CN107320599A - A kind of Chinese medicine preparation for being used to treat polycystic ovary syndrome - Google Patents
A kind of Chinese medicine preparation for being used to treat polycystic ovary syndrome Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/88—Liliopsida (monocotyledons)
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Abstract
The invention discloses a kind of Chinese medicine preparation for being used to treat polycystic ovary syndrome, it is made up of the component of following weight：10 14 grams of dried orange peel, 8 12 grams of the tuber of pinellia processed, 8 12 grams of rhizoma atractylodis, 8 12 grams of grass-leaved sweetflag, 8 12 grams of Poria cocos, 8 12 grams of Ligusticum wallichii, 8 12 grams of Radix Angelicae Sinensis, 14 16 grams of rhizoma cyperi processed, 8 12 grams of the root bark of tree peony, 10 14 grams of rhizoma atractylodis macrocephalae, interrupted 10 14 grams, 46 grams of arisaema cum bile, 10 14 grams of stir-baked CORTEX EUCOMMIAE, 8 12 grams of stir-bake to yellowish cypress.The present invention is subject to science configuration according to secret prescription handed down in the family from generation to generation, and good effect is treated both principal and secondary aspect of disease, and 100% effective percentage is can reach in actual therapeutic, easy to use, without any side effects.
Description
Technical field
The present invention relates to technical field of Chinese medicine, and in particular to a kind of Chinese medicine system for being used to treat polycystic ovary syndrome
Agent.
Background technology
It is well known that polycystic ovary syndrome is puberty and the relatively conventional E＆M irregularity of the women of child-bearing age
Disease, its incidence of disease is about 5%-lO%, changed with continuation ovulation failure or many capsule samples of No-clay weak interbed, excessive androgen, ovary and
Insulin resistance is characterized.It is reproductive dysfunction and abnormal carbohydrate metabolism and a kind of special disease deposited.Main clinical manifestation is
The symptom of the metabolic disorder such as reproductive dysfunction and obesity, acne, crinosity such as delayed menstrual cycle, amenorrhoea, infertile, ovary increase.Cause
The mechanism that it develops is unclear so far, therefore in clinical real category difficult and complicated illness.
The medicine of Modern medical therapy polycystic ovary syndrome, it is main use antagonism androgen and sex hormone artificial cycle with
And insulin sensitivity treatment is improved, and TCM Gynecology then often uses merely kidney and spleen invigorating, promoting blood circulation for regulating menstruation treatment, these methods
Though it is effective in cure, but still show many drawbacks：Many patients suffer to be difficult to adhere to enough treatments to the sensitivity of said medicine side effect
Journey；Separately there are many patients to talk " hormone " discolorations, refuse to take hormone therapy scheme, moreover more importantly simple hormone scheme or
Simple to use oral medicinal herb, clinical effectiveness is really difficult to use up people's will, therefore is called difficult and complicated illness.Again because its age of onset is early, morbidity
The high and patient of rate is often examined with infertile and first, and doctor and patient feels the weight of responsibility, the trip so numerous doctors seek assiduously
Effective method.
The content of the invention
The technical problems to be solved by the invention are to provide that a kind of formula is simple, cure rate it is high be used for treat many capsule ovum
The Chinese medicine preparation of nest syndrome.
The technical problems to be solved by the invention are realized using following technical scheme：
A kind of Chinese medicine preparation for being used to treat polycystic ovary syndrome, is made up of the component of following weight：Dried orange peel 10-14
Gram, 8-12 grams of the tuber of pinellia processed, 8-12 grams of rhizoma atractylodis, 8-12 grams of grass-leaved sweetflag, 8-12 grams of Poria cocos, 8-12 grams of Ligusticum wallichii, 8-12 grams of Radix Angelicae Sinensis, system it is fragrant
Attached 14-16 grams, 8-12 grams of the root bark of tree peony, 10-14 grams of rhizoma atractylodis macrocephalae, interrupted 10-14 grams, 4-6 grams of arisaema cum bile, 10-14 grams of stir-baked CORTEX EUCOMMIAE, stir-bake to yellowish
8-12 grams of cypress.
