CN107348491A - Prevent liver diseases drink and preparation method thereof - Google Patents

Prevent liver diseases drink and preparation method thereof Download PDF

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Publication number
CN107348491A
CN107348491A CN201710733884.5A CN201710733884A CN107348491A CN 107348491 A CN107348491 A CN 107348491A CN 201710733884 A CN201710733884 A CN 201710733884A CN 107348491 A CN107348491 A CN 107348491A
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China
Prior art keywords
parts
liver diseases
drink
buckwheat
liver
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CN201710733884.5A
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王雪
燕承勇
张珍
孙立新
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Guizhou Jian Ruian Pharmaceutical Co Ltd
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Guizhou Jian Ruian Pharmaceutical Co Ltd
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Priority to CN201710733884.5A priority Critical patent/CN107348491A/en
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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38—Other non-alcoholic beverages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention provides a kind of prevention liver diseases drink and preparation method thereof, is related to technical field of health care.The raw material of the drink includes the following component counted in parts by weight：5~35 parts of dandelion, 8~25 parts of the root of kudzu vine, 10~30 parts of black tartary buckwheat, 12~35 parts of moringa seeds, 20~50 parts of folium lycii, 15~40 parts of FLOS CHRYSANTHEMI from Hangzhou of China, 10~35 parts of eucommia Bark male flower, 25~60 parts of rose, 20~50 parts of mulberries, 25~55 parts of coix seed, 20~55 parts of ampelopsis grossdentata, 5~20 parts of black garlic, 5~10 parts of radix glycyrrhizae, 10~30 parts of buckwheat.Each medicine is used cooperatively, and preferably liver can be protected, and preferably prevents various liver diseases.Dandelion, moringa seeds, radix glycyrrhizae and rose can reduce the cool property of FLOS CHRYSANTHEMI from Hangzhou of China, the root of kudzu vine, buckwheat and mulberries, and can accelerate toxin expelling of the other drugs to liver, further reduce the ill probability of liver.

Description

Prevent liver diseases drink and preparation method thereof
Technical field
The present invention relates to technical field of health care, in particular to one kind prevention liver diseases drink and its preparation Method.
Background technology
In recent years, because a large amount of of alcohol eat, and food additive, the use or residual of chemicals and agricultural and veterinary chemicals Stay, cause chemically hepatic lesion and the rising of alcoholic liver injury quantity.At present, China's chronic liver injury caused by long-term alcohol Crowd's quantity is more and more, and chronic liver injury, which further develops, can cause the serious diseases such as alcoholic hepatitis, hepatic sclerosis and liver cancer. Alcohol is a kind of well-known phenomenon to hepar damnification, it will be apparent that hepatic injury mark is that cellular enzymes are penetrated into blood plasma, is threatened The health of people.Found by zoopery, long term alcohol intake causes the weight of animals to reduce, and this is probably due to food intake Caused by amount reduction and metabolic disorder.
The traditional Chinese medical science thinks that liver is human body " shield of toxin expelling ", and liver has three big physiological functions：One main store blood, two main catharsis, three masters Muscle.Strong liver, it is human immunity and the important guarantee of health.If liver function declines, store blood deficiency, catharsis just occurs Imbalance, tendon and joint joint stuffiness, whole body is feeble, hypopsia, blurred vision, and body's resistance to disease declines, various diseases Disease will avail oneself of the opportunity to get in.Therefore, the protection of liver is particularly significant for health.
The content of the invention
It is an object of the invention to provide one kind to prevent liver diseases drink, and the drink has stronger anti-oxidant, anti-inflammatory And immunocompetence, liver can be played a very good protection.
Another object of the present invention is to provide the preparation method of prevention liver diseases drink, can make full use of in raw material Active ingredient and method simply easily implement.
The present invention is solved its technical problem and realized using following technical scheme.
The present invention proposes a kind of prevention liver diseases drink, and the raw material of the drink including counting such as the following group in parts by weight Point：
5~35 parts of dandelion, 8~25 parts of the root of kudzu vine, 10~30 parts of black tartary buckwheat, 12~35 parts of moringa seeds, folium lycii 20~50 Part, 15~40 parts of FLOS CHRYSANTHEMI from Hangzhou of China, 10~35 parts of eucommia Bark male flower, 25~60 parts of rose, 20~50 parts of mulberries, coix seed 25~55 Part, 20~55 parts of ampelopsis grossdentata, 5~20 parts of black garlic, 5~10 parts of radix glycyrrhizae, 10~30 parts of buckwheat.
