, quarter wave plate
The P light that PBS Amici prisms 120 are formed is reached after component 160, beam-expanding system and two-dimensional scanning micro mirror 130 and reaches pin through prism
Hole lens 190, refocusing are transmitted to signal detection module in the entrance end face of multimode fibre wire jumper 210 by multimode fibre wire jumper 210
220, and transmitted after the detection of detecting module 220 to the processing of host computer image-forming module, realize that disease of skin aids in detection function, this
The handheld portable disease of skin auxiliary detection device provided is provided, optical imagery requirement can be met, body volume is smaller, can be with
Hand-held, portable operation is realized, can be flexible while ensureing to detect disease of skin high-resolution, high accuracy in real time
Be applied to each difficult detection position, suitable for numerous areas such as each hospital dermatology department, beauty mechanism and scientific research institutions, market and preceding
Scape is wide.
Certainly the handheld portable disease of skin auxiliary detection device of the present invention can also have a variety of conversion and remodeling, not
It is confined to the concrete structure of above-mentioned embodiment.In a word, protection scope of the present invention should include those for the common skill in this area
Obviously convert or substitute and retrofit for art personnel.
Claims (5)
1. a kind of handheld portable disease of skin auxiliary detection device, it is characterised in that be divided including laser light source module, PBS
Prism, two-dimensional scanning micro mirror, scanning lens, cylinder mirror, quarter wave plate component, speculum, object lens, apeture lens, multimode fibre are jumped
Line, signal detection module and host computer image-forming module, wherein：
The near-infrared laser of the laser light source module outgoing is incident to the PBS Amici prisms, after the PBS Amici prisms
The S light of formation is incident after PBS Amici prisms reflection to enter the two-dimensional scanning micro mirror, and the S light is swept through the two dimension
Retouch it is incident after the scanning lens, cylinder mirror, quarter wave plate component and speculum successively again after micro mirror scanning enter the object lens,
And focused on through the object lens on skin histology sample face to be measured, and S light shape after scanning lens and the cylinder mirror successively
Into collimated light beam diameter it is corresponding with the object lens Entry pupil diameters；
The S light focuses on skin histology sample face to be measured caused reflected light successively through object lens, anti-through the object lens
Incidence enters the PBS Amici prisms after penetrating mirror, quarter wave plate component, cylinder mirror, scanning lens and two-dimensional scanning micro mirror, described anti-
Penetrate PBS Amici prisms described in the P light transmissions that light is formed after the PBS Amici prisms and institute is focused on after the apeture lens
At the entrance end face for stating multimode fibre wire jumper, the multimode fibre wire jumper is by the P optical transports to the signal detection module, institute
Signal detection module is stated to detect the P light and handle the P optical transports of detection to the host computer image-forming module.
2. handheld portable disease of skin auxiliary detection device according to claim 1, it is characterised in that the laser light
Source module includes control box, the cavity for being electrically connected with the control box and the laser being electrically connected with the cavity, described
Laser includes single-mode polarization maintaining fiber.
3. handheld portable disease of skin auxiliary detection device according to claim 1, it is characterised in that the two dimension is swept
It is MEMS two-dimensional scanning micro mirrors to retouch micro mirror, and the single minute surface of the MEMS two-dimensional scanning micro mirrors can realize that fast axle and slow axis two dimension are swept
Retouch.
4. handheld portable disease of skin auxiliary detection device according to claim 1, it is characterised in that the signal is visited
Survey module is avalanche diode.
5. handheld portable disease of skin auxiliary detection device according to claim 1, it is characterised in that the host computer
Image-forming module is computer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710438620.7A CN107367487A (en) | 2017-06-12 | 2017-06-12 | A kind of handheld portable disease of skin auxiliary detection device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710438620.7A CN107367487A (en) | 2017-06-12 | 2017-06-12 | A kind of handheld portable disease of skin auxiliary detection device |
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| Publication Number | Publication Date |
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| CN107367487A true CN107367487A (en) | 2017-11-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710438620.7A Pending CN107367487A (en) | 2017-06-12 | 2017-06-12 | A kind of handheld portable disease of skin auxiliary detection device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108415155A (en) * | 2018-03-13 | 2018-08-17 | 北方工业大学 | Two-dimensional micro-galvanometer driving frequency adjusting system and method |
| CN113080848A (en) * | 2021-03-24 | 2021-07-09 | 深圳德技医疗器械有限公司 | Near-infrared skin detection device and method |
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| CN1306797A (en) * | 1999-07-30 | 2001-08-08 | 中国科学院光电技术研究所 | Adaptive optical retina imaging system (4) |
| CN1763504A (en) * | 2005-11-21 | 2006-04-26 | 哈尔滨工业大学 | Transmissive multi-beam confocal interference microscope with tens nanometer transverse resolution |
| CN1791822A (en) * | 2003-05-20 | 2006-06-21 | 卢西德有限公司 | Confocal microscope for imaging of selected locations of the body of a patient |
| CN102356310A (en) * | 2009-03-19 | 2012-02-15 | 皇家飞利浦电子股份有限公司 | Detector for birefringent objects |
| CN202342011U (en) * | 2011-11-02 | 2012-07-25 | 上海波汇通信科技有限公司 | Reflecting laser confocal skin microscope |
| CN104769481A (en) * | 2012-10-12 | 2015-07-08 | 统雷有限公司 | Compact, low dispersion, and low aberration adaptive optics scanning system |
| CN105424601A (en) * | 2015-12-22 | 2016-03-23 | 佛山市南海区欧谱曼迪科技有限责任公司 | Handheld confocal skin microscopic method and handheld confocal skin microscopic device |
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2017
- 2017-06-12 CN CN201710438620.7A patent/CN107367487A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1306797A (en) * | 1999-07-30 | 2001-08-08 | 中国科学院光电技术研究所 | Adaptive optical retina imaging system (4) |
| CN1791822A (en) * | 2003-05-20 | 2006-06-21 | 卢西德有限公司 | Confocal microscope for imaging of selected locations of the body of a patient |
| CN1763504A (en) * | 2005-11-21 | 2006-04-26 | 哈尔滨工业大学 | Transmissive multi-beam confocal interference microscope with tens nanometer transverse resolution |
| CN102356310A (en) * | 2009-03-19 | 2012-02-15 | 皇家飞利浦电子股份有限公司 | Detector for birefringent objects |
| CN202342011U (en) * | 2011-11-02 | 2012-07-25 | 上海波汇通信科技有限公司 | Reflecting laser confocal skin microscope |
| CN104769481A (en) * | 2012-10-12 | 2015-07-08 | 统雷有限公司 | Compact, low dispersion, and low aberration adaptive optics scanning system |
| CN105424601A (en) * | 2015-12-22 | 2016-03-23 | 佛山市南海区欧谱曼迪科技有限责任公司 | Handheld confocal skin microscopic method and handheld confocal skin microscopic device |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108415155A (en) * | 2018-03-13 | 2018-08-17 | 北方工业大学 | Two-dimensional micro-galvanometer driving frequency adjusting system and method |
| CN113080848A (en) * | 2021-03-24 | 2021-07-09 | 深圳德技医疗器械有限公司 | Near-infrared skin detection device and method |
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Application publication date: 20171121 |
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