The preferable weight of each component is：12 grams of dried orange peel, 10 grams of the tuber of pinellia processed, 10 grams of rhizoma atractylodis, 10 grams of grass-leaved sweetflag, 10 grams of Poria cocos,
10 grams of Ligusticum wallichii, 10 grams of Radix Angelicae Sinensis, 15 grams of rhizoma cyperi processed, 10 grams of the root bark of tree peony, 12 grams of rhizoma atractylodis macrocephalae, interrupted 12 grams, 5 grams of arisaema cum bile, stir-baked CORTEX EUCOMMIAE 12
Gram, 10 grams of stir-bake to yellowish cypress.
The preparation method of above-mentioned Chinese medicine is as follows：
(1) dried orange peel, Poria cocos and Radix Angelicae Sinensis are put into pulverizer together, powder is ground into using pulverizer, cross 180-200 mesh medicines
Sieve, obtains powder I；
(2) by powder I in vacuum and low temperature cold air drying equipment, holding 60-90 minutes at a temperature of 40-50 DEG C, then
It is put into fresh-keeping warehouse and preserves 6-8 hours, fresh-keeping storehouse temperature is in 6-8 DEG C, humidity more than 85%；Dried powder is low in low temperature
Several hours are deposited under wet environment can fully absorb moisture, beneficial to the precipitation of drug effect；
(3) by the tuber of pinellia processed, rhizoma atractylodis, grass-leaved sweetflag, Ligusticum wallichii, rhizoma cyperi processed, the root bark of tree peony, rhizoma atractylodis macrocephalae, discontinuously, arisaema cum bile, stir-baked CORTEX EUCOMMIAE and
Stir-bake to yellowish cypress is crushed together, is crossed 60-80 mesh medicine sieve, is obtained powder II；
(4) powder II is soaked with pure water, kept for 40-60 minutes at 38-45 DEG C of temperature, then using powder II as base
Number, adds the pure water of 1.5 times of weight, stirs, and regulation intermediate pH value is 5.0-6.5, and suitable pH value can keep medicinal material
Never degenerate, hydrolyzed 20-24 hours at 55 ± 2 DEG C of temperature, obtain feed liquid I；
(5) using filter press to feed liquid I carry out press filtration, collect filtrate, obtain feed liquid II, by feed liquid II be heated to 55 DEG C-
70 DEG C, 2 hours are incubated, ensure that product quality is stable, high income carries out hyperfiltration afterwards, through high pressure homogenizer homogeneous,
Homogenization pressure is 15~20MPa, through 200 mesh screens, and it is stand-by that collection filtrate obtains feed liquid III；
(6) feed liquid III is sufficiently mixed with powder I, adds pill auxiliary material, pill is made, enters in vacuum dryer
Row drying, is packaged to be finished product.
Polycystic ovary syndrome belongs to the traditional Chinese medical science " through few ", " amenorrhoea " category.The traditional Chinese medical science thinks that kidney qi is filled and contains slow, is passed through after tide less,
Later stage and go, or even amenorrhoea；Kidney essense cloth falls deficiency, dysfunction of the spleen in transportation and transformation, and wet turbid interior strongly fragrant, the hot stasis of blood of phlegm is stagnant；Disease belongs to " kidney deficiency stasis, phlegm wet
Stasis blocking ".Control and blood is controlled with kidney-nourishing, dehumidify resolving sputum.
The rules for the treatment of：Kidney-nourishing controls blood, and dehumidify resolving sputum.
Fang Xie：Dried orange peel, the tuber of pinellia processed, arisaema cum bile, stir-bake to yellowish cypress in we：Turbid dehumidifying is let out, it is stagnant to seek phlegm row, clearing Ying heat and cooling blood；Rhizoma cyperi,
Radix Angelicae Sinensis, the root bark of tree peony, Ligusticum wallichii：Cool blood, promoting blood circulation, the stagnant menstruation regulating of row；Poria cocos, rhizoma atractylodis, rhizoma atractylodis macrocephalae：Invigorating the spleen, eliminating dampness, with the source of producing phlegm of shutting out；It is disconnected
The continuous, bark of eucommia：The strong kidney of kidney tonifying.