The present invention proposes a kind of preparation method for preventing liver diseases drink, including：Dandelion, the root of kudzu vine, black tartary buckwheat is peppery Wooden seed, folium lycii, FLOS CHRYSANTHEMI from Hangzhou of China, eucommia Bark male flower, rose, mulberries, coix seed, ampelopsis grossdentata, black garlic, radix glycyrrhizae and buckwheat enter Row mixing.
The beneficial effect of prevention liver diseases drink and preparation method thereof provided in an embodiment of the present invention is：
The embodiment of the present invention provides a kind of prevention liver diseases drink, and it is mainly made of following raw material：Dandelion, Pueraria lobota It is root, black tartary buckwheat, moringa seeds, folium lycii, FLOS CHRYSANTHEMI from Hangzhou of China, eucommia Bark male flower, rose, mulberries, coix seed, ampelopsis grossdentata, black garlic, sweet Grass and buckwheat.Liver can be played a good protection by the use of natural plants as raw material, each raw material synthesis use, in advance Anti- liver diseases.Black tartary buckwheat, eucommia Bark male flower, coix seed, black garlic and ampelopsis grossdentata contain substantial amounts of nutritional ingredient, big portion Point nutritional ingredient be respectively provided with it is anti-oxidant, remove free radical, antiinflammatory action, liver diseases can not only be prevented, additionally it is possible to liver Play good maintenance and toxin expelling effect.Folium lycii, FLOS CHRYSANTHEMI from Hangzhou of China, the root of kudzu vine, buckwheat and mulberries can cooperate with foregoing four kinds of medicines Preferably liver is protected, preferably prevents various liver diseases.Dandelion, moringa seeds, radix glycyrrhizae and rose can The cool property of FLOS CHRYSANTHEMI from Hangzhou of China, the root of kudzu vine, buckwheat and mulberries is reduced, and toxin expelling of the other drugs to liver can be accelerated, is further reduced The ill probability of liver.The embodiment of the present invention also provides a kind of preparation method for preventing liver diseases drink, and this method is simply easy OK, the natural nutrient component of each raw material can be made full use of, drink is played preferably prevention liver diseases effect.
Embodiment
, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer Technical scheme be clearly and completely described.Unreceipted actual conditions person, builds according to normal condition or manufacturer in embodiment The condition of view is carried out.Agents useful for same or the unreceipted production firm person of instrument, it is the conventional production that can be obtained by commercially available purchase Product.
Prevention liver diseases drink to the embodiment of the present invention and preparation method thereof is specifically described below.
One kind prevention liver diseases drink, the raw material of the drink include the following component counted in parts by weight：
5~35 parts of dandelion, 8~25 parts of the root of kudzu vine, 10~30 parts of black tartary buckwheat, 12~35 parts of moringa seeds, folium lycii 20~50 Part, 15~40 parts of FLOS CHRYSANTHEMI from Hangzhou of China, 10~35 parts of eucommia Bark male flower, 25~60 parts of rose, 20~50 parts of mulberries, coix seed 25~55 Part, 20~55 parts of ampelopsis grossdentata, 5~20 parts of black garlic, 5~10 parts of radix glycyrrhizae, 10~30 parts of buckwheat.
Further, raw material includes the following component counted in parts by weight：
10~25 parts of dandelion, 14~20 parts of the root of kudzu vine, 15~25 parts of black tartary buckwheat, 18~27 parts of moringa seeds, folium lycii 30~ 40 parts, 20~30 parts of FLOS CHRYSANTHEMI from Hangzhou of China, 15~25 parts of eucommia Bark male flower, 40~50 parts of rose, 30~40 parts of mulberries, coix seed 30~40 Part, 30~40 parts of ampelopsis grossdentata, 10~15 parts of black garlic, 6~9 parts of radix glycyrrhizae, 15~25 parts of buckwheat.
Further, raw material includes the following component counted in parts by weight：
15~20 parts of dandelion, 16~18 parts of the root of kudzu vine, 18~22 parts of black tartary buckwheat, 20~25 parts of moringa seeds, folium lycii 33~ 37 parts, 23~28 parts of FLOS CHRYSANTHEMI from Hangzhou of China, 19~23 parts of eucommia Bark male flower, 44~48 parts of rose, 34~38 parts of mulberries, coix seed 33~37 Part, 32~36 parts of ampelopsis grossdentata, 12~14 parts of black garlic, 7~8 parts of radix glycyrrhizae, 18~22 parts of buckwheat.
