CN107349300A - 一种治疗恶露不绝的中药组合物及其应用 - Google Patents

一种治疗恶露不绝的中药组合物及其应用 Download PDF

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CN107349300A
CN107349300A CN201610308586.7A CN201610308586A CN107349300A CN 107349300 A CN107349300 A CN 107349300A CN 201610308586 A CN201610308586 A CN 201610308586A CN 107349300 A CN107349300 A CN 107349300A
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张福梅
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Abstract

本发明涉及一种治疗恶露不绝的中药组合物及其应用。一种治疗恶露不绝的中药组合物,其活性成分由如下重量份的原料制备而成：红天葵2‑4份，救必应3‑4份，艾草5‑7份，石韦1‑3份，大蓟1‑3份，野三七4‑6份，柘木1‑4份，鲜地黄2‑4份，升麻3‑6份，红芪2‑4份，悬钩子4‑5份，飞龙掌血1‑2份，陈皮4‑6份，白术1‑2份，黄芪2‑3份，当归5‑6份，西红花1‑3份，刺五加2‑4份，蝎子七4‑6份，木贼5‑7份，香薷1‑3份。本治疗恶露不绝的中药组合物具有疗效好、费用低的优点，该中药组合物在治疗产后恶露不绝的药物中的应用中也具有广泛的前景，可广泛推广应用。