Instructions of taking：2 times a day, one time 5 grams, morning and evening warm water delivery service, treatment 1 week is 1 course for the treatment of, treats 3 courses for the treatment of
Observe curative effect.
Chinese medicine of the present invention carried out before putting goods on the market substantial amounts of animal acute toxicity test, long-term toxicity test for animals with
And a large amount of clinical tests for the treatment of disease, science and objectively foundation are provided to the use link that medicine input treats disease.
Its test method and result of the test difference are as follows：
(1) animal acute toxicity test is carried out to pill prepared by the present invention：
Medicine：Bulk drug used in the present invention is commercially available from common Chinese shop, and its specification meets national Chinese medicine mark
It is accurate.
Experimental animal：Small white mouse, body weight is bought in 50g or so, male and female random selection by market.
Method and result：Take small white mouse 10, it is hungry 20 hours or so, feed 9g 3 times per natural gift by every, continuously feed one
In week, observe 10 days, mouse activity is normal, non-toxic reaction, no death.Show oral liquid without acute toxicity, clinical medicine dose
Safety.
(2) long-term toxicity test for animals is carried out to pill prepared by the present invention：
Experimental animal：Big white mouse, body weight is bought in 120-130g, male and female random selection by market.
Method and result：Big white mouse 20 is taken, is divided into 2 groups, every group 10, wherein the 1st group as administration group, it is every by every
Feed for it 2 times, each 2g, the 2nd group of diet as a control group, once a day, is continuously fed 90 days, body weight is surveyed, in last
24 hours sacrificed by decapitation after single administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organ, tissues observed form such as kidney
Change, observe dosage effect, observation diet, activity change, experiment prove administration group compared with control group without significantly become
Change, equal non-toxic reaction is a kind of safe drugs.
Diagnostic criteria：
1. clinical symptoms：System is caused due to No-clay weak interbed and Hyperandrogenism, typical patient pelvioscopy abnormal uterine, but can
Touch bilateral ovaries increase.
(1) menstrual disorder：Predominantly amenorrhoea, mostly secondary amenorrhea, often have infrequent menstruation, very few a, Shao Shuoke before amenorrhoea
For blood supply or inadequate luteal function.
(2) crinosity：Chaeta, pubes are dense, and typical pubes can be in male's distribution, topical acne etc..
(3) it is fat：Generally moderate obesity.
(4) it is infertile：Caused by No-clay weak interbed.
2. in order to verify clinical efficacy, observe case：In October, 2015-2016 year October, include meet the diagnosis of this disease and
The patient of inclusive criteria totally 100,25-50 years old ages.
3. treatment method
Instructions of taking：2 times a day, one time 5 grams, morning and evening warm water delivery service, treatment 1 week is 1 course for the treatment of, treats 3 courses for the treatment of
Observe curative effect.
4. efficacy determination：
Cure：Menstrual cycle is normal, and hormonal readiness determines normal, and B ultrasound monitoring has normal ovulation, many capsule sex character of B ultrasound ovary
As disappearing；
Effectively：Menstrual cycle is normal, and hormonal readiness determines the reduction of LH/FSH ratios, and T values are also reduced, and B ultrasound monitoring has
Dominant follicle is grown and No-clay weak interbed, and many capsules of B ultrasound ovary are reduced or single survey disappears；
It is invalid：Symptom changes unobvious, and hormonal readiness is determined without change, and B ultrasound monitoring shows ovum without dominant follicle growth, B ultrasound
The many capsule sex character of nest are as unchanged.
Treatment results：
Recovery from illness 20, accounts for 20%, effective 60, accounts for 60%, effectively account for 20%, invalid 0, total effective rate 100%.
The beneficial effects of the invention are as follows：The present invention is subject to science configuration according to secret prescription handed down in the family from generation to generation, and good effect is treated both principal and secondary aspect of disease,
100% effective percentage is can reach in actual therapeutic, it is easy to use, it is without any side effects.