Ampelopsis grossdentata is also referred to as cogongrass cliff berry, Wuyuan snow chrysanthemum, vine tea, is a kind of Wild Liane.It is containing needed by human 17 kinds of amino acid, 14 kinds of trace elements, are especially enriched in plant flavone.Flavones content is very abundant in ampelopsis grossdentata tender leaf, number Claim flavones king, content is up to 45.52%, mainly there is dihydromyricetin, myricetin, myricetrin etc..Pharmacological research confirms, shows tooth snake Flavones in grape has anti-oxidant, protect liver, anti-inflammation, adjusts a variety of effects such as immune.Excessive consumption of alcohol, liver catabolism Alcohol burden will aggravate, easily form alcoholic liver injury, also referred to as chemical damage, easily induce hepatitis, fatty liver, The hepatopathys such as hepatic sclerosis.Ampelopsis grossdentata can reduce serum ALT concentration, improve liver cell biomembrane activity and permeability, regulation Liver cell oxidative metabolism function, it is anti-oxidant, remove superfluous free radical, eliminating inflammation and expelling toxin, the damage of hepatic tissue cell is repaired, in preventing The generation and development of property fat accumulation and hepatic sclerosis.So as to improve the ability of liver decomposition and inversion alcohol, mitigate alcohol to liver Dirty infringement.
Coix seed is the dry mature kernal of Job's tears, a variety of amino rich in starch, protein, vitamin and needed by human body Acid, its vitamin B contained have protective effect to liver.Though contained carbohydrate is without the more of rice in coix seed, But contained protein, fat are 2~3 times of rice, also containing vitamin B1 and Coixol, Coixenolide, triterpene Amino acid necessary to compound, and our human bodies.These are all hepatitis B patients, especially damp abundance due to splenic asthenia type hepatitis B, second Indispensable nutriment in hepatic cirrhosis patients complicated with ascites rehabilitation metabolism after liver.Coix seed can strengthen body immunity and anti-inflammatory Ability, coix seed oil have facilitation to cellular immunity, humoral immunity.And it is to treat hepatitis B especially to adjust immunologic function The important effective way of chronic hepatitis B.
The bark of eucommia is the tree of the double strains of male and female, and eucommia Bark male flower is the flower that bark of eucommia Xiong Shu is opened.Eucommia Bark male flower is effectively planted containing kind more than 60 Thing composition, such as lignin, iridoids, Phenylpropanoid Glycosides class active material (such as Geniposidic acid, chlorogenic acid, peach jaurel Glucoside), rosin spirit disaccharide glucoside, flavones, alkaloid, amino acid, polysaccharide and mineral element Zn, Mn, Cu, Fe, Ca, P, B, Mg, K Deng.Its amino acid content is up to 21.47%, and the content of calcium is up to 0.92%, and Zn content reaches 51mg/100g, and active ingredient is the most comprehensive, And content is higher.Eucommia Bark male flower, the elite of all barks of eucommia is summarized, possess all health-care efficacies of the plant bark of eucommia.The bark of eucommia is male Flower is rich in a variety of unrighted acids, Quercetin, vitamin E, Aucubin, the Portugals of rosin spirit two such as alpha-linolenic acid, linoleic acid A variety of poly- iridoid glycosideses such as grape glucoside and the active ingredient of other bark of eucommia plants, have stronger anti-oxidant and free Base Scavenging activity.
Black tartary buckwheat is one kind of buckwheat, and it has high nutritive value, is described as " kings of five cereals ", long-term use of black hardship Buckwheat can effectively including preventing hypertension, cancer a variety of diseases.Not only it is rich in black tartary buckwheat in other cereal crops almost Without rutin (VP) and selenium element (Se), while also containing 18 kinds of amino acid, 9 kinds of aliphatic acid (VF), abundant dietary fiber, Chlorophyll, crude protein, carbohydrate, mineral matter and trace element, content is reasonable, and without sugar and cholesterol.Bitter buckwheat class Flavonoid substance is easily oxidized, and makes it have the function of removing free radical.The molecular structure of Tartary buckwheat biological flavonoids composition, which meets, to be had It is theoretical to imitate phenolic hydroxyl group, there is extremely strong radical scavenging activity, they have 5 hydroxyls, can sufficiently be used as hydrogen donor, make Radical reduction, so as to play a part of removing free radical, reach health care, anticancer, the purpose of resisting cardiovascular disease.Tartary buckwheat biological Flavonoids is to CCl4Caused increasing for content of liver MDA (MDA liver lipid peroxidations end-product) has obvious inhibitory action； Consumption of the hepatic injury to glutathione (GSH) can be mitigated；Cyto-architectural integrality can be protected, prevents from turning ammonia in liver cell The lyoenzymes such as enzyme from cell because spilling and activity rise.The protect liver mechanism of Tartary buckwheat biological flavonoids is finally its antioxygen Change the effect with Green Tea Extract.