Description

一种治疗恶露不绝的中药组合物及其应用
技术领域
本发明属于中药领域，具体涉及一种治疗恶露不绝的中药组合物及其应用。
背景技术
产后血性恶露持续三个周以上仍然淋沥不断者，称为恶露不绝。一般为产后子宫排出的坏死脱落的蜕膜、血、官腔面渗出物等，是胎儿娩出后，由子宫排出的余血浊液，在正常情况下，恶露初为红血，继而变为浆色，后为白色粘稠状。如果超过20天，仍然淋沥不止，易于耗尽伤血，损伤正气，致令体虚。中医认为，本病的病机为(1)气虚，妇女气虚，正气不足，又因分娩失血耗气，气虚下陷、冲仁不固，以致恶露不断，(2)血瘀，胞衣胎膜残留为瘀，瘀阻冲任，新血难安，不得归经，以致恶露不净，(3)血热，素体阴虚，复因产时伤血，阴液更亏，阴虚内热，产后迫血下行，导致恶露不绝。随着二胎政策的实施，将会产生越来越多的高龄产妇，相较而言，高龄产妇得恶露不绝的几率较大，然而目前，对产后恶露不绝的治疗方法较多，西医治疗常采用器械清宫、对症止血疗法，所服用的西药主要有灭滴灵片、青霉素维钾片等；中医治疗药物更是多种多样。但是以上治疗均存在：治愈率较低、治疗费用较高的问题，难以达到满意的效果。
发明内容
为了解决现有技术存在的不足，本发明提供了一种治疗恶露不绝治愈率高且治疗费用相对合理的中药组合物及其应用。
本发明的具体技术方案如下：
一种治疗恶露不绝的中药组合物,其活性成分由如下重量份的原料制备而成：红天葵2-4份，救必应3-4份，艾草5-7份，石韦1-3份，大蓟1-3份，野三七4-6份，柘木1-4份，鲜地黄2-4份，升麻3-6份，红芪2-4份，悬钩子4-5份，飞龙掌血1-2份，陈皮4-6份，白术1-2份，黄芪2-3份，当归5-6份，西红花1-3份，刺五加2-4份，蝎子七4-6份，木贼5-7份，香薷1-3份。
进一步优化的，其活性成分由如下重量份的原料制备而成：红天葵2份，救必应3份，艾草6份，石韦2份，大蓟2份，野三七4份，柘木2份，鲜地黄3份，升麻3份，红芪3份，悬钩子4份，飞龙掌血2份，陈皮5份，白术2份，黄芪2份，当归5份，西红花2份，刺五加3份，蝎子七4份，木贼5份，香薷2份。
上述治疗恶露不绝的中药组合物在制备治疗产后恶露不绝的药物中的应用。
制备方法：将上述原料药组分按比例混合，取1kg混合物加水煎煮两次，第1次加相对于混合物质量5-7倍量水，煎煮2小时，第2次加相对于混合物质量3-6倍量水，煎煮1小时，滤过，合并滤液，浓缩至500ml。
用法用量：将上述浓缩所得的溶液，分成两次供病人食用，一次250ml，早晚各一次。
本中药组合物的药理分析：
红天葵，味甘,性凉，清热凉血，止咳化痰，解毒消肿，主外感高热；中暑，肺热咳嗽，咽喉肿痛，疔疮，瘰疬，疥癣，烫火伤，跌打瘀痛。
救必应，性寒，味苦，归肺经、肝经、胃经；泻火解毒、清热利湿、行气止痛、凉血止血。
艾草，入脾、肝、肾经；理气血，逐寒湿，温经，止血，安胎；治心腹冷痛，泄泻转筋，久痢，下血、月经不调等。
石韦，性微寒，味苦、甘，归肺经、膀胱经；利尿通淋、清热止血。
大蓟，入肝、肺经。凉血止血，行瘀消肿，主吐血、咯血、便血，尿血等。
野三七，性味苦，性温；散瘀止血，消肿定痛；主跌打损伤，风湿痛，咳血，吐血，便血，崩漏，病后虚弱和肺痨。
柘木，味甘，温，无毒；入肝、脾二经；化瘀止血，清肝明目，截疟；治崩漏，飞丝入目，疟疾。
鲜地黄，性味甘苦，寒；入心、肝、肾经；清热，凉血，生津；治温病伤阴，大热烦渴，舌绛，神昏，斑疹，吐血，衄血，血崩。
升麻，入肺、胃、脾经；升阳，发表，解毒；治头疼寒热，喉痛，口疮，久泻久利，脱肛，妇女崩，子宫下坠等。
红芪，归肺、脾经；补气升阳，固表止汗，利水消肿，生津养血，行滞通痹，托毒排脓，敛疮生肌。
悬钩子，性苦、凉，治醒酒，止渴，祛痰，解毒，治痛风，丹毒，遗精等。
飞龙掌血，性温，味辛、苦，归脾经、胃经；祛风止痛、散瘀止血。
陈皮，归肺、脾经，理气健脾，调中，燥湿，化痰；主治脾胃气滞，消化不良。
白术，归脾、胃经，健脾益气，燥湿利水，止汗，安胎。
黄芪，性甘、微温；归肺、脾、肝、肾经；表虚自汗，阴虚盗汗，急性肾炎水肿，阳气虚弱，疮疡溃破，肺气虚证，气虚衰弱。
当归，性甘、辛、温，归肝、心、脾经；补血，活血，调经止痛，润燥滑肠；治血虚诸证、月经不调、经闭、痛经、症瘕结聚、崩漏。
西红花，味甘，性平；归心、肝经；活血化瘀，凉血解毒，解郁安神。
刺五加，补气药，具有补虚扶弱的功效，可来预防或治疗体质虚弱之症候，滋补强壮，延年益寿。
蝎子七，归脾，胃，大肠经；清热解毒、活血止血、解毒止痛。