Embodiment
In order that the technical means, the inventive features, the objects and the advantages of the present invention are easy to understand, tie below
Specific embodiment is closed, the present invention is expanded on further.
Embodiment 1
A kind of Chinese medicine preparation for being used to treat polycystic ovary syndrome, is made up of the component of following weight：12 grams of dried orange peel, system
10 grams of the tuber of pinellia, 10 grams of rhizoma atractylodis, 10 grams of grass-leaved sweetflag, 10 grams of Poria cocos, 10 grams of Ligusticum wallichii, 10 grams of Radix Angelicae Sinensis, 15 grams of rhizoma cyperi processed, 10 grams of the root bark of tree peony,
12 grams of rhizoma atractylodis macrocephalae, interrupted 12 grams, 5 grams of arisaema cum bile, 12 grams of stir-baked CORTEX EUCOMMIAE, 10 grams of stir-bake to yellowish cypress.
The preparation method of above-mentioned Chinese medicine is as follows：
(1) dried orange peel, Poria cocos and Radix Angelicae Sinensis are put into pulverizer together, powder is ground into using pulverizer, cross 180-200 mesh medicines
Sieve, obtains powder I；
(2) by powder I in vacuum and low temperature cold air drying equipment, holding 60-90 minutes at a temperature of 40-50 DEG C, then
It is put into fresh-keeping warehouse and preserves 6-8 hours, fresh-keeping storehouse temperature is in 6-8 DEG C, humidity more than 85%；Dried powder is low in low temperature
Several hours are deposited under wet environment can fully absorb moisture, beneficial to the precipitation of drug effect；
(3) by the tuber of pinellia processed, rhizoma atractylodis, grass-leaved sweetflag, Ligusticum wallichii, rhizoma cyperi processed, the root bark of tree peony, rhizoma atractylodis macrocephalae, discontinuously, arisaema cum bile, stir-baked CORTEX EUCOMMIAE and
Stir-bake to yellowish cypress is crushed together, is crossed 60-80 mesh medicine sieve, is obtained powder II；
(4) powder II is soaked with pure water, kept for 40-60 minutes at 38-45 DEG C of temperature, then using powder II as base
Number, adds the pure water of 1.5 times of weight, stirs, and regulation intermediate pH value is 5.0-6.5, and suitable pH value can keep medicinal material
Never degenerate, hydrolyzed 20-24 hours at 55 ± 2 DEG C of temperature, obtain feed liquid I；
(5) using filter press to feed liquid I carry out press filtration, collect filtrate, obtain feed liquid II, by feed liquid II be heated to 55 DEG C-
70 DEG C, 2 hours are incubated, ensure that product quality is stable, high income carries out hyperfiltration afterwards, through high pressure homogenizer homogeneous,
Homogenization pressure is 15~20MPa, through 200 mesh screens, and it is stand-by that collection filtrate obtains feed liquid III；
(6) feed liquid III is sufficiently mixed with powder I, adds pill auxiliary material, pill is made, enters in vacuum dryer
Row drying, is packaged to be finished product.
Embodiment 2
A kind of Chinese medicine preparation for being used to treat polycystic ovary syndrome, is made up of the component of following weight：14 grams of dried orange peel, system
8 grams of the tuber of pinellia, 12 grams of rhizoma atractylodis, 8 grams of grass-leaved sweetflag, 12 grams of Poria cocos, 8 grams of Ligusticum wallichii, 12 grams of Radix Angelicae Sinensis, 14 grams of rhizoma cyperi processed, 12 grams of the root bark of tree peony, stir-fry are white
10 grams of art, interrupted 14 grams, 4 grams of arisaema cum bile, 14 grams of stir-baked CORTEX EUCOMMIAE, 8 grams of stir-bake to yellowish cypress.