Black garlic, black tartary buckwheat, eucommia Bark male flower, coix seed and ampelopsis grossdentata contain substantial amounts of nutritional ingredient, most of Nutritional ingredient is respectively provided with anti-oxidant, removing free radical, antiinflammatory action, can not only prevent liver diseases, additionally it is possible to which liver is risen Acted on to good maintenance and toxin expelling.
FLOS CHRYSANTHEMI from Hangzhou of China is bitter in taste, pungent, is slightly cold, Return liver, the heart channel of Hang-Shaoyin, contains abundant alantol, amino acid, FLOS CHRYSANTHEMI from Hangzhou of China lactone, micro The Multiple components such as element.The traditional Chinese medical science thinks that FLOS CHRYSANTHEMI from Hangzhou of China fragrant taste is slightly bitter, and the property of medicine is more plain, has the releasing poison that clears away the dampness and heat The effect of element, swelling and pain relieving, the thermal sensation come for summer weather humid tropics emit and aphthosis hot-tempered and because of its appearance There is therapeutic action well, irascibility can be gone, control headache rhinorrhea, the hot effect that disappears of avoiding heat.It is the anti-inflammatory of FLOS CHRYSANTHEMI from Hangzhou of China, anti-oxidant Ability is stronger, can reduce liver inner lipid peroxidization, removes free radical, protects liver plasma membrane, maintains the normal penetrating of film Property, prevent liver cell from producing too high TNF.FLOS CHRYSANTHEMI from Hangzhou of China can cooperate with together with the root of kudzu vine, mulberries, folium lycii, buckwheat Foregoing four kinds of medicines are preferably protected to liver, preferably prevent various liver diseases.
Moringa seeds are the seed of Moringa tree, and good application valency is suffered from fields such as food, medicine, health care, cosmetics Value, because being rich in seed oil of Moringa oleigera, it is reducing blood fat, blood pressure, weight-reducing, adjusts stomach, protect liver abstinence from alcohol, strengthens human immunity All there is significant curative effect in terms of power.The active component contained in moringa seeds, protected alcohol stomach and liver can be effectively directed to, and And alcohol can be accelerated and distributed.Dandelion, moringa seeds and rose with the use of can reduce FLOS CHRYSANTHEMI from Hangzhou of China, the root of kudzu vine, buckwheat with And the cool property of mulberries, and toxin expelling of the other drugs to liver can be accelerated, further reduce the ill probability of liver.
Prevent to can further include the following component counted in parts by weight in the raw material of liver diseases drink：Auxiliary material 5 ~10 parts, 2~8 parts of flavouring.Auxiliary material can use 2~5 parts of dextrin, and flavouring can use 2~5 parts of stevioside.Certainly, it is auxiliary Material and flavouring can also select other materials.
The embodiment of the present invention also provides a kind of preparation method of above-mentioned prevention liver diseases drink.
Coix seed, black tartary buckwheat are subjected to frying, slow fire frying can be used, coix seed frying is micro- yellow, black tartary buckwheat frying Fine fisssure.Frying can not only reduce both cold, also help both and given play to more preferable drug effect, be also beneficial to subsequently to having Imitate the extraction of composition.
By the dandelion, root of kudzu vine, moringa seeds, folium lycii, FLOS CHRYSANTHEMI from Hangzhou of China, eucommia Bark male flower, rose, mulberries, ampelopsis grossdentata, black Coix seed, black tartary buckwheat after garlic, radix glycyrrhizae, buckwheat and frying are soaked to obtain hybrid medicine.Soak time is 5~10 small When.Immersed with beneficial to the recovery rate for improving active ingredient, active ingredient is set more to be dissolved in solution.
The hybrid medicine obtained after immersion is decocted to extraction 1~3 time at 90~100 DEG C, each extraction time is 2~5 Hour, obtain extract solution.Extraction can make full use of raw material repeatedly, the active ingredient in raw material is farthest dissolved into molten In liquid.It is of course also possible to use some chemical reagent carry out the extraction of active ingredient, such as ethanol.