木贼，入肺、肝、胆经；疏风清热，凉血止血，明目退翳；主风热目赤，迎风流泪，血痢等。
香薷，性辛，微温；入肺、胃经；发汗解暑，行水散湿，温胃调中。
本中药组合物以救必应、石韦、鲜地黄、蝎子七和木贼清热凉血，以大蓟、柘木、野三七、红天葵、飞龙掌血、红芪和西红花行瘀消肿，活血化瘀，以艾草、升麻、陈皮、白术、黄芪、当归、刺五加补气血、健胃益脾的功效，以悬钩子和香薷调理机体、增强免疫力,各药材协同作用，从而达到治疗产后恶露不绝的效果。
本治疗恶露不绝的中药组合物具有疗效好、费用低的优点，该中药组合物在治疗产后恶露不绝的药物中的应用中也具有广泛的前景，可广泛推广应用。
具体实施方式
下面结合实施例，对本治疗恶露不绝的中药组合物及其应用作进一步的详解。
实施例1
称取红天葵200g，救必应300g，艾草500g，石韦300g，大蓟200g，野三七400g，柘木100g，鲜地黄400g，升麻300g，红芪400g，悬钩子400g，飞龙掌血100g，陈皮400g，白术100g，黄芪200g，当归600g，西红花100g，刺五加200g，蝎子七600g，木贼500g，香薷100g；
将上述原料药组分按比例混合，取1kg混合物加水煎煮两次，第1次加相对于混合物质量5-7倍量水，煎煮2小时，第2次加相对于混合物质量3-6倍量水，煎煮1小时，滤过，合并滤液，浓缩至500ml。
实施例2
称取红天葵400g，救必应400g，艾草700g，石韦100g，大蓟200g，野三七600g，柘木400g，鲜地黄200g，升麻600g，红芪200g，悬钩子500g，飞龙掌血200g，陈皮600g，白术200g，黄芪300g，当归500g，西红花200g，刺五加400g，蝎子七400g，木贼700g，香薷300g；
将上述原料药组分按比例混合，取1kg混合物加水煎煮两次，第1次加相对于混合物质量5-7倍量水，煎煮2小时，第2次加相对于混合物质量3-6倍量水，煎煮1小时，滤过，合并滤液，浓缩至500ml。
实施例3
称取红天葵200g，救必应300g，艾草600g，石韦200g，大蓟200g，野三七400g，柘木200g，鲜地黄300g，升麻300g，红芪300g，悬钩子400g，飞龙掌血200g，陈皮500g，白术200g，黄芪200g，当归500g，西红花200g，刺五加300g，蝎子七400g，木贼500g，香薷200g；
将上述原料药组分按比例混合，取1kg混合物加水煎煮两次，第1次加相对于混合物质量5-7倍量水，煎煮2小时，第2次加相对于混合物质量3-6倍量水，煎煮1小时，滤过，合并滤液，浓缩至500ml。
临床试验
自2014年1月-2014年11月，在济南市中医院妇产科按照如下标准选择出现恶露不绝患者200例：
1.恶露出现16天后，量没有减少的迹象，有臭味；
2.经检查，子宫大且软，位于后位：
3.B超检测宫内有残留组织；
此200例患者随机分为4组，每组为50人，分别为组1、组2、组3和组4，组1使用本实施例1所得药剂治疗，组2使用本实施例2所得药剂治疗，组3使用本实施例3所得药剂治疗，使用量均为一剂，分早、晚两次服用，组4使用灭滴灵片，早晚各一片；5天后检查结果。
疗效标准：
痊愈：恶露停止、恶露消失、阴道停止出血；
有效：恶露减少一半以上，症状逐步好转；
无效：症状无明显改善，甚至还有加重现象。
治疗结果如下：
由本临床试验可得，本中药组合物相对于传统的西药治疗具有更高的治愈率，然而，相对于西药，价格上更便宜，所以，具有更强的实用性。

Claims (3)

1.一种治疗恶露不绝的中药组合物,其特征在于，其活性成分由如下重量份的原料制备而成：红天葵2-4份，救必应3-4份，艾草5-7份，石韦1-3份，大蓟1-3份，野三七4-6份，柘木1-4份，鲜地黄2-4份，升麻3-6份，红芪2-4份，悬钩子4-5份，飞龙掌血1-2份，陈皮4-6份，白术1-2份，黄芪2-3份，当归5-6份，西红花1-3份，刺五加2-4份，蝎子七4-6份，木贼5-7份，香薷1-3份。
2.根据权利要求1所述的中药组合物，其特征在于，其活性成分由如下重量份的原料制备而成：红天葵2份，救必应3份，艾草6份，石韦2份，大蓟2份，野三七4份，柘木2份，鲜地黄3份，升麻3份，红芪3份，悬钩子4份，飞龙掌血2份，陈皮5份，白术2份，黄芪2份，当归5份，西红花2份，刺五加3份，蝎子七4份，木贼5份，香薷2份。
3.权利要求1或2所述的中药组合物在制备治疗产后恶露不绝的药物中的应用。
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