The preparation method of above-mentioned Chinese medicine is as follows：
(1) dried orange peel, Poria cocos and Radix Angelicae Sinensis are put into pulverizer together, powder is ground into using pulverizer, cross 180-200 mesh medicines
Sieve, obtains powder I；
(2) by powder I in vacuum and low temperature cold air drying equipment, holding 60-90 minutes at a temperature of 40-50 DEG C, then
It is put into fresh-keeping warehouse and preserves 6-8 hours, fresh-keeping storehouse temperature is in 6-8 DEG C, humidity more than 85%；Dried powder is low in low temperature
Several hours are deposited under wet environment can fully absorb moisture, beneficial to the precipitation of drug effect；
(3) by the tuber of pinellia processed, rhizoma atractylodis, grass-leaved sweetflag, Ligusticum wallichii, rhizoma cyperi processed, the root bark of tree peony, rhizoma atractylodis macrocephalae, discontinuously, arisaema cum bile, stir-baked CORTEX EUCOMMIAE and
Stir-bake to yellowish cypress is crushed together, is crossed 60-80 mesh medicine sieve, is obtained powder II；
(4) powder II is soaked with pure water, kept for 40-60 minutes at 38-45 DEG C of temperature, then using powder II as base
Number, adds the pure water of 1.5 times of weight, stirs, and regulation intermediate pH value is 5.0-6.5, and suitable pH value can keep medicinal material
Never degenerate, hydrolyzed 20-24 hours at 55 ± 2 DEG C of temperature, obtain feed liquid I；
(5) using filter press to feed liquid I carry out press filtration, collect filtrate, obtain feed liquid II, by feed liquid II be heated to 55 DEG C-
70 DEG C, 2 hours are incubated, ensure that product quality is stable, high income carries out hyperfiltration afterwards, through high pressure homogenizer homogeneous,
Homogenization pressure is 15~20MPa, through 200 mesh screens, and it is stand-by that collection filtrate obtains feed liquid III；
(6) feed liquid III is sufficiently mixed with powder I, adds pill auxiliary material, pill is made, enters in vacuum dryer
Row drying, is packaged to be finished product.
Embodiment 3
A kind of Chinese medicine preparation for being used to treat polycystic ovary syndrome, is made up of the component of following weight：10 grams of dried orange peel, system
12 grams of the tuber of pinellia, 8 grams of rhizoma atractylodis, 12 grams of grass-leaved sweetflag, 8 grams of Poria cocos, 12 grams of Ligusticum wallichii, 8 grams of Radix Angelicae Sinensis, 16 grams of rhizoma cyperi processed, 8 grams of the root bark of tree peony, stir-fry are white
14 grams of art, interrupted 10 grams, 6 grams of arisaema cum bile, 10 grams of stir-baked CORTEX EUCOMMIAE, 12 grams of stir-bake to yellowish cypress.
The preparation method of above-mentioned Chinese medicine is as follows：
(1) dried orange peel, Poria cocos and Radix Angelicae Sinensis are put into pulverizer together, powder is ground into using pulverizer, cross 180-200 mesh medicines
Sieve, obtains powder I；
(2) by powder I in vacuum and low temperature cold air drying equipment, holding 60-90 minutes at a temperature of 40-50 DEG C, then
It is put into fresh-keeping warehouse and preserves 6-8 hours, fresh-keeping storehouse temperature is in 6-8 DEG C, humidity more than 85%；Dried powder is low in low temperature
Several hours are deposited under wet environment can fully absorb moisture, beneficial to the precipitation of drug effect；
(3) by the tuber of pinellia processed, rhizoma atractylodis, grass-leaved sweetflag, Ligusticum wallichii, rhizoma cyperi processed, the root bark of tree peony, rhizoma atractylodis macrocephalae, discontinuously, arisaema cum bile, stir-baked CORTEX EUCOMMIAE and
Stir-bake to yellowish cypress is crushed together, is crossed 60-80 mesh medicine sieve, is obtained powder II；
(4) powder II is soaked with pure water, kept for 40-60 minutes at 38-45 DEG C of temperature, then using powder II as base
Number, adds the pure water of 1.5 times of weight, stirs, and regulation intermediate pH value is 5.0-6.5, and suitable pH value can keep medicinal material
Never degenerate, hydrolyzed 20-24 hours at 55 ± 2 DEG C of temperature, obtain feed liquid I；
(5) using filter press to feed liquid I carry out press filtration, collect filtrate, obtain feed liquid II, by feed liquid II be heated to 55 DEG C-
70 DEG C, 2 hours are incubated, ensure that product quality is stable, high income carries out hyperfiltration afterwards, through high pressure homogenizer homogeneous,
Homogenization pressure is 15~20MPa, through 200 mesh screens, and it is stand-by that collection filtrate obtains feed liquid III；
(6) feed liquid III is sufficiently mixed with powder I, adds pill auxiliary material, pill is made, enters in vacuum dryer
Row drying, is packaged to be finished product.