It is 1.15-1.35 by relative density is concentrated into after extract solution centrifugation removal of impurities.The auxiliary materials such as dextrin auxiliary can be added Extract solution is further molded.The flavourings such as stevioside or FOS can also be further added, extract solution is adjusted Taste, drink taste is set more to meet popular taste.Finally the mixture of paste is dried, crush, sieve, sterilize, dispensed, Obtain preventing liver diseases drink.Wherein, concentrate condition can be 60~70 DEG C, to relative density be 1.15~1.35 it is thick Cream.Wherein, sieving can cross 80~100 mesh sieves.Sterilizing is sterilized using Co60- gamma Rays.The drink good water solubility, drink With conveniently, being easy to, people are outgoing to be carried.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
The present embodiment provides a kind of prevention liver diseases drink and preparation method thereof, specific as follows：
Weigh dandelion 5g, root of kudzu vine 8g, black tartary buckwheat 10g, moringa seeds 12g, folium lycii 20g, FLOS CHRYSANTHEMI from Hangzhou of China 15g, eucommia Bark male flower 10g, rose 25g, mulberries 20g, coix seed 25g, ampelopsis grossdentata 20g, black garlic 5g, radix glycyrrhizae 5g, buckwheat 10g.Soak 10 hours, the removal of impurity is gone, is rinsed well with purified water.Above-mentioned raw materials are added in 3000ml water, 2h is boiled at 90 DEG C, is carried Take liquid.Extract solution is centrifuged and cleaned, is further concentrated to the thick paste that relative density is 1.15.It will crush, mix after thick paste forced air drying, 100 mesh sieves are crossed, obtain dry extract.Sterilized using Co60- gamma Rays, under aseptic condition, dispense and produce prevention liver disease Sick drink.
Embodiment 2
The present embodiment provides a kind of prevention liver diseases drink and preparation method thereof, specific as follows：
Weigh dandelion 35g, root of kudzu vine 25g, black tartary buckwheat 30g, moringa seeds 35g, folium lycii 50g, FLOS CHRYSANTHEMI from Hangzhou of China 40g, bark of eucommia hero Flower 35g, rose 60g, mulberries 50g, coix seed 55g, ampelopsis grossdentata 55g, black garlic 20g, radix glycyrrhizae 10g, buckwheat 30g.By the heart of a lotus seed The seed of jog's tears, black tartary buckwheat are mixed with other raw materials, and soaked 5 hours again after carrying out frying, are gone the removal of impurity, are rushed with purified water Wash clean.Above-mentioned raw materials are added in 5000ml water, 5h is boiled at 100 DEG C, obtain the first extract solution.First extract solution is got out Afterwards, then into the dregs of a decoction 3000ml water is added, is boiled at 90 DEG C 3 hours, obtains the second extract solution.By the first extract solution and second Extract solution centrifugation removal of impurities, is further concentrated to the thick paste that relative density is 1.35.It will crush, mix after thick paste forced air drying, cross 80 mesh Sieve, obtains dry extract.Sterilized using Co60- gamma Rays, under aseptic condition, dispense and produce prevention liver diseases drink.
Embodiment 3
The present embodiment provides a kind of prevention liver diseases drink and preparation method thereof, specific as follows：
Weigh dandelion 10g, root of kudzu vine 14g, black tartary buckwheat 15g, moringa seeds 18g, folium lycii 30g, FLOS CHRYSANTHEMI from Hangzhou of China 20g, bark of eucommia hero Flower 15g, rose 40g, mulberries 30g, coix seed 30g, ampelopsis grossdentata 30g, black garlic 10g, radix glycyrrhizae 6g, buckwheat 15g.By Job's tears Benevolence, black tartary buckwheat are mixed with other raw materials, and soaked 8 hours again after carrying out frying, are gone the removal of impurity, are rinsed with purified water Totally.Above-mentioned raw materials are added in 4000ml water, 4h is boiled at 100 DEG C, obtain the first extract solution.First extract solution is got out Afterwards, then into the dregs of a decoction 2000ml water is added, is boiled at 90 DEG C 3 hours, obtains the second extract solution.Second extract solution is got out Afterwards, then into the dregs of a decoction 1000ml water is added, is boiled at 90 DEG C 2 hours, obtains the 3rd extract solution.By the first extract solution, second Extract solution and the centrifugation removal of impurities of the 3rd extract solution, are further concentrated to the thick paste that relative density is 1.25.By powder after thick paste forced air drying It is broken, mix, cross 90 mesh sieves, obtain dry extract.Sterilized using Co60- gamma Rays, under aseptic condition, dispense and produce prevention Liver diseases drink.
Embodiment 4
The present embodiment provides a kind of prevention liver diseases drink and preparation method thereof, specific as follows：
Weigh dandelion 25g, root of kudzu vine 20g, black tartary buckwheat 25g, moringa seeds 27g, folium lycii 40g, FLOS CHRYSANTHEMI from Hangzhou of China 30g, bark of eucommia hero Flower 25g, rose 50g, mulberries 40g, coix seed 40g, ampelopsis grossdentata 40g, black garlic 15g, radix glycyrrhizae 9g, buckwheat 25g.By Job's tears Benevolence, black tartary buckwheat are mixed with other raw materials, and soaked 8 hours again after carrying out frying, are gone the removal of impurity, are rinsed with purified water Totally.Above-mentioned raw materials are added in 4000ml water, 4h is boiled at 100 DEG C, obtain the first extract solution.First extract solution is got out Afterwards, then into the dregs of a decoction 2000ml water is added, is boiled at 90 DEG C 3 hours, obtains the second extract solution.Second extract solution is got out Afterwards, then into the dregs of a decoction 1000ml water is added, is boiled at 90 DEG C 2 hours, obtains the 3rd extract solution.By the first extract solution, second Extract solution and the centrifugation removal of impurities of the 3rd extract solution, are further concentrated to the thick paste that relative density is 1.15.Dextrin 2g is added into thick paste And stevioside 2g is mixed.It will crush, mix after thick paste forced air drying again, cross 110 mesh sieves, obtain dry extract.Using Co60- Gamma Rays sterilize, and under aseptic condition, dispense and produce prevention liver diseases drink.
Embodiment 5
The present embodiment provides a kind of prevention liver diseases drink and preparation method thereof, specific as follows：
Weigh dandelion 15g, root of kudzu vine 16g, black tartary buckwheat 18g, moringa seeds 20g, folium lycii 33g, FLOS CHRYSANTHEMI from Hangzhou of China 23g, bark of eucommia hero Flower 19g, rose 44g, mulberries 34g, coix seed 33g, ampelopsis grossdentata 32g, black garlic 12g, radix glycyrrhizae 7g, buckwheat 18g.By Job's tears Benevolence, black tartary buckwheat are mixed with other raw materials again after carrying out frying, are ground.Sterilized using Co60- gamma Rays, aseptic condition Under, dispense and produce prevention liver diseases drink.
Embodiment 6
The present embodiment provides a kind of prevention liver diseases drink and preparation method thereof, specific as follows：
Weigh dandelion 20g, root of kudzu vine 18g, black tartary buckwheat 22g, moringa seeds 25g, folium lycii 37g, FLOS CHRYSANTHEMI from Hangzhou of China 28g, bark of eucommia hero Flower 23g, rose 48g, mulberries 38g, coix seed 37g, ampelopsis grossdentata 36g, black garlic 14g, radix glycyrrhizae 8g, buckwheat 22g.Will be all Raw material is mixed, grinding.Sterilized using Co60- gamma Rays, under aseptic condition, dispense and produce prevention liver diseases drink Product.
Embodiment 7
The present embodiment provides a kind of prevention liver diseases drink and preparation method thereof, specific as follows：
Weigh dandelion 18g, root of kudzu vine 17g, black tartary buckwheat 20g, moringa seeds 23g, folium lycii 35g, FLOS CHRYSANTHEMI from Hangzhou of China 25g, bark of eucommia hero Flower 20g, rose 45g, mulberries 36g, coix seed 35g, ampelopsis grossdentata 34g, black garlic 13g, radix glycyrrhizae 7.5g, buckwheat 20g.By original Material is mixed and soaked 9 hours, is gone the removal of impurity, is rinsed well with purified water.Above-mentioned raw materials are added in 4000ml water, in 100 4h is boiled at DEG C, obtains the first extract solution.After first extract solution is got out, then 2000ml water is added into the dregs of a decoction, at 90 DEG C Boil 3 hours, obtain the second extract solution.By the first extract solution, the centrifugation removal of impurities of the second extract solution, being further concentrated to relative density is 1.25 thick paste.Dextrin 5g and stevioside 5g is added into thick paste to mix.It will crush, mix, mistake after thick paste forced air drying again 110 mesh sieves, obtain dry extract.Sterilized using Co60- gamma Rays, under aseptic condition, dispense and produce prevention liver diseases Drink.