Model case：
1. Zhang, female, 28 years old, Jieshou City Shu Zhuan towns, on November 17th, 2015 went to a doctor.Since patient's readme to first menses,
Menstruation is abnormal always, and amount is few, 50 days or so menstrual cycle.Polycystic ovary syndrome is made a definite diagnosis through hospital.Take implementation of the present invention
Example 1 medicine, 3 courses for the treatment of, the menstrual cycle is normal；B ultrasound shows bilateral ovaries normal in size, is discontinued.
2. Liu so-and-so, female, 34 years old, Jieshou City turn round and look at market town, on May 14th, 2016 go to a doctor.Body type of having a medical check-up is fat, shank-feathering compared with
It is many, Vagina supersonic inspection：Intrauterine thickness 5mm, left ovary 4.6cm × 2.4cm × 2.7cm, right ovary 5.4cm × 4.3cm ×
2.3cm, bilateral ovaries are shown in the small ovarian follicle more than 10 2-9mm, are diagnosed as polycystic ovary syndrome.Continuously take implementation of the present invention
After 4 courses for the treatment of of medicine prepared by example 2, inspection, which is shown, to be all gone well.
The general principle and principal character and advantages of the present invention of the present invention has been shown and described above.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the simply explanation described in above-described embodiment and specification is originally
The principle of invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its
Equivalent thereof.
Claims (5)
1. a kind of Chinese medicine preparation for being used to treat polycystic ovary syndrome, it is characterised in that be made up of the component of following weight：It is old
10-14 grams of skin, 8-12 grams of the tuber of pinellia processed, 8-12 grams of rhizoma atractylodis, 8-12 grams of grass-leaved sweetflag, 8-12 grams of Poria cocos, 8-12 grams of Ligusticum wallichii, Radix Angelicae Sinensis 8-12
Gram, 14-16 grams of rhizoma cyperi processed, 8-12 grams of the root bark of tree peony, 10-14 grams of rhizoma atractylodis macrocephalae, interrupted 10-14 grams, 4-6 grams of arisaema cum bile, stir-baked CORTEX EUCOMMIAE 10-14
Gram, 8-12 grams of stir-bake to yellowish cypress.
A kind of be used to treat the Chinese medicine preparation of polycystic ovary syndrome 2. according to claim 1, it is characterised in that by with
The component of lower weight is made：12 grams of dried orange peel, 10 grams of the tuber of pinellia processed, 10 grams of rhizoma atractylodis, 10 grams of grass-leaved sweetflag, 10 grams of Poria cocos, 10 grams of Ligusticum wallichii, when
Return 10 grams, 15 grams of rhizoma cyperi processed, 10 grams of the root bark of tree peony, 12 grams of rhizoma atractylodis macrocephalae, interrupted 12 grams, 5 grams of arisaema cum bile, 12 grams of stir-baked CORTEX EUCOMMIAE, stir-bake to yellowish cypress 10
Gram.