Embodiment 8
The present embodiment provides a kind of prevention liver diseases drink and preparation method thereof, specific as follows：
Weigh dandelion 6g, root of kudzu vine 10g, black tartary buckwheat 12g, moringa seeds 14g, folium lycii 48g, FLOS CHRYSANTHEMI from Hangzhou of China 36g, eucommia Bark male flower 32g, rose 57g, mulberries 47g, coix seed 52g, ampelopsis grossdentata 51g, black garlic 11g, radix glycyrrhizae 7g, buckwheat 23g.Raw material is mixed Merging is soaked 6 hours, is gone the removal of impurity, is rinsed well with purified water.Above-mentioned raw materials are added in 3000ml water, at 100 DEG C 5h is boiled, obtains the first extract solution.After first extract solution is got out, then 1000ml water is added into the dregs of a decoction, boiled at 100 DEG C 3h, obtain the second extract solution.By the first extract solution, the second extract solution centrifugation removal of impurities, be further concentrated to relative density be 1.15 it is thick Cream.Dextrin 10g, stevioside 3g and FOS 5g is added into thick paste to mix.It will crush, mix after thick paste forced air drying again It is even, 80 mesh sieves are crossed, obtain dry extract.Sterilized using Co60- gamma Rays, under aseptic condition, dispense and produce prevention liver Disease drink.
Test example
Some healthy ICR mouse are taken, are divided into 6 groups, including blank control group, 1 group of model group and embodiment ~4 groups.Blank control group gavage gives physiological saline；Model group gavage gives 3.5g/kg/day alcohol；1 group~4 groups of embodiment Gavage gives 3.5g/kg/day alcohol+corresponding embodiment 1~4 obtained prevention liver diseases drink 5g/kg/ respectively respectively day.The daily gavage given the test agent of animal once, is weighed weekly twice, and given the test agent dosage is adjusted by body weight, after continuous 60 days, Each group animal fasting overnight 15 hours, execution take serum and hepatic tissue, carry out the detection of indices.Use data handling system SPSS22.0 carries out statistical analysis.
Liver function index in serum is detected：Serum Mid-Heaven Gate winter propylhomoserin transaminase is determined using corresponding reagent box (AST), alanine aminotransferase (ALT), the activity of gamma-glutamyl enzyme (GGT), as a result as shown in table 1.
Liver function index in hepatic tissue is detected：Superoxide dismutase in mitochondria is determined using corresponding reagent box (SOD) mitochondria GSH-PX activity-s- transferases (GST), glutathione peroxidase (GSH-PX), are removed.As a result such as the institute of table 2 Show.
Liver function index in the serum of each group of table 1 experiment
Index AST(IU/L) ALT(IU/L) GGT(IU/L)
Blank control group 47.87±17.56 22.54±3.05 5.23±3.53
Model group 77.58±16.45 34.21±2.89 8.47±2.93
Embodiment 1 49.52±15.36 23.47±3.01 6.25±3.06
Embodiment 2 48.98±16.68 23.61±2.89 6.01±3.12
Embodiment 3 47.57±17.20 22.63±3.18 5.87±2.56
Embodiment 4 47.87±16.49 22.87±3.29 5.35±3.14
The test result of table 1 shows that ethanol postincubation can dramatically increase AST, ALT and GGT activity, this show liver plasma membrane by To damage.The intervention of the obtained prevention liver diseases drink of embodiment 1~4 can significantly reduce AST, ALT and GGT activity.Table Bright drink provided in an embodiment of the present invention has protection, reparation and stabilization to liver plasma membrane.
The liver function index of the hepatic tissue of each group of table 2 experiment
The test result of table 2 shows that Ethanol intake can significantly reduce the activity of three kinds of antioxidases (SOD, GSH-Px, GST). Wherein model group SOD activity reduces, and shows it to O2-Scavenging activity reduce, but drink intervention provided in an embodiment of the present invention can Improve SOD activity.Normal group level can be allowed to come to, improves and removes O2-Ability, mitigate ethoxy free radical generation And hepatic injury caused by lipid peroxidation.Model group GSH-Px activity reduction, drink intervention provided in an embodiment of the present invention It is remarkably improved enzyme activity.
Embodiments described above is part of the embodiment of the present invention, rather than whole embodiments.The reality of the present invention The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention Example.Based on the embodiment in the present invention, what those of ordinary skill in the art were obtained under the premise of creative work is not made Every other embodiment, belongs to the scope of protection of the invention.

Claims (10)

1. one kind prevention liver diseases drink, it is characterised in that the raw material of the prevention liver diseases drink is included by weight The following component of number meter：
5~35 parts of dandelion, 8~25 parts of the root of kudzu vine, 10~30 parts of black tartary buckwheat, 12~35 parts of moringa seeds, 20~50 parts of folium lycii, Hangzhoupro 15~40 parts of chrysanthemum, 10~35 parts of eucommia Bark male flower, 25~60 parts of rose, 20~50 parts of mulberries, 25~55 parts of coix seed, show tooth 20~55 parts of porcelain ampelopsis, 5~20 parts of black garlic, 5~10 parts of radix glycyrrhizae, 10~30 parts of buckwheat.
2. prevention liver diseases drink according to claim 1, it is characterised in that the raw material includes counting in parts by weight Following component：
10~25 parts of the dandelion, 14~20 parts of the root of kudzu vine, 15~25 parts of the black tartary buckwheat, the moringa seeds 18~27 Part, 30~40 parts of the folium lycii, 20~30 parts of the FLOS CHRYSANTHEMI from Hangzhou of China, 15~25 parts of the eucommia Bark male flower, the rose 40~ 50 parts, 30~40 parts of the mulberries, 30~40 parts of the coix seed, 30~40 parts of the ampelopsis grossdentata, the black garlic 10~ 15 parts, 6~9 parts of the radix glycyrrhizae, 15~25 parts of the buckwheat.
3. prevention liver diseases drink according to claim 1, it is characterised in that the raw material includes counting in parts by weight Following component：
15~20 parts of the dandelion, 16~18 parts of the root of kudzu vine, 18~22 parts of the black tartary buckwheat, the moringa seeds 20~25 Part, 33~37 parts of the folium lycii, 23~28 parts of the FLOS CHRYSANTHEMI from Hangzhou of China, 19~23 parts of the eucommia Bark male flower, the rose 44~ 48 parts, 34~38 parts of the mulberries, 33~37 parts of the coix seed, 32~36 parts of the ampelopsis grossdentata, the black garlic 12~ 14 parts, 7~8 parts of the radix glycyrrhizae, 18~22 parts of the buckwheat.
4. the prevention liver diseases drink according to any one of claims 1 to 3, it is characterised in that the raw material also includes The following component counted in parts by weight：5~10 parts of auxiliary material, 2~8 parts of flavouring.
5. prevention liver diseases drink according to claim 4, it is characterised in that the auxiliary material includes 2~5 parts of dextrin, The flavouring includes 2~5 parts of stevioside.
A kind of 6. preparation method of prevention liver diseases drink as described in any one of Claims 1 to 5, it is characterised in that bag Include：By the dandelion, the root of kudzu vine, the black tartary buckwheat, the moringa seeds, the folium lycii, the FLOS CHRYSANTHEMI from Hangzhou of China, the bark of eucommia Male flower, the rose, the mulberries, the coix seed, the ampelopsis grossdentata, the black garlic, the radix glycyrrhizae and described Buckwheat is mixed.
7. the preparation method of prevention liver diseases drink according to claim 6, it is characterised in that before mixing, by institute State coix seed, the black tartary buckwheat carries out frying.
8. the preparation method of prevention liver diseases drink according to claim 6, it is characterised in that after mixing, by gained Hybrid medicine soaks 5~10 hours.
9. the preparation method of prevention liver diseases drink according to claim 8, it is characterised in that described in after immersion Hybrid medicine decocts extraction 1~3 time at 90~100 DEG C, and each extraction time is 2~5 hours, obtains extract solution.
10. the preparation method of prevention liver diseases drink according to claim 9, it is characterised in that by the extract solution Relative density is concentrated into after centrifugation removal of impurities as 1.15~1.35.
CN201710733884.5A 2017-08-24 2017-08-24 Prevent liver diseases drink and preparation method thereof Pending CN107348491A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107927257A (en) * 2017-12-01 2018-04-20 贵州健瑞安药业有限公司 A kind of health protection tea for preventing hepatic sclerosis and liver cancer and preparation method thereof
CN112535225A (en) * 2020-09-23 2021-03-23 梧州市华夏医药科技有限公司 Eucommia ulmoides male flower substitutional tea and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102114202A (en) * 2009-12-31 2011-07-06 福建归真堂药业股份有限公司 Liver-protecting composition and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102114202A (en) * 2009-12-31 2011-07-06 福建归真堂药业股份有限公司 Liver-protecting composition and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107927257A (en) * 2017-12-01 2018-04-20 贵州健瑞安药业有限公司 A kind of health protection tea for preventing hepatic sclerosis and liver cancer and preparation method thereof
CN112535225A (en) * 2020-09-23 2021-03-23 梧州市华夏医药科技有限公司 Eucommia ulmoides male flower substitutional tea and preparation method thereof

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Application publication date: 20171117