3. the preparation method of Chinese medicine preparation described in a kind of claim 1 or 2, it is characterised in that step is as follows：
(1) dried orange peel, Poria cocos and Radix Angelicae Sinensis are put into pulverizer together, powder are ground into using pulverizer, cross 180-200 mesh medicine sieve,
Obtain powder I；
(2) by powder I in vacuum and low temperature cold air drying equipment, kept for 60-90 minutes, be then placed at a temperature of 40-50 DEG C
Preserved 6-8 hours in fresh-keeping warehouse, fresh-keeping storehouse temperature is in 6-8 DEG C, humidity more than 85%；Dried powder is in low temperature and low humidity ring
Several hours are deposited under border can fully absorb moisture, beneficial to the precipitation of drug effect；
(3) by the tuber of pinellia processed, rhizoma atractylodis, grass-leaved sweetflag, Ligusticum wallichii, rhizoma cyperi processed, the root bark of tree peony, rhizoma atractylodis macrocephalae, interrupted, arisaema cum bile, stir-baked CORTEX EUCOMMIAE and stir-bake to yellowish
Bai Yiqi is crushed, and is crossed 60-80 mesh medicine sieve, is obtained powder II；
(4) powder II is soaked with pure water, kept for 40-60 minutes at 38-45 DEG C of temperature, then using powder II as radix, plus
Enter the pure water of 1.5 times of weight, stir, regulation intermediate pH value is 5.0-6.5, and suitable pH value can keep medicinal material constant
Matter, hydrolyzes 20-24 hours at 55 ± 2 DEG C of temperature, obtains feed liquid I；
(5) press filtration is carried out to feed liquid I using filter press, collects filtrate, obtain feed liquid II, feed liquid II is heated to 55 DEG C -70 DEG C,
Insulation 2 hours, ensure that product quality is stable, high income carries out hyperfiltration afterwards, through high pressure homogenizer homogeneous, collect
It is stand-by that filtrate obtains feed liquid III；
(6) feed liquid III is sufficiently mixed with powder I, adds pill auxiliary material, pill is made, is done in vacuum dryer
It is dry, it is packaged to be finished product.
4. method according to claim 3, it is characterised in that in step (5) homogenization pressure of homogenizer be 15~
20MPa。
5. method according to claim 3, it is characterised in that the feed liquid II in step (5) is after homogeneous through 200 mesh sieve mistakes
Filter.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108853420A (en) * | 2018-09-17 | 2018-11-23 | 山西省人民医院 | Treat the barrenness caused Chinese medicine of polycystic ovary |
| CN111317777A (en) * | 2020-05-08 | 2020-06-23 | 河南中医药大学 | Traditional Chinese medicine decoction for treating kidney deficiency and phlegm dampness type polycystic ovarian syndrome infertility |
| CN117838784A (en) * | 2024-01-09 | 2024-04-09 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medicine composition for treating kidney deficiency and phlegm dampness type polycystic ovary syndrome and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106334060A (en) * | 2016-11-03 | 2017-01-18 | 山东中医药大学附属医院 | Pharmaceutical composition for treating endomorphy type polycystic ovarian syndrome |
-
2017
- 2017-07-10 CN CN201710556540.1A patent/CN107320599A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106334060A (en) * | 2016-11-03 | 2017-01-18 | 山东中医药大学附属医院 | Pharmaceutical composition for treating endomorphy type polycystic ovarian syndrome |
Non-Patent Citations (2)
| Title |
|---|
| 侯丽辉等: "性激素监测中西药治疗多囊卵巢综合征16例", 《中医药学报》 * |
| 衣尚国: "中西医结合治疗多囊卵巢综合征30例", 《吉林中医药》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108853420A (en) * | 2018-09-17 | 2018-11-23 | 山西省人民医院 | Treat the barrenness caused Chinese medicine of polycystic ovary |
| CN111317777A (en) * | 2020-05-08 | 2020-06-23 | 河南中医药大学 | Traditional Chinese medicine decoction for treating kidney deficiency and phlegm dampness type polycystic ovarian syndrome infertility |
| CN117838784A (en) * | 2024-01-09 | 2024-04-09 | 上海中医药大学附属岳阳中西医结合医院 | Traditional Chinese medicine composition for treating kidney deficiency and phlegm dampness type polycystic ovary syndrome and application thereof |
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Application publication date: 20171107 |